data_1QRU
# 
_entry.id   1QRU 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.351 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   1QRU         pdb_00001qru 10.2210/pdb1qru/pdb 
RCSB  PTR011       ?            ?                   
WWPDB D_1000175936 ?            ?                   
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.entry_id                        1QRU 
_pdbx_database_status.recvd_initial_deposition_date   1996-06-14 
_pdbx_database_status.deposit_site                    ? 
_pdbx_database_status.process_site                    NDB 
_pdbx_database_status.status_code_sf                  REL 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.SG_entry                        ? 
_pdbx_database_status.pdb_format_compatible           Y 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
'Arnez, J.G.'  1 
'Steitz, T.A.' 2 
# 
loop_
_citation.id 
_citation.title 
_citation.journal_abbrev 
_citation.journal_volume 
_citation.page_first 
_citation.page_last 
_citation.year 
_citation.journal_id_ASTM 
_citation.country 
_citation.journal_id_ISSN 
_citation.journal_id_CSD 
_citation.book_publisher 
_citation.pdbx_database_id_PubMed 
_citation.pdbx_database_id_DOI 
primary 
'Crystal structures of three misacylating mutants of Escherichia coli glutaminyl-tRNA synthetase complexed with tRNA(Gln) and ATP.' 
Biochemistry           35  14725 14733 1996 BICHAW US 0006-2960 0033 ? 8942633 10.1021/bi961532o 
1       'Structural Basis of Anticodon Loop Recognition by Glutaminyl-tRNA Synthetase' Nature                 352 213   218   1991 
NATUAS UK 0028-0836 0006 ? ?       ?                 
2       'Structural Basis for Misaminoacylation by Mutant E. Coli Glutaminyl-tRNA Synthetase Enzymes' Science                246 
1152  1154  1989 SCIEAS US 0036-8075 0038 ? ?       ?                 
3       'Structure of E. Coli Glutaminyl-tRNA Synthetase Complexed with tRNA(Gln) and ATP at 2.8 A Resolution' Science 246 1135  
1142  1989 SCIEAS US 0036-8075 0038 ? ?       ?                 
4       'Transfer RNA Mischarging Mediated by a Mutant Escherichia Coli Glutaminyl-tRNA Synthetase' Proc.Natl.Acad.Sci.USA 81  
5076  5080  1984 PNASA6 US 0027-8424 0040 ? ?       ?                 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Arnez, J.G.'   1  ? 
primary 'Steitz, T.A.'  2  ? 
1       'Rould, M.A.'   3  ? 
1       'Perona, J.J.'  4  ? 
1       'Steitz, T.A.'  5  ? 
2       'Perona, J.J.'  6  ? 
2       'Swanson, R.N.' 7  ? 
2       'Rould, M.A.'   8  ? 
2       'Steitz, T.A.'  9  ? 
2       'Soll, D.'      10 ? 
3       'Rould, M.A.'   11 ? 
3       'Perona, J.J.'  12 ? 
3       'Soll, D.'      13 ? 
3       'Steitz, T.A.'  14 ? 
4       'Inokuchi, H.'  15 ? 
4       'Hoben, P.'     16 ? 
4       'Yamao, F.'     17 ? 
4       'Ozeki, H.'     18 ? 
4       'Soll, D.'      19 ? 
# 
_cell.entry_id           1QRU 
_cell.length_a           242.000 
_cell.length_b           93.700 
_cell.length_c           115.500 
_cell.angle_alpha        90.00 
_cell.angle_beta         90.00 
_cell.angle_gamma        90.00 
_cell.Z_PDB              8 
_cell.pdbx_unique_axis   ? 
# 
_symmetry.entry_id                         1QRU 
_symmetry.space_group_name_H-M             'C 2 2 21' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                20 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man TRNAGLN2                                              24060.287 1  ?        ?     ? ? 
2 polymer     man 'PROTEIN (GLUTAMINYL-TRNA SYNTHETASE (E.C.6.1.1.18))' 63422.586 1  6.1.1.18 I129T ? ? 
3 non-polymer syn "ADENOSINE-5'-TRIPHOSPHATE"                           507.181   1  ?        ?     ? ? 
4 water       nat water                                                 18.015    14 ?        ?     ? ? 
# 
_entity_keywords.entity_id   2 
_entity_keywords.text        'MUTANT I129T' 
# 
loop_
_entity_name_com.entity_id 
_entity_name_com.name 
1 'GLUTAMINE TRANSFER RNA' 
2 'GLUTAMINYL-TRNA LIGASE' 
# 
loop_
_entity_poly.entity_id 
_entity_poly.type 
_entity_poly.nstd_linkage 
_entity_poly.nstd_monomer 
_entity_poly.pdbx_seq_one_letter_code 
_entity_poly.pdbx_seq_one_letter_code_can 
_entity_poly.pdbx_strand_id 
_entity_poly.pdbx_target_identifier 
1 polyribonucleotide no no UGGGGUAUCGCCAAGCGGUAAGGCACCGGAUUCUGAUUCCGGCAUUCCGAGGUUCGAAUCCUCGUACCCCAGCCA 
UGGGGUAUCGCCAAGCGGUAAGGCACCGGAUUCUGAUUCCGGCAUUCCGAGGUUCGAAUCCUCGUACCCCAGCCA B ? 
2 'polypeptide(L)'   no no 
;SEAEARPTNFIRQIIDEDLASGKHTTVHTRFPPEPNGYLHIGHAKSICLNFGIAQDYKGQCNLRFDDTNPVKEDIEYVES
IKNDVEWLGFHWSGNVRYSSDYFDQLHAYAIELINKGLAYVDELTPEQTREYRGTLTQPGKNSPYRDRSVEENLALFEKM
RAGGFEEGKACLRAKIDMASPFIVMRDPVLYRIKFAEHHQTGNKWCIYPMYDFTHCISDALEGITHSLCTLEFQDNRRLY
DWVLDNITIPVHPRQYEFSRLNLEYTVMSKRKLNLLVTDKHVEGWDDPRMPTISGLRRRGYTAASIREFCKRIGVTKQDN
TIEMASLESCIREDLNENAPRAMAVIDPVKLVIENYQGEGEMVTMPNHPNKPEMGSRQVPFSGEIWIDRADFREEANKQY
KRLVLGKEVRLRNAYVIKAERVEKDAEGNITTIFCTYDADTLSKDPADGRKVKGVIHWVSAAHALPVEIRLYDRLFSVPN
PGAADDFLSVINPESLVIKQGFAEPSLKDAVAGKAFQFEREGYFCLDSRHSTAEKPVFNRTVGLRDTWAKVGE
;
;SEAEARPTNFIRQIIDEDLASGKHTTVHTRFPPEPNGYLHIGHAKSICLNFGIAQDYKGQCNLRFDDTNPVKEDIEYVES
IKNDVEWLGFHWSGNVRYSSDYFDQLHAYAIELINKGLAYVDELTPEQTREYRGTLTQPGKNSPYRDRSVEENLALFEKM
RAGGFEEGKACLRAKIDMASPFIVMRDPVLYRIKFAEHHQTGNKWCIYPMYDFTHCISDALEGITHSLCTLEFQDNRRLY
DWVLDNITIPVHPRQYEFSRLNLEYTVMSKRKLNLLVTDKHVEGWDDPRMPTISGLRRRGYTAASIREFCKRIGVTKQDN
TIEMASLESCIREDLNENAPRAMAVIDPVKLVIENYQGEGEMVTMPNHPNKPEMGSRQVPFSGEIWIDRADFREEANKQY
KRLVLGKEVRLRNAYVIKAERVEKDAEGNITTIFCTYDADTLSKDPADGRKVKGVIHWVSAAHALPVEIRLYDRLFSVPN
PGAADDFLSVINPESLVIKQGFAEPSLKDAVAGKAFQFEREGYFCLDSRHSTAEKPVFNRTVGLRDTWAKVGE
;
A ? 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   U   n 
1 2   G   n 
1 3   G   n 
1 4   G   n 
1 5   G   n 
1 6   U   n 
1 7   A   n 
1 8   U   n 
1 9   C   n 
1 10  G   n 
1 11  C   n 
1 12  C   n 
1 13  A   n 
1 14  A   n 
1 15  G   n 
1 16  C   n 
1 17  G   n 
1 18  G   n 
1 19  U   n 
1 20  A   n 
1 21  A   n 
1 22  G   n 
1 23  G   n 
1 24  C   n 
1 25  A   n 
1 26  C   n 
1 27  C   n 
1 28  G   n 
1 29  G   n 
1 30  A   n 
1 31  U   n 
1 32  U   n 
1 33  C   n 
1 34  U   n 
1 35  G   n 
1 36  A   n 
1 37  U   n 
1 38  U   n 
1 39  C   n 
1 40  C   n 
1 41  G   n 
1 42  G   n 
1 43  C   n 
1 44  A   n 
1 45  U   n 
1 46  U   n 
1 47  C   n 
1 48  C   n 
1 49  G   n 
1 50  A   n 
1 51  G   n 
1 52  G   n 
1 53  U   n 
1 54  U   n 
1 55  C   n 
1 56  G   n 
1 57  A   n 
1 58  A   n 
1 59  U   n 
1 60  C   n 
1 61  C   n 
1 62  U   n 
1 63  C   n 
1 64  G   n 
1 65  U   n 
1 66  A   n 
1 67  C   n 
1 68  C   n 
1 69  C   n 
1 70  C   n 
1 71  A   n 
1 72  G   n 
1 73  C   n 
1 74  C   n 
1 75  A   n 
2 1   SER n 
2 2   GLU n 
2 3   ALA n 
2 4   GLU n 
2 5   ALA n 
2 6   ARG n 
2 7   PRO n 
2 8   THR n 
2 9   ASN n 
2 10  PHE n 
2 11  ILE n 
2 12  ARG n 
2 13  GLN n 
2 14  ILE n 
2 15  ILE n 
2 16  ASP n 
2 17  GLU n 
2 18  ASP n 
2 19  LEU n 
2 20  ALA n 
2 21  SER n 
2 22  GLY n 
2 23  LYS n 
2 24  HIS n 
2 25  THR n 
2 26  THR n 
2 27  VAL n 
2 28  HIS n 
2 29  THR n 
2 30  ARG n 
2 31  PHE n 
2 32  PRO n 
2 33  PRO n 
2 34  GLU n 
2 35  PRO n 
2 36  ASN n 
2 37  GLY n 
2 38  TYR n 
2 39  LEU n 
2 40  HIS n 
2 41  ILE n 
2 42  GLY n 
2 43  HIS n 
2 44  ALA n 
2 45  LYS n 
2 46  SER n 
2 47  ILE n 
2 48  CYS n 
2 49  LEU n 
2 50  ASN n 
2 51  PHE n 
2 52  GLY n 
2 53  ILE n 
2 54  ALA n 
2 55  GLN n 
2 56  ASP n 
2 57  TYR n 
2 58  LYS n 
2 59  GLY n 
2 60  GLN n 
2 61  CYS n 
2 62  ASN n 
2 63  LEU n 
2 64  ARG n 
2 65  PHE n 
2 66  ASP n 
2 67  ASP n 
2 68  THR n 
2 69  ASN n 
2 70  PRO n 
2 71  VAL n 
2 72  LYS n 
2 73  GLU n 
2 74  ASP n 
2 75  ILE n 
2 76  GLU n 
2 77  TYR n 
2 78  VAL n 
2 79  GLU n 
2 80  SER n 
2 81  ILE n 
2 82  LYS n 
2 83  ASN n 
2 84  ASP n 
2 85  VAL n 
2 86  GLU n 
2 87  TRP n 
2 88  LEU n 
2 89  GLY n 
2 90  PHE n 
2 91  HIS n 
2 92  TRP n 
2 93  SER n 
2 94  GLY n 
2 95  ASN n 
2 96  VAL n 
2 97  ARG n 
2 98  TYR n 
2 99  SER n 
2 100 SER n 
2 101 ASP n 
2 102 TYR n 
2 103 PHE n 
2 104 ASP n 
2 105 GLN n 
2 106 LEU n 
2 107 HIS n 
2 108 ALA n 
2 109 TYR n 
2 110 ALA n 
2 111 ILE n 
2 112 GLU n 
2 113 LEU n 
2 114 ILE n 
2 115 ASN n 
2 116 LYS n 
2 117 GLY n 
2 118 LEU n 
2 119 ALA n 
2 120 TYR n 
2 121 VAL n 
2 122 ASP n 
2 123 GLU n 
2 124 LEU n 
2 125 THR n 
2 126 PRO n 
2 127 GLU n 
2 128 GLN n 
2 129 THR n 
2 130 ARG n 
2 131 GLU n 
2 132 TYR n 
2 133 ARG n 
2 134 GLY n 
2 135 THR n 
2 136 LEU n 
2 137 THR n 
2 138 GLN n 
2 139 PRO n 
2 140 GLY n 
2 141 LYS n 
2 142 ASN n 
2 143 SER n 
2 144 PRO n 
2 145 TYR n 
2 146 ARG n 
2 147 ASP n 
2 148 ARG n 
2 149 SER n 
2 150 VAL n 
2 151 GLU n 
2 152 GLU n 
2 153 ASN n 
2 154 LEU n 
2 155 ALA n 
2 156 LEU n 
2 157 PHE n 
2 158 GLU n 
2 159 LYS n 
2 160 MET n 
2 161 ARG n 
2 162 ALA n 
2 163 GLY n 
2 164 GLY n 
2 165 PHE n 
2 166 GLU n 
2 167 GLU n 
2 168 GLY n 
2 169 LYS n 
2 170 ALA n 
2 171 CYS n 
2 172 LEU n 
2 173 ARG n 
2 174 ALA n 
2 175 LYS n 
2 176 ILE n 
2 177 ASP n 
2 178 MET n 
2 179 ALA n 
2 180 SER n 
2 181 PRO n 
2 182 PHE n 
2 183 ILE n 
2 184 VAL n 
2 185 MET n 
2 186 ARG n 
2 187 ASP n 
2 188 PRO n 
2 189 VAL n 
2 190 LEU n 
2 191 TYR n 
2 192 ARG n 
2 193 ILE n 
2 194 LYS n 
2 195 PHE n 
2 196 ALA n 
2 197 GLU n 
2 198 HIS n 
2 199 HIS n 
2 200 GLN n 
2 201 THR n 
2 202 GLY n 
2 203 ASN n 
2 204 LYS n 
2 205 TRP n 
2 206 CYS n 
2 207 ILE n 
2 208 TYR n 
2 209 PRO n 
2 210 MET n 
2 211 TYR n 
2 212 ASP n 
2 213 PHE n 
2 214 THR n 
2 215 HIS n 
2 216 CYS n 
2 217 ILE n 
2 218 SER n 
2 219 ASP n 
2 220 ALA n 
2 221 LEU n 
2 222 GLU n 
2 223 GLY n 
2 224 ILE n 
2 225 THR n 
2 226 HIS n 
2 227 SER n 
2 228 LEU n 
2 229 CYS n 
2 230 THR n 
2 231 LEU n 
2 232 GLU n 
2 233 PHE n 
2 234 GLN n 
2 235 ASP n 
2 236 ASN n 
2 237 ARG n 
2 238 ARG n 
2 239 LEU n 
2 240 TYR n 
2 241 ASP n 
2 242 TRP n 
2 243 VAL n 
2 244 LEU n 
2 245 ASP n 
2 246 ASN n 
2 247 ILE n 
2 248 THR n 
2 249 ILE n 
2 250 PRO n 
2 251 VAL n 
2 252 HIS n 
2 253 PRO n 
2 254 ARG n 
2 255 GLN n 
2 256 TYR n 
2 257 GLU n 
2 258 PHE n 
2 259 SER n 
2 260 ARG n 
2 261 LEU n 
2 262 ASN n 
2 263 LEU n 
2 264 GLU n 
2 265 TYR n 
2 266 THR n 
2 267 VAL n 
2 268 MET n 
2 269 SER n 
2 270 LYS n 
2 271 ARG n 
2 272 LYS n 
2 273 LEU n 
2 274 ASN n 
2 275 LEU n 
2 276 LEU n 
2 277 VAL n 
2 278 THR n 
2 279 ASP n 
2 280 LYS n 
2 281 HIS n 
2 282 VAL n 
2 283 GLU n 
2 284 GLY n 
2 285 TRP n 
2 286 ASP n 
2 287 ASP n 
2 288 PRO n 
2 289 ARG n 
2 290 MET n 
2 291 PRO n 
2 292 THR n 
2 293 ILE n 
2 294 SER n 
2 295 GLY n 
2 296 LEU n 
2 297 ARG n 
2 298 ARG n 
2 299 ARG n 
2 300 GLY n 
2 301 TYR n 
2 302 THR n 
2 303 ALA n 
2 304 ALA n 
2 305 SER n 
2 306 ILE n 
2 307 ARG n 
2 308 GLU n 
2 309 PHE n 
2 310 CYS n 
2 311 LYS n 
2 312 ARG n 
2 313 ILE n 
2 314 GLY n 
2 315 VAL n 
2 316 THR n 
2 317 LYS n 
2 318 GLN n 
2 319 ASP n 
2 320 ASN n 
2 321 THR n 
2 322 ILE n 
2 323 GLU n 
2 324 MET n 
2 325 ALA n 
2 326 SER n 
2 327 LEU n 
2 328 GLU n 
2 329 SER n 
2 330 CYS n 
2 331 ILE n 
2 332 ARG n 
2 333 GLU n 
2 334 ASP n 
2 335 LEU n 
2 336 ASN n 
2 337 GLU n 
2 338 ASN n 
2 339 ALA n 
2 340 PRO n 
2 341 ARG n 
2 342 ALA n 
2 343 MET n 
2 344 ALA n 
2 345 VAL n 
2 346 ILE n 
2 347 ASP n 
2 348 PRO n 
2 349 VAL n 
2 350 LYS n 
2 351 LEU n 
2 352 VAL n 
2 353 ILE n 
2 354 GLU n 
2 355 ASN n 
2 356 TYR n 
2 357 GLN n 
2 358 GLY n 
2 359 GLU n 
2 360 GLY n 
2 361 GLU n 
2 362 MET n 
2 363 VAL n 
2 364 THR n 
2 365 MET n 
2 366 PRO n 
2 367 ASN n 
2 368 HIS n 
2 369 PRO n 
2 370 ASN n 
2 371 LYS n 
2 372 PRO n 
2 373 GLU n 
2 374 MET n 
2 375 GLY n 
2 376 SER n 
2 377 ARG n 
2 378 GLN n 
2 379 VAL n 
2 380 PRO n 
2 381 PHE n 
2 382 SER n 
2 383 GLY n 
2 384 GLU n 
2 385 ILE n 
2 386 TRP n 
2 387 ILE n 
2 388 ASP n 
2 389 ARG n 
2 390 ALA n 
2 391 ASP n 
2 392 PHE n 
2 393 ARG n 
2 394 GLU n 
2 395 GLU n 
2 396 ALA n 
2 397 ASN n 
2 398 LYS n 
2 399 GLN n 
2 400 TYR n 
2 401 LYS n 
2 402 ARG n 
2 403 LEU n 
2 404 VAL n 
2 405 LEU n 
2 406 GLY n 
2 407 LYS n 
2 408 GLU n 
2 409 VAL n 
2 410 ARG n 
2 411 LEU n 
2 412 ARG n 
2 413 ASN n 
2 414 ALA n 
2 415 TYR n 
2 416 VAL n 
2 417 ILE n 
2 418 LYS n 
2 419 ALA n 
2 420 GLU n 
2 421 ARG n 
2 422 VAL n 
2 423 GLU n 
2 424 LYS n 
2 425 ASP n 
2 426 ALA n 
2 427 GLU n 
2 428 GLY n 
2 429 ASN n 
2 430 ILE n 
2 431 THR n 
2 432 THR n 
2 433 ILE n 
2 434 PHE n 
2 435 CYS n 
2 436 THR n 
2 437 TYR n 
2 438 ASP n 
2 439 ALA n 
2 440 ASP n 
2 441 THR n 
2 442 LEU n 
2 443 SER n 
2 444 LYS n 
2 445 ASP n 
2 446 PRO n 
2 447 ALA n 
2 448 ASP n 
2 449 GLY n 
2 450 ARG n 
2 451 LYS n 
2 452 VAL n 
2 453 LYS n 
2 454 GLY n 
2 455 VAL n 
2 456 ILE n 
2 457 HIS n 
2 458 TRP n 
2 459 VAL n 
2 460 SER n 
2 461 ALA n 
2 462 ALA n 
2 463 HIS n 
2 464 ALA n 
2 465 LEU n 
2 466 PRO n 
2 467 VAL n 
2 468 GLU n 
2 469 ILE n 
2 470 ARG n 
2 471 LEU n 
2 472 TYR n 
2 473 ASP n 
2 474 ARG n 
2 475 LEU n 
2 476 PHE n 
2 477 SER n 
2 478 VAL n 
2 479 PRO n 
2 480 ASN n 
2 481 PRO n 
2 482 GLY n 
2 483 ALA n 
2 484 ALA n 
2 485 ASP n 
2 486 ASP n 
2 487 PHE n 
2 488 LEU n 
2 489 SER n 
2 490 VAL n 
2 491 ILE n 
2 492 ASN n 
2 493 PRO n 
2 494 GLU n 
2 495 SER n 
2 496 LEU n 
2 497 VAL n 
2 498 ILE n 
2 499 LYS n 
2 500 GLN n 
2 501 GLY n 
2 502 PHE n 
2 503 ALA n 
2 504 GLU n 
2 505 PRO n 
2 506 SER n 
2 507 LEU n 
2 508 LYS n 
2 509 ASP n 
2 510 ALA n 
2 511 VAL n 
2 512 ALA n 
2 513 GLY n 
2 514 LYS n 
2 515 ALA n 
2 516 PHE n 
2 517 GLN n 
2 518 PHE n 
2 519 GLU n 
2 520 ARG n 
2 521 GLU n 
2 522 GLY n 
2 523 TYR n 
2 524 PHE n 
2 525 CYS n 
2 526 LEU n 
2 527 ASP n 
2 528 SER n 
2 529 ARG n 
2 530 HIS n 
2 531 SER n 
2 532 THR n 
2 533 ALA n 
2 534 GLU n 
2 535 LYS n 
2 536 PRO n 
2 537 VAL n 
2 538 PHE n 
2 539 ASN n 
2 540 ARG n 
2 541 THR n 
2 542 VAL n 
2 543 GLY n 
2 544 LEU n 
2 545 ARG n 
2 546 ASP n 
2 547 THR n 
2 548 TRP n 
2 549 ALA n 
2 550 LYS n 
2 551 VAL n 
2 552 GLY n 
2 553 GLU n 
# 
loop_
_entity_src_gen.entity_id 
_entity_src_gen.pdbx_src_id 
_entity_src_gen.pdbx_alt_source_flag 
_entity_src_gen.pdbx_seq_type 
_entity_src_gen.pdbx_beg_seq_num 
_entity_src_gen.pdbx_end_seq_num 
_entity_src_gen.gene_src_common_name 
_entity_src_gen.gene_src_genus 
_entity_src_gen.pdbx_gene_src_gene 
_entity_src_gen.gene_src_species 
_entity_src_gen.gene_src_strain 
_entity_src_gen.gene_src_tissue 
_entity_src_gen.gene_src_tissue_fraction 
_entity_src_gen.gene_src_details 
_entity_src_gen.pdbx_gene_src_fragment 
_entity_src_gen.pdbx_gene_src_scientific_name 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 
_entity_src_gen.pdbx_gene_src_variant 
_entity_src_gen.pdbx_gene_src_cell_line 
_entity_src_gen.pdbx_gene_src_atcc 
_entity_src_gen.pdbx_gene_src_organ 
_entity_src_gen.pdbx_gene_src_organelle 
_entity_src_gen.pdbx_gene_src_cell 
_entity_src_gen.pdbx_gene_src_cellular_location 
_entity_src_gen.host_org_common_name 
_entity_src_gen.pdbx_host_org_scientific_name 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 
_entity_src_gen.host_org_genus 
_entity_src_gen.pdbx_host_org_gene 
_entity_src_gen.pdbx_host_org_organ 
_entity_src_gen.host_org_species 
_entity_src_gen.pdbx_host_org_tissue 
_entity_src_gen.pdbx_host_org_tissue_fraction 
_entity_src_gen.pdbx_host_org_strain 
_entity_src_gen.pdbx_host_org_variant 
_entity_src_gen.pdbx_host_org_cell_line 
_entity_src_gen.pdbx_host_org_atcc 
_entity_src_gen.pdbx_host_org_culture_collection 
_entity_src_gen.pdbx_host_org_cell 
_entity_src_gen.pdbx_host_org_organelle 
_entity_src_gen.pdbx_host_org_cellular_location 
_entity_src_gen.pdbx_host_org_vector_type 
_entity_src_gen.pdbx_host_org_vector 
_entity_src_gen.host_org_details 
_entity_src_gen.expression_system_id 
_entity_src_gen.plasmid_name 
_entity_src_gen.plasmid_details 
_entity_src_gen.pdbx_description 
1 1 sample ? ? ? ? Escherichia TRNAGLN2 ? K-12                          ? ? ? ? 'Escherichia coli' 562 DELTAH1DELTATRP ? ? ? ? ? ? 
? 'Escherichia coli' 562 Escherichia TRNAGLN2 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 'PRS3 (PLC28 DERIVATIVE)'      'PLC28 DERIVATIVE'  
'LAMBDA PL PROMOTER'                
2 1 sample ? ? ? ? Escherichia GLNS15   ? 'X3R2 (GLNS DELETION STRAIN)' ? ? ? ? 'Escherichia coli' 562 ?               ? ? ? ? ? ? 
? 'Escherichia coli' 562 Escherichia GLNS15   ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 'PRS12 (DERIVATIVE OF PBR322)' 'DERIVATIVE OF PBR' 
'GLNS PROMOTER (NO OVEREXPRESSION)' 
# 
loop_
_struct_ref.id 
_struct_ref.db_name 
_struct_ref.db_code 
_struct_ref.entity_id 
_struct_ref.pdbx_seq_one_letter_code 
_struct_ref.pdbx_align_begin 
_struct_ref.pdbx_db_accession 
_struct_ref.pdbx_db_isoform 
1 UNP SYQ_ECOLI 2 ? ? P00962 ? 
2 PDB 1QRU      1 ? ? 1QRU   ? 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 1QRU A 1 ? 553 ? P00962 1 ? 553 ? 1 553 
2 2 1QRU B 1 ? 75  ? 1QRU   1 ? 76  ? 1 76  
# 
_struct_ref_seq_dif.align_id                     1 
_struct_ref_seq_dif.pdbx_pdb_id_code             1QRU 
_struct_ref_seq_dif.mon_id                       THR 
_struct_ref_seq_dif.pdbx_pdb_strand_id           A 
_struct_ref_seq_dif.seq_num                      129 
_struct_ref_seq_dif.pdbx_pdb_ins_code            ? 
_struct_ref_seq_dif.pdbx_seq_db_name             UNP 
_struct_ref_seq_dif.pdbx_seq_db_accession_code   P00962 
_struct_ref_seq_dif.db_mon_id                    ILE 
_struct_ref_seq_dif.pdbx_seq_db_seq_num          129 
_struct_ref_seq_dif.details                      'engineered mutation' 
_struct_ref_seq_dif.pdbx_auth_seq_num            129 
_struct_ref_seq_dif.pdbx_ordinal                 1 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
A   'RNA linking'       y "ADENOSINE-5'-MONOPHOSPHATE" ? 'C10 H14 N5 O7 P'   347.221 
ALA 'L-peptide linking' y ALANINE                      ? 'C3 H7 N O2'        89.093  
ARG 'L-peptide linking' y ARGININE                     ? 'C6 H15 N4 O2 1'    175.209 
ASN 'L-peptide linking' y ASPARAGINE                   ? 'C4 H8 N2 O3'       132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID'              ? 'C4 H7 N O4'        133.103 
ATP non-polymer         . "ADENOSINE-5'-TRIPHOSPHATE"  ? 'C10 H16 N5 O13 P3' 507.181 
C   'RNA linking'       y "CYTIDINE-5'-MONOPHOSPHATE"  ? 'C9 H14 N3 O8 P'    323.197 
CYS 'L-peptide linking' y CYSTEINE                     ? 'C3 H7 N O2 S'      121.158 
G   'RNA linking'       y "GUANOSINE-5'-MONOPHOSPHATE" ? 'C10 H14 N5 O8 P'   363.221 
GLN 'L-peptide linking' y GLUTAMINE                    ? 'C5 H10 N2 O3'      146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID'              ? 'C5 H9 N O4'        147.129 
GLY 'peptide linking'   y GLYCINE                      ? 'C2 H5 N O2'        75.067  
HIS 'L-peptide linking' y HISTIDINE                    ? 'C6 H10 N3 O2 1'    156.162 
HOH non-polymer         . WATER                        ? 'H2 O'              18.015  
ILE 'L-peptide linking' y ISOLEUCINE                   ? 'C6 H13 N O2'       131.173 
LEU 'L-peptide linking' y LEUCINE                      ? 'C6 H13 N O2'       131.173 
LYS 'L-peptide linking' y LYSINE                       ? 'C6 H15 N2 O2 1'    147.195 
MET 'L-peptide linking' y METHIONINE                   ? 'C5 H11 N O2 S'     149.211 
PHE 'L-peptide linking' y PHENYLALANINE                ? 'C9 H11 N O2'       165.189 
PRO 'L-peptide linking' y PROLINE                      ? 'C5 H9 N O2'        115.130 
SER 'L-peptide linking' y SERINE                       ? 'C3 H7 N O3'        105.093 
THR 'L-peptide linking' y THREONINE                    ? 'C4 H9 N O3'        119.119 
TRP 'L-peptide linking' y TRYPTOPHAN                   ? 'C11 H12 N2 O2'     204.225 
TYR 'L-peptide linking' y TYROSINE                     ? 'C9 H11 N O3'       181.189 
U   'RNA linking'       y "URIDINE-5'-MONOPHOSPHATE"   ? 'C9 H13 N2 O9 P'    324.181 
VAL 'L-peptide linking' y VALINE                       ? 'C5 H11 N O2'       117.146 
# 
_exptl.entry_id          1QRU 
_exptl.method            'X-RAY DIFFRACTION' 
_exptl.crystals_number   ? 
# 
_exptl_crystal.id                    1 
_exptl_crystal.density_meas          ? 
_exptl_crystal.density_Matthews      3.74 
_exptl_crystal.density_percent_sol   70.0000 
_exptl_crystal.description           ? 
# 
_diffrn.id                     1 
_diffrn.ambient_temp           ? 
_diffrn.ambient_temp_details   ? 
_diffrn.crystal_id             1 
# 
_diffrn_detector.diffrn_id              1 
_diffrn_detector.detector               'AREA DETECTOR' 
_diffrn_detector.type                   SDMS 
_diffrn_detector.pdbx_collection_date   1989-12-01 
_diffrn_detector.details                ? 
# 
_diffrn_radiation.diffrn_id                        1 
_diffrn_radiation.wavelength_id                    1 
_diffrn_radiation.pdbx_monochromatic_or_laue_m_l   M 
_diffrn_radiation.monochromator                    ? 
_diffrn_radiation.pdbx_diffrn_protocol             'SINGLE WAVELENGTH' 
_diffrn_radiation.pdbx_scattering_type             x-ray 
# 
_diffrn_radiation_wavelength.id           1 
_diffrn_radiation_wavelength.wavelength   . 
_diffrn_radiation_wavelength.wt           1.0 
# 
_diffrn_source.diffrn_id                   1 
_diffrn_source.source                      ? 
_diffrn_source.type                        ? 
_diffrn_source.pdbx_synchrotron_site       ? 
_diffrn_source.pdbx_synchrotron_beamline   ? 
_diffrn_source.pdbx_wavelength             ? 
_diffrn_source.pdbx_wavelength_list        ? 
# 
_reflns.entry_id                     1QRU 
_reflns.observed_criterion_sigma_I   0.000 
_reflns.observed_criterion_sigma_F   ? 
_reflns.d_resolution_low             ? 
_reflns.d_resolution_high            ? 
_reflns.number_obs                   23275 
_reflns.number_all                   ? 
_reflns.percent_possible_obs         90.700 
_reflns.pdbx_Rmerge_I_obs            0.0970000 
_reflns.pdbx_Rsym_value              ? 
_reflns.pdbx_netI_over_sigmaI        ? 
_reflns.B_iso_Wilson_estimate        ? 
_reflns.pdbx_redundancy              2.700 
_reflns.R_free_details               ? 
_reflns.pdbx_diffrn_id               1 
_reflns.pdbx_ordinal                 1 
# 
_refine.entry_id                                 1QRU 
_refine.ls_number_reflns_obs                     22183 
_refine.ls_number_reflns_all                     ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          0.000 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.ls_d_res_low                             7.000 
_refine.ls_d_res_high                            3.000 
_refine.ls_percent_reflns_obs                    ? 
_refine.ls_R_factor_obs                          0.2300000 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_R_work                       0.2300000 
_refine.ls_R_factor_R_free                       ? 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_percent_reflns_R_free                 ? 
_refine.ls_number_reflns_R_free                  ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_restraints                     ? 
_refine.occupancy_min                            ? 
_refine.occupancy_max                            ? 
_refine.B_iso_mean                               ? 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.solvent_model_details                    ? 
_refine.solvent_model_param_ksol                 ? 
_refine.solvent_model_param_bsol                 ? 
_refine.pdbx_ls_cross_valid_method               ? 
_refine.details                                  ? 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_method_to_determine_struct          ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_stereochemistry_target_values       ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.overall_SU_ML                            ? 
_refine.overall_SU_B                             ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.pdbx_refine_id                           'X-RAY DIFFRACTION' 
_refine.pdbx_diffrn_id                           1 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_solvent_vdw_probe_radii             ? 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
# 
_refine_hist.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_hist.cycle_id                         LAST 
_refine_hist.pdbx_number_atoms_protein        5254 
_refine_hist.pdbx_number_atoms_nucleic_acid   1802 
_refine_hist.pdbx_number_atoms_ligand         34 
_refine_hist.number_atoms_solvent             14 
_refine_hist.number_atoms_total               7104 
_refine_hist.d_res_high                       3.000 
_refine_hist.d_res_low                        7.000 
# 
loop_
_refine_ls_restr.type 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.weight 
_refine_ls_restr.number 
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.pdbx_restraint_function 
x_bond_d                0.013 ? ? ? 'X-RAY DIFFRACTION' ? 
x_bond_d_na             ?     ? ? ? 'X-RAY DIFFRACTION' ? 
x_bond_d_prot           ?     ? ? ? 'X-RAY DIFFRACTION' ? 
x_angle_d               ?     ? ? ? 'X-RAY DIFFRACTION' ? 
x_angle_d_na            ?     ? ? ? 'X-RAY DIFFRACTION' ? 
x_angle_d_prot          ?     ? ? ? 'X-RAY DIFFRACTION' ? 
x_angle_deg             1.65  ? ? ? 'X-RAY DIFFRACTION' ? 
x_angle_deg_na          ?     ? ? ? 'X-RAY DIFFRACTION' ? 
x_angle_deg_prot        ?     ? ? ? 'X-RAY DIFFRACTION' ? 
x_dihedral_angle_d      ?     ? ? ? 'X-RAY DIFFRACTION' ? 
x_dihedral_angle_d_na   ?     ? ? ? 'X-RAY DIFFRACTION' ? 
x_dihedral_angle_d_prot ?     ? ? ? 'X-RAY DIFFRACTION' ? 
x_improper_angle_d      ?     ? ? ? 'X-RAY DIFFRACTION' ? 
x_improper_angle_d_na   ?     ? ? ? 'X-RAY DIFFRACTION' ? 
x_improper_angle_d_prot ?     ? ? ? 'X-RAY DIFFRACTION' ? 
x_mcbond_it             ?     ? ? ? 'X-RAY DIFFRACTION' ? 
x_mcangle_it            ?     ? ? ? 'X-RAY DIFFRACTION' ? 
x_scbond_it             ?     ? ? ? 'X-RAY DIFFRACTION' ? 
x_scangle_it            ?     ? ? ? 'X-RAY DIFFRACTION' ? 
# 
_struct.entry_id                  1QRU 
_struct.title                     'GLUTAMINYL-TRNA SYNTHETASE MUTANT I129T COMPLEXED WITH GLUTAMINE TRANSFER RNA' 
_struct.pdbx_model_details        ? 
_struct.pdbx_CASP_flag            ? 
_struct.pdbx_model_type_details   ? 
# 
_struct_keywords.entry_id        1QRU 
_struct_keywords.pdbx_keywords   LIGASE/RNA 
_struct_keywords.text            
'AMINOACYL-TRNA SYNTHASE, PROTEIN BIOSYNTHESIS, LIGASE, ATP-B, COMPLEX (AMINOACYL-TRNA SYNTHASE-TRNA), LIGASE-RNA COMPLEX' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 3 ? 
D N N 4 ? 
E N N 4 ? 
# 
_struct_biol.id                    1 
_struct_biol.pdbx_parent_biol_id   ? 
_struct_biol.details               ? 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  1  PHE B 10  ? ALA B 20  ? PHE A 10  ALA A 20  1 ? 11 
HELX_P HELX_P2  2  ILE B 41  ? ASP B 56  ? ILE A 41  ASP A 56  1 ? 16 
HELX_P HELX_P3  3  ILE B 75  ? TRP B 87  ? ILE A 75  TRP A 87  1 ? 13 
HELX_P HELX_P4  4  SER B 99  ? ASN B 115 ? SER A 99  ASN A 115 5 ? 17 
HELX_P HELX_P5  5  PRO B 126 ? ARG B 133 ? PRO A 126 ARG A 133 1 ? 8  
HELX_P HELX_P6  6  VAL B 150 ? ARG B 161 ? VAL A 150 ARG A 161 1 ? 12 
HELX_P HELX_P7  7  ILE B 183 ? MET B 185 ? ILE A 183 MET A 185 5 ? 3  
HELX_P HELX_P8  8  TYR B 211 ? GLU B 222 ? TYR A 211 GLU A 222 1 ? 12 
HELX_P HELX_P9  9  LEU B 231 ? PHE B 233 ? LEU A 231 PHE A 233 5 ? 3  
HELX_P HELX_P10 10 ASN B 236 ? ASN B 246 ? ASN A 236 ASN A 246 5 ? 11 
HELX_P HELX_P11 11 LYS B 270 ? THR B 278 ? LYS A 270 THR A 278 1 ? 9  
HELX_P HELX_P12 12 ILE B 293 ? ARG B 299 ? ILE A 293 ARG A 299 1 ? 7  
HELX_P HELX_P13 13 ALA B 303 ? ILE B 313 ? ALA A 303 ILE A 313 1 ? 11 
HELX_P HELX_P14 14 MET B 324 ? ASN B 338 ? MET A 324 ASN A 338 1 ? 15 
HELX_P HELX_P15 15 PRO B 372 ? MET B 374 ? PRO A 372 MET A 374 5 ? 3  
HELX_P HELX_P16 16 ARG B 389 ? ASP B 391 ? ARG A 389 ASP A 391 5 ? 3  
HELX_P HELX_P17 17 ALA B 461 ? HIS B 463 ? ALA A 461 HIS A 463 5 ? 3  
HELX_P HELX_P18 18 PRO B 481 ? ALA B 483 ? PRO A 481 ALA A 483 5 ? 3  
HELX_P HELX_P19 19 PHE B 487 ? VAL B 490 ? PHE A 487 VAL A 490 5 ? 4  
HELX_P HELX_P20 20 PRO B 505 ? ASP B 509 ? PRO A 505 ASP A 509 5 ? 5  
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
hydrog1  hydrog ? ? A G 2  N1 ? ? ? 1_555 A C 70 N3 ? ? B G 2  B C 71 1_555 ? ? ? ? ? ? WATSON-CRICK            ? ? ? 
hydrog2  hydrog ? ? A G 2  N2 ? ? ? 1_555 A C 70 O2 ? ? B G 2  B C 71 1_555 ? ? ? ? ? ? WATSON-CRICK            ? ? ? 
hydrog3  hydrog ? ? A G 2  O6 ? ? ? 1_555 A C 70 N4 ? ? B G 2  B C 71 1_555 ? ? ? ? ? ? WATSON-CRICK            ? ? ? 
hydrog4  hydrog ? ? A G 3  N1 ? ? ? 1_555 A C 69 N3 ? ? B G 3  B C 70 1_555 ? ? ? ? ? ? WATSON-CRICK            ? ? ? 
hydrog5  hydrog ? ? A G 3  N2 ? ? ? 1_555 A C 69 O2 ? ? B G 3  B C 70 1_555 ? ? ? ? ? ? WATSON-CRICK            ? ? ? 
hydrog6  hydrog ? ? A G 3  O6 ? ? ? 1_555 A C 69 N4 ? ? B G 3  B C 70 1_555 ? ? ? ? ? ? WATSON-CRICK            ? ? ? 
hydrog7  hydrog ? ? A G 4  N1 ? ? ? 1_555 A C 68 N3 ? ? B G 4  B C 69 1_555 ? ? ? ? ? ? WATSON-CRICK            ? ? ? 
hydrog8  hydrog ? ? A G 4  N2 ? ? ? 1_555 A C 68 O2 ? ? B G 4  B C 69 1_555 ? ? ? ? ? ? WATSON-CRICK            ? ? ? 
hydrog9  hydrog ? ? A G 4  O6 ? ? ? 1_555 A C 68 N4 ? ? B G 4  B C 69 1_555 ? ? ? ? ? ? WATSON-CRICK            ? ? ? 
hydrog10 hydrog ? ? A G 5  N1 ? ? ? 1_555 A C 67 N3 ? ? B G 5  B C 68 1_555 ? ? ? ? ? ? WATSON-CRICK            ? ? ? 
hydrog11 hydrog ? ? A G 5  N2 ? ? ? 1_555 A C 67 O2 ? ? B G 5  B C 68 1_555 ? ? ? ? ? ? WATSON-CRICK            ? ? ? 
hydrog12 hydrog ? ? A G 5  O6 ? ? ? 1_555 A C 67 N4 ? ? B G 5  B C 68 1_555 ? ? ? ? ? ? WATSON-CRICK            ? ? ? 
hydrog13 hydrog ? ? A U 6  N3 ? ? ? 1_555 A A 66 N1 ? ? B U 6  B A 67 1_555 ? ? ? ? ? ? WATSON-CRICK            ? ? ? 
hydrog14 hydrog ? ? A U 6  O4 ? ? ? 1_555 A A 66 N6 ? ? B U 6  B A 67 1_555 ? ? ? ? ? ? WATSON-CRICK            ? ? ? 
hydrog15 hydrog ? ? A A 7  N1 ? ? ? 1_555 A U 65 N3 ? ? B A 7  B U 66 1_555 ? ? ? ? ? ? WATSON-CRICK            ? ? ? 
hydrog16 hydrog ? ? A A 7  N6 ? ? ? 1_555 A U 65 O4 ? ? B A 7  B U 66 1_555 ? ? ? ? ? ? WATSON-CRICK            ? ? ? 
hydrog17 hydrog ? ? A U 8  N3 ? ? ? 1_555 A A 14 N7 ? ? B U 8  B A 14 1_555 ? ? ? ? ? ? 'REVERSED HOOGSTEEN'    ? ? ? 
hydrog18 hydrog ? ? A U 8  O2 ? ? ? 1_555 A A 14 N6 ? ? B U 8  B A 14 1_555 ? ? ? ? ? ? 'REVERSED HOOGSTEEN'    ? ? ? 
hydrog19 hydrog ? ? A C 9  N4 ? ? ? 1_555 A G 22 O6 ? ? B C 9  B G 23 1_555 ? ? ? ? ? ? 'C-G PAIR'              ? ? ? 
hydrog20 hydrog ? ? A G 10 N1 ? ? ? 1_555 A C 24 N3 ? ? B G 10 B C 25 1_555 ? ? ? ? ? ? WATSON-CRICK            ? ? ? 
hydrog21 hydrog ? ? A G 10 N2 ? ? ? 1_555 A C 24 O2 ? ? B G 10 B C 25 1_555 ? ? ? ? ? ? WATSON-CRICK            ? ? ? 
hydrog22 hydrog ? ? A G 10 O6 ? ? ? 1_555 A C 24 N4 ? ? B G 10 B C 25 1_555 ? ? ? ? ? ? WATSON-CRICK            ? ? ? 
hydrog23 hydrog ? ? A C 11 N3 ? ? ? 1_555 A G 23 N1 ? ? B C 11 B G 24 1_555 ? ? ? ? ? ? WATSON-CRICK            ? ? ? 
hydrog24 hydrog ? ? A C 11 N4 ? ? ? 1_555 A G 23 O6 ? ? B C 11 B G 24 1_555 ? ? ? ? ? ? WATSON-CRICK            ? ? ? 
hydrog25 hydrog ? ? A C 11 O2 ? ? ? 1_555 A G 23 N2 ? ? B C 11 B G 24 1_555 ? ? ? ? ? ? WATSON-CRICK            ? ? ? 
hydrog26 hydrog ? ? A C 12 N3 ? ? ? 1_555 A G 22 N1 ? ? B C 12 B G 23 1_555 ? ? ? ? ? ? WATSON-CRICK            ? ? ? 
hydrog27 hydrog ? ? A C 12 N4 ? ? ? 1_555 A G 22 O6 ? ? B C 12 B G 23 1_555 ? ? ? ? ? ? WATSON-CRICK            ? ? ? 
hydrog28 hydrog ? ? A C 12 O2 ? ? ? 1_555 A G 22 N2 ? ? B C 12 B G 23 1_555 ? ? ? ? ? ? WATSON-CRICK            ? ? ? 
hydrog29 hydrog ? ? A A 13 N3 ? ? ? 1_555 A A 21 N6 ? ? B A 13 B A 22 1_555 ? ? ? ? ? ? 'A-A MISPAIR'           ? ? ? 
hydrog30 hydrog ? ? A A 13 N1 ? ? ? 1_555 A A 44 N6 ? ? B A 13 B A 45 1_555 ? ? ? ? ? ? TYPE_1_PAIR             ? ? ? 
hydrog31 hydrog ? ? A A 13 N6 ? ? ? 1_555 A A 44 N1 ? ? B A 13 B A 45 1_555 ? ? ? ? ? ? TYPE_1_PAIR             ? ? ? 
hydrog32 hydrog ? ? A A 14 N6 ? ? ? 1_555 A A 20 N3 ? ? B A 14 B A 21 1_555 ? ? ? ? ? ? 'A-A MISPAIR'           ? ? ? 
hydrog33 hydrog ? ? A G 15 N1 ? ? ? 1_555 A C 47 O2 ? ? B G 15 B C 48 1_555 ? ? ? ? ? ? 'REVERSED WATSON-CRICK' ? ? ? 
hydrog34 hydrog ? ? A G 15 N2 ? ? ? 1_555 A C 47 N3 ? ? B G 15 B C 48 1_555 ? ? ? ? ? ? 'REVERSED WATSON-CRICK' ? ? ? 
hydrog35 hydrog ? ? A G 17 N1 ? ? ? 1_555 A U 54 O2 ? ? B G 18 B U 55 1_555 ? ? ? ? ? ? 'G-U MISPAIR'           ? ? ? 
hydrog36 hydrog ? ? A G 18 N2 ? ? ? 1_555 A U 19 O4 ? ? B G 19 B U 20 1_555 ? ? ? ? ? ? 'G-U MISPAIR'           ? ? ? 
hydrog37 hydrog ? ? A G 18 N1 ? ? ? 1_555 A C 55 N3 ? ? B G 19 B C 56 1_555 ? ? ? ? ? ? WATSON-CRICK            ? ? ? 
hydrog38 hydrog ? ? A G 18 N2 ? ? ? 1_555 A C 55 O2 ? ? B G 19 B C 56 1_555 ? ? ? ? ? ? WATSON-CRICK            ? ? ? 
hydrog39 hydrog ? ? A G 18 O6 ? ? ? 1_555 A C 55 N4 ? ? B G 19 B C 56 1_555 ? ? ? ? ? ? WATSON-CRICK            ? ? ? 
hydrog40 hydrog ? ? A A 25 N6 ? ? ? 1_555 A C 43 O2 ? ? B A 26 B C 44 1_555 ? ? ? ? ? ? 'A-C MISPAIR'           ? ? ? 
hydrog41 hydrog ? ? A C 26 N3 ? ? ? 1_555 A G 42 N1 ? ? B C 27 B G 43 1_555 ? ? ? ? ? ? WATSON-CRICK            ? ? ? 
hydrog42 hydrog ? ? A C 26 N4 ? ? ? 1_555 A G 42 O6 ? ? B C 27 B G 43 1_555 ? ? ? ? ? ? WATSON-CRICK            ? ? ? 
hydrog43 hydrog ? ? A C 26 O2 ? ? ? 1_555 A G 42 N2 ? ? B C 27 B G 43 1_555 ? ? ? ? ? ? WATSON-CRICK            ? ? ? 
hydrog44 hydrog ? ? A C 27 N3 ? ? ? 1_555 A G 41 N1 ? ? B C 28 B G 42 1_555 ? ? ? ? ? ? WATSON-CRICK            ? ? ? 
hydrog45 hydrog ? ? A C 27 N4 ? ? ? 1_555 A G 41 O6 ? ? B C 28 B G 42 1_555 ? ? ? ? ? ? WATSON-CRICK            ? ? ? 
hydrog46 hydrog ? ? A C 27 O2 ? ? ? 1_555 A G 41 N2 ? ? B C 28 B G 42 1_555 ? ? ? ? ? ? WATSON-CRICK            ? ? ? 
hydrog47 hydrog ? ? A G 28 N1 ? ? ? 1_555 A C 40 N3 ? ? B G 29 B C 41 1_555 ? ? ? ? ? ? WATSON-CRICK            ? ? ? 
hydrog48 hydrog ? ? A G 28 N2 ? ? ? 1_555 A C 40 O2 ? ? B G 29 B C 41 1_555 ? ? ? ? ? ? WATSON-CRICK            ? ? ? 
hydrog49 hydrog ? ? A G 28 O6 ? ? ? 1_555 A C 40 N4 ? ? B G 29 B C 41 1_555 ? ? ? ? ? ? WATSON-CRICK            ? ? ? 
hydrog50 hydrog ? ? A G 29 N1 ? ? ? 1_555 A C 39 N3 ? ? B G 30 B C 40 1_555 ? ? ? ? ? ? WATSON-CRICK            ? ? ? 
hydrog51 hydrog ? ? A G 29 N2 ? ? ? 1_555 A C 39 O2 ? ? B G 30 B C 40 1_555 ? ? ? ? ? ? WATSON-CRICK            ? ? ? 
hydrog52 hydrog ? ? A G 29 O6 ? ? ? 1_555 A C 39 N4 ? ? B G 30 B C 40 1_555 ? ? ? ? ? ? WATSON-CRICK            ? ? ? 
hydrog53 hydrog ? ? A A 30 N1 ? ? ? 1_555 A U 38 N3 ? ? B A 31 B U 39 1_555 ? ? ? ? ? ? 'A-U PAIR'              ? ? ? 
hydrog54 hydrog ? ? A U 31 N3 ? ? ? 1_555 A U 37 O4 ? ? B U 32 B U 38 1_555 ? ? ? ? ? ? 'U-U MISPAIR'           ? ? ? 
hydrog55 hydrog ? ? A C 48 N3 ? ? ? 1_555 A G 64 N1 ? ? B C 49 B G 65 1_555 ? ? ? ? ? ? WATSON-CRICK            ? ? ? 
hydrog56 hydrog ? ? A C 48 N4 ? ? ? 1_555 A G 64 O6 ? ? B C 49 B G 65 1_555 ? ? ? ? ? ? WATSON-CRICK            ? ? ? 
hydrog57 hydrog ? ? A C 48 O2 ? ? ? 1_555 A G 64 N2 ? ? B C 49 B G 65 1_555 ? ? ? ? ? ? WATSON-CRICK            ? ? ? 
hydrog58 hydrog ? ? A G 49 N1 ? ? ? 1_555 A C 63 N3 ? ? B G 50 B C 64 1_555 ? ? ? ? ? ? WATSON-CRICK            ? ? ? 
hydrog59 hydrog ? ? A G 49 N2 ? ? ? 1_555 A C 63 O2 ? ? B G 50 B C 64 1_555 ? ? ? ? ? ? WATSON-CRICK            ? ? ? 
hydrog60 hydrog ? ? A G 49 O6 ? ? ? 1_555 A C 63 N4 ? ? B G 50 B C 64 1_555 ? ? ? ? ? ? WATSON-CRICK            ? ? ? 
hydrog61 hydrog ? ? A A 50 N1 ? ? ? 1_555 A U 62 N3 ? ? B A 51 B U 63 1_555 ? ? ? ? ? ? WATSON-CRICK            ? ? ? 
hydrog62 hydrog ? ? A A 50 N6 ? ? ? 1_555 A U 62 O4 ? ? B A 51 B U 63 1_555 ? ? ? ? ? ? WATSON-CRICK            ? ? ? 
hydrog63 hydrog ? ? A G 51 N1 ? ? ? 1_555 A C 61 N3 ? ? B G 52 B C 62 1_555 ? ? ? ? ? ? WATSON-CRICK            ? ? ? 
hydrog64 hydrog ? ? A G 51 N2 ? ? ? 1_555 A C 61 O2 ? ? B G 52 B C 62 1_555 ? ? ? ? ? ? WATSON-CRICK            ? ? ? 
hydrog65 hydrog ? ? A G 51 O6 ? ? ? 1_555 A C 61 N4 ? ? B G 52 B C 62 1_555 ? ? ? ? ? ? WATSON-CRICK            ? ? ? 
hydrog66 hydrog ? ? A G 52 N1 ? ? ? 1_555 A C 60 N3 ? ? B G 53 B C 61 1_555 ? ? ? ? ? ? WATSON-CRICK            ? ? ? 
hydrog67 hydrog ? ? A G 52 N2 ? ? ? 1_555 A C 60 O2 ? ? B G 53 B C 61 1_555 ? ? ? ? ? ? WATSON-CRICK            ? ? ? 
hydrog68 hydrog ? ? A G 52 O6 ? ? ? 1_555 A C 60 N4 ? ? B G 53 B C 61 1_555 ? ? ? ? ? ? WATSON-CRICK            ? ? ? 
hydrog69 hydrog ? ? A U 53 N3 ? ? ? 1_555 A A 57 N7 ? ? B U 54 B A 58 1_555 ? ? ? ? ? ? 'REVERSED HOOGSTEEN'    ? ? ? 
hydrog70 hydrog ? ? A U 53 O2 ? ? ? 1_555 A A 57 N6 ? ? B U 54 B A 58 1_555 ? ? ? ? ? ? 'REVERSED HOOGSTEEN'    ? ? ? 
# 
_struct_conn_type.id          hydrog 
_struct_conn_type.criteria    ? 
_struct_conn_type.reference   ? 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
A ? 2 ? 
B ? 2 ? 
C ? 2 ? 
D ? 2 ? 
E ? 2 ? 
F ? 5 ? 
G ? 2 ? 
H ? 4 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
A 1 2 ? parallel      
B 1 2 ? anti-parallel 
C 1 2 ? anti-parallel 
D 1 2 ? parallel      
E 1 2 ? parallel      
F 1 2 ? anti-parallel 
F 2 3 ? parallel      
F 3 4 ? anti-parallel 
F 4 5 ? anti-parallel 
G 1 2 ? anti-parallel 
H 1 2 ? anti-parallel 
H 2 3 ? parallel      
H 3 4 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
A 1 HIS B 28  ? PHE B 31  ? HIS A 28  PHE A 31  
A 2 GLN B 60  ? LEU B 63  ? GLN A 60  LEU A 63  
B 1 ALA B 119 ? ASP B 122 ? ALA A 119 ASP A 122 
B 2 CYS B 171 ? ALA B 174 ? CYS A 171 ALA A 174 
C 1 TYR B 191 ? ILE B 193 ? TYR A 191 ILE A 193 
C 2 ILE B 207 ? PRO B 209 ? ILE A 207 PRO A 209 
D 1 HIS B 226 ? THR B 230 ? HIS A 226 THR A 230 
D 2 ARG B 254 ? PHE B 258 ? ARG A 254 PHE A 258 
E 1 PRO B 340 ? ALA B 342 ? PRO A 340 ALA A 342 
E 2 PHE B 516 ? PHE B 518 ? PHE A 516 PHE A 518 
F 1 GLU B 384 ? ASP B 388 ? GLU A 384 ASP A 388 
F 2 PRO B 348 ? ILE B 353 ? PRO A 348 ILE A 353 
F 3 THR B 432 ? TYR B 437 ? THR A 432 TYR A 437 
F 4 VAL B 416 ? GLU B 423 ? VAL A 416 GLU A 423 
F 5 GLU B 408 ? ARG B 410 ? GLU A 408 ARG A 410 
G 1 MET B 362 ? PRO B 366 ? MET A 362 PRO A 366 
G 2 SER B 376 ? PRO B 380 ? SER A 376 PRO A 380 
H 1 LEU B 496 ? GLU B 504 ? LEU A 496 GLU A 504 
H 2 ALA B 464 ? TYR B 472 ? ALA A 464 TYR A 472 
H 3 PRO B 536 ? GLY B 543 ? PRO A 536 GLY A 543 
H 4 GLY B 522 ? LEU B 526 ? GLY A 522 LEU A 526 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
A 1 2 O THR B 29  ? O THR A 29  N GLN B 60  ? N GLN A 60  
B 1 2 O TYR B 120 ? O TYR A 120 N ARG B 173 ? N ARG A 173 
C 1 2 O ARG B 192 ? O ARG A 192 N TYR B 208 ? N TYR A 208 
D 1 2 O SER B 227 ? O SER A 227 N ARG B 254 ? N ARG A 254 
E 1 2 O PRO B 340 ? O PRO A 340 N GLN B 517 ? N GLN A 517 
F 1 2 O ILE B 385 ? O ILE A 385 N LEU B 351 ? N LEU A 351 
F 2 3 O LYS B 350 ? O LYS A 350 N ILE B 433 ? N ILE A 433 
F 3 4 O THR B 432 ? O THR A 432 N GLU B 423 ? N GLU A 423 
F 4 5 O ILE B 417 ? O ILE A 417 N VAL B 409 ? N VAL A 409 
G 1 2 O VAL B 363 ? O VAL A 363 N VAL B 379 ? N VAL A 379 
H 1 2 O VAL B 497 ? O VAL A 497 N LEU B 471 ? N LEU A 471 
H 2 3 O GLU B 468 ? O GLU A 468 N PRO B 536 ? N PRO A 536 
H 3 4 O ASN B 539 ? O ASN A 539 N CYS B 525 ? N CYS A 525 
# 
_struct_site.id                   AC1 
_struct_site.pdbx_evidence_code   Software 
_struct_site.pdbx_auth_asym_id    A 
_struct_site.pdbx_auth_comp_id    ATP 
_struct_site.pdbx_auth_seq_id     999 
_struct_site.pdbx_auth_ins_code   ? 
_struct_site.pdbx_num_residues    11 
_struct_site.details              'BINDING SITE FOR RESIDUE ATP A 999' 
# 
loop_
_struct_site_gen.id 
_struct_site_gen.site_id 
_struct_site_gen.pdbx_num_res 
_struct_site_gen.label_comp_id 
_struct_site_gen.label_asym_id 
_struct_site_gen.label_seq_id 
_struct_site_gen.pdbx_auth_ins_code 
_struct_site_gen.auth_comp_id 
_struct_site_gen.auth_asym_id 
_struct_site_gen.auth_seq_id 
_struct_site_gen.label_atom_id 
_struct_site_gen.label_alt_id 
_struct_site_gen.symmetry 
_struct_site_gen.details 
1  AC1 11 PRO B 32  ? PRO A 32  . ? 1_555 ? 
2  AC1 11 GLU B 34  ? GLU A 34  . ? 1_555 ? 
3  AC1 11 ASN B 36  ? ASN A 36  . ? 1_555 ? 
4  AC1 11 GLY B 42  ? GLY A 42  . ? 1_555 ? 
5  AC1 11 HIS B 43  ? HIS A 43  . ? 1_555 ? 
6  AC1 11 CYS B 229 ? CYS A 229 . ? 1_555 ? 
7  AC1 11 THR B 230 ? THR A 230 . ? 1_555 ? 
8  AC1 11 ARG B 260 ? ARG A 260 . ? 1_555 ? 
9  AC1 11 LEU B 261 ? LEU A 261 . ? 1_555 ? 
10 AC1 11 LYS B 270 ? LYS A 270 . ? 1_555 ? 
11 AC1 11 A   A 75  ? A   B 76  . ? 1_555 ? 
# 
_database_PDB_matrix.entry_id          1QRU 
_database_PDB_matrix.origx[1][1]       1.000000 
_database_PDB_matrix.origx[1][2]       0.000000 
_database_PDB_matrix.origx[1][3]       0.000000 
_database_PDB_matrix.origx[2][1]       0.000000 
_database_PDB_matrix.origx[2][2]       1.000000 
_database_PDB_matrix.origx[2][3]       0.000000 
_database_PDB_matrix.origx[3][1]       0.000000 
_database_PDB_matrix.origx[3][2]       0.000000 
_database_PDB_matrix.origx[3][3]       1.000000 
_database_PDB_matrix.origx_vector[1]   0.00000 
_database_PDB_matrix.origx_vector[2]   0.00000 
_database_PDB_matrix.origx_vector[3]   0.00000 
# 
_atom_sites.entry_id                    1QRU 
_atom_sites.fract_transf_matrix[1][1]   0.004132 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   0.010672 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   0.008658 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
# 
loop_
_atom_type.symbol 
C 
H 
N 
O 
P 
S 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    P P      . G   A 1 2   ? 41.639 45.910  40.890 1.00 63.85 ? 2   G   B P      1 
ATOM   2    O OP1    . G   A 1 2   ? 40.359 46.478  41.398 1.00 70.17 ? 2   G   B OP1    1 
ATOM   3    O OP2    . G   A 1 2   ? 42.922 46.340  41.503 1.00 70.88 ? 2   G   B OP2    1 
ATOM   4    O "O5'"  . G   A 1 2   ? 41.712 46.251  39.339 1.00 63.72 ? 2   G   B "O5'"  1 
ATOM   5    C "C5'"  . G   A 1 2   ? 41.762 47.602  38.913 1.00 49.43 ? 2   G   B "C5'"  1 
ATOM   6    C "C4'"  . G   A 1 2   ? 42.358 47.696  37.538 1.00 38.35 ? 2   G   B "C4'"  1 
ATOM   7    O "O4'"  . G   A 1 2   ? 43.586 46.925  37.511 1.00 35.04 ? 2   G   B "O4'"  1 
ATOM   8    C "C3'"  . G   A 1 2   ? 41.558 47.117  36.394 1.00 34.26 ? 2   G   B "C3'"  1 
ATOM   9    O "O3'"  . G   A 1 2   ? 40.600 48.057  35.949 1.00 30.02 ? 2   G   B "O3'"  1 
ATOM   10   C "C2'"  . G   A 1 2   ? 42.648 46.942  35.361 1.00 34.76 ? 2   G   B "C2'"  1 
ATOM   11   O "O2'"  . G   A 1 2   ? 43.066 48.189  34.842 1.00 33.60 ? 2   G   B "O2'"  1 
ATOM   12   C "C1'"  . G   A 1 2   ? 43.759 46.362  36.234 1.00 33.53 ? 2   G   B "C1'"  1 
ATOM   13   N N9     . G   A 1 2   ? 43.575 44.931  36.360 1.00 32.02 ? 2   G   B N9     1 
ATOM   14   C C8     . G   A 1 2   ? 43.225 44.239  37.489 1.00 31.05 ? 2   G   B C8     1 
ATOM   15   N N7     . G   A 1 2   ? 43.130 42.953  37.287 1.00 30.29 ? 2   G   B N7     1 
ATOM   16   C C5     . G   A 1 2   ? 43.441 42.794  35.942 1.00 30.82 ? 2   G   B C5     1 
ATOM   17   C C6     . G   A 1 2   ? 43.509 41.625  35.142 1.00 32.63 ? 2   G   B C6     1 
ATOM   18   O O6     . G   A 1 2   ? 43.315 40.451  35.469 1.00 36.02 ? 2   G   B O6     1 
ATOM   19   N N1     . G   A 1 2   ? 43.852 41.916  33.834 1.00 32.36 ? 2   G   B N1     1 
ATOM   20   C C2     . G   A 1 2   ? 44.104 43.170  33.358 1.00 33.44 ? 2   G   B C2     1 
ATOM   21   N N2     . G   A 1 2   ? 44.433 43.253  32.064 1.00 34.30 ? 2   G   B N2     1 
ATOM   22   N N3     . G   A 1 2   ? 44.045 44.266  34.085 1.00 34.48 ? 2   G   B N3     1 
ATOM   23   C C4     . G   A 1 2   ? 43.711 44.006  35.360 1.00 32.20 ? 2   G   B C4     1 
ATOM   24   H "HO2'" . G   A 1 2   ? 43.755 48.017  34.201 1.00 20.00 ? 2   G   B "HO2'" 1 
ATOM   25   H H1     . G   A 1 2   ? 43.938 41.148  33.191 1.00 20.00 ? 2   G   B H1     1 
ATOM   26   H H21    . G   A 1 2   ? 44.626 44.158  31.657 1.00 20.00 ? 2   G   B H21    1 
ATOM   27   H H22    . G   A 1 2   ? 44.487 42.419  31.492 1.00 20.00 ? 2   G   B H22    1 
ATOM   28   P P      . G   A 1 3   ? 39.109 47.572  35.610 1.00 30.25 ? 3   G   B P      1 
ATOM   29   O OP1    . G   A 1 3   ? 38.278 48.807  35.508 1.00 27.56 ? 3   G   B OP1    1 
ATOM   30   O OP2    . G   A 1 3   ? 38.692 46.480  36.532 1.00 27.87 ? 3   G   B OP2    1 
ATOM   31   O "O5'"  . G   A 1 3   ? 39.247 46.938  34.154 1.00 27.50 ? 3   G   B "O5'"  1 
ATOM   32   C "C5'"  . G   A 1 3   ? 39.730 47.727  33.080 1.00 24.34 ? 3   G   B "C5'"  1 
ATOM   33   C "C4'"  . G   A 1 3   ? 40.193 46.841  31.952 1.00 18.93 ? 3   G   B "C4'"  1 
ATOM   34   O "O4'"  . G   A 1 3   ? 41.255 45.964  32.410 1.00 16.33 ? 3   G   B "O4'"  1 
ATOM   35   C "C3'"  . G   A 1 3   ? 39.196 45.873  31.373 1.00 17.05 ? 3   G   B "C3'"  1 
ATOM   36   O "O3'"  . G   A 1 3   ? 38.294 46.547  30.512 1.00 18.62 ? 3   G   B "O3'"  1 
ATOM   37   C "C2'"  . G   A 1 3   ? 40.133 44.949  30.614 1.00 16.49 ? 3   G   B "C2'"  1 
ATOM   38   O "O2'"  . G   A 1 3   ? 40.672 45.570  29.458 1.00 17.87 ? 3   G   B "O2'"  1 
ATOM   39   C "C1'"  . G   A 1 3   ? 41.265 44.795  31.628 1.00 13.88 ? 3   G   B "C1'"  1 
ATOM   40   N N9     . G   A 1 3   ? 41.048 43.640  32.490 1.00 11.93 ? 3   G   B N9     1 
ATOM   41   C C8     . G   A 1 3   ? 40.690 43.641  33.817 1.00 7.83  ? 3   G   B C8     1 
ATOM   42   N N7     . G   A 1 3   ? 40.507 42.433  34.290 1.00 8.02  ? 3   G   B N7     1 
ATOM   43   C C5     . G   A 1 3   ? 40.773 41.590  33.222 1.00 8.07  ? 3   G   B C5     1 
ATOM   44   C C6     . G   A 1 3   ? 40.731 40.177  33.137 1.00 8.51  ? 3   G   B C6     1 
ATOM   45   O O6     . G   A 1 3   ? 40.455 39.351  34.020 1.00 8.43  ? 3   G   B O6     1 
ATOM   46   N N1     . G   A 1 3   ? 41.074 39.743  31.862 1.00 8.19  ? 3   G   B N1     1 
ATOM   47   C C2     . G   A 1 3   ? 41.429 40.558  30.825 1.00 7.82  ? 3   G   B C2     1 
ATOM   48   N N2     . G   A 1 3   ? 41.761 39.950  29.703 1.00 9.11  ? 3   G   B N2     1 
ATOM   49   N N3     . G   A 1 3   ? 41.469 41.874  30.881 1.00 9.43  ? 3   G   B N3     1 
ATOM   50   C C4     . G   A 1 3   ? 41.126 42.320  32.114 1.00 11.25 ? 3   G   B C4     1 
ATOM   51   H "HO2'" . G   A 1 3   ? 41.229 44.917  29.038 1.00 20.00 ? 3   G   B "HO2'" 1 
ATOM   52   H H1     . G   A 1 3   ? 41.052 38.743  31.695 1.00 20.00 ? 3   G   B H1     1 
ATOM   53   H H21    . G   A 1 3   ? 42.017 40.490  28.894 1.00 20.00 ? 3   G   B H21    1 
ATOM   54   H H22    . G   A 1 3   ? 41.733 38.942  29.638 1.00 20.00 ? 3   G   B H22    1 
ATOM   55   P P      . G   A 1 4   ? 36.795 46.011  30.371 1.00 20.40 ? 4   G   B P      1 
ATOM   56   O OP1    . G   A 1 4   ? 35.952 47.039  29.716 1.00 18.85 ? 4   G   B OP1    1 
ATOM   57   O OP2    . G   A 1 4   ? 36.394 45.483  31.693 1.00 20.86 ? 4   G   B OP2    1 
ATOM   58   O "O5'"  . G   A 1 4   ? 36.957 44.758  29.399 1.00 18.45 ? 4   G   B "O5'"  1 
ATOM   59   C "C5'"  . G   A 1 4   ? 37.709 44.875  28.195 1.00 19.16 ? 4   G   B "C5'"  1 
ATOM   60   C "C4'"  . G   A 1 4   ? 37.931 43.511  27.592 1.00 15.97 ? 4   G   B "C4'"  1 
ATOM   61   O "O4'"  . G   A 1 4   ? 38.847 42.735  28.412 1.00 15.31 ? 4   G   B "O4'"  1 
ATOM   62   C "C3'"  . G   A 1 4   ? 36.698 42.645  27.556 1.00 13.65 ? 4   G   B "C3'"  1 
ATOM   63   O "O3'"  . G   A 1 4   ? 35.863 43.004  26.472 1.00 11.60 ? 4   G   B "O3'"  1 
ATOM   64   C "C2'"  . G   A 1 4   ? 37.303 41.257  27.412 1.00 12.56 ? 4   G   B "C2'"  1 
ATOM   65   O "O2'"  . G   A 1 4   ? 37.752 41.019  26.104 1.00 11.61 ? 4   G   B "O2'"  1 
ATOM   66   C "C1'"  . G   A 1 4   ? 38.501 41.362  28.346 1.00 10.57 ? 4   G   B "C1'"  1 
ATOM   67   N N9     . G   A 1 4   ? 38.204 40.922  29.702 1.00 10.39 ? 4   G   B N9     1 
ATOM   68   C C8     . G   A 1 4   ? 37.860 41.722  30.760 1.00 10.04 ? 4   G   B C8     1 
ATOM   69   N N7     . G   A 1 4   ? 37.628 41.041  31.848 1.00 12.92 ? 4   G   B N7     1 
ATOM   70   C C5     . G   A 1 4   ? 37.824 39.719  31.488 1.00 12.85 ? 4   G   B C5     1 
ATOM   71   C C6     . G   A 1 4   ? 37.687 38.520  32.245 1.00 13.65 ? 4   G   B C6     1 
ATOM   72   O O6     . G   A 1 4   ? 37.321 38.386  33.428 1.00 12.92 ? 4   G   B O6     1 
ATOM   73   N N1     . G   A 1 4   ? 38.005 37.402  31.494 1.00 13.02 ? 4   G   B N1     1 
ATOM   74   C C2     . G   A 1 4   ? 38.389 37.428  30.177 1.00 12.18 ? 4   G   B C2     1 
ATOM   75   N N2     . G   A 1 4   ? 38.666 36.243  29.621 1.00 15.55 ? 4   G   B N2     1 
ATOM   76   N N3     . G   A 1 4   ? 38.495 38.528  29.448 1.00 15.70 ? 4   G   B N3     1 
ATOM   77   C C4     . G   A 1 4   ? 38.200 39.628  30.167 1.00 13.42 ? 4   G   B C4     1 
ATOM   78   H "HO2'" . G   A 1 4   ? 38.134 40.144  26.082 1.00 20.00 ? 4   G   B "HO2'" 1 
ATOM   79   H H1     . G   A 1 4   ? 37.954 36.502  31.947 1.00 20.00 ? 4   G   B H1     1 
ATOM   80   H H21    . G   A 1 4   ? 38.916 36.199  28.647 1.00 20.00 ? 4   G   B H21    1 
ATOM   81   H H22    . G   A 1 4   ? 38.564 35.387  30.150 1.00 20.00 ? 4   G   B H22    1 
ATOM   82   P P      . G   A 1 5   ? 34.374 42.410  26.405 1.00 9.43  ? 5   G   B P      1 
ATOM   83   O OP1    . G   A 1 5   ? 33.916 42.597  25.000 1.00 12.84 ? 5   G   B OP1    1 
ATOM   84   O OP2    . G   A 1 5   ? 33.539 42.921  27.543 1.00 7.00  ? 5   G   B OP2    1 
ATOM   85   O "O5'"  . G   A 1 5   ? 34.595 40.862  26.643 1.00 6.36  ? 5   G   B "O5'"  1 
ATOM   86   C "C5'"  . G   A 1 5   ? 33.511 40.028  26.962 1.00 4.33  ? 5   G   B "C5'"  1 
ATOM   87   C "C4'"  . G   A 1 5   ? 33.960 38.606  26.970 1.00 3.79  ? 5   G   B "C4'"  1 
ATOM   88   O "O4'"  . G   A 1 5   ? 35.093 38.450  27.854 1.00 4.97  ? 5   G   B "O4'"  1 
ATOM   89   C "C3'"  . G   A 1 5   ? 32.921 37.682  27.528 1.00 3.67  ? 5   G   B "C3'"  1 
ATOM   90   O "O3'"  . G   A 1 5   ? 32.009 37.360  26.503 1.00 6.04  ? 5   G   B "O3'"  1 
ATOM   91   C "C2'"  . G   A 1 5   ? 33.772 36.520  28.000 1.00 3.66  ? 5   G   B "C2'"  1 
ATOM   92   O "O2'"  . G   A 1 5   ? 34.280 35.763  26.931 1.00 3.85  ? 5   G   B "O2'"  1 
ATOM   93   C "C1'"  . G   A 1 5   ? 34.966 37.263  28.598 1.00 6.01  ? 5   G   B "C1'"  1 
ATOM   94   N N9     . G   A 1 5   ? 34.774 37.593  30.012 1.00 7.05  ? 5   G   B N9     1 
ATOM   95   C C8     . G   A 1 5   ? 34.607 38.828  30.583 1.00 4.94  ? 5   G   B C8     1 
ATOM   96   N N7     . G   A 1 5   ? 34.441 38.768  31.882 1.00 7.09  ? 5   G   B N7     1 
ATOM   97   C C5     . G   A 1 5   ? 34.526 37.418  32.177 1.00 8.77  ? 5   G   B C5     1 
ATOM   98   C C6     . G   A 1 5   ? 34.454 36.728  33.428 1.00 10.13 ? 5   G   B C6     1 
ATOM   99   O O6     . G   A 1 5   ? 34.334 37.195  34.576 1.00 10.22 ? 5   G   B O6     1 
ATOM   100  N N1     . G   A 1 5   ? 34.563 35.349  33.257 1.00 9.67  ? 5   G   B N1     1 
ATOM   101  C C2     . G   A 1 5   ? 34.745 34.721  32.053 1.00 10.60 ? 5   G   B C2     1 
ATOM   102  N N2     . G   A 1 5   ? 34.832 33.391  32.069 1.00 10.18 ? 5   G   B N2     1 
ATOM   103  N N3     . G   A 1 5   ? 34.845 35.347  30.904 1.00 8.46  ? 5   G   B N3     1 
ATOM   104  C C4     . G   A 1 5   ? 34.719 36.683  31.036 1.00 7.58  ? 5   G   B C4     1 
ATOM   105  H "HO2'" . G   A 1 5   ? 34.752 35.030  27.331 1.00 20.00 ? 5   G   B "HO2'" 1 
ATOM   106  H H1     . G   A 1 5   ? 34.474 34.772  34.077 1.00 20.00 ? 5   G   B H1     1 
ATOM   107  H H21    . G   A 1 5   ? 34.942 32.892  31.199 1.00 20.00 ? 5   G   B H21    1 
ATOM   108  H H22    . G   A 1 5   ? 34.736 32.873  32.935 1.00 20.00 ? 5   G   B H22    1 
ATOM   109  P P      . U   A 1 6   ? 30.457 37.288  26.854 1.00 4.14  ? 6   U   B P      1 
ATOM   110  O OP1    . U   A 1 6   ? 29.655 37.080  25.609 1.00 9.06  ? 6   U   B OP1    1 
ATOM   111  O OP2    . U   A 1 6   ? 30.170 38.465  27.716 1.00 8.57  ? 6   U   B OP2    1 
ATOM   112  O "O5'"  . U   A 1 6   ? 30.415 35.958  27.724 1.00 3.24  ? 6   U   B "O5'"  1 
ATOM   113  C "C5'"  . U   A 1 6   ? 30.872 34.757  27.156 1.00 2.01  ? 6   U   B "C5'"  1 
ATOM   114  C "C4'"  . U   A 1 6   ? 30.765 33.643  28.144 1.00 2.01  ? 6   U   B "C4'"  1 
ATOM   115  O "O4'"  . U   A 1 6   ? 31.703 33.887  29.197 1.00 2.00  ? 6   U   B "O4'"  1 
ATOM   116  C "C3'"  . U   A 1 6   ? 29.444 33.514  28.883 1.00 2.00  ? 6   U   B "C3'"  1 
ATOM   117  O "O3'"  . U   A 1 6   ? 28.484 32.792  28.108 1.00 5.10  ? 6   U   B "O3'"  1 
ATOM   118  C "C2'"  . U   A 1 6   ? 29.870 32.699  30.080 1.00 2.00  ? 6   U   B "C2'"  1 
ATOM   119  O "O2'"  . U   A 1 6   ? 30.069 31.349  29.708 1.00 2.00  ? 6   U   B "O2'"  1 
ATOM   120  C "C1'"  . U   A 1 6   ? 31.215 33.337  30.389 1.00 2.01  ? 6   U   B "C1'"  1 
ATOM   121  N N1     . U   A 1 6   ? 31.121 34.418  31.366 1.00 2.00  ? 6   U   B N1     1 
ATOM   122  C C2     . U   A 1 6   ? 31.215 34.085  32.689 1.00 2.63  ? 6   U   B C2     1 
ATOM   123  O O2     . U   A 1 6   ? 31.359 32.932  33.069 1.00 4.48  ? 6   U   B O2     1 
ATOM   124  N N3     . U   A 1 6   ? 31.126 35.151  33.555 1.00 4.11  ? 6   U   B N3     1 
ATOM   125  C C4     . U   A 1 6   ? 30.969 36.477  33.218 1.00 4.38  ? 6   U   B C4     1 
ATOM   126  O O4     . U   A 1 6   ? 30.930 37.336  34.108 1.00 10.68 ? 6   U   B O4     1 
ATOM   127  C C5     . U   A 1 6   ? 30.871 36.721  31.818 1.00 2.00  ? 6   U   B C5     1 
ATOM   128  C C6     . U   A 1 6   ? 30.946 35.706  30.966 1.00 2.69  ? 6   U   B C6     1 
ATOM   129  H "HO2'" . U   A 1 6   ? 30.356 30.868  30.482 1.00 20.00 ? 6   U   B "HO2'" 1 
ATOM   130  H H3     . U   A 1 6   ? 31.156 34.946  34.539 1.00 20.00 ? 6   U   B H3     1 
ATOM   131  P P      . A   A 1 7   ? 27.032 32.457  28.728 1.00 4.43  ? 7   A   B P      1 
ATOM   132  O OP1    . A   A 1 7   ? 26.222 31.928  27.580 1.00 4.48  ? 7   A   B OP1    1 
ATOM   133  O OP2    . A   A 1 7   ? 26.552 33.655  29.491 1.00 4.02  ? 7   A   B OP2    1 
ATOM   134  O "O5'"  . A   A 1 7   ? 27.349 31.295  29.790 1.00 4.00  ? 7   A   B "O5'"  1 
ATOM   135  C "C5'"  . A   A 1 7   ? 26.308 30.568  30.451 1.00 8.20  ? 7   A   B "C5'"  1 
ATOM   136  C "C4'"  . A   A 1 7   ? 26.729 30.251  31.877 1.00 12.18 ? 7   A   B "C4'"  1 
ATOM   137  O "O4'"  . A   A 1 7   ? 27.502 31.347  32.367 1.00 13.70 ? 7   A   B "O4'"  1 
ATOM   138  C "C3'"  . A   A 1 7   ? 25.566 30.015  32.836 1.00 12.09 ? 7   A   B "C3'"  1 
ATOM   139  O "O3'"  . A   A 1 7   ? 25.650 28.709  33.415 1.00 12.04 ? 7   A   B "O3'"  1 
ATOM   140  C "C2'"  . A   A 1 7   ? 25.828 30.942  34.025 1.00 16.35 ? 7   A   B "C2'"  1 
ATOM   141  O "O2'"  . A   A 1 7   ? 25.872 30.266  35.261 1.00 15.93 ? 7   A   B "O2'"  1 
ATOM   142  C "C1'"  . A   A 1 7   ? 27.204 31.545  33.702 1.00 17.55 ? 7   A   B "C1'"  1 
ATOM   143  N N9     . A   A 1 7   ? 27.395 32.942  34.014 1.00 20.39 ? 7   A   B N9     1 
ATOM   144  C C8     . A   A 1 7   ? 27.344 34.037  33.190 1.00 23.78 ? 7   A   B C8     1 
ATOM   145  N N7     . A   A 1 7   ? 27.629 35.161  33.802 1.00 25.74 ? 7   A   B N7     1 
ATOM   146  C C5     . A   A 1 7   ? 27.880 34.775  35.109 1.00 24.96 ? 7   A   B C5     1 
ATOM   147  C C6     . A   A 1 7   ? 28.253 35.484  36.244 1.00 25.16 ? 7   A   B C6     1 
ATOM   148  N N6     . A   A 1 7   ? 28.462 36.800  36.242 1.00 24.52 ? 7   A   B N6     1 
ATOM   149  N N1     . A   A 1 7   ? 28.414 34.796  37.392 1.00 26.27 ? 7   A   B N1     1 
ATOM   150  C C2     . A   A 1 7   ? 28.208 33.471  37.382 1.00 25.37 ? 7   A   B C2     1 
ATOM   151  N N3     . A   A 1 7   ? 27.867 32.689  36.377 1.00 24.47 ? 7   A   B N3     1 
ATOM   152  C C4     . A   A 1 7   ? 27.717 33.410  35.256 1.00 22.97 ? 7   A   B C4     1 
ATOM   153  H "HO2'" . A   A 1 7   ? 26.034 30.927  35.934 1.00 20.00 ? 7   A   B "HO2'" 1 
ATOM   154  H H61    . A   A 1 7   ? 28.320 37.322  35.394 1.00 20.00 ? 7   A   B H61    1 
ATOM   155  H H62    . A   A 1 7   ? 28.715 37.282  37.098 1.00 20.00 ? 7   A   B H62    1 
ATOM   156  P P      . U   A 1 8   ? 25.688 27.388  32.503 1.00 12.29 ? 8   U   B P      1 
ATOM   157  O OP1    . U   A 1 8   ? 26.339 26.298  33.280 1.00 12.44 ? 8   U   B OP1    1 
ATOM   158  O OP2    . U   A 1 8   ? 26.228 27.737  31.181 1.00 15.69 ? 8   U   B OP2    1 
ATOM   159  O "O5'"  . U   A 1 8   ? 24.147 26.999  32.351 1.00 16.99 ? 8   U   B "O5'"  1 
ATOM   160  C "C5'"  . U   A 1 8   ? 23.244 27.211  33.430 1.00 15.12 ? 8   U   B "C5'"  1 
ATOM   161  C "C4'"  . U   A 1 8   ? 21.886 26.660  33.104 1.00 14.13 ? 8   U   B "C4'"  1 
ATOM   162  O "O4'"  . U   A 1 8   ? 21.312 27.469  32.055 1.00 14.14 ? 8   U   B "O4'"  1 
ATOM   163  C "C3'"  . U   A 1 8   ? 21.841 25.247  32.533 1.00 15.98 ? 8   U   B "C3'"  1 
ATOM   164  O "O3'"  . U   A 1 8   ? 21.836 24.258  33.549 1.00 20.00 ? 8   U   B "O3'"  1 
ATOM   165  C "C2'"  . U   A 1 8   ? 20.499 25.255  31.837 1.00 13.03 ? 8   U   B "C2'"  1 
ATOM   166  O "O2'"  . U   A 1 8   ? 19.461 25.142  32.787 1.00 14.06 ? 8   U   B "O2'"  1 
ATOM   167  C "C1'"  . U   A 1 8   ? 20.506 26.649  31.225 1.00 13.94 ? 8   U   B "C1'"  1 
ATOM   168  N N1     . U   A 1 8   ? 21.081 26.625  29.874 1.00 15.73 ? 8   U   B N1     1 
ATOM   169  C C2     . U   A 1 8   ? 20.293 26.167  28.876 1.00 15.94 ? 8   U   B C2     1 
ATOM   170  O O2     . U   A 1 8   ? 19.133 25.796  29.059 1.00 15.33 ? 8   U   B O2     1 
ATOM   171  N N3     . U   A 1 8   ? 20.892 26.153  27.627 1.00 16.37 ? 8   U   B N3     1 
ATOM   172  C C4     . U   A 1 8   ? 22.171 26.555  27.299 1.00 14.23 ? 8   U   B C4     1 
ATOM   173  O O4     . U   A 1 8   ? 22.544 26.547  26.094 1.00 14.70 ? 8   U   B O4     1 
ATOM   174  C C5     . U   A 1 8   ? 22.925 27.021  28.407 1.00 13.86 ? 8   U   B C5     1 
ATOM   175  C C6     . U   A 1 8   ? 22.369 27.043  29.633 1.00 11.36 ? 8   U   B C6     1 
ATOM   176  H "HO2'" . U   A 1 8   ? 18.626 25.180  32.316 1.00 20.00 ? 8   U   B "HO2'" 1 
ATOM   177  H H3     . U   A 1 8   ? 20.341 25.829  26.881 1.00 20.00 ? 8   U   B H3     1 
ATOM   178  P P      . C   A 1 9   ? 22.754 22.943  33.379 1.00 23.82 ? 9   C   B P      1 
ATOM   179  O OP1    . C   A 1 9   ? 23.931 23.124  34.270 1.00 21.50 ? 9   C   B OP1    1 
ATOM   180  O OP2    . C   A 1 9   ? 22.948 22.665  31.916 1.00 19.73 ? 9   C   B OP2    1 
ATOM   181  O "O5'"  . C   A 1 9   ? 21.838 21.780  33.980 1.00 28.06 ? 9   C   B "O5'"  1 
ATOM   182  C "C5'"  . C   A 1 9   ? 22.282 20.921  35.047 1.00 34.03 ? 9   C   B "C5'"  1 
ATOM   183  C "C4'"  . C   A 1 9   ? 21.635 19.564  34.870 1.00 38.35 ? 9   C   B "C4'"  1 
ATOM   184  O "O4'"  . C   A 1 9   ? 20.578 19.733  33.913 1.00 42.24 ? 9   C   B "O4'"  1 
ATOM   185  C "C3'"  . C   A 1 9   ? 22.572 18.493  34.314 1.00 39.81 ? 9   C   B "C3'"  1 
ATOM   186  O "O3'"  . C   A 1 9   ? 22.728 17.444  35.271 1.00 34.02 ? 9   C   B "O3'"  1 
ATOM   187  C "C2'"  . C   A 1 9   ? 21.826 17.851  33.143 1.00 43.87 ? 9   C   B "C2'"  1 
ATOM   188  O "O2'"  . C   A 1 9   ? 21.574 16.477  33.269 1.00 43.41 ? 9   C   B "O2'"  1 
ATOM   189  C "C1'"  . C   A 1 9   ? 20.491 18.587  33.127 1.00 47.32 ? 9   C   B "C1'"  1 
ATOM   190  N N1     . C   A 1 9   ? 19.986 18.932  31.806 1.00 54.53 ? 9   C   B N1     1 
ATOM   191  C C2     . C   A 1 9   ? 18.721 18.465  31.465 1.00 55.64 ? 9   C   B C2     1 
ATOM   192  O O2     . C   A 1 9   ? 18.071 17.837  32.315 1.00 56.55 ? 9   C   B O2     1 
ATOM   193  N N3     . C   A 1 9   ? 18.233 18.713  30.236 1.00 57.21 ? 9   C   B N3     1 
ATOM   194  C C4     . C   A 1 9   ? 18.954 19.408  29.365 1.00 59.00 ? 9   C   B C4     1 
ATOM   195  N N4     . C   A 1 9   ? 18.440 19.601  28.153 1.00 61.35 ? 9   C   B N4     1 
ATOM   196  C C5     . C   A 1 9   ? 20.245 19.932  29.697 1.00 60.46 ? 9   C   B C5     1 
ATOM   197  C C6     . C   A 1 9   ? 20.717 19.667  30.920 1.00 60.52 ? 9   C   B C6     1 
ATOM   198  H "HO2'" . C   A 1 9   ? 21.099 16.214  32.483 1.00 20.00 ? 9   C   B "HO2'" 1 
ATOM   199  H H41    . C   A 1 9   ? 18.972 20.095  27.453 1.00 20.00 ? 9   C   B H41    1 
ATOM   200  H H42    . C   A 1 9   ? 17.538 19.210  27.925 1.00 20.00 ? 9   C   B H42    1 
ATOM   201  P P      . G   A 1 10  ? 23.458 17.714  36.667 1.00 32.42 ? 10  G   B P      1 
ATOM   202  O OP1    . G   A 1 10  ? 23.027 16.635  37.604 1.00 34.89 ? 10  G   B OP1    1 
ATOM   203  O OP2    . G   A 1 10  ? 23.268 19.141  37.058 1.00 34.34 ? 10  G   B OP2    1 
ATOM   204  O "O5'"  . G   A 1 10  ? 24.990 17.506  36.290 1.00 33.75 ? 10  G   B "O5'"  1 
ATOM   205  C "C5'"  . G   A 1 10  ? 25.866 16.755  37.115 1.00 30.44 ? 10  G   B "C5'"  1 
ATOM   206  C "C4'"  . G   A 1 10  ? 26.737 15.881  36.257 1.00 24.82 ? 10  G   B "C4'"  1 
ATOM   207  O "O4'"  . G   A 1 10  ? 25.979 14.731  35.816 1.00 23.82 ? 10  G   B "O4'"  1 
ATOM   208  C "C3'"  . G   A 1 10  ? 27.179 16.524  34.962 1.00 25.73 ? 10  G   B "C3'"  1 
ATOM   209  O "O3'"  . G   A 1 10  ? 28.315 17.329  35.179 1.00 26.80 ? 10  G   B "O3'"  1 
ATOM   210  C "C2'"  . G   A 1 10  ? 27.502 15.321  34.090 1.00 23.07 ? 10  G   B "C2'"  1 
ATOM   211  O "O2'"  . G   A 1 10  ? 28.771 14.765  34.373 1.00 24.92 ? 10  G   B "O2'"  1 
ATOM   212  C "C1'"  . G   A 1 10  ? 26.408 14.345  34.529 1.00 22.60 ? 10  G   B "C1'"  1 
ATOM   213  N N9     . G   A 1 10  ? 25.253 14.370  33.654 1.00 17.18 ? 10  G   B N9     1 
ATOM   214  C C8     . G   A 1 10  ? 23.967 14.672  34.032 1.00 14.50 ? 10  G   B C8     1 
ATOM   215  N N7     . G   A 1 10  ? 23.123 14.619  33.034 1.00 15.89 ? 10  G   B N7     1 
ATOM   216  C C5     . G   A 1 10  ? 23.896 14.272  31.946 1.00 15.13 ? 10  G   B C5     1 
ATOM   217  C C6     . G   A 1 10  ? 23.524 14.083  30.615 1.00 14.48 ? 10  G   B C6     1 
ATOM   218  O O6     . G   A 1 10  ? 22.378 14.163  30.131 1.00 14.26 ? 10  G   B O6     1 
ATOM   219  N N1     . G   A 1 10  ? 24.628 13.755  29.809 1.00 12.97 ? 10  G   B N1     1 
ATOM   220  C C2     . G   A 1 10  ? 25.921 13.614  30.267 1.00 16.21 ? 10  G   B C2     1 
ATOM   221  N N2     . G   A 1 10  ? 26.864 13.312  29.352 1.00 15.70 ? 10  G   B N2     1 
ATOM   222  N N3     . G   A 1 10  ? 26.277 13.767  31.535 1.00 15.92 ? 10  G   B N3     1 
ATOM   223  C C4     . G   A 1 10  ? 25.214 14.104  32.312 1.00 16.55 ? 10  G   B C4     1 
ATOM   224  H "HO2'" . G   A 1 10  ? 28.919 14.014  33.801 1.00 20.00 ? 10  G   B "HO2'" 1 
ATOM   225  H H1     . G   A 1 10  ? 24.471 13.592  28.826 1.00 20.00 ? 10  G   B H1     1 
ATOM   226  H H21    . G   A 1 10  ? 27.832 13.222  29.633 1.00 20.00 ? 10  G   B H21    1 
ATOM   227  H H22    . G   A 1 10  ? 26.619 13.190  28.380 1.00 20.00 ? 10  G   B H22    1 
ATOM   228  P P      . C   A 1 11  ? 28.521 18.648  34.307 1.00 24.81 ? 11  C   B P      1 
ATOM   229  O OP1    . C   A 1 11  ? 29.672 19.391  34.868 1.00 25.89 ? 11  C   B OP1    1 
ATOM   230  O OP2    . C   A 1 11  ? 27.186 19.306  34.227 1.00 24.88 ? 11  C   B OP2    1 
ATOM   231  O "O5'"  . C   A 1 11  ? 28.903 18.089  32.860 1.00 23.03 ? 11  C   B "O5'"  1 
ATOM   232  C "C5'"  . C   A 1 11  ? 30.254 17.799  32.523 1.00 22.05 ? 11  C   B "C5'"  1 
ATOM   233  C "C4'"  . C   A 1 11  ? 30.337 17.351  31.076 1.00 18.59 ? 11  C   B "C4'"  1 
ATOM   234  O "O4'"  . C   A 1 11  ? 29.433 16.234  30.847 1.00 19.68 ? 11  C   B "O4'"  1 
ATOM   235  C "C3'"  . C   A 1 11  ? 29.896 18.364  30.051 1.00 14.93 ? 11  C   B "C3'"  1 
ATOM   236  O "O3'"  . C   A 1 11  ? 30.934 19.253  29.794 1.00 14.59 ? 11  C   B "O3'"  1 
ATOM   237  C "C2'"  . C   A 1 11  ? 29.614 17.486  28.854 1.00 16.72 ? 11  C   B "C2'"  1 
ATOM   238  O "O2'"  . C   A 1 11  ? 30.783 17.020  28.213 1.00 17.32 ? 11  C   B "O2'"  1 
ATOM   239  C "C1'"  . C   A 1 11  ? 28.910 16.316  29.530 1.00 16.48 ? 11  C   B "C1'"  1 
ATOM   240  N N1     . C   A 1 11  ? 27.473 16.573  29.618 1.00 13.72 ? 11  C   B N1     1 
ATOM   241  C C2     . C   A 1 11  ? 26.716 16.485  28.462 1.00 13.46 ? 11  C   B C2     1 
ATOM   242  O O2     . C   A 1 11  ? 27.278 16.202  27.405 1.00 13.74 ? 11  C   B O2     1 
ATOM   243  N N3     . C   A 1 11  ? 25.399 16.728  28.505 1.00 13.48 ? 11  C   B N3     1 
ATOM   244  C C4     . C   A 1 11  ? 24.837 17.085  29.652 1.00 14.19 ? 11  C   B C4     1 
ATOM   245  N N4     . C   A 1 11  ? 23.534 17.382  29.644 1.00 17.07 ? 11  C   B N4     1 
ATOM   246  C C5     . C   A 1 11  ? 25.585 17.174  30.863 1.00 15.91 ? 11  C   B C5     1 
ATOM   247  C C6     . C   A 1 11  ? 26.888 16.908  30.802 1.00 13.57 ? 11  C   B C6     1 
ATOM   248  H "HO2'" . C   A 1 11  ? 30.488 16.493  27.468 1.00 20.00 ? 11  C   B "HO2'" 1 
ATOM   249  H H41    . C   A 1 11  ? 23.087 17.680  30.499 1.00 20.00 ? 11  C   B H41    1 
ATOM   250  H H42    . C   A 1 11  ? 22.991 17.324  28.787 1.00 20.00 ? 11  C   B H42    1 
ATOM   251  P P      . C   A 1 12  ? 30.617 20.799  29.665 1.00 16.11 ? 12  C   B P      1 
ATOM   252  O OP1    . C   A 1 12  ? 31.860 21.507  30.076 1.00 15.78 ? 12  C   B OP1    1 
ATOM   253  O OP2    . C   A 1 12  ? 29.360 21.091  30.365 1.00 14.29 ? 12  C   B OP2    1 
ATOM   254  O "O5'"  . C   A 1 12  ? 30.389 20.979  28.106 1.00 11.35 ? 12  C   B "O5'"  1 
ATOM   255  C "C5'"  . C   A 1 12  ? 29.142 21.372  27.593 1.00 8.97  ? 12  C   B "C5'"  1 
ATOM   256  C "C4'"  . C   A 1 12  ? 29.031 20.952  26.162 1.00 5.08  ? 12  C   B "C4'"  1 
ATOM   257  O "O4'"  . C   A 1 12  ? 28.395 19.665  26.146 1.00 4.73  ? 12  C   B "O4'"  1 
ATOM   258  C "C3'"  . C   A 1 12  ? 28.158 21.822  25.284 1.00 4.21  ? 12  C   B "C3'"  1 
ATOM   259  O "O3'"  . C   A 1 12  ? 28.932 22.863  24.714 1.00 6.58  ? 12  C   B "O3'"  1 
ATOM   260  C "C2'"  . C   A 1 12  ? 27.702 20.825  24.242 1.00 6.28  ? 12  C   B "C2'"  1 
ATOM   261  O "O2'"  . C   A 1 12  ? 28.735 20.444  23.351 1.00 5.66  ? 12  C   B "O2'"  1 
ATOM   262  C "C1'"  . C   A 1 12  ? 27.405 19.632  25.140 1.00 7.85  ? 12  C   B "C1'"  1 
ATOM   263  N N1     . C   A 1 12  ? 26.116 19.758  25.810 1.00 9.65  ? 12  C   B N1     1 
ATOM   264  C C2     . C   A 1 12  ? 24.959 19.417  25.150 1.00 13.64 ? 12  C   B C2     1 
ATOM   265  O O2     . C   A 1 12  ? 25.032 19.012  23.982 1.00 15.78 ? 12  C   B O2     1 
ATOM   266  N N3     . C   A 1 12  ? 23.769 19.530  25.786 1.00 14.42 ? 12  C   B N3     1 
ATOM   267  C C4     . C   A 1 12  ? 23.743 19.969  27.047 1.00 19.02 ? 12  C   B C4     1 
ATOM   268  N N4     . C   A 1 12  ? 22.572 20.082  27.656 1.00 19.32 ? 12  C   B N4     1 
ATOM   269  C C5     . C   A 1 12  ? 24.914 20.317  27.738 1.00 16.43 ? 12  C   B C5     1 
ATOM   270  C C6     . C   A 1 12  ? 26.072 20.207  27.094 1.00 12.22 ? 12  C   B C6     1 
ATOM   271  H "HO2'" . C   A 1 12  ? 28.343 19.825  22.730 1.00 20.00 ? 12  C   B "HO2'" 1 
ATOM   272  H H41    . C   A 1 12  ? 22.537 20.432  28.599 1.00 20.00 ? 12  C   B H41    1 
ATOM   273  H H42    . C   A 1 12  ? 21.720 19.885  27.155 1.00 20.00 ? 12  C   B H42    1 
ATOM   274  P P      . A   A 1 13  ? 28.367 24.355  24.734 1.00 6.56  ? 13  A   B P      1 
ATOM   275  O OP1    . A   A 1 13  ? 29.207 25.175  23.848 1.00 2.01  ? 13  A   B OP1    1 
ATOM   276  O OP2    . A   A 1 13  ? 28.195 24.734  26.146 1.00 2.01  ? 13  A   B OP2    1 
ATOM   277  O "O5'"  . A   A 1 13  ? 26.925 24.217  24.098 1.00 6.50  ? 13  A   B "O5'"  1 
ATOM   278  C "C5'"  . A   A 1 13  ? 26.764 23.734  22.784 1.00 10.51 ? 13  A   B "C5'"  1 
ATOM   279  C "C4'"  . A   A 1 13  ? 25.293 23.644  22.465 1.00 15.97 ? 13  A   B "C4'"  1 
ATOM   280  O "O4'"  . A   A 1 13  ? 24.668 22.655  23.322 1.00 18.58 ? 13  A   B "O4'"  1 
ATOM   281  C "C3'"  . A   A 1 13  ? 24.472 24.898  22.702 1.00 16.21 ? 13  A   B "C3'"  1 
ATOM   282  O "O3'"  . A   A 1 13  ? 24.641 25.749  21.572 1.00 18.51 ? 13  A   B "O3'"  1 
ATOM   283  C "C2'"  . A   A 1 13  ? 23.062 24.316  22.822 1.00 19.41 ? 13  A   B "C2'"  1 
ATOM   284  O "O2'"  . A   A 1 13  ? 22.556 23.887  21.581 1.00 19.94 ? 13  A   B "O2'"  1 
ATOM   285  C "C1'"  . A   A 1 13  ? 23.328 23.031  23.600 1.00 20.38 ? 13  A   B "C1'"  1 
ATOM   286  N N9     . A   A 1 13  ? 23.159 23.125  25.051 1.00 23.67 ? 13  A   B N9     1 
ATOM   287  C C8     . A   A 1 13  ? 24.120 23.341  26.000 1.00 26.85 ? 13  A   B C8     1 
ATOM   288  N N7     . A   A 1 13  ? 23.656 23.395  27.221 1.00 28.24 ? 13  A   B N7     1 
ATOM   289  C C5     . A   A 1 13  ? 22.294 23.204  27.064 1.00 26.81 ? 13  A   B C5     1 
ATOM   290  C C6     . A   A 1 13  ? 21.230 23.174  27.985 1.00 26.87 ? 13  A   B C6     1 
ATOM   291  N N6     . A   A 1 13  ? 21.377 23.344  29.309 1.00 27.36 ? 13  A   B N6     1 
ATOM   292  N N1     . A   A 1 13  ? 19.989 22.965  27.491 1.00 29.43 ? 13  A   B N1     1 
ATOM   293  C C2     . A   A 1 13  ? 19.842 22.789  26.179 1.00 30.03 ? 13  A   B C2     1 
ATOM   294  N N3     . A   A 1 13  ? 20.758 22.793  25.225 1.00 29.66 ? 13  A   B N3     1 
ATOM   295  C C4     . A   A 1 13  ? 21.979 23.018  25.739 1.00 26.19 ? 13  A   B C4     1 
ATOM   296  H "HO2'" . A   A 1 13  ? 21.668 23.580  21.752 1.00 20.00 ? 13  A   B "HO2'" 1 
ATOM   297  H H61    . A   A 1 13  ? 22.292 23.518  29.697 1.00 20.00 ? 13  A   B H61    1 
ATOM   298  H H62    . A   A 1 13  ? 20.567 23.326  29.913 1.00 20.00 ? 13  A   B H62    1 
ATOM   299  P P      . A   A 1 14  ? 23.862 27.142  21.494 1.00 21.86 ? 14  A   B P      1 
ATOM   300  O OP1    . A   A 1 14  ? 24.459 27.922  20.377 1.00 23.96 ? 14  A   B OP1    1 
ATOM   301  O OP2    . A   A 1 14  ? 23.795 27.762  22.836 1.00 23.86 ? 14  A   B OP2    1 
ATOM   302  O "O5'"  . A   A 1 14  ? 22.397 26.710  21.074 1.00 25.27 ? 14  A   B "O5'"  1 
ATOM   303  C "C5'"  . A   A 1 14  ? 21.341 27.652  21.045 1.00 32.58 ? 14  A   B "C5'"  1 
ATOM   304  C "C4'"  . A   A 1 14  ? 20.048 26.983  20.662 1.00 38.15 ? 14  A   B "C4'"  1 
ATOM   305  O "O4'"  . A   A 1 14  ? 19.874 25.785  21.460 1.00 39.22 ? 14  A   B "O4'"  1 
ATOM   306  C "C3'"  . A   A 1 14  ? 18.796 27.815  20.899 1.00 42.74 ? 14  A   B "C3'"  1 
ATOM   307  O "O3'"  . A   A 1 14  ? 18.502 28.604  19.738 1.00 44.54 ? 14  A   B "O3'"  1 
ATOM   308  C "C2'"  . A   A 1 14  ? 17.735 26.737  21.090 1.00 42.15 ? 14  A   B "C2'"  1 
ATOM   309  O "O2'"  . A   A 1 14  ? 17.325 26.218  19.846 1.00 38.74 ? 14  A   B "O2'"  1 
ATOM   310  C "C1'"  . A   A 1 14  ? 18.517 25.651  21.832 1.00 40.57 ? 14  A   B "C1'"  1 
ATOM   311  N N9     . A   A 1 14  ? 18.440 25.732  23.288 1.00 40.20 ? 14  A   B N9     1 
ATOM   312  C C8     . A   A 1 14  ? 19.473 25.962  24.162 1.00 44.10 ? 14  A   B C8     1 
ATOM   313  N N7     . A   A 1 14  ? 19.109 25.992  25.413 1.00 43.77 ? 14  A   B N7     1 
ATOM   314  C C5     . A   A 1 14  ? 17.749 25.762  25.371 1.00 43.14 ? 14  A   B C5     1 
ATOM   315  C C6     . A   A 1 14  ? 16.776 25.676  26.383 1.00 44.72 ? 14  A   B C6     1 
ATOM   316  N N6     . A   A 1 14  ? 17.042 25.823  27.690 1.00 43.09 ? 14  A   B N6     1 
ATOM   317  N N1     . A   A 1 14  ? 15.504 25.432  26.006 1.00 42.50 ? 14  A   B N1     1 
ATOM   318  C C2     . A   A 1 14  ? 15.241 25.293  24.696 1.00 42.67 ? 14  A   B C2     1 
ATOM   319  N N3     . A   A 1 14  ? 16.071 25.354  23.655 1.00 42.05 ? 14  A   B N3     1 
ATOM   320  C C4     . A   A 1 14  ? 17.320 25.597  24.068 1.00 40.27 ? 14  A   B C4     1 
ATOM   321  H "HO2'" . A   A 1 14  ? 16.672 25.544  20.021 1.00 20.00 ? 14  A   B "HO2'" 1 
ATOM   322  H H61    . A   A 1 14  ? 17.983 26.008  28.007 1.00 20.00 ? 14  A   B H61    1 
ATOM   323  H H62    . A   A 1 14  ? 16.298 25.754  28.370 1.00 20.00 ? 14  A   B H62    1 
ATOM   324  P P      . G   A 1 15  ? 18.791 30.189  19.732 1.00 49.28 ? 15  G   B P      1 
ATOM   325  O OP1    . G   A 1 15  ? 18.659 30.669  18.332 1.00 48.73 ? 15  G   B OP1    1 
ATOM   326  O OP2    . G   A 1 15  ? 20.041 30.470  20.488 1.00 50.90 ? 15  G   B OP2    1 
ATOM   327  O "O5'"  . G   A 1 15  ? 17.592 30.807  20.562 1.00 51.91 ? 15  G   B "O5'"  1 
ATOM   328  C "C5'"  . G   A 1 15  ? 16.286 30.293  20.411 1.00 53.92 ? 15  G   B "C5'"  1 
ATOM   329  C "C4'"  . G   A 1 15  ? 15.539 30.425  21.700 1.00 54.43 ? 15  G   B "C4'"  1 
ATOM   330  O "O4'"  . G   A 1 15  ? 16.207 29.631  22.701 1.00 53.58 ? 15  G   B "O4'"  1 
ATOM   331  C "C3'"  . G   A 1 15  ? 15.529 31.828  22.287 1.00 57.02 ? 15  G   B "C3'"  1 
ATOM   332  O "O3'"  . G   A 1 15  ? 14.554 32.599  21.562 1.00 58.28 ? 15  G   B "O3'"  1 
ATOM   333  C "C2'"  . G   A 1 15  ? 15.326 31.582  23.786 1.00 52.28 ? 15  G   B "C2'"  1 
ATOM   334  O "O2'"  . G   A 1 15  ? 13.985 31.524  24.203 1.00 54.16 ? 15  G   B "O2'"  1 
ATOM   335  C "C1'"  . G   A 1 15  ? 15.923 30.177  23.968 1.00 49.04 ? 15  G   B "C1'"  1 
ATOM   336  N N9     . G   A 1 15  ? 17.068 30.004  24.856 1.00 41.98 ? 15  G   B N9     1 
ATOM   337  C C8     . G   A 1 15  ? 18.403 30.204  24.582 1.00 39.88 ? 15  G   B C8     1 
ATOM   338  N N7     . G   A 1 15  ? 19.178 29.889  25.585 1.00 38.63 ? 15  G   B N7     1 
ATOM   339  C C5     . G   A 1 15  ? 18.306 29.473  26.578 1.00 39.23 ? 15  G   B C5     1 
ATOM   340  C C6     . G   A 1 15  ? 18.549 29.000  27.900 1.00 39.10 ? 15  G   B C6     1 
ATOM   341  O O6     . G   A 1 15  ? 19.629 28.846  28.478 1.00 36.44 ? 15  G   B O6     1 
ATOM   342  N N1     . G   A 1 15  ? 17.377 28.692  28.562 1.00 36.91 ? 15  G   B N1     1 
ATOM   343  C C2     . G   A 1 15  ? 16.122 28.811  28.037 1.00 37.53 ? 15  G   B C2     1 
ATOM   344  N N2     . G   A 1 15  ? 15.117 28.449  28.837 1.00 36.74 ? 15  G   B N2     1 
ATOM   345  N N3     . G   A 1 15  ? 15.871 29.251  26.814 1.00 36.68 ? 15  G   B N3     1 
ATOM   346  C C4     . G   A 1 15  ? 16.996 29.556  26.147 1.00 38.87 ? 15  G   B C4     1 
ATOM   347  H "HO2'" . G   A 1 15  ? 14.009 31.373  25.147 1.00 20.00 ? 15  G   B "HO2'" 1 
ATOM   348  H H1     . G   A 1 15  ? 17.455 28.363  29.515 1.00 20.00 ? 15  G   B H1     1 
ATOM   349  H H21    . G   A 1 15  ? 14.168 28.529  28.505 1.00 20.00 ? 15  G   B H21    1 
ATOM   350  H H22    . G   A 1 15  ? 15.297 28.136  29.781 1.00 20.00 ? 15  G   B H22    1 
ATOM   351  P P      . C   A 1 16  ? 13.398 33.438  22.324 1.00 59.53 ? 16  C   B P      1 
ATOM   352  O OP1    . C   A 1 16  ? 12.377 32.495  22.862 1.00 60.37 ? 16  C   B OP1    1 
ATOM   353  O OP2    . C   A 1 16  ? 12.974 34.473  21.343 1.00 59.21 ? 16  C   B OP2    1 
ATOM   354  O "O5'"  . C   A 1 16  ? 14.131 34.202  23.518 1.00 60.62 ? 16  C   B "O5'"  1 
ATOM   355  C "C5'"  . C   A 1 16  ? 13.585 35.408  24.061 1.00 61.57 ? 16  C   B "C5'"  1 
ATOM   356  C "C4'"  . C   A 1 16  ? 14.254 36.599  23.422 1.00 62.11 ? 16  C   B "C4'"  1 
ATOM   357  O "O4'"  . C   A 1 16  ? 15.670 36.328  23.385 1.00 61.42 ? 16  C   B "O4'"  1 
ATOM   358  C "C3'"  . C   A 1 16  ? 13.854 36.800  21.960 1.00 62.89 ? 16  C   B "C3'"  1 
ATOM   359  O "O3'"  . C   A 1 16  ? 12.733 37.679  21.763 1.00 63.04 ? 16  C   B "O3'"  1 
ATOM   360  C "C2'"  . C   A 1 16  ? 15.102 37.407  21.320 1.00 60.78 ? 16  C   B "C2'"  1 
ATOM   361  O "O2'"  . C   A 1 16  ? 15.142 38.820  21.322 1.00 61.50 ? 16  C   B "O2'"  1 
ATOM   362  C "C1'"  . C   A 1 16  ? 16.223 36.859  22.202 1.00 61.21 ? 16  C   B "C1'"  1 
ATOM   363  N N1     . C   A 1 16  ? 17.080 35.854  21.560 1.00 56.49 ? 16  C   B N1     1 
ATOM   364  C C2     . C   A 1 16  ? 17.922 36.280  20.530 1.00 56.64 ? 16  C   B C2     1 
ATOM   365  O O2     . C   A 1 16  ? 17.864 37.470  20.168 1.00 55.35 ? 16  C   B O2     1 
ATOM   366  N N3     . C   A 1 16  ? 18.769 35.396  19.953 1.00 56.63 ? 16  C   B N3     1 
ATOM   367  C C4     . C   A 1 16  ? 18.784 34.128  20.359 1.00 55.73 ? 16  C   B C4     1 
ATOM   368  N N4     . C   A 1 16  ? 19.653 33.303  19.770 1.00 58.14 ? 16  C   B N4     1 
ATOM   369  C C5     . C   A 1 16  ? 17.914 33.656  21.396 1.00 59.40 ? 16  C   B C5     1 
ATOM   370  C C6     . C   A 1 16  ? 17.080 34.546  21.962 1.00 55.78 ? 16  C   B C6     1 
ATOM   371  H "HO2'" . C   A 1 16  ? 15.956 39.081  20.893 1.00 20.00 ? 16  C   B "HO2'" 1 
ATOM   372  H H41    . C   A 1 16  ? 19.724 32.344  20.081 1.00 20.00 ? 16  C   B H41    1 
ATOM   373  H H42    . C   A 1 16  ? 20.276 33.656  19.058 1.00 20.00 ? 16  C   B H42    1 
ATOM   374  P P      . G   A 1 17  ? 12.282 38.734  22.908 1.00 61.28 ? 18  G   B P      1 
ATOM   375  O OP1    . G   A 1 17  ? 10.921 39.198  22.536 1.00 63.38 ? 18  G   B OP1    1 
ATOM   376  O OP2    . G   A 1 17  ? 13.362 39.736  23.106 1.00 61.46 ? 18  G   B OP2    1 
ATOM   377  O "O5'"  . G   A 1 17  ? 12.138 37.892  24.254 1.00 58.28 ? 18  G   B "O5'"  1 
ATOM   378  C "C5'"  . G   A 1 17  ? 12.020 38.566  25.498 1.00 55.63 ? 18  G   B "C5'"  1 
ATOM   379  C "C4'"  . G   A 1 17  ? 10.790 38.103  26.237 1.00 51.42 ? 18  G   B "C4'"  1 
ATOM   380  O "O4'"  . G   A 1 17  ? 10.498 39.026  27.287 1.00 51.06 ? 18  G   B "O4'"  1 
ATOM   381  C "C3'"  . G   A 1 17  ? 9.515  37.997  25.410 1.00 53.08 ? 18  G   B "C3'"  1 
ATOM   382  O "O3'"  . G   A 1 17  ? 9.423  36.588  25.196 1.00 54.91 ? 18  G   B "O3'"  1 
ATOM   383  C "C2'"  . G   A 1 17  ? 8.381  38.466  26.328 1.00 51.62 ? 18  G   B "C2'"  1 
ATOM   384  O "O2'"  . G   A 1 17  ? 7.562  37.387  26.671 1.00 52.15 ? 18  G   B "O2'"  1 
ATOM   385  C "C1'"  . G   A 1 17  ? 9.132  38.952  27.574 1.00 51.21 ? 18  G   B "C1'"  1 
ATOM   386  N N9     . G   A 1 17  ? 8.745  40.131  28.340 1.00 50.21 ? 18  G   B N9     1 
ATOM   387  C C8     . G   A 1 17  ? 8.712  41.443  27.934 1.00 47.59 ? 18  G   B C8     1 
ATOM   388  N N7     . G   A 1 17  ? 8.434  42.271  28.908 1.00 49.56 ? 18  G   B N7     1 
ATOM   389  C C5     . G   A 1 17  ? 8.249  41.453  30.016 1.00 48.78 ? 18  G   B C5     1 
ATOM   390  C C6     . G   A 1 17  ? 7.943  41.784  31.369 1.00 50.24 ? 18  G   B C6     1 
ATOM   391  O O6     . G   A 1 17  ? 7.783  42.906  31.874 1.00 49.94 ? 18  G   B O6     1 
ATOM   392  N N1     . G   A 1 17  ? 7.837  40.644  32.167 1.00 51.22 ? 18  G   B N1     1 
ATOM   393  C C2     . G   A 1 17  ? 8.019  39.352  31.720 1.00 51.88 ? 18  G   B C2     1 
ATOM   394  N N2     . G   A 1 17  ? 7.884  38.366  32.642 1.00 52.84 ? 18  G   B N2     1 
ATOM   395  N N3     . G   A 1 17  ? 8.313  39.037  30.463 1.00 50.73 ? 18  G   B N3     1 
ATOM   396  C C4     . G   A 1 17  ? 8.411  40.129  29.675 1.00 48.96 ? 18  G   B C4     1 
ATOM   397  H "HO2'" . G   A 1 17  ? 6.912  37.742  27.266 1.00 20.00 ? 18  G   B "HO2'" 1 
ATOM   398  H H1     . G   A 1 17  ? 7.587  40.766  33.138 1.00 20.00 ? 18  G   B H1     1 
ATOM   399  H H21    . G   A 1 17  ? 8.001  37.402  32.373 1.00 20.00 ? 18  G   B H21    1 
ATOM   400  H H22    . G   A 1 17  ? 7.638  38.584  33.604 1.00 20.00 ? 18  G   B H22    1 
ATOM   401  P P      . G   A 1 18  ? 8.323  35.982  24.211 1.00 58.16 ? 19  G   B P      1 
ATOM   402  O OP1    . G   A 1 18  ? 8.985  34.949  23.364 1.00 57.49 ? 19  G   B OP1    1 
ATOM   403  O OP2    . G   A 1 18  ? 7.709  37.180  23.581 1.00 58.06 ? 19  G   B OP2    1 
ATOM   404  O "O5'"  . G   A 1 18  ? 7.240  35.279  25.154 1.00 59.82 ? 19  G   B "O5'"  1 
ATOM   405  C "C5'"  . G   A 1 18  ? 7.579  34.232  26.074 1.00 58.52 ? 19  G   B "C5'"  1 
ATOM   406  C "C4'"  . G   A 1 18  ? 6.309  33.675  26.695 1.00 59.14 ? 19  G   B "C4'"  1 
ATOM   407  O "O4'"  . G   A 1 18  ? 5.528  34.774  27.184 1.00 57.44 ? 19  G   B "O4'"  1 
ATOM   408  C "C3'"  . G   A 1 18  ? 5.438  32.853  25.756 1.00 58.20 ? 19  G   B "C3'"  1 
ATOM   409  O "O3'"  . G   A 1 18  ? 5.609  31.524  26.267 1.00 56.94 ? 19  G   B "O3'"  1 
ATOM   410  C "C2'"  . G   A 1 18  ? 4.000  33.361  25.957 1.00 55.24 ? 19  G   B "C2'"  1 
ATOM   411  O "O2'"  . G   A 1 18  ? 3.176  32.476  26.669 1.00 54.98 ? 19  G   B "O2'"  1 
ATOM   412  C "C1'"  . G   A 1 18  ? 4.188  34.610  26.819 1.00 53.56 ? 19  G   B "C1'"  1 
ATOM   413  N N9     . G   A 1 18  ? 3.670  35.923  26.461 1.00 47.93 ? 19  G   B N9     1 
ATOM   414  C C8     . G   A 1 18  ? 3.891  36.688  25.337 1.00 46.12 ? 19  G   B C8     1 
ATOM   415  N N7     . G   A 1 18  ? 3.395  37.896  25.433 1.00 44.73 ? 19  G   B N7     1 
ATOM   416  C C5     . G   A 1 18  ? 2.782  37.912  26.684 1.00 45.36 ? 19  G   B C5     1 
ATOM   417  C C6     . G   A 1 18  ? 2.103  38.953  27.377 1.00 44.03 ? 19  G   B C6     1 
ATOM   418  O O6     . G   A 1 18  ? 1.910  40.125  27.021 1.00 41.92 ? 19  G   B O6     1 
ATOM   419  N N1     . G   A 1 18  ? 1.641  38.521  28.620 1.00 40.17 ? 19  G   B N1     1 
ATOM   420  C C2     . G   A 1 18  ? 1.816  37.257  29.129 1.00 42.85 ? 19  G   B C2     1 
ATOM   421  N N2     . G   A 1 18  ? 1.299  37.003  30.340 1.00 41.63 ? 19  G   B N2     1 
ATOM   422  N N3     . G   A 1 18  ? 2.454  36.298  28.505 1.00 42.91 ? 19  G   B N3     1 
ATOM   423  C C4     . G   A 1 18  ? 2.909  36.690  27.299 1.00 45.43 ? 19  G   B C4     1 
ATOM   424  H "HO2'" . G   A 1 18  ? 2.312  32.890  26.705 1.00 20.00 ? 19  G   B "HO2'" 1 
ATOM   425  H H1     . G   A 1 18  ? 1.133  39.175  29.195 1.00 20.00 ? 19  G   B H1     1 
ATOM   426  H H21    . G   A 1 18  ? 1.384  36.080  30.741 1.00 20.00 ? 19  G   B H21    1 
ATOM   427  H H22    . G   A 1 18  ? 0.788  37.709  30.851 1.00 20.00 ? 19  G   B H22    1 
ATOM   428  P P      . U   A 1 19  ? 5.044  30.240  25.482 1.00 59.40 ? 20  U   B P      1 
ATOM   429  O OP1    . U   A 1 19  ? 6.004  29.918  24.393 1.00 59.21 ? 20  U   B OP1    1 
ATOM   430  O OP2    . U   A 1 19  ? 3.601  30.431  25.156 1.00 57.11 ? 20  U   B OP2    1 
ATOM   431  O "O5'"  . U   A 1 19  ? 5.186  29.079  26.563 1.00 59.68 ? 20  U   B "O5'"  1 
ATOM   432  C "C5'"  . U   A 1 19  ? 6.468  28.739  27.095 1.00 60.11 ? 20  U   B "C5'"  1 
ATOM   433  C "C4'"  . U   A 1 19  ? 6.449  28.838  28.600 1.00 59.51 ? 20  U   B "C4'"  1 
ATOM   434  O "O4'"  . U   A 1 19  ? 6.076  30.185  28.968 1.00 59.00 ? 20  U   B "O4'"  1 
ATOM   435  C "C3'"  . U   A 1 19  ? 5.427  27.941  29.277 1.00 59.58 ? 20  U   B "C3'"  1 
ATOM   436  O "O3'"  . U   A 1 19  ? 5.933  26.601  29.422 1.00 58.58 ? 20  U   B "O3'"  1 
ATOM   437  C "C2'"  . U   A 1 19  ? 4.983  28.716  30.531 1.00 56.48 ? 20  U   B "C2'"  1 
ATOM   438  O "O2'"  . U   A 1 19  ? 5.533  28.366  31.788 1.00 55.03 ? 20  U   B "O2'"  1 
ATOM   439  C "C1'"  . U   A 1 19  ? 5.343  30.163  30.177 1.00 57.78 ? 20  U   B "C1'"  1 
ATOM   440  N N1     . U   A 1 19  ? 4.223  31.112  30.076 1.00 55.68 ? 20  U   B N1     1 
ATOM   441  C C2     . U   A 1 19  ? 4.145  32.086  31.058 1.00 55.49 ? 20  U   B C2     1 
ATOM   442  O O2     . U   A 1 19  ? 4.919  32.128  32.008 1.00 53.45 ? 20  U   B O2     1 
ATOM   443  N N3     . U   A 1 19  ? 3.124  32.995  30.897 1.00 55.85 ? 20  U   B N3     1 
ATOM   444  C C4     . U   A 1 19  ? 2.173  33.011  29.893 1.00 57.04 ? 20  U   B C4     1 
ATOM   445  O O4     . U   A 1 19  ? 1.327  33.907  29.871 1.00 57.04 ? 20  U   B O4     1 
ATOM   446  C C5     . U   A 1 19  ? 2.298  31.944  28.940 1.00 58.52 ? 20  U   B C5     1 
ATOM   447  C C6     . U   A 1 19  ? 3.299  31.058  29.058 1.00 57.12 ? 20  U   B C6     1 
ATOM   448  H "HO2'" . U   A 1 19  ? 5.116  28.934  32.435 1.00 20.00 ? 20  U   B "HO2'" 1 
ATOM   449  H H3     . U   A 1 19  ? 3.070  33.733  31.590 1.00 20.00 ? 20  U   B H3     1 
ATOM   450  P P      . A   A 1 20  ? 7.155  26.271  30.439 1.00 59.39 ? 21  A   B P      1 
ATOM   451  O OP1    . A   A 1 20  ? 6.817  24.992  31.131 1.00 59.27 ? 21  A   B OP1    1 
ATOM   452  O OP2    . A   A 1 20  ? 7.565  27.456  31.247 1.00 59.61 ? 21  A   B OP2    1 
ATOM   453  O "O5'"  . A   A 1 20  ? 8.392  25.985  29.477 1.00 60.34 ? 21  A   B "O5'"  1 
ATOM   454  C "C5'"  . A   A 1 20  ? 9.123  24.766  29.566 1.00 58.62 ? 21  A   B "C5'"  1 
ATOM   455  C "C4'"  . A   A 1 20  ? 10.457 24.902  28.868 1.00 55.74 ? 21  A   B "C4'"  1 
ATOM   456  O "O4'"  . A   A 1 20  ? 11.405 25.623  29.698 1.00 54.81 ? 21  A   B "O4'"  1 
ATOM   457  C "C3'"  . A   A 1 20  ? 11.115 23.569  28.586 1.00 55.29 ? 21  A   B "C3'"  1 
ATOM   458  O "O3'"  . A   A 1 20  ? 10.619 23.149  27.316 1.00 53.12 ? 21  A   B "O3'"  1 
ATOM   459  C "C2'"  . A   A 1 20  ? 12.606 23.899  28.550 1.00 54.61 ? 21  A   B "C2'"  1 
ATOM   460  O "O2'"  . A   A 1 20  ? 13.032 24.316  27.276 1.00 54.38 ? 21  A   B "O2'"  1 
ATOM   461  C "C1'"  . A   A 1 20  ? 12.702 25.083  29.519 1.00 52.58 ? 21  A   B "C1'"  1 
ATOM   462  N N9     . A   A 1 20  ? 13.280 24.802  30.835 1.00 48.28 ? 21  A   B N9     1 
ATOM   463  C C8     . A   A 1 20  ? 12.623 24.502  32.011 1.00 46.55 ? 21  A   B C8     1 
ATOM   464  N N7     . A   A 1 20  ? 13.420 24.376  33.048 1.00 44.39 ? 21  A   B N7     1 
ATOM   465  C C5     . A   A 1 20  ? 14.685 24.592  32.519 1.00 44.39 ? 21  A   B C5     1 
ATOM   466  C C6     . A   A 1 20  ? 15.959 24.612  33.108 1.00 46.12 ? 21  A   B C6     1 
ATOM   467  N N6     . A   A 1 20  ? 16.180 24.429  34.406 1.00 47.43 ? 21  A   B N6     1 
ATOM   468  N N1     . A   A 1 20  ? 17.015 24.840  32.299 1.00 45.86 ? 21  A   B N1     1 
ATOM   469  C C2     . A   A 1 20  ? 16.798 25.049  30.993 1.00 44.53 ? 21  A   B C2     1 
ATOM   470  N N3     . A   A 1 20  ? 15.646 25.069  30.324 1.00 44.45 ? 21  A   B N3     1 
ATOM   471  C C4     . A   A 1 20  ? 14.615 24.831  31.157 1.00 45.86 ? 21  A   B C4     1 
ATOM   472  H "HO2'" . A   A 1 20  ? 13.971 24.494  27.333 1.00 20.00 ? 21  A   B "HO2'" 1 
ATOM   473  H H61    . A   A 1 20  ? 15.408 24.262  35.035 1.00 20.00 ? 21  A   B H61    1 
ATOM   474  H H62    . A   A 1 20  ? 17.121 24.459  34.769 1.00 20.00 ? 21  A   B H62    1 
ATOM   475  P P      . A   A 1 21  ? 10.878 21.654  26.802 1.00 50.85 ? 22  A   B P      1 
ATOM   476  O OP1    . A   A 1 21  ? 9.603  21.105  26.258 1.00 50.42 ? 22  A   B OP1    1 
ATOM   477  O OP2    . A   A 1 21  ? 11.595 20.911  27.879 1.00 49.50 ? 22  A   B OP2    1 
ATOM   478  O "O5'"  . A   A 1 21  ? 11.894 21.870  25.598 1.00 49.33 ? 22  A   B "O5'"  1 
ATOM   479  C "C5'"  . A   A 1 21  ? 12.572 20.774  25.002 1.00 46.40 ? 22  A   B "C5'"  1 
ATOM   480  C "C4'"  . A   A 1 21  ? 12.695 21.017  23.526 1.00 38.46 ? 22  A   B "C4'"  1 
ATOM   481  O "O4'"  . A   A 1 21  ? 13.407 22.262  23.307 1.00 40.29 ? 22  A   B "O4'"  1 
ATOM   482  C "C3'"  . A   A 1 21  ? 13.499 19.997  22.756 1.00 37.44 ? 22  A   B "C3'"  1 
ATOM   483  O "O3'"  . A   A 1 21  ? 12.674 18.895  22.437 1.00 34.32 ? 22  A   B "O3'"  1 
ATOM   484  C "C2'"  . A   A 1 21  ? 13.884 20.801  21.525 1.00 37.62 ? 22  A   B "C2'"  1 
ATOM   485  O "O2'"  . A   A 1 21  ? 12.773 20.987  20.670 1.00 35.07 ? 22  A   B "O2'"  1 
ATOM   486  C "C1'"  . A   A 1 21  ? 14.233 22.147  22.151 1.00 38.81 ? 22  A   B "C1'"  1 
ATOM   487  N N9     . A   A 1 21  ? 15.645 22.257  22.558 1.00 39.38 ? 22  A   B N9     1 
ATOM   488  C C8     . A   A 1 21  ? 16.171 22.350  23.824 1.00 37.36 ? 22  A   B C8     1 
ATOM   489  N N7     . A   A 1 21  ? 17.485 22.391  23.853 1.00 38.00 ? 22  A   B N7     1 
ATOM   490  C C5     . A   A 1 21  ? 17.848 22.325  22.517 1.00 36.29 ? 22  A   B C5     1 
ATOM   491  C C6     . A   A 1 21  ? 19.102 22.326  21.873 1.00 37.22 ? 22  A   B C6     1 
ATOM   492  N N6     . A   A 1 21  ? 20.273 22.369  22.516 1.00 36.97 ? 22  A   B N6     1 
ATOM   493  N N1     . A   A 1 21  ? 19.114 22.268  20.525 1.00 37.32 ? 22  A   B N1     1 
ATOM   494  C C2     . A   A 1 21  ? 17.944 22.218  19.879 1.00 37.54 ? 22  A   B C2     1 
ATOM   495  N N3     . A   A 1 21  ? 16.703 22.204  20.370 1.00 36.23 ? 22  A   B N3     1 
ATOM   496  C C4     . A   A 1 21  ? 16.726 22.261  21.707 1.00 37.80 ? 22  A   B C4     1 
ATOM   497  H "HO2'" . A   A 1 21  ? 13.106 21.480  19.922 1.00 20.00 ? 22  A   B "HO2'" 1 
ATOM   498  H H61    . A   A 1 21  ? 20.289 22.420  23.525 1.00 20.00 ? 22  A   B H61    1 
ATOM   499  H H62    . A   A 1 21  ? 21.138 22.357  21.999 1.00 20.00 ? 22  A   B H62    1 
ATOM   500  P P      . G   A 1 22  ? 13.114 17.420  22.899 1.00 31.50 ? 23  G   B P      1 
ATOM   501  O OP1    . G   A 1 22  ? 12.089 16.475  22.389 1.00 32.57 ? 23  G   B OP1    1 
ATOM   502  O OP2    . G   A 1 22  ? 13.419 17.460  24.363 1.00 32.70 ? 23  G   B OP2    1 
ATOM   503  O "O5'"  . G   A 1 22  ? 14.461 17.155  22.099 1.00 32.76 ? 23  G   B "O5'"  1 
ATOM   504  C "C5'"  . G   A 1 22  ? 14.469 17.201  20.685 1.00 32.24 ? 23  G   B "C5'"  1 
ATOM   505  C "C4'"  . G   A 1 22  ? 15.859 17.443  20.180 1.00 32.25 ? 23  G   B "C4'"  1 
ATOM   506  O "O4'"  . G   A 1 22  ? 16.351 18.730  20.656 1.00 33.66 ? 23  G   B "O4'"  1 
ATOM   507  C "C3'"  . G   A 1 22  ? 16.906 16.481  20.680 1.00 29.57 ? 23  G   B "C3'"  1 
ATOM   508  O "O3'"  . G   A 1 22  ? 16.823 15.241  20.017 1.00 27.74 ? 23  G   B "O3'"  1 
ATOM   509  C "C2'"  . G   A 1 22  ? 18.174 17.255  20.356 1.00 30.88 ? 23  G   B "C2'"  1 
ATOM   510  O "O2'"  . G   A 1 22  ? 18.474 17.270  18.971 1.00 30.09 ? 23  G   B "O2'"  1 
ATOM   511  C "C1'"  . G   A 1 22  ? 17.770 18.663  20.800 1.00 33.08 ? 23  G   B "C1'"  1 
ATOM   512  N N9     . G   A 1 22  ? 18.120 18.906  22.204 1.00 33.70 ? 23  G   B N9     1 
ATOM   513  C C8     . G   A 1 22  ? 17.260 19.029  23.265 1.00 33.78 ? 23  G   B C8     1 
ATOM   514  N N7     . G   A 1 22  ? 17.876 19.190  24.404 1.00 35.39 ? 23  G   B N7     1 
ATOM   515  C C5     . G   A 1 22  ? 19.224 19.181  24.077 1.00 36.82 ? 23  G   B C5     1 
ATOM   516  C C6     . G   A 1 22  ? 20.368 19.313  24.900 1.00 38.12 ? 23  G   B C6     1 
ATOM   517  O O6     . G   A 1 22  ? 20.419 19.463  26.117 1.00 39.35 ? 23  G   B O6     1 
ATOM   518  N N1     . G   A 1 22  ? 21.540 19.255  24.163 1.00 39.48 ? 23  G   B N1     1 
ATOM   519  C C2     . G   A 1 22  ? 21.601 19.099  22.805 1.00 38.13 ? 23  G   B C2     1 
ATOM   520  N N2     . G   A 1 22  ? 22.831 19.091  22.281 1.00 40.85 ? 23  G   B N2     1 
ATOM   521  N N3     . G   A 1 22  ? 20.543 18.962  22.023 1.00 36.27 ? 23  G   B N3     1 
ATOM   522  C C4     . G   A 1 22  ? 19.394 19.019  22.722 1.00 34.55 ? 23  G   B C4     1 
ATOM   523  H "HO2'" . G   A 1 22  ? 19.285 17.773  18.877 1.00 20.00 ? 23  G   B "HO2'" 1 
ATOM   524  H H1     . G   A 1 22  ? 22.413 19.380  24.665 1.00 20.00 ? 23  G   B H1     1 
ATOM   525  H H21    . G   A 1 22  ? 22.954 19.011  21.280 1.00 20.00 ? 23  G   B H21    1 
ATOM   526  H H22    . G   A 1 22  ? 23.641 19.226  22.871 1.00 20.00 ? 23  G   B H22    1 
ATOM   527  P P      . G   A 1 23  ? 17.138 13.887  20.827 1.00 28.48 ? 24  G   B P      1 
ATOM   528  O OP1    . G   A 1 23  ? 16.543 12.718  20.123 1.00 28.02 ? 24  G   B OP1    1 
ATOM   529  O OP2    . G   A 1 23  ? 16.819 14.113  22.260 1.00 29.07 ? 24  G   B OP2    1 
ATOM   530  O "O5'"  . G   A 1 23  ? 18.723 13.738  20.733 1.00 29.02 ? 24  G   B "O5'"  1 
ATOM   531  C "C5'"  . G   A 1 23  ? 19.411 13.957  19.501 1.00 28.03 ? 24  G   B "C5'"  1 
ATOM   532  C "C4'"  . G   A 1 23  ? 20.858 14.295  19.766 1.00 26.63 ? 24  G   B "C4'"  1 
ATOM   533  O "O4'"  . G   A 1 23  ? 20.948 15.524  20.534 1.00 23.83 ? 24  G   B "O4'"  1 
ATOM   534  C "C3'"  . G   A 1 23  ? 21.559 13.316  20.677 1.00 25.09 ? 24  G   B "C3'"  1 
ATOM   535  O "O3'"  . G   A 1 23  ? 21.951 12.161  19.982 1.00 27.30 ? 24  G   B "O3'"  1 
ATOM   536  C "C2'"  . G   A 1 23  ? 22.750 14.126  21.159 1.00 25.40 ? 24  G   B "C2'"  1 
ATOM   537  O "O2'"  . G   A 1 23  ? 23.770 14.248  20.192 1.00 27.80 ? 24  G   B "O2'"  1 
ATOM   538  C "C1'"  . G   A 1 23  ? 22.110 15.488  21.347 1.00 23.22 ? 24  G   B "C1'"  1 
ATOM   539  N N9     . G   A 1 23  ? 21.742 15.741  22.732 1.00 25.05 ? 24  G   B N9     1 
ATOM   540  C C8     . G   A 1 23  ? 20.490 15.905  23.258 1.00 24.59 ? 24  G   B C8     1 
ATOM   541  N N7     . G   A 1 23  ? 20.506 16.161  24.545 1.00 25.81 ? 24  G   B N7     1 
ATOM   542  C C5     . G   A 1 23  ? 21.849 16.147  24.876 1.00 25.07 ? 24  G   B C5     1 
ATOM   543  C C6     . G   A 1 23  ? 22.499 16.380  26.117 1.00 24.96 ? 24  G   B C6     1 
ATOM   544  O O6     . G   A 1 23  ? 22.012 16.657  27.207 1.00 26.88 ? 24  G   B O6     1 
ATOM   545  N N1     . G   A 1 23  ? 23.864 16.283  25.992 1.00 24.12 ? 24  G   B N1     1 
ATOM   546  C C2     . G   A 1 23  ? 24.533 16.013  24.840 1.00 24.64 ? 24  G   B C2     1 
ATOM   547  N N2     . G   A 1 23  ? 25.857 15.992  24.935 1.00 25.98 ? 24  G   B N2     1 
ATOM   548  N N3     . G   A 1 23  ? 23.949 15.790  23.682 1.00 25.28 ? 24  G   B N3     1 
ATOM   549  C C4     . G   A 1 23  ? 22.620 15.879  23.769 1.00 24.15 ? 24  G   B C4     1 
ATOM   550  H "HO2'" . G   A 1 23  ? 24.481 14.752  20.588 1.00 20.00 ? 24  G   B "HO2'" 1 
ATOM   551  H H1     . G   A 1 23  ? 24.406 16.432  26.832 1.00 20.00 ? 24  G   B H1     1 
ATOM   552  H H21    . G   A 1 23  ? 26.417 15.805  24.117 1.00 20.00 ? 24  G   B H21    1 
ATOM   553  H H22    . G   A 1 23  ? 26.323 16.156  25.823 1.00 20.00 ? 24  G   B H22    1 
ATOM   554  P P      . C   A 1 24  ? 22.076 10.789  20.796 1.00 28.08 ? 25  C   B P      1 
ATOM   555  O OP1    . C   A 1 24  ? 22.284 9.690   19.824 1.00 28.85 ? 25  C   B OP1    1 
ATOM   556  O OP2    . C   A 1 24  ? 20.904 10.746  21.696 1.00 30.32 ? 25  C   B OP2    1 
ATOM   557  O "O5'"  . C   A 1 24  ? 23.360 10.995  21.722 1.00 27.46 ? 25  C   B "O5'"  1 
ATOM   558  C "C5'"  . C   A 1 24  ? 24.686 10.812  21.220 1.00 25.76 ? 25  C   B "C5'"  1 
ATOM   559  C "C4'"  . C   A 1 24  ? 25.710 11.043  22.313 1.00 21.50 ? 25  C   B "C4'"  1 
ATOM   560  O "O4'"  . C   A 1 24  ? 25.529 12.357  22.884 1.00 20.31 ? 25  C   B "O4'"  1 
ATOM   561  C "C3'"  . C   A 1 24  ? 25.656 10.134  23.534 1.00 24.36 ? 25  C   B "C3'"  1 
ATOM   562  O "O3'"  . C   A 1 24  ? 26.295 8.891   23.281 1.00 29.62 ? 25  C   B "O3'"  1 
ATOM   563  C "C2'"  . C   A 1 24  ? 26.436 10.949  24.557 1.00 22.25 ? 25  C   B "C2'"  1 
ATOM   564  O "O2'"  . C   A 1 24  ? 27.844 10.953  24.381 1.00 24.05 ? 25  C   B "O2'"  1 
ATOM   565  C "C1'"  . C   A 1 24  ? 25.921 12.342  24.243 1.00 20.92 ? 25  C   B "C1'"  1 
ATOM   566  N N1     . C   A 1 24  ? 24.753 12.620  25.047 1.00 19.80 ? 25  C   B N1     1 
ATOM   567  C C2     . C   A 1 24  ? 24.921 12.877  26.390 1.00 19.59 ? 25  C   B C2     1 
ATOM   568  O O2     . C   A 1 24  ? 26.073 12.810  26.869 1.00 23.15 ? 25  C   B O2     1 
ATOM   569  N N3     . C   A 1 24  ? 23.849 13.192  27.150 1.00 21.07 ? 25  C   B N3     1 
ATOM   570  C C4     . C   A 1 24  ? 22.638 13.234  26.585 1.00 21.61 ? 25  C   B C4     1 
ATOM   571  N N4     . C   A 1 24  ? 21.597 13.558  27.351 1.00 21.96 ? 25  C   B N4     1 
ATOM   572  C C5     . C   A 1 24  ? 22.432 12.942  25.215 1.00 21.25 ? 25  C   B C5     1 
ATOM   573  C C6     . C   A 1 24  ? 23.509 12.641  24.482 1.00 21.41 ? 25  C   B C6     1 
ATOM   574  H "HO2'" . C   A 1 24  ? 28.217 11.502  25.070 1.00 20.00 ? 25  C   B "HO2'" 1 
ATOM   575  H H41    . C   A 1 24  ? 20.675 13.588  26.952 1.00 20.00 ? 25  C   B H41    1 
ATOM   576  H H42    . C   A 1 24  ? 21.722 13.761  28.327 1.00 20.00 ? 25  C   B H42    1 
ATOM   577  P P      . A   A 1 25  ? 25.779 7.569   24.026 1.00 31.23 ? 26  A   B P      1 
ATOM   578  O OP1    . A   A 1 25  ? 26.757 6.506   23.656 1.00 30.49 ? 26  A   B OP1    1 
ATOM   579  O OP2    . A   A 1 25  ? 24.348 7.408   23.666 1.00 29.71 ? 26  A   B OP2    1 
ATOM   580  O "O5'"  . A   A 1 25  ? 25.915 7.891   25.580 1.00 29.77 ? 26  A   B "O5'"  1 
ATOM   581  C "C5'"  . A   A 1 25  ? 27.182 7.825   26.220 1.00 32.82 ? 26  A   B "C5'"  1 
ATOM   582  C "C4'"  . A   A 1 25  ? 27.056 8.192   27.676 1.00 34.14 ? 26  A   B "C4'"  1 
ATOM   583  O "O4'"  . A   A 1 25  ? 26.408 9.485   27.769 1.00 33.83 ? 26  A   B "O4'"  1 
ATOM   584  C "C3'"  . A   A 1 25  ? 26.148 7.319   28.525 1.00 34.38 ? 26  A   B "C3'"  1 
ATOM   585  O "O3'"  . A   A 1 25  ? 26.779 6.128   28.971 1.00 36.39 ? 26  A   B "O3'"  1 
ATOM   586  C "C2'"  . A   A 1 25  ? 25.840 8.241   29.692 1.00 31.35 ? 26  A   B "C2'"  1 
ATOM   587  O "O2'"  . A   A 1 25  ? 26.926 8.408   30.582 1.00 31.91 ? 26  A   B "O2'"  1 
ATOM   588  C "C1'"  . A   A 1 25  ? 25.625 9.542   28.955 1.00 32.41 ? 26  A   B "C1'"  1 
ATOM   589  N N9     . A   A 1 25  ? 24.222 9.717   28.594 1.00 30.61 ? 26  A   B N9     1 
ATOM   590  C C8     . A   A 1 25  ? 23.618 9.553   27.371 1.00 31.77 ? 26  A   B C8     1 
ATOM   591  N N7     . A   A 1 25  ? 22.335 9.850   27.368 1.00 29.22 ? 26  A   B N7     1 
ATOM   592  C C5     . A   A 1 25  ? 22.078 10.215  28.683 1.00 29.78 ? 26  A   B C5     1 
ATOM   593  C C6     . A   A 1 25  ? 20.911 10.636  29.337 1.00 27.48 ? 26  A   B C6     1 
ATOM   594  N N6     . A   A 1 25  ? 19.737 10.768  28.733 1.00 26.30 ? 26  A   B N6     1 
ATOM   595  N N1     . A   A 1 25  ? 20.988 10.909  30.652 1.00 25.67 ? 26  A   B N1     1 
ATOM   596  C C2     . A   A 1 25  ? 22.165 10.763  31.265 1.00 29.29 ? 26  A   B C2     1 
ATOM   597  N N3     . A   A 1 25  ? 23.341 10.374  30.769 1.00 30.52 ? 26  A   B N3     1 
ATOM   598  C C4     . A   A 1 25  ? 23.227 10.118  29.452 1.00 31.04 ? 26  A   B C4     1 
ATOM   599  H "HO2'" . A   A 1 25  ? 26.642 8.988   31.288 1.00 20.00 ? 26  A   B "HO2'" 1 
ATOM   600  H H61    . A   A 1 25  ? 19.654 10.563  27.750 1.00 20.00 ? 26  A   B H61    1 
ATOM   601  H H62    . A   A 1 25  ? 18.941 11.093  29.262 1.00 20.00 ? 26  A   B H62    1 
ATOM   602  P P      . C   A 1 26  ? 25.889 4.815   29.177 1.00 35.43 ? 27  C   B P      1 
ATOM   603  O OP1    . C   A 1 26  ? 26.785 3.736   29.658 1.00 32.72 ? 27  C   B OP1    1 
ATOM   604  O OP2    . C   A 1 26  ? 25.122 4.623   27.916 1.00 31.22 ? 27  C   B OP2    1 
ATOM   605  O "O5'"  . C   A 1 26  ? 24.862 5.231   30.319 1.00 36.92 ? 27  C   B "O5'"  1 
ATOM   606  C "C5'"  . C   A 1 26  ? 25.304 5.634   31.611 1.00 44.02 ? 27  C   B "C5'"  1 
ATOM   607  C "C4'"  . C   A 1 26  ? 24.116 6.024   32.461 1.00 45.48 ? 27  C   B "C4'"  1 
ATOM   608  O "O4'"  . C   A 1 26  ? 23.513 7.235   31.918 1.00 45.67 ? 27  C   B "O4'"  1 
ATOM   609  C "C3'"  . C   A 1 26  ? 22.935 5.060   32.465 1.00 50.32 ? 27  C   B "C3'"  1 
ATOM   610  O "O3'"  . C   A 1 26  ? 23.128 3.950   33.332 1.00 57.43 ? 27  C   B "O3'"  1 
ATOM   611  C "C2'"  . C   A 1 26  ? 21.797 5.952   32.941 1.00 43.89 ? 27  C   B "C2'"  1 
ATOM   612  O "O2'"  . C   A 1 26  ? 21.796 6.205   34.330 1.00 43.26 ? 27  C   B "O2'"  1 
ATOM   613  C "C1'"  . C   A 1 26  ? 22.119 7.238   32.192 1.00 42.54 ? 27  C   B "C1'"  1 
ATOM   614  N N1     . C   A 1 26  ? 21.384 7.241   30.933 1.00 38.33 ? 27  C   B N1     1 
ATOM   615  C C2     . C   A 1 26  ? 20.070 7.643   30.956 1.00 36.91 ? 27  C   B C2     1 
ATOM   616  O O2     . C   A 1 26  ? 19.570 7.943   32.037 1.00 39.64 ? 27  C   B O2     1 
ATOM   617  N N3     . C   A 1 26  ? 19.367 7.694   29.812 1.00 34.19 ? 27  C   B N3     1 
ATOM   618  C C4     . C   A 1 26  ? 19.943 7.341   28.670 1.00 36.11 ? 27  C   B C4     1 
ATOM   619  N N4     . C   A 1 26  ? 19.226 7.429   27.559 1.00 38.43 ? 27  C   B N4     1 
ATOM   620  C C5     . C   A 1 26  ? 21.292 6.894   28.621 1.00 39.38 ? 27  C   B C5     1 
ATOM   621  C C6     . C   A 1 26  ? 21.976 6.859   29.766 1.00 37.31 ? 27  C   B C6     1 
ATOM   622  H "HO2'" . C   A 1 26  ? 21.058 6.788   34.511 1.00 20.00 ? 27  C   B "HO2'" 1 
ATOM   623  H H41    . C   A 1 26  ? 19.630 7.162   26.674 1.00 20.00 ? 27  C   B H41    1 
ATOM   624  H H42    . C   A 1 26  ? 18.262 7.723   27.600 1.00 20.00 ? 27  C   B H42    1 
ATOM   625  P P      . C   A 1 27  ? 22.510 2.513   32.933 1.00 60.59 ? 28  C   B P      1 
ATOM   626  O OP1    . C   A 1 27  ? 23.283 1.487   33.680 1.00 60.53 ? 28  C   B OP1    1 
ATOM   627  O OP2    . C   A 1 27  ? 22.416 2.424   31.440 1.00 60.63 ? 28  C   B OP2    1 
ATOM   628  O "O5'"  . C   A 1 27  ? 21.030 2.556   33.520 1.00 61.31 ? 28  C   B "O5'"  1 
ATOM   629  C "C5'"  . C   A 1 27  ? 20.813 2.658   34.921 1.00 60.96 ? 28  C   B "C5'"  1 
ATOM   630  C "C4'"  . C   A 1 27  ? 19.372 2.989   35.183 1.00 57.13 ? 28  C   B "C4'"  1 
ATOM   631  O "O4'"  . C   A 1 27  ? 19.031 4.201   34.463 1.00 56.15 ? 28  C   B "O4'"  1 
ATOM   632  C "C3'"  . C   A 1 27  ? 18.391 1.961   34.648 1.00 57.72 ? 28  C   B "C3'"  1 
ATOM   633  O "O3'"  . C   A 1 27  ? 18.219 0.896   35.578 1.00 57.28 ? 28  C   B "O3'"  1 
ATOM   634  C "C2'"  . C   A 1 27  ? 17.124 2.788   34.454 1.00 54.18 ? 28  C   B "C2'"  1 
ATOM   635  O "O2'"  . C   A 1 27  ? 16.379 3.014   35.631 1.00 53.47 ? 28  C   B "O2'"  1 
ATOM   636  C "C1'"  . C   A 1 27  ? 17.705 4.109   33.965 1.00 53.89 ? 28  C   B "C1'"  1 
ATOM   637  N N1     . C   A 1 27  ? 17.744 4.191   32.499 1.00 52.52 ? 28  C   B N1     1 
ATOM   638  C C2     . C   A 1 27  ? 16.577 4.531   31.824 1.00 52.23 ? 28  C   B C2     1 
ATOM   639  O O2     . C   A 1 27  ? 15.548 4.743   32.480 1.00 51.72 ? 28  C   B O2     1 
ATOM   640  N N3     . C   A 1 27  ? 16.591 4.615   30.479 1.00 52.23 ? 28  C   B N3     1 
ATOM   641  C C4     . C   A 1 27  ? 17.723 4.375   29.807 1.00 49.98 ? 28  C   B C4     1 
ATOM   642  N N4     . C   A 1 27  ? 17.698 4.480   28.478 1.00 51.62 ? 28  C   B N4     1 
ATOM   643  C C5     . C   A 1 27  ? 18.929 4.018   30.475 1.00 49.67 ? 28  C   B C5     1 
ATOM   644  C C6     . C   A 1 27  ? 18.897 3.939   31.809 1.00 48.72 ? 28  C   B C6     1 
ATOM   645  H "HO2'" . C   A 1 27  ? 15.618 3.536   35.377 1.00 20.00 ? 28  C   B "HO2'" 1 
ATOM   646  H H41    . C   A 1 27  ? 18.538 4.334   27.938 1.00 20.00 ? 28  C   B H41    1 
ATOM   647  H H42    . C   A 1 27  ? 16.849 4.756   28.009 1.00 20.00 ? 28  C   B H42    1 
ATOM   648  P P      . G   A 1 28  ? 18.046 -0.609  35.033 1.00 59.04 ? 29  G   B P      1 
ATOM   649  O OP1    . G   A 1 28  ? 16.955 -1.250  35.811 1.00 56.13 ? 29  G   B OP1    1 
ATOM   650  O OP2    . G   A 1 28  ? 19.400 -1.232  35.008 1.00 55.09 ? 29  G   B OP2    1 
ATOM   651  O "O5'"  . G   A 1 28  ? 17.526 -0.439  33.538 1.00 59.53 ? 29  G   B "O5'"  1 
ATOM   652  C "C5'"  . G   A 1 28  ? 16.513 -1.287  33.014 1.00 62.58 ? 29  G   B "C5'"  1 
ATOM   653  C "C4'"  . G   A 1 28  ? 15.152 -0.819  33.481 1.00 62.70 ? 29  G   B "C4'"  1 
ATOM   654  O "O4'"  . G   A 1 28  ? 15.093 0.631   33.416 1.00 62.41 ? 29  G   B "O4'"  1 
ATOM   655  C "C3'"  . G   A 1 28  ? 13.996 -1.313  32.621 1.00 63.49 ? 29  G   B "C3'"  1 
ATOM   656  O "O3'"  . G   A 1 28  ? 13.487 -2.556  33.079 1.00 66.01 ? 29  G   B "O3'"  1 
ATOM   657  C "C2'"  . G   A 1 28  ? 13.007 -0.163  32.716 1.00 61.16 ? 29  G   B "C2'"  1 
ATOM   658  O "O2'"  . G   A 1 28  ? 12.272 -0.128  33.925 1.00 57.76 ? 29  G   B "O2'"  1 
ATOM   659  C "C1'"  . G   A 1 28  ? 13.975 1.019   32.641 1.00 61.71 ? 29  G   B "C1'"  1 
ATOM   660  N N9     . G   A 1 28  ? 14.465 1.213   31.278 1.00 59.99 ? 29  G   B N9     1 
ATOM   661  C C8     . G   A 1 28  ? 15.771 1.182   30.859 1.00 60.73 ? 29  G   B C8     1 
ATOM   662  N N7     . G   A 1 28  ? 15.905 1.365   29.574 1.00 59.67 ? 29  G   B N7     1 
ATOM   663  C C5     . G   A 1 28  ? 14.604 1.532   29.119 1.00 61.95 ? 29  G   B C5     1 
ATOM   664  C C6     . G   A 1 28  ? 14.123 1.767   27.820 1.00 64.28 ? 29  G   B C6     1 
ATOM   665  O O6     . G   A 1 28  ? 14.765 1.876   26.772 1.00 65.25 ? 29  G   B O6     1 
ATOM   666  N N1     . G   A 1 28  ? 12.735 1.877   27.801 1.00 63.94 ? 29  G   B N1     1 
ATOM   667  C C2     . G   A 1 28  ? 11.920 1.771   28.901 1.00 64.37 ? 29  G   B C2     1 
ATOM   668  N N2     . G   A 1 28  ? 10.608 1.906   28.684 1.00 65.19 ? 29  G   B N2     1 
ATOM   669  N N3     . G   A 1 28  ? 12.359 1.548   30.119 1.00 63.39 ? 29  G   B N3     1 
ATOM   670  C C4     . G   A 1 28  ? 13.701 1.443   30.159 1.00 61.05 ? 29  G   B C4     1 
ATOM   671  H "HO2'" . G   A 1 28  ? 11.682 0.625   33.870 1.00 20.00 ? 29  G   B "HO2'" 1 
ATOM   672  H H1     . G   A 1 28  ? 12.299 2.048   26.913 1.00 20.00 ? 29  G   B H1     1 
ATOM   673  H H21    . G   A 1 28  ? 9.961  1.842   29.459 1.00 20.00 ? 29  G   B H21    1 
ATOM   674  H H22    . G   A 1 28  ? 10.264 2.074   27.751 1.00 20.00 ? 29  G   B H22    1 
ATOM   675  P P      . G   A 1 29  ? 13.991 -3.913  32.386 1.00 64.60 ? 30  G   B P      1 
ATOM   676  O OP1    . G   A 1 29  ? 14.706 -4.727  33.408 1.00 62.22 ? 30  G   B OP1    1 
ATOM   677  O OP2    . G   A 1 29  ? 14.683 -3.549  31.117 1.00 63.30 ? 30  G   B OP2    1 
ATOM   678  O "O5'"  . G   A 1 29  ? 12.648 -4.660  31.982 1.00 63.86 ? 30  G   B "O5'"  1 
ATOM   679  C "C5'"  . G   A 1 29  ? 11.384 -4.107  32.300 1.00 63.65 ? 30  G   B "C5'"  1 
ATOM   680  C "C4'"  . G   A 1 29  ? 10.653 -3.741  31.034 1.00 63.55 ? 30  G   B "C4'"  1 
ATOM   681  O "O4'"  . G   A 1 29  ? 11.037 -2.409  30.586 1.00 63.53 ? 30  G   B "O4'"  1 
ATOM   682  C "C3'"  . G   A 1 29  ? 10.948 -4.586  29.806 1.00 62.00 ? 30  G   B "C3'"  1 
ATOM   683  O "O3'"  . G   A 1 29  ? 10.313 -5.853  29.779 1.00 61.33 ? 30  G   B "O3'"  1 
ATOM   684  C "C2'"  . G   A 1 29  ? 10.389 -3.709  28.698 1.00 61.99 ? 30  G   B "C2'"  1 
ATOM   685  O "O2'"  . G   A 1 29  ? 8.982  -3.841  28.583 1.00 60.92 ? 30  G   B "O2'"  1 
ATOM   686  C "C1'"  . G   A 1 29  ? 10.814 -2.313  29.177 1.00 61.80 ? 30  G   B "C1'"  1 
ATOM   687  N N9     . G   A 1 29  ? 12.049 -1.909  28.507 1.00 59.08 ? 30  G   B N9     1 
ATOM   688  C C8     . G   A 1 29  ? 13.313 -1.806  29.042 1.00 57.87 ? 30  G   B C8     1 
ATOM   689  N N7     . G   A 1 29  ? 14.221 -1.493  28.155 1.00 55.47 ? 30  G   B N7     1 
ATOM   690  C C5     . G   A 1 29  ? 13.512 -1.366  26.963 1.00 57.19 ? 30  G   B C5     1 
ATOM   691  C C6     . G   A 1 29  ? 13.963 -1.052  25.653 1.00 57.85 ? 30  G   B C6     1 
ATOM   692  O O6     . G   A 1 29  ? 15.113 -0.822  25.267 1.00 58.21 ? 30  G   B O6     1 
ATOM   693  N N1     . G   A 1 29  ? 12.908 -1.023  24.745 1.00 56.64 ? 30  G   B N1     1 
ATOM   694  C C2     . G   A 1 29  ? 11.594 -1.263  25.057 1.00 56.05 ? 30  G   B C2     1 
ATOM   695  N N2     . G   A 1 29  ? 10.715 -1.182  24.051 1.00 57.62 ? 30  G   B N2     1 
ATOM   696  N N3     . G   A 1 29  ? 11.165 -1.560  26.269 1.00 57.23 ? 30  G   B N3     1 
ATOM   697  C C4     . G   A 1 29  ? 12.173 -1.596  27.168 1.00 57.08 ? 30  G   B C4     1 
ATOM   698  H "HO2'" . G   A 1 29  ? 8.696  -3.272  27.871 1.00 20.00 ? 30  G   B "HO2'" 1 
ATOM   699  H H1     . G   A 1 29  ? 13.133 -0.800  23.786 1.00 20.00 ? 30  G   B H1     1 
ATOM   700  H H21    . G   A 1 29  ? 9.733  -1.337  24.229 1.00 20.00 ? 30  G   B H21    1 
ATOM   701  H H22    . G   A 1 29  ? 11.023 -0.947  23.117 1.00 20.00 ? 30  G   B H22    1 
ATOM   702  P P      . A   A 1 30  ? 10.690 -6.884  28.603 1.00 63.17 ? 31  A   B P      1 
ATOM   703  O OP1    . A   A 1 30  ? 9.923  -8.142  28.782 1.00 62.07 ? 31  A   B OP1    1 
ATOM   704  O OP2    . A   A 1 30  ? 12.175 -6.943  28.541 1.00 61.26 ? 31  A   B OP2    1 
ATOM   705  O "O5'"  . A   A 1 30  ? 10.173 -6.154  27.284 1.00 63.89 ? 31  A   B "O5'"  1 
ATOM   706  C "C5'"  . A   A 1 30  ? 8.800  -6.194  26.902 1.00 63.16 ? 31  A   B "C5'"  1 
ATOM   707  C "C4'"  . A   A 1 30  ? 8.685  -6.105  25.402 1.00 62.28 ? 31  A   B "C4'"  1 
ATOM   708  O "O4'"  . A   A 1 30  ? 9.126  -4.790  24.954 1.00 61.06 ? 31  A   B "O4'"  1 
ATOM   709  C "C3'"  . A   A 1 30  ? 9.601  -7.046  24.645 1.00 64.53 ? 31  A   B "C3'"  1 
ATOM   710  O "O3'"  . A   A 1 30  ? 9.111  -8.363  24.519 1.00 66.83 ? 31  A   B "O3'"  1 
ATOM   711  C "C2'"  . A   A 1 30  ? 9.706  -6.363  23.297 1.00 61.00 ? 31  A   B "C2'"  1 
ATOM   712  O "O2'"  . A   A 1 30  ? 8.535  -6.532  22.527 1.00 57.94 ? 31  A   B "O2'"  1 
ATOM   713  C "C1'"  . A   A 1 30  ? 9.874  -4.913  23.741 1.00 61.04 ? 31  A   B "C1'"  1 
ATOM   714  N N9     . A   A 1 30  ? 11.282 -4.594  24.025 1.00 59.07 ? 31  A   B N9     1 
ATOM   715  C C8     . A   A 1 30  ? 11.918 -4.643  25.247 1.00 59.70 ? 31  A   B C8     1 
ATOM   716  N N7     . A   A 1 30  ? 13.181 -4.293  25.206 1.00 59.51 ? 31  A   B N7     1 
ATOM   717  C C5     . A   A 1 30  ? 13.400 -3.993  23.867 1.00 60.15 ? 31  A   B C5     1 
ATOM   718  C C6     . A   A 1 30  ? 14.541 -3.562  23.179 1.00 61.39 ? 31  A   B C6     1 
ATOM   719  N N6     . A   A 1 30  ? 15.714 -3.327  23.770 1.00 64.35 ? 31  A   B N6     1 
ATOM   720  N N1     . A   A 1 30  ? 14.438 -3.366  21.845 1.00 63.19 ? 31  A   B N1     1 
ATOM   721  C C2     . A   A 1 30  ? 13.256 -3.590  21.259 1.00 62.36 ? 31  A   B C2     1 
ATOM   722  N N3     . A   A 1 30  ? 12.105 -3.991  21.802 1.00 62.82 ? 31  A   B N3     1 
ATOM   723  C C4     . A   A 1 30  ? 12.242 -4.181  23.128 1.00 59.30 ? 31  A   B C4     1 
ATOM   724  H "HO2'" . A   A 1 30  ? 8.684  -6.070  21.702 1.00 20.00 ? 31  A   B "HO2'" 1 
ATOM   725  H H61    . A   A 1 30  ? 15.814 -3.465  24.766 1.00 20.00 ? 31  A   B H61    1 
ATOM   726  H H62    . A   A 1 30  ? 16.509 -3.014  23.230 1.00 20.00 ? 31  A   B H62    1 
ATOM   727  P P      . U   A 1 31  ? 10.090 -9.503  23.946 1.00 70.04 ? 32  U   B P      1 
ATOM   728  O OP1    . U   A 1 31  ? 9.592  -10.840 24.365 1.00 70.73 ? 32  U   B OP1    1 
ATOM   729  O OP2    . U   A 1 31  ? 11.494 -9.101  24.277 1.00 70.63 ? 32  U   B OP2    1 
ATOM   730  O "O5'"  . U   A 1 31  ? 9.919  -9.387  22.363 1.00 71.37 ? 32  U   B "O5'"  1 
ATOM   731  C "C5'"  . U   A 1 31  ? 10.856 -10.009 21.506 1.00 70.84 ? 32  U   B "C5'"  1 
ATOM   732  C "C4'"  . U   A 1 31  ? 10.932 -9.274  20.196 1.00 67.91 ? 32  U   B "C4'"  1 
ATOM   733  O "O4'"  . U   A 1 31  ? 11.060 -7.840  20.409 1.00 67.00 ? 32  U   B "O4'"  1 
ATOM   734  C "C3'"  . U   A 1 31  ? 12.168 -9.658  19.413 1.00 69.22 ? 32  U   B "C3'"  1 
ATOM   735  O "O3'"  . U   A 1 31  ? 11.938 -10.847 18.687 1.00 72.10 ? 32  U   B "O3'"  1 
ATOM   736  C "C2'"  . U   A 1 31  ? 12.424 -8.422  18.568 1.00 66.40 ? 32  U   B "C2'"  1 
ATOM   737  O "O2'"  . U   A 1 31  ? 11.567 -8.330  17.446 1.00 66.68 ? 32  U   B "O2'"  1 
ATOM   738  C "C1'"  . U   A 1 31  ? 12.096 -7.320  19.582 1.00 64.37 ? 32  U   B "C1'"  1 
ATOM   739  N N1     . U   A 1 31  ? 13.237 -6.976  20.448 1.00 59.58 ? 32  U   B N1     1 
ATOM   740  C C2     . U   A 1 31  ? 14.387 -6.451  19.863 1.00 57.26 ? 32  U   B C2     1 
ATOM   741  O O2     . U   A 1 31  ? 14.510 -6.283  18.660 1.00 54.72 ? 32  U   B O2     1 
ATOM   742  N N3     . U   A 1 31  ? 15.391 -6.131  20.743 1.00 53.29 ? 32  U   B N3     1 
ATOM   743  C C4     . U   A 1 31  ? 15.378 -6.285  22.111 1.00 54.11 ? 32  U   B C4     1 
ATOM   744  O O4     . U   A 1 31  ? 16.364 -5.938  22.762 1.00 53.23 ? 32  U   B O4     1 
ATOM   745  C C5     . U   A 1 31  ? 14.172 -6.839  22.642 1.00 54.12 ? 32  U   B C5     1 
ATOM   746  C C6     . U   A 1 31  ? 13.166 -7.160  21.815 1.00 55.97 ? 32  U   B C6     1 
ATOM   747  H "HO2'" . U   A 1 31  ? 11.797 -7.530  16.975 1.00 20.00 ? 32  U   B "HO2'" 1 
ATOM   748  H H3     . U   A 1 31  ? 16.227 -5.724  20.350 1.00 20.00 ? 32  U   B H3     1 
ATOM   749  P P      . U   A 1 32  ? 12.871 -12.118 18.969 1.00 73.11 ? 33  U   B P      1 
ATOM   750  O OP1    . U   A 1 32  ? 12.413 -13.245 18.107 1.00 72.35 ? 33  U   B OP1    1 
ATOM   751  O OP2    . U   A 1 32  ? 12.944 -12.292 20.446 1.00 71.43 ? 33  U   B OP2    1 
ATOM   752  O "O5'"  . U   A 1 32  ? 14.299 -11.646 18.456 1.00 71.30 ? 33  U   B "O5'"  1 
ATOM   753  C "C5'"  . U   A 1 32  ? 14.467 -11.182 17.125 1.00 70.89 ? 33  U   B "C5'"  1 
ATOM   754  C "C4'"  . U   A 1 32  ? 15.869 -10.697 16.939 1.00 66.03 ? 33  U   B "C4'"  1 
ATOM   755  O "O4'"  . U   A 1 32  ? 16.062 -9.460  17.671 1.00 64.32 ? 33  U   B "O4'"  1 
ATOM   756  C "C3'"  . U   A 1 32  ? 16.901 -11.640 17.522 1.00 64.45 ? 33  U   B "C3'"  1 
ATOM   757  O "O3'"  . U   A 1 32  ? 17.189 -12.671 16.590 1.00 62.52 ? 33  U   B "O3'"  1 
ATOM   758  C "C2'"  . U   A 1 32  ? 18.085 -10.714 17.756 1.00 61.89 ? 33  U   B "C2'"  1 
ATOM   759  O "O2'"  . U   A 1 32  ? 18.807 -10.472 16.567 1.00 58.26 ? 33  U   B "O2'"  1 
ATOM   760  C "C1'"  . U   A 1 32  ? 17.379 -9.429  18.194 1.00 62.70 ? 33  U   B "C1'"  1 
ATOM   761  N N1     . U   A 1 32  ? 17.298 -9.252  19.653 1.00 59.70 ? 33  U   B N1     1 
ATOM   762  C C2     . U   A 1 32  ? 18.483 -9.052  20.338 1.00 59.24 ? 33  U   B C2     1 
ATOM   763  O O2     . U   A 1 32  ? 19.578 -9.044  19.789 1.00 58.02 ? 33  U   B O2     1 
ATOM   764  N N3     . U   A 1 32  ? 18.341 -8.868  21.695 1.00 58.56 ? 33  U   B N3     1 
ATOM   765  C C4     . U   A 1 32  ? 17.167 -8.873  22.415 1.00 61.86 ? 33  U   B C4     1 
ATOM   766  O O4     . U   A 1 32  ? 17.206 -8.722  23.635 1.00 64.08 ? 33  U   B O4     1 
ATOM   767  C C5     . U   A 1 32  ? 15.989 -9.097  21.635 1.00 59.24 ? 33  U   B C5     1 
ATOM   768  C C6     . U   A 1 32  ? 16.092 -9.275  20.315 1.00 58.76 ? 33  U   B C6     1 
ATOM   769  H "HO2'" . U   A 1 32  ? 19.536 -9.895  16.789 1.00 20.00 ? 33  U   B "HO2'" 1 
ATOM   770  H H3     . U   A 1 32  ? 19.190 -8.713  22.222 1.00 20.00 ? 33  U   B H3     1 
ATOM   771  P P      . C   A 1 33  ? 16.738 -14.179 16.910 1.00 59.76 ? 34  C   B P      1 
ATOM   772  O OP1    . C   A 1 33  ? 15.948 -14.696 15.766 1.00 61.19 ? 34  C   B OP1    1 
ATOM   773  O OP2    . C   A 1 33  ? 16.138 -14.159 18.275 1.00 61.83 ? 34  C   B OP2    1 
ATOM   774  O "O5'"  . C   A 1 33  ? 18.110 -14.981 16.973 1.00 59.77 ? 34  C   B "O5'"  1 
ATOM   775  C "C5'"  . C   A 1 33  ? 19.085 -14.670 17.957 1.00 57.56 ? 34  C   B "C5'"  1 
ATOM   776  C "C4'"  . C   A 1 33  ? 20.470 -14.905 17.412 1.00 54.20 ? 34  C   B "C4'"  1 
ATOM   777  O "O4'"  . C   A 1 33  ? 20.567 -16.168 16.737 1.00 52.95 ? 34  C   B "O4'"  1 
ATOM   778  C "C3'"  . C   A 1 33  ? 21.008 -13.871 16.432 1.00 54.25 ? 34  C   B "C3'"  1 
ATOM   779  O "O3'"  . C   A 1 33  ? 21.928 -13.080 17.186 1.00 55.52 ? 34  C   B "O3'"  1 
ATOM   780  C "C2'"  . C   A 1 33  ? 21.876 -14.680 15.446 1.00 52.60 ? 34  C   B "C2'"  1 
ATOM   781  O "O2'"  . C   A 1 33  ? 23.249 -14.350 15.481 1.00 49.89 ? 34  C   B "O2'"  1 
ATOM   782  C "C1'"  . C   A 1 33  ? 21.724 -16.113 15.959 1.00 50.08 ? 34  C   B "C1'"  1 
ATOM   783  N N1     . C   A 1 33  ? 21.812 -17.255 15.040 1.00 43.75 ? 34  C   B N1     1 
ATOM   784  C C2     . C   A 1 33  ? 23.091 -17.654 14.628 1.00 40.39 ? 34  C   B C2     1 
ATOM   785  O O2     . C   A 1 33  ? 24.088 -17.020 15.038 1.00 37.41 ? 34  C   B O2     1 
ATOM   786  N N3     . C   A 1 33  ? 23.211 -18.722 13.805 1.00 41.19 ? 34  C   B N3     1 
ATOM   787  C C4     . C   A 1 33  ? 22.126 -19.382 13.399 1.00 39.74 ? 34  C   B C4     1 
ATOM   788  N N4     . C   A 1 33  ? 22.303 -20.435 12.599 1.00 35.88 ? 34  C   B N4     1 
ATOM   789  C C5     . C   A 1 33  ? 20.810 -18.985 13.798 1.00 39.79 ? 34  C   B C5     1 
ATOM   790  C C6     . C   A 1 33  ? 20.704 -17.924 14.609 1.00 44.24 ? 34  C   B C6     1 
ATOM   791  H "HO2'" . C   A 1 33  ? 23.687 -14.907 14.841 1.00 20.00 ? 34  C   B "HO2'" 1 
ATOM   792  H H41    . C   A 1 33  ? 21.508 -20.969 12.280 1.00 20.00 ? 34  C   B H41    1 
ATOM   793  H H42    . C   A 1 33  ? 23.236 -20.726 12.338 1.00 20.00 ? 34  C   B H42    1 
ATOM   794  P P      . U   A 1 34  ? 21.623 -11.552 17.529 1.00 54.48 ? 35  U   B P      1 
ATOM   795  O OP1    . U   A 1 34  ? 20.622 -11.480 18.621 1.00 55.85 ? 35  U   B OP1    1 
ATOM   796  O OP2    . U   A 1 34  ? 21.369 -10.844 16.245 1.00 54.45 ? 35  U   B OP2    1 
ATOM   797  O "O5'"  . U   A 1 34  ? 23.012 -11.036 18.124 1.00 55.03 ? 35  U   B "O5'"  1 
ATOM   798  C "C5'"  . U   A 1 34  ? 24.028 -11.946 18.587 1.00 51.34 ? 35  U   B "C5'"  1 
ATOM   799  C "C4'"  . U   A 1 34  ? 25.332 -11.200 18.788 1.00 49.23 ? 35  U   B "C4'"  1 
ATOM   800  O "O4'"  . U   A 1 34  ? 25.717 -10.630 17.528 1.00 48.90 ? 35  U   B "O4'"  1 
ATOM   801  C "C3'"  . U   A 1 34  ? 25.271 -10.051 19.799 1.00 49.19 ? 35  U   B "C3'"  1 
ATOM   802  O "O3'"  . U   A 1 34  ? 26.032 -10.469 20.936 1.00 51.34 ? 35  U   B "O3'"  1 
ATOM   803  C "C2'"  . U   A 1 34  ? 26.058 -8.893  19.158 1.00 47.32 ? 35  U   B "C2'"  1 
ATOM   804  O "O2'"  . U   A 1 34  ? 27.263 -8.555  19.804 1.00 48.67 ? 35  U   B "O2'"  1 
ATOM   805  C "C1'"  . U   A 1 34  ? 26.398 -9.417  17.761 1.00 45.61 ? 35  U   B "C1'"  1 
ATOM   806  N N1     . U   A 1 34  ? 26.185 -8.523  16.619 1.00 38.29 ? 35  U   B N1     1 
ATOM   807  C C2     . U   A 1 34  ? 27.311 -8.065  15.976 1.00 33.61 ? 35  U   B C2     1 
ATOM   808  O O2     . U   A 1 34  ? 28.444 -8.310  16.374 1.00 31.34 ? 35  U   B O2     1 
ATOM   809  N N3     . U   A 1 34  ? 27.069 -7.303  14.867 1.00 32.70 ? 35  U   B N3     1 
ATOM   810  C C4     . U   A 1 34  ? 25.841 -6.931  14.371 1.00 28.68 ? 35  U   B C4     1 
ATOM   811  O O4     . U   A 1 34  ? 25.782 -6.255  13.334 1.00 31.01 ? 35  U   B O4     1 
ATOM   812  C C5     . U   A 1 34  ? 24.723 -7.407  15.122 1.00 31.41 ? 35  U   B C5     1 
ATOM   813  C C6     . U   A 1 34  ? 24.930 -8.171  16.188 1.00 34.12 ? 35  U   B C6     1 
ATOM   814  H "HO2'" . U   A 1 34  ? 27.617 -7.803  19.330 1.00 20.00 ? 35  U   B "HO2'" 1 
ATOM   815  H H3     . U   A 1 34  ? 27.872 -6.954  14.370 1.00 20.00 ? 35  U   B H3     1 
ATOM   816  P P      . G   A 1 35  ? 25.363 -10.616 22.387 1.00 53.90 ? 36  G   B P      1 
ATOM   817  O OP1    . G   A 1 35  ? 26.417 -10.206 23.348 1.00 54.19 ? 36  G   B OP1    1 
ATOM   818  O OP2    . G   A 1 35  ? 24.842 -12.005 22.429 1.00 55.83 ? 36  G   B OP2    1 
ATOM   819  O "O5'"  . G   A 1 35  ? 24.145 -9.575  22.451 1.00 54.50 ? 36  G   B "O5'"  1 
ATOM   820  C "C5'"  . G   A 1 35  ? 24.378 -8.169  22.650 1.00 53.24 ? 36  G   B "C5'"  1 
ATOM   821  C "C4'"  . G   A 1 35  ? 24.222 -7.788  24.119 1.00 51.26 ? 36  G   B "C4'"  1 
ATOM   822  O "O4'"  . G   A 1 35  ? 24.459 -8.934  24.948 1.00 50.16 ? 36  G   B "O4'"  1 
ATOM   823  C "C3'"  . G   A 1 35  ? 25.208 -6.702  24.570 1.00 47.19 ? 36  G   B "C3'"  1 
ATOM   824  O "O3'"  . G   A 1 35  ? 24.602 -5.414  24.782 1.00 44.76 ? 36  G   B "O3'"  1 
ATOM   825  C "C2'"  . G   A 1 35  ? 25.670 -7.134  25.966 1.00 44.83 ? 36  G   B "C2'"  1 
ATOM   826  O "O2'"  . G   A 1 35  ? 25.254 -6.255  26.992 1.00 45.08 ? 36  G   B "O2'"  1 
ATOM   827  C "C1'"  . G   A 1 35  ? 25.035 -8.516  26.150 1.00 47.19 ? 36  G   B "C1'"  1 
ATOM   828  N N9     . G   A 1 35  ? 25.871 -9.583  26.667 1.00 47.18 ? 36  G   B N9     1 
ATOM   829  C C8     . G   A 1 35  ? 27.025 -10.094 26.131 1.00 47.60 ? 36  G   B C8     1 
ATOM   830  N N7     . G   A 1 35  ? 27.505 -11.100 26.813 1.00 47.15 ? 36  G   B N7     1 
ATOM   831  C C5     . G   A 1 35  ? 26.616 -11.251 27.865 1.00 48.18 ? 36  G   B C5     1 
ATOM   832  C C6     . G   A 1 35  ? 26.600 -12.186 28.923 1.00 47.65 ? 36  G   B C6     1 
ATOM   833  O O6     . G   A 1 35  ? 27.380 -13.113 29.134 1.00 47.86 ? 36  G   B O6     1 
ATOM   834  N N1     . G   A 1 35  ? 25.529 -11.972 29.787 1.00 48.48 ? 36  G   B N1     1 
ATOM   835  C C2     . G   A 1 35  ? 24.587 -10.980 29.636 1.00 48.19 ? 36  G   B C2     1 
ATOM   836  N N2     . G   A 1 35  ? 23.627 -10.911 30.577 1.00 49.61 ? 36  G   B N2     1 
ATOM   837  N N3     . G   A 1 35  ? 24.580 -10.112 28.636 1.00 48.65 ? 36  G   B N3     1 
ATOM   838  C C4     . G   A 1 35  ? 25.619 -10.303 27.797 1.00 49.11 ? 36  G   B C4     1 
ATOM   839  H "HO2'" . G   A 1 35  ? 25.608 -6.605  27.810 1.00 20.00 ? 36  G   B "HO2'" 1 
ATOM   840  H H1     . G   A 1 35  ? 25.459 -12.553 30.607 1.00 20.00 ? 36  G   B H1     1 
ATOM   841  H H21    . G   A 1 35  ? 22.913 -10.199 30.522 1.00 20.00 ? 36  G   B H21    1 
ATOM   842  H H22    . G   A 1 35  ? 23.620 -11.553 31.359 1.00 20.00 ? 36  G   B H22    1 
ATOM   843  P P      . A   A 1 36  ? 23.313 -4.939  23.933 1.00 41.53 ? 37  A   B P      1 
ATOM   844  O OP1    . A   A 1 36  ? 22.705 -3.749  24.601 1.00 40.68 ? 37  A   B OP1    1 
ATOM   845  O OP2    . A   A 1 36  ? 22.442 -6.099  23.626 1.00 43.10 ? 37  A   B OP2    1 
ATOM   846  O "O5'"  . A   A 1 36  ? 23.985 -4.423  22.584 1.00 41.83 ? 37  A   B "O5'"  1 
ATOM   847  C "C5'"  . A   A 1 36  ? 25.255 -3.779  22.608 1.00 41.65 ? 37  A   B "C5'"  1 
ATOM   848  C "C4'"  . A   A 1 36  ? 25.697 -3.449  21.212 1.00 41.63 ? 37  A   B "C4'"  1 
ATOM   849  O "O4'"  . A   A 1 36  ? 25.786 -4.691  20.460 1.00 40.09 ? 37  A   B "O4'"  1 
ATOM   850  C "C3'"  . A   A 1 36  ? 24.719 -2.616  20.400 1.00 41.11 ? 37  A   B "C3'"  1 
ATOM   851  O "O3'"  . A   A 1 36  ? 24.799 -1.228  20.689 1.00 39.21 ? 37  A   B "O3'"  1 
ATOM   852  C "C2'"  . A   A 1 36  ? 25.144 -2.943  18.978 1.00 41.33 ? 37  A   B "C2'"  1 
ATOM   853  O "O2'"  . A   A 1 36  ? 26.307 -2.239  18.578 1.00 43.63 ? 37  A   B "O2'"  1 
ATOM   854  C "C1'"  . A   A 1 36  ? 25.435 -4.446  19.103 1.00 42.47 ? 37  A   B "C1'"  1 
ATOM   855  N N9     . A   A 1 36  ? 24.264 -5.263  18.766 1.00 41.76 ? 37  A   B N9     1 
ATOM   856  C C8     . A   A 1 36  ? 23.499 -6.051  19.585 1.00 41.49 ? 37  A   B C8     1 
ATOM   857  N N7     . A   A 1 36  ? 22.457 -6.579  18.990 1.00 43.17 ? 37  A   B N7     1 
ATOM   858  C C5     . A   A 1 36  ? 22.555 -6.122  17.683 1.00 43.38 ? 37  A   B C5     1 
ATOM   859  C C6     . A   A 1 36  ? 21.737 -6.309  16.542 1.00 41.11 ? 37  A   B C6     1 
ATOM   860  N N6     . A   A 1 36  ? 20.600 -7.006  16.542 1.00 40.54 ? 37  A   B N6     1 
ATOM   861  N N1     . A   A 1 36  ? 22.132 -5.732  15.385 1.00 40.87 ? 37  A   B N1     1 
ATOM   862  C C2     . A   A 1 36  ? 23.262 -5.012  15.383 1.00 42.02 ? 37  A   B C2     1 
ATOM   863  N N3     . A   A 1 36  ? 24.102 -4.753  16.387 1.00 43.32 ? 37  A   B N3     1 
ATOM   864  C C4     . A   A 1 36  ? 23.683 -5.339  17.521 1.00 42.76 ? 37  A   B C4     1 
ATOM   865  H "HO2'" . A   A 1 36  ? 26.489 -2.505  17.675 1.00 20.00 ? 37  A   B "HO2'" 1 
ATOM   866  H H61    . A   A 1 36  ? 20.274 -7.435  17.399 1.00 20.00 ? 37  A   B H61    1 
ATOM   867  H H62    . A   A 1 36  ? 20.063 -7.101  15.689 1.00 20.00 ? 37  A   B H62    1 
ATOM   868  P P      . U   A 1 37  ? 23.448 -0.363  20.708 1.00 39.68 ? 38  U   B P      1 
ATOM   869  O OP1    . U   A 1 37  ? 23.790 1.068   20.918 1.00 38.65 ? 38  U   B OP1    1 
ATOM   870  O OP2    . U   A 1 37  ? 22.517 -1.031  21.640 1.00 37.32 ? 38  U   B OP2    1 
ATOM   871  O "O5'"  . U   A 1 37  ? 22.878 -0.529  19.237 1.00 36.89 ? 38  U   B "O5'"  1 
ATOM   872  C "C5'"  . U   A 1 37  ? 23.676 -0.150  18.119 1.00 38.72 ? 38  U   B "C5'"  1 
ATOM   873  C "C4'"  . U   A 1 37  ? 22.987 -0.511  16.836 1.00 37.69 ? 38  U   B "C4'"  1 
ATOM   874  O "O4'"  . U   A 1 37  ? 22.903 -1.949  16.711 1.00 39.05 ? 38  U   B "O4'"  1 
ATOM   875  C "C3'"  . U   A 1 37  ? 21.550 -0.034  16.727 1.00 37.78 ? 38  U   B "C3'"  1 
ATOM   876  O "O3'"  . U   A 1 37  ? 21.507 1.303   16.258 1.00 40.44 ? 38  U   B "O3'"  1 
ATOM   877  C "C2'"  . U   A 1 37  ? 20.961 -0.993  15.706 1.00 39.16 ? 38  U   B "C2'"  1 
ATOM   878  O "O2'"  . U   A 1 37  ? 21.211 -0.570  14.385 1.00 35.91 ? 38  U   B "O2'"  1 
ATOM   879  C "C1'"  . U   A 1 37  ? 21.708 -2.297  16.029 1.00 39.11 ? 38  U   B "C1'"  1 
ATOM   880  N N1     . U   A 1 37  ? 20.928 -3.171  16.909 1.00 37.94 ? 38  U   B N1     1 
ATOM   881  C C2     . U   A 1 37  ? 19.830 -3.818  16.364 1.00 36.95 ? 38  U   B C2     1 
ATOM   882  O O2     . U   A 1 37  ? 19.564 -3.799  15.165 1.00 37.65 ? 38  U   B O2     1 
ATOM   883  N N3     . U   A 1 37  ? 19.062 -4.494  17.268 1.00 38.60 ? 38  U   B N3     1 
ATOM   884  C C4     . U   A 1 37  ? 19.284 -4.610  18.630 1.00 37.90 ? 38  U   B C4     1 
ATOM   885  O O4     . U   A 1 37  ? 18.369 -5.012  19.348 1.00 36.98 ? 38  U   B O4     1 
ATOM   886  C C5     . U   A 1 37  ? 20.491 -3.989  19.092 1.00 37.70 ? 38  U   B C5     1 
ATOM   887  C C6     . U   A 1 37  ? 21.248 -3.307  18.239 1.00 39.80 ? 38  U   B C6     1 
ATOM   888  H "HO2'" . U   A 1 37  ? 20.800 -1.215  13.812 1.00 20.00 ? 38  U   B "HO2'" 1 
ATOM   889  H H3     . U   A 1 37  ? 18.231 -4.946  16.904 1.00 20.00 ? 38  U   B H3     1 
ATOM   890  P P      . U   A 1 38  ? 20.449 2.316   16.894 1.00 45.78 ? 39  U   B P      1 
ATOM   891  O OP1    . U   A 1 38  ? 20.563 3.628   16.207 1.00 45.31 ? 39  U   B OP1    1 
ATOM   892  O OP2    . U   A 1 38  ? 20.612 2.234   18.368 1.00 45.47 ? 39  U   B OP2    1 
ATOM   893  O "O5'"  . U   A 1 38  ? 19.056 1.677   16.494 1.00 49.18 ? 39  U   B "O5'"  1 
ATOM   894  C "C5'"  . U   A 1 38  ? 18.681 1.599   15.128 1.00 53.33 ? 39  U   B "C5'"  1 
ATOM   895  C "C4'"  . U   A 1 38  ? 17.394 0.835   14.986 1.00 55.32 ? 39  U   B "C4'"  1 
ATOM   896  O "O4'"  . U   A 1 38  ? 17.630 -0.560  15.323 1.00 54.17 ? 39  U   B "O4'"  1 
ATOM   897  C "C3'"  . U   A 1 38  ? 16.285 1.276   15.923 1.00 57.25 ? 39  U   B "C3'"  1 
ATOM   898  O "O3'"  . U   A 1 38  ? 15.571 2.390   15.416 1.00 58.57 ? 39  U   B "O3'"  1 
ATOM   899  C "C2'"  . U   A 1 38  ? 15.432 0.025   16.004 1.00 54.66 ? 39  U   B "C2'"  1 
ATOM   900  O "O2'"  . U   A 1 38  ? 14.596 -0.131  14.874 1.00 52.54 ? 39  U   B "O2'"  1 
ATOM   901  C "C1'"  . U   A 1 38  ? 16.517 -1.058  16.039 1.00 53.35 ? 39  U   B "C1'"  1 
ATOM   902  N N1     . U   A 1 38  ? 16.961 -1.367  17.401 1.00 52.39 ? 39  U   B N1     1 
ATOM   903  C C2     . U   A 1 38  ? 16.000 -1.470  18.381 1.00 50.20 ? 39  U   B C2     1 
ATOM   904  O O2     . U   A 1 38  ? 14.825 -1.268  18.165 1.00 48.20 ? 39  U   B O2     1 
ATOM   905  N N3     . U   A 1 38  ? 16.464 -1.801  19.624 1.00 51.55 ? 39  U   B N3     1 
ATOM   906  C C4     . U   A 1 38  ? 17.758 -2.012  19.989 1.00 50.21 ? 39  U   B C4     1 
ATOM   907  O O4     . U   A 1 38  ? 18.011 -2.295  21.159 1.00 50.56 ? 39  U   B O4     1 
ATOM   908  C C5     . U   A 1 38  ? 18.707 -1.863  18.926 1.00 52.17 ? 39  U   B C5     1 
ATOM   909  C C6     . U   A 1 38  ? 18.283 -1.559  17.698 1.00 54.12 ? 39  U   B C6     1 
ATOM   910  H "HO2'" . U   A 1 38  ? 14.109 -0.947  14.993 1.00 20.00 ? 39  U   B "HO2'" 1 
ATOM   911  H H3     . U   A 1 38  ? 15.777 -1.901  20.356 1.00 20.00 ? 39  U   B H3     1 
ATOM   912  P P      . C   A 1 39  ? 14.947 3.455   16.440 1.00 60.17 ? 40  C   B P      1 
ATOM   913  O OP1    . C   A 1 39  ? 14.373 4.570   15.645 1.00 61.69 ? 40  C   B OP1    1 
ATOM   914  O OP2    . C   A 1 39  ? 15.981 3.745   17.463 1.00 62.12 ? 40  C   B OP2    1 
ATOM   915  O "O5'"  . C   A 1 39  ? 13.758 2.665   17.148 1.00 62.46 ? 40  C   B "O5'"  1 
ATOM   916  C "C5'"  . C   A 1 39  ? 12.592 2.280   16.411 1.00 61.83 ? 40  C   B "C5'"  1 
ATOM   917  C "C4'"  . C   A 1 39  ? 11.511 1.801   17.352 1.00 59.45 ? 40  C   B "C4'"  1 
ATOM   918  O "O4'"  . C   A 1 39  ? 11.920 0.538   17.939 1.00 55.97 ? 40  C   B "O4'"  1 
ATOM   919  C "C3'"  . C   A 1 39  ? 11.233 2.719   18.540 1.00 59.69 ? 40  C   B "C3'"  1 
ATOM   920  O "O3'"  . C   A 1 39  ? 10.262 3.698   18.162 1.00 62.06 ? 40  C   B "O3'"  1 
ATOM   921  C "C2'"  . C   A 1 39  ? 10.712 1.747   19.593 1.00 54.58 ? 40  C   B "C2'"  1 
ATOM   922  O "O2'"  . C   A 1 39  ? 9.363  1.404   19.384 1.00 51.58 ? 40  C   B "O2'"  1 
ATOM   923  C "C1'"  . C   A 1 39  ? 11.550 0.500   19.306 1.00 51.01 ? 40  C   B "C1'"  1 
ATOM   924  N N1     . C   A 1 39  ? 12.772 0.389   20.119 1.00 43.32 ? 40  C   B N1     1 
ATOM   925  C C2     . C   A 1 39  ? 12.696 -0.231  21.379 1.00 39.48 ? 40  C   B C2     1 
ATOM   926  O O2     . C   A 1 39  ? 11.601 -0.643  21.783 1.00 39.79 ? 40  C   B O2     1 
ATOM   927  N N3     . C   A 1 39  ? 13.822 -0.363  22.119 1.00 37.26 ? 40  C   B N3     1 
ATOM   928  C C4     . C   A 1 39  ? 14.990 0.088   21.645 1.00 37.72 ? 40  C   B C4     1 
ATOM   929  N N4     . C   A 1 39  ? 16.082 -0.094  22.391 1.00 36.40 ? 40  C   B N4     1 
ATOM   930  C C5     . C   A 1 39  ? 15.090 0.735   20.377 1.00 39.72 ? 40  C   B C5     1 
ATOM   931  C C6     . C   A 1 39  ? 13.969 0.866   19.656 1.00 41.63 ? 40  C   B C6     1 
ATOM   932  H "HO2'" . C   A 1 39  ? 9.100  0.789   20.068 1.00 20.00 ? 40  C   B "HO2'" 1 
ATOM   933  H H41    . C   A 1 39  ? 16.982 0.236   22.060 1.00 20.00 ? 40  C   B H41    1 
ATOM   934  H H42    . C   A 1 39  ? 16.007 -0.542  23.295 1.00 20.00 ? 40  C   B H42    1 
ATOM   935  P P      . C   A 1 40  ? 9.871  4.883   19.184 1.00 66.15 ? 41  C   B P      1 
ATOM   936  O OP1    . C   A 1 40  ? 8.643  5.556   18.665 1.00 65.91 ? 41  C   B OP1    1 
ATOM   937  O OP2    . C   A 1 40  ? 11.090 5.696   19.455 1.00 66.20 ? 41  C   B OP2    1 
ATOM   938  O "O5'"  . C   A 1 40  ? 9.463  4.112   20.514 1.00 67.98 ? 41  C   B "O5'"  1 
ATOM   939  C "C5'"  . C   A 1 40  ? 8.279  3.318   20.564 1.00 69.87 ? 41  C   B "C5'"  1 
ATOM   940  C "C4'"  . C   A 1 40  ? 7.928  3.018   21.993 1.00 67.22 ? 41  C   B "C4'"  1 
ATOM   941  O "O4'"  . C   A 1 40  ? 8.725  1.902   22.470 1.00 65.82 ? 41  C   B "O4'"  1 
ATOM   942  C "C3'"  . C   A 1 40  ? 8.287  4.161   22.915 1.00 68.84 ? 41  C   B "C3'"  1 
ATOM   943  O "O3'"  . C   A 1 40  ? 7.260  5.133   22.904 1.00 73.83 ? 41  C   B "O3'"  1 
ATOM   944  C "C2'"  . C   A 1 40  ? 8.504  3.465   24.251 1.00 63.72 ? 41  C   B "C2'"  1 
ATOM   945  O "O2'"  . C   A 1 40  ? 7.313  3.208   24.966 1.00 63.42 ? 41  C   B "O2'"  1 
ATOM   946  C "C1'"  . C   A 1 40  ? 9.162  2.160   23.795 1.00 63.41 ? 41  C   B "C1'"  1 
ATOM   947  N N1     . C   A 1 40  ? 10.625 2.270   23.763 1.00 55.48 ? 41  C   B N1     1 
ATOM   948  C C2     . C   A 1 40  ? 11.350 2.030   24.939 1.00 52.06 ? 41  C   B C2     1 
ATOM   949  O O2     . C   A 1 40  ? 10.739 1.714   25.982 1.00 49.60 ? 41  C   B O2     1 
ATOM   950  N N3     . C   A 1 40  ? 12.697 2.151   24.918 1.00 50.39 ? 41  C   B N3     1 
ATOM   951  C C4     . C   A 1 40  ? 13.322 2.504   23.789 1.00 49.43 ? 41  C   B C4     1 
ATOM   952  N N4     . C   A 1 40  ? 14.657 2.645   23.824 1.00 47.12 ? 41  C   B N4     1 
ATOM   953  C C5     . C   A 1 40  ? 12.605 2.743   22.574 1.00 51.51 ? 41  C   B C5     1 
ATOM   954  C C6     . C   A 1 40  ? 11.273 2.611   22.608 1.00 52.82 ? 41  C   B C6     1 
ATOM   955  H "HO2'" . C   A 1 40  ? 7.571  2.783   25.784 1.00 20.00 ? 41  C   B "HO2'" 1 
ATOM   956  H H41    . C   A 1 40  ? 15.161 2.935   22.995 1.00 20.00 ? 41  C   B H41    1 
ATOM   957  H H42    . C   A 1 40  ? 15.158 2.484   24.690 1.00 20.00 ? 41  C   B H42    1 
ATOM   958  P P      . G   A 1 41  ? 7.654  6.681   22.959 1.00 76.31 ? 42  G   B P      1 
ATOM   959  O OP1    . G   A 1 41  ? 6.540  7.474   22.368 1.00 77.09 ? 42  G   B OP1    1 
ATOM   960  O OP2    . G   A 1 41  ? 9.022  6.792   22.378 1.00 79.27 ? 42  G   B OP2    1 
ATOM   961  O "O5'"  . G   A 1 41  ? 7.753  6.951   24.526 1.00 76.77 ? 42  G   B "O5'"  1 
ATOM   962  C "C5'"  . G   A 1 41  ? 6.813  6.348   25.401 1.00 75.09 ? 42  G   B "C5'"  1 
ATOM   963  C "C4'"  . G   A 1 41  ? 7.455  6.012   26.723 1.00 69.60 ? 42  G   B "C4'"  1 
ATOM   964  O "O4'"  . G   A 1 41  ? 8.479  4.997   26.565 1.00 71.06 ? 42  G   B "O4'"  1 
ATOM   965  C "C3'"  . G   A 1 41  ? 8.218  7.127   27.403 1.00 69.65 ? 42  G   B "C3'"  1 
ATOM   966  O "O3'"  . G   A 1 41  ? 7.351  8.073   28.008 1.00 66.61 ? 42  G   B "O3'"  1 
ATOM   967  C "C2'"  . G   A 1 41  ? 9.028  6.357   28.441 1.00 66.93 ? 42  G   B "C2'"  1 
ATOM   968  O "O2'"  . G   A 1 41  ? 8.307  6.059   29.622 1.00 66.66 ? 42  G   B "O2'"  1 
ATOM   969  C "C1'"  . G   A 1 41  ? 9.356  5.071   27.677 1.00 69.53 ? 42  G   B "C1'"  1 
ATOM   970  N N9     . G   A 1 41  ? 10.736 5.080   27.212 1.00 67.25 ? 42  G   B N9     1 
ATOM   971  C C8     . G   A 1 41  ? 11.207 5.178   25.926 1.00 65.19 ? 42  G   B C8     1 
ATOM   972  N N7     . G   A 1 41  ? 12.513 5.181   25.857 1.00 64.75 ? 42  G   B N7     1 
ATOM   973  C C5     . G   A 1 41  ? 12.922 5.068   27.184 1.00 65.12 ? 42  G   B C5     1 
ATOM   974  C C6     . G   A 1 41  ? 14.234 5.013   27.751 1.00 65.80 ? 42  G   B C6     1 
ATOM   975  O O6     . G   A 1 41  ? 15.328 5.041   27.171 1.00 65.22 ? 42  G   B O6     1 
ATOM   976  N N1     . G   A 1 41  ? 14.186 4.914   29.141 1.00 65.93 ? 42  G   B N1     1 
ATOM   977  C C2     . G   A 1 41  ? 13.031 4.869   29.891 1.00 67.74 ? 42  G   B C2     1 
ATOM   978  N N2     . G   A 1 41  ? 13.189 4.796   31.223 1.00 67.89 ? 42  G   B N2     1 
ATOM   979  N N3     . G   A 1 41  ? 11.814 4.900   29.373 1.00 65.06 ? 42  G   B N3     1 
ATOM   980  C C4     . G   A 1 41  ? 11.834 5.005   28.031 1.00 66.54 ? 42  G   B C4     1 
ATOM   981  H "HO2'" . G   A 1 41  ? 8.904  5.585   30.200 1.00 20.00 ? 42  G   B "HO2'" 1 
ATOM   982  H H1     . G   A 1 41  ? 15.071 4.900   29.637 1.00 20.00 ? 42  G   B H1     1 
ATOM   983  H H21    . G   A 1 41  ? 12.379 4.765   31.826 1.00 20.00 ? 42  G   B H21    1 
ATOM   984  H H22    . G   A 1 41  ? 14.115 4.780   31.630 1.00 20.00 ? 42  G   B H22    1 
ATOM   985  P P      . G   A 1 42  ? 7.905  9.537   28.329 1.00 66.02 ? 43  G   B P      1 
ATOM   986  O OP1    . G   A 1 42  ? 6.799  10.371  28.885 1.00 67.88 ? 43  G   B OP1    1 
ATOM   987  O OP2    . G   A 1 42  ? 8.630  9.990   27.108 1.00 66.59 ? 43  G   B OP2    1 
ATOM   988  O "O5'"  . G   A 1 42  ? 8.971  9.275   29.482 1.00 68.79 ? 43  G   B "O5'"  1 
ATOM   989  C "C5'"  . G   A 1 42  ? 8.582  8.622   30.676 1.00 69.67 ? 43  G   B "C5'"  1 
ATOM   990  C "C4'"  . G   A 1 42  ? 9.689  8.702   31.685 1.00 68.96 ? 43  G   B "C4'"  1 
ATOM   991  O "O4'"  . G   A 1 42  ? 10.781 7.841   31.279 1.00 68.53 ? 43  G   B "O4'"  1 
ATOM   992  C "C3'"  . G   A 1 42  ? 10.326 10.073  31.800 1.00 70.41 ? 43  G   B "C3'"  1 
ATOM   993  O "O3'"  . G   A 1 42  ? 9.563  10.915  32.652 1.00 70.91 ? 43  G   B "O3'"  1 
ATOM   994  C "C2'"  . G   A 1 42  ? 11.685 9.739   32.401 1.00 69.61 ? 43  G   B "C2'"  1 
ATOM   995  O "O2'"  . G   A 1 42  ? 11.622 9.575   33.809 1.00 67.22 ? 43  G   B "O2'"  1 
ATOM   996  C "C1'"  . G   A 1 42  ? 12.000 8.405   31.728 1.00 68.53 ? 43  G   B "C1'"  1 
ATOM   997  N N9     . G   A 1 42  ? 12.917 8.495   30.593 1.00 66.10 ? 43  G   B N9     1 
ATOM   998  C C8     . G   A 1 42  ? 12.599 8.713   29.273 1.00 66.59 ? 43  G   B C8     1 
ATOM   999  N N7     . G   A 1 42  ? 13.644 8.719   28.493 1.00 65.09 ? 43  G   B N7     1 
ATOM   1000 C C5     . G   A 1 42  ? 14.716 8.501   29.348 1.00 64.82 ? 43  G   B C5     1 
ATOM   1001 C C6     . G   A 1 42  ? 16.104 8.400   29.082 1.00 65.71 ? 43  G   B C6     1 
ATOM   1002 O O6     . G   A 1 42  ? 16.684 8.489   27.997 1.00 65.46 ? 43  G   B O6     1 
ATOM   1003 N N1     . G   A 1 42  ? 16.837 8.174   30.240 1.00 66.41 ? 43  G   B N1     1 
ATOM   1004 C C2     . G   A 1 42  ? 16.303 8.065   31.491 1.00 68.03 ? 43  G   B C2     1 
ATOM   1005 N N2     . G   A 1 42  ? 17.170 7.858   32.482 1.00 68.60 ? 43  G   B N2     1 
ATOM   1006 N N3     . G   A 1 42  ? 15.012 8.154   31.761 1.00 66.79 ? 43  G   B N3     1 
ATOM   1007 C C4     . G   A 1 42  ? 14.283 8.373   30.645 1.00 65.97 ? 43  G   B C4     1 
ATOM   1008 H "HO2'" . G   A 1 42  ? 12.510 9.375   34.103 1.00 20.00 ? 43  G   B "HO2'" 1 
ATOM   1009 H H1     . G   A 1 42  ? 17.843 8.099   30.143 1.00 20.00 ? 43  G   B H1     1 
ATOM   1010 H H21    . G   A 1 42  ? 16.846 7.790   33.436 1.00 20.00 ? 43  G   B H21    1 
ATOM   1011 H H22    . G   A 1 42  ? 18.162 7.810   32.290 1.00 20.00 ? 43  G   B H22    1 
ATOM   1012 P P      . C   A 1 43  ? 9.848  12.494  32.675 1.00 74.10 ? 44  C   B P      1 
ATOM   1013 O OP1    . C   A 1 43  ? 8.862  13.159  33.569 1.00 74.27 ? 44  C   B OP1    1 
ATOM   1014 O OP2    . C   A 1 43  ? 9.977  12.939  31.259 1.00 73.47 ? 44  C   B OP2    1 
ATOM   1015 O "O5'"  . C   A 1 43  ? 11.280 12.614  33.357 1.00 75.24 ? 44  C   B "O5'"  1 
ATOM   1016 C "C5'"  . C   A 1 43  ? 12.418 12.918  32.572 1.00 74.84 ? 44  C   B "C5'"  1 
ATOM   1017 C "C4'"  . C   A 1 43  ? 13.671 12.841  33.402 1.00 74.55 ? 44  C   B "C4'"  1 
ATOM   1018 O "O4'"  . C   A 1 43  ? 14.348 11.583  33.123 1.00 72.46 ? 44  C   B "O4'"  1 
ATOM   1019 C "C3'"  . C   A 1 43  ? 14.666 13.935  33.040 1.00 75.16 ? 44  C   B "C3'"  1 
ATOM   1020 O "O3'"  . C   A 1 43  ? 14.495 15.073  33.883 1.00 76.43 ? 44  C   B "O3'"  1 
ATOM   1021 C "C2'"  . C   A 1 43  ? 16.001 13.234  33.244 1.00 72.04 ? 44  C   B "C2'"  1 
ATOM   1022 O "O2'"  . C   A 1 43  ? 16.357 13.143  34.614 1.00 71.78 ? 44  C   B "O2'"  1 
ATOM   1023 C "C1'"  . C   A 1 43  ? 15.674 11.844  32.696 1.00 70.23 ? 44  C   B "C1'"  1 
ATOM   1024 N N1     . C   A 1 43  ? 15.650 11.805  31.222 1.00 64.87 ? 44  C   B N1     1 
ATOM   1025 C C2     . C   A 1 43  ? 16.829 11.526  30.513 1.00 62.83 ? 44  C   B C2     1 
ATOM   1026 O O2     . C   A 1 43  ? 17.875 11.297  31.144 1.00 60.93 ? 44  C   B O2     1 
ATOM   1027 N N3     . C   A 1 43  ? 16.792 11.513  29.163 1.00 60.61 ? 44  C   B N3     1 
ATOM   1028 C C4     . C   A 1 43  ? 15.646 11.758  28.519 1.00 59.65 ? 44  C   B C4     1 
ATOM   1029 N N4     . C   A 1 43  ? 15.652 11.741  27.179 1.00 56.84 ? 44  C   B N4     1 
ATOM   1030 C C5     . C   A 1 43  ? 14.438 12.040  29.222 1.00 60.29 ? 44  C   B C5     1 
ATOM   1031 C C6     . C   A 1 43  ? 14.487 12.050  30.550 1.00 63.26 ? 44  C   B C6     1 
ATOM   1032 H "HO2'" . C   A 1 43  ? 17.211 12.713  34.654 1.00 20.00 ? 44  C   B "HO2'" 1 
ATOM   1033 H H41    . C   A 1 43  ? 14.805 11.933  26.663 1.00 20.00 ? 44  C   B H41    1 
ATOM   1034 H H42    . C   A 1 43  ? 16.510 11.551  26.683 1.00 20.00 ? 44  C   B H42    1 
ATOM   1035 P P      . A   A 1 44  ? 13.279 16.101  33.605 1.00 76.34 ? 45  A   B P      1 
ATOM   1036 O OP1    . A   A 1 44  ? 12.158 15.739  34.521 1.00 77.76 ? 45  A   B OP1    1 
ATOM   1037 O OP2    . A   A 1 44  ? 13.039 16.135  32.133 1.00 77.31 ? 45  A   B OP2    1 
ATOM   1038 O "O5'"  . A   A 1 44  ? 13.868 17.513  34.059 1.00 74.43 ? 45  A   B "O5'"  1 
ATOM   1039 C "C5'"  . A   A 1 44  ? 14.392 17.699  35.377 1.00 68.79 ? 45  A   B "C5'"  1 
ATOM   1040 C "C4'"  . A   A 1 44  ? 14.673 19.164  35.625 1.00 63.00 ? 45  A   B "C4'"  1 
ATOM   1041 O "O4'"  . A   A 1 44  ? 15.697 19.612  34.701 1.00 58.97 ? 45  A   B "O4'"  1 
ATOM   1042 C "C3'"  . A   A 1 44  ? 13.503 20.106  35.379 1.00 62.16 ? 45  A   B "C3'"  1 
ATOM   1043 O "O3'"  . A   A 1 44  ? 12.569 20.126  36.478 1.00 60.53 ? 45  A   B "O3'"  1 
ATOM   1044 C "C2'"  . A   A 1 44  ? 14.161 21.436  35.001 1.00 55.53 ? 45  A   B "C2'"  1 
ATOM   1045 O "O2'"  . A   A 1 44  ? 14.322 22.362  36.059 1.00 53.39 ? 45  A   B "O2'"  1 
ATOM   1046 C "C1'"  . A   A 1 44  ? 15.518 20.985  34.435 1.00 54.61 ? 45  A   B "C1'"  1 
ATOM   1047 N N9     . A   A 1 44  ? 15.751 21.227  33.010 1.00 49.87 ? 45  A   B N9     1 
ATOM   1048 C C8     . A   A 1 44  ? 14.898 21.082  31.947 1.00 49.91 ? 45  A   B C8     1 
ATOM   1049 N N7     . A   A 1 44  ? 15.436 21.421  30.792 1.00 47.04 ? 45  A   B N7     1 
ATOM   1050 C C5     . A   A 1 44  ? 16.730 21.802  31.124 1.00 48.29 ? 45  A   B C5     1 
ATOM   1051 C C6     . A   A 1 44  ? 17.810 22.282  30.352 1.00 47.99 ? 45  A   B C6     1 
ATOM   1052 N N6     . A   A 1 44  ? 17.752 22.486  29.039 1.00 48.41 ? 45  A   B N6     1 
ATOM   1053 N N1     . A   A 1 44  ? 18.962 22.565  30.992 1.00 46.99 ? 45  A   B N1     1 
ATOM   1054 C C2     . A   A 1 44  ? 19.013 22.397  32.316 1.00 49.79 ? 45  A   B C2     1 
ATOM   1055 N N3     . A   A 1 44  ? 18.068 21.966  33.153 1.00 48.61 ? 45  A   B N3     1 
ATOM   1056 C C4     . A   A 1 44  ? 16.937 21.683  32.481 1.00 48.45 ? 45  A   B C4     1 
ATOM   1057 H "HO2'" . A   A 1 44  ? 14.737 23.146  35.704 1.00 20.00 ? 45  A   B "HO2'" 1 
ATOM   1058 H H61    . A   A 1 44  ? 16.885 22.323  28.540 1.00 20.00 ? 45  A   B H61    1 
ATOM   1059 H H62    . A   A 1 44  ? 18.556 22.859  28.553 1.00 20.00 ? 45  A   B H62    1 
ATOM   1060 P P      . U   A 1 45  ? 13.073 20.405  37.996 1.00 60.44 ? 46  U   B P      1 
ATOM   1061 O OP1    . U   A 1 45  ? 14.379 21.121  38.047 1.00 59.95 ? 46  U   B OP1    1 
ATOM   1062 O OP2    . U   A 1 45  ? 12.946 19.096  38.697 1.00 58.99 ? 46  U   B OP2    1 
ATOM   1063 O "O5'"  . U   A 1 45  ? 11.964 21.401  38.580 1.00 64.63 ? 46  U   B "O5'"  1 
ATOM   1064 C "C5'"  . U   A 1 45  ? 10.580 21.277  38.237 1.00 69.00 ? 46  U   B "C5'"  1 
ATOM   1065 C "C4'"  . U   A 1 45  ? 10.014 22.640  37.915 1.00 70.97 ? 46  U   B "C4'"  1 
ATOM   1066 O "O4'"  . U   A 1 45  ? 8.608  22.578  37.577 1.00 72.19 ? 46  U   B "O4'"  1 
ATOM   1067 C "C3'"  . U   A 1 45  ? 10.002 23.631  39.057 1.00 72.22 ? 46  U   B "C3'"  1 
ATOM   1068 O "O3'"  . U   A 1 45  ? 11.299 24.152  39.247 1.00 73.24 ? 46  U   B "O3'"  1 
ATOM   1069 C "C2'"  . U   A 1 45  ? 9.041  24.706  38.552 1.00 70.57 ? 46  U   B "C2'"  1 
ATOM   1070 O "O2'"  . U   A 1 45  ? 9.648  25.702  37.759 1.00 66.82 ? 46  U   B "O2'"  1 
ATOM   1071 C "C1'"  . U   A 1 45  ? 8.056  23.885  37.709 1.00 72.99 ? 46  U   B "C1'"  1 
ATOM   1072 N N1     . U   A 1 45  ? 6.725  23.816  38.326 1.00 72.40 ? 46  U   B N1     1 
ATOM   1073 C C2     . U   A 1 45  ? 5.647  23.482  37.516 1.00 72.49 ? 46  U   B C2     1 
ATOM   1074 O O2     . U   A 1 45  ? 5.770  23.196  36.332 1.00 71.51 ? 46  U   B O2     1 
ATOM   1075 N N3     . U   A 1 45  ? 4.420  23.491  38.142 1.00 74.64 ? 46  U   B N3     1 
ATOM   1076 C C4     . U   A 1 45  ? 4.162  23.797  39.465 1.00 74.41 ? 46  U   B C4     1 
ATOM   1077 O O4     . U   A 1 45  ? 2.995  23.792  39.873 1.00 75.78 ? 46  U   B O4     1 
ATOM   1078 C C5     . U   A 1 45  ? 5.326  24.117  40.242 1.00 75.93 ? 46  U   B C5     1 
ATOM   1079 C C6     . U   A 1 45  ? 6.536  24.109  39.664 1.00 73.44 ? 46  U   B C6     1 
ATOM   1080 H "HO2'" . U   A 1 45  ? 8.963  26.325  37.520 1.00 20.00 ? 46  U   B "HO2'" 1 
ATOM   1081 H H3     . U   A 1 45  ? 3.625  23.236  37.576 1.00 20.00 ? 46  U   B H3     1 
ATOM   1082 P P      . U   A 1 46  ? 12.009 23.989  40.671 1.00 75.00 ? 47  U   B P      1 
ATOM   1083 O OP1    . U   A 1 46  ? 12.317 22.545  40.859 1.00 77.03 ? 47  U   B OP1    1 
ATOM   1084 O OP2    . U   A 1 46  ? 11.177 24.698  41.683 1.00 76.84 ? 47  U   B OP2    1 
ATOM   1085 O "O5'"  . U   A 1 46  ? 13.373 24.803  40.500 1.00 76.00 ? 47  U   B "O5'"  1 
ATOM   1086 C "C5'"  . U   A 1 46  ? 14.489 24.233  39.817 1.00 72.77 ? 47  U   B "C5'"  1 
ATOM   1087 C "C4'"  . U   A 1 46  ? 14.568 24.762  38.405 1.00 69.17 ? 47  U   B "C4'"  1 
ATOM   1088 O "O4'"  . U   A 1 46  ? 13.520 24.192  37.584 1.00 67.88 ? 47  U   B "O4'"  1 
ATOM   1089 C "C3'"  . U   A 1 46  ? 14.390 26.266  38.236 1.00 67.64 ? 47  U   B "C3'"  1 
ATOM   1090 O "O3'"  . U   A 1 46  ? 15.642 26.913  38.442 1.00 62.70 ? 47  U   B "O3'"  1 
ATOM   1091 C "C2'"  . U   A 1 46  ? 13.947 26.408  36.776 1.00 65.08 ? 47  U   B "C2'"  1 
ATOM   1092 O "O2'"  . U   A 1 46  ? 15.003 26.609  35.862 1.00 65.85 ? 47  U   B "O2'"  1 
ATOM   1093 C "C1'"  . U   A 1 46  ? 13.337 25.037  36.476 1.00 64.06 ? 47  U   B "C1'"  1 
ATOM   1094 N N1     . U   A 1 46  ? 11.956 24.963  35.981 1.00 60.70 ? 47  U   B N1     1 
ATOM   1095 C C2     . U   A 1 46  ? 11.304 26.144  35.653 1.00 59.72 ? 47  U   B C2     1 
ATOM   1096 O O2     . U   A 1 46  ? 11.764 27.250  35.875 1.00 58.92 ? 47  U   B O2     1 
ATOM   1097 N N3     . U   A 1 46  ? 10.076 25.981  35.056 1.00 60.00 ? 47  U   B N3     1 
ATOM   1098 C C4     . U   A 1 46  ? 9.433  24.789  34.787 1.00 60.84 ? 47  U   B C4     1 
ATOM   1099 O O4     . U   A 1 46  ? 8.375  24.805  34.143 1.00 58.71 ? 47  U   B O4     1 
ATOM   1100 C C5     . U   A 1 46  ? 10.147 23.616  35.215 1.00 59.75 ? 47  U   B C5     1 
ATOM   1101 C C6     . U   A 1 46  ? 11.353 23.742  35.788 1.00 60.40 ? 47  U   B C6     1 
ATOM   1102 H "HO2'" . U   A 1 46  ? 14.593 26.703  35.003 1.00 20.00 ? 47  U   B "HO2'" 1 
ATOM   1103 H H3     . U   A 1 46  ? 9.591  26.820  34.768 1.00 20.00 ? 47  U   B H3     1 
ATOM   1104 P P      . C   A 1 47  ? 15.716 28.518  38.499 1.00 62.16 ? 48  C   B P      1 
ATOM   1105 O OP1    . C   A 1 47  ? 16.041 28.881  39.904 1.00 64.45 ? 48  C   B OP1    1 
ATOM   1106 O OP2    . C   A 1 47  ? 14.497 29.091  37.847 1.00 62.73 ? 48  C   B OP2    1 
ATOM   1107 O "O5'"  . C   A 1 47  ? 16.970 28.897  37.586 1.00 62.06 ? 48  C   B "O5'"  1 
ATOM   1108 C "C5'"  . C   A 1 47  ? 18.094 28.023  37.451 1.00 57.46 ? 48  C   B "C5'"  1 
ATOM   1109 C "C4'"  . C   A 1 47  ? 18.649 28.139  36.057 1.00 52.03 ? 48  C   B "C4'"  1 
ATOM   1110 O "O4'"  . C   A 1 47  ? 17.640 27.723  35.136 1.00 52.53 ? 48  C   B "O4'"  1 
ATOM   1111 C "C3'"  . C   A 1 47  ? 19.087 29.544  35.671 1.00 48.24 ? 48  C   B "C3'"  1 
ATOM   1112 O "O3'"  . C   A 1 47  ? 20.515 29.450  35.697 1.00 43.36 ? 48  C   B "O3'"  1 
ATOM   1113 C "C2'"  . C   A 1 47  ? 18.551 29.765  34.252 1.00 47.86 ? 48  C   B "C2'"  1 
ATOM   1114 O "O2'"  . C   A 1 47  ? 19.552 29.879  33.268 1.00 47.99 ? 48  C   B "O2'"  1 
ATOM   1115 C "C1'"  . C   A 1 47  ? 17.703 28.512  33.989 1.00 49.20 ? 48  C   B "C1'"  1 
ATOM   1116 N N1     . C   A 1 47  ? 16.343 28.642  33.472 1.00 50.43 ? 48  C   B N1     1 
ATOM   1117 C C2     . C   A 1 47  ? 16.143 28.538  32.095 1.00 48.60 ? 48  C   B C2     1 
ATOM   1118 O O2     . C   A 1 47  ? 17.124 28.476  31.349 1.00 46.56 ? 48  C   B O2     1 
ATOM   1119 N N3     . C   A 1 47  ? 14.887 28.513  31.614 1.00 50.76 ? 48  C   B N3     1 
ATOM   1120 C C4     . C   A 1 47  ? 13.851 28.610  32.443 1.00 52.02 ? 48  C   B C4     1 
ATOM   1121 N N4     . C   A 1 47  ? 12.629 28.520  31.924 1.00 52.60 ? 48  C   B N4     1 
ATOM   1122 C C5     . C   A 1 47  ? 14.030 28.788  33.849 1.00 50.15 ? 48  C   B C5     1 
ATOM   1123 C C6     . C   A 1 47  ? 15.283 28.798  34.312 1.00 51.93 ? 48  C   B C6     1 
ATOM   1124 H "HO2'" . C   A 1 47  ? 19.103 30.040  32.441 1.00 20.00 ? 48  C   B "HO2'" 1 
ATOM   1125 H H41    . C   A 1 47  ? 11.820 28.597  32.527 1.00 20.00 ? 48  C   B H41    1 
ATOM   1126 H H42    . C   A 1 47  ? 12.512 28.412  30.927 1.00 20.00 ? 48  C   B H42    1 
ATOM   1127 P P      . C   A 1 48  ? 21.444 30.755  35.587 1.00 42.74 ? 49  C   B P      1 
ATOM   1128 O OP1    . C   A 1 48  ? 20.642 31.988  35.809 1.00 40.68 ? 49  C   B OP1    1 
ATOM   1129 O OP2    . C   A 1 48  ? 22.274 30.617  34.367 1.00 40.59 ? 49  C   B OP2    1 
ATOM   1130 O "O5'"  . C   A 1 48  ? 22.451 30.571  36.806 1.00 41.25 ? 49  C   B "O5'"  1 
ATOM   1131 C "C5'"  . C   A 1 48  ? 22.873 29.271  37.213 1.00 42.32 ? 49  C   B "C5'"  1 
ATOM   1132 C "C4'"  . C   A 1 48  ? 23.519 29.344  38.567 1.00 40.64 ? 49  C   B "C4'"  1 
ATOM   1133 O "O4'"  . C   A 1 48  ? 24.779 30.041  38.423 1.00 40.65 ? 49  C   B "O4'"  1 
ATOM   1134 C "C3'"  . C   A 1 48  ? 22.730 30.164  39.572 1.00 39.53 ? 49  C   B "C3'"  1 
ATOM   1135 O "O3'"  . C   A 1 48  ? 21.811 29.343  40.280 1.00 41.40 ? 49  C   B "O3'"  1 
ATOM   1136 C "C2'"  . C   A 1 48  ? 23.821 30.709  40.475 1.00 38.68 ? 49  C   B "C2'"  1 
ATOM   1137 O "O2'"  . C   A 1 48  ? 24.274 29.749  41.408 1.00 37.25 ? 49  C   B "O2'"  1 
ATOM   1138 C "C1'"  . C   A 1 48  ? 24.928 30.991  39.458 1.00 38.02 ? 49  C   B "C1'"  1 
ATOM   1139 N N1     . C   A 1 48  ? 24.848 32.326  38.858 1.00 35.36 ? 49  C   B N1     1 
ATOM   1140 C C2     . C   A 1 48  ? 25.305 33.411  39.582 1.00 32.68 ? 49  C   B C2     1 
ATOM   1141 O O2     . C   A 1 48  ? 25.751 33.226  40.719 1.00 31.45 ? 49  C   B O2     1 
ATOM   1142 N N3     . C   A 1 48  ? 25.255 34.644  39.032 1.00 34.15 ? 49  C   B N3     1 
ATOM   1143 C C4     . C   A 1 48  ? 24.771 34.800  37.799 1.00 33.94 ? 49  C   B C4     1 
ATOM   1144 N N4     . C   A 1 48  ? 24.742 36.028  37.284 1.00 34.75 ? 49  C   B N4     1 
ATOM   1145 C C5     . C   A 1 48  ? 24.291 33.707  37.037 1.00 34.22 ? 49  C   B C5     1 
ATOM   1146 C C6     . C   A 1 48  ? 24.342 32.497  37.600 1.00 33.28 ? 49  C   B C6     1 
ATOM   1147 H "HO2'" . C   A 1 48  ? 24.941 30.187  41.937 1.00 20.00 ? 49  C   B "HO2'" 1 
ATOM   1148 H H41    . C   A 1 48  ? 24.375 36.187  36.360 1.00 20.00 ? 49  C   B H41    1 
ATOM   1149 H H42    . C   A 1 48  ? 25.065 36.820  37.817 1.00 20.00 ? 49  C   B H42    1 
ATOM   1150 P P      . G   A 1 49  ? 20.484 29.999  40.904 1.00 46.13 ? 50  G   B P      1 
ATOM   1151 O OP1    . G   A 1 49  ? 19.715 28.903  41.550 1.00 44.76 ? 50  G   B OP1    1 
ATOM   1152 O OP2    . G   A 1 49  ? 19.847 30.826  39.850 1.00 45.68 ? 50  G   B OP2    1 
ATOM   1153 O "O5'"  . G   A 1 49  ? 21.025 30.989  42.025 1.00 47.55 ? 50  G   B "O5'"  1 
ATOM   1154 C "C5'"  . G   A 1 49  ? 21.564 30.478  43.239 1.00 52.43 ? 50  G   B "C5'"  1 
ATOM   1155 C "C4'"  . G   A 1 49  ? 21.784 31.591  44.228 1.00 53.51 ? 50  G   B "C4'"  1 
ATOM   1156 O "O4'"  . G   A 1 49  ? 22.874 32.438  43.775 1.00 50.71 ? 50  G   B "O4'"  1 
ATOM   1157 C "C3'"  . G   A 1 49  ? 20.618 32.553  44.396 1.00 54.68 ? 50  G   B "C3'"  1 
ATOM   1158 O "O3'"  . G   A 1 49  ? 19.640 32.033  45.290 1.00 59.01 ? 50  G   B "O3'"  1 
ATOM   1159 C "C2'"  . G   A 1 49  ? 21.315 33.787  44.953 1.00 52.55 ? 50  G   B "C2'"  1 
ATOM   1160 O "O2'"  . G   A 1 49  ? 21.605 33.672  46.336 1.00 52.28 ? 50  G   B "O2'"  1 
ATOM   1161 C "C1'"  . G   A 1 49  ? 22.613 33.781  44.147 1.00 51.89 ? 50  G   B "C1'"  1 
ATOM   1162 N N9     . G   A 1 49  ? 22.517 34.568  42.919 1.00 47.97 ? 50  G   B N9     1 
ATOM   1163 C C8     . G   A 1 49  ? 22.309 34.088  41.654 1.00 46.37 ? 50  G   B C8     1 
ATOM   1164 N N7     . G   A 1 49  ? 22.286 35.034  40.748 1.00 45.39 ? 50  G   B N7     1 
ATOM   1165 C C5     . G   A 1 49  ? 22.485 36.203  41.468 1.00 45.89 ? 50  G   B C5     1 
ATOM   1166 C C6     . G   A 1 49  ? 22.556 37.555  41.023 1.00 42.51 ? 50  G   B C6     1 
ATOM   1167 O O6     . G   A 1 49  ? 22.459 37.999  39.868 1.00 43.51 ? 50  G   B O6     1 
ATOM   1168 N N1     . G   A 1 49  ? 22.758 38.427  42.086 1.00 42.40 ? 50  G   B N1     1 
ATOM   1169 C C2     . G   A 1 49  ? 22.880 38.050  43.398 1.00 45.69 ? 50  G   B C2     1 
ATOM   1170 N N2     . G   A 1 49  ? 23.059 39.032  44.274 1.00 46.52 ? 50  G   B N2     1 
ATOM   1171 N N3     . G   A 1 49  ? 22.820 36.799  43.825 1.00 46.90 ? 50  G   B N3     1 
ATOM   1172 C C4     . G   A 1 49  ? 22.625 35.936  42.812 1.00 46.58 ? 50  G   B C4     1 
ATOM   1173 H "HO2'" . G   A 1 49  ? 22.017 34.497  46.593 1.00 20.00 ? 50  G   B "HO2'" 1 
ATOM   1174 H H1     . G   A 1 49  ? 22.836 39.409  41.853 1.00 20.00 ? 50  G   B H1     1 
ATOM   1175 H H21    . G   A 1 49  ? 23.156 38.814  45.254 1.00 20.00 ? 50  G   B H21    1 
ATOM   1176 H H22    . G   A 1 49  ? 23.118 39.991  43.958 1.00 20.00 ? 50  G   B H22    1 
ATOM   1177 P P      . A   A 1 50  ? 18.164 32.679  45.317 1.00 62.26 ? 51  A   B P      1 
ATOM   1178 O OP1    . A   A 1 50  ? 17.376 31.919  46.327 1.00 60.49 ? 51  A   B OP1    1 
ATOM   1179 O OP2    . A   A 1 50  ? 17.663 32.772  43.918 1.00 62.34 ? 51  A   B OP2    1 
ATOM   1180 O "O5'"  . A   A 1 50  ? 18.404 34.168  45.841 1.00 62.73 ? 51  A   B "O5'"  1 
ATOM   1181 C "C5'"  . A   A 1 50  ? 19.002 34.403  47.112 1.00 63.16 ? 51  A   B "C5'"  1 
ATOM   1182 C "C4'"  . A   A 1 50  ? 19.040 35.881  47.409 1.00 62.59 ? 51  A   B "C4'"  1 
ATOM   1183 O "O4'"  . A   A 1 50  ? 20.074 36.540  46.629 1.00 62.19 ? 51  A   B "O4'"  1 
ATOM   1184 C "C3'"  . A   A 1 50  ? 17.774 36.625  47.044 1.00 62.19 ? 51  A   B "C3'"  1 
ATOM   1185 O "O3'"  . A   A 1 50  ? 16.797 36.503  48.051 1.00 62.21 ? 51  A   B "O3'"  1 
ATOM   1186 C "C2'"  . A   A 1 50  ? 18.264 38.056  46.908 1.00 57.74 ? 51  A   B "C2'"  1 
ATOM   1187 O "O2'"  . A   A 1 50  ? 18.394 38.689  48.166 1.00 58.45 ? 51  A   B "O2'"  1 
ATOM   1188 C "C1'"  . A   A 1 50  ? 19.625 37.832  46.240 1.00 59.51 ? 51  A   B "C1'"  1 
ATOM   1189 N N9     . A   A 1 50  ? 19.510 37.852  44.777 1.00 57.88 ? 51  A   B N9     1 
ATOM   1190 C C8     . A   A 1 50  ? 19.287 36.785  43.937 1.00 55.73 ? 51  A   B C8     1 
ATOM   1191 N N7     . A   A 1 50  ? 19.210 37.124  42.671 1.00 53.70 ? 51  A   B N7     1 
ATOM   1192 C C5     . A   A 1 50  ? 19.397 38.500  42.686 1.00 54.73 ? 51  A   B C5     1 
ATOM   1193 C C6     . A   A 1 50  ? 19.419 39.455  41.659 1.00 54.24 ? 51  A   B C6     1 
ATOM   1194 N N6     . A   A 1 50  ? 19.239 39.163  40.372 1.00 54.13 ? 51  A   B N6     1 
ATOM   1195 N N1     . A   A 1 50  ? 19.635 40.742  42.005 1.00 54.11 ? 51  A   B N1     1 
ATOM   1196 C C2     . A   A 1 50  ? 19.811 41.035  43.297 1.00 56.05 ? 51  A   B C2     1 
ATOM   1197 N N3     . A   A 1 50  ? 19.806 40.227  44.353 1.00 54.18 ? 51  A   B N3     1 
ATOM   1198 C C4     . A   A 1 50  ? 19.591 38.960  43.972 1.00 56.23 ? 51  A   B C4     1 
ATOM   1199 H "HO2'" . A   A 1 50  ? 18.697 39.582  48.009 1.00 20.00 ? 51  A   B "HO2'" 1 
ATOM   1200 H H61    . A   A 1 50  ? 19.078 38.206  40.088 1.00 20.00 ? 51  A   B H61    1 
ATOM   1201 H H62    . A   A 1 50  ? 19.284 39.895  39.678 1.00 20.00 ? 51  A   B H62    1 
ATOM   1202 P P      . G   A 1 51  ? 15.312 36.995  47.745 1.00 63.94 ? 52  G   B P      1 
ATOM   1203 O OP1    . G   A 1 51  ? 14.444 36.403  48.794 1.00 64.28 ? 52  G   B OP1    1 
ATOM   1204 O OP2    . G   A 1 51  ? 15.026 36.706  46.313 1.00 62.98 ? 52  G   B OP2    1 
ATOM   1205 O "O5'"  . G   A 1 51  ? 15.408 38.580  47.921 1.00 63.05 ? 52  G   B "O5'"  1 
ATOM   1206 C "C5'"  . G   A 1 51  ? 14.459 39.431  47.296 1.00 63.74 ? 52  G   B "C5'"  1 
ATOM   1207 C "C4'"  . G   A 1 51  ? 15.045 40.800  47.056 1.00 61.35 ? 52  G   B "C4'"  1 
ATOM   1208 O "O4'"  . G   A 1 51  ? 16.344 40.693  46.411 1.00 58.22 ? 52  G   B "O4'"  1 
ATOM   1209 C "C3'"  . G   A 1 51  ? 14.213 41.630  46.093 1.00 63.68 ? 52  G   B "C3'"  1 
ATOM   1210 O "O3'"  . G   A 1 51  ? 13.110 42.250  46.741 1.00 65.68 ? 52  G   B "O3'"  1 
ATOM   1211 C "C2'"  . G   A 1 51  ? 15.242 42.601  45.526 1.00 58.06 ? 52  G   B "C2'"  1 
ATOM   1212 O "O2'"  . G   A 1 51  ? 15.498 43.700  46.378 1.00 57.29 ? 52  G   B "O2'"  1 
ATOM   1213 C "C1'"  . G   A 1 51  ? 16.461 41.690  45.398 1.00 56.20 ? 52  G   B "C1'"  1 
ATOM   1214 N N9     . G   A 1 51  ? 16.450 41.006  44.110 1.00 51.67 ? 52  G   B N9     1 
ATOM   1215 C C8     . G   A 1 51  ? 16.308 39.660  43.891 1.00 48.50 ? 52  G   B C8     1 
ATOM   1216 N N7     . G   A 1 51  ? 16.250 39.348  42.626 1.00 49.85 ? 52  G   B N7     1 
ATOM   1217 C C5     . G   A 1 51  ? 16.382 40.564  41.971 1.00 49.91 ? 52  G   B C5     1 
ATOM   1218 C C6     . G   A 1 51  ? 16.367 40.862  40.585 1.00 48.54 ? 52  G   B C6     1 
ATOM   1219 O O6     . G   A 1 51  ? 16.209 40.094  39.631 1.00 49.05 ? 52  G   B O6     1 
ATOM   1220 N N1     . G   A 1 51  ? 16.540 42.219  40.352 1.00 47.63 ? 52  G   B N1     1 
ATOM   1221 C C2     . G   A 1 51  ? 16.686 43.166  41.330 1.00 48.45 ? 52  G   B C2     1 
ATOM   1222 N N2     . G   A 1 51  ? 16.826 44.432  40.904 1.00 49.28 ? 52  G   B N2     1 
ATOM   1223 N N3     . G   A 1 51  ? 16.691 42.903  42.628 1.00 48.46 ? 52  G   B N3     1 
ATOM   1224 C C4     . G   A 1 51  ? 16.528 41.592  42.873 1.00 49.69 ? 52  G   B C4     1 
ATOM   1225 H "HO2'" . G   A 1 51  ? 16.139 44.256  45.939 1.00 20.00 ? 52  G   B "HO2'" 1 
ATOM   1226 H H1     . G   A 1 51  ? 16.533 42.531  39.393 1.00 20.00 ? 52  G   B H1     1 
ATOM   1227 H H21    . G   A 1 51  ? 16.920 45.181  41.574 1.00 20.00 ? 52  G   B H21    1 
ATOM   1228 H H22    . G   A 1 51  ? 16.803 44.653  39.916 1.00 20.00 ? 52  G   B H22    1 
ATOM   1229 P P      . G   A 1 52  ? 11.626 42.021  46.162 1.00 65.56 ? 53  G   B P      1 
ATOM   1230 O OP1    . G   A 1 52  ? 10.654 42.564  47.152 1.00 65.63 ? 53  G   B OP1    1 
ATOM   1231 O OP2    . G   A 1 52  ? 11.520 40.599  45.731 1.00 66.49 ? 53  G   B OP2    1 
ATOM   1232 O "O5'"  . G   A 1 52  ? 11.590 42.968  44.891 1.00 67.33 ? 53  G   B "O5'"  1 
ATOM   1233 C "C5'"  . G   A 1 52  ? 11.869 44.340  45.058 1.00 67.43 ? 53  G   B "C5'"  1 
ATOM   1234 C "C4'"  . G   A 1 52  ? 12.156 44.984  43.743 1.00 66.30 ? 53  G   B "C4'"  1 
ATOM   1235 O "O4'"  . G   A 1 52  ? 13.247 44.283  43.095 1.00 63.02 ? 53  G   B "O4'"  1 
ATOM   1236 C "C3'"  . G   A 1 52  ? 11.070 44.894  42.690 1.00 63.46 ? 53  G   B "C3'"  1 
ATOM   1237 O "O3'"  . G   A 1 52  ? 9.995  45.788  42.930 1.00 66.21 ? 53  G   B "O3'"  1 
ATOM   1238 C "C2'"  . G   A 1 52  ? 11.858 45.267  41.445 1.00 60.80 ? 53  G   B "C2'"  1 
ATOM   1239 O "O2'"  . G   A 1 52  ? 12.109 46.663  41.372 1.00 57.42 ? 53  G   B "O2'"  1 
ATOM   1240 C "C1'"  . G   A 1 52  ? 13.165 44.503  41.696 1.00 59.06 ? 53  G   B "C1'"  1 
ATOM   1241 N N9     . G   A 1 52  ? 13.218 43.221  40.998 1.00 52.62 ? 53  G   B N9     1 
ATOM   1242 C C8     . G   A 1 52  ? 13.214 41.958  41.536 1.00 50.56 ? 53  G   B C8     1 
ATOM   1243 N N7     . G   A 1 52  ? 13.301 41.019  40.629 1.00 49.21 ? 53  G   B N7     1 
ATOM   1244 C C5     . G   A 1 52  ? 13.361 41.709  39.429 1.00 50.26 ? 53  G   B C5     1 
ATOM   1245 C C6     . G   A 1 52  ? 13.467 41.237  38.092 1.00 49.87 ? 53  G   B C6     1 
ATOM   1246 O O6     . G   A 1 52  ? 13.554 40.072  37.695 1.00 49.28 ? 53  G   B O6     1 
ATOM   1247 N N1     . G   A 1 52  ? 13.468 42.284  37.175 1.00 49.21 ? 53  G   B N1     1 
ATOM   1248 C C2     . G   A 1 52  ? 13.396 43.615  37.501 1.00 50.83 ? 53  G   B C2     1 
ATOM   1249 N N2     . G   A 1 52  ? 13.412 44.491  36.486 1.00 51.14 ? 53  G   B N2     1 
ATOM   1250 N N3     . G   A 1 52  ? 13.313 44.062  38.737 1.00 50.66 ? 53  G   B N3     1 
ATOM   1251 C C4     . G   A 1 52  ? 13.299 43.068  39.640 1.00 50.74 ? 53  G   B C4     1 
ATOM   1252 H "HO2'" . G   A 1 52  ? 12.598 46.808  40.563 1.00 20.00 ? 53  G   B "HO2'" 1 
ATOM   1253 H H1     . G   A 1 52  ? 13.500 42.050  36.191 1.00 20.00 ? 53  G   B H1     1 
ATOM   1254 H H21    . G   A 1 52  ? 13.376 45.484  36.673 1.00 20.00 ? 53  G   B H21    1 
ATOM   1255 H H22    . G   A 1 52  ? 13.479 44.172  35.527 1.00 20.00 ? 53  G   B H22    1 
ATOM   1256 P P      . U   A 1 53  ? 8.547  45.458  42.313 1.00 67.40 ? 54  U   B P      1 
ATOM   1257 O OP1    . U   A 1 53  ? 7.573  46.417  42.881 1.00 67.16 ? 54  U   B OP1    1 
ATOM   1258 O OP2    . U   A 1 53  ? 8.310  43.993  42.458 1.00 67.15 ? 54  U   B OP2    1 
ATOM   1259 O "O5'"  . U   A 1 53  ? 8.713  45.810  40.771 1.00 68.98 ? 54  U   B "O5'"  1 
ATOM   1260 C "C5'"  . U   A 1 53  ? 8.980  47.151  40.370 1.00 70.37 ? 54  U   B "C5'"  1 
ATOM   1261 C "C4'"  . U   A 1 53  ? 9.057  47.241  38.868 1.00 68.33 ? 54  U   B "C4'"  1 
ATOM   1262 O "O4'"  . U   A 1 53  ? 10.239 46.535  38.401 1.00 67.18 ? 54  U   B "O4'"  1 
ATOM   1263 C "C3'"  . U   A 1 53  ? 7.911  46.570  38.135 1.00 69.02 ? 54  U   B "C3'"  1 
ATOM   1264 O "O3'"  . U   A 1 53  ? 6.791  47.426  38.039 1.00 70.19 ? 54  U   B "O3'"  1 
ATOM   1265 C "C2'"  . U   A 1 53  ? 8.532  46.280  36.782 1.00 65.73 ? 54  U   B "C2'"  1 
ATOM   1266 O "O2'"  . U   A 1 53  ? 8.593  47.434  35.969 1.00 62.95 ? 54  U   B "O2'"  1 
ATOM   1267 C "C1'"  . U   A 1 53  ? 9.934  45.841  37.203 1.00 65.47 ? 54  U   B "C1'"  1 
ATOM   1268 N N1     . U   A 1 53  ? 9.968  44.402  37.484 1.00 63.13 ? 54  U   B N1     1 
ATOM   1269 C C2     . U   A 1 53  ? 10.214 43.566  36.435 1.00 61.55 ? 54  U   B C2     1 
ATOM   1270 O O2     . U   A 1 53  ? 10.457 43.969  35.306 1.00 61.93 ? 54  U   B O2     1 
ATOM   1271 N N3     . U   A 1 53  ? 10.170 42.230  36.737 1.00 60.91 ? 54  U   B N3     1 
ATOM   1272 C C4     . U   A 1 53  ? 9.923  41.659  37.961 1.00 57.89 ? 54  U   B C4     1 
ATOM   1273 O O4     . U   A 1 53  ? 9.819  40.424  38.040 1.00 58.31 ? 54  U   B O4     1 
ATOM   1274 C C5     . U   A 1 53  ? 9.708  42.590  39.015 1.00 60.84 ? 54  U   B C5     1 
ATOM   1275 C C6     . U   A 1 53  ? 9.737  43.901  38.748 1.00 61.70 ? 54  U   B C6     1 
ATOM   1276 H "HO2'" . U   A 1 53  ? 8.974  47.162  35.135 1.00 20.00 ? 54  U   B "HO2'" 1 
ATOM   1277 H H3     . U   A 1 53  ? 10.327 41.604  35.981 1.00 20.00 ? 54  U   B H3     1 
ATOM   1278 P P      . U   A 1 54  ? 5.333  46.824  38.290 1.00 69.78 ? 55  U   B P      1 
ATOM   1279 O OP1    . U   A 1 54  ? 4.328  47.919  38.169 1.00 69.17 ? 55  U   B OP1    1 
ATOM   1280 O OP2    . U   A 1 54  ? 5.410  46.020  39.544 1.00 68.23 ? 55  U   B OP2    1 
ATOM   1281 O "O5'"  . U   A 1 54  ? 5.155  45.812  37.074 1.00 71.04 ? 55  U   B "O5'"  1 
ATOM   1282 C "C5'"  . U   A 1 54  ? 5.182  46.280  35.735 1.00 69.92 ? 55  U   B "C5'"  1 
ATOM   1283 C "C4'"  . U   A 1 54  ? 4.995  45.123  34.794 1.00 67.53 ? 55  U   B "C4'"  1 
ATOM   1284 O "O4'"  . U   A 1 54  ? 6.171  44.273  34.832 1.00 65.61 ? 55  U   B "O4'"  1 
ATOM   1285 C "C3'"  . U   A 1 54  ? 3.844  44.194  35.147 1.00 65.54 ? 55  U   B "C3'"  1 
ATOM   1286 O "O3'"  . U   A 1 54  ? 2.608  44.720  34.653 1.00 60.66 ? 55  U   B "O3'"  1 
ATOM   1287 C "C2'"  . U   A 1 54  ? 4.263  42.907  34.443 1.00 60.86 ? 55  U   B "C2'"  1 
ATOM   1288 O "O2'"  . U   A 1 54  ? 3.988  42.961  33.058 1.00 58.13 ? 55  U   B "O2'"  1 
ATOM   1289 C "C1'"  . U   A 1 54  ? 5.786  42.915  34.665 1.00 62.39 ? 55  U   B "C1'"  1 
ATOM   1290 N N1     . U   A 1 54  ? 6.209  42.177  35.864 1.00 59.24 ? 55  U   B N1     1 
ATOM   1291 C C2     . U   A 1 54  ? 6.564  40.832  35.734 1.00 58.48 ? 55  U   B C2     1 
ATOM   1292 O O2     . U   A 1 54  ? 6.614  40.248  34.658 1.00 57.80 ? 55  U   B O2     1 
ATOM   1293 N N3     . U   A 1 54  ? 6.863  40.201  36.918 1.00 55.31 ? 55  U   B N3     1 
ATOM   1294 C C4     . U   A 1 54  ? 6.858  40.758  38.184 1.00 55.49 ? 55  U   B C4     1 
ATOM   1295 O O4     . U   A 1 54  ? 7.031  40.026  39.164 1.00 55.60 ? 55  U   B O4     1 
ATOM   1296 C C5     . U   A 1 54  ? 6.524  42.150  38.227 1.00 54.82 ? 55  U   B C5     1 
ATOM   1297 C C6     . U   A 1 54  ? 6.219  42.794  37.098 1.00 56.67 ? 55  U   B C6     1 
ATOM   1298 H "HO2'" . U   A 1 54  ? 4.277  42.134  32.681 1.00 20.00 ? 55  U   B "HO2'" 1 
ATOM   1299 H H3     . U   A 1 54  ? 7.080  39.215  36.874 1.00 20.00 ? 55  U   B H3     1 
ATOM   1300 P P      . C   A 1 55  ? 1.268  44.604  35.541 1.00 58.35 ? 56  C   B P      1 
ATOM   1301 O OP1    . C   A 1 55  ? 0.117  44.903  34.652 1.00 59.02 ? 56  C   B OP1    1 
ATOM   1302 O OP2    . C   A 1 55  ? 1.468  45.402  36.782 1.00 57.95 ? 56  C   B OP2    1 
ATOM   1303 O "O5'"  . C   A 1 55  ? 1.204  43.061  35.924 1.00 56.07 ? 56  C   B "O5'"  1 
ATOM   1304 C "C5'"  . C   A 1 55  ? 0.081  42.521  36.598 1.00 50.09 ? 56  C   B "C5'"  1 
ATOM   1305 C "C4'"  . C   A 1 55  ? -0.237 41.159  36.043 1.00 46.64 ? 56  C   B "C4'"  1 
ATOM   1306 O "O4'"  . C   A 1 55  ? -0.803 41.332  34.721 1.00 44.65 ? 56  C   B "O4'"  1 
ATOM   1307 C "C3'"  . C   A 1 55  ? 0.958  40.264  35.784 1.00 47.05 ? 56  C   B "C3'"  1 
ATOM   1308 O "O3'"  . C   A 1 55  ? 1.370  39.583  36.949 1.00 49.14 ? 56  C   B "O3'"  1 
ATOM   1309 C "C2'"  . C   A 1 55  ? 0.417  39.288  34.757 1.00 42.65 ? 56  C   B "C2'"  1 
ATOM   1310 O "O2'"  . C   A 1 55  ? -0.334 38.261  35.368 1.00 38.09 ? 56  C   B "O2'"  1 
ATOM   1311 C "C1'"  . C   A 1 55  ? -0.482 40.202  33.927 1.00 41.52 ? 56  C   B "C1'"  1 
ATOM   1312 N N1     . C   A 1 55  ? 0.164  40.668  32.698 1.00 39.28 ? 56  C   B N1     1 
ATOM   1313 C C2     . C   A 1 55  ? 0.549  39.718  31.765 1.00 36.32 ? 56  C   B C2     1 
ATOM   1314 O O2     . C   A 1 55  ? 0.370  38.524  32.035 1.00 35.99 ? 56  C   B O2     1 
ATOM   1315 N N3     . C   A 1 55  ? 1.106  40.118  30.595 1.00 36.22 ? 56  C   B N3     1 
ATOM   1316 C C4     . C   A 1 55  ? 1.285  41.421  30.351 1.00 40.08 ? 56  C   B C4     1 
ATOM   1317 N N4     . C   A 1 55  ? 1.803  41.769  29.172 1.00 36.90 ? 56  C   B N4     1 
ATOM   1318 C C5     . C   A 1 55  ? 0.924  42.417  31.307 1.00 37.14 ? 56  C   B C5     1 
ATOM   1319 C C6     . C   A 1 55  ? 0.372  42.000  32.456 1.00 40.00 ? 56  C   B C6     1 
ATOM   1320 H "HO2'" . C   A 1 55  ? -0.652 37.696  34.665 1.00 20.00 ? 56  C   B "HO2'" 1 
ATOM   1321 H H41    . C   A 1 55  ? 1.965  42.741  28.961 1.00 20.00 ? 56  C   B H41    1 
ATOM   1322 H H42    . C   A 1 55  ? 2.068  41.059  28.505 1.00 20.00 ? 56  C   B H42    1 
ATOM   1323 P P      . G   A 1 56  ? 2.936  39.421  37.242 1.00 51.62 ? 57  G   B P      1 
ATOM   1324 O OP1    . G   A 1 56  ? 3.124  38.771  38.578 1.00 50.37 ? 57  G   B OP1    1 
ATOM   1325 O OP2    . G   A 1 56  ? 3.543  40.759  36.974 1.00 50.00 ? 57  G   B OP2    1 
ATOM   1326 O "O5'"  . G   A 1 56  ? 3.421  38.402  36.115 1.00 54.17 ? 57  G   B "O5'"  1 
ATOM   1327 C "C5'"  . G   A 1 56  ? 3.023  37.032  36.161 1.00 56.76 ? 57  G   B "C5'"  1 
ATOM   1328 C "C4'"  . G   A 1 56  ? 3.466  36.299  34.910 1.00 55.61 ? 57  G   B "C4'"  1 
ATOM   1329 O "O4'"  . G   A 1 56  ? 2.774  36.835  33.751 1.00 55.39 ? 57  G   B "O4'"  1 
ATOM   1330 C "C3'"  . G   A 1 56  ? 4.944  36.406  34.571 1.00 53.83 ? 57  G   B "C3'"  1 
ATOM   1331 O "O3'"  . G   A 1 56  ? 5.664  35.396  35.261 1.00 53.82 ? 57  G   B "O3'"  1 
ATOM   1332 C "C2'"  . G   A 1 56  ? 4.956  36.179  33.063 1.00 52.99 ? 57  G   B "C2'"  1 
ATOM   1333 O "O2'"  . G   A 1 56  ? 4.893  34.814  32.716 1.00 51.29 ? 57  G   B "O2'"  1 
ATOM   1334 C "C1'"  . G   A 1 56  ? 3.657  36.855  32.643 1.00 52.40 ? 57  G   B "C1'"  1 
ATOM   1335 N N9     . G   A 1 56  ? 3.854  38.249  32.268 1.00 47.81 ? 57  G   B N9     1 
ATOM   1336 C C8     . G   A 1 56  ? 3.626  39.355  33.035 1.00 46.25 ? 57  G   B C8     1 
ATOM   1337 N N7     . G   A 1 56  ? 3.896  40.468  32.412 1.00 45.38 ? 57  G   B N7     1 
ATOM   1338 C C5     . G   A 1 56  ? 4.328  40.062  31.162 1.00 45.67 ? 57  G   B C5     1 
ATOM   1339 C C6     . G   A 1 56  ? 4.755  40.821  30.047 1.00 45.63 ? 57  G   B C6     1 
ATOM   1340 O O6     . G   A 1 56  ? 4.835  42.048  29.929 1.00 46.88 ? 57  G   B O6     1 
ATOM   1341 N N1     . G   A 1 56  ? 5.104  40.009  28.982 1.00 43.47 ? 57  G   B N1     1 
ATOM   1342 C C2     . G   A 1 56  ? 5.040  38.642  28.995 1.00 45.86 ? 57  G   B C2     1 
ATOM   1343 N N2     . G   A 1 56  ? 5.404  38.020  27.873 1.00 47.15 ? 57  G   B N2     1 
ATOM   1344 N N3     . G   A 1 56  ? 4.644  37.925  30.022 1.00 47.58 ? 57  G   B N3     1 
ATOM   1345 C C4     . G   A 1 56  ? 4.310  38.693  31.061 1.00 46.95 ? 57  G   B C4     1 
ATOM   1346 H "HO2'" . G   A 1 56  ? 4.902  34.749  31.764 1.00 20.00 ? 57  G   B "HO2'" 1 
ATOM   1347 H H1     . G   A 1 56  ? 5.450  40.461  28.151 1.00 20.00 ? 57  G   B H1     1 
ATOM   1348 H H21    . G   A 1 56  ? 5.422  37.013  27.847 1.00 20.00 ? 57  G   B H21    1 
ATOM   1349 H H22    . G   A 1 56  ? 5.748  38.548  27.087 1.00 20.00 ? 57  G   B H22    1 
ATOM   1350 P P      . A   A 1 57  ? 7.124  35.717  35.832 1.00 52.18 ? 58  A   B P      1 
ATOM   1351 O OP1    . A   A 1 57  ? 7.571  34.569  36.658 1.00 48.84 ? 58  A   B OP1    1 
ATOM   1352 O OP2    . A   A 1 57  ? 7.055  37.075  36.442 1.00 50.69 ? 58  A   B OP2    1 
ATOM   1353 O "O5'"  . A   A 1 57  ? 8.016  35.838  34.510 1.00 52.18 ? 58  A   B "O5'"  1 
ATOM   1354 C "C5'"  . A   A 1 57  ? 8.650  34.701  33.904 1.00 50.65 ? 58  A   B "C5'"  1 
ATOM   1355 C "C4'"  . A   A 1 57  ? 10.109 35.002  33.680 1.00 47.65 ? 58  A   B "C4'"  1 
ATOM   1356 O "O4'"  . A   A 1 57  ? 10.186 36.308  33.076 1.00 44.21 ? 58  A   B "O4'"  1 
ATOM   1357 C "C3'"  . A   A 1 57  ? 10.873 35.086  34.998 1.00 48.08 ? 58  A   B "C3'"  1 
ATOM   1358 O "O3'"  . A   A 1 57  ? 11.730 33.956  35.232 1.00 50.55 ? 58  A   B "O3'"  1 
ATOM   1359 C "C2'"  . A   A 1 57  ? 11.792 36.296  34.861 1.00 44.43 ? 58  A   B "C2'"  1 
ATOM   1360 O "O2'"  . A   A 1 57  ? 13.147 35.946  34.778 1.00 41.58 ? 58  A   B "O2'"  1 
ATOM   1361 C "C1'"  . A   A 1 57  ? 11.317 36.971  33.571 1.00 43.38 ? 58  A   B "C1'"  1 
ATOM   1362 N N9     . A   A 1 57  ? 11.041 38.398  33.653 1.00 40.70 ? 58  A   B N9     1 
ATOM   1363 C C8     . A   A 1 57  ? 10.516 39.121  34.684 1.00 39.60 ? 58  A   B C8     1 
ATOM   1364 N N7     . A   A 1 57  ? 10.444 40.406  34.437 1.00 37.78 ? 58  A   B N7     1 
ATOM   1365 C C5     . A   A 1 57  ? 10.950 40.530  33.152 1.00 36.68 ? 58  A   B C5     1 
ATOM   1366 C C6     . A   A 1 57  ? 11.152 41.647  32.320 1.00 37.02 ? 58  A   B C6     1 
ATOM   1367 N N6     . A   A 1 57  ? 10.837 42.895  32.668 1.00 36.57 ? 58  A   B N6     1 
ATOM   1368 N N1     . A   A 1 57  ? 11.685 41.426  31.097 1.00 39.85 ? 58  A   B N1     1 
ATOM   1369 C C2     . A   A 1 57  ? 11.987 40.172  30.748 1.00 42.83 ? 58  A   B C2     1 
ATOM   1370 N N3     . A   A 1 57  ? 11.839 39.049  31.446 1.00 42.12 ? 58  A   B N3     1 
ATOM   1371 C C4     . A   A 1 57  ? 11.314 39.302  32.654 1.00 39.24 ? 58  A   B C4     1 
ATOM   1372 H "HO2'" . A   A 1 57  ? 13.611 36.784  34.737 1.00 20.00 ? 58  A   B "HO2'" 1 
ATOM   1373 H H61    . A   A 1 57  ? 10.420 43.082  33.567 1.00 20.00 ? 58  A   B H61    1 
ATOM   1374 H H62    . A   A 1 57  ? 10.982 43.656  32.017 1.00 20.00 ? 58  A   B H62    1 
ATOM   1375 P P      . A   A 1 58  ? 11.529 32.560  34.430 1.00 52.37 ? 59  A   B P      1 
ATOM   1376 O OP1    . A   A 1 58  ? 10.676 32.702  33.229 1.00 52.59 ? 59  A   B OP1    1 
ATOM   1377 O OP2    . A   A 1 58  ? 11.181 31.514  35.434 1.00 51.08 ? 59  A   B OP2    1 
ATOM   1378 O "O5'"  . A   A 1 58  ? 12.996 32.232  33.889 1.00 51.70 ? 59  A   B "O5'"  1 
ATOM   1379 C "C5'"  . A   A 1 58  ? 14.105 32.070  34.778 1.00 49.50 ? 59  A   B "C5'"  1 
ATOM   1380 C "C4'"  . A   A 1 58  ? 15.400 32.375  34.062 1.00 45.50 ? 59  A   B "C4'"  1 
ATOM   1381 O "O4'"  . A   A 1 58  ? 15.616 31.383  33.028 1.00 44.51 ? 59  A   B "O4'"  1 
ATOM   1382 C "C3'"  . A   A 1 58  ? 15.438 33.720  33.348 1.00 43.12 ? 59  A   B "C3'"  1 
ATOM   1383 O "O3'"  . A   A 1 58  ? 15.944 34.729  34.207 1.00 36.16 ? 59  A   B "O3'"  1 
ATOM   1384 C "C2'"  . A   A 1 58  ? 16.413 33.474  32.212 1.00 43.54 ? 59  A   B "C2'"  1 
ATOM   1385 O "O2'"  . A   A 1 58  ? 17.743 33.595  32.668 1.00 44.30 ? 59  A   B "O2'"  1 
ATOM   1386 C "C1'"  . A   A 1 58  ? 16.121 32.012  31.866 1.00 44.17 ? 59  A   B "C1'"  1 
ATOM   1387 N N9     . A   A 1 58  ? 15.118 31.869  30.821 1.00 42.30 ? 59  A   B N9     1 
ATOM   1388 C C8     . A   A 1 58  ? 13.825 31.470  30.990 1.00 40.54 ? 59  A   B C8     1 
ATOM   1389 N N7     . A   A 1 58  ? 13.147 31.396  29.873 1.00 40.46 ? 59  A   B N7     1 
ATOM   1390 C C5     . A   A 1 58  ? 14.060 31.778  28.908 1.00 41.14 ? 59  A   B C5     1 
ATOM   1391 C C6     . A   A 1 58  ? 13.961 31.899  27.524 1.00 39.61 ? 59  A   B C6     1 
ATOM   1392 N N6     . A   A 1 58  ? 12.844 31.624  26.852 1.00 37.87 ? 59  A   B N6     1 
ATOM   1393 N N1     . A   A 1 58  ? 15.049 32.314  26.843 1.00 39.59 ? 59  A   B N1     1 
ATOM   1394 C C2     . A   A 1 58  ? 16.158 32.579  27.533 1.00 41.17 ? 59  A   B C2     1 
ATOM   1395 N N3     . A   A 1 58  ? 16.382 32.498  28.840 1.00 41.79 ? 59  A   B N3     1 
ATOM   1396 C C4     . A   A 1 58  ? 15.280 32.083  29.478 1.00 41.84 ? 59  A   B C4     1 
ATOM   1397 H "HO2'" . A   A 1 58  ? 18.331 33.425  31.935 1.00 20.00 ? 59  A   B "HO2'" 1 
ATOM   1398 H H61    . A   A 1 58  ? 12.031 31.287  27.352 1.00 20.00 ? 59  A   B H61    1 
ATOM   1399 H H62    . A   A 1 58  ? 12.808 31.724  25.844 1.00 20.00 ? 59  A   B H62    1 
ATOM   1400 P P      . U   A 1 59  ? 15.914 36.254  33.730 1.00 33.25 ? 60  U   B P      1 
ATOM   1401 O OP1    . U   A 1 59  ? 16.203 37.136  34.884 1.00 33.52 ? 60  U   B OP1    1 
ATOM   1402 O OP2    . U   A 1 59  ? 14.688 36.467  32.951 1.00 33.48 ? 60  U   B OP2    1 
ATOM   1403 O "O5'"  . U   A 1 59  ? 17.095 36.384  32.688 1.00 39.12 ? 60  U   B "O5'"  1 
ATOM   1404 C "C5'"  . U   A 1 59  ? 17.163 37.521  31.840 1.00 41.56 ? 60  U   B "C5'"  1 
ATOM   1405 C "C4'"  . U   A 1 59  ? 16.779 37.143  30.431 1.00 43.06 ? 60  U   B "C4'"  1 
ATOM   1406 O "O4'"  . U   A 1 59  ? 15.834 36.056  30.445 1.00 43.05 ? 60  U   B "O4'"  1 
ATOM   1407 C "C3'"  . U   A 1 59  ? 16.120 38.271  29.653 1.00 43.72 ? 60  U   B "C3'"  1 
ATOM   1408 O "O3'"  . U   A 1 59  ? 17.098 38.875  28.807 1.00 44.23 ? 60  U   B "O3'"  1 
ATOM   1409 C "C2'"  . U   A 1 59  ? 15.062 37.578  28.771 1.00 43.36 ? 60  U   B "C2'"  1 
ATOM   1410 O "O2'"  . U   A 1 59  ? 15.326 37.579  27.385 1.00 44.46 ? 60  U   B "O2'"  1 
ATOM   1411 C "C1'"  . U   A 1 59  ? 15.074 36.127  29.265 1.00 41.96 ? 60  U   B "C1'"  1 
ATOM   1412 N N1     . U   A 1 59  ? 13.789 35.434  29.440 1.00 39.34 ? 60  U   B N1     1 
ATOM   1413 C C2     . U   A 1 59  ? 13.038 35.204  28.310 1.00 38.51 ? 60  U   B C2     1 
ATOM   1414 O O2     . U   A 1 59  ? 13.379 35.585  27.207 1.00 37.75 ? 60  U   B O2     1 
ATOM   1415 N N3     . U   A 1 59  ? 11.874 34.508  28.519 1.00 37.99 ? 60  U   B N3     1 
ATOM   1416 C C4     . U   A 1 59  ? 11.397 34.038  29.723 1.00 37.85 ? 60  U   B C4     1 
ATOM   1417 O O4     . U   A 1 59  ? 10.395 33.332  29.745 1.00 40.54 ? 60  U   B O4     1 
ATOM   1418 C C5     . U   A 1 59  ? 12.218 34.342  30.842 1.00 38.49 ? 60  U   B C5     1 
ATOM   1419 C C6     . U   A 1 59  ? 13.359 35.011  30.667 1.00 38.96 ? 60  U   B C6     1 
ATOM   1420 H "HO2'" . U   A 1 59  ? 14.578 37.145  26.974 1.00 20.00 ? 60  U   B "HO2'" 1 
ATOM   1421 H H3     . U   A 1 59  ? 11.307 34.327  27.698 1.00 20.00 ? 60  U   B H3     1 
ATOM   1422 P P      . C   A 1 60  ? 18.017 40.084  29.337 1.00 45.03 ? 61  C   B P      1 
ATOM   1423 O OP1    . C   A 1 60  ? 18.741 40.607  28.153 1.00 45.75 ? 61  C   B OP1    1 
ATOM   1424 O OP2    . C   A 1 60  ? 18.783 39.635  30.527 1.00 45.92 ? 61  C   B OP2    1 
ATOM   1425 O "O5'"  . C   A 1 60  ? 16.990 41.204  29.789 1.00 45.14 ? 61  C   B "O5'"  1 
ATOM   1426 C "C5'"  . C   A 1 60  ? 16.675 42.282  28.922 1.00 45.91 ? 61  C   B "C5'"  1 
ATOM   1427 C "C4'"  . C   A 1 60  ? 16.076 43.404  29.717 1.00 43.66 ? 61  C   B "C4'"  1 
ATOM   1428 O "O4'"  . C   A 1 60  ? 14.789 42.964  30.232 1.00 43.88 ? 61  C   B "O4'"  1 
ATOM   1429 C "C3'"  . C   A 1 60  ? 16.882 43.763  30.956 1.00 46.68 ? 61  C   B "C3'"  1 
ATOM   1430 O "O3'"  . C   A 1 60  ? 17.913 44.702  30.667 1.00 51.28 ? 61  C   B "O3'"  1 
ATOM   1431 C "C2'"  . C   A 1 60  ? 15.821 44.326  31.886 1.00 44.23 ? 61  C   B "C2'"  1 
ATOM   1432 O "O2'"  . C   A 1 60  ? 15.509 45.671  31.594 1.00 44.24 ? 61  C   B "O2'"  1 
ATOM   1433 C "C1'"  . C   A 1 60  ? 14.634 43.413  31.566 1.00 43.16 ? 61  C   B "C1'"  1 
ATOM   1434 N N1     . C   A 1 60  ? 14.541 42.235  32.439 1.00 37.19 ? 61  C   B N1     1 
ATOM   1435 C C2     . C   A 1 60  ? 14.201 42.425  33.778 1.00 33.61 ? 61  C   B C2     1 
ATOM   1436 O O2     . C   A 1 60  ? 14.018 43.581  34.189 1.00 32.32 ? 61  C   B O2     1 
ATOM   1437 N N3     . C   A 1 60  ? 14.084 41.356  34.595 1.00 37.64 ? 61  C   B N3     1 
ATOM   1438 C C4     . C   A 1 60  ? 14.300 40.132  34.115 1.00 37.15 ? 61  C   B C4     1 
ATOM   1439 N N4     . C   A 1 60  ? 14.162 39.108  34.955 1.00 37.84 ? 61  C   B N4     1 
ATOM   1440 C C5     . C   A 1 60  ? 14.660 39.904  32.754 1.00 35.84 ? 61  C   B C5     1 
ATOM   1441 C C6     . C   A 1 60  ? 14.769 40.975  31.956 1.00 35.53 ? 61  C   B C6     1 
ATOM   1442 H "HO2'" . C   A 1 60  ? 14.839 45.935  32.226 1.00 20.00 ? 61  C   B "HO2'" 1 
ATOM   1443 H H41    . C   A 1 60  ? 14.310 38.165  34.632 1.00 20.00 ? 61  C   B H41    1 
ATOM   1444 H H42    . C   A 1 60  ? 13.889 39.265  35.913 1.00 20.00 ? 61  C   B H42    1 
ATOM   1445 P P      . C   A 1 61  ? 19.236 44.733  31.590 1.00 56.50 ? 62  C   B P      1 
ATOM   1446 O OP1    . C   A 1 61  ? 20.452 44.620  30.740 1.00 57.12 ? 62  C   B OP1    1 
ATOM   1447 O OP2    . C   A 1 61  ? 19.022 43.764  32.702 1.00 56.65 ? 62  C   B OP2    1 
ATOM   1448 O "O5'"  . C   A 1 61  ? 19.209 46.177  32.254 1.00 57.53 ? 62  C   B "O5'"  1 
ATOM   1449 C "C5'"  . C   A 1 61  ? 17.976 46.857  32.452 1.00 58.52 ? 62  C   B "C5'"  1 
ATOM   1450 C "C4'"  . C   A 1 61  ? 17.789 47.203  33.912 1.00 59.68 ? 62  C   B "C4'"  1 
ATOM   1451 O "O4'"  . C   A 1 61  ? 16.759 46.364  34.477 1.00 57.87 ? 62  C   B "O4'"  1 
ATOM   1452 C "C3'"  . C   A 1 61  ? 18.993 46.988  34.814 1.00 60.87 ? 62  C   B "C3'"  1 
ATOM   1453 O "O3'"  . C   A 1 61  ? 19.830 48.143  34.746 1.00 62.69 ? 62  C   B "O3'"  1 
ATOM   1454 C "C2'"  . C   A 1 61  ? 18.350 46.828  36.187 1.00 57.68 ? 62  C   B "C2'"  1 
ATOM   1455 O "O2'"  . C   A 1 61  ? 18.042 48.057  36.814 1.00 58.53 ? 62  C   B "O2'"  1 
ATOM   1456 C "C1'"  . C   A 1 61  ? 17.042 46.115  35.835 1.00 58.03 ? 62  C   B "C1'"  1 
ATOM   1457 N N1     . C   A 1 61  ? 17.061 44.664  36.031 1.00 56.95 ? 62  C   B N1     1 
ATOM   1458 C C2     . C   A 1 61  ? 16.832 44.161  37.311 1.00 56.68 ? 62  C   B C2     1 
ATOM   1459 O O2     . C   A 1 61  ? 16.696 44.955  38.249 1.00 55.20 ? 62  C   B O2     1 
ATOM   1460 N N3     . C   A 1 61  ? 16.775 42.822  37.492 1.00 55.40 ? 62  C   B N3     1 
ATOM   1461 C C4     . C   A 1 61  ? 16.948 42.000  36.457 1.00 53.73 ? 62  C   B C4     1 
ATOM   1462 N N4     . C   A 1 61  ? 16.844 40.686  36.676 1.00 54.71 ? 62  C   B N4     1 
ATOM   1463 C C5     . C   A 1 61  ? 17.227 42.487  35.145 1.00 55.30 ? 62  C   B C5     1 
ATOM   1464 C C6     . C   A 1 61  ? 17.270 43.814  34.982 1.00 57.41 ? 62  C   B C6     1 
ATOM   1465 H "HO2'" . C   A 1 61  ? 17.627 47.853  37.652 1.00 20.00 ? 62  C   B "HO2'" 1 
ATOM   1466 H H41    . C   A 1 61  ? 16.955 40.034  35.911 1.00 20.00 ? 62  C   B H41    1 
ATOM   1467 H H42    . C   A 1 61  ? 16.619 40.345  37.599 1.00 20.00 ? 62  C   B H42    1 
ATOM   1468 P P      . U   A 1 62  ? 21.307 48.103  35.384 1.00 66.47 ? 63  U   B P      1 
ATOM   1469 O OP1    . U   A 1 62  ? 21.741 49.489  35.729 1.00 67.33 ? 63  U   B OP1    1 
ATOM   1470 O OP2    . U   A 1 62  ? 22.161 47.269  34.493 1.00 66.54 ? 63  U   B OP2    1 
ATOM   1471 O "O5'"  . U   A 1 62  ? 21.075 47.322  36.748 1.00 65.70 ? 63  U   B "O5'"  1 
ATOM   1472 C "C5'"  . U   A 1 62  ? 22.056 47.339  37.750 1.00 65.31 ? 63  U   B "C5'"  1 
ATOM   1473 C "C4'"  . U   A 1 62  ? 21.434 47.671  39.075 1.00 62.51 ? 63  U   B "C4'"  1 
ATOM   1474 O "O4'"  . U   A 1 62  ? 20.126 47.059  39.210 1.00 62.98 ? 63  U   B "O4'"  1 
ATOM   1475 C "C3'"  . U   A 1 62  ? 22.279 47.127  40.205 1.00 62.36 ? 63  U   B "C3'"  1 
ATOM   1476 O "O3'"  . U   A 1 62  ? 23.235 48.121  40.537 1.00 64.04 ? 63  U   B "O3'"  1 
ATOM   1477 C "C2'"  . U   A 1 62  ? 21.244 46.792  41.276 1.00 63.23 ? 63  U   B "C2'"  1 
ATOM   1478 O "O2'"  . U   A 1 62  ? 20.826 47.902  42.047 1.00 62.90 ? 63  U   B "O2'"  1 
ATOM   1479 C "C1'"  . U   A 1 62  ? 20.074 46.310  40.410 1.00 61.81 ? 63  U   B "C1'"  1 
ATOM   1480 N N1     . U   A 1 62  ? 20.121 44.889  40.020 1.00 56.33 ? 63  U   B N1     1 
ATOM   1481 C C2     . U   A 1 62  ? 19.884 43.916  40.978 1.00 53.11 ? 63  U   B C2     1 
ATOM   1482 O O2     . U   A 1 62  ? 19.679 44.166  42.153 1.00 55.91 ? 63  U   B O2     1 
ATOM   1483 N N3     . U   A 1 62  ? 19.905 42.628  40.500 1.00 54.45 ? 63  U   B N3     1 
ATOM   1484 C C4     . U   A 1 62  ? 20.136 42.223  39.204 1.00 51.48 ? 63  U   B C4     1 
ATOM   1485 O O4     . U   A 1 62  ? 20.043 41.025  38.923 1.00 53.82 ? 63  U   B O4     1 
ATOM   1486 C C5     . U   A 1 62  ? 20.400 43.282  38.283 1.00 52.59 ? 63  U   B C5     1 
ATOM   1487 C C6     . U   A 1 62  ? 20.385 44.547  38.709 1.00 54.88 ? 63  U   B C6     1 
ATOM   1488 H "HO2'" . U   A 1 62  ? 20.197 47.575  42.692 1.00 20.00 ? 63  U   B "HO2'" 1 
ATOM   1489 H H3     . U   A 1 62  ? 19.745 41.889  41.166 1.00 20.00 ? 63  U   B H3     1 
ATOM   1490 P P      . C   A 1 63  ? 24.803 47.807  40.359 1.00 67.53 ? 64  C   B P      1 
ATOM   1491 O OP1    . C   A 1 63  ? 25.530 49.104  40.238 1.00 65.51 ? 64  C   B OP1    1 
ATOM   1492 O OP2    . C   A 1 63  ? 24.955 46.777  39.296 1.00 67.45 ? 64  C   B OP2    1 
ATOM   1493 O "O5'"  . C   A 1 63  ? 25.159 47.128  41.750 1.00 66.57 ? 64  C   B "O5'"  1 
ATOM   1494 C "C5'"  . C   A 1 63  ? 24.352 47.402  42.890 1.00 67.72 ? 64  C   B "C5'"  1 
ATOM   1495 C "C4'"  . C   A 1 63  ? 24.325 46.215  43.806 1.00 65.41 ? 64  C   B "C4'"  1 
ATOM   1496 O "O4'"  . C   A 1 63  ? 23.185 45.374  43.491 1.00 63.18 ? 64  C   B "O4'"  1 
ATOM   1497 C "C3'"  . C   A 1 63  ? 25.502 45.277  43.653 1.00 67.00 ? 64  C   B "C3'"  1 
ATOM   1498 O "O3'"  . C   A 1 63  ? 26.645 45.800  44.319 1.00 65.61 ? 64  C   B "O3'"  1 
ATOM   1499 C "C2'"  . C   A 1 63  ? 24.953 43.996  44.269 1.00 62.69 ? 64  C   B "C2'"  1 
ATOM   1500 O "O2'"  . C   A 1 63  ? 24.927 44.030  45.685 1.00 61.80 ? 64  C   B "O2'"  1 
ATOM   1501 C "C1'"  . C   A 1 63  ? 23.520 44.015  43.728 1.00 63.64 ? 64  C   B "C1'"  1 
ATOM   1502 N N1     . C   A 1 63  ? 23.404 43.285  42.460 1.00 58.67 ? 64  C   B N1     1 
ATOM   1503 C C2     . C   A 1 63  ? 23.256 41.903  42.500 1.00 56.31 ? 64  C   B C2     1 
ATOM   1504 O O2     . C   A 1 63  ? 23.215 41.340  43.602 1.00 54.13 ? 64  C   B O2     1 
ATOM   1505 N N3     . C   A 1 63  ? 23.166 41.215  41.339 1.00 54.44 ? 64  C   B N3     1 
ATOM   1506 C C4     . C   A 1 63  ? 23.222 41.861  40.171 1.00 54.07 ? 64  C   B C4     1 
ATOM   1507 N N4     . C   A 1 63  ? 23.142 41.140  39.055 1.00 55.40 ? 64  C   B N4     1 
ATOM   1508 C C5     . C   A 1 63  ? 23.362 43.278  40.105 1.00 58.02 ? 64  C   B C5     1 
ATOM   1509 C C6     . C   A 1 63  ? 23.445 43.944  41.262 1.00 58.28 ? 64  C   B C6     1 
ATOM   1510 H "HO2'" . C   A 1 63  ? 24.565 43.196  45.984 1.00 20.00 ? 64  C   B "HO2'" 1 
ATOM   1511 H H41    . C   A 1 63  ? 23.177 41.594  38.153 1.00 20.00 ? 64  C   B H41    1 
ATOM   1512 H H42    . C   A 1 63  ? 23.028 40.137  39.102 1.00 20.00 ? 64  C   B H42    1 
ATOM   1513 P P      . G   A 1 64  ? 28.079 45.122  44.070 1.00 62.76 ? 65  G   B P      1 
ATOM   1514 O OP1    . G   A 1 64  ? 29.108 45.931  44.786 1.00 65.29 ? 65  G   B OP1    1 
ATOM   1515 O OP2    . G   A 1 64  ? 28.220 44.886  42.606 1.00 65.13 ? 65  G   B OP2    1 
ATOM   1516 O "O5'"  . G   A 1 64  ? 27.928 43.727  44.819 1.00 62.24 ? 65  G   B "O5'"  1 
ATOM   1517 C "C5'"  . G   A 1 64  ? 28.848 42.675  44.626 1.00 55.50 ? 65  G   B "C5'"  1 
ATOM   1518 C "C4'"  . G   A 1 64  ? 28.316 41.438  45.280 1.00 50.31 ? 65  G   B "C4'"  1 
ATOM   1519 O "O4'"  . G   A 1 64  ? 26.972 41.199  44.806 1.00 47.47 ? 65  G   B "O4'"  1 
ATOM   1520 C "C3'"  . G   A 1 64  ? 29.079 40.168  44.975 1.00 47.54 ? 65  G   B "C3'"  1 
ATOM   1521 O "O3'"  . G   A 1 64  ? 30.144 40.052  45.901 1.00 43.24 ? 65  G   B "O3'"  1 
ATOM   1522 C "C2'"  . G   A 1 64  ? 28.018 39.093  45.173 1.00 44.53 ? 65  G   B "C2'"  1 
ATOM   1523 O "O2'"  . G   A 1 64  ? 27.811 38.745  46.522 1.00 40.87 ? 65  G   B "O2'"  1 
ATOM   1524 C "C1'"  . G   A 1 64  ? 26.767 39.806  44.652 1.00 45.72 ? 65  G   B "C1'"  1 
ATOM   1525 N N9     . G   A 1 64  ? 26.515 39.542  43.239 1.00 42.08 ? 65  G   B N9     1 
ATOM   1526 C C8     . G   A 1 64  ? 26.451 40.460  42.226 1.00 42.51 ? 65  G   B C8     1 
ATOM   1527 N N7     . G   A 1 64  ? 26.214 39.919  41.063 1.00 41.71 ? 65  G   B N7     1 
ATOM   1528 C C5     . G   A 1 64  ? 26.117 38.568  41.329 1.00 42.03 ? 65  G   B C5     1 
ATOM   1529 C C6     . G   A 1 64  ? 25.881 37.478  40.460 1.00 42.30 ? 65  G   B C6     1 
ATOM   1530 O O6     . G   A 1 64  ? 25.709 37.499  39.240 1.00 41.76 ? 65  G   B O6     1 
ATOM   1531 N N1     . G   A 1 64  ? 25.863 36.264  41.142 1.00 42.28 ? 65  G   B N1     1 
ATOM   1532 C C2     . G   A 1 64  ? 26.058 36.117  42.494 1.00 43.18 ? 65  G   B C2     1 
ATOM   1533 N N2     . G   A 1 64  ? 26.016 34.867  42.972 1.00 41.57 ? 65  G   B N2     1 
ATOM   1534 N N3     . G   A 1 64  ? 26.281 37.128  43.316 1.00 40.74 ? 65  G   B N3     1 
ATOM   1535 C C4     . G   A 1 64  ? 26.298 38.313  42.673 1.00 40.98 ? 65  G   B C4     1 
ATOM   1536 H "HO2'" . G   A 1 64  ? 27.145 38.057  46.532 1.00 20.00 ? 65  G   B "HO2'" 1 
ATOM   1537 H H1     . G   A 1 64  ? 25.675 35.436  40.601 1.00 20.00 ? 65  G   B H1     1 
ATOM   1538 H H21    . G   A 1 64  ? 26.169 34.694  43.957 1.00 20.00 ? 65  G   B H21    1 
ATOM   1539 H H22    . G   A 1 64  ? 25.849 34.089  42.348 1.00 20.00 ? 65  G   B H22    1 
ATOM   1540 P P      . U   A 1 65  ? 31.599 39.649  45.384 1.00 43.27 ? 66  U   B P      1 
ATOM   1541 O OP1    . U   A 1 65  ? 32.564 39.798  46.503 1.00 43.20 ? 66  U   B OP1    1 
ATOM   1542 O OP2    . U   A 1 65  ? 31.825 40.400  44.119 1.00 43.45 ? 66  U   B OP2    1 
ATOM   1543 O "O5'"  . U   A 1 65  ? 31.450 38.096  45.074 1.00 42.06 ? 66  U   B "O5'"  1 
ATOM   1544 C "C5'"  . U   A 1 65  ? 30.965 37.223  46.069 1.00 41.53 ? 66  U   B "C5'"  1 
ATOM   1545 C "C4'"  . U   A 1 65  ? 30.530 35.931  45.444 1.00 40.33 ? 66  U   B "C4'"  1 
ATOM   1546 O "O4'"  . U   A 1 65  ? 29.364 36.168  44.620 1.00 40.22 ? 66  U   B "O4'"  1 
ATOM   1547 C "C3'"  . U   A 1 65  ? 31.516 35.343  44.462 1.00 37.96 ? 66  U   B "C3'"  1 
ATOM   1548 O "O3'"  . U   A 1 65  ? 32.538 34.625  45.117 1.00 39.34 ? 66  U   B "O3'"  1 
ATOM   1549 C "C2'"  . U   A 1 65  ? 30.628 34.403  43.675 1.00 36.82 ? 66  U   B "C2'"  1 
ATOM   1550 O "O2'"  . U   A 1 65  ? 30.360 33.266  44.461 1.00 32.34 ? 66  U   B "O2'"  1 
ATOM   1551 C "C1'"  . U   A 1 65  ? 29.361 35.240  43.541 1.00 36.41 ? 66  U   B "C1'"  1 
ATOM   1552 N N1     . U   A 1 65  ? 29.273 35.987  42.276 1.00 35.84 ? 66  U   B N1     1 
ATOM   1553 C C2     . U   A 1 65  ? 28.982 35.271  41.135 1.00 34.43 ? 66  U   B C2     1 
ATOM   1554 O O2     . U   A 1 65  ? 28.830 34.072  41.136 1.00 37.14 ? 66  U   B O2     1 
ATOM   1555 N N3     . U   A 1 65  ? 28.885 36.017  39.984 1.00 35.20 ? 66  U   B N3     1 
ATOM   1556 C C4     . U   A 1 65  ? 29.053 37.386  39.865 1.00 34.70 ? 66  U   B C4     1 
ATOM   1557 O O4     . U   A 1 65  ? 28.867 37.927  38.775 1.00 37.31 ? 66  U   B O4     1 
ATOM   1558 C C5     . U   A 1 65  ? 29.370 38.057  41.089 1.00 37.15 ? 66  U   B C5     1 
ATOM   1559 C C6     . U   A 1 65  ? 29.464 37.352  42.225 1.00 35.36 ? 66  U   B C6     1 
ATOM   1560 H "HO2'" . U   A 1 65  ? 29.796 32.714  43.921 1.00 20.00 ? 66  U   B "HO2'" 1 
ATOM   1561 H H3     . U   A 1 65  ? 28.673 35.509  39.140 1.00 20.00 ? 66  U   B H3     1 
ATOM   1562 P P      . A   A 1 66  ? 33.969 34.466  44.402 1.00 39.94 ? 67  A   B P      1 
ATOM   1563 O OP1    . A   A 1 66  ? 34.914 33.830  45.349 1.00 39.07 ? 67  A   B OP1    1 
ATOM   1564 O OP2    . A   A 1 66  ? 34.320 35.767  43.772 1.00 39.40 ? 67  A   B OP2    1 
ATOM   1565 O "O5'"  . A   A 1 66  ? 33.685 33.384  43.278 1.00 40.57 ? 67  A   B "O5'"  1 
ATOM   1566 C "C5'"  . A   A 1 66  ? 33.314 32.074  43.665 1.00 41.83 ? 67  A   B "C5'"  1 
ATOM   1567 C "C4'"  . A   A 1 66  ? 33.151 31.208  42.456 1.00 40.49 ? 67  A   B "C4'"  1 
ATOM   1568 O "O4'"  . A   A 1 66  ? 31.988 31.634  41.703 1.00 40.50 ? 67  A   B "O4'"  1 
ATOM   1569 C "C3'"  . A   A 1 66  ? 34.290 31.319  41.477 1.00 39.20 ? 67  A   B "C3'"  1 
ATOM   1570 O "O3'"  . A   A 1 66  ? 35.364 30.504  41.904 1.00 36.55 ? 67  A   B "O3'"  1 
ATOM   1571 C "C2'"  . A   A 1 66  ? 33.624 30.847  40.201 1.00 38.76 ? 67  A   B "C2'"  1 
ATOM   1572 O "O2'"  . A   A 1 66  ? 33.413 29.456  40.218 1.00 37.36 ? 67  A   B "O2'"  1 
ATOM   1573 C "C1'"  . A   A 1 66  ? 32.260 31.531  40.318 1.00 39.42 ? 67  A   B "C1'"  1 
ATOM   1574 N N9     . A   A 1 66  ? 32.235 32.884  39.767 1.00 36.54 ? 67  A   B N9     1 
ATOM   1575 C C8     . A   A 1 66  ? 32.543 34.045  40.424 1.00 33.91 ? 67  A   B C8     1 
ATOM   1576 N N7     . A   A 1 66  ? 32.414 35.120  39.683 1.00 35.08 ? 67  A   B N7     1 
ATOM   1577 C C5     . A   A 1 66  ? 31.991 34.626  38.451 1.00 34.99 ? 67  A   B C5     1 
ATOM   1578 C C6     . A   A 1 66  ? 31.684 35.263  37.229 1.00 33.67 ? 67  A   B C6     1 
ATOM   1579 N N6     . A   A 1 66  ? 31.739 36.582  37.046 1.00 35.23 ? 67  A   B N6     1 
ATOM   1580 N N1     . A   A 1 66  ? 31.309 34.485  36.196 1.00 35.20 ? 67  A   B N1     1 
ATOM   1581 C C2     . A   A 1 66  ? 31.260 33.164  36.381 1.00 35.40 ? 67  A   B C2     1 
ATOM   1582 N N3     . A   A 1 66  ? 31.520 32.452  37.476 1.00 37.10 ? 67  A   B N3     1 
ATOM   1583 C C4     . A   A 1 66  ? 31.888 33.251  38.483 1.00 35.51 ? 67  A   B C4     1 
ATOM   1584 H "HO2'" . A   A 1 66  ? 32.999 29.236  39.383 1.00 20.00 ? 67  A   B "HO2'" 1 
ATOM   1585 H H61    . A   A 1 66  ? 32.044 37.181  37.803 1.00 20.00 ? 67  A   B H61    1 
ATOM   1586 H H62    . A   A 1 66  ? 31.522 36.989  36.146 1.00 20.00 ? 67  A   B H62    1 
ATOM   1587 P P      . C   A 1 67  ? 36.857 30.848  41.425 1.00 36.48 ? 68  C   B P      1 
ATOM   1588 O OP1    . C   A 1 67  ? 37.784 29.874  42.054 1.00 36.54 ? 68  C   B OP1    1 
ATOM   1589 O OP2    . C   A 1 67  ? 37.094 32.310  41.599 1.00 36.64 ? 68  C   B OP2    1 
ATOM   1590 O "O5'"  . C   A 1 67  ? 36.789 30.488  39.878 1.00 34.63 ? 68  C   B "O5'"  1 
ATOM   1591 C "C5'"  . C   A 1 67  ? 36.676 29.120  39.492 1.00 28.78 ? 68  C   B "C5'"  1 
ATOM   1592 C "C4'"  . C   A 1 67  ? 36.373 29.001  38.012 1.00 23.75 ? 68  C   B "C4'"  1 
ATOM   1593 O "O4'"  . C   A 1 67  ? 35.156 29.720  37.719 1.00 21.43 ? 68  C   B "O4'"  1 
ATOM   1594 C "C3'"  . C   A 1 67  ? 37.384 29.575  37.043 1.00 21.52 ? 68  C   B "C3'"  1 
ATOM   1595 O "O3'"  . C   A 1 67  ? 38.458 28.683  36.791 1.00 19.12 ? 68  C   B "O3'"  1 
ATOM   1596 C "C2'"  . C   A 1 67  ? 36.532 29.786  35.808 1.00 21.32 ? 68  C   B "C2'"  1 
ATOM   1597 O "O2'"  . C   A 1 67  ? 36.282 28.561  35.144 1.00 21.97 ? 68  C   B "O2'"  1 
ATOM   1598 C "C1'"  . C   A 1 67  ? 35.249 30.306  36.442 1.00 19.86 ? 68  C   B "C1'"  1 
ATOM   1599 N N1     . C   A 1 67  ? 35.252 31.757  36.633 1.00 19.98 ? 68  C   B N1     1 
ATOM   1600 C C2     . C   A 1 67  ? 34.902 32.575  35.567 1.00 19.55 ? 68  C   B C2     1 
ATOM   1601 O O2     . C   A 1 67  ? 34.647 32.055  34.480 1.00 21.01 ? 68  C   B O2     1 
ATOM   1602 N N3     . C   A 1 67  ? 34.849 33.916  35.744 1.00 21.26 ? 68  C   B N3     1 
ATOM   1603 C C4     . C   A 1 67  ? 35.140 34.434  36.936 1.00 20.95 ? 68  C   B C4     1 
ATOM   1604 N N4     . C   A 1 67  ? 35.067 35.754  37.070 1.00 21.03 ? 68  C   B N4     1 
ATOM   1605 C C5     . C   A 1 67  ? 35.535 33.624  38.037 1.00 20.75 ? 68  C   B C5     1 
ATOM   1606 C C6     . C   A 1 67  ? 35.582 32.299  37.844 1.00 20.70 ? 68  C   B C6     1 
ATOM   1607 H "HO2'" . C   A 1 67  ? 35.745 28.778  34.383 1.00 20.00 ? 68  C   B "HO2'" 1 
ATOM   1608 H H41    . C   A 1 67  ? 35.291 36.184  37.955 1.00 20.00 ? 68  C   B H41    1 
ATOM   1609 H H42    . C   A 1 67  ? 34.773 36.325  36.290 1.00 20.00 ? 68  C   B H42    1 
ATOM   1610 P P      . C   A 1 68  ? 39.921 29.283  36.552 1.00 13.09 ? 69  C   B P      1 
ATOM   1611 O OP1    . C   A 1 68  ? 40.910 28.233  36.858 1.00 11.45 ? 69  C   B OP1    1 
ATOM   1612 O OP2    . C   A 1 68  ? 39.982 30.606  37.258 1.00 11.51 ? 69  C   B OP2    1 
ATOM   1613 O "O5'"  . C   A 1 68  ? 39.973 29.595  34.991 1.00 11.73 ? 69  C   B "O5'"  1 
ATOM   1614 C "C5'"  . C   A 1 68  ? 39.358 28.710  34.052 1.00 10.48 ? 69  C   B "C5'"  1 
ATOM   1615 C "C4'"  . C   A 1 68  ? 39.238 29.383  32.693 1.00 9.86  ? 69  C   B "C4'"  1 
ATOM   1616 O "O4'"  . C   A 1 68  ? 38.073 30.246  32.666 1.00 11.39 ? 69  C   B "O4'"  1 
ATOM   1617 C "C3'"  . C   A 1 68  ? 40.379 30.298  32.298 1.00 9.32  ? 69  C   B "C3'"  1 
ATOM   1618 O "O3'"  . C   A 1 68  ? 41.420 29.529  31.713 1.00 10.16 ? 69  C   B "O3'"  1 
ATOM   1619 C "C2'"  . C   A 1 68  ? 39.721 31.191  31.258 1.00 9.84  ? 69  C   B "C2'"  1 
ATOM   1620 O "O2'"  . C   A 1 68  ? 39.541 30.531  30.027 1.00 10.11 ? 69  C   B "O2'"  1 
ATOM   1621 C "C1'"  . C   A 1 68  ? 38.338 31.381  31.866 1.00 11.17 ? 69  C   B "C1'"  1 
ATOM   1622 N N1     . C   A 1 68  ? 38.199 32.583  32.699 1.00 12.92 ? 69  C   B N1     1 
ATOM   1623 C C2     . C   A 1 68  ? 38.109 33.815  32.075 1.00 14.19 ? 69  C   B C2     1 
ATOM   1624 O O2     . C   A 1 68  ? 38.165 33.855  30.845 1.00 13.49 ? 69  C   B O2     1 
ATOM   1625 N N3     . C   A 1 68  ? 37.953 34.938  32.824 1.00 15.58 ? 69  C   B N3     1 
ATOM   1626 C C4     . C   A 1 68  ? 37.870 34.843  34.155 1.00 17.97 ? 69  C   B C4     1 
ATOM   1627 N N4     . C   A 1 68  ? 37.678 35.970  34.854 1.00 19.50 ? 69  C   B N4     1 
ATOM   1628 C C5     . C   A 1 68  ? 37.969 33.590  34.821 1.00 14.13 ? 69  C   B C5     1 
ATOM   1629 C C6     . C   A 1 68  ? 38.140 32.494  34.065 1.00 13.28 ? 69  C   B C6     1 
ATOM   1630 H "HO2'" . C   A 1 68  ? 39.138 31.170  29.439 1.00 20.00 ? 69  C   B "HO2'" 1 
ATOM   1631 H H41    . C   A 1 68  ? 37.625 35.941  35.863 1.00 20.00 ? 69  C   B H41    1 
ATOM   1632 H H42    . C   A 1 68  ? 37.588 36.857  34.381 1.00 20.00 ? 69  C   B H42    1 
ATOM   1633 P P      . C   A 1 69  ? 42.924 30.084  31.747 1.00 15.08 ? 70  C   B P      1 
ATOM   1634 O OP1    . C   A 1 69  ? 43.841 29.065  31.162 1.00 11.99 ? 70  C   B OP1    1 
ATOM   1635 O OP2    . C   A 1 69  ? 43.157 30.557  33.141 1.00 12.86 ? 70  C   B OP2    1 
ATOM   1636 O "O5'"  . C   A 1 69  ? 42.855 31.365  30.796 1.00 10.27 ? 70  C   B "O5'"  1 
ATOM   1637 C "C5'"  . C   A 1 69  ? 42.501 31.232  29.424 1.00 7.54  ? 70  C   B "C5'"  1 
ATOM   1638 C "C4'"  . C   A 1 69  ? 42.679 32.540  28.704 1.00 6.61  ? 70  C   B "C4'"  1 
ATOM   1639 O "O4'"  . C   A 1 69  ? 41.545 33.411  28.951 1.00 9.13  ? 70  C   B "O4'"  1 
ATOM   1640 C "C3'"  . C   A 1 69  ? 43.870 33.366  29.131 1.00 6.41  ? 70  C   B "C3'"  1 
ATOM   1641 O "O3'"  . C   A 1 69  ? 45.001 32.942  28.410 1.00 2.53  ? 70  C   B "O3'"  1 
ATOM   1642 C "C2'"  . C   A 1 69  ? 43.459 34.768  28.717 1.00 4.01  ? 70  C   B "C2'"  1 
ATOM   1643 O "O2'"  . C   A 1 69  ? 43.588 34.971  27.338 1.00 5.01  ? 70  C   B "O2'"  1 
ATOM   1644 C "C1'"  . C   A 1 69  ? 41.972 34.752  29.059 1.00 7.70  ? 70  C   B "C1'"  1 
ATOM   1645 N N1     . C   A 1 69  ? 41.754 35.177  30.431 1.00 9.17  ? 70  C   B N1     1 
ATOM   1646 C C2     . C   A 1 69  ? 41.628 36.526  30.689 1.00 11.59 ? 70  C   B C2     1 
ATOM   1647 O O2     . C   A 1 69  ? 41.734 37.320  29.749 1.00 12.60 ? 70  C   B O2     1 
ATOM   1648 N N3     . C   A 1 69  ? 41.400 36.941  31.953 1.00 13.15 ? 70  C   B N3     1 
ATOM   1649 C C4     . C   A 1 69  ? 41.295 36.051  32.930 1.00 10.81 ? 70  C   B C4     1 
ATOM   1650 N N4     . C   A 1 69  ? 41.021 36.497  34.141 1.00 7.39  ? 70  C   B N4     1 
ATOM   1651 C C5     . C   A 1 69  ? 41.446 34.657  32.696 1.00 12.39 ? 70  C   B C5     1 
ATOM   1652 C C6     . C   A 1 69  ? 41.665 34.267  31.442 1.00 12.29 ? 70  C   B C6     1 
ATOM   1653 H "HO2'" . C   A 1 69  ? 43.334 35.870  27.143 1.00 20.00 ? 70  C   B "HO2'" 1 
ATOM   1654 H H41    . C   A 1 69  ? 40.953 35.854  34.920 1.00 20.00 ? 70  C   B H41    1 
ATOM   1655 H H42    . C   A 1 69  ? 40.926 37.491  34.309 1.00 20.00 ? 70  C   B H42    1 
ATOM   1656 P P      . C   A 1 70  ? 46.441 33.464  28.860 1.00 5.68  ? 71  C   B P      1 
ATOM   1657 O OP1    . C   A 1 70  ? 47.418 32.915  27.908 1.00 2.00  ? 71  C   B OP1    1 
ATOM   1658 O OP2    . C   A 1 70  ? 46.592 33.205  30.324 1.00 3.12  ? 71  C   B OP2    1 
ATOM   1659 O "O5'"  . C   A 1 70  ? 46.305 35.021  28.644 1.00 2.00  ? 71  C   B "O5'"  1 
ATOM   1660 C "C5'"  . C   A 1 70  ? 46.651 35.581  27.408 1.00 2.88  ? 71  C   B "C5'"  1 
ATOM   1661 C "C4'"  . C   A 1 70  ? 46.908 37.038  27.578 1.00 3.44  ? 71  C   B "C4'"  1 
ATOM   1662 O "O4'"  . C   A 1 70  ? 45.744 37.624  28.177 1.00 2.87  ? 71  C   B "O4'"  1 
ATOM   1663 C "C3'"  . C   A 1 70  ? 48.059 37.411  28.505 1.00 2.00  ? 71  C   B "C3'"  1 
ATOM   1664 O "O3'"  . C   A 1 70  ? 49.246 37.484  27.709 1.00 6.41  ? 71  C   B "O3'"  1 
ATOM   1665 C "C2'"  . C   A 1 70  ? 47.653 38.806  28.957 1.00 2.00  ? 71  C   B "C2'"  1 
ATOM   1666 O "O2'"  . C   A 1 70  ? 48.053 39.786  28.043 1.00 2.01  ? 71  C   B "O2'"  1 
ATOM   1667 C "C1'"  . C   A 1 70  ? 46.125 38.712  28.982 1.00 2.01  ? 71  C   B "C1'"  1 
ATOM   1668 N N1     . C   A 1 70  ? 45.555 38.493  30.311 1.00 2.00  ? 71  C   B N1     1 
ATOM   1669 C C2     . C   A 1 70  ? 45.054 39.587  31.005 1.00 2.00  ? 71  C   B C2     1 
ATOM   1670 O O2     . C   A 1 70  ? 45.080 40.717  30.448 1.00 2.00  ? 71  C   B O2     1 
ATOM   1671 N N3     . C   A 1 70  ? 44.553 39.406  32.249 1.00 2.00  ? 71  C   B N3     1 
ATOM   1672 C C4     . C   A 1 70  ? 44.530 38.184  32.777 1.00 2.00  ? 71  C   B C4     1 
ATOM   1673 N N4     . C   A 1 70  ? 44.006 38.057  33.990 1.00 4.60  ? 71  C   B N4     1 
ATOM   1674 C C5     . C   A 1 70  ? 45.029 37.048  32.087 1.00 2.01  ? 71  C   B C5     1 
ATOM   1675 C C6     . C   A 1 70  ? 45.526 37.243  30.868 1.00 2.01  ? 71  C   B C6     1 
ATOM   1676 H "HO2'" . C   A 1 70  ? 47.784 40.629  28.415 1.00 20.00 ? 71  C   B "HO2'" 1 
ATOM   1677 H H41    . C   A 1 70  ? 43.955 37.147  34.430 1.00 20.00 ? 71  C   B H41    1 
ATOM   1678 H H42    . C   A 1 70  ? 43.640 38.862  34.473 1.00 20.00 ? 71  C   B H42    1 
ATOM   1679 P P      . A   A 1 71  ? 50.688 37.117  28.333 1.00 12.88 ? 72  A   B P      1 
ATOM   1680 O OP1    . A   A 1 71  ? 51.553 36.942  27.155 1.00 13.81 ? 72  A   B OP1    1 
ATOM   1681 O OP2    . A   A 1 71  ? 50.537 36.009  29.297 1.00 15.16 ? 72  A   B OP2    1 
ATOM   1682 O "O5'"  . A   A 1 71  ? 51.135 38.388  29.166 1.00 9.62  ? 72  A   B "O5'"  1 
ATOM   1683 C "C5'"  . A   A 1 71  ? 51.491 39.591  28.526 1.00 12.64 ? 72  A   B "C5'"  1 
ATOM   1684 C "C4'"  . A   A 1 71  ? 52.350 40.421  29.450 1.00 12.75 ? 72  A   B "C4'"  1 
ATOM   1685 O "O4'"  . A   A 1 71  ? 51.562 40.910  30.569 1.00 14.21 ? 72  A   B "O4'"  1 
ATOM   1686 C "C3'"  . A   A 1 71  ? 53.492 39.677  30.103 1.00 10.02 ? 72  A   B "C3'"  1 
ATOM   1687 O "O3'"  . A   A 1 71  ? 54.631 39.685  29.290 1.00 8.35  ? 72  A   B "O3'"  1 
ATOM   1688 C "C2'"  . A   A 1 71  ? 53.762 40.511  31.332 1.00 13.42 ? 72  A   B "C2'"  1 
ATOM   1689 O "O2'"  . A   A 1 71  ? 54.460 41.686  31.000 1.00 14.82 ? 72  A   B "O2'"  1 
ATOM   1690 C "C1'"  . A   A 1 71  ? 52.342 40.879  31.740 1.00 16.64 ? 72  A   B "C1'"  1 
ATOM   1691 N N9     . A   A 1 71  ? 51.740 39.920  32.651 1.00 21.11 ? 72  A   B N9     1 
ATOM   1692 C C8     . A   A 1 71  ? 50.743 39.019  32.404 1.00 22.50 ? 72  A   B C8     1 
ATOM   1693 N N7     . A   A 1 71  ? 50.335 38.381  33.477 1.00 27.83 ? 72  A   B N7     1 
ATOM   1694 C C5     . A   A 1 71  ? 51.144 38.884  34.486 1.00 27.68 ? 72  A   B C5     1 
ATOM   1695 C C6     . A   A 1 71  ? 51.191 38.649  35.875 1.00 28.17 ? 72  A   B C6     1 
ATOM   1696 N N6     . A   A 1 71  ? 50.358 37.838  36.511 1.00 33.34 ? 72  A   B N6     1 
ATOM   1697 N N1     . A   A 1 71  ? 52.122 39.301  36.595 1.00 31.34 ? 72  A   B N1     1 
ATOM   1698 C C2     . A   A 1 71  ? 52.932 40.146  35.961 1.00 32.15 ? 72  A   B C2     1 
ATOM   1699 N N3     . A   A 1 71  ? 52.973 40.473  34.672 1.00 30.13 ? 72  A   B N3     1 
ATOM   1700 C C4     . A   A 1 71  ? 52.038 39.802  33.986 1.00 25.37 ? 72  A   B C4     1 
ATOM   1701 H "HO2'" . A   A 1 71  ? 54.585 42.191  31.804 1.00 20.00 ? 72  A   B "HO2'" 1 
ATOM   1702 H H61    . A   A 1 71  ? 49.628 37.359  36.000 1.00 20.00 ? 72  A   B H61    1 
ATOM   1703 H H62    . A   A 1 71  ? 50.436 37.718  37.511 1.00 20.00 ? 72  A   B H62    1 
ATOM   1704 P P      . G   A 1 72  ? 55.666 38.479  29.382 1.00 9.65  ? 73  G   B P      1 
ATOM   1705 O OP1    . G   A 1 72  ? 55.321 37.604  30.532 1.00 6.22  ? 73  G   B OP1    1 
ATOM   1706 O OP2    . G   A 1 72  ? 57.017 39.053  29.285 1.00 10.39 ? 73  G   B OP2    1 
ATOM   1707 O "O5'"  . G   A 1 72  ? 55.466 37.717  28.015 1.00 9.14  ? 73  G   B "O5'"  1 
ATOM   1708 C "C5'"  . G   A 1 72  ? 55.428 38.459  26.801 1.00 11.45 ? 73  G   B "C5'"  1 
ATOM   1709 C "C4'"  . G   A 1 72  ? 56.332 37.830  25.777 1.00 10.10 ? 73  G   B "C4'"  1 
ATOM   1710 O "O4'"  . G   A 1 72  ? 56.117 36.425  25.698 1.00 10.26 ? 73  G   B "O4'"  1 
ATOM   1711 C "C3'"  . G   A 1 72  ? 56.162 38.357  24.359 1.00 9.52  ? 73  G   B "C3'"  1 
ATOM   1712 O "O3'"  . G   A 1 72  ? 57.380 39.024  24.074 1.00 6.67  ? 73  G   B "O3'"  1 
ATOM   1713 C "C2'"  . G   A 1 72  ? 56.250 37.122  23.460 1.00 11.42 ? 73  G   B "C2'"  1 
ATOM   1714 O "O2'"  . G   A 1 72  ? 57.284 37.245  22.507 1.00 14.63 ? 73  G   B "O2'"  1 
ATOM   1715 C "C1'"  . G   A 1 72  ? 56.592 36.016  24.462 1.00 8.60  ? 73  G   B "C1'"  1 
ATOM   1716 N N9     . G   A 1 72  ? 56.234 34.631  24.216 1.00 7.56  ? 73  G   B N9     1 
ATOM   1717 C C8     . G   A 1 72  ? 56.972 33.711  23.519 1.00 8.88  ? 73  G   B C8     1 
ATOM   1718 N N7     . G   A 1 72  ? 56.421 32.534  23.492 1.00 10.09 ? 73  G   B N7     1 
ATOM   1719 C C5     . G   A 1 72  ? 55.254 32.700  24.200 1.00 7.72  ? 73  G   B C5     1 
ATOM   1720 C C6     . G   A 1 72  ? 54.274 31.780  24.514 1.00 9.03  ? 73  G   B C6     1 
ATOM   1721 O O6     . G   A 1 72  ? 54.207 30.592  24.174 1.00 9.98  ? 73  G   B O6     1 
ATOM   1722 N N1     . G   A 1 72  ? 53.278 32.349  25.297 1.00 4.81  ? 73  G   B N1     1 
ATOM   1723 C C2     . G   A 1 72  ? 53.239 33.660  25.704 1.00 3.31  ? 73  G   B C2     1 
ATOM   1724 N N2     . G   A 1 72  ? 52.186 34.040  26.466 1.00 2.43  ? 73  G   B N2     1 
ATOM   1725 N N3     . G   A 1 72  ? 54.154 34.534  25.388 1.00 4.95  ? 73  G   B N3     1 
ATOM   1726 C C4     . G   A 1 72  ? 55.128 33.992  24.652 1.00 7.63  ? 73  G   B C4     1 
ATOM   1727 H "HO2'" . G   A 1 72  ? 57.272 36.450  21.972 1.00 20.00 ? 73  G   B "HO2'" 1 
ATOM   1728 H H1     . G   A 1 72  ? 52.533 31.742  25.612 1.00 20.00 ? 73  G   B H1     1 
ATOM   1729 H H21    . G   A 1 72  ? 52.122 34.994  26.793 1.00 20.00 ? 73  G   B H21    1 
ATOM   1730 H H22    . G   A 1 72  ? 51.472 33.370  26.727 1.00 20.00 ? 73  G   B H22    1 
ATOM   1731 P P      . C   A 1 73  ? 57.453 40.600  23.985 1.00 4.00  ? 74  C   B P      1 
ATOM   1732 O OP1    . C   A 1 73  ? 58.449 41.015  25.008 1.00 4.97  ? 74  C   B OP1    1 
ATOM   1733 O OP2    . C   A 1 73  ? 56.058 41.122  24.026 1.00 7.23  ? 74  C   B OP2    1 
ATOM   1734 O "O5'"  . C   A 1 73  ? 58.055 40.843  22.539 1.00 2.00  ? 74  C   B "O5'"  1 
ATOM   1735 C "C5'"  . C   A 1 73  ? 57.628 40.049  21.442 1.00 2.00  ? 74  C   B "C5'"  1 
ATOM   1736 C "C4'"  . C   A 1 73  ? 58.817 39.682  20.606 1.00 2.00  ? 74  C   B "C4'"  1 
ATOM   1737 O "O4'"  . C   A 1 73  ? 59.814 40.694  20.688 1.00 4.39  ? 74  C   B "O4'"  1 
ATOM   1738 C "C3'"  . C   A 1 73  ? 59.464 38.359  20.986 1.00 2.01  ? 74  C   B "C3'"  1 
ATOM   1739 O "O3'"  . C   A 1 73  ? 59.099 37.593  19.819 1.00 2.00  ? 74  C   B "O3'"  1 
ATOM   1740 C "C2'"  . C   A 1 73  ? 60.964 38.651  21.029 1.00 2.01  ? 74  C   B "C2'"  1 
ATOM   1741 O "O2'"  . C   A 1 73  ? 61.719 37.844  20.166 1.00 3.30  ? 74  C   B "O2'"  1 
ATOM   1742 C "C1'"  . C   A 1 73  ? 61.060 40.099  20.548 1.00 2.01  ? 74  C   B "C1'"  1 
ATOM   1743 N N1     . C   A 1 73  ? 62.054 41.005  21.109 1.00 2.01  ? 74  C   B N1     1 
ATOM   1744 C C2     . C   A 1 73  ? 63.306 41.123  20.500 1.00 2.00  ? 74  C   B C2     1 
ATOM   1745 O O2     . C   A 1 73  ? 63.584 40.386  19.524 1.00 2.00  ? 74  C   B O2     1 
ATOM   1746 N N3     . C   A 1 73  ? 64.185 42.029  20.977 1.00 2.00  ? 74  C   B N3     1 
ATOM   1747 C C4     . C   A 1 73  ? 63.860 42.788  22.022 1.00 2.00  ? 74  C   B C4     1 
ATOM   1748 N N4     . C   A 1 73  ? 64.760 43.677  22.467 1.00 2.01  ? 74  C   B N4     1 
ATOM   1749 C C5     . C   A 1 73  ? 62.605 42.667  22.675 1.00 3.46  ? 74  C   B C5     1 
ATOM   1750 C C6     . C   A 1 73  ? 61.747 41.763  22.196 1.00 3.18  ? 74  C   B C6     1 
ATOM   1751 H "HO2'" . C   A 1 73  ? 62.631 38.116  20.281 1.00 20.00 ? 74  C   B "HO2'" 1 
ATOM   1752 H H41    . C   A 1 73  ? 64.536 44.278  23.246 1.00 20.00 ? 74  C   B H41    1 
ATOM   1753 H H42    . C   A 1 73  ? 65.643 43.764  21.992 1.00 20.00 ? 74  C   B H42    1 
ATOM   1754 P P      . C   A 1 74  ? 59.439 36.019  19.686 1.00 2.01  ? 75  C   B P      1 
ATOM   1755 O OP1    . C   A 1 74  ? 60.506 35.608  20.631 1.00 2.00  ? 75  C   B OP1    1 
ATOM   1756 O OP2    . C   A 1 74  ? 59.582 35.708  18.243 1.00 2.01  ? 75  C   B OP2    1 
ATOM   1757 O "O5'"  . C   A 1 74  ? 58.085 35.380  20.184 1.00 2.00  ? 75  C   B "O5'"  1 
ATOM   1758 C "C5'"  . C   A 1 74  ? 56.907 35.517  19.414 1.00 2.01  ? 75  C   B "C5'"  1 
ATOM   1759 C "C4'"  . C   A 1 74  ? 56.379 34.158  19.105 1.00 2.00  ? 75  C   B "C4'"  1 
ATOM   1760 O "O4'"  . C   A 1 74  ? 56.104 33.508  20.356 1.00 2.00  ? 75  C   B "O4'"  1 
ATOM   1761 C "C3'"  . C   A 1 74  ? 55.076 34.081  18.339 1.00 2.00  ? 75  C   B "C3'"  1 
ATOM   1762 O "O3'"  . C   A 1 74  ? 55.382 34.096  16.947 1.00 2.01  ? 75  C   B "O3'"  1 
ATOM   1763 C "C2'"  . C   A 1 74  ? 54.581 32.701  18.735 1.00 2.00  ? 75  C   B "C2'"  1 
ATOM   1764 O "O2'"  . C   A 1 74  ? 55.239 31.701  17.981 1.00 2.01  ? 75  C   B "O2'"  1 
ATOM   1765 C "C1'"  . C   A 1 74  ? 55.023 32.627  20.203 1.00 2.01  ? 75  C   B "C1'"  1 
ATOM   1766 N N1     . C   A 1 74  ? 53.976 33.052  21.125 1.00 2.01  ? 75  C   B N1     1 
ATOM   1767 C C2     . C   A 1 74  ? 52.966 32.168  21.412 1.00 2.85  ? 75  C   B C2     1 
ATOM   1768 O O2     . C   A 1 74  ? 53.071 31.014  20.981 1.00 4.86  ? 75  C   B O2     1 
ATOM   1769 N N3     . C   A 1 74  ? 51.913 32.571  22.165 1.00 2.01  ? 75  C   B N3     1 
ATOM   1770 C C4     . C   A 1 74  ? 51.892 33.808  22.649 1.00 2.00  ? 75  C   B C4     1 
ATOM   1771 N N4     . C   A 1 74  ? 50.832 34.192  23.369 1.00 2.00  ? 75  C   B N4     1 
ATOM   1772 C C5     . C   A 1 74  ? 52.965 34.722  22.414 1.00 2.83  ? 75  C   B C5     1 
ATOM   1773 C C6     . C   A 1 74  ? 53.974 34.306  21.658 1.00 2.01  ? 75  C   B C6     1 
ATOM   1774 H "HO2'" . C   A 1 74  ? 54.891 30.862  18.288 1.00 20.00 ? 75  C   B "HO2'" 1 
ATOM   1775 H H41    . C   A 1 74  ? 50.811 35.116  23.771 1.00 20.00 ? 75  C   B H41    1 
ATOM   1776 H H42    . C   A 1 74  ? 50.072 33.543  23.552 1.00 20.00 ? 75  C   B H42    1 
ATOM   1777 P P      . A   A 1 75  ? 54.465 34.947  15.942 1.00 2.01  ? 76  A   B P      1 
ATOM   1778 O OP1    . A   A 1 75  ? 55.134 34.967  14.625 1.00 2.00  ? 76  A   B OP1    1 
ATOM   1779 O OP2    . A   A 1 75  ? 54.159 36.215  16.627 1.00 2.00  ? 76  A   B OP2    1 
ATOM   1780 O "O5'"  . A   A 1 75  ? 53.109 34.128  15.857 1.00 2.01  ? 76  A   B "O5'"  1 
ATOM   1781 C "C5'"  . A   A 1 75  ? 53.092 32.787  15.380 1.00 2.00  ? 76  A   B "C5'"  1 
ATOM   1782 C "C4'"  . A   A 1 75  ? 51.810 32.107  15.791 1.00 2.00  ? 76  A   B "C4'"  1 
ATOM   1783 O "O4'"  . A   A 1 75  ? 51.713 32.168  17.239 1.00 4.11  ? 76  A   B "O4'"  1 
ATOM   1784 C "C3'"  . A   A 1 75  ? 50.537 32.812  15.358 1.00 2.01  ? 76  A   B "C3'"  1 
ATOM   1785 O "O3'"  . A   A 1 75  ? 50.120 32.660  14.000 1.00 2.01  ? 76  A   B "O3'"  1 
ATOM   1786 C "C2'"  . A   A 1 75  ? 49.536 32.242  16.339 1.00 2.01  ? 76  A   B "C2'"  1 
ATOM   1787 O "O2'"  . A   A 1 75  ? 49.254 30.899  16.028 1.00 2.00  ? 76  A   B "O2'"  1 
ATOM   1788 C "C1'"  . A   A 1 75  ? 50.350 32.266  17.626 1.00 2.00  ? 76  A   B "C1'"  1 
ATOM   1789 N N9     . A   A 1 75  ? 50.192 33.488  18.416 1.00 2.00  ? 76  A   B N9     1 
ATOM   1790 C C8     . A   A 1 75  ? 50.914 34.642  18.300 1.00 2.00  ? 76  A   B C8     1 
ATOM   1791 N N7     . A   A 1 75  ? 50.587 35.565  19.163 1.00 2.00  ? 76  A   B N7     1 
ATOM   1792 C C5     . A   A 1 75  ? 49.570 34.986  19.894 1.00 2.01  ? 76  A   B C5     1 
ATOM   1793 C C6     . A   A 1 75  ? 48.813 35.448  20.972 1.00 2.00  ? 76  A   B C6     1 
ATOM   1794 N N6     . A   A 1 75  ? 48.978 36.647  21.523 1.00 2.00  ? 76  A   B N6     1 
ATOM   1795 N N1     . A   A 1 75  ? 47.879 34.628  21.489 1.00 2.00  ? 76  A   B N1     1 
ATOM   1796 C C2     . A   A 1 75  ? 47.727 33.419  20.944 1.00 2.00  ? 76  A   B C2     1 
ATOM   1797 N N3     . A   A 1 75  ? 48.383 32.869  19.917 1.00 2.00  ? 76  A   B N3     1 
ATOM   1798 C C4     . A   A 1 75  ? 49.301 33.708  19.435 1.00 2.01  ? 76  A   B C4     1 
ATOM   1799 H "HO3'" . A   A 1 75  ? 49.292 33.125  13.875 1.00 20.00 ? 76  A   B "HO3'" 1 
ATOM   1800 H "HO2'" . A   A 1 75  ? 48.603 30.618  16.674 1.00 20.00 ? 76  A   B "HO2'" 1 
ATOM   1801 H H61    . A   A 1 75  ? 49.692 37.267  21.171 1.00 20.00 ? 76  A   B H61    1 
ATOM   1802 H H62    . A   A 1 75  ? 48.408 36.935  22.308 1.00 20.00 ? 76  A   B H62    1 
ATOM   1803 N N      . THR B 2 8   ? 22.158 26.609  13.812 1.00 27.02 ? 8   THR A N      1 
ATOM   1804 C CA     . THR B 2 8   ? 22.612 27.991  13.756 1.00 27.64 ? 8   THR A CA     1 
ATOM   1805 C C      . THR B 2 8   ? 23.304 28.308  15.062 1.00 27.58 ? 8   THR A C      1 
ATOM   1806 O O      . THR B 2 8   ? 22.981 27.725  16.108 1.00 29.68 ? 8   THR A O      1 
ATOM   1807 C CB     . THR B 2 8   ? 21.438 29.006  13.542 1.00 28.60 ? 8   THR A CB     1 
ATOM   1808 O OG1    . THR B 2 8   ? 21.901 30.116  12.763 1.00 26.88 ? 8   THR A OG1    1 
ATOM   1809 C CG2    . THR B 2 8   ? 20.912 29.550  14.878 1.00 29.98 ? 8   THR A CG2    1 
ATOM   1810 H H      . THR B 2 8   ? 21.988 26.186  14.707 1.00 20.00 ? 8   THR A H      1 
ATOM   1811 H HG1    . THR B 2 8   ? 21.191 30.743  12.624 1.00 20.00 ? 8   THR A HG1    1 
ATOM   1812 N N      . ASN B 2 9   ? 24.268 29.217  14.991 1.00 23.07 ? 9   ASN A N      1 
ATOM   1813 C CA     . ASN B 2 9   ? 25.025 29.632  16.157 1.00 17.41 ? 9   ASN A CA     1 
ATOM   1814 C C      . ASN B 2 9   ? 25.151 31.142  16.116 1.00 13.90 ? 9   ASN A C      1 
ATOM   1815 O O      . ASN B 2 9   ? 24.641 31.772  15.183 1.00 12.66 ? 9   ASN A O      1 
ATOM   1816 C CB     . ASN B 2 9   ? 26.388 28.979  16.147 1.00 17.40 ? 9   ASN A CB     1 
ATOM   1817 C CG     . ASN B 2 9   ? 27.070 29.099  14.821 1.00 19.65 ? 9   ASN A CG     1 
ATOM   1818 O OD1    . ASN B 2 9   ? 27.308 30.201  14.329 1.00 20.92 ? 9   ASN A OD1    1 
ATOM   1819 N ND2    . ASN B 2 9   ? 27.378 27.965  14.214 1.00 19.15 ? 9   ASN A ND2    1 
ATOM   1820 H H      . ASN B 2 9   ? 24.450 29.640  14.132 1.00 20.00 ? 9   ASN A H      1 
ATOM   1821 H HD21   . ASN B 2 9   ? 27.816 28.019  13.352 1.00 20.00 ? 9   ASN A HD21   1 
ATOM   1822 H HD22   . ASN B 2 9   ? 27.140 27.107  14.643 1.00 20.00 ? 9   ASN A HD22   1 
ATOM   1823 N N      . PHE B 2 10  ? 25.824 31.730  17.104 1.00 9.54  ? 10  PHE A N      1 
ATOM   1824 C CA     . PHE B 2 10  ? 25.936 33.188  17.158 1.00 4.15  ? 10  PHE A CA     1 
ATOM   1825 C C      . PHE B 2 10  ? 26.667 33.779  15.999 1.00 3.39  ? 10  PHE A C      1 
ATOM   1826 O O      . PHE B 2 10  ? 26.333 34.879  15.573 1.00 6.47  ? 10  PHE A O      1 
ATOM   1827 C CB     . PHE B 2 10  ? 26.554 33.696  18.473 1.00 2.00  ? 10  PHE A CB     1 
ATOM   1828 C CG     . PHE B 2 10  ? 28.053 33.563  18.563 1.00 2.00  ? 10  PHE A CG     1 
ATOM   1829 C CD1    . PHE B 2 10  ? 28.666 32.321  18.784 1.00 2.00  ? 10  PHE A CD1    1 
ATOM   1830 C CD2    . PHE B 2 10  ? 28.853 34.700  18.504 1.00 2.01  ? 10  PHE A CD2    1 
ATOM   1831 C CE1    . PHE B 2 10  ? 30.055 32.224  18.943 1.00 2.00  ? 10  PHE A CE1    1 
ATOM   1832 C CE2    . PHE B 2 10  ? 30.238 34.625  18.659 1.00 2.01  ? 10  PHE A CE2    1 
ATOM   1833 C CZ     . PHE B 2 10  ? 30.842 33.394  18.881 1.00 2.01  ? 10  PHE A CZ     1 
ATOM   1834 H H      . PHE B 2 10  ? 26.236 31.177  17.798 1.00 20.00 ? 10  PHE A H      1 
ATOM   1835 N N      . ILE B 2 11  ? 27.652 33.060  15.473 1.00 4.01  ? 11  ILE A N      1 
ATOM   1836 C CA     . ILE B 2 11  ? 28.414 33.591  14.365 1.00 4.88  ? 11  ILE A CA     1 
ATOM   1837 C C      . ILE B 2 11  ? 27.578 33.678  13.107 1.00 5.95  ? 11  ILE A C      1 
ATOM   1838 O O      . ILE B 2 11  ? 27.690 34.658  12.370 1.00 3.52  ? 11  ILE A O      1 
ATOM   1839 C CB     . ILE B 2 11  ? 29.690 32.811  14.126 1.00 3.69  ? 11  ILE A CB     1 
ATOM   1840 C CG1    . ILE B 2 11  ? 30.591 32.986  15.338 1.00 2.01  ? 11  ILE A CG1    1 
ATOM   1841 C CG2    . ILE B 2 11  ? 30.371 33.323  12.874 1.00 2.00  ? 11  ILE A CG2    1 
ATOM   1842 C CD1    . ILE B 2 11  ? 31.806 32.162  15.303 1.00 2.01  ? 11  ILE A CD1    1 
ATOM   1843 H H      . ILE B 2 11  ? 27.842 32.148  15.796 1.00 20.00 ? 11  ILE A H      1 
ATOM   1844 N N      . ARG B 2 12  ? 26.648 32.737  12.928 1.00 11.39 ? 12  ARG A N      1 
ATOM   1845 C CA     . ARG B 2 12  ? 25.795 32.736  11.740 1.00 13.70 ? 12  ARG A CA     1 
ATOM   1846 C C      . ARG B 2 12  ? 24.693 33.752  11.821 1.00 14.17 ? 12  ARG A C      1 
ATOM   1847 O O      . ARG B 2 12  ? 24.239 34.241  10.804 1.00 14.96 ? 12  ARG A O      1 
ATOM   1848 C CB     . ARG B 2 12  ? 25.267 31.336  11.428 1.00 13.95 ? 12  ARG A CB     1 
ATOM   1849 C CG     . ARG B 2 12  ? 26.415 30.431  11.016 1.00 16.16 ? 12  ARG A CG     1 
ATOM   1850 C CD     . ARG B 2 12  ? 26.094 28.963  10.997 1.00 17.50 ? 12  ARG A CD     1 
ATOM   1851 N NE     . ARG B 2 12  ? 25.549 28.524  9.718  1.00 19.49 ? 12  ARG A NE     1 
ATOM   1852 C CZ     . ARG B 2 12  ? 26.102 27.586  8.952  1.00 19.17 ? 12  ARG A CZ     1 
ATOM   1853 N NH1    . ARG B 2 12  ? 27.241 27.004  9.311  1.00 18.63 ? 12  ARG A NH1    1 
ATOM   1854 N NH2    . ARG B 2 12  ? 25.520 27.247  7.810  1.00 18.15 ? 12  ARG A NH2    1 
ATOM   1855 H H      . ARG B 2 12  ? 26.546 32.033  13.587 1.00 20.00 ? 12  ARG A H      1 
ATOM   1856 H HE     . ARG B 2 12  ? 24.721 28.945  9.421  1.00 20.00 ? 12  ARG A HE     1 
ATOM   1857 H HH11   . ARG B 2 12  ? 27.708 27.276  10.148 1.00 20.00 ? 12  ARG A HH11   1 
ATOM   1858 H HH12   . ARG B 2 12  ? 27.656 26.322  8.704  1.00 20.00 ? 12  ARG A HH12   1 
ATOM   1859 H HH21   . ARG B 2 12  ? 24.674 27.711  7.530  1.00 20.00 ? 12  ARG A HH21   1 
ATOM   1860 H HH22   . ARG B 2 12  ? 25.915 26.581  7.234  1.00 20.00 ? 12  ARG A HH22   1 
ATOM   1861 N N      . GLN B 2 13  ? 24.301 34.129  13.026 1.00 15.09 ? 13  GLN A N      1 
ATOM   1862 C CA     . GLN B 2 13  ? 23.250 35.118  13.144 1.00 15.96 ? 13  GLN A CA     1 
ATOM   1863 C C      . GLN B 2 13  ? 23.869 36.445  12.752 1.00 8.53  ? 13  GLN A C      1 
ATOM   1864 O O      . GLN B 2 13  ? 23.253 37.242  12.060 1.00 7.36  ? 13  GLN A O      1 
ATOM   1865 C CB     . GLN B 2 13  ? 22.669 35.120  14.562 1.00 23.82 ? 13  GLN A CB     1 
ATOM   1866 C CG     . GLN B 2 13  ? 21.826 33.862  14.834 1.00 31.43 ? 13  GLN A CG     1 
ATOM   1867 C CD     . GLN B 2 13  ? 21.580 33.589  16.308 1.00 36.96 ? 13  GLN A CD     1 
ATOM   1868 O OE1    . GLN B 2 13  ? 21.427 34.507  17.117 1.00 36.58 ? 13  GLN A OE1    1 
ATOM   1869 N NE2    . GLN B 2 13  ? 21.535 32.317  16.664 1.00 37.98 ? 13  GLN A NE2    1 
ATOM   1870 H H      . GLN B 2 13  ? 24.699 33.732  13.834 1.00 20.00 ? 13  GLN A H      1 
ATOM   1871 H HE21   . GLN B 2 13  ? 21.370 32.131  17.609 1.00 20.00 ? 13  GLN A HE21   1 
ATOM   1872 H HE22   . GLN B 2 13  ? 21.643 31.628  15.993 1.00 20.00 ? 13  GLN A HE22   1 
ATOM   1873 N N      . ILE B 2 14  ? 25.143 36.604  13.071 1.00 2.61  ? 14  ILE A N      1 
ATOM   1874 C CA     . ILE B 2 14  ? 25.862 37.819  12.729 1.00 2.00  ? 14  ILE A CA     1 
ATOM   1875 C C      . ILE B 2 14  ? 25.991 37.904  11.223 1.00 2.00  ? 14  ILE A C      1 
ATOM   1876 O O      . ILE B 2 14  ? 25.725 38.937  10.619 1.00 2.00  ? 14  ILE A O      1 
ATOM   1877 C CB     . ILE B 2 14  ? 27.269 37.822  13.352 1.00 2.00  ? 14  ILE A CB     1 
ATOM   1878 C CG1    . ILE B 2 14  ? 27.216 38.373  14.771 1.00 2.01  ? 14  ILE A CG1    1 
ATOM   1879 C CG2    . ILE B 2 14  ? 28.236 38.600  12.492 1.00 2.01  ? 14  ILE A CG2    1 
ATOM   1880 C CD1    . ILE B 2 14  ? 28.455 38.168  15.500 1.00 2.01  ? 14  ILE A CD1    1 
ATOM   1881 H H      . ILE B 2 14  ? 25.615 35.893  13.556 1.00 20.00 ? 14  ILE A H      1 
ATOM   1882 N N      . ILE B 2 15  ? 26.363 36.789  10.611 1.00 2.36  ? 15  ILE A N      1 
ATOM   1883 C CA     . ILE B 2 15  ? 26.523 36.748  9.169  1.00 4.20  ? 15  ILE A CA     1 
ATOM   1884 C C      . ILE B 2 15  ? 25.194 37.018  8.488  1.00 6.14  ? 15  ILE A C      1 
ATOM   1885 O O      . ILE B 2 15  ? 25.135 37.823  7.558  1.00 6.63  ? 15  ILE A O      1 
ATOM   1886 C CB     . ILE B 2 15  ? 27.178 35.416  8.709  1.00 2.00  ? 15  ILE A CB     1 
ATOM   1887 C CG1    . ILE B 2 15  ? 28.614 35.377  9.225  1.00 2.01  ? 15  ILE A CG1    1 
ATOM   1888 C CG2    . ILE B 2 15  ? 27.121 35.281  7.203  1.00 2.00  ? 15  ILE A CG2    1 
ATOM   1889 C CD1    . ILE B 2 15  ? 29.399 34.170  8.798  1.00 2.01  ? 15  ILE A CD1    1 
ATOM   1890 H H      . ILE B 2 15  ? 26.572 35.987  11.144 1.00 20.00 ? 15  ILE A H      1 
ATOM   1891 N N      . ASP B 2 16  ? 24.119 36.443  9.010  1.00 10.02 ? 16  ASP A N      1 
ATOM   1892 C CA     . ASP B 2 16  ? 22.813 36.650  8.407  1.00 17.54 ? 16  ASP A CA     1 
ATOM   1893 C C      . ASP B 2 16  ? 22.467 38.137  8.425  1.00 21.26 ? 16  ASP A C      1 
ATOM   1894 O O      . ASP B 2 16  ? 22.067 38.720  7.408  1.00 20.11 ? 16  ASP A O      1 
ATOM   1895 C CB     . ASP B 2 16  ? 21.759 35.828  9.136  1.00 19.59 ? 16  ASP A CB     1 
ATOM   1896 C CG     . ASP B 2 16  ? 21.880 34.355  8.853  1.00 21.21 ? 16  ASP A CG     1 
ATOM   1897 O OD1    . ASP B 2 16  ? 22.420 33.971  7.800  1.00 25.52 ? 16  ASP A OD1    1 
ATOM   1898 O OD2    . ASP B 2 16  ? 21.420 33.557  9.681  1.00 23.05 ? 16  ASP A OD2    1 
ATOM   1899 H H      . ASP B 2 16  ? 24.208 35.860  9.780  1.00 20.00 ? 16  ASP A H      1 
ATOM   1900 N N      . GLU B 2 17  ? 22.684 38.760  9.573  1.00 24.98 ? 17  GLU A N      1 
ATOM   1901 C CA     . GLU B 2 17  ? 22.420 40.174  9.706  1.00 25.56 ? 17  GLU A CA     1 
ATOM   1902 C C      . GLU B 2 17  ? 23.261 40.924  8.689  1.00 22.56 ? 17  GLU A C      1 
ATOM   1903 O O      . GLU B 2 17  ? 22.737 41.759  7.963  1.00 21.70 ? 17  GLU A O      1 
ATOM   1904 C CB     . GLU B 2 17  ? 22.771 40.655  11.113 1.00 30.90 ? 17  GLU A CB     1 
ATOM   1905 C CG     . GLU B 2 17  ? 21.806 40.169  12.195 1.00 35.79 ? 17  GLU A CG     1 
ATOM   1906 C CD     . GLU B 2 17  ? 22.290 40.455  13.623 1.00 40.84 ? 17  GLU A CD     1 
ATOM   1907 O OE1    . GLU B 2 17  ? 23.283 41.199  13.797 1.00 38.93 ? 17  GLU A OE1    1 
ATOM   1908 O OE2    . GLU B 2 17  ? 21.676 39.925  14.582 1.00 40.62 ? 17  GLU A OE2    1 
ATOM   1909 H H      . GLU B 2 17  ? 23.027 38.254  10.340 1.00 20.00 ? 17  GLU A H      1 
ATOM   1910 N N      . ASP B 2 18  ? 24.540 40.572  8.578  1.00 19.91 ? 18  ASP A N      1 
ATOM   1911 C CA     . ASP B 2 18  ? 25.420 41.259  7.649  1.00 19.40 ? 18  ASP A CA     1 
ATOM   1912 C C      . ASP B 2 18  ? 24.917 41.211  6.224  1.00 18.05 ? 18  ASP A C      1 
ATOM   1913 O O      . ASP B 2 18  ? 24.917 42.233  5.537  1.00 19.12 ? 18  ASP A O      1 
ATOM   1914 C CB     . ASP B 2 18  ? 26.860 40.740  7.751  1.00 22.24 ? 18  ASP A CB     1 
ATOM   1915 C CG     . ASP B 2 18  ? 27.618 41.342  8.946  1.00 22.13 ? 18  ASP A CG     1 
ATOM   1916 O OD1    . ASP B 2 18  ? 27.007 42.090  9.744  1.00 25.86 ? 18  ASP A OD1    1 
ATOM   1917 O OD2    . ASP B 2 18  ? 28.833 41.085  9.092  1.00 20.07 ? 18  ASP A OD2    1 
ATOM   1918 H H      . ASP B 2 18  ? 24.897 39.857  9.133  1.00 20.00 ? 18  ASP A H      1 
ATOM   1919 N N      . LEU B 2 19  ? 24.455 40.044  5.794  1.00 14.08 ? 19  LEU A N      1 
ATOM   1920 C CA     . LEU B 2 19  ? 23.936 39.889  4.446  1.00 10.80 ? 19  LEU A CA     1 
ATOM   1921 C C      . LEU B 2 19  ? 22.686 40.742  4.248  1.00 13.67 ? 19  LEU A C      1 
ATOM   1922 O O      . LEU B 2 19  ? 22.602 41.533  3.297  1.00 12.48 ? 19  LEU A O      1 
ATOM   1923 C CB     . LEU B 2 19  ? 23.609 38.427  4.185  1.00 6.09  ? 19  LEU A CB     1 
ATOM   1924 C CG     . LEU B 2 19  ? 24.702 37.585  3.529  1.00 4.34  ? 19  LEU A CG     1 
ATOM   1925 C CD1    . LEU B 2 19  ? 26.082 38.033  3.966  1.00 3.94  ? 19  LEU A CD1    1 
ATOM   1926 C CD2    . LEU B 2 19  ? 24.523 36.112  3.859  1.00 5.88  ? 19  LEU A CD2    1 
ATOM   1927 H H      . LEU B 2 19  ? 24.435 39.285  6.416  1.00 20.00 ? 19  LEU A H      1 
ATOM   1928 N N      . ALA B 2 20  ? 21.747 40.604  5.187  1.00 17.89 ? 20  ALA A N      1 
ATOM   1929 C CA     . ALA B 2 20  ? 20.463 41.311  5.162  1.00 20.82 ? 20  ALA A CA     1 
ATOM   1930 C C      . ALA B 2 20  ? 20.630 42.813  5.141  1.00 21.07 ? 20  ALA A C      1 
ATOM   1931 O O      . ALA B 2 20  ? 20.133 43.489  4.251  1.00 22.80 ? 20  ALA A O      1 
ATOM   1932 C CB     . ALA B 2 20  ? 19.598 40.898  6.375  1.00 20.13 ? 20  ALA A CB     1 
ATOM   1933 H H      . ALA B 2 20  ? 21.919 39.987  5.938  1.00 20.00 ? 20  ALA A H      1 
ATOM   1934 N N      . SER B 2 21  ? 21.342 43.328  6.127  1.00 20.88 ? 21  SER A N      1 
ATOM   1935 C CA     . SER B 2 21  ? 21.584 44.763  6.253  1.00 22.65 ? 21  SER A CA     1 
ATOM   1936 C C      . SER B 2 21  ? 22.309 45.314  5.028  1.00 23.98 ? 21  SER A C      1 
ATOM   1937 O O      . SER B 2 21  ? 22.455 46.524  4.875  1.00 23.46 ? 21  SER A O      1 
ATOM   1938 C CB     . SER B 2 21  ? 22.450 45.027  7.485  1.00 23.22 ? 21  SER A CB     1 
ATOM   1939 O OG     . SER B 2 21  ? 23.753 44.488  7.291  1.00 24.03 ? 21  SER A OG     1 
ATOM   1940 H H      . SER B 2 21  ? 21.723 42.720  6.780  1.00 20.00 ? 21  SER A H      1 
ATOM   1941 H HG     . SER B 2 21  ? 24.285 44.612  8.077  1.00 20.00 ? 21  SER A HG     1 
ATOM   1942 N N      . GLY B 2 22  ? 22.816 44.425  4.186  1.00 25.49 ? 22  GLY A N      1 
ATOM   1943 C CA     . GLY B 2 22  ? 23.538 44.875  3.017  1.00 25.24 ? 22  GLY A CA     1 
ATOM   1944 C C      . GLY B 2 22  ? 24.945 45.284  3.417  1.00 24.45 ? 22  GLY A C      1 
ATOM   1945 O O      . GLY B 2 22  ? 25.634 46.019  2.692  1.00 27.24 ? 22  GLY A O      1 
ATOM   1946 H H      . GLY B 2 22  ? 22.684 43.463  4.323  1.00 20.00 ? 22  GLY A H      1 
ATOM   1947 N N      . LYS B 2 23  ? 25.398 44.834  4.581  1.00 25.05 ? 23  LYS A N      1 
ATOM   1948 C CA     . LYS B 2 23  ? 26.750 45.186  4.968  1.00 24.59 ? 23  LYS A CA     1 
ATOM   1949 C C      . LYS B 2 23  ? 27.696 44.456  4.025  1.00 22.47 ? 23  LYS A C      1 
ATOM   1950 O O      . LYS B 2 23  ? 28.754 44.973  3.673  1.00 23.86 ? 23  LYS A O      1 
ATOM   1951 C CB     . LYS B 2 23  ? 27.052 44.828  6.423  1.00 28.35 ? 23  LYS A CB     1 
ATOM   1952 C CG     . LYS B 2 23  ? 28.443 45.286  6.831  1.00 31.52 ? 23  LYS A CG     1 
ATOM   1953 C CD     . LYS B 2 23  ? 28.711 45.179  8.320  1.00 33.69 ? 23  LYS A CD     1 
ATOM   1954 C CE     . LYS B 2 23  ? 30.146 45.620  8.617  1.00 34.49 ? 23  LYS A CE     1 
ATOM   1955 N NZ     . LYS B 2 23  ? 30.530 45.617  10.057 1.00 35.79 ? 23  LYS A NZ     1 
ATOM   1956 H H      . LYS B 2 23  ? 24.830 44.292  5.161  1.00 20.00 ? 23  LYS A H      1 
ATOM   1957 H HZ1    . LYS B 2 23  ? 30.216 44.712  10.507 1.00 20.00 ? 23  LYS A HZ1    1 
ATOM   1958 H HZ2    . LYS B 2 23  ? 31.577 45.649  10.146 1.00 20.00 ? 23  LYS A HZ2    1 
ATOM   1959 H HZ3    . LYS B 2 23  ? 30.110 46.406  10.550 1.00 20.00 ? 23  LYS A HZ3    1 
ATOM   1960 N N      . HIS B 2 24  ? 27.339 43.229  3.661  1.00 20.17 ? 24  HIS A N      1 
ATOM   1961 C CA     . HIS B 2 24  ? 28.157 42.444  2.741  1.00 17.78 ? 24  HIS A CA     1 
ATOM   1962 C C      . HIS B 2 24  ? 27.274 41.832  1.689  1.00 18.19 ? 24  HIS A C      1 
ATOM   1963 O O      . HIS B 2 24  ? 26.060 41.803  1.809  1.00 18.18 ? 24  HIS A O      1 
ATOM   1964 C CB     . HIS B 2 24  ? 28.866 41.305  3.458  1.00 15.45 ? 24  HIS A CB     1 
ATOM   1965 C CG     . HIS B 2 24  ? 29.867 41.754  4.467  1.00 11.59 ? 24  HIS A CG     1 
ATOM   1966 N ND1    . HIS B 2 24  ? 31.062 42.350  4.111  1.00 9.90  ? 24  HIS A ND1    1 
ATOM   1967 C CD2    . HIS B 2 24  ? 29.870 41.678  5.817  1.00 9.28  ? 24  HIS A CD2    1 
ATOM   1968 C CE1    . HIS B 2 24  ? 31.752 42.614  5.204  1.00 9.20  ? 24  HIS A CE1    1 
ATOM   1969 N NE2    . HIS B 2 24  ? 31.049 42.215  6.254  1.00 11.17 ? 24  HIS A NE2    1 
ATOM   1970 H H      . HIS B 2 24  ? 26.493 42.849  4.009  1.00 20.00 ? 24  HIS A H      1 
ATOM   1971 H HD1    . HIS B 2 24  ? 31.373 42.519  3.172  1.00 20.00 ? 24  HIS A HD1    1 
ATOM   1972 H HE2    . HIS B 2 24  ? 31.330 42.371  7.172  1.00 20.00 ? 24  HIS A HE2    1 
ATOM   1973 N N      . THR B 2 25  ? 27.899 41.267  0.680  1.00 17.24 ? 25  THR A N      1 
ATOM   1974 C CA     . THR B 2 25  ? 27.158 40.636  -0.380 1.00 17.09 ? 25  THR A CA     1 
ATOM   1975 C C      . THR B 2 25  ? 27.679 39.218  -0.455 1.00 18.51 ? 25  THR A C      1 
ATOM   1976 O O      . THR B 2 25  ? 26.907 38.287  -0.694 1.00 18.32 ? 25  THR A O      1 
ATOM   1977 C CB     . THR B 2 25  ? 27.342 41.393  -1.716 1.00 19.05 ? 25  THR A CB     1 
ATOM   1978 O OG1    . THR B 2 25  ? 28.731 41.472  -2.036 1.00 19.50 ? 25  THR A OG1    1 
ATOM   1979 C CG2    . THR B 2 25  ? 26.800 42.826  -1.607 1.00 19.58 ? 25  THR A CG2    1 
ATOM   1980 H H      . THR B 2 25  ? 28.865 41.284  0.639  1.00 20.00 ? 25  THR A H      1 
ATOM   1981 H HG1    . THR B 2 25  ? 28.837 41.934  -2.882 1.00 20.00 ? 25  THR A HG1    1 
ATOM   1982 N N      . THR B 2 26  ? 28.970 39.034  -0.178 1.00 17.15 ? 26  THR A N      1 
ATOM   1983 C CA     . THR B 2 26  ? 29.557 37.687  -0.192 1.00 17.44 ? 26  THR A CA     1 
ATOM   1984 C C      . THR B 2 26  ? 30.291 37.493  1.117  1.00 15.13 ? 26  THR A C      1 
ATOM   1985 O O      . THR B 2 26  ? 30.701 38.487  1.720  1.00 16.70 ? 26  THR A O      1 
ATOM   1986 C CB     . THR B 2 26  ? 30.593 37.512  -1.323 1.00 19.04 ? 26  THR A CB     1 
ATOM   1987 O OG1    . THR B 2 26  ? 30.084 38.049  -2.559 1.00 21.69 ? 26  THR A OG1    1 
ATOM   1988 C CG2    . THR B 2 26  ? 30.908 36.010  -1.525 1.00 20.19 ? 26  THR A CG2    1 
ATOM   1989 H H      . THR B 2 26  ? 29.540 39.784  0.029  1.00 20.00 ? 26  THR A H      1 
ATOM   1990 H HG1    . THR B 2 26  ? 30.738 37.925  -3.243 1.00 20.00 ? 26  THR A HG1    1 
ATOM   1991 N N      . VAL B 2 27  ? 30.418 36.252  1.597  1.00 10.04 ? 27  VAL A N      1 
ATOM   1992 C CA     . VAL B 2 27  ? 31.181 36.039  2.829  1.00 5.73  ? 27  VAL A CA     1 
ATOM   1993 C C      . VAL B 2 27  ? 32.511 35.383  2.490  1.00 4.41  ? 27  VAL A C      1 
ATOM   1994 O O      . VAL B 2 27  ? 32.580 34.484  1.648  1.00 7.90  ? 27  VAL A O      1 
ATOM   1995 C CB     . VAL B 2 27  ? 30.418 35.238  3.925  1.00 5.70  ? 27  VAL A CB     1 
ATOM   1996 C CG1    . VAL B 2 27  ? 28.923 35.475  3.817  1.00 6.60  ? 27  VAL A CG1    1 
ATOM   1997 C CG2    . VAL B 2 27  ? 30.730 33.794  3.857  1.00 4.89  ? 27  VAL A CG2    1 
ATOM   1998 H H      . VAL B 2 27  ? 29.999 35.487  1.131  1.00 20.00 ? 27  VAL A H      1 
ATOM   1999 N N      . HIS B 2 28  ? 33.581 35.883  3.089  1.00 2.20  ? 28  HIS A N      1 
ATOM   2000 C CA     . HIS B 2 28  ? 34.895 35.333  2.846  1.00 2.32  ? 28  HIS A CA     1 
ATOM   2001 C C      . HIS B 2 28  ? 35.650 35.083  4.156  1.00 2.00  ? 28  HIS A C      1 
ATOM   2002 O O      . HIS B 2 28  ? 36.141 36.019  4.810  1.00 2.00  ? 28  HIS A O      1 
ATOM   2003 C CB     . HIS B 2 28  ? 35.681 36.273  1.948  1.00 2.00  ? 28  HIS A CB     1 
ATOM   2004 C CG     . HIS B 2 28  ? 36.804 35.616  1.234  1.00 2.00  ? 28  HIS A CG     1 
ATOM   2005 N ND1    . HIS B 2 28  ? 37.274 36.072  0.016  1.00 3.48  ? 28  HIS A ND1    1 
ATOM   2006 C CD2    . HIS B 2 28  ? 37.565 34.542  1.541  1.00 2.64  ? 28  HIS A CD2    1 
ATOM   2007 C CE1    . HIS B 2 28  ? 38.276 35.316  -0.386 1.00 6.25  ? 28  HIS A CE1    1 
ATOM   2008 N NE2    . HIS B 2 28  ? 38.475 34.373  0.526  1.00 4.93  ? 28  HIS A NE2    1 
ATOM   2009 H H      . HIS B 2 28  ? 33.497 36.592  3.710  1.00 20.00 ? 28  HIS A H      1 
ATOM   2010 H HD1    . HIS B 2 28  ? 36.911 36.835  -0.489 1.00 20.00 ? 28  HIS A HD1    1 
ATOM   2011 H HE2    . HIS B 2 28  ? 39.173 33.702  0.484  1.00 20.00 ? 28  HIS A HE2    1 
ATOM   2012 N N      . THR B 2 29  ? 35.779 33.807  4.498  1.00 2.01  ? 29  THR A N      1 
ATOM   2013 C CA     . THR B 2 29  ? 36.447 33.395  5.713  1.00 2.01  ? 29  THR A CA     1 
ATOM   2014 C C      . THR B 2 29  ? 37.793 32.774  5.386  1.00 2.00  ? 29  THR A C      1 
ATOM   2015 O O      . THR B 2 29  ? 38.146 32.678  4.225  1.00 2.00  ? 29  THR A O      1 
ATOM   2016 C CB     . THR B 2 29  ? 35.616 32.360  6.370  1.00 2.00  ? 29  THR A CB     1 
ATOM   2017 O OG1    . THR B 2 29  ? 35.390 31.298  5.433  1.00 2.00  ? 29  THR A OG1    1 
ATOM   2018 C CG2    . THR B 2 29  ? 34.292 32.970  6.816  1.00 2.01  ? 29  THR A CG2    1 
ATOM   2019 H H      . THR B 2 29  ? 35.454 33.089  3.908  1.00 20.00 ? 29  THR A H      1 
ATOM   2020 H HG1    . THR B 2 29  ? 34.831 30.619  5.872  1.00 20.00 ? 29  THR A HG1    1 
ATOM   2021 N N      . ARG B 2 30  ? 38.548 32.347  6.398  1.00 2.00  ? 30  ARG A N      1 
ATOM   2022 C CA     . ARG B 2 30  ? 39.860 31.711  6.169  1.00 2.01  ? 30  ARG A CA     1 
ATOM   2023 C C      . ARG B 2 30  ? 40.230 30.815  7.331  1.00 2.00  ? 30  ARG A C      1 
ATOM   2024 O O      . ARG B 2 30  ? 39.701 30.989  8.422  1.00 2.01  ? 30  ARG A O      1 
ATOM   2025 C CB     . ARG B 2 30  ? 40.970 32.747  5.989  1.00 2.00  ? 30  ARG A CB     1 
ATOM   2026 C CG     . ARG B 2 30  ? 41.911 32.945  7.179  1.00 2.00  ? 30  ARG A CG     1 
ATOM   2027 C CD     . ARG B 2 30  ? 41.489 34.118  8.026  1.00 2.01  ? 30  ARG A CD     1 
ATOM   2028 N NE     . ARG B 2 30  ? 40.599 33.730  9.096  1.00 2.01  ? 30  ARG A NE     1 
ATOM   2029 C CZ     . ARG B 2 30  ? 40.942 33.730  10.382 1.00 2.00  ? 30  ARG A CZ     1 
ATOM   2030 N NH1    . ARG B 2 30  ? 42.162 34.046  10.755 1.00 2.01  ? 30  ARG A NH1    1 
ATOM   2031 N NH2    . ARG B 2 30  ? 40.064 33.370  11.303 1.00 2.54  ? 30  ARG A NH2    1 
ATOM   2032 H H      . ARG B 2 30  ? 38.253 32.509  7.330  1.00 20.00 ? 30  ARG A H      1 
ATOM   2033 H HE     . ARG B 2 30  ? 39.697 33.407  8.867  1.00 20.00 ? 30  ARG A HE     1 
ATOM   2034 H HH11   . ARG B 2 30  ? 42.826 34.334  10.082 1.00 20.00 ? 30  ARG A HH11   1 
ATOM   2035 H HH12   . ARG B 2 30  ? 42.385 34.061  11.737 1.00 20.00 ? 30  ARG A HH12   1 
ATOM   2036 H HH21   . ARG B 2 30  ? 39.150 33.047  11.042 1.00 20.00 ? 30  ARG A HH21   1 
ATOM   2037 H HH22   . ARG B 2 30  ? 40.330 33.340  12.273 1.00 20.00 ? 30  ARG A HH22   1 
ATOM   2038 N N      . PHE B 2 31  ? 41.061 29.818  7.087  1.00 2.01  ? 31  PHE A N      1 
ATOM   2039 C CA     . PHE B 2 31  ? 41.499 28.952  8.154  1.00 2.00  ? 31  PHE A CA     1 
ATOM   2040 C C      . PHE B 2 31  ? 42.974 29.266  8.151  1.00 2.01  ? 31  PHE A C      1 
ATOM   2041 O O      . PHE B 2 31  ? 43.615 29.074  7.137  1.00 2.01  ? 31  PHE A O      1 
ATOM   2042 C CB     . PHE B 2 31  ? 41.256 27.502  7.800  1.00 2.01  ? 31  PHE A CB     1 
ATOM   2043 C CG     . PHE B 2 31  ? 41.875 26.536  8.765  1.00 2.01  ? 31  PHE A CG     1 
ATOM   2044 C CD1    . PHE B 2 31  ? 41.625 26.642  10.133 1.00 2.01  ? 31  PHE A CD1    1 
ATOM   2045 C CD2    . PHE B 2 31  ? 42.725 25.550  8.322  1.00 2.01  ? 31  PHE A CD2    1 
ATOM   2046 C CE1    . PHE B 2 31  ? 42.199 25.806  11.027 1.00 2.01  ? 31  PHE A CE1    1 
ATOM   2047 C CE2    . PHE B 2 31  ? 43.304 24.711  9.214  1.00 2.01  ? 31  PHE A CE2    1 
ATOM   2048 C CZ     . PHE B 2 31  ? 43.035 24.844  10.573 1.00 2.01  ? 31  PHE A CZ     1 
ATOM   2049 H H      . PHE B 2 31  ? 41.436 29.697  6.192  1.00 20.00 ? 31  PHE A H      1 
ATOM   2050 N N      . PRO B 2 32  ? 43.568 29.654  9.290  1.00 2.01  ? 32  PRO A N      1 
ATOM   2051 C CA     . PRO B 2 32  ? 44.994 29.959  9.171  1.00 2.01  ? 32  PRO A CA     1 
ATOM   2052 C C      . PRO B 2 32  ? 45.906 29.278  10.176 1.00 2.00  ? 32  PRO A C      1 
ATOM   2053 O O      . PRO B 2 32  ? 46.437 29.927  11.064 1.00 2.01  ? 32  PRO A O      1 
ATOM   2054 C CB     . PRO B 2 32  ? 45.009 31.447  9.389  1.00 2.01  ? 32  PRO A CB     1 
ATOM   2055 C CG     . PRO B 2 32  ? 44.032 31.581  10.534 1.00 2.01  ? 32  PRO A CG     1 
ATOM   2056 C CD     . PRO B 2 32  ? 42.933 30.558  10.261 1.00 2.01  ? 32  PRO A CD     1 
ATOM   2057 N N      . PRO B 2 33  ? 46.235 28.013  9.948  1.00 2.00  ? 33  PRO A N      1 
ATOM   2058 C CA     . PRO B 2 33  ? 47.093 27.386  10.941 1.00 2.00  ? 33  PRO A CA     1 
ATOM   2059 C C      . PRO B 2 33  ? 48.530 27.722  10.702 1.00 2.01  ? 33  PRO A C      1 
ATOM   2060 O O      . PRO B 2 33  ? 48.905 27.925  9.564  1.00 2.00  ? 33  PRO A O      1 
ATOM   2061 C CB     . PRO B 2 33  ? 46.858 25.913  10.674 1.00 2.01  ? 33  PRO A CB     1 
ATOM   2062 C CG     . PRO B 2 33  ? 46.856 25.873  9.210  1.00 2.01  ? 33  PRO A CG     1 
ATOM   2063 C CD     . PRO B 2 33  ? 45.968 27.069  8.851  1.00 2.01  ? 33  PRO A CD     1 
ATOM   2064 N N      . GLU B 2 34  ? 49.332 27.773  11.764 1.00 2.01  ? 34  GLU A N      1 
ATOM   2065 C CA     . GLU B 2 34  ? 50.759 28.021  11.614 1.00 2.01  ? 34  GLU A CA     1 
ATOM   2066 C C      . GLU B 2 34  ? 51.293 26.636  11.299 1.00 2.00  ? 34  GLU A C      1 
ATOM   2067 O O      . GLU B 2 34  ? 50.785 25.653  11.811 1.00 2.45  ? 34  GLU A O      1 
ATOM   2068 C CB     . GLU B 2 34  ? 51.393 28.514  12.926 1.00 2.01  ? 34  GLU A CB     1 
ATOM   2069 C CG     . GLU B 2 34  ? 52.901 28.908  12.792 1.00 2.01  ? 34  GLU A CG     1 
ATOM   2070 C CD     . GLU B 2 34  ? 53.606 29.128  14.115 1.00 2.01  ? 34  GLU A CD     1 
ATOM   2071 O OE1    . GLU B 2 34  ? 53.015 28.965  15.188 1.00 2.66  ? 34  GLU A OE1    1 
ATOM   2072 O OE2    . GLU B 2 34  ? 54.797 29.452  14.100 1.00 2.01  ? 34  GLU A OE2    1 
ATOM   2073 H H      . GLU B 2 34  ? 48.960 27.628  12.653 1.00 20.00 ? 34  GLU A H      1 
ATOM   2074 N N      . PRO B 2 35  ? 52.333 26.541  10.478 1.00 2.01  ? 35  PRO A N      1 
ATOM   2075 C CA     . PRO B 2 35  ? 52.767 25.175  10.239 1.00 2.01  ? 35  PRO A CA     1 
ATOM   2076 C C      . PRO B 2 35  ? 53.864 24.754  11.218 1.00 2.00  ? 35  PRO A C      1 
ATOM   2077 O O      . PRO B 2 35  ? 55.048 24.641  10.845 1.00 2.00  ? 35  PRO A O      1 
ATOM   2078 C CB     . PRO B 2 35  ? 53.284 25.254  8.810  1.00 2.00  ? 35  PRO A CB     1 
ATOM   2079 C CG     . PRO B 2 35  ? 53.932 26.582  8.798  1.00 2.00  ? 35  PRO A CG     1 
ATOM   2080 C CD     . PRO B 2 35  ? 52.881 27.444  9.459  1.00 2.01  ? 35  PRO A CD     1 
ATOM   2081 N N      . ASN B 2 36  ? 53.476 24.510  12.466 1.00 2.00  ? 36  ASN A N      1 
ATOM   2082 C CA     . ASN B 2 36  ? 54.443 24.103  13.487 1.00 2.00  ? 36  ASN A CA     1 
ATOM   2083 C C      . ASN B 2 36  ? 53.997 22.821  14.179 1.00 2.00  ? 36  ASN A C      1 
ATOM   2084 O O      . ASN B 2 36  ? 54.399 22.530  15.319 1.00 2.00  ? 36  ASN A O      1 
ATOM   2085 C CB     . ASN B 2 36  ? 54.642 25.214  14.526 1.00 2.01  ? 36  ASN A CB     1 
ATOM   2086 C CG     . ASN B 2 36  ? 53.459 25.391  15.419 1.00 2.01  ? 36  ASN A CG     1 
ATOM   2087 O OD1    . ASN B 2 36  ? 52.319 25.397  14.957 1.00 2.00  ? 36  ASN A OD1    1 
ATOM   2088 N ND2    . ASN B 2 36  ? 53.706 25.522  16.715 1.00 2.01  ? 36  ASN A ND2    1 
ATOM   2089 H H      . ASN B 2 36  ? 52.535 24.652  12.734 1.00 20.00 ? 36  ASN A H      1 
ATOM   2090 H HD21   . ASN B 2 36  ? 52.917 25.632  17.306 1.00 20.00 ? 36  ASN A HD21   1 
ATOM   2091 H HD22   . ASN B 2 36  ? 54.614 25.450  17.055 1.00 20.00 ? 36  ASN A HD22   1 
ATOM   2092 N N      . GLY B 2 37  ? 53.218 22.018  13.472 1.00 2.00  ? 37  GLY A N      1 
ATOM   2093 C CA     . GLY B 2 37  ? 52.722 20.796  14.060 1.00 2.01  ? 37  GLY A CA     1 
ATOM   2094 C C      . GLY B 2 37  ? 51.593 20.302  13.207 1.00 2.00  ? 37  GLY A C      1 
ATOM   2095 O O      . GLY B 2 37  ? 51.198 21.012  12.294 1.00 2.00  ? 37  GLY A O      1 
ATOM   2096 H H      . GLY B 2 37  ? 52.956 22.246  12.569 1.00 20.00 ? 37  GLY A H      1 
ATOM   2097 N N      . TYR B 2 38  ? 51.139 19.072  13.431 1.00 2.01  ? 38  TYR A N      1 
ATOM   2098 C CA     . TYR B 2 38  ? 50.038 18.545  12.661 1.00 2.00  ? 38  TYR A CA     1 
ATOM   2099 C C      . TYR B 2 38  ? 48.736 19.082  13.237 1.00 2.01  ? 38  TYR A C      1 
ATOM   2100 O O      . TYR B 2 38  ? 48.675 19.480  14.391 1.00 2.01  ? 38  TYR A O      1 
ATOM   2101 C CB     . TYR B 2 38  ? 50.025 17.029  12.705 1.00 2.00  ? 38  TYR A CB     1 
ATOM   2102 C CG     . TYR B 2 38  ? 51.036 16.341  11.823 1.00 2.00  ? 38  TYR A CG     1 
ATOM   2103 C CD1    . TYR B 2 38  ? 52.340 16.800  11.732 1.00 2.01  ? 38  TYR A CD1    1 
ATOM   2104 C CD2    . TYR B 2 38  ? 50.674 15.208  11.086 1.00 2.01  ? 38  TYR A CD2    1 
ATOM   2105 C CE1    . TYR B 2 38  ? 53.259 16.161  10.939 1.00 2.01  ? 38  TYR A CE1    1 
ATOM   2106 C CE2    . TYR B 2 38  ? 51.585 14.563  10.294 1.00 2.00  ? 38  TYR A CE2    1 
ATOM   2107 C CZ     . TYR B 2 38  ? 52.883 15.046  10.227 1.00 2.01  ? 38  TYR A CZ     1 
ATOM   2108 O OH     . TYR B 2 38  ? 53.826 14.404  9.462  1.00 4.86  ? 38  TYR A OH     1 
ATOM   2109 H H      . TYR B 2 38  ? 51.487 18.550  14.178 1.00 20.00 ? 38  TYR A H      1 
ATOM   2110 H HH     . TYR B 2 38  ? 53.405 13.652  9.002  1.00 20.00 ? 38  TYR A HH     1 
ATOM   2111 N N      . LEU B 2 39  ? 47.695 19.083  12.419 1.00 2.01  ? 39  LEU A N      1 
ATOM   2112 C CA     . LEU B 2 39  ? 46.381 19.582  12.821 1.00 2.00  ? 39  LEU A CA     1 
ATOM   2113 C C      . LEU B 2 39  ? 45.782 18.598  13.771 1.00 2.01  ? 39  LEU A C      1 
ATOM   2114 O O      . LEU B 2 39  ? 46.151 17.436  13.730 1.00 2.61  ? 39  LEU A O      1 
ATOM   2115 C CB     . LEU B 2 39  ? 45.480 19.689  11.605 1.00 2.67  ? 39  LEU A CB     1 
ATOM   2116 C CG     . LEU B 2 39  ? 45.377 21.035  10.906 1.00 2.01  ? 39  LEU A CG     1 
ATOM   2117 C CD1    . LEU B 2 39  ? 46.731 21.654  10.715 1.00 2.01  ? 39  LEU A CD1    1 
ATOM   2118 C CD2    . LEU B 2 39  ? 44.659 20.856  9.591  1.00 2.01  ? 39  LEU A CD2    1 
ATOM   2119 H H      . LEU B 2 39  ? 47.816 18.745  11.500 1.00 20.00 ? 39  LEU A H      1 
ATOM   2120 N N      . HIS B 2 40  ? 44.890 19.047  14.645 1.00 2.01  ? 40  HIS A N      1 
ATOM   2121 C CA     . HIS B 2 40  ? 44.256 18.153  15.583 1.00 2.00  ? 40  HIS A CA     1 
ATOM   2122 C C      . HIS B 2 40  ? 42.757 18.362  15.633 1.00 2.00  ? 40  HIS A C      1 
ATOM   2123 O O      . HIS B 2 40  ? 42.252 19.336  15.088 1.00 2.00  ? 40  HIS A O      1 
ATOM   2124 C CB     . HIS B 2 40  ? 44.877 18.246  16.966 1.00 2.01  ? 40  HIS A CB     1 
ATOM   2125 C CG     . HIS B 2 40  ? 44.863 19.617  17.567 1.00 2.01  ? 40  HIS A CG     1 
ATOM   2126 N ND1    . HIS B 2 40  ? 43.716 20.363  17.695 1.00 2.01  ? 40  HIS A ND1    1 
ATOM   2127 C CD2    . HIS B 2 40  ? 45.854 20.349  18.135 1.00 2.00  ? 40  HIS A CD2    1 
ATOM   2128 C CE1    . HIS B 2 40  ? 43.998 21.497  18.314 1.00 6.01  ? 40  HIS A CE1    1 
ATOM   2129 N NE2    . HIS B 2 40  ? 45.290 21.512  18.590 1.00 2.00  ? 40  HIS A NE2    1 
ATOM   2130 H H      . HIS B 2 40  ? 44.603 19.947  14.591 1.00 20.00 ? 40  HIS A H      1 
ATOM   2131 H HD1    . HIS B 2 40  ? 42.831 20.098  17.426 1.00 20.00 ? 40  HIS A HD1    1 
ATOM   2132 H HE2    . HIS B 2 40  ? 45.795 22.250  19.052 1.00 20.00 ? 40  HIS A HE2    1 
ATOM   2133 N N      . ILE B 2 41  ? 42.059 17.451  16.303 1.00 2.33  ? 41  ILE A N      1 
ATOM   2134 C CA     . ILE B 2 41  ? 40.587 17.495  16.400 1.00 2.53  ? 41  ILE A CA     1 
ATOM   2135 C C      . ILE B 2 41  ? 40.072 18.901  16.775 1.00 3.29  ? 41  ILE A C      1 
ATOM   2136 O O      . ILE B 2 41  ? 39.037 19.352  16.301 1.00 4.06  ? 41  ILE A O      1 
ATOM   2137 C CB     . ILE B 2 41  ? 40.036 16.369  17.369 1.00 2.05  ? 41  ILE A CB     1 
ATOM   2138 C CG1    . ILE B 2 41  ? 38.508 16.373  17.428 1.00 2.00  ? 41  ILE A CG1    1 
ATOM   2139 C CG2    . ILE B 2 41  ? 40.627 16.516  18.758 1.00 2.01  ? 41  ILE A CG2    1 
ATOM   2140 C CD1    . ILE B 2 41  ? 37.901 15.836  16.201 1.00 2.00  ? 41  ILE A CD1    1 
ATOM   2141 H H      . ILE B 2 41  ? 42.541 16.727  16.779 1.00 20.00 ? 41  ILE A H      1 
ATOM   2142 N N      . GLY B 2 42  ? 40.868 19.635  17.539 1.00 6.41  ? 42  GLY A N      1 
ATOM   2143 C CA     . GLY B 2 42  ? 40.465 20.977  17.890 1.00 2.95  ? 42  GLY A CA     1 
ATOM   2144 C C      . GLY B 2 42  ? 40.423 21.773  16.610 1.00 2.74  ? 42  GLY A C      1 
ATOM   2145 O O      . GLY B 2 42  ? 39.403 22.401  16.325 1.00 2.01  ? 42  GLY A O      1 
ATOM   2146 H H      . GLY B 2 42  ? 41.668 19.248  17.927 1.00 20.00 ? 42  GLY A H      1 
ATOM   2147 N N      . HIS B 2 43  ? 41.486 21.686  15.807 1.00 2.00  ? 43  HIS A N      1 
ATOM   2148 C CA     . HIS B 2 43  ? 41.553 22.428  14.547 1.00 2.00  ? 43  HIS A CA     1 
ATOM   2149 C C      . HIS B 2 43  ? 40.390 22.087  13.664 1.00 2.01  ? 43  HIS A C      1 
ATOM   2150 O O      . HIS B 2 43  ? 39.808 22.958  13.025 1.00 2.00  ? 43  HIS A O      1 
ATOM   2151 C CB     . HIS B 2 43  ? 42.865 22.189  13.779 1.00 2.01  ? 43  HIS A CB     1 
ATOM   2152 C CG     . HIS B 2 43  ? 44.070 22.773  14.441 1.00 2.01  ? 43  HIS A CG     1 
ATOM   2153 N ND1    . HIS B 2 43  ? 45.099 21.999  14.918 1.00 2.01  ? 43  HIS A ND1    1 
ATOM   2154 C CD2    . HIS B 2 43  ? 44.387 24.053  14.758 1.00 2.01  ? 43  HIS A CD2    1 
ATOM   2155 C CE1    . HIS B 2 43  ? 45.996 22.770  15.508 1.00 2.01  ? 43  HIS A CE1    1 
ATOM   2156 N NE2    . HIS B 2 43  ? 45.581 24.022  15.424 1.00 2.01  ? 43  HIS A NE2    1 
ATOM   2157 H H      . HIS B 2 43  ? 42.238 21.182  16.074 1.00 20.00 ? 43  HIS A H      1 
ATOM   2158 H HD1    . HIS B 2 43  ? 45.216 21.072  14.827 1.00 20.00 ? 43  HIS A HD1    1 
ATOM   2159 H HE2    . HIS B 2 43  ? 46.070 24.795  15.812 1.00 20.00 ? 43  HIS A HE2    1 
ATOM   2160 N N      . ALA B 2 44  ? 39.960 20.841  13.739 1.00 2.01  ? 44  ALA A N      1 
ATOM   2161 C CA     . ALA B 2 44  ? 38.851 20.395  12.918 1.00 2.00  ? 44  ALA A CA     1 
ATOM   2162 C C      . ALA B 2 44  ? 37.583 21.187  13.180 1.00 2.01  ? 44  ALA A C      1 
ATOM   2163 O O      . ALA B 2 44  ? 36.760 21.350  12.281 1.00 2.00  ? 44  ALA A O      1 
ATOM   2164 C CB     . ALA B 2 44  ? 38.602 18.906  13.099 1.00 2.01  ? 44  ALA A CB     1 
ATOM   2165 H H      . ALA B 2 44  ? 40.392 20.221  14.337 1.00 20.00 ? 44  ALA A H      1 
ATOM   2166 N N      . LYS B 2 45  ? 37.430 21.689  14.400 1.00 2.01  ? 45  LYS A N      1 
ATOM   2167 C CA     . LYS B 2 45  ? 36.249 22.464  14.748 1.00 2.00  ? 45  LYS A CA     1 
ATOM   2168 C C      . LYS B 2 45  ? 36.309 23.779  14.010 1.00 3.96  ? 45  LYS A C      1 
ATOM   2169 O O      . LYS B 2 45  ? 35.312 24.254  13.492 1.00 3.50  ? 45  LYS A O      1 
ATOM   2170 C CB     . LYS B 2 45  ? 36.206 22.738  16.236 1.00 2.01  ? 45  LYS A CB     1 
ATOM   2171 C CG     . LYS B 2 45  ? 35.094 23.626  16.663 1.00 2.00  ? 45  LYS A CG     1 
ATOM   2172 C CD     . LYS B 2 45  ? 35.258 24.004  18.119 1.00 2.00  ? 45  LYS A CD     1 
ATOM   2173 C CE     . LYS B 2 45  ? 33.995 24.657  18.619 1.00 2.00  ? 45  LYS A CE     1 
ATOM   2174 N NZ     . LYS B 2 45  ? 34.158 25.277  19.949 1.00 2.09  ? 45  LYS A NZ     1 
ATOM   2175 H H      . LYS B 2 45  ? 38.135 21.559  15.076 1.00 20.00 ? 45  LYS A H      1 
ATOM   2176 H HZ1    . LYS B 2 45  ? 35.013 25.810  19.915 1.00 20.00 ? 45  LYS A HZ1    1 
ATOM   2177 H HZ2    . LYS B 2 45  ? 33.321 25.855  20.129 1.00 20.00 ? 45  LYS A HZ2    1 
ATOM   2178 H HZ3    . LYS B 2 45  ? 34.210 24.503  20.650 1.00 20.00 ? 45  LYS A HZ3    1 
ATOM   2179 N N      . SER B 2 46  ? 37.495 24.366  13.953 1.00 5.83  ? 46  SER A N      1 
ATOM   2180 C CA     . SER B 2 46  ? 37.669 25.626  13.271 1.00 7.95  ? 46  SER A CA     1 
ATOM   2181 C C      . SER B 2 46  ? 37.512 25.437  11.761 1.00 7.07  ? 46  SER A C      1 
ATOM   2182 O O      . SER B 2 46  ? 36.842 26.223  11.111 1.00 6.66  ? 46  SER A O      1 
ATOM   2183 C CB     . SER B 2 46  ? 39.025 26.200  13.657 1.00 8.17  ? 46  SER A CB     1 
ATOM   2184 O OG     . SER B 2 46  ? 39.602 26.875  12.570 1.00 14.46 ? 46  SER A OG     1 
ATOM   2185 H H      . SER B 2 46  ? 38.277 23.960  14.388 1.00 20.00 ? 46  SER A H      1 
ATOM   2186 H HG     . SER B 2 46  ? 40.469 27.241  12.811 1.00 20.00 ? 46  SER A HG     1 
ATOM   2187 N N      . ILE B 2 47  ? 38.076 24.362  11.224 1.00 3.54  ? 47  ILE A N      1 
ATOM   2188 C CA     . ILE B 2 47  ? 37.992 24.033  9.795  1.00 2.01  ? 47  ILE A CA     1 
ATOM   2189 C C      . ILE B 2 47  ? 36.528 23.882  9.366  1.00 2.00  ? 47  ILE A C      1 
ATOM   2190 O O      . ILE B 2 47  ? 36.080 24.493  8.392  1.00 2.00  ? 47  ILE A O      1 
ATOM   2191 C CB     . ILE B 2 47  ? 38.758 22.714  9.486  1.00 2.00  ? 47  ILE A CB     1 
ATOM   2192 C CG1    . ILE B 2 47  ? 40.266 22.978  9.375  1.00 2.01  ? 47  ILE A CG1    1 
ATOM   2193 C CG2    . ILE B 2 47  ? 38.263 22.096  8.226  1.00 2.01  ? 47  ILE A CG2    1 
ATOM   2194 C CD1    . ILE B 2 47  ? 41.109 21.743  9.085  1.00 2.00  ? 47  ILE A CD1    1 
ATOM   2195 H H      . ILE B 2 47  ? 38.539 23.738  11.827 1.00 20.00 ? 47  ILE A H      1 
ATOM   2196 N N      . CYS B 2 48  ? 35.771 23.084  10.103 1.00 2.00  ? 48  CYS A N      1 
ATOM   2197 C CA     . CYS B 2 48  ? 34.372 22.884  9.767  1.00 2.00  ? 48  CYS A CA     1 
ATOM   2198 C C      . CYS B 2 48  ? 33.617 24.185  9.837  1.00 2.00  ? 48  CYS A C      1 
ATOM   2199 O O      . CYS B 2 48  ? 32.706 24.383  9.058  1.00 2.01  ? 48  CYS A O      1 
ATOM   2200 C CB     . CYS B 2 48  ? 33.746 21.862  10.699 1.00 2.40  ? 48  CYS A CB     1 
ATOM   2201 S SG     . CYS B 2 48  ? 34.464 20.227  10.499 1.00 2.01  ? 48  CYS A SG     1 
ATOM   2202 H H      . CYS B 2 48  ? 36.136 22.642  10.914 1.00 20.00 ? 48  CYS A H      1 
ATOM   2203 N N      . LEU B 2 49  ? 34.001 25.082  10.744 1.00 2.01  ? 49  LEU A N      1 
ATOM   2204 C CA     . LEU B 2 49  ? 33.303 26.370  10.918 1.00 2.01  ? 49  LEU A CA     1 
ATOM   2205 C C      . LEU B 2 49  ? 33.592 27.283  9.745  1.00 2.00  ? 49  LEU A C      1 
ATOM   2206 O O      . LEU B 2 49  ? 32.673 27.768  9.084  1.00 2.00  ? 49  LEU A O      1 
ATOM   2207 C CB     . LEU B 2 49  ? 33.785 27.065  12.200 1.00 2.00  ? 49  LEU A CB     1 
ATOM   2208 C CG     . LEU B 2 49  ? 32.966 28.003  13.099 1.00 2.00  ? 49  LEU A CG     1 
ATOM   2209 C CD1    . LEU B 2 49  ? 33.922 29.006  13.709 1.00 2.00  ? 49  LEU A CD1    1 
ATOM   2210 C CD2    . LEU B 2 49  ? 31.910 28.751  12.326 1.00 2.00  ? 49  LEU A CD2    1 
ATOM   2211 H H      . LEU B 2 49  ? 34.758 24.888  11.336 1.00 20.00 ? 49  LEU A H      1 
ATOM   2212 N N      . ASN B 2 50  ? 34.878 27.489  9.480  1.00 2.00  ? 50  ASN A N      1 
ATOM   2213 C CA     . ASN B 2 50  ? 35.325 28.375  8.418  1.00 2.58  ? 50  ASN A CA     1 
ATOM   2214 C C      . ASN B 2 50  ? 34.975 27.879  7.011  1.00 2.00  ? 50  ASN A C      1 
ATOM   2215 O O      . ASN B 2 50  ? 34.367 28.618  6.219  1.00 2.01  ? 50  ASN A O      1 
ATOM   2216 C CB     . ASN B 2 50  ? 36.826 28.714  8.564  1.00 2.00  ? 50  ASN A CB     1 
ATOM   2217 C CG     . ASN B 2 50  ? 37.113 29.672  9.725  1.00 2.01  ? 50  ASN A CG     1 
ATOM   2218 O OD1    . ASN B 2 50  ? 36.846 30.868  9.638  1.00 2.01  ? 50  ASN A OD1    1 
ATOM   2219 N ND2    . ASN B 2 50  ? 37.681 29.154  10.802 1.00 2.02  ? 50  ASN A ND2    1 
ATOM   2220 H H      . ASN B 2 50  ? 35.552 27.036  10.016 1.00 20.00 ? 50  ASN A H      1 
ATOM   2221 H HD21   . ASN B 2 50  ? 37.860 29.755  11.566 1.00 20.00 ? 50  ASN A HD21   1 
ATOM   2222 H HD22   . ASN B 2 50  ? 37.897 28.194  10.841 1.00 20.00 ? 50  ASN A HD22   1 
ATOM   2223 N N      . PHE B 2 51  ? 35.290 26.626  6.705  1.00 2.01  ? 51  PHE A N      1 
ATOM   2224 C CA     . PHE B 2 51  ? 34.963 26.108  5.385  1.00 2.00  ? 51  PHE A CA     1 
ATOM   2225 C C      . PHE B 2 51  ? 33.477 25.835  5.259  1.00 3.50  ? 51  PHE A C      1 
ATOM   2226 O O      . PHE B 2 51  ? 32.912 25.984  4.169  1.00 6.00  ? 51  PHE A O      1 
ATOM   2227 C CB     . PHE B 2 51  ? 35.747 24.857  5.025  1.00 2.01  ? 51  PHE A CB     1 
ATOM   2228 C CG     . PHE B 2 51  ? 37.216 25.084  4.863  1.00 2.00  ? 51  PHE A CG     1 
ATOM   2229 C CD1    . PHE B 2 51  ? 38.061 25.019  5.955  1.00 2.01  ? 51  PHE A CD1    1 
ATOM   2230 C CD2    . PHE B 2 51  ? 37.767 25.294  3.613  1.00 2.01  ? 51  PHE A CD2    1 
ATOM   2231 C CE1    . PHE B 2 51  ? 39.426 25.145  5.806  1.00 2.01  ? 51  PHE A CE1    1 
ATOM   2232 C CE2    . PHE B 2 51  ? 39.142 25.422  3.454  1.00 2.01  ? 51  PHE A CE2    1 
ATOM   2233 C CZ     . PHE B 2 51  ? 39.974 25.345  4.551  1.00 2.01  ? 51  PHE A CZ     1 
ATOM   2234 H H      . PHE B 2 51  ? 35.773 26.065  7.340  1.00 20.00 ? 51  PHE A H      1 
ATOM   2235 N N      . GLY B 2 52  ? 32.823 25.484  6.357  1.00 2.00  ? 52  GLY A N      1 
ATOM   2236 C CA     . GLY B 2 52  ? 31.399 25.198  6.287  1.00 2.00  ? 52  GLY A CA     1 
ATOM   2237 C C      . GLY B 2 52  ? 30.547 26.409  5.921  1.00 3.70  ? 52  GLY A C      1 
ATOM   2238 O O      . GLY B 2 52  ? 29.647 26.338  5.070  1.00 4.80  ? 52  GLY A O      1 
ATOM   2239 H H      . GLY B 2 52  ? 33.293 25.434  7.209  1.00 20.00 ? 52  GLY A H      1 
ATOM   2240 N N      . ILE B 2 53  ? 30.824 27.534  6.576  1.00 2.53  ? 53  ILE A N      1 
ATOM   2241 C CA     . ILE B 2 53  ? 30.087 28.771  6.336  1.00 2.00  ? 53  ILE A CA     1 
ATOM   2242 C C      . ILE B 2 53  ? 30.241 29.172  4.871  1.00 2.00  ? 53  ILE A C      1 
ATOM   2243 O O      . ILE B 2 53  ? 29.278 29.615  4.252  1.00 2.01  ? 53  ILE A O      1 
ATOM   2244 C CB     . ILE B 2 53  ? 30.626 29.908  7.228  1.00 2.00  ? 53  ILE A CB     1 
ATOM   2245 C CG1    . ILE B 2 53  ? 30.361 29.589  8.686  1.00 2.00  ? 53  ILE A CG1    1 
ATOM   2246 C CG2    . ILE B 2 53  ? 30.014 31.235  6.847  1.00 2.00  ? 53  ILE A CG2    1 
ATOM   2247 C CD1    . ILE B 2 53  ? 30.733 30.710  9.607  1.00 2.00  ? 53  ILE A CD1    1 
ATOM   2248 H H      . ILE B 2 53  ? 31.558 27.533  7.237  1.00 20.00 ? 53  ILE A H      1 
ATOM   2249 N N      . ALA B 2 54  ? 31.452 29.015  4.341  1.00 2.00  ? 54  ALA A N      1 
ATOM   2250 C CA     . ALA B 2 54  ? 31.732 29.369  2.969  1.00 3.02  ? 54  ALA A CA     1 
ATOM   2251 C C      . ALA B 2 54  ? 30.824 28.608  2.060  1.00 2.15  ? 54  ALA A C      1 
ATOM   2252 O O      . ALA B 2 54  ? 30.012 29.207  1.394  1.00 3.61  ? 54  ALA A O      1 
ATOM   2253 C CB     . ALA B 2 54  ? 33.152 29.081  2.608  1.00 8.27  ? 54  ALA A CB     1 
ATOM   2254 H H      . ALA B 2 54  ? 32.195 28.676  4.893  1.00 20.00 ? 54  ALA A H      1 
ATOM   2255 N N      . GLN B 2 55  ? 30.887 27.286  2.063  1.00 2.80  ? 55  GLN A N      1 
ATOM   2256 C CA     . GLN B 2 55  ? 30.009 26.554  1.167  1.00 8.79  ? 55  GLN A CA     1 
ATOM   2257 C C      . GLN B 2 55  ? 28.540 26.746  1.479  1.00 8.02  ? 55  GLN A C      1 
ATOM   2258 O O      . GLN B 2 55  ? 27.737 26.740  0.577  1.00 6.39  ? 55  GLN A O      1 
ATOM   2259 C CB     . GLN B 2 55  ? 30.361 25.066  1.100  1.00 15.14 ? 55  GLN A CB     1 
ATOM   2260 C CG     . GLN B 2 55  ? 30.143 24.288  2.376  1.00 21.51 ? 55  GLN A CG     1 
ATOM   2261 C CD     . GLN B 2 55  ? 30.758 22.887  2.307  1.00 26.05 ? 55  GLN A CD     1 
ATOM   2262 O OE1    . GLN B 2 55  ? 30.218 21.924  2.883  1.00 28.23 ? 55  GLN A OE1    1 
ATOM   2263 N NE2    . GLN B 2 55  ? 31.903 22.773  1.626  1.00 28.26 ? 55  GLN A NE2    1 
ATOM   2264 H H      . GLN B 2 55  ? 31.518 26.826  2.652  1.00 20.00 ? 55  GLN A H      1 
ATOM   2265 H HE21   . GLN B 2 55  ? 32.301 21.883  1.618  1.00 20.00 ? 55  GLN A HE21   1 
ATOM   2266 H HE22   . GLN B 2 55  ? 32.294 23.562  1.230  1.00 20.00 ? 55  GLN A HE22   1 
ATOM   2267 N N      . ASP B 2 56  ? 28.179 26.969  2.731  1.00 7.31  ? 56  ASP A N      1 
ATOM   2268 C CA     . ASP B 2 56  ? 26.770 27.162  3.032  1.00 6.68  ? 56  ASP A CA     1 
ATOM   2269 C C      . ASP B 2 56  ? 26.265 28.459  2.432  1.00 4.83  ? 56  ASP A C      1 
ATOM   2270 O O      . ASP B 2 56  ? 25.174 28.509  1.883  1.00 6.61  ? 56  ASP A O      1 
ATOM   2271 C CB     . ASP B 2 56  ? 26.498 27.168  4.546  1.00 10.65 ? 56  ASP A CB     1 
ATOM   2272 C CG     . ASP B 2 56  ? 26.577 25.776  5.177  1.00 13.15 ? 56  ASP A CG     1 
ATOM   2273 O OD1    . ASP B 2 56  ? 26.126 24.774  4.569  1.00 16.51 ? 56  ASP A OD1    1 
ATOM   2274 O OD2    . ASP B 2 56  ? 27.099 25.684  6.306  1.00 13.23 ? 56  ASP A OD2    1 
ATOM   2275 H H      . ASP B 2 56  ? 28.847 27.003  3.437  1.00 20.00 ? 56  ASP A H      1 
ATOM   2276 N N      . TYR B 2 57  ? 27.053 29.512  2.531  1.00 2.00  ? 57  TYR A N      1 
ATOM   2277 C CA     . TYR B 2 57  ? 26.631 30.788  1.995  1.00 2.01  ? 57  TYR A CA     1 
ATOM   2278 C C      . TYR B 2 57  ? 27.147 31.025  0.602  1.00 2.00  ? 57  TYR A C      1 
ATOM   2279 O O      . TYR B 2 57  ? 27.078 32.147  0.105  1.00 2.00  ? 57  TYR A O      1 
ATOM   2280 C CB     . TYR B 2 57  ? 27.094 31.922  2.893  1.00 2.01  ? 57  TYR A CB     1 
ATOM   2281 C CG     . TYR B 2 57  ? 26.423 31.938  4.240  1.00 4.61  ? 57  TYR A CG     1 
ATOM   2282 C CD1    . TYR B 2 57  ? 26.744 30.994  5.205  1.00 2.04  ? 57  TYR A CD1    1 
ATOM   2283 C CD2    . TYR B 2 57  ? 25.450 32.888  4.546  1.00 2.00  ? 57  TYR A CD2    1 
ATOM   2284 C CE1    . TYR B 2 57  ? 26.110 30.993  6.440  1.00 2.01  ? 57  TYR A CE1    1 
ATOM   2285 C CE2    . TYR B 2 57  ? 24.821 32.896  5.764  1.00 2.00  ? 57  TYR A CE2    1 
ATOM   2286 C CZ     . TYR B 2 57  ? 25.147 31.952  6.709  1.00 2.01  ? 57  TYR A CZ     1 
ATOM   2287 O OH     . TYR B 2 57  ? 24.503 31.951  7.922  1.00 3.21  ? 57  TYR A OH     1 
ATOM   2288 H H      . TYR B 2 57  ? 27.937 29.422  2.933  1.00 20.00 ? 57  TYR A H      1 
ATOM   2289 H HH     . TYR B 2 57  ? 23.822 32.585  7.953  1.00 20.00 ? 57  TYR A HH     1 
ATOM   2290 N N      . LYS B 2 58  ? 27.634 29.974  -0.047 1.00 6.56  ? 58  LYS A N      1 
ATOM   2291 C CA     . LYS B 2 58  ? 28.224 30.101  -1.375 1.00 7.15  ? 58  LYS A CA     1 
ATOM   2292 C C      . LYS B 2 58  ? 29.236 31.250  -1.306 1.00 2.43  ? 58  LYS A C      1 
ATOM   2293 O O      . LYS B 2 58  ? 29.018 32.302  -1.892 1.00 2.00  ? 58  LYS A O      1 
ATOM   2294 C CB     . LYS B 2 58  ? 27.148 30.390  -2.409 1.00 14.12 ? 58  LYS A CB     1 
ATOM   2295 C CG     . LYS B 2 58  ? 26.184 29.237  -2.672 1.00 22.30 ? 58  LYS A CG     1 
ATOM   2296 C CD     . LYS B 2 58  ? 26.666 28.383  -3.843 1.00 30.33 ? 58  LYS A CD     1 
ATOM   2297 C CE     . LYS B 2 58  ? 25.774 27.153  -4.098 1.00 36.65 ? 58  LYS A CE     1 
ATOM   2298 N NZ     . LYS B 2 58  ? 26.190 26.365  -5.325 1.00 37.47 ? 58  LYS A NZ     1 
ATOM   2299 H H      . LYS B 2 58  ? 27.665 29.108  0.402  1.00 20.00 ? 58  LYS A H      1 
ATOM   2300 H HZ1    . LYS B 2 58  ? 27.225 26.221  -5.319 1.00 20.00 ? 58  LYS A HZ1    1 
ATOM   2301 H HZ2    . LYS B 2 58  ? 25.728 25.425  -5.314 1.00 20.00 ? 58  LYS A HZ2    1 
ATOM   2302 H HZ3    . LYS B 2 58  ? 25.917 26.869  -6.186 1.00 20.00 ? 58  LYS A HZ3    1 
ATOM   2303 N N      . GLY B 2 59  ? 30.285 31.072  -0.509 1.00 2.00  ? 59  GLY A N      1 
ATOM   2304 C CA     . GLY B 2 59  ? 31.311 32.090  -0.350 1.00 2.01  ? 59  GLY A CA     1 
ATOM   2305 C C      . GLY B 2 59  ? 32.681 31.467  -0.500 1.00 2.00  ? 59  GLY A C      1 
ATOM   2306 O O      . GLY B 2 59  ? 32.747 30.325  -0.920 1.00 2.39  ? 59  GLY A O      1 
ATOM   2307 H H      . GLY B 2 59  ? 30.377 30.244  -0.034 1.00 20.00 ? 59  GLY A H      1 
ATOM   2308 N N      . GLN B 2 60  ? 33.754 32.186  -0.177 1.00 2.00  ? 60  GLN A N      1 
ATOM   2309 C CA     . GLN B 2 60  ? 35.101 31.632  -0.296 1.00 6.84  ? 60  GLN A CA     1 
ATOM   2310 C C      . GLN B 2 60  ? 35.744 31.474  1.071  1.00 6.21  ? 60  GLN A C      1 
ATOM   2311 O O      . GLN B 2 60  ? 35.425 32.222  1.998  1.00 2.00  ? 60  GLN A O      1 
ATOM   2312 C CB     . GLN B 2 60  ? 36.024 32.549  -1.110 1.00 13.34 ? 60  GLN A CB     1 
ATOM   2313 C CG     . GLN B 2 60  ? 35.540 32.930  -2.501 1.00 21.86 ? 60  GLN A CG     1 
ATOM   2314 C CD     . GLN B 2 60  ? 35.338 31.740  -3.425 1.00 26.90 ? 60  GLN A CD     1 
ATOM   2315 O OE1    . GLN B 2 60  ? 34.855 31.906  -4.549 1.00 30.26 ? 60  GLN A OE1    1 
ATOM   2316 N NE2    . GLN B 2 60  ? 35.724 30.540  -2.972 1.00 28.95 ? 60  GLN A NE2    1 
ATOM   2317 H H      . GLN B 2 60  ? 33.635 33.092  0.167  1.00 20.00 ? 60  GLN A H      1 
ATOM   2318 H HE21   . GLN B 2 60  ? 35.574 29.749  -3.574 1.00 20.00 ? 60  GLN A HE21   1 
ATOM   2319 H HE22   . GLN B 2 60  ? 36.146 30.409  -2.128 1.00 20.00 ? 60  GLN A HE22   1 
ATOM   2320 N N      . CYS B 2 61  ? 36.700 30.561  1.167  1.00 2.01  ? 61  CYS A N      1 
ATOM   2321 C CA     . CYS B 2 61  ? 37.429 30.355  2.401  1.00 2.00  ? 61  CYS A CA     1 
ATOM   2322 C C      . CYS B 2 61  ? 38.874 30.045  2.010  1.00 2.00  ? 61  CYS A C      1 
ATOM   2323 O O      . CYS B 2 61  ? 39.129 29.086  1.291  1.00 3.19  ? 61  CYS A O      1 
ATOM   2324 C CB     . CYS B 2 61  ? 36.830 29.204  3.192  1.00 6.28  ? 61  CYS A CB     1 
ATOM   2325 S SG     . CYS B 2 61  ? 37.685 28.899  4.752  1.00 7.66  ? 61  CYS A SG     1 
ATOM   2326 H H      . CYS B 2 61  ? 36.971 30.050  0.388  1.00 20.00 ? 61  CYS A H      1 
ATOM   2327 N N      . ASN B 2 62  ? 39.819 30.879  2.413  1.00 2.01  ? 62  ASN A N      1 
ATOM   2328 C CA     . ASN B 2 62  ? 41.218 30.652  2.038  1.00 2.00  ? 62  ASN A CA     1 
ATOM   2329 C C      . ASN B 2 62  ? 41.946 29.754  3.006  1.00 2.00  ? 62  ASN A C      1 
ATOM   2330 O O      . ASN B 2 62  ? 41.580 29.688  4.168  1.00 2.00  ? 62  ASN A O      1 
ATOM   2331 C CB     . ASN B 2 62  ? 41.982 31.970  1.977  1.00 2.00  ? 62  ASN A CB     1 
ATOM   2332 C CG     . ASN B 2 62  ? 41.392 32.944  0.987  1.00 2.01  ? 62  ASN A CG     1 
ATOM   2333 O OD1    . ASN B 2 62  ? 40.467 32.619  0.232  1.00 2.00  ? 62  ASN A OD1    1 
ATOM   2334 N ND2    . ASN B 2 62  ? 41.888 34.163  1.007  1.00 2.01  ? 62  ASN A ND2    1 
ATOM   2335 H H      . ASN B 2 62  ? 39.585 31.620  2.977  1.00 20.00 ? 62  ASN A H      1 
ATOM   2336 H HD21   . ASN B 2 62  ? 41.509 34.775  0.354  1.00 20.00 ? 62  ASN A HD21   1 
ATOM   2337 H HD22   . ASN B 2 62  ? 42.567 34.356  1.623  1.00 20.00 ? 62  ASN A HD22   1 
ATOM   2338 N N      . LEU B 2 63  ? 42.964 29.056  2.533  1.00 2.02  ? 63  LEU A N      1 
ATOM   2339 C CA     . LEU B 2 63  ? 43.778 28.261  3.431  1.00 2.01  ? 63  LEU A CA     1 
ATOM   2340 C C      . LEU B 2 63  ? 44.987 29.156  3.460  1.00 2.00  ? 63  LEU A C      1 
ATOM   2341 O O      . LEU B 2 63  ? 45.553 29.436  2.400  1.00 2.00  ? 63  LEU A O      1 
ATOM   2342 C CB     . LEU B 2 63  ? 44.183 26.916  2.832  1.00 2.01  ? 63  LEU A CB     1 
ATOM   2343 C CG     . LEU B 2 63  ? 44.954 26.070  3.838  1.00 2.01  ? 63  LEU A CG     1 
ATOM   2344 C CD1    . LEU B 2 63  ? 44.073 25.576  4.943  1.00 2.01  ? 63  LEU A CD1    1 
ATOM   2345 C CD2    . LEU B 2 63  ? 45.553 24.918  3.131  1.00 2.01  ? 63  LEU A CD2    1 
ATOM   2346 H H      . LEU B 2 63  ? 43.171 29.067  1.568  1.00 20.00 ? 63  LEU A H      1 
ATOM   2347 N N      . ARG B 2 64  ? 45.333 29.677  4.631  1.00 2.01  ? 64  ARG A N      1 
ATOM   2348 C CA     . ARG B 2 64  ? 46.476 30.558  4.733  1.00 2.01  ? 64  ARG A CA     1 
ATOM   2349 C C      . ARG B 2 64  ? 47.433 30.090  5.788  1.00 2.01  ? 64  ARG A C      1 
ATOM   2350 O O      . ARG B 2 64  ? 47.088 29.986  6.939  1.00 2.00  ? 64  ARG A O      1 
ATOM   2351 C CB     . ARG B 2 64  ? 46.022 31.969  5.069  1.00 2.01  ? 64  ARG A CB     1 
ATOM   2352 C CG     . ARG B 2 64  ? 47.177 32.919  5.136  1.00 2.01  ? 64  ARG A CG     1 
ATOM   2353 C CD     . ARG B 2 64  ? 46.737 34.344  5.122  1.00 2.00  ? 64  ARG A CD     1 
ATOM   2354 N NE     . ARG B 2 64  ? 46.242 34.748  6.418  1.00 2.00  ? 64  ARG A NE     1 
ATOM   2355 C CZ     . ARG B 2 64  ? 45.024 35.225  6.650  1.00 2.01  ? 64  ARG A CZ     1 
ATOM   2356 N NH1    . ARG B 2 64  ? 44.160 35.378  5.655  1.00 2.01  ? 64  ARG A NH1    1 
ATOM   2357 N NH2    . ARG B 2 64  ? 44.686 35.553  7.894  1.00 2.01  ? 64  ARG A NH2    1 
ATOM   2358 H H      . ARG B 2 64  ? 44.774 29.480  5.422  1.00 20.00 ? 64  ARG A H      1 
ATOM   2359 H HE     . ARG B 2 64  ? 46.838 34.625  7.168  1.00 20.00 ? 64  ARG A HE     1 
ATOM   2360 H HH11   . ARG B 2 64  ? 44.416 35.162  4.728  1.00 20.00 ? 64  ARG A HH11   1 
ATOM   2361 H HH12   . ARG B 2 64  ? 43.248 35.759  5.864  1.00 20.00 ? 64  ARG A HH12   1 
ATOM   2362 H HH21   . ARG B 2 64  ? 45.359 35.391  8.635  1.00 20.00 ? 64  ARG A HH21   1 
ATOM   2363 H HH22   . ARG B 2 64  ? 43.788 35.889  8.107  1.00 20.00 ? 64  ARG A HH22   1 
ATOM   2364 N N      . PHE B 2 65  ? 48.659 29.815  5.416  1.00 2.01  ? 65  PHE A N      1 
ATOM   2365 C CA     . PHE B 2 65  ? 49.602 29.360  6.402  1.00 2.01  ? 65  PHE A CA     1 
ATOM   2366 C C      . PHE B 2 65  ? 50.179 30.557  7.131  1.00 2.01  ? 65  PHE A C      1 
ATOM   2367 O O      . PHE B 2 65  ? 50.927 31.320  6.538  1.00 2.00  ? 65  PHE A O      1 
ATOM   2368 C CB     . PHE B 2 65  ? 50.697 28.521  5.734  1.00 2.01  ? 65  PHE A CB     1 
ATOM   2369 C CG     . PHE B 2 65  ? 50.253 27.130  5.355  1.00 2.00  ? 65  PHE A CG     1 
ATOM   2370 C CD1    . PHE B 2 65  ? 50.157 26.138  6.314  1.00 2.01  ? 65  PHE A CD1    1 
ATOM   2371 C CD2    . PHE B 2 65  ? 49.874 26.831  4.053  1.00 2.01  ? 65  PHE A CD2    1 
ATOM   2372 C CE1    . PHE B 2 65  ? 49.691 24.896  5.993  1.00 2.01  ? 65  PHE A CE1    1 
ATOM   2373 C CE2    . PHE B 2 65  ? 49.397 25.568  3.728  1.00 2.01  ? 65  PHE A CE2    1 
ATOM   2374 C CZ     . PHE B 2 65  ? 49.308 24.609  4.700  1.00 2.01  ? 65  PHE A CZ     1 
ATOM   2375 H H      . PHE B 2 65  ? 48.907 29.877  4.486  1.00 20.00 ? 65  PHE A H      1 
ATOM   2376 N N      . ASP B 2 66  ? 49.824 30.757  8.393  1.00 2.01  ? 66  ASP A N      1 
ATOM   2377 C CA     . ASP B 2 66  ? 50.389 31.874  9.142  1.00 2.01  ? 66  ASP A CA     1 
ATOM   2378 C C      . ASP B 2 66  ? 51.845 31.565  9.486  1.00 2.00  ? 66  ASP A C      1 
ATOM   2379 O O      . ASP B 2 66  ? 52.147 31.161  10.607 1.00 2.01  ? 66  ASP A O      1 
ATOM   2380 C CB     . ASP B 2 66  ? 49.621 32.054  10.433 1.00 2.00  ? 66  ASP A CB     1 
ATOM   2381 C CG     . ASP B 2 66  ? 49.193 33.475  10.649 1.00 2.00  ? 66  ASP A CG     1 
ATOM   2382 O OD1    . ASP B 2 66  ? 49.727 34.353  9.939  1.00 2.01  ? 66  ASP A OD1    1 
ATOM   2383 O OD2    . ASP B 2 66  ? 48.306 33.707  11.511 1.00 2.00  ? 66  ASP A OD2    1 
ATOM   2384 H H      . ASP B 2 66  ? 49.229 30.103  8.847  1.00 20.00 ? 66  ASP A H      1 
ATOM   2385 N N      . ASP B 2 67  ? 52.757 31.782  8.548  1.00 2.01  ? 67  ASP A N      1 
ATOM   2386 C CA     . ASP B 2 67  ? 54.167 31.460  8.757  1.00 2.01  ? 67  ASP A CA     1 
ATOM   2387 C C      . ASP B 2 67  ? 55.032 32.636  9.106  1.00 2.01  ? 67  ASP A C      1 
ATOM   2388 O O      . ASP B 2 67  ? 55.941 32.985  8.366  1.00 2.01  ? 67  ASP A O      1 
ATOM   2389 C CB     . ASP B 2 67  ? 54.727 30.780  7.501  1.00 2.01  ? 67  ASP A CB     1 
ATOM   2390 C CG     . ASP B 2 67  ? 54.419 31.556  6.223  1.00 2.01  ? 67  ASP A CG     1 
ATOM   2391 O OD1    . ASP B 2 67  ? 53.656 32.535  6.266  1.00 2.01  ? 67  ASP A OD1    1 
ATOM   2392 O OD2    . ASP B 2 67  ? 54.940 31.173  5.169  1.00 2.01  ? 67  ASP A OD2    1 
ATOM   2393 H H      . ASP B 2 67  ? 52.424 32.102  7.704  1.00 20.00 ? 67  ASP A H      1 
ATOM   2394 N N      . THR B 2 68  ? 54.785 33.214  10.260 1.00 2.01  ? 68  THR A N      1 
ATOM   2395 C CA     . THR B 2 68  ? 55.531 34.371  10.708 1.00 2.00  ? 68  THR A CA     1 
ATOM   2396 C C      . THR B 2 68  ? 56.720 34.073  11.625 1.00 5.13  ? 68  THR A C      1 
ATOM   2397 O O      . THR B 2 68  ? 57.601 34.911  11.799 1.00 5.83  ? 68  THR A O      1 
ATOM   2398 C CB     . THR B 2 68  ? 54.591 35.305  11.419 1.00 2.00  ? 68  THR A CB     1 
ATOM   2399 O OG1    . THR B 2 68  ? 53.776 34.539  12.307 1.00 2.01  ? 68  THR A OG1    1 
ATOM   2400 C CG2    . THR B 2 68  ? 53.691 36.019  10.383 1.00 2.01  ? 68  THR A CG2    1 
ATOM   2401 H H      . THR B 2 68  ? 54.058 32.861  10.840 1.00 20.00 ? 68  THR A H      1 
ATOM   2402 H HG1    . THR B 2 68  ? 53.219 35.199  12.782 1.00 20.00 ? 68  THR A HG1    1 
ATOM   2403 N N      . ASN B 2 69  ? 56.779 32.867  12.180 1.00 4.90  ? 69  ASN A N      1 
ATOM   2404 C CA     . ASN B 2 69  ? 57.874 32.504  13.089 1.00 5.62  ? 69  ASN A CA     1 
ATOM   2405 C C      . ASN B 2 69  ? 58.637 31.313  12.500 1.00 6.08  ? 69  ASN A C      1 
ATOM   2406 O O      . ASN B 2 69  ? 58.302 30.151  12.765 1.00 4.94  ? 69  ASN A O      1 
ATOM   2407 C CB     . ASN B 2 69  ? 57.307 32.153  14.477 1.00 6.34  ? 69  ASN A CB     1 
ATOM   2408 C CG     . ASN B 2 69  ? 58.368 32.169  15.568 1.00 9.84  ? 69  ASN A CG     1 
ATOM   2409 O OD1    . ASN B 2 69  ? 59.577 32.139  15.295 1.00 9.74  ? 69  ASN A OD1    1 
ATOM   2410 N ND2    . ASN B 2 69  ? 57.913 32.202  16.824 1.00 6.97  ? 69  ASN A ND2    1 
ATOM   2411 H H      . ASN B 2 69  ? 56.062 32.231  12.007 1.00 20.00 ? 69  ASN A H      1 
ATOM   2412 H HD21   . ASN B 2 69  ? 58.575 32.190  17.544 1.00 20.00 ? 69  ASN A HD21   1 
ATOM   2413 H HD22   . ASN B 2 69  ? 56.939 32.209  16.998 1.00 20.00 ? 69  ASN A HD22   1 
ATOM   2414 N N      . PRO B 2 70  ? 59.680 31.599  11.714 1.00 5.68  ? 70  PRO A N      1 
ATOM   2415 C CA     . PRO B 2 70  ? 60.506 30.580  11.070 1.00 7.11  ? 70  PRO A CA     1 
ATOM   2416 C C      . PRO B 2 70  ? 61.191 29.534  11.939 1.00 8.33  ? 70  PRO A C      1 
ATOM   2417 O O      . PRO B 2 70  ? 61.439 28.426  11.472 1.00 9.92  ? 70  PRO A O      1 
ATOM   2418 C CB     . PRO B 2 70  ? 61.537 31.413  10.318 1.00 5.37  ? 70  PRO A CB     1 
ATOM   2419 C CG     . PRO B 2 70  ? 61.728 32.549  11.193 1.00 7.57  ? 70  PRO A CG     1 
ATOM   2420 C CD     . PRO B 2 70  ? 60.322 32.919  11.618 1.00 7.79  ? 70  PRO A CD     1 
ATOM   2421 N N      . VAL B 2 71  ? 61.457 29.850  13.204 1.00 10.48 ? 71  VAL A N      1 
ATOM   2422 C CA     . VAL B 2 71  ? 62.173 28.914  14.078 1.00 12.43 ? 71  VAL A CA     1 
ATOM   2423 C C      . VAL B 2 71  ? 61.291 27.852  14.682 1.00 11.85 ? 71  VAL A C      1 
ATOM   2424 O O      . VAL B 2 71  ? 61.751 27.065  15.520 1.00 12.82 ? 71  VAL A O      1 
ATOM   2425 C CB     . VAL B 2 71  ? 62.899 29.642  15.247 1.00 11.85 ? 71  VAL A CB     1 
ATOM   2426 C CG1    . VAL B 2 71  ? 63.743 30.783  14.718 1.00 12.24 ? 71  VAL A CG1    1 
ATOM   2427 C CG2    . VAL B 2 71  ? 61.905 30.169  16.249 1.00 12.40 ? 71  VAL A CG2    1 
ATOM   2428 H H      . VAL B 2 71  ? 61.165 30.715  13.561 1.00 20.00 ? 71  VAL A H      1 
ATOM   2429 N N      . LYS B 2 72  ? 60.027 27.831  14.283 1.00 12.88 ? 72  LYS A N      1 
ATOM   2430 C CA     . LYS B 2 72  ? 59.133 26.853  14.854 1.00 14.77 ? 72  LYS A CA     1 
ATOM   2431 C C      . LYS B 2 72  ? 58.349 26.081  13.813 1.00 11.17 ? 72  LYS A C      1 
ATOM   2432 O O      . LYS B 2 72  ? 57.709 25.071  14.121 1.00 10.56 ? 72  LYS A O      1 
ATOM   2433 C CB     . LYS B 2 72  ? 58.207 27.557  15.840 1.00 20.24 ? 72  LYS A CB     1 
ATOM   2434 C CG     . LYS B 2 72  ? 58.988 28.399  16.815 1.00 24.34 ? 72  LYS A CG     1 
ATOM   2435 C CD     . LYS B 2 72  ? 58.534 28.246  18.248 1.00 27.58 ? 72  LYS A CD     1 
ATOM   2436 C CE     . LYS B 2 72  ? 57.221 28.979  18.468 1.00 32.35 ? 72  LYS A CE     1 
ATOM   2437 N NZ     . LYS B 2 72  ? 56.841 29.035  19.909 1.00 32.64 ? 72  LYS A NZ     1 
ATOM   2438 H H      . LYS B 2 72  ? 59.700 28.445  13.601 1.00 20.00 ? 72  LYS A H      1 
ATOM   2439 H HZ1    . LYS B 2 72  ? 57.661 29.320  20.474 1.00 20.00 ? 72  LYS A HZ1    1 
ATOM   2440 H HZ2    . LYS B 2 72  ? 56.074 29.735  20.040 1.00 20.00 ? 72  LYS A HZ2    1 
ATOM   2441 H HZ3    . LYS B 2 72  ? 56.501 28.104  20.227 1.00 20.00 ? 72  LYS A HZ3    1 
ATOM   2442 N N      . GLU B 2 73  ? 58.446 26.524  12.567 1.00 8.53  ? 73  GLU A N      1 
ATOM   2443 C CA     . GLU B 2 73  ? 57.710 25.898  11.478 1.00 6.16  ? 73  GLU A CA     1 
ATOM   2444 C C      . GLU B 2 73  ? 58.580 25.034  10.601 1.00 6.83  ? 73  GLU A C      1 
ATOM   2445 O O      . GLU B 2 73  ? 59.795 25.216  10.538 1.00 7.72  ? 73  GLU A O      1 
ATOM   2446 C CB     . GLU B 2 73  ? 57.070 26.984  10.657 1.00 2.73  ? 73  GLU A CB     1 
ATOM   2447 C CG     . GLU B 2 73  ? 56.182 27.841  11.516 1.00 2.00  ? 73  GLU A CG     1 
ATOM   2448 C CD     . GLU B 2 73  ? 56.114 29.292  11.067 1.00 3.05  ? 73  GLU A CD     1 
ATOM   2449 O OE1    . GLU B 2 73  ? 56.669 29.583  9.977  1.00 2.76  ? 73  GLU A OE1    1 
ATOM   2450 O OE2    . GLU B 2 73  ? 55.502 30.126  11.789 1.00 2.00  ? 73  GLU A OE2    1 
ATOM   2451 H H      . GLU B 2 73  ? 59.099 27.220  12.353 1.00 20.00 ? 73  GLU A H      1 
ATOM   2452 N N      . ASP B 2 74  ? 57.958 24.096  9.908  1.00 9.87  ? 74  ASP A N      1 
ATOM   2453 C CA     . ASP B 2 74  ? 58.692 23.215  9.005  1.00 13.71 ? 74  ASP A CA     1 
ATOM   2454 C C      . ASP B 2 74  ? 57.826 22.850  7.817  1.00 12.04 ? 74  ASP A C      1 
ATOM   2455 O O      . ASP B 2 74  ? 56.611 22.631  7.939  1.00 10.86 ? 74  ASP A O      1 
ATOM   2456 C CB     . ASP B 2 74  ? 59.139 21.937  9.733  1.00 21.85 ? 74  ASP A CB     1 
ATOM   2457 C CG     . ASP B 2 74  ? 59.830 20.939  8.802  1.00 25.30 ? 74  ASP A CG     1 
ATOM   2458 O OD1    . ASP B 2 74  ? 60.661 21.383  7.977  1.00 27.47 ? 74  ASP A OD1    1 
ATOM   2459 O OD2    . ASP B 2 74  ? 59.546 19.719  8.904  1.00 27.92 ? 74  ASP A OD2    1 
ATOM   2460 H H      . ASP B 2 74  ? 56.976 23.996  10.012 1.00 20.00 ? 74  ASP A H      1 
ATOM   2461 N N      . ILE B 2 75  ? 58.468 22.711  6.671  1.00 9.74  ? 75  ILE A N      1 
ATOM   2462 C CA     . ILE B 2 75  ? 57.739 22.360  5.477  1.00 6.20  ? 75  ILE A CA     1 
ATOM   2463 C C      . ILE B 2 75  ? 56.945 21.075  5.628  1.00 6.59  ? 75  ILE A C      1 
ATOM   2464 O O      . ILE B 2 75  ? 55.920 20.942  4.980  1.00 7.75  ? 75  ILE A O      1 
ATOM   2465 C CB     . ILE B 2 75  ? 58.682 22.221  4.294  1.00 6.10  ? 75  ILE A CB     1 
ATOM   2466 C CG1    . ILE B 2 75  ? 57.910 22.334  2.996  1.00 6.36  ? 75  ILE A CG1    1 
ATOM   2467 C CG2    . ILE B 2 75  ? 59.430 20.924  4.378  1.00 7.96  ? 75  ILE A CG2    1 
ATOM   2468 C CD1    . ILE B 2 75  ? 57.272 23.669  2.861  1.00 7.22  ? 75  ILE A CD1    1 
ATOM   2469 H H      . ILE B 2 75  ? 59.450 22.781  6.658  1.00 20.00 ? 75  ILE A H      1 
ATOM   2470 N N      . GLU B 2 76  ? 57.385 20.143  6.477  1.00 4.46  ? 76  GLU A N      1 
ATOM   2471 C CA     . GLU B 2 76  ? 56.651 18.871  6.630  1.00 5.88  ? 76  GLU A CA     1 
ATOM   2472 C C      . GLU B 2 76  ? 55.187 19.117  6.988  1.00 3.50  ? 76  GLU A C      1 
ATOM   2473 O O      . GLU B 2 76  ? 54.262 18.459  6.488  1.00 2.01  ? 76  GLU A O      1 
ATOM   2474 C CB     . GLU B 2 76  ? 57.295 17.971  7.697  1.00 11.81 ? 76  GLU A CB     1 
ATOM   2475 C CG     . GLU B 2 76  ? 56.420 16.784  8.147  1.00 17.00 ? 76  GLU A CG     1 
ATOM   2476 C CD     . GLU B 2 76  ? 57.055 15.934  9.281  1.00 23.93 ? 76  GLU A CD     1 
ATOM   2477 O OE1    . GLU B 2 76  ? 58.210 16.240  9.691  1.00 22.32 ? 76  GLU A OE1    1 
ATOM   2478 O OE2    . GLU B 2 76  ? 56.408 14.959  9.754  1.00 24.49 ? 76  GLU A OE2    1 
ATOM   2479 H H      . GLU B 2 76  ? 58.204 20.281  6.980  1.00 20.00 ? 76  GLU A H      1 
ATOM   2480 N N      . TYR B 2 77  ? 55.002 20.122  7.838  1.00 3.47  ? 77  TYR A N      1 
ATOM   2481 C CA     . TYR B 2 77  ? 53.684 20.494  8.325  1.00 2.00  ? 77  TYR A CA     1 
ATOM   2482 C C      . TYR B 2 77  ? 52.799 21.121  7.265  1.00 2.00  ? 77  TYR A C      1 
ATOM   2483 O O      . TYR B 2 77  ? 51.618 20.826  7.214  1.00 2.00  ? 77  TYR A O      1 
ATOM   2484 C CB     . TYR B 2 77  ? 53.790 21.439  9.534  1.00 2.01  ? 77  TYR A CB     1 
ATOM   2485 C CG     . TYR B 2 77  ? 54.671 20.897  10.644 1.00 2.00  ? 77  TYR A CG     1 
ATOM   2486 C CD1    . TYR B 2 77  ? 54.468 19.625  11.155 1.00 2.00  ? 77  TYR A CD1    1 
ATOM   2487 C CD2    . TYR B 2 77  ? 55.744 21.642  11.144 1.00 2.00  ? 77  TYR A CD2    1 
ATOM   2488 C CE1    . TYR B 2 77  ? 55.305 19.106  12.120 1.00 2.00  ? 77  TYR A CE1    1 
ATOM   2489 C CE2    . TYR B 2 77  ? 56.576 21.130  12.114 1.00 2.00  ? 77  TYR A CE2    1 
ATOM   2490 C CZ     . TYR B 2 77  ? 56.351 19.860  12.593 1.00 2.00  ? 77  TYR A CZ     1 
ATOM   2491 O OH     . TYR B 2 77  ? 57.187 19.326  13.550 1.00 2.00  ? 77  TYR A OH     1 
ATOM   2492 H H      . TYR B 2 77  ? 55.788 20.641  8.145  1.00 20.00 ? 77  TYR A H      1 
ATOM   2493 H HH     . TYR B 2 77  ? 56.854 18.452  13.821 1.00 20.00 ? 77  TYR A HH     1 
ATOM   2494 N N      . VAL B 2 78  ? 53.350 21.956  6.391  1.00 2.01  ? 78  VAL A N      1 
ATOM   2495 C CA     . VAL B 2 78  ? 52.496 22.582  5.387  1.00 2.00  ? 78  VAL A CA     1 
ATOM   2496 C C      . VAL B 2 78  ? 51.881 21.515  4.482  1.00 2.11  ? 78  VAL A C      1 
ATOM   2497 O O      . VAL B 2 78  ? 50.718 21.623  4.111  1.00 2.00  ? 78  VAL A O      1 
ATOM   2498 C CB     . VAL B 2 78  ? 53.215 23.669  4.546  1.00 2.00  ? 78  VAL A CB     1 
ATOM   2499 C CG1    . VAL B 2 78  ? 54.317 24.304  5.338  1.00 2.21  ? 78  VAL A CG1    1 
ATOM   2500 C CG2    . VAL B 2 78  ? 53.712 23.109  3.229  1.00 2.00  ? 78  VAL A CG2    1 
ATOM   2501 H H      . VAL B 2 78  ? 54.302 22.146  6.422  1.00 20.00 ? 78  VAL A H      1 
ATOM   2502 N N      . GLU B 2 79  ? 52.649 20.464  4.183  1.00 4.61  ? 79  GLU A N      1 
ATOM   2503 C CA     . GLU B 2 79  ? 52.182 19.383  3.328  1.00 3.34  ? 79  GLU A CA     1 
ATOM   2504 C C      . GLU B 2 79  ? 51.179 18.507  4.035  1.00 3.82  ? 79  GLU A C      1 
ATOM   2505 O O      . GLU B 2 79  ? 50.182 18.118  3.435  1.00 2.01  ? 79  GLU A O      1 
ATOM   2506 C CB     . GLU B 2 79  ? 53.331 18.548  2.824  1.00 6.26  ? 79  GLU A CB     1 
ATOM   2507 C CG     . GLU B 2 79  ? 54.044 19.202  1.649  1.00 14.90 ? 79  GLU A CG     1 
ATOM   2508 C CD     . GLU B 2 79  ? 53.107 19.518  0.445  1.00 20.96 ? 79  GLU A CD     1 
ATOM   2509 O OE1    . GLU B 2 79  ? 52.111 18.786  0.216  1.00 22.74 ? 79  GLU A OE1    1 
ATOM   2510 O OE2    . GLU B 2 79  ? 53.385 20.500  -0.286 1.00 20.87 ? 79  GLU A OE2    1 
ATOM   2511 H H      . GLU B 2 79  ? 53.564 20.440  4.537  1.00 20.00 ? 79  GLU A H      1 
ATOM   2512 N N      . SER B 2 80  ? 51.407 18.225  5.314  1.00 2.00  ? 80  SER A N      1 
ATOM   2513 C CA     . SER B 2 80  ? 50.487 17.403  6.093  1.00 2.00  ? 80  SER A CA     1 
ATOM   2514 C C      . SER B 2 80  ? 49.181 18.145  6.359  1.00 2.00  ? 80  SER A C      1 
ATOM   2515 O O      . SER B 2 80  ? 48.095 17.563  6.319  1.00 2.00  ? 80  SER A O      1 
ATOM   2516 C CB     . SER B 2 80  ? 51.118 17.002  7.418  1.00 2.01  ? 80  SER A CB     1 
ATOM   2517 O OG     . SER B 2 80  ? 51.695 18.135  8.050  1.00 2.01  ? 80  SER A OG     1 
ATOM   2518 H H      . SER B 2 80  ? 52.201 18.582  5.777  1.00 20.00 ? 80  SER A H      1 
ATOM   2519 H HG     . SER B 2 80  ? 52.128 17.824  8.859  1.00 20.00 ? 80  SER A HG     1 
ATOM   2520 N N      . ILE B 2 81  ? 49.287 19.450  6.581  1.00 2.00  ? 81  ILE A N      1 
ATOM   2521 C CA     . ILE B 2 81  ? 48.124 20.303  6.836  1.00 2.01  ? 81  ILE A CA     1 
ATOM   2522 C C      . ILE B 2 81  ? 47.195 20.374  5.628  1.00 2.00  ? 81  ILE A C      1 
ATOM   2523 O O      . ILE B 2 81  ? 45.981 20.201  5.762  1.00 2.01  ? 81  ILE A O      1 
ATOM   2524 C CB     . ILE B 2 81  ? 48.538 21.701  7.296  1.00 2.00  ? 81  ILE A CB     1 
ATOM   2525 C CG1    . ILE B 2 81  ? 49.199 21.608  8.667  1.00 2.01  ? 81  ILE A CG1    1 
ATOM   2526 C CG2    . ILE B 2 81  ? 47.325 22.546  7.442  1.00 2.00  ? 81  ILE A CG2    1 
ATOM   2527 C CD1    . ILE B 2 81  ? 49.729 22.853  9.173  1.00 2.01  ? 81  ILE A CD1    1 
ATOM   2528 H H      . ILE B 2 81  ? 50.179 19.831  6.628  1.00 20.00 ? 81  ILE A H      1 
ATOM   2529 N N      . LYS B 2 82  ? 47.771 20.575  4.448  1.00 2.00  ? 82  LYS A N      1 
ATOM   2530 C CA     . LYS B 2 82  ? 46.972 20.601  3.221  1.00 6.35  ? 82  LYS A CA     1 
ATOM   2531 C C      . LYS B 2 82  ? 46.285 19.236  3.055  1.00 9.96  ? 82  LYS A C      1 
ATOM   2532 O O      . LYS B 2 82  ? 45.132 19.129  2.625  1.00 7.53  ? 82  LYS A O      1 
ATOM   2533 C CB     . LYS B 2 82  ? 47.886 20.847  2.015  1.00 6.43  ? 82  LYS A CB     1 
ATOM   2534 C CG     . LYS B 2 82  ? 48.580 22.150  2.065  1.00 5.92  ? 82  LYS A CG     1 
ATOM   2535 C CD     . LYS B 2 82  ? 49.673 22.221  1.064  1.00 5.78  ? 82  LYS A CD     1 
ATOM   2536 C CE     . LYS B 2 82  ? 49.144 22.040  -0.316 1.00 6.02  ? 82  LYS A CE     1 
ATOM   2537 N NZ     . LYS B 2 82  ? 50.247 22.425  -1.242 1.00 8.63  ? 82  LYS A NZ     1 
ATOM   2538 H H      . LYS B 2 82  ? 48.755 20.692  4.408  1.00 20.00 ? 82  LYS A H      1 
ATOM   2539 H HZ1    . LYS B 2 82  ? 51.170 22.031  -0.925 1.00 20.00 ? 82  LYS A HZ1    1 
ATOM   2540 H HZ2    . LYS B 2 82  ? 50.062 22.123  -2.209 1.00 20.00 ? 82  LYS A HZ2    1 
ATOM   2541 H HZ3    . LYS B 2 82  ? 50.355 23.480  -1.235 1.00 20.00 ? 82  LYS A HZ3    1 
ATOM   2542 N N      . ASN B 2 83  ? 47.005 18.199  3.458  1.00 16.00 ? 83  ASN A N      1 
ATOM   2543 C CA     . ASN B 2 83  ? 46.528 16.835  3.373  1.00 22.10 ? 83  ASN A CA     1 
ATOM   2544 C C      . ASN B 2 83  ? 45.283 16.613  4.205  1.00 19.24 ? 83  ASN A C      1 
ATOM   2545 O O      . ASN B 2 83  ? 44.259 16.200  3.681  1.00 17.58 ? 83  ASN A O      1 
ATOM   2546 C CB     . ASN B 2 83  ? 47.627 15.907  3.849  1.00 33.83 ? 83  ASN A CB     1 
ATOM   2547 C CG     . ASN B 2 83  ? 47.952 14.843  2.850  1.00 41.52 ? 83  ASN A CG     1 
ATOM   2548 O OD1    . ASN B 2 83  ? 47.587 13.676  3.036  1.00 43.13 ? 83  ASN A OD1    1 
ATOM   2549 N ND2    . ASN B 2 83  ? 48.663 15.216  1.787  1.00 47.55 ? 83  ASN A ND2    1 
ATOM   2550 H H      . ASN B 2 83  ? 47.920 18.359  3.781  1.00 20.00 ? 83  ASN A H      1 
ATOM   2551 H HD21   . ASN B 2 83  ? 48.874 14.511  1.138  1.00 20.00 ? 83  ASN A HD21   1 
ATOM   2552 H HD22   . ASN B 2 83  ? 48.951 16.139  1.697  1.00 20.00 ? 83  ASN A HD22   1 
ATOM   2553 N N      . ASP B 2 84  ? 45.357 16.917  5.498  1.00 15.05 ? 84  ASP A N      1 
ATOM   2554 C CA     . ASP B 2 84  ? 44.213 16.706  6.380  1.00 11.54 ? 84  ASP A CA     1 
ATOM   2555 C C      . ASP B 2 84  ? 42.998 17.565  6.030  1.00 8.16  ? 84  ASP A C      1 
ATOM   2556 O O      . ASP B 2 84  ? 41.841 17.140  6.209  1.00 6.30  ? 84  ASP A O      1 
ATOM   2557 C CB     . ASP B 2 84  ? 44.590 16.929  7.844  1.00 15.24 ? 84  ASP A CB     1 
ATOM   2558 C CG     . ASP B 2 84  ? 45.691 15.998  8.328  1.00 16.13 ? 84  ASP A CG     1 
ATOM   2559 O OD1    . ASP B 2 84  ? 45.548 14.769  8.274  1.00 20.35 ? 84  ASP A OD1    1 
ATOM   2560 O OD2    . ASP B 2 84  ? 46.716 16.507  8.821  1.00 17.10 ? 84  ASP A OD2    1 
ATOM   2561 H H      . ASP B 2 84  ? 46.202 17.259  5.870  1.00 20.00 ? 84  ASP A H      1 
ATOM   2562 N N      . VAL B 2 85  ? 43.241 18.777  5.540  1.00 5.24  ? 85  VAL A N      1 
ATOM   2563 C CA     . VAL B 2 85  ? 42.113 19.641  5.194  1.00 2.00  ? 85  VAL A CA     1 
ATOM   2564 C C      . VAL B 2 85  ? 41.273 18.987  4.100  1.00 2.00  ? 85  VAL A C      1 
ATOM   2565 O O      . VAL B 2 85  ? 40.049 18.897  4.223  1.00 2.00  ? 85  VAL A O      1 
ATOM   2566 C CB     . VAL B 2 85  ? 42.525 21.088  4.795  1.00 2.00  ? 85  VAL A CB     1 
ATOM   2567 C CG1    . VAL B 2 85  ? 41.307 21.892  4.438  1.00 2.01  ? 85  VAL A CG1    1 
ATOM   2568 C CG2    . VAL B 2 85  ? 43.236 21.760  5.952  1.00 2.01  ? 85  VAL A CG2    1 
ATOM   2569 H H      . VAL B 2 85  ? 44.173 19.083  5.396  1.00 20.00 ? 85  VAL A H      1 
ATOM   2570 N N      . GLU B 2 86  ? 41.934 18.445  3.083  1.00 2.00  ? 86  GLU A N      1 
ATOM   2571 C CA     . GLU B 2 86  ? 41.218 17.785  2.000  1.00 2.01  ? 86  GLU A CA     1 
ATOM   2572 C C      . GLU B 2 86  ? 40.535 16.504  2.481  1.00 2.77  ? 86  GLU A C      1 
ATOM   2573 O O      . GLU B 2 86  ? 39.371 16.238  2.154  1.00 2.39  ? 86  GLU A O      1 
ATOM   2574 C CB     . GLU B 2 86  ? 42.172 17.449  0.870  1.00 2.00  ? 86  GLU A CB     1 
ATOM   2575 C CG     . GLU B 2 86  ? 42.826 18.671  0.292  1.00 2.00  ? 86  GLU A CG     1 
ATOM   2576 C CD     . GLU B 2 86  ? 43.482 18.413  -1.038 1.00 4.62  ? 86  GLU A CD     1 
ATOM   2577 O OE1    . GLU B 2 86  ? 44.646 17.922  -1.057 1.00 4.79  ? 86  GLU A OE1    1 
ATOM   2578 O OE2    . GLU B 2 86  ? 42.819 18.716  -2.055 1.00 7.31  ? 86  GLU A OE2    1 
ATOM   2579 H H      . GLU B 2 86  ? 42.914 18.488  3.061  1.00 20.00 ? 86  GLU A H      1 
ATOM   2580 N N      . TRP B 2 87  ? 41.271 15.711  3.255  1.00 2.24  ? 87  TRP A N      1 
ATOM   2581 C CA     . TRP B 2 87  ? 40.739 14.474  3.763  1.00 2.56  ? 87  TRP A CA     1 
ATOM   2582 C C      . TRP B 2 87  ? 39.399 14.667  4.464  1.00 2.00  ? 87  TRP A C      1 
ATOM   2583 O O      . TRP B 2 87  ? 38.522 13.818  4.362  1.00 2.00  ? 87  TRP A O      1 
ATOM   2584 C CB     . TRP B 2 87  ? 41.748 13.805  4.688  1.00 5.97  ? 87  TRP A CB     1 
ATOM   2585 C CG     . TRP B 2 87  ? 41.233 12.523  5.251  1.00 9.91  ? 87  TRP A CG     1 
ATOM   2586 C CD1    . TRP B 2 87  ? 41.122 11.327  4.604  1.00 9.31  ? 87  TRP A CD1    1 
ATOM   2587 C CD2    . TRP B 2 87  ? 40.697 12.321  6.574  1.00 9.73  ? 87  TRP A CD2    1 
ATOM   2588 N NE1    . TRP B 2 87  ? 40.545 10.401  5.435  1.00 9.55  ? 87  TRP A NE1    1 
ATOM   2589 C CE2    . TRP B 2 87  ? 40.273 10.985  6.644  1.00 10.40 ? 87  TRP A CE2    1 
ATOM   2590 C CE3    . TRP B 2 87  ? 40.524 13.146  7.692  1.00 11.45 ? 87  TRP A CE3    1 
ATOM   2591 C CZ2    . TRP B 2 87  ? 39.695 10.451  7.792  1.00 10.63 ? 87  TRP A CZ2    1 
ATOM   2592 C CZ3    . TRP B 2 87  ? 39.947 12.616  8.830  1.00 10.16 ? 87  TRP A CZ3    1 
ATOM   2593 C CH2    . TRP B 2 87  ? 39.536 11.280  8.868  1.00 10.71 ? 87  TRP A CH2    1 
ATOM   2594 H H      . TRP B 2 87  ? 42.190 15.970  3.475  1.00 20.00 ? 87  TRP A H      1 
ATOM   2595 H HE1    . TRP B 2 87  ? 40.363 9.468   5.195  1.00 20.00 ? 87  TRP A HE1    1 
ATOM   2596 N N      . LEU B 2 88  ? 39.230 15.789  5.162  1.00 2.00  ? 88  LEU A N      1 
ATOM   2597 C CA     . LEU B 2 88  ? 37.974 16.056  5.883  1.00 3.52  ? 88  LEU A CA     1 
ATOM   2598 C C      . LEU B 2 88  ? 36.887 16.394  4.902  1.00 4.32  ? 88  LEU A C      1 
ATOM   2599 O O      . LEU B 2 88  ? 35.734 16.527  5.283  1.00 3.80  ? 88  LEU A O      1 
ATOM   2600 C CB     . LEU B 2 88  ? 38.120 17.203  6.888  1.00 3.24  ? 88  LEU A CB     1 
ATOM   2601 C CG     . LEU B 2 88  ? 38.779 16.943  8.241  1.00 2.76  ? 88  LEU A CG     1 
ATOM   2602 C CD1    . LEU B 2 88  ? 39.137 18.276  8.866  1.00 4.79  ? 88  LEU A CD1    1 
ATOM   2603 C CD2    . LEU B 2 88  ? 37.855 16.144  9.145  1.00 2.00  ? 88  LEU A CD2    1 
ATOM   2604 H H      . LEU B 2 88  ? 39.975 16.432  5.218  1.00 20.00 ? 88  LEU A H      1 
ATOM   2605 N N      . GLY B 2 89  ? 37.294 16.597  3.652  1.00 2.77  ? 89  GLY A N      1 
ATOM   2606 C CA     . GLY B 2 89  ? 36.359 16.888  2.596  1.00 2.20  ? 89  GLY A CA     1 
ATOM   2607 C C      . GLY B 2 89  ? 36.085 18.343  2.351  1.00 3.71  ? 89  GLY A C      1 
ATOM   2608 O O      . GLY B 2 89  ? 34.960 18.678  2.016  1.00 7.52  ? 89  GLY A O      1 
ATOM   2609 H H      . GLY B 2 89  ? 38.218 16.537  3.459  1.00 20.00 ? 89  GLY A H      1 
ATOM   2610 N N      . PHE B 2 90  ? 37.097 19.202  2.461  1.00 4.02  ? 90  PHE A N      1 
ATOM   2611 C CA     . PHE B 2 90  ? 36.924 20.637  2.243  1.00 2.00  ? 90  PHE A CA     1 
ATOM   2612 C C      . PHE B 2 90  ? 37.973 21.127  1.279  1.00 2.91  ? 90  PHE A C      1 
ATOM   2613 O O      . PHE B 2 90  ? 39.083 20.597  1.245  1.00 2.00  ? 90  PHE A O      1 
ATOM   2614 C CB     . PHE B 2 90  ? 37.087 21.390  3.552  1.00 2.01  ? 90  PHE A CB     1 
ATOM   2615 C CG     . PHE B 2 90  ? 36.014 21.122  4.543  1.00 2.00  ? 90  PHE A CG     1 
ATOM   2616 C CD1    . PHE B 2 90  ? 34.724 21.583  4.328  1.00 2.01  ? 90  PHE A CD1    1 
ATOM   2617 C CD2    . PHE B 2 90  ? 36.293 20.445  5.722  1.00 2.00  ? 90  PHE A CD2    1 
ATOM   2618 C CE1    . PHE B 2 90  ? 33.732 21.379  5.272  1.00 2.01  ? 90  PHE A CE1    1 
ATOM   2619 C CE2    . PHE B 2 90  ? 35.289 20.238  6.685  1.00 2.00  ? 90  PHE A CE2    1 
ATOM   2620 C CZ     . PHE B 2 90  ? 34.007 20.704  6.452  1.00 2.01  ? 90  PHE A CZ     1 
ATOM   2621 H H      . PHE B 2 90  ? 38.003 18.872  2.663  1.00 20.00 ? 90  PHE A H      1 
ATOM   2622 N N      . HIS B 2 91  ? 37.631 22.111  0.464  1.00 4.19  ? 91  HIS A N      1 
ATOM   2623 C CA     . HIS B 2 91  ? 38.591 22.653  -0.478 1.00 2.10  ? 91  HIS A CA     1 
ATOM   2624 C C      . HIS B 2 91  ? 38.601 24.149  -0.311 1.00 2.00  ? 91  HIS A C      1 
ATOM   2625 O O      . HIS B 2 91  ? 37.565 24.787  -0.090 1.00 4.55  ? 91  HIS A O      1 
ATOM   2626 C CB     . HIS B 2 91  ? 38.231 22.283  -1.896 1.00 5.68  ? 91  HIS A CB     1 
ATOM   2627 C CG     . HIS B 2 91  ? 38.255 20.808  -2.140 1.00 9.60  ? 91  HIS A CG     1 
ATOM   2628 N ND1    . HIS B 2 91  ? 39.426 20.070  -2.088 1.00 10.39 ? 91  HIS A ND1    1 
ATOM   2629 C CD2    . HIS B 2 91  ? 37.255 19.920  -2.367 1.00 11.03 ? 91  HIS A CD2    1 
ATOM   2630 C CE1    . HIS B 2 91  ? 39.139 18.798  -2.265 1.00 11.58 ? 91  HIS A CE1    1 
ATOM   2631 N NE2    . HIS B 2 91  ? 37.830 18.676  -2.439 1.00 12.23 ? 91  HIS A NE2    1 
ATOM   2632 H H      . HIS B 2 91  ? 36.722 22.480  0.492  1.00 20.00 ? 91  HIS A H      1 
ATOM   2633 H HD1    . HIS B 2 91  ? 40.323 20.428  -1.942 1.00 20.00 ? 91  HIS A HD1    1 
ATOM   2634 H HE2    . HIS B 2 91  ? 37.336 17.846  -2.630 1.00 20.00 ? 91  HIS A HE2    1 
ATOM   2635 N N      . TRP B 2 92  ? 39.795 24.702  -0.365 1.00 2.00  ? 92  TRP A N      1 
ATOM   2636 C CA     . TRP B 2 92  ? 39.946 26.118  -0.195 1.00 2.23  ? 92  TRP A CA     1 
ATOM   2637 C C      . TRP B 2 92  ? 39.657 26.888  -1.459 1.00 4.55  ? 92  TRP A C      1 
ATOM   2638 O O      . TRP B 2 92  ? 39.487 26.308  -2.540 1.00 7.14  ? 92  TRP A O      1 
ATOM   2639 C CB     . TRP B 2 92  ? 41.320 26.441  0.325  1.00 2.01  ? 92  TRP A CB     1 
ATOM   2640 C CG     . TRP B 2 92  ? 42.378 25.672  -0.303 1.00 2.01  ? 92  TRP A CG     1 
ATOM   2641 C CD1    . TRP B 2 92  ? 43.310 26.142  -1.182 1.00 2.01  ? 92  TRP A CD1    1 
ATOM   2642 C CD2    . TRP B 2 92  ? 42.768 24.345  0.038  1.00 2.00  ? 92  TRP A CD2    1 
ATOM   2643 N NE1    . TRP B 2 92  ? 44.280 25.192  -1.382 1.00 2.00  ? 92  TRP A NE1    1 
ATOM   2644 C CE2    . TRP B 2 92  ? 43.975 24.074  -0.643 1.00 2.00  ? 92  TRP A CE2    1 
ATOM   2645 C CE3    . TRP B 2 92  ? 42.220 23.353  0.873  1.00 2.01  ? 92  TRP A CE3    1 
ATOM   2646 C CZ2    . TRP B 2 92  ? 44.652 22.859  -0.515 1.00 2.00  ? 92  TRP A CZ2    1 
ATOM   2647 C CZ3    . TRP B 2 92  ? 42.884 22.148  0.998  1.00 2.01  ? 92  TRP A CZ3    1 
ATOM   2648 C CH2    . TRP B 2 92  ? 44.093 21.909  0.307  1.00 2.00  ? 92  TRP A CH2    1 
ATOM   2649 H H      . TRP B 2 92  ? 40.571 24.158  -0.576 1.00 20.00 ? 92  TRP A H      1 
ATOM   2650 H HE1    . TRP B 2 92  ? 45.036 25.274  -1.990 1.00 20.00 ? 92  TRP A HE1    1 
ATOM   2651 N N      . SER B 2 93  ? 39.634 28.204  -1.317 1.00 4.21  ? 93  SER A N      1 
ATOM   2652 C CA     . SER B 2 93  ? 39.353 29.076  -2.413 1.00 4.64  ? 93  SER A CA     1 
ATOM   2653 C C      . SER B 2 93  ? 40.647 29.420  -3.088 1.00 4.37  ? 93  SER A C      1 
ATOM   2654 O O      . SER B 2 93  ? 41.602 29.857  -2.443 1.00 6.35  ? 93  SER A O      1 
ATOM   2655 C CB     . SER B 2 93  ? 38.712 30.327  -1.867 1.00 6.66  ? 93  SER A CB     1 
ATOM   2656 O OG     . SER B 2 93  ? 38.185 31.075  -2.921 1.00 11.66 ? 93  SER A OG     1 
ATOM   2657 H H      . SER B 2 93  ? 39.868 28.598  -0.448 1.00 20.00 ? 93  SER A H      1 
ATOM   2658 H HG     . SER B 2 93  ? 37.774 31.859  -2.570 1.00 20.00 ? 93  SER A HG     1 
ATOM   2659 N N      . GLY B 2 94  ? 40.698 29.204  -4.386 1.00 2.00  ? 94  GLY A N      1 
ATOM   2660 C CA     . GLY B 2 94  ? 41.906 29.548  -5.113 1.00 2.00  ? 94  GLY A CA     1 
ATOM   2661 C C      . GLY B 2 94  ? 43.175 28.850  -4.640 1.00 2.00  ? 94  GLY A C      1 
ATOM   2662 O O      . GLY B 2 94  ? 43.174 27.665  -4.289 1.00 2.00  ? 94  GLY A O      1 
ATOM   2663 H H      . GLY B 2 94  ? 39.951 28.756  -4.830 1.00 20.00 ? 94  GLY A H      1 
ATOM   2664 N N      . ASN B 2 95  ? 44.284 29.564  -4.686 1.00 2.00  ? 95  ASN A N      1 
ATOM   2665 C CA     . ASN B 2 95  ? 45.550 28.987  -4.274 1.00 4.17  ? 95  ASN A CA     1 
ATOM   2666 C C      . ASN B 2 95  ? 45.818 29.040  -2.781 1.00 2.91  ? 95  ASN A C      1 
ATOM   2667 O O      . ASN B 2 95  ? 45.162 29.781  -2.046 1.00 4.95  ? 95  ASN A O      1 
ATOM   2668 C CB     . ASN B 2 95  ? 46.700 29.656  -4.999 1.00 9.43  ? 95  ASN A CB     1 
ATOM   2669 C CG     . ASN B 2 95  ? 46.966 29.065  -6.371 1.00 11.43 ? 95  ASN A CG     1 
ATOM   2670 O OD1    . ASN B 2 95  ? 48.058 29.247  -6.917 1.00 14.99 ? 95  ASN A OD1    1 
ATOM   2671 N ND2    . ASN B 2 95  ? 45.981 28.343  -6.936 1.00 13.86 ? 95  ASN A ND2    1 
ATOM   2672 H H      . ASN B 2 95  ? 44.238 30.481  -4.924 1.00 20.00 ? 95  ASN A H      1 
ATOM   2673 H HD21   . ASN B 2 95  ? 46.125 27.928  -7.824 1.00 20.00 ? 95  ASN A HD21   1 
ATOM   2674 H HD22   . ASN B 2 95  ? 45.122 28.169  -6.462 1.00 20.00 ? 95  ASN A HD22   1 
ATOM   2675 N N      . VAL B 2 96  ? 46.770 28.225  -2.330 1.00 2.34  ? 96  VAL A N      1 
ATOM   2676 C CA     . VAL B 2 96  ? 47.137 28.200  -0.923 1.00 2.01  ? 96  VAL A CA     1 
ATOM   2677 C C      . VAL B 2 96  ? 47.854 29.513  -0.727 1.00 2.00  ? 96  VAL A C      1 
ATOM   2678 O O      . VAL B 2 96  ? 48.501 30.001  -1.658 1.00 2.01  ? 96  VAL A O      1 
ATOM   2679 C CB     . VAL B 2 96  ? 48.075 27.029  -0.618 1.00 2.01  ? 96  VAL A CB     1 
ATOM   2680 C CG1    . VAL B 2 96  ? 48.862 27.280  0.625  1.00 2.01  ? 96  VAL A CG1    1 
ATOM   2681 C CG2    . VAL B 2 96  ? 47.279 25.760  -0.456 1.00 2.01  ? 96  VAL A CG2    1 
ATOM   2682 H H      . VAL B 2 96  ? 47.211 27.616  -2.950 1.00 20.00 ? 96  VAL A H      1 
ATOM   2683 N N      . ARG B 2 97  ? 47.653 30.142  0.424  1.00 2.00  ? 97  ARG A N      1 
ATOM   2684 C CA     . ARG B 2 97  ? 48.311 31.416  0.686  1.00 2.00  ? 97  ARG A CA     1 
ATOM   2685 C C      . ARG B 2 97  ? 49.237 31.292  1.869  1.00 2.01  ? 97  ARG A C      1 
ATOM   2686 O O      . ARG B 2 97  ? 49.121 30.394  2.686  1.00 2.00  ? 97  ARG A O      1 
ATOM   2687 C CB     . ARG B 2 97  ? 47.313 32.524  1.005  1.00 4.89  ? 97  ARG A CB     1 
ATOM   2688 C CG     . ARG B 2 97  ? 46.052 32.502  0.231  1.00 7.31  ? 97  ARG A CG     1 
ATOM   2689 C CD     . ARG B 2 97  ? 46.213 32.799  -1.244 1.00 12.68 ? 97  ARG A CD     1 
ATOM   2690 N NE     . ARG B 2 97  ? 44.921 32.580  -1.904 1.00 19.58 ? 97  ARG A NE     1 
ATOM   2691 C CZ     . ARG B 2 97  ? 43.996 33.520  -2.110 1.00 23.82 ? 97  ARG A CZ     1 
ATOM   2692 N NH1    . ARG B 2 97  ? 44.254 34.791  -1.820 1.00 26.27 ? 97  ARG A NH1    1 
ATOM   2693 N NH2    . ARG B 2 97  ? 42.839 33.199  -2.687 1.00 24.49 ? 97  ARG A NH2    1 
ATOM   2694 H H      . ARG B 2 97  ? 47.040 29.751  1.097  1.00 20.00 ? 97  ARG A H      1 
ATOM   2695 H HE     . ARG B 2 97  ? 44.721 31.665  -2.221 1.00 20.00 ? 97  ARG A HE     1 
ATOM   2696 H HH11   . ARG B 2 97  ? 45.146 35.023  -1.428 1.00 20.00 ? 97  ARG A HH11   1 
ATOM   2697 H HH12   . ARG B 2 97  ? 43.557 35.476  -1.955 1.00 20.00 ? 97  ARG A HH12   1 
ATOM   2698 H HH21   . ARG B 2 97  ? 42.665 32.242  -2.956 1.00 20.00 ? 97  ARG A HH21   1 
ATOM   2699 H HH22   . ARG B 2 97  ? 42.143 33.890  -2.827 1.00 20.00 ? 97  ARG A HH22   1 
ATOM   2700 N N      . TYR B 2 98  ? 50.130 32.253  1.996  1.00 2.01  ? 98  TYR A N      1 
ATOM   2701 C CA     . TYR B 2 98  ? 51.080 32.279  3.096  1.00 2.00  ? 98  TYR A CA     1 
ATOM   2702 C C      . TYR B 2 98  ? 51.216 33.720  3.571  1.00 2.00  ? 98  TYR A C      1 
ATOM   2703 O O      . TYR B 2 98  ? 51.145 34.650  2.779  1.00 2.00  ? 98  TYR A O      1 
ATOM   2704 C CB     . TYR B 2 98  ? 52.463 31.801  2.640  1.00 2.01  ? 98  TYR A CB     1 
ATOM   2705 C CG     . TYR B 2 98  ? 52.540 30.361  2.224  1.00 2.00  ? 98  TYR A CG     1 
ATOM   2706 C CD1    . TYR B 2 98  ? 51.994 29.939  1.016  1.00 2.00  ? 98  TYR A CD1    1 
ATOM   2707 C CD2    . TYR B 2 98  ? 53.167 29.415  3.025  1.00 2.01  ? 98  TYR A CD2    1 
ATOM   2708 C CE1    . TYR B 2 98  ? 52.066 28.617  0.615  1.00 2.00  ? 98  TYR A CE1    1 
ATOM   2709 C CE2    . TYR B 2 98  ? 53.246 28.095  2.634  1.00 2.01  ? 98  TYR A CE2    1 
ATOM   2710 C CZ     . TYR B 2 98  ? 52.691 27.704  1.428  1.00 2.01  ? 98  TYR A CZ     1 
ATOM   2711 O OH     . TYR B 2 98  ? 52.755 26.398  1.015  1.00 2.16  ? 98  TYR A OH     1 
ATOM   2712 H H      . TYR B 2 98  ? 50.160 32.944  1.310  1.00 20.00 ? 98  TYR A H      1 
ATOM   2713 H HH     . TYR B 2 98  ? 53.216 25.876  1.639  1.00 20.00 ? 98  TYR A HH     1 
ATOM   2714 N N      . SER B 2 99  ? 51.445 33.915  4.861  1.00 2.00  ? 99  SER A N      1 
ATOM   2715 C CA     . SER B 2 99  ? 51.626 35.253  5.355  1.00 2.01  ? 99  SER A CA     1 
ATOM   2716 C C      . SER B 2 99  ? 52.908 35.717  4.736  1.00 2.01  ? 99  SER A C      1 
ATOM   2717 O O      . SER B 2 99  ? 53.014 36.867  4.375  1.00 2.01  ? 99  SER A O      1 
ATOM   2718 C CB     . SER B 2 99  ? 51.726 35.273  6.858  1.00 2.01  ? 99  SER A CB     1 
ATOM   2719 O OG     . SER B 2 99  ? 50.466 35.064  7.445  1.00 2.01  ? 99  SER A OG     1 
ATOM   2720 H H      . SER B 2 99  ? 51.446 33.145  5.467  1.00 20.00 ? 99  SER A H      1 
ATOM   2721 H HG     . SER B 2 99  ? 50.604 35.056  8.383  1.00 20.00 ? 99  SER A HG     1 
ATOM   2722 N N      . SER B 2 100 ? 53.881 34.828  4.601  1.00 2.01  ? 100 SER A N      1 
ATOM   2723 C CA     . SER B 2 100 ? 55.132 35.195  3.981  1.00 2.01  ? 100 SER A CA     1 
ATOM   2724 C C      . SER B 2 100 ? 54.852 35.765  2.601  1.00 2.00  ? 100 SER A C      1 
ATOM   2725 O O      . SER B 2 100 ? 55.649 36.543  2.074  1.00 2.01  ? 100 SER A O      1 
ATOM   2726 C CB     . SER B 2 100 ? 56.058 33.992  3.856  1.00 2.00  ? 100 SER A CB     1 
ATOM   2727 O OG     . SER B 2 100 ? 55.352 32.861  3.382  1.00 2.00  ? 100 SER A OG     1 
ATOM   2728 H H      . SER B 2 100 ? 53.735 33.902  4.854  1.00 20.00 ? 100 SER A H      1 
ATOM   2729 H HG     . SER B 2 100 ? 55.963 32.121  3.351  1.00 20.00 ? 100 SER A HG     1 
ATOM   2730 N N      . ASP B 2 101 ? 53.712 35.413  2.010  1.00 2.00  ? 101 ASP A N      1 
ATOM   2731 C CA     . ASP B 2 101 ? 53.375 35.973  0.704  1.00 2.00  ? 101 ASP A CA     1 
ATOM   2732 C C      . ASP B 2 101 ? 53.300 37.486  0.867  1.00 2.00  ? 101 ASP A C      1 
ATOM   2733 O O      . ASP B 2 101 ? 53.548 38.215  -0.081 1.00 2.00  ? 101 ASP A O      1 
ATOM   2734 C CB     . ASP B 2 101 ? 52.018 35.496  0.194  1.00 2.01  ? 101 ASP A CB     1 
ATOM   2735 C CG     . ASP B 2 101 ? 52.070 34.153  -0.425 1.00 2.01  ? 101 ASP A CG     1 
ATOM   2736 O OD1    . ASP B 2 101 ? 53.129 33.526  -0.484 1.00 2.77  ? 101 ASP A OD1    1 
ATOM   2737 O OD2    . ASP B 2 101 ? 51.026 33.690  -0.885 1.00 2.00  ? 101 ASP A OD2    1 
ATOM   2738 H H      . ASP B 2 101 ? 53.118 34.763  2.426  1.00 20.00 ? 101 ASP A H      1 
ATOM   2739 N N      . TYR B 2 102 ? 52.975 37.971  2.061  1.00 2.01  ? 102 TYR A N      1 
ATOM   2740 C CA     . TYR B 2 102 ? 52.843 39.399  2.272  1.00 2.00  ? 102 TYR A CA     1 
ATOM   2741 C C      . TYR B 2 102 ? 54.011 40.080  2.948  1.00 2.01  ? 102 TYR A C      1 
ATOM   2742 O O      . TYR B 2 102 ? 53.890 41.191  3.430  1.00 2.02  ? 102 TYR A O      1 
ATOM   2743 C CB     . TYR B 2 102 ? 51.559 39.712  3.020  1.00 2.02  ? 102 TYR A CB     1 
ATOM   2744 C CG     . TYR B 2 102 ? 50.396 38.981  2.473  1.00 2.02  ? 102 TYR A CG     1 
ATOM   2745 C CD1    . TYR B 2 102 ? 49.992 39.167  1.164  1.00 2.01  ? 102 TYR A CD1    1 
ATOM   2746 C CD2    . TYR B 2 102 ? 49.732 38.047  3.232  1.00 2.01  ? 102 TYR A CD2    1 
ATOM   2747 C CE1    . TYR B 2 102 ? 48.945 38.426  0.615  1.00 2.01  ? 102 TYR A CE1    1 
ATOM   2748 C CE2    . TYR B 2 102 ? 48.678 37.289  2.693  1.00 2.01  ? 102 TYR A CE2    1 
ATOM   2749 C CZ     . TYR B 2 102 ? 48.296 37.488  1.386  1.00 2.01  ? 102 TYR A CZ     1 
ATOM   2750 O OH     . TYR B 2 102 ? 47.268 36.748  0.863  1.00 2.01  ? 102 TYR A OH     1 
ATOM   2751 H H      . TYR B 2 102 ? 52.827 37.368  2.746  1.00 20.00 ? 102 TYR A H      1 
ATOM   2752 H HH     . TYR B 2 102 ? 47.122 36.970  -0.041 1.00 20.00 ? 102 TYR A HH     1 
ATOM   2753 N N      . PHE B 2 103 ? 55.164 39.449  2.955  1.00 2.01  ? 103 PHE A N      1 
ATOM   2754 C CA     . PHE B 2 103 ? 56.313 40.052  3.617  1.00 2.01  ? 103 PHE A CA     1 
ATOM   2755 C C      . PHE B 2 103 ? 56.705 41.435  3.094  1.00 2.01  ? 103 PHE A C      1 
ATOM   2756 O O      . PHE B 2 103 ? 56.962 42.328  3.878  1.00 2.00  ? 103 PHE A O      1 
ATOM   2757 C CB     . PHE B 2 103 ? 57.505 39.098  3.623  1.00 2.01  ? 103 PHE A CB     1 
ATOM   2758 C CG     . PHE B 2 103 ? 57.433 38.041  4.690  1.00 2.01  ? 103 PHE A CG     1 
ATOM   2759 C CD1    . PHE B 2 103 ? 56.433 38.059  5.640  1.00 2.01  ? 103 PHE A CD1    1 
ATOM   2760 C CD2    . PHE B 2 103 ? 58.371 37.024  4.745  1.00 2.00  ? 103 PHE A CD2    1 
ATOM   2761 C CE1    . PHE B 2 103 ? 56.365 37.093  6.614  1.00 2.01  ? 103 PHE A CE1    1 
ATOM   2762 C CE2    . PHE B 2 103 ? 58.302 36.047  5.736  1.00 2.00  ? 103 PHE A CE2    1 
ATOM   2763 C CZ     . PHE B 2 103 ? 57.298 36.088  6.662  1.00 2.00  ? 103 PHE A CZ     1 
ATOM   2764 H H      . PHE B 2 103 ? 55.264 38.573  2.494  1.00 20.00 ? 103 PHE A H      1 
ATOM   2765 N N      . ASP B 2 104 ? 56.729 41.639  1.783  1.00 2.00  ? 104 ASP A N      1 
ATOM   2766 C CA     . ASP B 2 104 ? 57.095 42.950  1.251  1.00 2.01  ? 104 ASP A CA     1 
ATOM   2767 C C      . ASP B 2 104 ? 56.037 44.006  1.533  1.00 2.01  ? 104 ASP A C      1 
ATOM   2768 O O      . ASP B 2 104 ? 56.358 45.156  1.746  1.00 2.01  ? 104 ASP A O      1 
ATOM   2769 C CB     . ASP B 2 104 ? 57.354 42.855  -0.246 1.00 2.01  ? 104 ASP A CB     1 
ATOM   2770 C CG     . ASP B 2 104 ? 58.592 42.048  -0.567 1.00 2.00  ? 104 ASP A CG     1 
ATOM   2771 O OD1    . ASP B 2 104 ? 59.691 42.663  -0.602 1.00 2.01  ? 104 ASP A OD1    1 
ATOM   2772 O OD2    . ASP B 2 104 ? 58.446 40.813  -0.764 1.00 2.00  ? 104 ASP A OD2    1 
ATOM   2773 H H      . ASP B 2 104 ? 56.536 40.874  1.189  1.00 20.00 ? 104 ASP A H      1 
ATOM   2774 N N      . GLN B 2 105 ? 54.774 43.581  1.581  1.00 2.51  ? 105 GLN A N      1 
ATOM   2775 C CA     . GLN B 2 105 ? 53.603 44.431  1.858  1.00 2.01  ? 105 GLN A CA     1 
ATOM   2776 C C      . GLN B 2 105 ? 53.635 44.857  3.305  1.00 2.01  ? 105 GLN A C      1 
ATOM   2777 O O      . GLN B 2 105 ? 53.390 46.008  3.631  1.00 2.01  ? 105 GLN A O      1 
ATOM   2778 C CB     . GLN B 2 105 ? 52.370 43.577  1.722  1.00 2.01  ? 105 GLN A CB     1 
ATOM   2779 C CG     . GLN B 2 105 ? 51.312 44.256  1.037  1.00 2.00  ? 105 GLN A CG     1 
ATOM   2780 C CD     . GLN B 2 105 ? 51.559 44.257  -0.422 1.00 2.20  ? 105 GLN A CD     1 
ATOM   2781 O OE1    . GLN B 2 105 ? 51.519 43.186  -1.071 1.00 2.00  ? 105 GLN A OE1    1 
ATOM   2782 N NE2    . GLN B 2 105 ? 51.818 45.452  -0.978 1.00 4.66  ? 105 GLN A NE2    1 
ATOM   2783 H H      . GLN B 2 105 ? 54.604 42.616  1.389  1.00 20.00 ? 105 GLN A H      1 
ATOM   2784 H HE21   . GLN B 2 105 ? 51.942 45.456  -1.956 1.00 20.00 ? 105 GLN A HE21   1 
ATOM   2785 H HE22   . GLN B 2 105 ? 51.809 46.228  -0.428 1.00 20.00 ? 105 GLN A HE22   1 
ATOM   2786 N N      . LEU B 2 106 ? 53.844 43.876  4.172  1.00 2.00  ? 106 LEU A N      1 
ATOM   2787 C CA     . LEU B 2 106 ? 53.919 44.124  5.596  1.00 2.01  ? 106 LEU A CA     1 
ATOM   2788 C C      . LEU B 2 106 ? 55.025 45.157  5.851  1.00 2.01  ? 106 LEU A C      1 
ATOM   2789 O O      . LEU B 2 106 ? 54.789 46.184  6.456  1.00 2.00  ? 106 LEU A O      1 
ATOM   2790 C CB     . LEU B 2 106 ? 54.182 42.811  6.344  1.00 2.01  ? 106 LEU A CB     1 
ATOM   2791 C CG     . LEU B 2 106 ? 52.990 41.975  6.798  1.00 2.01  ? 106 LEU A CG     1 
ATOM   2792 C CD1    . LEU B 2 106 ? 51.741 42.489  6.256  1.00 2.01  ? 106 LEU A CD1    1 
ATOM   2793 C CD2    . LEU B 2 106 ? 53.167 40.550  6.407  1.00 2.01  ? 106 LEU A CD2    1 
ATOM   2794 H H      . LEU B 2 106 ? 53.923 42.954  3.843  1.00 20.00 ? 106 LEU A H      1 
ATOM   2795 N N      . HIS B 2 107 ? 56.216 44.919  5.334  1.00 2.01  ? 107 HIS A N      1 
ATOM   2796 C CA     . HIS B 2 107 ? 57.302 45.854  5.512  1.00 2.01  ? 107 HIS A CA     1 
ATOM   2797 C C      . HIS B 2 107 ? 56.929 47.274  5.013  1.00 3.49  ? 107 HIS A C      1 
ATOM   2798 O O      . HIS B 2 107 ? 57.287 48.293  5.634  1.00 2.01  ? 107 HIS A O      1 
ATOM   2799 C CB     . HIS B 2 107 ? 58.514 45.317  4.759  1.00 2.01  ? 107 HIS A CB     1 
ATOM   2800 C CG     . HIS B 2 107 ? 59.688 46.219  4.788  1.00 2.01  ? 107 HIS A CG     1 
ATOM   2801 N ND1    . HIS B 2 107 ? 60.039 46.991  3.702  1.00 2.01  ? 107 HIS A ND1    1 
ATOM   2802 C CD2    . HIS B 2 107 ? 60.571 46.520  5.766  1.00 2.00  ? 107 HIS A CD2    1 
ATOM   2803 C CE1    . HIS B 2 107 ? 61.088 47.738  4.016  1.00 2.00  ? 107 HIS A CE1    1 
ATOM   2804 N NE2    . HIS B 2 107 ? 61.428 47.465  5.265  1.00 2.00  ? 107 HIS A NE2    1 
ATOM   2805 H H      . HIS B 2 107 ? 56.351 44.075  4.813  1.00 20.00 ? 107 HIS A H      1 
ATOM   2806 H HD1    . HIS B 2 107 ? 59.607 46.984  2.816  1.00 20.00 ? 107 HIS A HD1    1 
ATOM   2807 H HE2    . HIS B 2 107 ? 62.185 47.878  5.749  1.00 20.00 ? 107 HIS A HE2    1 
ATOM   2808 N N      . ALA B 2 108 ? 56.182 47.332  3.906  1.00 2.00  ? 108 ALA A N      1 
ATOM   2809 C CA     . ALA B 2 108 ? 55.772 48.606  3.357  1.00 2.01  ? 108 ALA A CA     1 
ATOM   2810 C C      . ALA B 2 108 ? 54.849 49.296  4.329  1.00 2.00  ? 108 ALA A C      1 
ATOM   2811 O O      . ALA B 2 108 ? 54.943 50.489  4.499  1.00 2.00  ? 108 ALA A O      1 
ATOM   2812 C CB     . ALA B 2 108 ? 55.093 48.426  2.080  1.00 2.01  ? 108 ALA A CB     1 
ATOM   2813 H H      . ALA B 2 108 ? 55.902 46.509  3.449  1.00 20.00 ? 108 ALA A H      1 
ATOM   2814 N N      . TYR B 2 109 ? 53.973 48.543  4.982  1.00 2.00  ? 109 TYR A N      1 
ATOM   2815 C CA     . TYR B 2 109 ? 53.048 49.125  5.948  1.00 2.01  ? 109 TYR A CA     1 
ATOM   2816 C C      . TYR B 2 109 ? 53.724 49.530  7.233  1.00 2.00  ? 109 TYR A C      1 
ATOM   2817 O O      . TYR B 2 109 ? 53.203 50.400  7.940  1.00 2.00  ? 109 TYR A O      1 
ATOM   2818 C CB     . TYR B 2 109 ? 51.887 48.197  6.285  1.00 2.00  ? 109 TYR A CB     1 
ATOM   2819 C CG     . TYR B 2 109 ? 50.781 48.229  5.279  1.00 2.01  ? 109 TYR A CG     1 
ATOM   2820 C CD1    . TYR B 2 109 ? 50.200 49.435  4.902  1.00 2.01  ? 109 TYR A CD1    1 
ATOM   2821 C CD2    . TYR B 2 109 ? 50.336 47.066  4.677  1.00 2.01  ? 109 TYR A CD2    1 
ATOM   2822 C CE1    . TYR B 2 109 ? 49.209 49.494  3.955  1.00 2.01  ? 109 TYR A CE1    1 
ATOM   2823 C CE2    . TYR B 2 109 ? 49.342 47.119  3.727  1.00 2.01  ? 109 TYR A CE2    1 
ATOM   2824 C CZ     . TYR B 2 109 ? 48.795 48.336  3.383  1.00 2.01  ? 109 TYR A CZ     1 
ATOM   2825 O OH     . TYR B 2 109 ? 47.829 48.382  2.448  1.00 2.01  ? 109 TYR A OH     1 
ATOM   2826 H H      . TYR B 2 109 ? 53.964 47.587  4.811  1.00 20.00 ? 109 TYR A H      1 
ATOM   2827 H HH     . TYR B 2 109 ? 47.644 47.507  2.090  1.00 20.00 ? 109 TYR A HH     1 
ATOM   2828 N N      . ALA B 2 110 ? 54.821 48.850  7.592  1.00 2.01  ? 110 ALA A N      1 
ATOM   2829 C CA     . ALA B 2 110 ? 55.539 49.211  8.812  1.00 2.00  ? 110 ALA A CA     1 
ATOM   2830 C C      . ALA B 2 110 ? 56.091 50.605  8.563  1.00 2.00  ? 110 ALA A C      1 
ATOM   2831 O O      . ALA B 2 110 ? 56.005 51.472  9.430  1.00 2.01  ? 110 ALA A O      1 
ATOM   2832 C CB     . ALA B 2 110 ? 56.673 48.253  9.113  1.00 2.00  ? 110 ALA A CB     1 
ATOM   2833 H H      . ALA B 2 110 ? 55.132 48.089  7.039  1.00 20.00 ? 110 ALA A H      1 
ATOM   2834 N N      . ILE B 2 111 ? 56.564 50.850  7.338  1.00 2.14  ? 111 ILE A N      1 
ATOM   2835 C CA     . ILE B 2 111 ? 57.112 52.148  6.983  1.00 2.00  ? 111 ILE A CA     1 
ATOM   2836 C C      . ILE B 2 111 ? 56.054 53.227  7.059  1.00 2.01  ? 111 ILE A C      1 
ATOM   2837 O O      . ILE B 2 111 ? 56.327 54.283  7.589  1.00 2.01  ? 111 ILE A O      1 
ATOM   2838 C CB     . ILE B 2 111 ? 57.814 52.122  5.635  1.00 2.01  ? 111 ILE A CB     1 
ATOM   2839 C CG1    . ILE B 2 111 ? 59.152 51.436  5.800  1.00 2.01  ? 111 ILE A CG1    1 
ATOM   2840 C CG2    . ILE B 2 111 ? 58.084 53.490  5.142  1.00 2.00  ? 111 ILE A CG2    1 
ATOM   2841 C CD1    . ILE B 2 111 ? 59.942 51.356  4.533  1.00 2.01  ? 111 ILE A CD1    1 
ATOM   2842 H H      . ILE B 2 111 ? 56.560 50.133  6.654  1.00 20.00 ? 111 ILE A H      1 
ATOM   2843 N N      . GLU B 2 112 ? 54.839 52.970  6.598  1.00 2.01  ? 112 GLU A N      1 
ATOM   2844 C CA     . GLU B 2 112 ? 53.783 53.980  6.698  1.00 2.01  ? 112 GLU A CA     1 
ATOM   2845 C C      . GLU B 2 112 ? 53.599 54.326  8.160  1.00 2.01  ? 112 GLU A C      1 
ATOM   2846 O O      . GLU B 2 112 ? 53.567 55.493  8.534  1.00 3.03  ? 112 GLU A O      1 
ATOM   2847 C CB     . GLU B 2 112 ? 52.467 53.462  6.147  1.00 2.01  ? 112 GLU A CB     1 
ATOM   2848 C CG     . GLU B 2 112 ? 51.337 54.453  6.246  1.00 2.01  ? 112 GLU A CG     1 
ATOM   2849 C CD     . GLU B 2 112 ? 50.067 53.924  5.634  1.00 2.00  ? 112 GLU A CD     1 
ATOM   2850 O OE1    . GLU B 2 112 ? 49.987 52.709  5.434  1.00 2.01  ? 112 GLU A OE1    1 
ATOM   2851 O OE2    . GLU B 2 112 ? 49.139 54.708  5.359  1.00 2.01  ? 112 GLU A OE2    1 
ATOM   2852 H H      . GLU B 2 112 ? 54.659 52.101  6.181  1.00 20.00 ? 112 GLU A H      1 
ATOM   2853 N N      . LEU B 2 113 ? 53.528 53.301  9.004  1.00 2.67  ? 113 LEU A N      1 
ATOM   2854 C CA     . LEU B 2 113 ? 53.392 53.510  10.439 1.00 2.01  ? 113 LEU A CA     1 
ATOM   2855 C C      . LEU B 2 113 ? 54.535 54.397  10.918 1.00 2.01  ? 113 LEU A C      1 
ATOM   2856 O O      . LEU B 2 113 ? 54.292 55.384  11.590 1.00 2.01  ? 113 LEU A O      1 
ATOM   2857 C CB     . LEU B 2 113 ? 53.371 52.169  11.178 1.00 2.01  ? 113 LEU A CB     1 
ATOM   2858 C CG     . LEU B 2 113 ? 52.011 51.779  11.749 1.00 2.01  ? 113 LEU A CG     1 
ATOM   2859 C CD1    . LEU B 2 113 ? 50.903 52.476  11.008 1.00 2.01  ? 113 LEU A CD1    1 
ATOM   2860 C CD2    . LEU B 2 113 ? 51.850 50.298  11.700 1.00 2.01  ? 113 LEU A CD2    1 
ATOM   2861 H H      . LEU B 2 113 ? 53.532 52.380  8.660  1.00 20.00 ? 113 LEU A H      1 
ATOM   2862 N N      . ILE B 2 114 ? 55.765 54.100  10.514 1.00 2.01  ? 114 ILE A N      1 
ATOM   2863 C CA     . ILE B 2 114 ? 56.909 54.899  10.933 1.00 2.01  ? 114 ILE A CA     1 
ATOM   2864 C C      . ILE B 2 114 ? 56.750 56.327  10.432 1.00 2.00  ? 114 ILE A C      1 
ATOM   2865 O O      . ILE B 2 114 ? 56.846 57.274  11.203 1.00 2.01  ? 114 ILE A O      1 
ATOM   2866 C CB     . ILE B 2 114 ? 58.255 54.297  10.451 1.00 2.01  ? 114 ILE A CB     1 
ATOM   2867 C CG1    . ILE B 2 114 ? 58.559 52.989  11.186 1.00 2.02  ? 114 ILE A CG1    1 
ATOM   2868 C CG2    . ILE B 2 114 ? 59.367 55.289  10.685 1.00 2.01  ? 114 ILE A CG2    1 
ATOM   2869 C CD1    . ILE B 2 114 ? 59.809 52.301  10.704 1.00 2.01  ? 114 ILE A CD1    1 
ATOM   2870 H H      . ILE B 2 114 ? 55.911 53.293  9.978  1.00 20.00 ? 114 ILE A H      1 
ATOM   2871 N N      . ASN B 2 115 ? 56.430 56.475  9.156  1.00 3.51  ? 115 ASN A N      1 
ATOM   2872 C CA     . ASN B 2 115 ? 56.259 57.798  8.568  1.00 3.96  ? 115 ASN A CA     1 
ATOM   2873 C C      . ASN B 2 115 ? 55.246 58.658  9.313  1.00 2.43  ? 115 ASN A C      1 
ATOM   2874 O O      . ASN B 2 115 ? 55.363 59.873  9.295  1.00 4.07  ? 115 ASN A O      1 
ATOM   2875 C CB     . ASN B 2 115 ? 55.875 57.722  7.088  1.00 7.04  ? 115 ASN A CB     1 
ATOM   2876 C CG     . ASN B 2 115 ? 57.058 57.433  6.195  1.00 12.80 ? 115 ASN A CG     1 
ATOM   2877 O OD1    . ASN B 2 115 ? 58.173 57.842  6.498  1.00 15.36 ? 115 ASN A OD1    1 
ATOM   2878 N ND2    . ASN B 2 115 ? 56.826 56.754  5.068  1.00 14.48 ? 115 ASN A ND2    1 
ATOM   2879 H H      . ASN B 2 115 ? 56.357 55.710  8.604  1.00 20.00 ? 115 ASN A H      1 
ATOM   2880 H HD21   . ASN B 2 115 ? 57.576 56.572  4.479  1.00 20.00 ? 115 ASN A HD21   1 
ATOM   2881 H HD22   . ASN B 2 115 ? 55.901 56.481  4.866  1.00 20.00 ? 115 ASN A HD22   1 
ATOM   2882 N N      . LYS B 2 116 ? 54.240 58.050  9.936  1.00 2.01  ? 116 LYS A N      1 
ATOM   2883 C CA     . LYS B 2 116 ? 53.231 58.793  10.687 1.00 2.00  ? 116 LYS A CA     1 
ATOM   2884 C C      . LYS B 2 116 ? 53.563 58.885  12.171 1.00 2.00  ? 116 LYS A C      1 
ATOM   2885 O O      . LYS B 2 116 ? 52.712 59.278  12.981 1.00 2.01  ? 116 LYS A O      1 
ATOM   2886 C CB     . LYS B 2 116 ? 51.899 58.072  10.622 1.00 2.00  ? 116 LYS A CB     1 
ATOM   2887 C CG     . LYS B 2 116 ? 51.244 58.014  9.285  1.00 5.58  ? 116 LYS A CG     1 
ATOM   2888 C CD     . LYS B 2 116 ? 49.920 57.302  9.495  1.00 6.24  ? 116 LYS A CD     1 
ATOM   2889 C CE     . LYS B 2 116 ? 49.114 57.214  8.253  1.00 5.95  ? 116 LYS A CE     1 
ATOM   2890 N NZ     . LYS B 2 116 ? 47.839 56.525  8.614  1.00 7.56  ? 116 LYS A NZ     1 
ATOM   2891 H H      . LYS B 2 116 ? 54.196 57.059  9.905  1.00 20.00 ? 116 LYS A H      1 
ATOM   2892 H HZ1    . LYS B 2 116 ? 47.469 56.924  9.482  1.00 20.00 ? 116 LYS A HZ1    1 
ATOM   2893 H HZ2    . LYS B 2 116 ? 47.177 56.625  7.830  1.00 20.00 ? 116 LYS A HZ2    1 
ATOM   2894 H HZ3    . LYS B 2 116 ? 48.033 55.496  8.759  1.00 20.00 ? 116 LYS A HZ3    1 
ATOM   2895 N N      . GLY B 2 117 ? 54.762 58.458  12.549 1.00 2.01  ? 117 GLY A N      1 
ATOM   2896 C CA     . GLY B 2 117 ? 55.154 58.498  13.940 1.00 2.01  ? 117 GLY A CA     1 
ATOM   2897 C C      . GLY B 2 117 ? 54.418 57.524  14.851 1.00 2.00  ? 117 GLY A C      1 
ATOM   2898 O O      . GLY B 2 117 ? 54.498 57.672  16.080 1.00 2.00  ? 117 GLY A O      1 
ATOM   2899 H H      . GLY B 2 117 ? 55.337 58.016  11.883 1.00 20.00 ? 117 GLY A H      1 
ATOM   2900 N N      . LEU B 2 118 ? 53.748 56.517  14.284 1.00 2.00  ? 118 LEU A N      1 
ATOM   2901 C CA     . LEU B 2 118 ? 53.026 55.518  15.073 1.00 2.01  ? 118 LEU A CA     1 
ATOM   2902 C C      . LEU B 2 118 ? 53.847 54.250  15.312 1.00 2.00  ? 118 LEU A C      1 
ATOM   2903 O O      . LEU B 2 118 ? 53.280 53.200  15.614 1.00 2.01  ? 118 LEU A O      1 
ATOM   2904 C CB     . LEU B 2 118 ? 51.723 55.156  14.384 1.00 2.01  ? 118 LEU A CB     1 
ATOM   2905 C CG     . LEU B 2 118 ? 50.733 56.305  14.357 1.00 2.01  ? 118 LEU A CG     1 
ATOM   2906 C CD1    . LEU B 2 118 ? 49.561 55.990  13.444 1.00 2.00  ? 118 LEU A CD1    1 
ATOM   2907 C CD2    . LEU B 2 118 ? 50.255 56.576  15.738 1.00 2.01  ? 118 LEU A CD2    1 
ATOM   2908 H H      . LEU B 2 118 ? 53.775 56.407  13.307 1.00 20.00 ? 118 LEU A H      1 
ATOM   2909 N N      . ALA B 2 119 ? 55.163 54.340  15.150 1.00 2.02  ? 119 ALA A N      1 
ATOM   2910 C CA     . ALA B 2 119 ? 56.061 53.202  15.347 1.00 2.01  ? 119 ALA A CA     1 
ATOM   2911 C C      . ALA B 2 119 ? 57.506 53.700  15.500 1.00 2.00  ? 119 ALA A C      1 
ATOM   2912 O O      . ALA B 2 119 ? 57.882 54.751  14.964 1.00 2.00  ? 119 ALA A O      1 
ATOM   2913 C CB     . ALA B 2 119 ? 55.953 52.241  14.190 1.00 2.01  ? 119 ALA A CB     1 
ATOM   2914 H H      . ALA B 2 119 ? 55.567 55.188  14.869 1.00 20.00 ? 119 ALA A H      1 
ATOM   2915 N N      . TYR B 2 120 ? 58.331 52.935  16.198 1.00 2.01  ? 120 TYR A N      1 
ATOM   2916 C CA     . TYR B 2 120 ? 59.699 53.372  16.404 1.00 2.01  ? 120 TYR A CA     1 
ATOM   2917 C C      . TYR B 2 120 ? 60.577 52.183  16.681 1.00 2.00  ? 120 TYR A C      1 
ATOM   2918 O O      . TYR B 2 120 ? 60.082 51.135  17.098 1.00 2.00  ? 120 TYR A O      1 
ATOM   2919 C CB     . TYR B 2 120 ? 59.735 54.297  17.607 1.00 2.01  ? 120 TYR A CB     1 
ATOM   2920 C CG     . TYR B 2 120 ? 59.341 53.626  18.920 1.00 2.01  ? 120 TYR A CG     1 
ATOM   2921 C CD1    . TYR B 2 120 ? 58.014 53.539  19.294 1.00 2.01  ? 120 TYR A CD1    1 
ATOM   2922 C CD2    . TYR B 2 120 ? 60.302 53.126  19.805 1.00 2.01  ? 120 TYR A CD2    1 
ATOM   2923 C CE1    . TYR B 2 120 ? 57.649 52.987  20.503 1.00 2.00  ? 120 TYR A CE1    1 
ATOM   2924 C CE2    . TYR B 2 120 ? 59.940 52.567  21.015 1.00 2.01  ? 120 TYR A CE2    1 
ATOM   2925 C CZ     . TYR B 2 120 ? 58.616 52.502  21.365 1.00 2.01  ? 120 TYR A CZ     1 
ATOM   2926 O OH     . TYR B 2 120 ? 58.235 51.995  22.590 1.00 2.01  ? 120 TYR A OH     1 
ATOM   2927 H H      . TYR B 2 120 ? 58.018 52.099  16.592 1.00 20.00 ? 120 TYR A H      1 
ATOM   2928 H HH     . TYR B 2 120 ? 59.028 51.688  23.044 1.00 20.00 ? 120 TYR A HH     1 
ATOM   2929 N N      . VAL B 2 121 ? 61.874 52.307  16.425 1.00 2.01  ? 121 VAL A N      1 
ATOM   2930 C CA     . VAL B 2 121 ? 62.807 51.217  16.702 1.00 2.01  ? 121 VAL A CA     1 
ATOM   2931 C C      . VAL B 2 121 ? 63.263 51.385  18.144 1.00 2.00  ? 121 VAL A C      1 
ATOM   2932 O O      . VAL B 2 121 ? 63.921 52.371  18.501 1.00 2.01  ? 121 VAL A O      1 
ATOM   2933 C CB     . VAL B 2 121 ? 64.052 51.269  15.803 1.00 2.01  ? 121 VAL A CB     1 
ATOM   2934 C CG1    . VAL B 2 121 ? 65.087 50.232  16.256 1.00 2.01  ? 121 VAL A CG1    1 
ATOM   2935 C CG2    . VAL B 2 121 ? 63.679 51.072  14.367 1.00 2.01  ? 121 VAL A CG2    1 
ATOM   2936 H H      . VAL B 2 121 ? 62.226 53.156  16.101 1.00 20.00 ? 121 VAL A H      1 
ATOM   2937 N N      . ASP B 2 122 ? 62.874 50.440  18.978 1.00 2.01  ? 122 ASP A N      1 
ATOM   2938 C CA     . ASP B 2 122 ? 63.238 50.495  20.362 1.00 2.01  ? 122 ASP A CA     1 
ATOM   2939 C C      . ASP B 2 122 ? 64.476 49.658  20.540 1.00 2.00  ? 122 ASP A C      1 
ATOM   2940 O O      . ASP B 2 122 ? 64.698 48.724  19.786 1.00 2.00  ? 122 ASP A O      1 
ATOM   2941 C CB     . ASP B 2 122 ? 62.102 49.948  21.211 1.00 2.01  ? 122 ASP A CB     1 
ATOM   2942 C CG     . ASP B 2 122 ? 62.258 50.284  22.674 1.00 2.00  ? 122 ASP A CG     1 
ATOM   2943 O OD1    . ASP B 2 122 ? 63.313 50.870  23.042 1.00 2.01  ? 122 ASP A OD1    1 
ATOM   2944 O OD2    . ASP B 2 122 ? 61.329 49.939  23.452 1.00 2.01  ? 122 ASP A OD2    1 
ATOM   2945 H H      . ASP B 2 122 ? 62.369 49.665  18.636 1.00 20.00 ? 122 ASP A H      1 
ATOM   2946 N N      . GLU B 2 123 ? 65.259 49.967  21.569 1.00 2.00  ? 123 GLU A N      1 
ATOM   2947 C CA     . GLU B 2 123 ? 66.484 49.229  21.830 1.00 2.01  ? 123 GLU A CA     1 
ATOM   2948 C C      . GLU B 2 123 ? 66.551 48.589  23.223 1.00 2.00  ? 123 GLU A C      1 
ATOM   2949 O O      . GLU B 2 123 ? 67.584 48.056  23.635 1.00 2.01  ? 123 GLU A O      1 
ATOM   2950 C CB     . GLU B 2 123 ? 67.710 50.100  21.564 1.00 2.01  ? 123 GLU A CB     1 
ATOM   2951 C CG     . GLU B 2 123 ? 67.945 50.327  20.108 1.00 2.00  ? 123 GLU A CG     1 
ATOM   2952 C CD     . GLU B 2 123 ? 69.300 50.876  19.841 1.00 2.00  ? 123 GLU A CD     1 
ATOM   2953 O OE1    . GLU B 2 123 ? 70.289 50.170  20.117 1.00 2.30  ? 123 GLU A OE1    1 
ATOM   2954 O OE2    . GLU B 2 123 ? 69.367 52.018  19.363 1.00 3.76  ? 123 GLU A OE2    1 
ATOM   2955 H H      . GLU B 2 123 ? 65.049 50.729  22.125 1.00 20.00 ? 123 GLU A H      1 
ATOM   2956 N N      . LEU B 2 124 ? 65.462 48.668  23.964 1.00 2.00  ? 124 LEU A N      1 
ATOM   2957 C CA     . LEU B 2 124 ? 65.417 48.065  25.289 1.00 2.00  ? 124 LEU A CA     1 
ATOM   2958 C C      . LEU B 2 124 ? 65.716 46.563  25.094 1.00 2.01  ? 124 LEU A C      1 
ATOM   2959 O O      . LEU B 2 124 ? 65.244 45.951  24.132 1.00 2.00  ? 124 LEU A O      1 
ATOM   2960 C CB     . LEU B 2 124 ? 64.007 48.252  25.845 1.00 2.41  ? 124 LEU A CB     1 
ATOM   2961 C CG     . LEU B 2 124 ? 63.760 48.984  27.156 1.00 2.01  ? 124 LEU A CG     1 
ATOM   2962 C CD1    . LEU B 2 124 ? 64.490 50.290  27.170 1.00 2.00  ? 124 LEU A CD1    1 
ATOM   2963 C CD2    . LEU B 2 124 ? 62.296 49.230  27.322 1.00 2.01  ? 124 LEU A CD2    1 
ATOM   2964 H H      . LEU B 2 124 ? 64.664 49.062  23.589 1.00 20.00 ? 124 LEU A H      1 
ATOM   2965 N N      . THR B 2 125 ? 66.485 45.950  25.973 1.00 2.01  ? 125 THR A N      1 
ATOM   2966 C CA     . THR B 2 125 ? 66.751 44.525  25.785 1.00 2.00  ? 125 THR A CA     1 
ATOM   2967 C C      . THR B 2 125 ? 65.472 43.700  25.985 1.00 2.00  ? 125 THR A C      1 
ATOM   2968 O O      . THR B 2 125 ? 64.410 44.256  26.303 1.00 2.01  ? 125 THR A O      1 
ATOM   2969 C CB     . THR B 2 125 ? 67.783 44.012  26.787 1.00 2.01  ? 125 THR A CB     1 
ATOM   2970 O OG1    . THR B 2 125 ? 67.209 44.074  28.094 1.00 2.01  ? 125 THR A OG1    1 
ATOM   2971 C CG2    . THR B 2 125 ? 69.024 44.861  26.775 1.00 2.00  ? 125 THR A CG2    1 
ATOM   2972 H H      . THR B 2 125 ? 66.899 46.444  26.684 1.00 20.00 ? 125 THR A H      1 
ATOM   2973 H HG1    . THR B 2 125 ? 67.845 43.751  28.743 1.00 20.00 ? 125 THR A HG1    1 
ATOM   2974 N N      . PRO B 2 126 ? 65.559 42.365  25.851 1.00 2.04  ? 126 PRO A N      1 
ATOM   2975 C CA     . PRO B 2 126 ? 64.347 41.586  26.047 1.00 2.33  ? 126 PRO A CA     1 
ATOM   2976 C C      . PRO B 2 126 ? 63.896 41.583  27.498 1.00 5.37  ? 126 PRO A C      1 
ATOM   2977 O O      . PRO B 2 126 ? 62.700 41.665  27.785 1.00 4.65  ? 126 PRO A O      1 
ATOM   2978 C CB     . PRO B 2 126 ? 64.775 40.205  25.581 1.00 2.00  ? 126 PRO A CB     1 
ATOM   2979 C CG     . PRO B 2 126 ? 65.538 40.539  24.408 1.00 2.01  ? 126 PRO A CG     1 
ATOM   2980 C CD     . PRO B 2 126 ? 66.455 41.629  24.953 1.00 2.00  ? 126 PRO A CD     1 
ATOM   2981 N N      . GLU B 2 127 ? 64.846 41.541  28.416 1.00 9.01  ? 127 GLU A N      1 
ATOM   2982 C CA     . GLU B 2 127 ? 64.478 41.558  29.812 1.00 15.70 ? 127 GLU A CA     1 
ATOM   2983 C C      . GLU B 2 127 ? 63.853 42.909  30.175 1.00 15.72 ? 127 GLU A C      1 
ATOM   2984 O O      . GLU B 2 127 ? 62.820 42.967  30.849 1.00 11.97 ? 127 GLU A O      1 
ATOM   2985 C CB     . GLU B 2 127 ? 65.702 41.312  30.686 1.00 24.17 ? 127 GLU A CB     1 
ATOM   2986 C CG     . GLU B 2 127 ? 66.364 39.977  30.454 1.00 33.49 ? 127 GLU A CG     1 
ATOM   2987 C CD     . GLU B 2 127 ? 66.836 39.764  29.011 1.00 38.61 ? 127 GLU A CD     1 
ATOM   2988 O OE1    . GLU B 2 127 ? 67.770 40.467  28.548 1.00 42.26 ? 127 GLU A OE1    1 
ATOM   2989 O OE2    . GLU B 2 127 ? 66.259 38.881  28.335 1.00 39.93 ? 127 GLU A OE2    1 
ATOM   2990 H H      . GLU B 2 127 ? 65.768 41.558  28.141 1.00 20.00 ? 127 GLU A H      1 
ATOM   2991 N N      . GLN B 2 128 ? 64.463 43.988  29.681 1.00 15.00 ? 128 GLN A N      1 
ATOM   2992 C CA     . GLN B 2 128 ? 63.999 45.356  29.941 1.00 14.95 ? 128 GLN A CA     1 
ATOM   2993 C C      . GLN B 2 128 ? 62.622 45.618  29.379 1.00 15.07 ? 128 GLN A C      1 
ATOM   2994 O O      . GLN B 2 128 ? 61.783 46.187  30.078 1.00 16.47 ? 128 GLN A O      1 
ATOM   2995 C CB     . GLN B 2 128 ? 64.973 46.388  29.370 1.00 16.60 ? 128 GLN A CB     1 
ATOM   2996 C CG     . GLN B 2 128 ? 66.257 46.587  30.171 1.00 15.88 ? 128 GLN A CG     1 
ATOM   2997 C CD     . GLN B 2 128 ? 67.379 47.308  29.393 1.00 17.60 ? 128 GLN A CD     1 
ATOM   2998 O OE1    . GLN B 2 128 ? 67.345 47.431  28.159 1.00 15.94 ? 128 GLN A OE1    1 
ATOM   2999 N NE2    . GLN B 2 128 ? 68.397 47.759  30.121 1.00 17.01 ? 128 GLN A NE2    1 
ATOM   3000 H H      . GLN B 2 128 ? 65.240 43.856  29.113 1.00 20.00 ? 128 GLN A H      1 
ATOM   3001 H HE21   . GLN B 2 128 ? 69.126 48.194  29.644 1.00 20.00 ? 128 GLN A HE21   1 
ATOM   3002 H HE22   . GLN B 2 128 ? 68.394 47.622  31.086 1.00 20.00 ? 128 GLN A HE22   1 
ATOM   3003 N N      . THR B 2 129 ? 62.393 45.250  28.118 1.00 11.20 ? 129 THR A N      1 
ATOM   3004 C CA     . THR B 2 129 ? 61.077 45.454  27.508 1.00 12.04 ? 129 THR A CA     1 
ATOM   3005 C C      . THR B 2 129 ? 59.988 44.906  28.456 1.00 11.72 ? 129 THR A C      1 
ATOM   3006 O O      . THR B 2 129 ? 58.981 45.578  28.713 1.00 13.23 ? 129 THR A O      1 
ATOM   3007 C CB     . THR B 2 129 ? 60.944 44.753  26.123 1.00 12.19 ? 129 THR A CB     1 
ATOM   3008 O OG1    . THR B 2 129 ? 61.279 43.372  26.265 1.00 12.97 ? 129 THR A OG1    1 
ATOM   3009 C CG2    . THR B 2 129 ? 61.894 45.323  25.104 1.00 13.71 ? 129 THR A CG2    1 
ATOM   3010 H H      . THR B 2 129 ? 63.091 44.808  27.600 1.00 20.00 ? 129 THR A H      1 
ATOM   3011 H HG1    . THR B 2 129 ? 61.142 42.911  25.440 1.00 20.00 ? 129 THR A HG1    1 
ATOM   3012 N N      . ARG B 2 130 ? 60.237 43.729  29.038 1.00 13.82 ? 130 ARG A N      1 
ATOM   3013 C CA     . ARG B 2 130 ? 59.297 43.095  29.949 1.00 14.26 ? 130 ARG A CA     1 
ATOM   3014 C C      . ARG B 2 130 ? 59.088 43.968  31.165 1.00 11.69 ? 130 ARG A C      1 
ATOM   3015 O O      . ARG B 2 130 ? 57.960 44.210  31.578 1.00 10.62 ? 130 ARG A O      1 
ATOM   3016 C CB     . ARG B 2 130 ? 59.817 41.736  30.370 1.00 18.55 ? 130 ARG A CB     1 
ATOM   3017 C CG     . ARG B 2 130 ? 58.831 40.922  31.194 1.00 25.85 ? 130 ARG A CG     1 
ATOM   3018 C CD     . ARG B 2 130 ? 59.495 39.702  31.844 1.00 34.20 ? 130 ARG A CD     1 
ATOM   3019 N NE     . ARG B 2 130 ? 60.657 40.093  32.652 1.00 42.46 ? 130 ARG A NE     1 
ATOM   3020 C CZ     . ARG B 2 130 ? 61.904 39.668  32.439 1.00 43.27 ? 130 ARG A CZ     1 
ATOM   3021 N NH1    . ARG B 2 130 ? 62.155 38.795  31.467 1.00 46.34 ? 130 ARG A NH1    1 
ATOM   3022 N NH2    . ARG B 2 130 ? 62.895 40.092  33.214 1.00 46.57 ? 130 ARG A NH2    1 
ATOM   3023 H H      . ARG B 2 130 ? 61.078 43.281  28.843 1.00 20.00 ? 130 ARG A H      1 
ATOM   3024 H HE     . ARG B 2 130 ? 60.494 40.685  33.425 1.00 20.00 ? 130 ARG A HE     1 
ATOM   3025 H HH11   . ARG B 2 130 ? 61.394 38.466  30.894 1.00 20.00 ? 130 ARG A HH11   1 
ATOM   3026 H HH12   . ARG B 2 130 ? 63.080 38.501  31.285 1.00 20.00 ? 130 ARG A HH12   1 
ATOM   3027 H HH21   . ARG B 2 130 ? 62.703 40.718  33.972 1.00 20.00 ? 130 ARG A HH21   1 
ATOM   3028 H HH22   . ARG B 2 130 ? 63.825 39.784  33.037 1.00 20.00 ? 130 ARG A HH22   1 
ATOM   3029 N N      . GLU B 2 131 ? 60.183 44.483  31.707 1.00 11.29 ? 131 GLU A N      1 
ATOM   3030 C CA     . GLU B 2 131 ? 60.133 45.332  32.886 1.00 13.09 ? 131 GLU A CA     1 
ATOM   3031 C C      . GLU B 2 131 ? 59.327 46.608  32.696 1.00 8.84  ? 131 GLU A C      1 
ATOM   3032 O O      . GLU B 2 131 ? 58.533 46.964  33.568 1.00 10.81 ? 131 GLU A O      1 
ATOM   3033 C CB     . GLU B 2 131 ? 61.534 45.699  33.345 1.00 24.44 ? 131 GLU A CB     1 
ATOM   3034 C CG     . GLU B 2 131 ? 62.351 44.509  33.840 1.00 33.35 ? 131 GLU A CG     1 
ATOM   3035 C CD     . GLU B 2 131 ? 63.659 44.924  34.496 1.00 43.79 ? 131 GLU A CD     1 
ATOM   3036 O OE1    . GLU B 2 131 ? 64.055 46.112  34.358 1.00 42.30 ? 131 GLU A OE1    1 
ATOM   3037 O OE2    . GLU B 2 131 ? 64.286 44.060  35.151 1.00 46.56 ? 131 GLU A OE2    1 
ATOM   3038 H H      . GLU B 2 131 ? 61.052 44.323  31.273 1.00 20.00 ? 131 GLU A H      1 
ATOM   3039 N N      . TYR B 2 132 ? 59.524 47.305  31.577 1.00 5.60  ? 132 TYR A N      1 
ATOM   3040 C CA     . TYR B 2 132 ? 58.800 48.545  31.325 1.00 2.00  ? 132 TYR A CA     1 
ATOM   3041 C C      . TYR B 2 132 ? 57.323 48.353  31.011 1.00 2.00  ? 132 TYR A C      1 
ATOM   3042 O O      . TYR B 2 132 ? 56.542 49.302  31.116 1.00 2.00  ? 132 TYR A O      1 
ATOM   3043 C CB     . TYR B 2 132 ? 59.418 49.313  30.167 1.00 2.00  ? 132 TYR A CB     1 
ATOM   3044 C CG     . TYR B 2 132 ? 60.687 50.060  30.464 1.00 2.01  ? 132 TYR A CG     1 
ATOM   3045 C CD1    . TYR B 2 132 ? 61.823 49.420  30.954 1.00 2.01  ? 132 TYR A CD1    1 
ATOM   3046 C CD2    . TYR B 2 132 ? 60.759 51.421  30.226 1.00 2.00  ? 132 TYR A CD2    1 
ATOM   3047 C CE1    . TYR B 2 132 ? 63.007 50.126  31.195 1.00 2.01  ? 132 TYR A CE1    1 
ATOM   3048 C CE2    . TYR B 2 132 ? 61.940 52.141  30.468 1.00 2.00  ? 132 TYR A CE2    1 
ATOM   3049 C CZ     . TYR B 2 132 ? 63.060 51.496  30.946 1.00 2.01  ? 132 TYR A CZ     1 
ATOM   3050 O OH     . TYR B 2 132 ? 64.204 52.241  31.120 1.00 2.01  ? 132 TYR A OH     1 
ATOM   3051 H H      . TYR B 2 132 ? 60.131 46.961  30.890 1.00 20.00 ? 132 TYR A H      1 
ATOM   3052 H HH     . TYR B 2 132 ? 64.902 51.636  31.452 1.00 20.00 ? 132 TYR A HH     1 
ATOM   3053 N N      . ARG B 2 133 ? 56.924 47.130  30.675 1.00 2.00  ? 133 ARG A N      1 
ATOM   3054 C CA     . ARG B 2 133 ? 55.548 46.826  30.283 1.00 2.01  ? 133 ARG A CA     1 
ATOM   3055 C C      . ARG B 2 133 ? 54.456 46.907  31.367 1.00 2.00  ? 133 ARG A C      1 
ATOM   3056 O O      . ARG B 2 133 ? 53.255 46.934  31.075 1.00 2.01  ? 133 ARG A O      1 
ATOM   3057 C CB     . ARG B 2 133 ? 55.549 45.479  29.541 1.00 2.00  ? 133 ARG A CB     1 
ATOM   3058 C CG     . ARG B 2 133 ? 54.215 45.025  29.040 1.00 2.00  ? 133 ARG A CG     1 
ATOM   3059 C CD     . ARG B 2 133 ? 54.385 44.093  27.880 1.00 2.49  ? 133 ARG A CD     1 
ATOM   3060 N NE     . ARG B 2 133 ? 55.153 42.899  28.209 1.00 3.31  ? 133 ARG A NE     1 
ATOM   3061 C CZ     . ARG B 2 133 ? 56.057 42.367  27.388 1.00 5.33  ? 133 ARG A CZ     1 
ATOM   3062 N NH1    . ARG B 2 133 ? 56.287 42.956  26.223 1.00 5.76  ? 133 ARG A NH1    1 
ATOM   3063 N NH2    . ARG B 2 133 ? 56.735 41.267  27.720 1.00 5.71  ? 133 ARG A NH2    1 
ATOM   3064 H H      . ARG B 2 133 ? 57.573 46.392  30.711 1.00 20.00 ? 133 ARG A H      1 
ATOM   3065 H HE     . ARG B 2 133 ? 55.006 42.469  29.084 1.00 20.00 ? 133 ARG A HE     1 
ATOM   3066 H HH11   . ARG B 2 133 ? 55.753 43.762  25.956 1.00 20.00 ? 133 ARG A HH11   1 
ATOM   3067 H HH12   . ARG B 2 133 ? 56.939 42.556  25.588 1.00 20.00 ? 133 ARG A HH12   1 
ATOM   3068 H HH21   . ARG B 2 133 ? 56.579 40.860  28.627 1.00 20.00 ? 133 ARG A HH21   1 
ATOM   3069 H HH22   . ARG B 2 133 ? 57.414 40.899  27.106 1.00 20.00 ? 133 ARG A HH22   1 
ATOM   3070 N N      . GLY B 2 134 ? 54.871 47.037  32.616 1.00 3.67  ? 134 GLY A N      1 
ATOM   3071 C CA     . GLY B 2 134 ? 53.909 47.101  33.706 1.00 4.88  ? 134 GLY A CA     1 
ATOM   3072 C C      . GLY B 2 134 ? 53.450 45.688  33.984 1.00 6.55  ? 134 GLY A C      1 
ATOM   3073 O O      . GLY B 2 134 ? 54.030 44.751  33.446 1.00 7.65  ? 134 GLY A O      1 
ATOM   3074 H H      . GLY B 2 134 ? 55.819 47.078  32.809 1.00 20.00 ? 134 GLY A H      1 
ATOM   3075 N N      . THR B 2 135 ? 52.446 45.527  34.836 1.00 7.53  ? 135 THR A N      1 
ATOM   3076 C CA     . THR B 2 135 ? 51.920 44.216  35.193 1.00 11.94 ? 135 THR A CA     1 
ATOM   3077 C C      . THR B 2 135 ? 50.429 44.252  34.907 1.00 12.93 ? 135 THR A C      1 
ATOM   3078 O O      . THR B 2 135 ? 49.976 45.132  34.202 1.00 15.30 ? 135 THR A O      1 
ATOM   3079 C CB     . THR B 2 135 ? 52.130 43.967  36.670 1.00 14.29 ? 135 THR A CB     1 
ATOM   3080 O OG1    . THR B 2 135 ? 51.618 45.093  37.388 1.00 13.46 ? 135 THR A OG1    1 
ATOM   3081 C CG2    . THR B 2 135 ? 53.607 43.866  36.980 1.00 16.46 ? 135 THR A CG2    1 
ATOM   3082 H H      . THR B 2 135 ? 51.979 46.324  35.172 1.00 20.00 ? 135 THR A H      1 
ATOM   3083 H HG1    . THR B 2 135 ? 51.735 44.965  38.337 1.00 20.00 ? 135 THR A HG1    1 
ATOM   3084 N N      . LEU B 2 136 ? 49.647 43.344  35.471 1.00 16.60 ? 136 LEU A N      1 
ATOM   3085 C CA     . LEU B 2 136 ? 48.210 43.360  35.219 1.00 18.24 ? 136 LEU A CA     1 
ATOM   3086 C C      . LEU B 2 136 ? 47.450 44.403  36.034 1.00 21.24 ? 136 LEU A C      1 
ATOM   3087 O O      . LEU B 2 136 ? 46.241 44.543  35.876 1.00 20.55 ? 136 LEU A O      1 
ATOM   3088 C CB     . LEU B 2 136 ? 47.595 41.993  35.493 1.00 14.80 ? 136 LEU A CB     1 
ATOM   3089 C CG     . LEU B 2 136 ? 48.271 40.795  34.828 1.00 12.92 ? 136 LEU A CG     1 
ATOM   3090 C CD1    . LEU B 2 136 ? 47.465 39.529  35.066 1.00 13.24 ? 136 LEU A CD1    1 
ATOM   3091 C CD2    . LEU B 2 136 ? 48.404 41.049  33.346 1.00 11.07 ? 136 LEU A CD2    1 
ATOM   3092 H H      . LEU B 2 136 ? 50.018 42.671  36.056 1.00 20.00 ? 136 LEU A H      1 
ATOM   3093 N N      . THR B 2 137 ? 48.153 45.134  36.892 1.00 22.06 ? 137 THR A N      1 
ATOM   3094 C CA     . THR B 2 137 ? 47.527 46.133  37.745 1.00 23.63 ? 137 THR A CA     1 
ATOM   3095 C C      . THR B 2 137 ? 48.315 47.436  37.765 1.00 26.50 ? 137 THR A C      1 
ATOM   3096 O O      . THR B 2 137 ? 47.811 48.488  38.176 1.00 26.41 ? 137 THR A O      1 
ATOM   3097 C CB     . THR B 2 137 ? 47.391 45.591  39.164 1.00 22.59 ? 137 THR A CB     1 
ATOM   3098 O OG1    . THR B 2 137 ? 48.653 45.072  39.595 1.00 22.90 ? 137 THR A OG1    1 
ATOM   3099 C CG2    . THR B 2 137 ? 46.356 44.454  39.197 1.00 20.82 ? 137 THR A CG2    1 
ATOM   3100 H H      . THR B 2 137 ? 49.107 45.036  36.929 1.00 20.00 ? 137 THR A H      1 
ATOM   3101 H HG1    . THR B 2 137 ? 48.517 44.736  40.499 1.00 20.00 ? 137 THR A HG1    1 
ATOM   3102 N N      . GLN B 2 138 ? 49.553 47.350  37.305 1.00 29.12 ? 138 GLN A N      1 
ATOM   3103 C CA     . GLN B 2 138 ? 50.447 48.486  37.241 1.00 31.99 ? 138 GLN A CA     1 
ATOM   3104 C C      . GLN B 2 138 ? 50.706 48.894  35.807 1.00 26.58 ? 138 GLN A C      1 
ATOM   3105 O O      . GLN B 2 138 ? 51.143 48.079  34.993 1.00 26.89 ? 138 GLN A O      1 
ATOM   3106 C CB     . GLN B 2 138 ? 51.769 48.123  37.867 1.00 42.29 ? 138 GLN A CB     1 
ATOM   3107 C CG     . GLN B 2 138 ? 51.820 48.402  39.326 1.00 52.57 ? 138 GLN A CG     1 
ATOM   3108 C CD     . GLN B 2 138 ? 52.977 49.308  39.660 1.00 57.40 ? 138 GLN A CD     1 
ATOM   3109 O OE1    . GLN B 2 138 ? 52.785 50.490  39.984 1.00 59.49 ? 138 GLN A OE1    1 
ATOM   3110 N NE2    . GLN B 2 138 ? 54.198 48.777  39.552 1.00 60.66 ? 138 GLN A NE2    1 
ATOM   3111 H H      . GLN B 2 138 ? 49.860 46.506  36.939 1.00 20.00 ? 138 GLN A H      1 
ATOM   3112 H HE21   . GLN B 2 138 ? 54.952 49.353  39.756 1.00 20.00 ? 138 GLN A HE21   1 
ATOM   3113 H HE22   . GLN B 2 138 ? 54.279 47.845  39.269 1.00 20.00 ? 138 GLN A HE22   1 
ATOM   3114 N N      . PRO B 2 139 ? 50.436 50.157  35.473 1.00 18.37 ? 139 PRO A N      1 
ATOM   3115 C CA     . PRO B 2 139 ? 50.680 50.591  34.107 1.00 15.62 ? 139 PRO A CA     1 
ATOM   3116 C C      . PRO B 2 139 ? 52.172 50.496  33.733 1.00 13.66 ? 139 PRO A C      1 
ATOM   3117 O O      . PRO B 2 139 ? 53.031 50.364  34.607 1.00 13.36 ? 139 PRO A O      1 
ATOM   3118 C CB     . PRO B 2 139 ? 50.160 52.031  34.124 1.00 15.43 ? 139 PRO A CB     1 
ATOM   3119 C CG     . PRO B 2 139 ? 50.348 52.445  35.485 1.00 15.11 ? 139 PRO A CG     1 
ATOM   3120 C CD     . PRO B 2 139 ? 49.836 51.249  36.235 1.00 15.31 ? 139 PRO A CD     1 
ATOM   3121 N N      . GLY B 2 140 ? 52.464 50.453  32.437 1.00 11.11 ? 140 GLY A N      1 
ATOM   3122 C CA     . GLY B 2 140 ? 53.847 50.406  31.999 1.00 10.40 ? 140 GLY A CA     1 
ATOM   3123 C C      . GLY B 2 140 ? 54.495 51.792  31.871 1.00 7.67  ? 140 GLY A C      1 
ATOM   3124 O O      . GLY B 2 140 ? 53.937 52.836  32.279 1.00 11.25 ? 140 GLY A O      1 
ATOM   3125 H H      . GLY B 2 140 ? 51.749 50.505  31.765 1.00 20.00 ? 140 GLY A H      1 
ATOM   3126 N N      . LYS B 2 141 ? 55.646 51.825  31.206 1.00 3.69  ? 141 LYS A N      1 
ATOM   3127 C CA     . LYS B 2 141 ? 56.387 53.060  31.027 1.00 2.00  ? 141 LYS A CA     1 
ATOM   3128 C C      . LYS B 2 141 ? 57.093 53.228  29.671 1.00 2.15  ? 141 LYS A C      1 
ATOM   3129 O O      . LYS B 2 141 ? 57.649 52.264  29.103 1.00 2.93  ? 141 LYS A O      1 
ATOM   3130 C CB     . LYS B 2 141 ? 57.383 53.168  32.154 1.00 2.00  ? 141 LYS A CB     1 
ATOM   3131 C CG     . LYS B 2 141 ? 58.340 52.010  32.311 1.00 2.01  ? 141 LYS A CG     1 
ATOM   3132 C CD     . LYS B 2 141 ? 59.001 52.186  33.648 1.00 2.00  ? 141 LYS A CD     1 
ATOM   3133 C CE     . LYS B 2 141 ? 60.355 51.549  33.738 1.00 2.01  ? 141 LYS A CE     1 
ATOM   3134 N NZ     . LYS B 2 141 ? 60.845 51.794  35.109 1.00 2.01  ? 141 LYS A NZ     1 
ATOM   3135 H H      . LYS B 2 141 ? 56.003 51.002  30.828 1.00 20.00 ? 141 LYS A H      1 
ATOM   3136 H HZ1    . LYS B 2 141 ? 60.094 51.615  35.797 1.00 20.00 ? 141 LYS A HZ1    1 
ATOM   3137 H HZ2    . LYS B 2 141 ? 61.662 51.178  35.307 1.00 20.00 ? 141 LYS A HZ2    1 
ATOM   3138 H HZ3    . LYS B 2 141 ? 61.156 52.790  35.186 1.00 20.00 ? 141 LYS A HZ3    1 
ATOM   3139 N N      . ASN B 2 142 ? 57.130 54.470  29.187 1.00 2.01  ? 142 ASN A N      1 
ATOM   3140 C CA     . ASN B 2 142 ? 57.772 54.767  27.920 1.00 2.01  ? 142 ASN A CA     1 
ATOM   3141 C C      . ASN B 2 142 ? 59.250 54.479  27.934 1.00 2.00  ? 142 ASN A C      1 
ATOM   3142 O O      . ASN B 2 142 ? 59.987 54.903  28.828 1.00 2.00  ? 142 ASN A O      1 
ATOM   3143 C CB     . ASN B 2 142 ? 57.594 56.221  27.519 1.00 2.01  ? 142 ASN A CB     1 
ATOM   3144 C CG     . ASN B 2 142 ? 56.155 56.635  27.421 1.00 2.00  ? 142 ASN A CG     1 
ATOM   3145 O OD1    . ASN B 2 142 ? 55.849 57.818  27.580 1.00 2.00  ? 142 ASN A OD1    1 
ATOM   3146 N ND2    . ASN B 2 142 ? 55.254 55.678  27.138 1.00 2.43  ? 142 ASN A ND2    1 
ATOM   3147 H H      . ASN B 2 142 ? 56.748 55.199  29.721 1.00 20.00 ? 142 ASN A H      1 
ATOM   3148 H HD21   . ASN B 2 142 ? 54.327 55.961  27.059 1.00 20.00 ? 142 ASN A HD21   1 
ATOM   3149 H HD22   . ASN B 2 142 ? 55.560 54.760  27.002 1.00 20.00 ? 142 ASN A HD22   1 
ATOM   3150 N N      . SER B 2 143 ? 59.681 53.754  26.916 1.00 2.00  ? 143 SER A N      1 
ATOM   3151 C CA     . SER B 2 143 ? 61.080 53.415  26.751 1.00 3.53  ? 143 SER A CA     1 
ATOM   3152 C C      . SER B 2 143 ? 61.772 54.744  26.451 1.00 2.01  ? 143 SER A C      1 
ATOM   3153 O O      . SER B 2 143 ? 61.151 55.614  25.854 1.00 2.01  ? 143 SER A O      1 
ATOM   3154 C CB     . SER B 2 143 ? 61.201 52.461  25.559 1.00 2.00  ? 143 SER A CB     1 
ATOM   3155 O OG     . SER B 2 143 ? 62.437 52.614  24.896 1.00 2.00  ? 143 SER A OG     1 
ATOM   3156 H H      . SER B 2 143 ? 59.037 53.427  26.256 1.00 20.00 ? 143 SER A H      1 
ATOM   3157 H HG     . SER B 2 143 ? 62.439 52.003  24.282 1.00 20.00 ? 143 SER A HG     1 
ATOM   3158 N N      . PRO B 2 144 ? 63.055 54.894  26.829 1.00 2.01  ? 144 PRO A N      1 
ATOM   3159 C CA     . PRO B 2 144 ? 63.787 56.141  26.577 1.00 2.01  ? 144 PRO A CA     1 
ATOM   3160 C C      . PRO B 2 144 ? 64.033 56.361  25.079 1.00 2.07  ? 144 PRO A C      1 
ATOM   3161 O O      . PRO B 2 144 ? 64.360 57.460  24.632 1.00 2.01  ? 144 PRO A O      1 
ATOM   3162 C CB     . PRO B 2 144 ? 65.103 55.896  27.309 1.00 2.01  ? 144 PRO A CB     1 
ATOM   3163 C CG     . PRO B 2 144 ? 65.306 54.457  27.102 1.00 2.01  ? 144 PRO A CG     1 
ATOM   3164 C CD     . PRO B 2 144 ? 63.963 53.872  27.371 1.00 2.00  ? 144 PRO A CD     1 
ATOM   3165 N N      . TYR B 2 145 ? 63.815 55.319  24.295 1.00 2.01  ? 145 TYR A N      1 
ATOM   3166 C CA     . TYR B 2 145 ? 64.027 55.372  22.866 1.00 2.01  ? 145 TYR A CA     1 
ATOM   3167 C C      . TYR B 2 145 ? 62.732 55.720  22.144 1.00 2.00  ? 145 TYR A C      1 
ATOM   3168 O O      . TYR B 2 145 ? 62.736 55.939  20.941 1.00 2.01  ? 145 TYR A O      1 
ATOM   3169 C CB     . TYR B 2 145 ? 64.517 53.993  22.395 1.00 2.00  ? 145 TYR A CB     1 
ATOM   3170 C CG     . TYR B 2 145 ? 65.730 53.516  23.135 1.00 2.01  ? 145 TYR A CG     1 
ATOM   3171 C CD1    . TYR B 2 145 ? 66.976 54.102  22.921 1.00 2.01  ? 145 TYR A CD1    1 
ATOM   3172 C CD2    . TYR B 2 145 ? 65.619 52.551  24.105 1.00 2.01  ? 145 TYR A CD2    1 
ATOM   3173 C CE1    . TYR B 2 145 ? 68.083 53.745  23.664 1.00 2.01  ? 145 TYR A CE1    1 
ATOM   3174 C CE2    . TYR B 2 145 ? 66.713 52.187  24.863 1.00 2.01  ? 145 TYR A CE2    1 
ATOM   3175 C CZ     . TYR B 2 145 ? 67.946 52.790  24.640 1.00 2.01  ? 145 TYR A CZ     1 
ATOM   3176 O OH     . TYR B 2 145 ? 69.013 52.459  25.429 1.00 2.02  ? 145 TYR A OH     1 
ATOM   3177 H H      . TYR B 2 145 ? 63.517 54.482  24.702 1.00 20.00 ? 145 TYR A H      1 
ATOM   3178 H HH     . TYR B 2 145 ? 68.738 51.812  26.078 1.00 20.00 ? 145 TYR A HH     1 
ATOM   3179 N N      . ARG B 2 146 ? 61.631 55.798  22.874 1.00 3.80  ? 146 ARG A N      1 
ATOM   3180 C CA     . ARG B 2 146 ? 60.338 56.041  22.263 1.00 2.00  ? 146 ARG A CA     1 
ATOM   3181 C C      . ARG B 2 146 ? 60.153 57.295  21.438 1.00 2.53  ? 146 ARG A C      1 
ATOM   3182 O O      . ARG B 2 146 ? 59.274 57.337  20.598 1.00 3.08  ? 146 ARG A O      1 
ATOM   3183 C CB     . ARG B 2 146 ? 59.258 55.988  23.317 1.00 2.01  ? 146 ARG A CB     1 
ATOM   3184 C CG     . ARG B 2 146 ? 57.877 55.917  22.793 1.00 2.02  ? 146 ARG A CG     1 
ATOM   3185 C CD     . ARG B 2 146 ? 56.923 55.921  23.969 1.00 2.01  ? 146 ARG A CD     1 
ATOM   3186 N NE     . ARG B 2 146 ? 55.726 55.193  23.649 1.00 2.01  ? 146 ARG A NE     1 
ATOM   3187 C CZ     . ARG B 2 146 ? 54.536 55.746  23.553 1.00 2.01  ? 146 ARG A CZ     1 
ATOM   3188 N NH1    . ARG B 2 146 ? 54.407 57.039  23.804 1.00 2.01  ? 146 ARG A NH1    1 
ATOM   3189 N NH2    . ARG B 2 146 ? 53.483 55.001  23.233 1.00 2.01  ? 146 ARG A NH2    1 
ATOM   3190 H H      . ARG B 2 146 ? 61.690 55.737  23.853 1.00 20.00 ? 146 ARG A H      1 
ATOM   3191 H HE     . ARG B 2 146 ? 55.802 54.235  23.528 1.00 20.00 ? 146 ARG A HE     1 
ATOM   3192 H HH11   . ARG B 2 146 ? 55.209 57.582  24.026 1.00 20.00 ? 146 ARG A HH11   1 
ATOM   3193 H HH12   . ARG B 2 146 ? 53.513 57.475  23.715 1.00 20.00 ? 146 ARG A HH12   1 
ATOM   3194 H HH21   . ARG B 2 146 ? 53.578 54.017  23.126 1.00 20.00 ? 146 ARG A HH21   1 
ATOM   3195 H HH22   . ARG B 2 146 ? 52.571 55.417  23.197 1.00 20.00 ? 146 ARG A HH22   1 
ATOM   3196 N N      . ASP B 2 147 ? 60.938 58.336  21.656 1.00 3.16  ? 147 ASP A N      1 
ATOM   3197 C CA     . ASP B 2 147 ? 60.715 59.534  20.853 1.00 4.33  ? 147 ASP A CA     1 
ATOM   3198 C C      . ASP B 2 147 ? 61.784 59.833  19.806 1.00 3.44  ? 147 ASP A C      1 
ATOM   3199 O O      . ASP B 2 147 ? 62.227 60.964  19.641 1.00 2.01  ? 147 ASP A O      1 
ATOM   3200 C CB     . ASP B 2 147 ? 60.475 60.749  21.760 1.00 6.98  ? 147 ASP A CB     1 
ATOM   3201 C CG     . ASP B 2 147 ? 59.192 60.633  22.563 1.00 13.07 ? 147 ASP A CG     1 
ATOM   3202 O OD1    . ASP B 2 147 ? 58.135 60.286  21.978 1.00 12.47 ? 147 ASP A OD1    1 
ATOM   3203 O OD2    . ASP B 2 147 ? 59.229 60.907  23.776 1.00 16.76 ? 147 ASP A OD2    1 
ATOM   3204 H H      . ASP B 2 147 ? 61.669 58.285  22.296 1.00 20.00 ? 147 ASP A H      1 
ATOM   3205 N N      . ARG B 2 148 ? 62.248 58.811  19.111 1.00 2.35  ? 148 ARG A N      1 
ATOM   3206 C CA     . ARG B 2 148 ? 63.246 59.052  18.084 1.00 3.08  ? 148 ARG A CA     1 
ATOM   3207 C C      . ARG B 2 148 ? 62.482 59.714  16.942 1.00 4.18  ? 148 ARG A C      1 
ATOM   3208 O O      . ARG B 2 148 ? 61.254 59.596  16.850 1.00 5.19  ? 148 ARG A O      1 
ATOM   3209 C CB     . ARG B 2 148 ? 63.854 57.742  17.615 1.00 2.01  ? 148 ARG A CB     1 
ATOM   3210 C CG     . ARG B 2 148 ? 64.625 56.980  18.646 1.00 2.01  ? 148 ARG A CG     1 
ATOM   3211 C CD     . ARG B 2 148 ? 65.486 56.037  17.909 1.00 2.01  ? 148 ARG A CD     1 
ATOM   3212 N NE     . ARG B 2 148 ? 65.707 54.756  18.564 1.00 2.00  ? 148 ARG A NE     1 
ATOM   3213 C CZ     . ARG B 2 148 ? 66.901 54.326  18.964 1.00 2.01  ? 148 ARG A CZ     1 
ATOM   3214 N NH1    . ARG B 2 148 ? 67.960 55.114  18.899 1.00 2.01  ? 148 ARG A NH1    1 
ATOM   3215 N NH2    . ARG B 2 148 ? 67.021 53.141  19.519 1.00 2.00  ? 148 ARG A NH2    1 
ATOM   3216 H H      . ARG B 2 148 ? 61.901 57.903  19.265 1.00 20.00 ? 148 ARG A H      1 
ATOM   3217 H HE     . ARG B 2 148 ? 64.911 54.193  18.733 1.00 20.00 ? 148 ARG A HE     1 
ATOM   3218 H HH11   . ARG B 2 148 ? 67.868 56.023  18.487 1.00 20.00 ? 148 ARG A HH11   1 
ATOM   3219 H HH12   . ARG B 2 148 ? 68.842 54.764  19.175 1.00 20.00 ? 148 ARG A HH12   1 
ATOM   3220 H HH21   . ARG B 2 148 ? 66.185 52.589  19.683 1.00 20.00 ? 148 ARG A HH21   1 
ATOM   3221 H HH22   . ARG B 2 148 ? 67.882 52.837  19.856 1.00 20.00 ? 148 ARG A HH22   1 
ATOM   3222 N N      . SER B 2 149 ? 63.194 60.397  16.062 1.00 4.33  ? 149 SER A N      1 
ATOM   3223 C CA     . SER B 2 149 ? 62.575 61.058  14.921 1.00 5.98  ? 149 SER A CA     1 
ATOM   3224 C C      . SER B 2 149 ? 62.192 60.075  13.819 1.00 6.25  ? 149 SER A C      1 
ATOM   3225 O O      . SER B 2 149 ? 62.826 59.034  13.660 1.00 7.01  ? 149 SER A O      1 
ATOM   3226 C CB     . SER B 2 149 ? 63.562 62.071  14.362 1.00 9.44  ? 149 SER A CB     1 
ATOM   3227 O OG     . SER B 2 149 ? 64.836 61.479  14.175 1.00 9.40  ? 149 SER A OG     1 
ATOM   3228 H H      . SER B 2 149 ? 64.168 60.432  16.161 1.00 20.00 ? 149 SER A H      1 
ATOM   3229 H HG     . SER B 2 149 ? 65.443 62.144  13.797 1.00 20.00 ? 149 SER A HG     1 
ATOM   3230 N N      . VAL B 2 150 ? 61.204 60.435  13.008 1.00 6.20  ? 150 VAL A N      1 
ATOM   3231 C CA     . VAL B 2 150 ? 60.776 59.589  11.908 1.00 8.31  ? 150 VAL A CA     1 
ATOM   3232 C C      . VAL B 2 150 ? 61.995 59.221  11.101 1.00 11.72 ? 150 VAL A C      1 
ATOM   3233 O O      . VAL B 2 150 ? 62.205 58.076  10.723 1.00 13.46 ? 150 VAL A O      1 
ATOM   3234 C CB     . VAL B 2 150 ? 59.831 60.337  10.997 1.00 6.31  ? 150 VAL A CB     1 
ATOM   3235 C CG1    . VAL B 2 150 ? 59.711 59.630  9.670  1.00 5.06  ? 150 VAL A CG1    1 
ATOM   3236 C CG2    . VAL B 2 150 ? 58.483 60.470  11.649 1.00 6.93  ? 150 VAL A CG2    1 
ATOM   3237 H H      . VAL B 2 150 ? 60.675 61.211  13.222 1.00 20.00 ? 150 VAL A H      1 
ATOM   3238 N N      . GLU B 2 151 ? 62.838 60.207  10.889 1.00 17.62 ? 151 GLU A N      1 
ATOM   3239 C CA     . GLU B 2 151 ? 64.059 60.016  10.138 1.00 22.95 ? 151 GLU A CA     1 
ATOM   3240 C C      . GLU B 2 151 ? 64.951 58.994  10.818 1.00 18.28 ? 151 GLU A C      1 
ATOM   3241 O O      . GLU B 2 151 ? 65.484 58.110  10.179 1.00 16.96 ? 151 GLU A O      1 
ATOM   3242 C CB     . GLU B 2 151 ? 64.807 61.341  9.982  1.00 32.14 ? 151 GLU A CB     1 
ATOM   3243 C CG     . GLU B 2 151 ? 64.080 62.404  9.123  1.00 41.30 ? 151 GLU A CG     1 
ATOM   3244 C CD     . GLU B 2 151 ? 62.928 63.130  9.844  1.00 49.30 ? 151 GLU A CD     1 
ATOM   3245 O OE1    . GLU B 2 151 ? 63.071 63.482  11.041 1.00 50.31 ? 151 GLU A OE1    1 
ATOM   3246 O OE2    . GLU B 2 151 ? 61.883 63.376  9.192  1.00 51.56 ? 151 GLU A OE2    1 
ATOM   3247 H H      . GLU B 2 151 ? 62.608 61.069  11.233 1.00 20.00 ? 151 GLU A H      1 
ATOM   3248 N N      . GLU B 2 152 ? 65.076 59.082  12.124 1.00 13.62 ? 152 GLU A N      1 
ATOM   3249 C CA     . GLU B 2 152 ? 65.920 58.164  12.862 1.00 12.93 ? 152 GLU A CA     1 
ATOM   3250 C C      . GLU B 2 152 ? 65.387 56.740  12.804 1.00 9.35  ? 152 GLU A C      1 
ATOM   3251 O O      . GLU B 2 152 ? 66.132 55.753  12.714 1.00 9.27  ? 152 GLU A O      1 
ATOM   3252 C CB     . GLU B 2 152 ? 65.974 58.625  14.302 1.00 18.34 ? 152 GLU A CB     1 
ATOM   3253 C CG     . GLU B 2 152 ? 67.345 58.573  14.903 1.00 26.93 ? 152 GLU A CG     1 
ATOM   3254 C CD     . GLU B 2 152 ? 67.334 59.064  16.328 1.00 34.11 ? 152 GLU A CD     1 
ATOM   3255 O OE1    . GLU B 2 152 ? 66.897 60.227  16.547 1.00 35.32 ? 152 GLU A OE1    1 
ATOM   3256 O OE2    . GLU B 2 152 ? 67.741 58.271  17.220 1.00 36.12 ? 152 GLU A OE2    1 
ATOM   3257 H H      . GLU B 2 152 ? 64.548 59.727  12.613 1.00 20.00 ? 152 GLU A H      1 
ATOM   3258 N N      . ASN B 2 153 ? 64.077 56.634  12.874 1.00 5.41  ? 153 ASN A N      1 
ATOM   3259 C CA     . ASN B 2 153 ? 63.424 55.352  12.847 1.00 2.33  ? 153 ASN A CA     1 
ATOM   3260 C C      . ASN B 2 153 ? 63.550 54.693  11.506 1.00 2.84  ? 153 ASN A C      1 
ATOM   3261 O O      . ASN B 2 153 ? 63.763 53.473  11.439 1.00 2.00  ? 153 ASN A O      1 
ATOM   3262 C CB     . ASN B 2 153 ? 61.983 55.507  13.240 1.00 2.01  ? 153 ASN A CB     1 
ATOM   3263 C CG     . ASN B 2 153 ? 61.817 55.706  14.718 1.00 4.87  ? 153 ASN A CG     1 
ATOM   3264 O OD1    . ASN B 2 153 ? 60.823 56.261  15.163 1.00 6.50  ? 153 ASN A OD1    1 
ATOM   3265 N ND2    . ASN B 2 153 ? 62.778 55.208  15.500 1.00 4.18  ? 153 ASN A ND2    1 
ATOM   3266 H H      . ASN B 2 153 ? 63.547 57.438  12.959 1.00 20.00 ? 153 ASN A H      1 
ATOM   3267 H HD21   . ASN B 2 153 ? 62.688 55.321  16.469 1.00 20.00 ? 153 ASN A HD21   1 
ATOM   3268 H HD22   . ASN B 2 153 ? 63.545 54.729  15.107 1.00 20.00 ? 153 ASN A HD22   1 
ATOM   3269 N N      . LEU B 2 154 ? 63.486 55.492  10.442 1.00 2.00  ? 154 LEU A N      1 
ATOM   3270 C CA     . LEU B 2 154 ? 63.651 54.948  9.096  1.00 2.00  ? 154 LEU A CA     1 
ATOM   3271 C C      . LEU B 2 154 ? 65.062 54.341  8.979  1.00 2.01  ? 154 LEU A C      1 
ATOM   3272 O O      . LEU B 2 154 ? 65.250 53.192  8.544  1.00 2.01  ? 154 LEU A O      1 
ATOM   3273 C CB     . LEU B 2 154 ? 63.442 56.037  8.054  1.00 2.01  ? 154 LEU A CB     1 
ATOM   3274 C CG     . LEU B 2 154 ? 62.082 56.147  7.360  1.00 2.01  ? 154 LEU A CG     1 
ATOM   3275 C CD1    . LEU B 2 154 ? 61.040 55.224  7.958  1.00 2.00  ? 154 LEU A CD1    1 
ATOM   3276 C CD2    . LEU B 2 154 ? 61.604 57.565  7.410  1.00 2.01  ? 154 LEU A CD2    1 
ATOM   3277 H H      . LEU B 2 154 ? 63.268 56.428  10.555 1.00 20.00 ? 154 LEU A H      1 
ATOM   3278 N N      . ALA B 2 155 ? 66.042 55.081  9.480  1.00 2.01  ? 155 ALA A N      1 
ATOM   3279 C CA     . ALA B 2 155 ? 67.418 54.627  9.431  1.00 2.00  ? 155 ALA A CA     1 
ATOM   3280 C C      . ALA B 2 155 ? 67.610 53.360  10.226 1.00 2.00  ? 155 ALA A C      1 
ATOM   3281 O O      . ALA B 2 155 ? 68.160 52.376  9.712  1.00 2.01  ? 155 ALA A O      1 
ATOM   3282 C CB     . ALA B 2 155 ? 68.341 55.671  9.937  1.00 2.01  ? 155 ALA A CB     1 
ATOM   3283 H H      . ALA B 2 155 ? 65.833 55.948  9.894  1.00 20.00 ? 155 ALA A H      1 
ATOM   3284 N N      . LEU B 2 156 ? 67.151 53.355  11.474 1.00 2.01  ? 156 LEU A N      1 
ATOM   3285 C CA     . LEU B 2 156 ? 67.306 52.171  12.297 1.00 2.26  ? 156 LEU A CA     1 
ATOM   3286 C C      . LEU B 2 156 ? 66.546 50.960  11.764 1.00 3.71  ? 156 LEU A C      1 
ATOM   3287 O O      . LEU B 2 156 ? 67.047 49.824  11.835 1.00 2.00  ? 156 LEU A O      1 
ATOM   3288 C CB     . LEU B 2 156 ? 66.902 52.453  13.735 1.00 5.36  ? 156 LEU A CB     1 
ATOM   3289 C CG     . LEU B 2 156 ? 67.948 53.026  14.710 1.00 4.19  ? 156 LEU A CG     1 
ATOM   3290 C CD1    . LEU B 2 156 ? 69.323 53.076  14.084 1.00 2.82  ? 156 LEU A CD1    1 
ATOM   3291 C CD2    . LEU B 2 156 ? 67.536 54.403  15.192 1.00 5.97  ? 156 LEU A CD2    1 
ATOM   3292 H H      . LEU B 2 156 ? 66.728 54.153  11.837 1.00 20.00 ? 156 LEU A H      1 
ATOM   3293 N N      . PHE B 2 157 ? 65.359 51.185  11.194 1.00 3.57  ? 157 PHE A N      1 
ATOM   3294 C CA     . PHE B 2 157 ? 64.582 50.064  10.670 1.00 3.57  ? 157 PHE A CA     1 
ATOM   3295 C C      . PHE B 2 157 ? 65.344 49.375  9.503  1.00 4.71  ? 157 PHE A C      1 
ATOM   3296 O O      . PHE B 2 157 ? 65.524 48.149  9.486  1.00 2.01  ? 157 PHE A O      1 
ATOM   3297 C CB     . PHE B 2 157 ? 63.176 50.514  10.261 1.00 2.01  ? 157 PHE A CB     1 
ATOM   3298 C CG     . PHE B 2 157 ? 62.226 49.377  9.995  1.00 2.01  ? 157 PHE A CG     1 
ATOM   3299 C CD1    . PHE B 2 157 ? 62.232 48.233  10.780 1.00 2.00  ? 157 PHE A CD1    1 
ATOM   3300 C CD2    . PHE B 2 157 ? 61.310 49.456  8.964  1.00 2.00  ? 157 PHE A CD2    1 
ATOM   3301 C CE1    . PHE B 2 157 ? 61.347 47.184  10.548 1.00 2.00  ? 157 PHE A CE1    1 
ATOM   3302 C CE2    . PHE B 2 157 ? 60.409 48.398  8.716  1.00 2.01  ? 157 PHE A CE2    1 
ATOM   3303 C CZ     . PHE B 2 157 ? 60.430 47.269  9.514  1.00 2.01  ? 157 PHE A CZ     1 
ATOM   3304 H H      . PHE B 2 157 ? 65.014 52.089  11.129 1.00 20.00 ? 157 PHE A H      1 
ATOM   3305 N N      . GLU B 2 158 ? 65.851 50.168  8.564  1.00 8.69  ? 158 GLU A N      1 
ATOM   3306 C CA     . GLU B 2 158 ? 66.593 49.593  7.442  1.00 12.18 ? 158 GLU A CA     1 
ATOM   3307 C C      . GLU B 2 158 ? 67.857 48.884  7.925  1.00 10.82 ? 158 GLU A C      1 
ATOM   3308 O O      . GLU B 2 158 ? 68.290 47.905  7.321  1.00 11.08 ? 158 GLU A O      1 
ATOM   3309 C CB     . GLU B 2 158 ? 66.930 50.657  6.404  1.00 16.97 ? 158 GLU A CB     1 
ATOM   3310 C CG     . GLU B 2 158 ? 67.922 50.210  5.333  1.00 24.76 ? 158 GLU A CG     1 
ATOM   3311 C CD     . GLU B 2 158 ? 67.448 49.049  4.450  1.00 25.49 ? 158 GLU A CD     1 
ATOM   3312 O OE1    . GLU B 2 158 ? 66.217 48.802  4.336  1.00 26.92 ? 158 GLU A OE1    1 
ATOM   3313 O OE2    . GLU B 2 158 ? 68.338 48.400  3.851  1.00 26.53 ? 158 GLU A OE2    1 
ATOM   3314 H H      . GLU B 2 158 ? 65.772 51.145  8.655  1.00 20.00 ? 158 GLU A H      1 
ATOM   3315 N N      . LYS B 2 159 ? 68.432 49.365  9.026  1.00 10.00 ? 159 LYS A N      1 
ATOM   3316 C CA     . LYS B 2 159 ? 69.619 48.742  9.607  1.00 4.69  ? 159 LYS A CA     1 
ATOM   3317 C C      . LYS B 2 159 ? 69.165 47.379  10.103 1.00 2.00  ? 159 LYS A C      1 
ATOM   3318 O O      . LYS B 2 159 ? 69.840 46.376  9.902  1.00 2.83  ? 159 LYS A O      1 
ATOM   3319 C CB     . LYS B 2 159 ? 70.128 49.576  10.766 1.00 4.23  ? 159 LYS A CB     1 
ATOM   3320 C CG     . LYS B 2 159 ? 71.453 49.151  11.285 1.00 3.87  ? 159 LYS A CG     1 
ATOM   3321 C CD     . LYS B 2 159 ? 71.907 50.069  12.396 1.00 3.86  ? 159 LYS A CD     1 
ATOM   3322 C CE     . LYS B 2 159 ? 73.166 49.500  13.067 1.00 6.35  ? 159 LYS A CE     1 
ATOM   3323 N NZ     . LYS B 2 159 ? 73.378 50.069  14.430 1.00 5.59  ? 159 LYS A NZ     1 
ATOM   3324 H H      . LYS B 2 159 ? 68.034 50.137  9.464  1.00 20.00 ? 159 LYS A H      1 
ATOM   3325 H HZ1    . LYS B 2 159 ? 72.462 49.968  14.937 1.00 20.00 ? 159 LYS A HZ1    1 
ATOM   3326 H HZ2    . LYS B 2 159 ? 74.080 49.467  14.918 1.00 20.00 ? 159 LYS A HZ2    1 
ATOM   3327 H HZ3    . LYS B 2 159 ? 73.670 51.033  14.387 1.00 20.00 ? 159 LYS A HZ3    1 
ATOM   3328 N N      . MET B 2 160 ? 67.999 47.339  10.728 1.00 2.00  ? 160 MET A N      1 
ATOM   3329 C CA     . MET B 2 160 ? 67.459 46.070  11.174 1.00 2.51  ? 160 MET A CA     1 
ATOM   3330 C C      . MET B 2 160 ? 67.298 45.173  9.945  1.00 2.04  ? 160 MET A C      1 
ATOM   3331 O O      . MET B 2 160 ? 67.944 44.130  9.849  1.00 2.01  ? 160 MET A O      1 
ATOM   3332 C CB     . MET B 2 160 ? 66.083 46.243  11.835 1.00 2.58  ? 160 MET A CB     1 
ATOM   3333 C CG     . MET B 2 160 ? 66.120 46.689  13.274 1.00 2.00  ? 160 MET A CG     1 
ATOM   3334 S SD     . MET B 2 160 ? 64.488 46.889  13.870 1.00 2.02  ? 160 MET A SD     1 
ATOM   3335 C CE     . MET B 2 160 ? 63.990 45.172  13.779 1.00 2.01  ? 160 MET A CE     1 
ATOM   3336 H H      . MET B 2 160 ? 67.491 48.159  10.857 1.00 20.00 ? 160 MET A H      1 
ATOM   3337 N N      . ARG B 2 161 ? 66.509 45.642  8.978  1.00 2.33  ? 161 ARG A N      1 
ATOM   3338 C CA     . ARG B 2 161 ? 66.216 44.896  7.780  1.00 4.24  ? 161 ARG A CA     1 
ATOM   3339 C C      . ARG B 2 161 ? 67.468 44.405  7.144  1.00 4.88  ? 161 ARG A C      1 
ATOM   3340 O O      . ARG B 2 161 ? 67.541 43.247  6.751  1.00 7.45  ? 161 ARG A O      1 
ATOM   3341 C CB     . ARG B 2 161 ? 65.458 45.735  6.779  1.00 8.98  ? 161 ARG A CB     1 
ATOM   3342 C CG     . ARG B 2 161 ? 64.726 44.920  5.734  1.00 14.40 ? 161 ARG A CG     1 
ATOM   3343 C CD     . ARG B 2 161 ? 65.039 45.455  4.347  1.00 19.53 ? 161 ARG A CD     1 
ATOM   3344 N NE     . ARG B 2 161 ? 66.433 45.185  3.990  1.00 21.65 ? 161 ARG A NE     1 
ATOM   3345 C CZ     . ARG B 2 161 ? 67.135 45.865  3.086  1.00 24.05 ? 161 ARG A CZ     1 
ATOM   3346 N NH1    . ARG B 2 161 ? 66.584 46.894  2.444  1.00 24.69 ? 161 ARG A NH1    1 
ATOM   3347 N NH2    . ARG B 2 161 ? 68.397 45.519  2.822  1.00 24.21 ? 161 ARG A NH2    1 
ATOM   3348 H H      . ARG B 2 161 ? 66.095 46.488  9.091  1.00 20.00 ? 161 ARG A H      1 
ATOM   3349 H HE     . ARG B 2 161 ? 66.835 44.381  4.389  1.00 20.00 ? 161 ARG A HE     1 
ATOM   3350 H HH11   . ARG B 2 161 ? 65.642 47.146  2.628  1.00 20.00 ? 161 ARG A HH11   1 
ATOM   3351 H HH12   . ARG B 2 161 ? 67.133 47.397  1.781  1.00 20.00 ? 161 ARG A HH12   1 
ATOM   3352 H HH21   . ARG B 2 161 ? 68.779 44.687  3.263  1.00 20.00 ? 161 ARG A HH21   1 
ATOM   3353 H HH22   . ARG B 2 161 ? 68.922 45.999  2.139  1.00 20.00 ? 161 ARG A HH22   1 
ATOM   3354 N N      . ALA B 2 162 ? 68.471 45.277  7.066  1.00 6.05  ? 162 ALA A N      1 
ATOM   3355 C CA     . ALA B 2 162 ? 69.765 44.951  6.468  1.00 8.21  ? 162 ALA A CA     1 
ATOM   3356 C C      . ALA B 2 162 ? 70.716 44.163  7.383  1.00 9.65  ? 162 ALA A C      1 
ATOM   3357 O O      . ALA B 2 162 ? 71.929 44.202  7.231  1.00 8.70  ? 162 ALA A O      1 
ATOM   3358 C CB     . ALA B 2 162 ? 70.424 46.203  5.964  1.00 10.73 ? 162 ALA A CB     1 
ATOM   3359 H H      . ALA B 2 162 ? 68.335 46.151  7.413  1.00 20.00 ? 162 ALA A H      1 
ATOM   3360 N N      . GLY B 2 163 ? 70.155 43.487  8.375  1.00 12.45 ? 163 GLY A N      1 
ATOM   3361 C CA     . GLY B 2 163 ? 70.938 42.669  9.288  1.00 15.46 ? 163 GLY A CA     1 
ATOM   3362 C C      . GLY B 2 163 ? 72.078 43.306  10.057 1.00 15.93 ? 163 GLY A C      1 
ATOM   3363 O O      . GLY B 2 163 ? 73.035 42.613  10.407 1.00 17.56 ? 163 GLY A O      1 
ATOM   3364 H H      . GLY B 2 163 ? 69.187 43.551  8.507  1.00 20.00 ? 163 GLY A H      1 
ATOM   3365 N N      . GLY B 2 164 ? 71.955 44.595  10.364 1.00 13.40 ? 164 GLY A N      1 
ATOM   3366 C CA     . GLY B 2 164 ? 72.994 45.285  11.093 1.00 11.46 ? 164 GLY A CA     1 
ATOM   3367 C C      . GLY B 2 164 ? 72.900 45.158  12.597 1.00 10.29 ? 164 GLY A C      1 
ATOM   3368 O O      . GLY B 2 164 ? 73.826 45.549  13.300 1.00 11.83 ? 164 GLY A O      1 
ATOM   3369 H H      . GLY B 2 164 ? 71.173 45.090  10.074 1.00 20.00 ? 164 GLY A H      1 
ATOM   3370 N N      . PHE B 2 165 ? 71.772 44.660  13.098 1.00 8.05  ? 165 PHE A N      1 
ATOM   3371 C CA     . PHE B 2 165 ? 71.541 44.481  14.540 1.00 6.23  ? 165 PHE A CA     1 
ATOM   3372 C C      . PHE B 2 165 ? 71.484 43.004  14.898 1.00 8.70  ? 165 PHE A C      1 
ATOM   3373 O O      . PHE B 2 165 ? 70.914 42.199  14.156 1.00 9.08  ? 165 PHE A O      1 
ATOM   3374 C CB     . PHE B 2 165 ? 70.197 45.049  14.942 1.00 2.01  ? 165 PHE A CB     1 
ATOM   3375 C CG     . PHE B 2 165 ? 70.207 46.507  15.215 1.00 2.01  ? 165 PHE A CG     1 
ATOM   3376 C CD1    . PHE B 2 165 ? 70.764 47.002  16.366 1.00 2.00  ? 165 PHE A CD1    1 
ATOM   3377 C CD2    . PHE B 2 165 ? 69.620 47.382  14.340 1.00 2.01  ? 165 PHE A CD2    1 
ATOM   3378 C CE1    . PHE B 2 165 ? 70.732 48.356  16.638 1.00 2.00  ? 165 PHE A CE1    1 
ATOM   3379 C CE2    . PHE B 2 165 ? 69.587 48.728  14.606 1.00 2.01  ? 165 PHE A CE2    1 
ATOM   3380 C CZ     . PHE B 2 165 ? 70.140 49.218  15.754 1.00 2.01  ? 165 PHE A CZ     1 
ATOM   3381 H H      . PHE B 2 165 ? 71.068 44.395  12.469 1.00 20.00 ? 165 PHE A H      1 
ATOM   3382 N N      . GLU B 2 166 ? 71.996 42.653  16.069 1.00 12.61 ? 166 GLU A N      1 
ATOM   3383 C CA     . GLU B 2 166 ? 71.977 41.269  16.516 1.00 18.43 ? 166 GLU A CA     1 
ATOM   3384 C C      . GLU B 2 166 ? 70.574 40.910  16.952 1.00 13.39 ? 166 GLU A C      1 
ATOM   3385 O O      . GLU B 2 166 ? 69.746 41.781  17.162 1.00 8.47  ? 166 GLU A O      1 
ATOM   3386 C CB     . GLU B 2 166 ? 72.915 41.072  17.697 1.00 29.40 ? 166 GLU A CB     1 
ATOM   3387 C CG     . GLU B 2 166 ? 74.374 41.045  17.334 1.00 36.13 ? 166 GLU A CG     1 
ATOM   3388 C CD     . GLU B 2 166 ? 75.248 41.061  18.559 1.00 43.03 ? 166 GLU A CD     1 
ATOM   3389 O OE1    . GLU B 2 166 ? 75.106 40.153  19.414 1.00 43.73 ? 166 GLU A OE1    1 
ATOM   3390 O OE2    . GLU B 2 166 ? 76.075 41.992  18.680 1.00 43.12 ? 166 GLU A OE2    1 
ATOM   3391 H H      . GLU B 2 166 ? 72.437 43.327  16.604 1.00 20.00 ? 166 GLU A H      1 
ATOM   3392 N N      . GLU B 2 167 ? 70.305 39.628  17.118 1.00 11.40 ? 167 GLU A N      1 
ATOM   3393 C CA     . GLU B 2 167 ? 68.985 39.247  17.539 1.00 11.01 ? 167 GLU A CA     1 
ATOM   3394 C C      . GLU B 2 167 ? 68.721 39.854  18.897 1.00 7.45  ? 167 GLU A C      1 
ATOM   3395 O O      . GLU B 2 167 ? 69.609 39.926  19.726 1.00 6.37  ? 167 GLU A O      1 
ATOM   3396 C CB     . GLU B 2 167 ? 68.866 37.742  17.639 1.00 17.09 ? 167 GLU A CB     1 
ATOM   3397 C CG     . GLU B 2 167 ? 69.043 37.007  16.326 1.00 21.75 ? 167 GLU A CG     1 
ATOM   3398 C CD     . GLU B 2 167 ? 68.734 35.520  16.450 1.00 21.55 ? 167 GLU A CD     1 
ATOM   3399 O OE1    . GLU B 2 167 ? 68.208 35.098  17.518 1.00 22.04 ? 167 GLU A OE1    1 
ATOM   3400 O OE2    . GLU B 2 167 ? 69.012 34.774  15.480 1.00 24.04 ? 167 GLU A OE2    1 
ATOM   3401 H H      . GLU B 2 167 ? 71.003 38.964  17.013 1.00 20.00 ? 167 GLU A H      1 
ATOM   3402 N N      . GLY B 2 168 ? 67.510 40.359  19.091 1.00 5.62  ? 168 GLY A N      1 
ATOM   3403 C CA     . GLY B 2 168 ? 67.130 40.934  20.371 1.00 2.03  ? 168 GLY A CA     1 
ATOM   3404 C C      . GLY B 2 168 ? 67.706 42.291  20.675 1.00 2.00  ? 168 GLY A C      1 
ATOM   3405 O O      . GLY B 2 168 ? 67.270 42.968  21.588 1.00 2.01  ? 168 GLY A O      1 
ATOM   3406 H H      . GLY B 2 168 ? 66.858 40.321  18.374 1.00 20.00 ? 168 GLY A H      1 
ATOM   3407 N N      . LYS B 2 169 ? 68.640 42.730  19.861 1.00 2.00  ? 169 LYS A N      1 
ATOM   3408 C CA     . LYS B 2 169 ? 69.265 43.998  20.097 1.00 2.00  ? 169 LYS A CA     1 
ATOM   3409 C C      . LYS B 2 169 ? 68.459 45.212  19.681 1.00 2.01  ? 169 LYS A C      1 
ATOM   3410 O O      . LYS B 2 169 ? 68.875 46.355  19.954 1.00 2.00  ? 169 LYS A O      1 
ATOM   3411 C CB     . LYS B 2 169 ? 70.619 44.024  19.425 1.00 9.94  ? 169 LYS A CB     1 
ATOM   3412 C CG     . LYS B 2 169 ? 71.790 44.028  20.380 1.00 12.82 ? 169 LYS A CG     1 
ATOM   3413 C CD     . LYS B 2 169 ? 71.891 42.743  21.158 1.00 15.63 ? 169 LYS A CD     1 
ATOM   3414 C CE     . LYS B 2 169 ? 73.258 42.633  21.833 1.00 18.02 ? 169 LYS A CE     1 
ATOM   3415 N NZ     . LYS B 2 169 ? 73.590 43.871  22.573 1.00 21.11 ? 169 LYS A NZ     1 
ATOM   3416 H H      . LYS B 2 169 ? 68.896 42.207  19.080 1.00 20.00 ? 169 LYS A H      1 
ATOM   3417 H HZ1    . LYS B 2 169 ? 72.737 44.170  23.126 1.00 20.00 ? 169 LYS A HZ1    1 
ATOM   3418 H HZ2    . LYS B 2 169 ? 74.365 43.706  23.228 1.00 20.00 ? 169 LYS A HZ2    1 
ATOM   3419 H HZ3    . LYS B 2 169 ? 73.822 44.633  21.910 1.00 20.00 ? 169 LYS A HZ3    1 
ATOM   3420 N N      . ALA B 2 170 ? 67.345 44.997  18.994 1.00 2.01  ? 170 ALA A N      1 
ATOM   3421 C CA     . ALA B 2 170 ? 66.500 46.106  18.540 1.00 2.01  ? 170 ALA A CA     1 
ATOM   3422 C C      . ALA B 2 170 ? 65.266 45.557  17.907 1.00 2.01  ? 170 ALA A C      1 
ATOM   3423 O O      . ALA B 2 170 ? 65.312 44.498  17.324 1.00 2.00  ? 170 ALA A O      1 
ATOM   3424 C CB     . ALA B 2 170 ? 67.237 46.946  17.495 1.00 2.01  ? 170 ALA A CB     1 
ATOM   3425 H H      . ALA B 2 170 ? 67.076 44.073  18.766 1.00 20.00 ? 170 ALA A H      1 
ATOM   3426 N N      . CYS B 2 171 ? 64.152 46.242  18.036 1.00 2.01  ? 171 CYS A N      1 
ATOM   3427 C CA     . CYS B 2 171 ? 62.970 45.744  17.388 1.00 2.00  ? 171 CYS A CA     1 
ATOM   3428 C C      . CYS B 2 171 ? 62.065 46.917  17.078 1.00 2.00  ? 171 CYS A C      1 
ATOM   3429 O O      . CYS B 2 171 ? 62.325 48.011  17.555 1.00 2.00  ? 171 CYS A O      1 
ATOM   3430 C CB     . CYS B 2 171 ? 62.306 44.717  18.280 1.00 2.00  ? 171 CYS A CB     1 
ATOM   3431 S SG     . CYS B 2 171 ? 61.443 45.436  19.714 1.00 8.24  ? 171 CYS A SG     1 
ATOM   3432 H H      . CYS B 2 171 ? 64.125 47.084  18.533 1.00 20.00 ? 171 CYS A H      1 
ATOM   3433 N N      . LEU B 2 172 ? 61.044 46.724  16.247 1.00 2.01  ? 172 LEU A N      1 
ATOM   3434 C CA     . LEU B 2 172 ? 60.142 47.811  15.895 1.00 2.01  ? 172 LEU A CA     1 
ATOM   3435 C C      . LEU B 2 172 ? 58.925 47.675  16.753 1.00 2.01  ? 172 LEU A C      1 
ATOM   3436 O O      . LEU B 2 172 ? 58.478 46.566  16.941 1.00 2.01  ? 172 LEU A O      1 
ATOM   3437 C CB     . LEU B 2 172 ? 59.760 47.690  14.427 1.00 2.02  ? 172 LEU A CB     1 
ATOM   3438 C CG     . LEU B 2 172 ? 59.142 48.910  13.794 1.00 2.01  ? 172 LEU A CG     1 
ATOM   3439 C CD1    . LEU B 2 172 ? 60.065 50.078  13.886 1.00 2.01  ? 172 LEU A CD1    1 
ATOM   3440 C CD2    . LEU B 2 172 ? 58.855 48.609  12.356 1.00 2.01  ? 172 LEU A CD2    1 
ATOM   3441 H H      . LEU B 2 172 ? 60.862 45.820  15.906 1.00 20.00 ? 172 LEU A H      1 
ATOM   3442 N N      . ARG B 2 173 ? 58.378 48.787  17.253 1.00 2.01  ? 173 ARG A N      1 
ATOM   3443 C CA     . ARG B 2 173 ? 57.198 48.776  18.140 1.00 2.01  ? 173 ARG A CA     1 
ATOM   3444 C C      . ARG B 2 173 ? 56.123 49.784  17.783 1.00 2.01  ? 173 ARG A C      1 
ATOM   3445 O O      . ARG B 2 173 ? 56.422 50.868  17.308 1.00 2.00  ? 173 ARG A O      1 
ATOM   3446 C CB     . ARG B 2 173 ? 57.620 49.121  19.548 1.00 2.01  ? 173 ARG A CB     1 
ATOM   3447 C CG     . ARG B 2 173 ? 58.639 48.224  20.114 1.00 2.01  ? 173 ARG A CG     1 
ATOM   3448 C CD     . ARG B 2 173 ? 58.114 47.693  21.375 1.00 2.01  ? 173 ARG A CD     1 
ATOM   3449 N NE     . ARG B 2 173 ? 58.809 48.215  22.531 1.00 2.01  ? 173 ARG A NE     1 
ATOM   3450 C CZ     . ARG B 2 173 ? 58.311 48.154  23.754 1.00 2.01  ? 173 ARG A CZ     1 
ATOM   3451 N NH1    . ARG B 2 173 ? 57.081 47.686  23.963 1.00 2.01  ? 173 ARG A NH1    1 
ATOM   3452 N NH2    . ARG B 2 173 ? 59.031 48.617  24.757 1.00 2.01  ? 173 ARG A NH2    1 
ATOM   3453 H H      . ARG B 2 173 ? 58.773 49.654  17.021 1.00 20.00 ? 173 ARG A H      1 
ATOM   3454 H HE     . ARG B 2 173 ? 59.646 48.663  22.402 1.00 20.00 ? 173 ARG A HE     1 
ATOM   3455 H HH11   . ARG B 2 173 ? 56.513 47.344  23.211 1.00 20.00 ? 173 ARG A HH11   1 
ATOM   3456 H HH12   . ARG B 2 173 ? 56.716 47.605  24.907 1.00 20.00 ? 173 ARG A HH12   1 
ATOM   3457 H HH21   . ARG B 2 173 ? 59.906 49.030  24.578 1.00 20.00 ? 173 ARG A HH21   1 
ATOM   3458 H HH22   . ARG B 2 173 ? 58.659 48.572  25.690 1.00 20.00 ? 173 ARG A HH22   1 
ATOM   3459 N N      . ALA B 2 174 ? 54.871 49.448  18.028 1.00 2.01  ? 174 ALA A N      1 
ATOM   3460 C CA     . ALA B 2 174 ? 53.797 50.373  17.749 1.00 2.00  ? 174 ALA A CA     1 
ATOM   3461 C C      . ALA B 2 174 ? 53.808 51.430  18.865 1.00 2.01  ? 174 ALA A C      1 
ATOM   3462 O O      . ALA B 2 174 ? 54.116 51.144  20.017 1.00 2.01  ? 174 ALA A O      1 
ATOM   3463 C CB     . ALA B 2 174 ? 52.492 49.657  17.721 1.00 2.01  ? 174 ALA A CB     1 
ATOM   3464 H H      . ALA B 2 174 ? 54.667 48.558  18.383 1.00 20.00 ? 174 ALA A H      1 
ATOM   3465 N N      . LYS B 2 175 ? 53.498 52.665  18.526 1.00 2.00  ? 175 LYS A N      1 
ATOM   3466 C CA     . LYS B 2 175 ? 53.493 53.709  19.524 1.00 2.00  ? 175 LYS A CA     1 
ATOM   3467 C C      . LYS B 2 175 ? 52.042 53.920  19.951 1.00 2.00  ? 175 LYS A C      1 
ATOM   3468 O O      . LYS B 2 175 ? 51.337 54.749  19.385 1.00 2.01  ? 175 LYS A O      1 
ATOM   3469 C CB     . LYS B 2 175 ? 54.072 54.971  18.918 1.00 2.00  ? 175 LYS A CB     1 
ATOM   3470 C CG     . LYS B 2 175 ? 54.547 55.910  19.940 1.00 2.00  ? 175 LYS A CG     1 
ATOM   3471 C CD     . LYS B 2 175 ? 54.917 57.217  19.305 1.00 3.42  ? 175 LYS A CD     1 
ATOM   3472 C CE     . LYS B 2 175 ? 56.321 57.209  18.824 1.00 3.35  ? 175 LYS A CE     1 
ATOM   3473 N NZ     . LYS B 2 175 ? 56.760 58.593  18.585 1.00 3.08  ? 175 LYS A NZ     1 
ATOM   3474 H H      . LYS B 2 175 ? 53.292 52.874  17.592 1.00 20.00 ? 175 LYS A H      1 
ATOM   3475 H HZ1    . LYS B 2 175 ? 56.517 59.195  19.387 1.00 20.00 ? 175 LYS A HZ1    1 
ATOM   3476 H HZ2    . LYS B 2 175 ? 57.815 58.591  18.479 1.00 20.00 ? 175 LYS A HZ2    1 
ATOM   3477 H HZ3    . LYS B 2 175 ? 56.351 58.960  17.710 1.00 20.00 ? 175 LYS A HZ3    1 
ATOM   3478 N N      . ILE B 2 176 ? 51.587 53.141  20.924 1.00 2.01  ? 176 ILE A N      1 
ATOM   3479 C CA     . ILE B 2 176 ? 50.218 53.238  21.369 1.00 2.01  ? 176 ILE A CA     1 
ATOM   3480 C C      . ILE B 2 176 ? 50.100 53.855  22.727 1.00 2.00  ? 176 ILE A C      1 
ATOM   3481 O O      . ILE B 2 176 ? 50.376 55.019  22.861 1.00 4.56  ? 176 ILE A O      1 
ATOM   3482 C CB     . ILE B 2 176 ? 49.508 51.891  21.339 1.00 2.01  ? 176 ILE A CB     1 
ATOM   3483 C CG1    . ILE B 2 176 ? 49.674 51.251  19.963 1.00 2.00  ? 176 ILE A CG1    1 
ATOM   3484 C CG2    . ILE B 2 176 ? 48.064 52.076  21.627 1.00 2.01  ? 176 ILE A CG2    1 
ATOM   3485 C CD1    . ILE B 2 176 ? 48.889 49.966  19.743 1.00 2.00  ? 176 ILE A CD1    1 
ATOM   3486 H H      . ILE B 2 176 ? 52.201 52.530  21.361 1.00 20.00 ? 176 ILE A H      1 
ATOM   3487 N N      . ASP B 2 177 ? 49.782 53.075  23.748 1.00 3.01  ? 177 ASP A N      1 
ATOM   3488 C CA     . ASP B 2 177 ? 49.593 53.617  25.088 1.00 3.04  ? 177 ASP A CA     1 
ATOM   3489 C C      . ASP B 2 177 ? 50.133 52.701  26.196 1.00 2.03  ? 177 ASP A C      1 
ATOM   3490 O O      . ASP B 2 177 ? 49.463 51.768  26.604 1.00 2.00  ? 177 ASP A O      1 
ATOM   3491 C CB     . ASP B 2 177 ? 48.095 53.843  25.306 1.00 6.84  ? 177 ASP A CB     1 
ATOM   3492 C CG     . ASP B 2 177 ? 47.784 54.498  26.635 1.00 12.52 ? 177 ASP A CG     1 
ATOM   3493 O OD1    . ASP B 2 177 ? 48.732 54.861  27.377 1.00 9.60  ? 177 ASP A OD1    1 
ATOM   3494 O OD2    . ASP B 2 177 ? 46.576 54.663  26.931 1.00 17.07 ? 177 ASP A OD2    1 
ATOM   3495 H H      . ASP B 2 177 ? 49.673 52.107  23.629 1.00 20.00 ? 177 ASP A H      1 
ATOM   3496 N N      . MET B 2 178 ? 51.273 53.040  26.775 1.00 2.00  ? 178 MET A N      1 
ATOM   3497 C CA     . MET B 2 178 ? 51.867 52.206  27.819 1.00 2.00  ? 178 MET A CA     1 
ATOM   3498 C C      . MET B 2 178 ? 51.054 52.042  29.095 1.00 3.45  ? 178 MET A C      1 
ATOM   3499 O O      . MET B 2 178 ? 51.467 51.286  29.983 1.00 2.00  ? 178 MET A O      1 
ATOM   3500 C CB     . MET B 2 178 ? 53.243 52.727  28.202 1.00 2.00  ? 178 MET A CB     1 
ATOM   3501 C CG     . MET B 2 178 ? 54.230 52.638  27.090 1.00 2.01  ? 178 MET A CG     1 
ATOM   3502 S SD     . MET B 2 178 ? 54.374 50.910  26.591 1.00 5.00  ? 178 MET A SD     1 
ATOM   3503 C CE     . MET B 2 178 ? 55.727 50.401  27.670 1.00 2.00  ? 178 MET A CE     1 
ATOM   3504 H H      . MET B 2 178 ? 51.724 53.848  26.487 1.00 20.00 ? 178 MET A H      1 
ATOM   3505 N N      . ALA B 2 179 ? 49.954 52.797  29.222 1.00 3.72  ? 179 ALA A N      1 
ATOM   3506 C CA     . ALA B 2 179 ? 49.107 52.723  30.405 1.00 2.00  ? 179 ALA A CA     1 
ATOM   3507 C C      . ALA B 2 179 ? 47.754 52.115  30.102 1.00 2.00  ? 179 ALA A C      1 
ATOM   3508 O O      . ALA B 2 179 ? 46.883 52.044  30.958 1.00 2.31  ? 179 ALA A O      1 
ATOM   3509 C CB     . ALA B 2 179 ? 48.916 54.076  31.007 1.00 2.01  ? 179 ALA A CB     1 
ATOM   3510 H H      . ALA B 2 179 ? 49.700 53.394  28.491 1.00 20.00 ? 179 ALA A H      1 
ATOM   3511 N N      . SER B 2 180 ? 47.578 51.681  28.867 1.00 2.00  ? 180 SER A N      1 
ATOM   3512 C CA     . SER B 2 180 ? 46.324 51.081  28.466 1.00 2.00  ? 180 SER A CA     1 
ATOM   3513 C C      . SER B 2 180 ? 46.016 49.884  29.330 1.00 2.01  ? 180 SER A C      1 
ATOM   3514 O O      . SER B 2 180 ? 46.904 49.138  29.709 1.00 2.00  ? 180 SER A O      1 
ATOM   3515 C CB     . SER B 2 180 ? 46.365 50.623  27.001 1.00 2.77  ? 180 SER A CB     1 
ATOM   3516 O OG     . SER B 2 180 ? 45.170 49.930  26.658 1.00 4.34  ? 180 SER A OG     1 
ATOM   3517 H H      . SER B 2 180 ? 48.313 51.733  28.215 1.00 20.00 ? 180 SER A H      1 
ATOM   3518 H HG     . SER B 2 180 ? 45.240 49.667  25.732 1.00 20.00 ? 180 SER A HG     1 
ATOM   3519 N N      . PRO B 2 181 ? 44.752 49.706  29.667 1.00 2.01  ? 181 PRO A N      1 
ATOM   3520 C CA     . PRO B 2 181 ? 44.425 48.550  30.490 1.00 2.01  ? 181 PRO A CA     1 
ATOM   3521 C C      . PRO B 2 181 ? 44.660 47.259  29.692 1.00 2.01  ? 181 PRO A C      1 
ATOM   3522 O O      . PRO B 2 181 ? 44.844 46.199  30.279 1.00 2.00  ? 181 PRO A O      1 
ATOM   3523 C CB     . PRO B 2 181 ? 42.944 48.773  30.820 1.00 2.01  ? 181 PRO A CB     1 
ATOM   3524 C CG     . PRO B 2 181 ? 42.488 49.815  29.844 1.00 2.01  ? 181 PRO A CG     1 
ATOM   3525 C CD     . PRO B 2 181 ? 43.673 50.693  29.683 1.00 2.37  ? 181 PRO A CD     1 
ATOM   3526 N N      . PHE B 2 182 ? 44.607 47.341  28.361 1.00 2.01  ? 182 PHE A N      1 
ATOM   3527 C CA     . PHE B 2 182 ? 44.868 46.161  27.522 1.00 2.00  ? 182 PHE A CA     1 
ATOM   3528 C C      . PHE B 2 182 ? 46.391 46.001  27.469 1.00 3.08  ? 182 PHE A C      1 
ATOM   3529 O O      . PHE B 2 182 ? 47.082 46.911  26.977 1.00 2.00  ? 182 PHE A O      1 
ATOM   3530 C CB     . PHE B 2 182 ? 44.341 46.381  26.099 1.00 2.01  ? 182 PHE A CB     1 
ATOM   3531 C CG     . PHE B 2 182 ? 42.833 46.436  26.004 1.00 2.00  ? 182 PHE A CG     1 
ATOM   3532 C CD1    . PHE B 2 182 ? 42.094 45.264  25.889 1.00 2.01  ? 182 PHE A CD1    1 
ATOM   3533 C CD2    . PHE B 2 182 ? 42.159 47.648  26.073 1.00 2.01  ? 182 PHE A CD2    1 
ATOM   3534 C CE1    . PHE B 2 182 ? 40.734 45.312  25.854 1.00 2.00  ? 182 PHE A CE1    1 
ATOM   3535 C CE2    . PHE B 2 182 ? 40.805 47.697  26.039 1.00 2.01  ? 182 PHE A CE2    1 
ATOM   3536 C CZ     . PHE B 2 182 ? 40.088 46.537  25.934 1.00 2.00  ? 182 PHE A CZ     1 
ATOM   3537 H H      . PHE B 2 182 ? 44.474 48.207  27.940 1.00 20.00 ? 182 PHE A H      1 
ATOM   3538 N N      . ILE B 2 183 ? 46.929 44.871  27.957 1.00 2.00  ? 183 ILE A N      1 
ATOM   3539 C CA     . ILE B 2 183 ? 48.377 44.684  27.914 1.00 2.00  ? 183 ILE A CA     1 
ATOM   3540 C C      . ILE B 2 183 ? 48.820 44.638  26.470 1.00 2.00  ? 183 ILE A C      1 
ATOM   3541 O O      . ILE B 2 183 ? 49.922 45.054  26.128 1.00 2.21  ? 183 ILE A O      1 
ATOM   3542 C CB     . ILE B 2 183 ? 48.869 43.383  28.624 1.00 3.88  ? 183 ILE A CB     1 
ATOM   3543 C CG1    . ILE B 2 183 ? 48.814 43.529  30.140 1.00 4.09  ? 183 ILE A CG1    1 
ATOM   3544 C CG2    . ILE B 2 183 ? 50.295 43.049  28.214 1.00 5.44  ? 183 ILE A CG2    1 
ATOM   3545 C CD1    . ILE B 2 183 ? 47.454 43.320  30.673 1.00 7.68  ? 183 ILE A CD1    1 
ATOM   3546 H H      . ILE B 2 183 ? 46.351 44.192  28.358 1.00 20.00 ? 183 ILE A H      1 
ATOM   3547 N N      . VAL B 2 184 ? 47.931 44.190  25.595 1.00 2.00  ? 184 VAL A N      1 
ATOM   3548 C CA     . VAL B 2 184 ? 48.290 44.093  24.191 1.00 2.00  ? 184 VAL A CA     1 
ATOM   3549 C C      . VAL B 2 184 ? 48.528 45.409  23.489 1.00 2.00  ? 184 VAL A C      1 
ATOM   3550 O O      . VAL B 2 184 ? 49.168 45.404  22.460 1.00 2.00  ? 184 VAL A O      1 
ATOM   3551 C CB     . VAL B 2 184 ? 47.296 43.225  23.387 1.00 2.00  ? 184 VAL A CB     1 
ATOM   3552 C CG1    . VAL B 2 184 ? 46.007 43.986  23.080 1.00 2.01  ? 184 VAL A CG1    1 
ATOM   3553 C CG2    . VAL B 2 184 ? 47.949 42.736  22.134 1.00 2.01  ? 184 VAL A CG2    1 
ATOM   3554 H H      . VAL B 2 184 ? 47.044 43.927  25.900 1.00 20.00 ? 184 VAL A H      1 
ATOM   3555 N N      . MET B 2 185 ? 48.062 46.529  24.043 1.00 2.00  ? 185 MET A N      1 
ATOM   3556 C CA     . MET B 2 185 ? 48.262 47.835  23.406 1.00 2.01  ? 185 MET A CA     1 
ATOM   3557 C C      . MET B 2 185 ? 49.409 48.639  23.997 1.00 2.01  ? 185 MET A C      1 
ATOM   3558 O O      . MET B 2 185 ? 49.554 49.818  23.682 1.00 2.01  ? 185 MET A O      1 
ATOM   3559 C CB     . MET B 2 185 ? 47.012 48.695  23.497 1.00 2.01  ? 185 MET A CB     1 
ATOM   3560 C CG     . MET B 2 185 ? 45.783 48.033  22.993 1.00 2.01  ? 185 MET A CG     1 
ATOM   3561 S SD     . MET B 2 185 ? 45.797 48.012  21.265 1.00 7.56  ? 185 MET A SD     1 
ATOM   3562 C CE     . MET B 2 185 ? 44.994 49.577  20.892 1.00 4.12  ? 185 MET A CE     1 
ATOM   3563 H H      . MET B 2 185 ? 47.572 46.488  24.898 1.00 20.00 ? 185 MET A H      1 
ATOM   3564 N N      . ARG B 2 186 ? 50.201 48.033  24.878 1.00 2.01  ? 186 ARG A N      1 
ATOM   3565 C CA     . ARG B 2 186 ? 51.336 48.738  25.482 1.00 2.01  ? 186 ARG A CA     1 
ATOM   3566 C C      . ARG B 2 186 ? 52.555 48.629  24.559 1.00 2.01  ? 186 ARG A C      1 
ATOM   3567 O O      . ARG B 2 186 ? 53.503 47.897  24.842 1.00 2.00  ? 186 ARG A O      1 
ATOM   3568 C CB     . ARG B 2 186 ? 51.678 48.159  26.867 1.00 2.01  ? 186 ARG A CB     1 
ATOM   3569 C CG     . ARG B 2 186 ? 50.467 47.889  27.753 1.00 2.00  ? 186 ARG A CG     1 
ATOM   3570 C CD     . ARG B 2 186 ? 50.463 48.690  29.050 1.00 2.00  ? 186 ARG A CD     1 
ATOM   3571 N NE     . ARG B 2 186 ? 50.781 47.850  30.184 1.00 2.01  ? 186 ARG A NE     1 
ATOM   3572 C CZ     . ARG B 2 186 ? 49.948 47.592  31.179 1.00 2.00  ? 186 ARG A CZ     1 
ATOM   3573 N NH1    . ARG B 2 186 ? 48.751 48.158  31.225 1.00 2.00  ? 186 ARG A NH1    1 
ATOM   3574 N NH2    . ARG B 2 186 ? 50.334 46.797  32.162 1.00 2.01  ? 186 ARG A NH2    1 
ATOM   3575 H H      . ARG B 2 186 ? 50.009 47.102  25.145 1.00 20.00 ? 186 ARG A H      1 
ATOM   3576 H HE     . ARG B 2 186 ? 51.665 47.461  30.217 1.00 20.00 ? 186 ARG A HE     1 
ATOM   3577 H HH11   . ARG B 2 186 ? 48.477 48.809  30.522 1.00 20.00 ? 186 ARG A HH11   1 
ATOM   3578 H HH12   . ARG B 2 186 ? 48.137 47.979  31.997 1.00 20.00 ? 186 ARG A HH12   1 
ATOM   3579 H HH21   . ARG B 2 186 ? 51.247 46.395  32.156 1.00 20.00 ? 186 ARG A HH21   1 
ATOM   3580 H HH22   . ARG B 2 186 ? 49.713 46.611  32.925 1.00 20.00 ? 186 ARG A HH22   1 
ATOM   3581 N N      . ASP B 2 187 ? 52.496 49.352  23.442 1.00 2.01  ? 187 ASP A N      1 
ATOM   3582 C CA     . ASP B 2 187 ? 53.555 49.390  22.448 1.00 2.01  ? 187 ASP A CA     1 
ATOM   3583 C C      . ASP B 2 187 ? 53.952 48.026  21.893 1.00 2.01  ? 187 ASP A C      1 
ATOM   3584 O O      . ASP B 2 187 ? 55.137 47.713  21.792 1.00 2.01  ? 187 ASP A O      1 
ATOM   3585 C CB     . ASP B 2 187 ? 54.793 50.094  23.005 1.00 4.04  ? 187 ASP A CB     1 
ATOM   3586 C CG     . ASP B 2 187 ? 54.648 51.604  23.061 1.00 2.01  ? 187 ASP A CG     1 
ATOM   3587 O OD1    . ASP B 2 187 ? 53.504 52.096  23.055 1.00 2.01  ? 187 ASP A OD1    1 
ATOM   3588 O OD2    . ASP B 2 187 ? 55.688 52.291  23.116 1.00 2.01  ? 187 ASP A OD2    1 
ATOM   3589 H H      . ASP B 2 187 ? 51.674 49.855  23.274 1.00 20.00 ? 187 ASP A H      1 
ATOM   3590 N N      . PRO B 2 188 ? 52.970 47.216  21.466 1.00 2.01  ? 188 PRO A N      1 
ATOM   3591 C CA     . PRO B 2 188 ? 53.193 45.886  20.912 1.00 2.01  ? 188 PRO A CA     1 
ATOM   3592 C C      . PRO B 2 188 ? 54.269 45.864  19.855 1.00 2.01  ? 188 PRO A C      1 
ATOM   3593 O O      . PRO B 2 188 ? 54.250 46.704  18.962 1.00 2.01  ? 188 PRO A O      1 
ATOM   3594 C CB     . PRO B 2 188 ? 51.846 45.574  20.270 1.00 2.00  ? 188 PRO A CB     1 
ATOM   3595 C CG     . PRO B 2 188 ? 51.370 46.885  19.817 1.00 2.01  ? 188 PRO A CG     1 
ATOM   3596 C CD     . PRO B 2 188 ? 51.632 47.686  21.072 1.00 2.00  ? 188 PRO A CD     1 
ATOM   3597 N N      . VAL B 2 189 ? 55.203 44.916  19.979 1.00 2.01  ? 189 VAL A N      1 
ATOM   3598 C CA     . VAL B 2 189 ? 56.274 44.731  19.020 1.00 2.01  ? 189 VAL A CA     1 
ATOM   3599 C C      . VAL B 2 189 ? 55.594 44.373  17.704 1.00 2.00  ? 189 VAL A C      1 
ATOM   3600 O O      . VAL B 2 189 ? 54.526 43.727  17.685 1.00 2.01  ? 189 VAL A O      1 
ATOM   3601 C CB     . VAL B 2 189 ? 57.172 43.561  19.400 1.00 2.01  ? 189 VAL A CB     1 
ATOM   3602 C CG1    . VAL B 2 189 ? 58.322 43.427  18.428 1.00 2.01  ? 189 VAL A CG1    1 
ATOM   3603 C CG2    . VAL B 2 189 ? 57.674 43.750  20.786 1.00 2.00  ? 189 VAL A CG2    1 
ATOM   3604 H H      . VAL B 2 189 ? 55.121 44.286  20.729 1.00 20.00 ? 189 VAL A H      1 
ATOM   3605 N N      . LEU B 2 190 ? 56.185 44.874  16.625 1.00 2.00  ? 190 LEU A N      1 
ATOM   3606 C CA     . LEU B 2 190 ? 55.704 44.647  15.272 1.00 2.01  ? 190 LEU A CA     1 
ATOM   3607 C C      . LEU B 2 190 ? 56.699 43.824  14.458 1.00 2.01  ? 190 LEU A C      1 
ATOM   3608 O O      . LEU B 2 190 ? 56.298 43.090  13.568 1.00 2.01  ? 190 LEU A O      1 
ATOM   3609 C CB     . LEU B 2 190 ? 55.434 45.969  14.564 1.00 2.01  ? 190 LEU A CB     1 
ATOM   3610 C CG     . LEU B 2 190 ? 54.032 46.553  14.629 1.00 2.01  ? 190 LEU A CG     1 
ATOM   3611 C CD1    . LEU B 2 190 ? 53.367 46.330  15.967 1.00 2.01  ? 190 LEU A CD1    1 
ATOM   3612 C CD2    . LEU B 2 190 ? 54.126 48.020  14.310 1.00 2.01  ? 190 LEU A CD2    1 
ATOM   3613 H H      . LEU B 2 190 ? 56.979 45.417  16.738 1.00 20.00 ? 190 LEU A H      1 
ATOM   3614 N N      . TYR B 2 191 ? 57.991 43.954  14.755 1.00 2.01  ? 191 TYR A N      1 
ATOM   3615 C CA     . TYR B 2 191 ? 59.060 43.230  14.045 1.00 2.01  ? 191 TYR A CA     1 
ATOM   3616 C C      . TYR B 2 191 ? 60.169 42.838  15.005 1.00 2.01  ? 191 TYR A C      1 
ATOM   3617 O O      . TYR B 2 191 ? 60.511 43.582  15.901 1.00 2.01  ? 191 TYR A O      1 
ATOM   3618 C CB     . TYR B 2 191 ? 59.692 44.103  12.960 1.00 2.01  ? 191 TYR A CB     1 
ATOM   3619 C CG     . TYR B 2 191 ? 59.038 44.028  11.619 1.00 2.01  ? 191 TYR A CG     1 
ATOM   3620 C CD1    . TYR B 2 191 ? 59.427 43.071  10.713 1.00 2.01  ? 191 TYR A CD1    1 
ATOM   3621 C CD2    . TYR B 2 191 ? 57.999 44.891  11.261 1.00 2.01  ? 191 TYR A CD2    1 
ATOM   3622 C CE1    . TYR B 2 191 ? 58.806 42.952  9.482  1.00 2.00  ? 191 TYR A CE1    1 
ATOM   3623 C CE2    . TYR B 2 191 ? 57.355 44.788  10.023 1.00 2.01  ? 191 TYR A CE2    1 
ATOM   3624 C CZ     . TYR B 2 191 ? 57.768 43.808  9.140  1.00 2.00  ? 191 TYR A CZ     1 
ATOM   3625 O OH     . TYR B 2 191 ? 57.152 43.633  7.907  1.00 2.00  ? 191 TYR A OH     1 
ATOM   3626 H H      . TYR B 2 191 ? 58.239 44.576  15.478 1.00 20.00 ? 191 TYR A H      1 
ATOM   3627 H HH     . TYR B 2 191 ? 56.443 44.284  7.825  1.00 20.00 ? 191 TYR A HH     1 
ATOM   3628 N N      . ARG B 2 192 ? 60.712 41.651  14.813 1.00 2.00  ? 192 ARG A N      1 
ATOM   3629 C CA     . ARG B 2 192 ? 61.810 41.183  15.641 1.00 2.00  ? 192 ARG A CA     1 
ATOM   3630 C C      . ARG B 2 192 ? 62.840 40.530  14.732 1.00 2.01  ? 192 ARG A C      1 
ATOM   3631 O O      . ARG B 2 192 ? 62.485 40.087  13.644 1.00 2.01  ? 192 ARG A O      1 
ATOM   3632 C CB     . ARG B 2 192 ? 61.320 40.220  16.747 1.00 2.01  ? 192 ARG A CB     1 
ATOM   3633 C CG     . ARG B 2 192 ? 59.989 39.442  16.537 1.00 2.01  ? 192 ARG A CG     1 
ATOM   3634 C CD     . ARG B 2 192 ? 60.167 38.303  15.583 1.00 2.00  ? 192 ARG A CD     1 
ATOM   3635 N NE     . ARG B 2 192 ? 59.365 37.131  15.914 1.00 2.00  ? 192 ARG A NE     1 
ATOM   3636 C CZ     . ARG B 2 192 ? 58.281 36.749  15.238 1.00 3.27  ? 192 ARG A CZ     1 
ATOM   3637 N NH1    . ARG B 2 192 ? 57.828 37.495  14.233 1.00 2.00  ? 192 ARG A NH1    1 
ATOM   3638 N NH2    . ARG B 2 192 ? 57.627 35.645  15.590 1.00 4.90  ? 192 ARG A NH2    1 
ATOM   3639 H H      . ARG B 2 192 ? 60.367 41.051  14.095 1.00 20.00 ? 192 ARG A H      1 
ATOM   3640 H HE     . ARG B 2 192 ? 59.631 36.619  16.668 1.00 20.00 ? 192 ARG A HE     1 
ATOM   3641 H HH11   . ARG B 2 192 ? 58.293 38.339  13.964 1.00 20.00 ? 192 ARG A HH11   1 
ATOM   3642 H HH12   . ARG B 2 192 ? 57.017 37.200  13.709 1.00 20.00 ? 192 ARG A HH12   1 
ATOM   3643 H HH21   . ARG B 2 192 ? 57.931 35.117  16.374 1.00 20.00 ? 192 ARG A HH21   1 
ATOM   3644 H HH22   . ARG B 2 192 ? 56.814 35.370  15.079 1.00 20.00 ? 192 ARG A HH22   1 
ATOM   3645 N N      . ILE B 2 193 ? 64.112 40.569  15.118 1.00 2.01  ? 193 ILE A N      1 
ATOM   3646 C CA     . ILE B 2 193 ? 65.174 40.003  14.303 1.00 2.00  ? 193 ILE A CA     1 
ATOM   3647 C C      . ILE B 2 193 ? 65.374 38.517  14.517 1.00 2.01  ? 193 ILE A C      1 
ATOM   3648 O O      . ILE B 2 193 ? 65.532 38.059  15.634 1.00 2.00  ? 193 ILE A O      1 
ATOM   3649 C CB     . ILE B 2 193 ? 66.479 40.702  14.605 1.00 2.54  ? 193 ILE A CB     1 
ATOM   3650 C CG1    . ILE B 2 193 ? 66.337 42.173  14.255 1.00 2.01  ? 193 ILE A CG1    1 
ATOM   3651 C CG2    . ILE B 2 193 ? 67.653 40.040  13.878 1.00 2.00  ? 193 ILE A CG2    1 
ATOM   3652 C CD1    . ILE B 2 193 ? 67.395 43.027  14.946 1.00 2.01  ? 193 ILE A CD1    1 
ATOM   3653 H H      . ILE B 2 193 ? 64.335 40.935  15.990 1.00 20.00 ? 193 ILE A H      1 
ATOM   3654 N N      . LYS B 2 194 ? 65.398 37.762  13.442 1.00 2.00  ? 194 LYS A N      1 
ATOM   3655 C CA     . LYS B 2 194 ? 65.619 36.350  13.531 1.00 2.00  ? 194 LYS A CA     1 
ATOM   3656 C C      . LYS B 2 194 ? 66.428 35.998  12.318 1.00 2.00  ? 194 LYS A C      1 
ATOM   3657 O O      . LYS B 2 194 ? 65.969 36.217  11.199 1.00 2.00  ? 194 LYS A O      1 
ATOM   3658 C CB     . LYS B 2 194 ? 64.286 35.623  13.501 1.00 2.01  ? 194 LYS A CB     1 
ATOM   3659 C CG     . LYS B 2 194 ? 63.856 35.136  14.848 1.00 2.01  ? 194 LYS A CG     1 
ATOM   3660 C CD     . LYS B 2 194 ? 62.346 35.139  14.960 1.00 2.00  ? 194 LYS A CD     1 
ATOM   3661 C CE     . LYS B 2 194 ? 61.835 34.193  16.052 1.00 2.01  ? 194 LYS A CE     1 
ATOM   3662 N NZ     . LYS B 2 194 ? 62.318 34.574  17.393 1.00 2.00  ? 194 LYS A NZ     1 
ATOM   3663 H H      . LYS B 2 194 ? 65.261 38.143  12.572 1.00 20.00 ? 194 LYS A H      1 
ATOM   3664 H HZ1    . LYS B 2 194 ? 62.170 35.598  17.494 1.00 20.00 ? 194 LYS A HZ1    1 
ATOM   3665 H HZ2    . LYS B 2 194 ? 61.751 34.071  18.107 1.00 20.00 ? 194 LYS A HZ2    1 
ATOM   3666 H HZ3    . LYS B 2 194 ? 63.314 34.339  17.491 1.00 20.00 ? 194 LYS A HZ3    1 
ATOM   3667 N N      . PHE B 2 195 ? 67.690 35.629  12.534 1.00 3.81  ? 195 PHE A N      1 
ATOM   3668 C CA     . PHE B 2 195 ? 68.565 35.211  11.443 1.00 2.44  ? 195 PHE A CA     1 
ATOM   3669 C C      . PHE B 2 195 ? 68.308 33.705  11.294 1.00 3.21  ? 195 PHE A C      1 
ATOM   3670 O O      . PHE B 2 195 ? 69.086 32.877  11.761 1.00 2.77  ? 195 PHE A O      1 
ATOM   3671 C CB     . PHE B 2 195 ? 70.019 35.456  11.807 1.00 2.01  ? 195 PHE A CB     1 
ATOM   3672 C CG     . PHE B 2 195 ? 70.369 36.886  11.932 1.00 2.00  ? 195 PHE A CG     1 
ATOM   3673 C CD1    . PHE B 2 195 ? 70.421 37.697  10.818 1.00 2.01  ? 195 PHE A CD1    1 
ATOM   3674 C CD2    . PHE B 2 195 ? 70.686 37.420  13.166 1.00 2.00  ? 195 PHE A CD2    1 
ATOM   3675 C CE1    . PHE B 2 195 ? 70.789 39.029  10.937 1.00 2.00  ? 195 PHE A CE1    1 
ATOM   3676 C CE2    . PHE B 2 195 ? 71.054 38.753  13.301 1.00 2.00  ? 195 PHE A CE2    1 
ATOM   3677 C CZ     . PHE B 2 195 ? 71.108 39.558  12.188 1.00 2.00  ? 195 PHE A CZ     1 
ATOM   3678 H H      . PHE B 2 195 ? 68.058 35.617  13.444 1.00 20.00 ? 195 PHE A H      1 
ATOM   3679 N N      . ALA B 2 196 ? 67.163 33.361  10.726 1.00 6.54  ? 196 ALA A N      1 
ATOM   3680 C CA     . ALA B 2 196 ? 66.790 31.970  10.552 1.00 8.16  ? 196 ALA A CA     1 
ATOM   3681 C C      . ALA B 2 196 ? 66.210 31.810  9.165  1.00 10.73 ? 196 ALA A C      1 
ATOM   3682 O O      . ALA B 2 196 ? 65.453 32.674  8.711  1.00 9.92  ? 196 ALA A O      1 
ATOM   3683 C CB     . ALA B 2 196 ? 65.768 31.571  11.595 1.00 9.33  ? 196 ALA A CB     1 
ATOM   3684 H H      . ALA B 2 196 ? 66.542 34.057  10.407 1.00 20.00 ? 196 ALA A H      1 
ATOM   3685 N N      . GLU B 2 197 ? 66.593 30.725  8.497  1.00 13.89 ? 197 GLU A N      1 
ATOM   3686 C CA     . GLU B 2 197 ? 66.132 30.418  7.151  1.00 14.74 ? 197 GLU A CA     1 
ATOM   3687 C C      . GLU B 2 197 ? 64.637 30.147  7.262  1.00 9.95  ? 197 GLU A C      1 
ATOM   3688 O O      . GLU B 2 197 ? 64.204 29.392  8.128  1.00 10.80 ? 197 GLU A O      1 
ATOM   3689 C CB     . GLU B 2 197 ? 66.863 29.176  6.655  1.00 21.66 ? 197 GLU A CB     1 
ATOM   3690 C CG     . GLU B 2 197 ? 66.972 29.026  5.167  1.00 30.82 ? 197 GLU A CG     1 
ATOM   3691 C CD     . GLU B 2 197 ? 67.844 27.838  4.813  1.00 34.57 ? 197 GLU A CD     1 
ATOM   3692 O OE1    . GLU B 2 197 ? 69.084 27.996  4.742  1.00 37.00 ? 197 GLU A OE1    1 
ATOM   3693 O OE2    . GLU B 2 197 ? 67.288 26.730  4.635  1.00 38.14 ? 197 GLU A OE2    1 
ATOM   3694 H H      . GLU B 2 197 ? 67.208 30.105  8.923  1.00 20.00 ? 197 GLU A H      1 
ATOM   3695 N N      . HIS B 2 198 ? 63.841 30.796  6.426  1.00 4.02  ? 198 HIS A N      1 
ATOM   3696 C CA     . HIS B 2 198 ? 62.402 30.627  6.438  1.00 2.05  ? 198 HIS A CA     1 
ATOM   3697 C C      . HIS B 2 198 ? 62.047 29.570  5.418  1.00 2.00  ? 198 HIS A C      1 
ATOM   3698 O O      . HIS B 2 198 ? 62.530 29.628  4.312  1.00 2.00  ? 198 HIS A O      1 
ATOM   3699 C CB     . HIS B 2 198 ? 61.739 31.947  6.068  1.00 2.00  ? 198 HIS A CB     1 
ATOM   3700 C CG     . HIS B 2 198 ? 60.248 31.922  6.211  1.00 2.00  ? 198 HIS A CG     1 
ATOM   3701 N ND1    . HIS B 2 198 ? 59.415 31.473  5.222  1.00 2.00  ? 198 HIS A ND1    1 
ATOM   3702 C CD2    . HIS B 2 198 ? 59.459 32.272  7.256  1.00 2.00  ? 198 HIS A CD2    1 
ATOM   3703 C CE1    . HIS B 2 198 ? 58.160 31.533  5.644  1.00 2.55  ? 198 HIS A CE1    1 
ATOM   3704 N NE2    . HIS B 2 198 ? 58.164 32.012  6.871  1.00 2.66  ? 198 HIS A NE2    1 
ATOM   3705 H H      . HIS B 2 198 ? 64.204 31.436  5.841  1.00 20.00 ? 198 HIS A H      1 
ATOM   3706 H HD1    . HIS B 2 198 ? 59.665 31.200  4.341  1.00 20.00 ? 198 HIS A HD1    1 
ATOM   3707 H HE2    . HIS B 2 198 ? 57.358 32.168  7.450  1.00 20.00 ? 198 HIS A HE2    1 
ATOM   3708 N N      . HIS B 2 199 ? 61.093 28.697  5.718  1.00 2.19  ? 199 HIS A N      1 
ATOM   3709 C CA     . HIS B 2 199 ? 60.758 27.610  4.792  1.00 2.01  ? 199 HIS A CA     1 
ATOM   3710 C C      . HIS B 2 199 ? 60.170 28.013  3.464  1.00 2.01  ? 199 HIS A C      1 
ATOM   3711 O O      . HIS B 2 199 ? 59.932 27.174  2.636  1.00 2.00  ? 199 HIS A O      1 
ATOM   3712 C CB     . HIS B 2 199 ? 59.847 26.585  5.468  1.00 2.01  ? 199 HIS A CB     1 
ATOM   3713 C CG     . HIS B 2 199 ? 58.602 27.168  6.052  1.00 2.01  ? 199 HIS A CG     1 
ATOM   3714 N ND1    . HIS B 2 199 ? 57.428 27.276  5.341  1.00 2.01  ? 199 HIS A ND1    1 
ATOM   3715 C CD2    . HIS B 2 199 ? 58.339 27.642  7.287  1.00 2.01  ? 199 HIS A CD2    1 
ATOM   3716 C CE1    . HIS B 2 199 ? 56.491 27.792  6.119  1.00 2.01  ? 199 HIS A CE1    1 
ATOM   3717 N NE2    . HIS B 2 199 ? 57.019 28.025  7.305  1.00 2.01  ? 199 HIS A NE2    1 
ATOM   3718 H H      . HIS B 2 199 ? 60.662 28.754  6.586  1.00 20.00 ? 199 HIS A H      1 
ATOM   3719 H HD1    . HIS B 2 199 ? 57.309 26.987  4.410  1.00 20.00 ? 199 HIS A HD1    1 
ATOM   3720 H HE2    . HIS B 2 199 ? 56.551 28.392  8.080  1.00 20.00 ? 199 HIS A HE2    1 
ATOM   3721 N N      . GLN B 2 200 ? 59.853 29.285  3.286  1.00 2.44  ? 200 GLN A N      1 
ATOM   3722 C CA     . GLN B 2 200 ? 59.291 29.742  2.020  1.00 2.00  ? 200 GLN A CA     1 
ATOM   3723 C C      . GLN B 2 200 ? 60.210 30.787  1.413  1.00 2.59  ? 200 GLN A C      1 
ATOM   3724 O O      . GLN B 2 200 ? 60.555 30.705  0.250  1.00 3.11  ? 200 GLN A O      1 
ATOM   3725 C CB     . GLN B 2 200 ? 57.922 30.370  2.231  1.00 2.01  ? 200 GLN A CB     1 
ATOM   3726 C CG     . GLN B 2 200 ? 56.904 29.415  2.732  1.00 2.00  ? 200 GLN A CG     1 
ATOM   3727 C CD     . GLN B 2 200 ? 56.576 28.378  1.705  1.00 2.00  ? 200 GLN A CD     1 
ATOM   3728 O OE1    . GLN B 2 200 ? 56.417 28.707  0.540  1.00 2.01  ? 200 GLN A OE1    1 
ATOM   3729 N NE2    . GLN B 2 200 ? 56.460 27.112  2.132  1.00 2.25  ? 200 GLN A NE2    1 
ATOM   3730 H H      . GLN B 2 200 ? 60.071 29.896  3.972  1.00 20.00 ? 200 GLN A H      1 
ATOM   3731 H HE21   . GLN B 2 200 ? 56.266 26.418  1.447  1.00 20.00 ? 200 GLN A HE21   1 
ATOM   3732 H HE22   . GLN B 2 200 ? 56.587 26.874  3.046  1.00 20.00 ? 200 GLN A HE22   1 
ATOM   3733 N N      . THR B 2 201 ? 60.617 31.761  2.217  1.00 4.53  ? 201 THR A N      1 
ATOM   3734 C CA     . THR B 2 201 ? 61.471 32.847  1.744  1.00 6.88  ? 201 THR A CA     1 
ATOM   3735 C C      . THR B 2 201 ? 62.964 32.634  1.968  1.00 5.86  ? 201 THR A C      1 
ATOM   3736 O O      . THR B 2 201 ? 63.748 33.577  1.845  1.00 7.27  ? 201 THR A O      1 
ATOM   3737 C CB     . THR B 2 201 ? 61.029 34.239  2.333  1.00 10.06 ? 201 THR A CB     1 
ATOM   3738 O OG1    . THR B 2 201 ? 60.993 34.194  3.767  1.00 9.87  ? 201 THR A OG1    1 
ATOM   3739 C CG2    . THR B 2 201 ? 59.642 34.609  1.827  1.00 9.21  ? 201 THR A CG2    1 
ATOM   3740 H H      . THR B 2 201 ? 60.371 31.773  3.138  1.00 20.00 ? 201 THR A H      1 
ATOM   3741 H HG1    . THR B 2 201 ? 60.753 35.050  4.128  1.00 20.00 ? 201 THR A HG1    1 
ATOM   3742 N N      . GLY B 2 202 ? 63.357 31.411  2.314  1.00 7.20  ? 202 GLY A N      1 
ATOM   3743 C CA     . GLY B 2 202 ? 64.762 31.099  2.512  1.00 7.66  ? 202 GLY A CA     1 
ATOM   3744 C C      . GLY B 2 202 ? 65.490 32.055  3.423  1.00 9.19  ? 202 GLY A C      1 
ATOM   3745 O O      . GLY B 2 202 ? 65.199 32.107  4.593  1.00 9.38  ? 202 GLY A O      1 
ATOM   3746 H H      . GLY B 2 202 ? 62.698 30.711  2.443  1.00 20.00 ? 202 GLY A H      1 
ATOM   3747 N N      . ASN B 2 203 ? 66.440 32.813  2.896  1.00 11.31 ? 203 ASN A N      1 
ATOM   3748 C CA     . ASN B 2 203 ? 67.191 33.762  3.718  1.00 13.02 ? 203 ASN A CA     1 
ATOM   3749 C C      . ASN B 2 203 ? 66.956 35.189  3.268  1.00 9.50  ? 203 ASN A C      1 
ATOM   3750 O O      . ASN B 2 203 ? 67.743 36.076  3.574  1.00 8.16  ? 203 ASN A O      1 
ATOM   3751 C CB     . ASN B 2 203 ? 68.687 33.473  3.631  1.00 18.76 ? 203 ASN A CB     1 
ATOM   3752 C CG     . ASN B 2 203 ? 69.039 32.083  4.093  1.00 25.76 ? 203 ASN A CG     1 
ATOM   3753 O OD1    . ASN B 2 203 ? 68.765 31.710  5.242  1.00 27.04 ? 203 ASN A OD1    1 
ATOM   3754 N ND2    . ASN B 2 203 ? 69.615 31.284  3.188  1.00 29.71 ? 203 ASN A ND2    1 
ATOM   3755 H H      . ASN B 2 203 ? 66.645 32.724  1.964  1.00 20.00 ? 203 ASN A H      1 
ATOM   3756 H HD21   . ASN B 2 203 ? 69.830 30.378  3.466  1.00 20.00 ? 203 ASN A HD21   1 
ATOM   3757 H HD22   . ASN B 2 203 ? 69.779 31.635  2.288  1.00 20.00 ? 203 ASN A HD22   1 
ATOM   3758 N N      . LYS B 2 204 ? 65.918 35.389  2.466  1.00 6.69  ? 204 LYS A N      1 
ATOM   3759 C CA     . LYS B 2 204 ? 65.598 36.719  1.954  1.00 5.03  ? 204 LYS A CA     1 
ATOM   3760 C C      . LYS B 2 204 ? 65.397 37.672  3.122  1.00 4.93  ? 204 LYS A C      1 
ATOM   3761 O O      . LYS B 2 204 ? 65.822 38.809  3.062  1.00 4.76  ? 204 LYS A O      1 
ATOM   3762 C CB     . LYS B 2 204 ? 64.327 36.663  1.095  1.00 7.21  ? 204 LYS A CB     1 
ATOM   3763 C CG     . LYS B 2 204 ? 63.840 38.031  0.596  1.00 11.20 ? 204 LYS A CG     1 
ATOM   3764 C CD     . LYS B 2 204 ? 62.442 37.995  -0.126 1.00 17.42 ? 204 LYS A CD     1 
ATOM   3765 C CE     . LYS B 2 204 ? 62.017 39.443  -0.603 1.00 21.58 ? 204 LYS A CE     1 
ATOM   3766 N NZ     . LYS B 2 204 ? 60.680 39.558  -1.233 1.00 24.75 ? 204 LYS A NZ     1 
ATOM   3767 H H      . LYS B 2 204 ? 65.303 34.642  2.283  1.00 20.00 ? 204 LYS A H      1 
ATOM   3768 H HZ1    . LYS B 2 204 ? 59.974 39.034  -0.671 1.00 20.00 ? 204 LYS A HZ1    1 
ATOM   3769 H HZ2    . LYS B 2 204 ? 60.398 40.539  -1.338 1.00 20.00 ? 204 LYS A HZ2    1 
ATOM   3770 H HZ3    . LYS B 2 204 ? 60.679 39.112  -2.205 1.00 20.00 ? 204 LYS A HZ3    1 
ATOM   3771 N N      . TRP B 2 205 ? 64.783 37.183  4.196  1.00 5.47  ? 205 TRP A N      1 
ATOM   3772 C CA     . TRP B 2 205 ? 64.523 38.032  5.350  1.00 3.04  ? 205 TRP A CA     1 
ATOM   3773 C C      . TRP B 2 205 ? 65.240 37.665  6.657  1.00 4.28  ? 205 TRP A C      1 
ATOM   3774 O O      . TRP B 2 205 ? 65.509 36.483  6.935  1.00 7.72  ? 205 TRP A O      1 
ATOM   3775 C CB     . TRP B 2 205 ? 63.033 38.045  5.645  1.00 2.00  ? 205 TRP A CB     1 
ATOM   3776 C CG     . TRP B 2 205 ? 62.165 38.566  4.548  1.00 2.00  ? 205 TRP A CG     1 
ATOM   3777 C CD1    . TRP B 2 205 ? 61.546 37.841  3.577  1.00 2.79  ? 205 TRP A CD1    1 
ATOM   3778 C CD2    . TRP B 2 205 ? 61.821 39.933  4.307  1.00 2.01  ? 205 TRP A CD2    1 
ATOM   3779 N NE1    . TRP B 2 205 ? 60.835 38.667  2.754  1.00 2.00  ? 205 TRP A NE1    1 
ATOM   3780 C CE2    . TRP B 2 205 ? 60.981 39.957  3.187  1.00 2.00  ? 205 TRP A CE2    1 
ATOM   3781 C CE3    . TRP B 2 205 ? 62.123 41.141  4.955  1.00 2.00  ? 205 TRP A CE3    1 
ATOM   3782 C CZ2    . TRP B 2 205 ? 60.461 41.141  2.673  1.00 2.01  ? 205 TRP A CZ2    1 
ATOM   3783 C CZ3    . TRP B 2 205 ? 61.599 42.318  4.446  1.00 2.01  ? 205 TRP A CZ3    1 
ATOM   3784 C CH2    . TRP B 2 205 ? 60.766 42.304  3.324  1.00 2.01  ? 205 TRP A CH2    1 
ATOM   3785 H H      . TRP B 2 205 ? 64.519 36.235  4.249  1.00 20.00 ? 205 TRP A H      1 
ATOM   3786 H HE1    . TRP B 2 205 ? 60.307 38.362  1.990  1.00 20.00 ? 205 TRP A HE1    1 
ATOM   3787 N N      . CYS B 2 206 ? 65.525 38.681  7.478  1.00 6.46  ? 206 CYS A N      1 
ATOM   3788 C CA     . CYS B 2 206 ? 66.099 38.418  8.789  1.00 5.51  ? 206 CYS A CA     1 
ATOM   3789 C C      . CYS B 2 206 ? 65.313 39.142  9.865  1.00 3.71  ? 206 CYS A C      1 
ATOM   3790 O O      . CYS B 2 206 ? 65.615 39.001  11.038 1.00 3.02  ? 206 CYS A O      1 
ATOM   3791 C CB     . CYS B 2 206 ? 67.599 38.662  8.889  1.00 7.22  ? 206 CYS A CB     1 
ATOM   3792 S SG     . CYS B 2 206 ? 68.068 40.326  8.945  1.00 10.95 ? 206 CYS A SG     1 
ATOM   3793 H H      . CYS B 2 206 ? 65.394 39.587  7.182  1.00 20.00 ? 206 CYS A H      1 
ATOM   3794 N N      . ILE B 2 207 ? 64.301 39.911  9.461  1.00 2.37  ? 207 ILE A N      1 
ATOM   3795 C CA     . ILE B 2 207 ? 63.378 40.546  10.409 1.00 2.00  ? 207 ILE A CA     1 
ATOM   3796 C C      . ILE B 2 207 ? 62.007 39.949  10.043 1.00 2.00  ? 207 ILE A C      1 
ATOM   3797 O O      . ILE B 2 207 ? 61.669 39.878  8.862  1.00 2.00  ? 207 ILE A O      1 
ATOM   3798 C CB     . ILE B 2 207 ? 63.331 42.089  10.308 1.00 2.01  ? 207 ILE A CB     1 
ATOM   3799 C CG1    . ILE B 2 207 ? 62.667 42.543  9.004  1.00 2.01  ? 207 ILE A CG1    1 
ATOM   3800 C CG2    . ILE B 2 207 ? 64.722 42.635  10.416 1.00 2.01  ? 207 ILE A CG2    1 
ATOM   3801 C CD1    . ILE B 2 207 ? 62.587 44.008  8.833  1.00 2.01  ? 207 ILE A CD1    1 
ATOM   3802 H H      . ILE B 2 207 ? 64.168 40.041  8.511  1.00 20.00 ? 207 ILE A H      1 
ATOM   3803 N N      . TYR B 2 208 ? 61.261 39.441  11.021 1.00 2.01  ? 208 TYR A N      1 
ATOM   3804 C CA     . TYR B 2 208 ? 59.953 38.818  10.779 1.00 2.01  ? 208 TYR A CA     1 
ATOM   3805 C C      . TYR B 2 208 ? 58.819 39.495  11.574 1.00 2.00  ? 208 TYR A C      1 
ATOM   3806 O O      . TYR B 2 208 ? 58.990 39.862  12.740 1.00 2.00  ? 208 TYR A O      1 
ATOM   3807 C CB     . TYR B 2 208 ? 60.023 37.339  11.117 1.00 2.01  ? 208 TYR A CB     1 
ATOM   3808 C CG     . TYR B 2 208 ? 60.958 36.569  10.231 1.00 2.01  ? 208 TYR A CG     1 
ATOM   3809 C CD1    . TYR B 2 208 ? 60.509 36.028  9.043  1.00 2.01  ? 208 TYR A CD1    1 
ATOM   3810 C CD2    . TYR B 2 208 ? 62.292 36.399  10.566 1.00 2.01  ? 208 TYR A CD2    1 
ATOM   3811 C CE1    . TYR B 2 208 ? 61.351 35.343  8.213  1.00 2.00  ? 208 TYR A CE1    1 
ATOM   3812 C CE2    . TYR B 2 208 ? 63.140 35.723  9.743  1.00 2.01  ? 208 TYR A CE2    1 
ATOM   3813 C CZ     . TYR B 2 208 ? 62.661 35.193  8.563  1.00 2.01  ? 208 TYR A CZ     1 
ATOM   3814 O OH     . TYR B 2 208 ? 63.468 34.493  7.694  1.00 4.30  ? 208 TYR A OH     1 
ATOM   3815 H H      . TYR B 2 208 ? 61.553 39.563  11.942 1.00 20.00 ? 208 TYR A H      1 
ATOM   3816 H HH     . TYR B 2 208 ? 64.399 34.449  8.060  1.00 20.00 ? 208 TYR A HH     1 
ATOM   3817 N N      . PRO B 2 209 ? 57.643 39.695  10.949 1.00 2.01  ? 209 PRO A N      1 
ATOM   3818 C CA     . PRO B 2 209 ? 56.463 40.327  11.534 1.00 2.01  ? 209 PRO A CA     1 
ATOM   3819 C C      . PRO B 2 209 ? 55.806 39.466  12.566 1.00 2.01  ? 209 PRO A C      1 
ATOM   3820 O O      . PRO B 2 209 ? 55.756 38.262  12.405 1.00 2.00  ? 209 PRO A O      1 
ATOM   3821 C CB     . PRO B 2 209 ? 55.560 40.502  10.329 1.00 2.01  ? 209 PRO A CB     1 
ATOM   3822 C CG     . PRO B 2 209 ? 55.838 39.316  9.553  1.00 2.01  ? 209 PRO A CG     1 
ATOM   3823 C CD     . PRO B 2 209 ? 57.344 39.294  9.567  1.00 2.00  ? 209 PRO A CD     1 
ATOM   3824 N N      . MET B 2 210 ? 55.237 40.099  13.582 1.00 2.01  ? 210 MET A N      1 
ATOM   3825 C CA     . MET B 2 210 ? 54.577 39.385  14.650 1.00 2.01  ? 210 MET A CA     1 
ATOM   3826 C C      . MET B 2 210 ? 53.169 39.051  14.223 1.00 2.01  ? 210 MET A C      1 
ATOM   3827 O O      . MET B 2 210 ? 52.618 39.684  13.339 1.00 2.01  ? 210 MET A O      1 
ATOM   3828 C CB     . MET B 2 210 ? 54.512 40.247  15.899 1.00 2.02  ? 210 MET A CB     1 
ATOM   3829 C CG     . MET B 2 210 ? 55.836 40.605  16.473 1.00 2.00  ? 210 MET A CG     1 
ATOM   3830 S SD     . MET B 2 210 ? 56.643 39.228  17.208 1.00 2.02  ? 210 MET A SD     1 
ATOM   3831 C CE     . MET B 2 210 ? 55.680 39.046  18.646 1.00 2.02  ? 210 MET A CE     1 
ATOM   3832 H H      . MET B 2 210 ? 55.286 41.064  13.607 1.00 20.00 ? 210 MET A H      1 
ATOM   3833 N N      . TYR B 2 211 ? 52.545 38.123  14.938 1.00 4.60  ? 211 TYR A N      1 
ATOM   3834 C CA     . TYR B 2 211 ? 51.199 37.714  14.628 1.00 2.01  ? 211 TYR A CA     1 
ATOM   3835 C C      . TYR B 2 211 ? 50.255 38.890  14.512 1.00 2.01  ? 211 TYR A C      1 
ATOM   3836 O O      . TYR B 2 211 ? 49.698 39.083  13.458 1.00 2.00  ? 211 TYR A O      1 
ATOM   3837 C CB     . TYR B 2 211 ? 50.678 36.711  15.655 1.00 2.01  ? 211 TYR A CB     1 
ATOM   3838 C CG     . TYR B 2 211 ? 49.172 36.563  15.675 1.00 2.01  ? 211 TYR A CG     1 
ATOM   3839 C CD1    . TYR B 2 211 ? 48.504 35.671  14.836 1.00 2.01  ? 211 TYR A CD1    1 
ATOM   3840 C CD2    . TYR B 2 211 ? 48.416 37.360  16.492 1.00 2.01  ? 211 TYR A CD2    1 
ATOM   3841 C CE1    . TYR B 2 211 ? 47.129 35.603  14.827 1.00 2.01  ? 211 TYR A CE1    1 
ATOM   3842 C CE2    . TYR B 2 211 ? 47.073 37.305  16.492 1.00 2.00  ? 211 TYR A CE2    1 
ATOM   3843 C CZ     . TYR B 2 211 ? 46.421 36.436  15.668 1.00 2.01  ? 211 TYR A CZ     1 
ATOM   3844 O OH     . TYR B 2 211 ? 45.050 36.437  15.720 1.00 2.00  ? 211 TYR A OH     1 
ATOM   3845 H H      . TYR B 2 211 ? 52.999 37.711  15.712 1.00 20.00 ? 211 TYR A H      1 
ATOM   3846 H HH     . TYR B 2 211 ? 44.730 37.087  16.342 1.00 20.00 ? 211 TYR A HH     1 
ATOM   3847 N N      . ASP B 2 212 ? 50.119 39.724  15.541 1.00 2.01  ? 212 ASP A N      1 
ATOM   3848 C CA     . ASP B 2 212 ? 49.156 40.821  15.470 1.00 2.01  ? 212 ASP A CA     1 
ATOM   3849 C C      . ASP B 2 212 ? 49.300 41.805  14.334 1.00 2.01  ? 212 ASP A C      1 
ATOM   3850 O O      . ASP B 2 212 ? 48.308 42.318  13.835 1.00 2.00  ? 212 ASP A O      1 
ATOM   3851 C CB     . ASP B 2 212 ? 49.016 41.558  16.799 1.00 2.01  ? 212 ASP A CB     1 
ATOM   3852 C CG     . ASP B 2 212 ? 48.467 40.683  17.895 1.00 2.01  ? 212 ASP A CG     1 
ATOM   3853 O OD1    . ASP B 2 212 ? 47.239 40.484  17.981 1.00 2.01  ? 212 ASP A OD1    1 
ATOM   3854 O OD2    . ASP B 2 212 ? 49.272 40.162  18.667 1.00 2.01  ? 212 ASP A OD2    1 
ATOM   3855 H H      . ASP B 2 212 ? 50.633 39.599  16.342 1.00 20.00 ? 212 ASP A H      1 
ATOM   3856 N N      . PHE B 2 213 ? 50.523 42.094  13.934 1.00 2.01  ? 213 PHE A N      1 
ATOM   3857 C CA     . PHE B 2 213 ? 50.713 42.973  12.808 1.00 2.02  ? 213 PHE A CA     1 
ATOM   3858 C C      . PHE B 2 213 ? 50.342 42.237  11.502 1.00 2.00  ? 213 PHE A C      1 
ATOM   3859 O O      . PHE B 2 213 ? 49.599 42.764  10.685 1.00 2.01  ? 213 PHE A O      1 
ATOM   3860 C CB     . PHE B 2 213 ? 52.163 43.439  12.754 1.00 2.01  ? 213 PHE A CB     1 
ATOM   3861 C CG     . PHE B 2 213 ? 52.440 44.474  11.704 1.00 2.01  ? 213 PHE A CG     1 
ATOM   3862 C CD1    . PHE B 2 213 ? 51.750 45.688  11.680 1.00 2.02  ? 213 PHE A CD1    1 
ATOM   3863 C CD2    . PHE B 2 213 ? 53.416 44.241  10.756 1.00 2.01  ? 213 PHE A CD2    1 
ATOM   3864 C CE1    . PHE B 2 213 ? 52.030 46.646  10.727 1.00 2.01  ? 213 PHE A CE1    1 
ATOM   3865 C CE2    . PHE B 2 213 ? 53.706 45.190  9.796  1.00 2.00  ? 213 PHE A CE2    1 
ATOM   3866 C CZ     . PHE B 2 213 ? 53.008 46.402  9.784  1.00 2.01  ? 213 PHE A CZ     1 
ATOM   3867 H H      . PHE B 2 213 ? 51.285 41.710  14.403 1.00 20.00 ? 213 PHE A H      1 
ATOM   3868 N N      . THR B 2 214 ? 50.770 40.984  11.356 1.00 2.01  ? 214 THR A N      1 
ATOM   3869 C CA     . THR B 2 214 ? 50.520 40.193  10.149 1.00 2.01  ? 214 THR A CA     1 
ATOM   3870 C C      . THR B 2 214 ? 49.061 39.806  9.854  1.00 2.01  ? 214 THR A C      1 
ATOM   3871 O O      . THR B 2 214 ? 48.551 39.909  8.733  1.00 2.00  ? 214 THR A O      1 
ATOM   3872 C CB     . THR B 2 214 ? 51.316 38.866  10.193 1.00 2.01  ? 214 THR A CB     1 
ATOM   3873 O OG1    . THR B 2 214 ? 52.682 39.126  10.469 1.00 2.00  ? 214 THR A OG1    1 
ATOM   3874 C CG2    . THR B 2 214 ? 51.272 38.190  8.889  1.00 2.01  ? 214 THR A CG2    1 
ATOM   3875 H H      . THR B 2 214 ? 51.294 40.595  12.069 1.00 20.00 ? 214 THR A H      1 
ATOM   3876 H HG1    . THR B 2 214 ? 53.150 38.328  10.519 1.00 20.00 ? 214 THR A HG1    1 
ATOM   3877 N N      . HIS B 2 215 ? 48.384 39.324  10.863 1.00 2.01  ? 215 HIS A N      1 
ATOM   3878 C CA     . HIS B 2 215 ? 47.046 38.846  10.659 1.00 2.01  ? 215 HIS A CA     1 
ATOM   3879 C C      . HIS B 2 215 ? 45.936 39.744  10.152 1.00 2.01  ? 215 HIS A C      1 
ATOM   3880 O O      . HIS B 2 215 ? 45.075 39.286  9.414  1.00 2.01  ? 215 HIS A O      1 
ATOM   3881 C CB     . HIS B 2 215 ? 46.592 38.149  11.906 1.00 2.01  ? 215 HIS A CB     1 
ATOM   3882 C CG     . HIS B 2 215 ? 45.761 36.951  11.635 1.00 2.00  ? 215 HIS A CG     1 
ATOM   3883 N ND1    . HIS B 2 215 ? 44.389 37.015  11.588 1.00 2.00  ? 215 HIS A ND1    1 
ATOM   3884 C CD2    . HIS B 2 215 ? 46.093 35.668  11.374 1.00 2.00  ? 215 HIS A CD2    1 
ATOM   3885 C CE1    . HIS B 2 215 ? 43.910 35.817  11.310 1.00 3.95  ? 215 HIS A CE1    1 
ATOM   3886 N NE2    . HIS B 2 215 ? 44.926 34.979  11.174 1.00 2.00  ? 215 HIS A NE2    1 
ATOM   3887 H H      . HIS B 2 215 ? 48.788 39.313  11.762 1.00 20.00 ? 215 HIS A H      1 
ATOM   3888 H HD1    . HIS B 2 215 ? 43.835 37.825  11.717 1.00 20.00 ? 215 HIS A HD1    1 
ATOM   3889 H HE2    . HIS B 2 215 ? 44.847 34.020  10.995 1.00 20.00 ? 215 HIS A HE2    1 
ATOM   3890 N N      . CYS B 2 216 ? 45.870 40.981  10.608 1.00 2.01  ? 216 CYS A N      1 
ATOM   3891 C CA     . CYS B 2 216 ? 44.805 41.861  10.178 1.00 2.01  ? 216 CYS A CA     1 
ATOM   3892 C C      . CYS B 2 216 ? 45.082 42.360  8.785  1.00 2.01  ? 216 CYS A C      1 
ATOM   3893 O O      . CYS B 2 216 ? 44.184 42.434  7.934  1.00 2.00  ? 216 CYS A O      1 
ATOM   3894 C CB     . CYS B 2 216 ? 44.705 43.030  11.137 1.00 2.87  ? 216 CYS A CB     1 
ATOM   3895 S SG     . CYS B 2 216 ? 46.305 43.889  11.303 1.00 7.21  ? 216 CYS A SG     1 
ATOM   3896 H H      . CYS B 2 216 ? 46.521 41.289  11.280 1.00 20.00 ? 216 CYS A H      1 
ATOM   3897 N N      . ILE B 2 217 ? 46.331 42.718  8.539  1.00 2.01  ? 217 ILE A N      1 
ATOM   3898 C CA     . ILE B 2 217 ? 46.716 43.164  7.212  1.00 2.01  ? 217 ILE A CA     1 
ATOM   3899 C C      . ILE B 2 217 ? 46.491 42.060  6.173  1.00 2.01  ? 217 ILE A C      1 
ATOM   3900 O O      . ILE B 2 217 ? 45.970 42.333  5.096  1.00 2.01  ? 217 ILE A O      1 
ATOM   3901 C CB     . ILE B 2 217 ? 48.136 43.689  7.209  1.00 2.01  ? 217 ILE A CB     1 
ATOM   3902 C CG1    . ILE B 2 217 ? 48.155 44.971  8.029  1.00 2.01  ? 217 ILE A CG1    1 
ATOM   3903 C CG2    . ILE B 2 217 ? 48.634 43.883  5.794  1.00 2.01  ? 217 ILE A CG2    1 
ATOM   3904 C CD1    . ILE B 2 217 ? 49.471 45.597  8.133  1.00 2.00  ? 217 ILE A CD1    1 
ATOM   3905 H H      . ILE B 2 217 ? 46.991 42.708  9.258  1.00 20.00 ? 217 ILE A H      1 
ATOM   3906 N N      . SER B 2 218 ? 46.834 40.814  6.492  1.00 2.01  ? 218 SER A N      1 
ATOM   3907 C CA     . SER B 2 218 ? 46.601 39.696  5.579  1.00 2.00  ? 218 SER A CA     1 
ATOM   3908 C C      . SER B 2 218 ? 45.106 39.494  5.321  1.00 2.01  ? 218 SER A C      1 
ATOM   3909 O O      . SER B 2 218 ? 44.713 39.236  4.206  1.00 2.00  ? 218 SER A O      1 
ATOM   3910 C CB     . SER B 2 218 ? 47.202 38.434  6.149  1.00 2.01  ? 218 SER A CB     1 
ATOM   3911 O OG     . SER B 2 218 ? 48.555 38.685  6.396  1.00 2.01  ? 218 SER A OG     1 
ATOM   3912 H H      . SER B 2 218 ? 47.232 40.621  7.363  1.00 20.00 ? 218 SER A H      1 
ATOM   3913 H HG     . SER B 2 218 ? 48.910 37.785  6.731  1.00 20.00 ? 218 SER A HG     1 
ATOM   3914 N N      . ASP B 2 219 ? 44.264 39.583  6.341  1.00 2.01  ? 219 ASP A N      1 
ATOM   3915 C CA     . ASP B 2 219 ? 42.827 39.418  6.155  1.00 2.01  ? 219 ASP A CA     1 
ATOM   3916 C C      . ASP B 2 219 ? 42.285 40.518  5.253  1.00 2.01  ? 219 ASP A C      1 
ATOM   3917 O O      . ASP B 2 219 ? 41.422 40.253  4.403  1.00 2.01  ? 219 ASP A O      1 
ATOM   3918 C CB     . ASP B 2 219 ? 42.111 39.485  7.492  1.00 2.00  ? 219 ASP A CB     1 
ATOM   3919 C CG     . ASP B 2 219 ? 42.263 38.232  8.304  1.00 2.02  ? 219 ASP A CG     1 
ATOM   3920 O OD1    . ASP B 2 219 ? 42.356 37.118  7.722  1.00 2.00  ? 219 ASP A OD1    1 
ATOM   3921 O OD2    . ASP B 2 219 ? 42.274 38.385  9.546  1.00 2.00  ? 219 ASP A OD2    1 
ATOM   3922 H H      . ASP B 2 219 ? 44.613 39.773  7.223  1.00 20.00 ? 219 ASP A H      1 
ATOM   3923 N N      . ALA B 2 220 ? 42.772 41.752  5.455  1.00 2.00  ? 220 ALA A N      1 
ATOM   3924 C CA     . ALA B 2 220 ? 42.358 42.898  4.649  1.00 2.01  ? 220 ALA A CA     1 
ATOM   3925 C C      . ALA B 2 220 ? 42.722 42.656  3.213  1.00 2.01  ? 220 ALA A C      1 
ATOM   3926 O O      . ALA B 2 220 ? 41.861 42.645  2.351  1.00 2.02  ? 220 ALA A O      1 
ATOM   3927 C CB     . ALA B 2 220 ? 43.007 44.129  5.110  1.00 2.01  ? 220 ALA A CB     1 
ATOM   3928 H H      . ALA B 2 220 ? 43.446 41.881  6.158  1.00 20.00 ? 220 ALA A H      1 
ATOM   3929 N N      . LEU B 2 221 ? 43.998 42.395  2.962  1.00 2.01  ? 221 LEU A N      1 
ATOM   3930 C CA     . LEU B 2 221 ? 44.448 42.133  1.607  1.00 2.01  ? 221 LEU A CA     1 
ATOM   3931 C C      . LEU B 2 221 ? 43.657 41.009  0.939  1.00 2.00  ? 221 LEU A C      1 
ATOM   3932 O O      . LEU B 2 221 ? 43.348 41.086  -0.250 1.00 2.51  ? 221 LEU A O      1 
ATOM   3933 C CB     . LEU B 2 221 ? 45.942 41.823  1.577  1.00 2.01  ? 221 LEU A CB     1 
ATOM   3934 C CG     . LEU B 2 221 ? 46.897 42.956  1.961  1.00 2.01  ? 221 LEU A CG     1 
ATOM   3935 C CD1    . LEU B 2 221 ? 48.312 42.465  1.862  1.00 2.01  ? 221 LEU A CD1    1 
ATOM   3936 C CD2    . LEU B 2 221 ? 46.700 44.170  1.054  1.00 2.00  ? 221 LEU A CD2    1 
ATOM   3937 H H      . LEU B 2 221 ? 44.635 42.368  3.701  1.00 20.00 ? 221 LEU A H      1 
ATOM   3938 N N      . GLU B 2 222 ? 43.288 39.983  1.684  1.00 2.01  ? 222 GLU A N      1 
ATOM   3939 C CA     . GLU B 2 222 ? 42.541 38.907  1.074  1.00 2.01  ? 222 GLU A CA     1 
ATOM   3940 C C      . GLU B 2 222 ? 41.067 39.195  0.991  1.00 2.01  ? 222 GLU A C      1 
ATOM   3941 O O      . GLU B 2 222 ? 40.324 38.433  0.400  1.00 2.00  ? 222 GLU A O      1 
ATOM   3942 C CB     . GLU B 2 222 ? 42.790 37.587  1.791  1.00 2.01  ? 222 GLU A CB     1 
ATOM   3943 C CG     . GLU B 2 222 ? 44.154 37.035  1.519  1.00 2.01  ? 222 GLU A CG     1 
ATOM   3944 C CD     . GLU B 2 222 ? 44.483 35.880  2.385  1.00 2.01  ? 222 GLU A CD     1 
ATOM   3945 O OE1    . GLU B 2 222 ? 43.587 35.258  2.976  1.00 2.02  ? 222 GLU A OE1    1 
ATOM   3946 O OE2    . GLU B 2 222 ? 45.674 35.593  2.493  1.00 2.01  ? 222 GLU A OE2    1 
ATOM   3947 H H      . GLU B 2 222 ? 43.498 39.945  2.635  1.00 20.00 ? 222 GLU A H      1 
ATOM   3948 N N      . GLY B 2 223 ? 40.620 40.275  1.592  1.00 2.01  ? 223 GLY A N      1 
ATOM   3949 C CA     . GLY B 2 223 ? 39.212 40.583  1.522  1.00 2.01  ? 223 GLY A CA     1 
ATOM   3950 C C      . GLY B 2 223 ? 38.357 39.675  2.358  1.00 2.01  ? 223 GLY A C      1 
ATOM   3951 O O      . GLY B 2 223 ? 37.237 39.366  1.965  1.00 2.00  ? 223 GLY A O      1 
ATOM   3952 H H      . GLY B 2 223 ? 41.219 40.843  2.096  1.00 20.00 ? 223 GLY A H      1 
ATOM   3953 N N      . ILE B 2 224 ? 38.882 39.245  3.502  1.00 2.01  ? 224 ILE A N      1 
ATOM   3954 C CA     . ILE B 2 224 ? 38.175 38.366  4.407  1.00 2.01  ? 224 ILE A CA     1 
ATOM   3955 C C      . ILE B 2 224 ? 37.080 39.179  5.020  1.00 2.01  ? 224 ILE A C      1 
ATOM   3956 O O      . ILE B 2 224 ? 37.324 40.291  5.440  1.00 2.01  ? 224 ILE A O      1 
ATOM   3957 C CB     . ILE B 2 224 ? 39.088 37.876  5.508  1.00 2.00  ? 224 ILE A CB     1 
ATOM   3958 C CG1    . ILE B 2 224 ? 40.161 36.942  4.941  1.00 2.01  ? 224 ILE A CG1    1 
ATOM   3959 C CG2    . ILE B 2 224 ? 38.238 37.245  6.609  1.00 2.01  ? 224 ILE A CG2    1 
ATOM   3960 C CD1    . ILE B 2 224 ? 39.621 35.705  4.353  1.00 2.01  ? 224 ILE A CD1    1 
ATOM   3961 H H      . ILE B 2 224 ? 39.789 39.524  3.734  1.00 20.00 ? 224 ILE A H      1 
ATOM   3962 N N      . THR B 2 225 ? 35.868 38.645  5.080  1.00 2.45  ? 225 THR A N      1 
ATOM   3963 C CA     . THR B 2 225 ? 34.762 39.401  5.662  1.00 2.01  ? 225 THR A CA     1 
ATOM   3964 C C      . THR B 2 225 ? 34.552 39.151  7.145  1.00 2.00  ? 225 THR A C      1 
ATOM   3965 O O      . THR B 2 225 ? 33.988 39.989  7.836  1.00 2.00  ? 225 THR A O      1 
ATOM   3966 C CB     . THR B 2 225 ? 33.462 39.131  4.976  1.00 2.01  ? 225 THR A CB     1 
ATOM   3967 O OG1    . THR B 2 225 ? 33.115 37.762  5.185  1.00 2.44  ? 225 THR A OG1    1 
ATOM   3968 C CG2    . THR B 2 225 ? 33.566 39.400  3.521  1.00 2.01  ? 225 THR A CG2    1 
ATOM   3969 H H      . THR B 2 225 ? 35.723 37.754  4.775  1.00 20.00 ? 225 THR A H      1 
ATOM   3970 H HG1    . THR B 2 225 ? 32.280 37.567  4.689  1.00 20.00 ? 225 THR A HG1    1 
ATOM   3971 N N      . HIS B 2 226 ? 34.887 37.963  7.623  1.00 2.00  ? 226 HIS A N      1 
ATOM   3972 C CA     . HIS B 2 226 ? 34.745 37.677  9.038  1.00 2.01  ? 226 HIS A CA     1 
ATOM   3973 C C      . HIS B 2 226 ? 35.931 36.855  9.501  1.00 2.00  ? 226 HIS A C      1 
ATOM   3974 O O      . HIS B 2 226 ? 36.147 35.756  9.001  1.00 2.00  ? 226 HIS A O      1 
ATOM   3975 C CB     . HIS B 2 226 ? 33.452 36.922  9.301  1.00 2.01  ? 226 HIS A CB     1 
ATOM   3976 C CG     . HIS B 2 226 ? 32.230 37.655  8.850  1.00 2.01  ? 226 HIS A CG     1 
ATOM   3977 N ND1    . HIS B 2 226 ? 31.904 37.810  7.515  1.00 2.00  ? 226 HIS A ND1    1 
ATOM   3978 C CD2    . HIS B 2 226 ? 31.229 38.243  9.540  1.00 2.00  ? 226 HIS A CD2    1 
ATOM   3979 C CE1    . HIS B 2 226 ? 30.755 38.450  7.407  1.00 2.01  ? 226 HIS A CE1    1 
ATOM   3980 N NE2    . HIS B 2 226 ? 30.327 38.722  8.626  1.00 2.00  ? 226 HIS A NE2    1 
ATOM   3981 H H      . HIS B 2 226 ? 35.256 37.278  7.034  1.00 20.00 ? 226 HIS A H      1 
ATOM   3982 H HD1    . HIS B 2 226 ? 32.445 37.511  6.774  1.00 20.00 ? 226 HIS A HD1    1 
ATOM   3983 H HE2    . HIS B 2 226 ? 29.482 39.194  8.836  1.00 20.00 ? 226 HIS A HE2    1 
ATOM   3984 N N      . SER B 2 227 ? 36.772 37.425  10.355 1.00 2.01  ? 227 SER A N      1 
ATOM   3985 C CA     . SER B 2 227 ? 37.900 36.700  10.885 1.00 2.01  ? 227 SER A CA     1 
ATOM   3986 C C      . SER B 2 227 ? 37.408 35.958  12.104 1.00 2.00  ? 227 SER A C      1 
ATOM   3987 O O      . SER B 2 227 ? 37.050 36.592  13.083 1.00 2.01  ? 227 SER A O      1 
ATOM   3988 C CB     . SER B 2 227 ? 39.000 37.655  11.293 1.00 2.00  ? 227 SER A CB     1 
ATOM   3989 O OG     . SER B 2 227 ? 39.944 37.811  10.251 1.00 2.01  ? 227 SER A OG     1 
ATOM   3990 H H      . SER B 2 227 ? 36.622 38.311  10.643 1.00 20.00 ? 227 SER A H      1 
ATOM   3991 H HG     . SER B 2 227 ? 40.612 38.421  10.583 1.00 20.00 ? 227 SER A HG     1 
ATOM   3992 N N      . LEU B 2 228 ? 37.382 34.628  12.054 1.00 2.01  ? 228 LEU A N      1 
ATOM   3993 C CA     . LEU B 2 228 ? 36.876 33.831  13.171 1.00 2.01  ? 228 LEU A CA     1 
ATOM   3994 C C      . LEU B 2 228 ? 38.028 33.119  13.848 1.00 2.00  ? 228 LEU A C      1 
ATOM   3995 O O      . LEU B 2 228 ? 38.787 32.412  13.213 1.00 2.00  ? 228 LEU A O      1 
ATOM   3996 C CB     . LEU B 2 228 ? 35.840 32.796  12.675 1.00 2.01  ? 228 LEU A CB     1 
ATOM   3997 C CG     . LEU B 2 228 ? 34.704 33.248  11.765 1.00 2.02  ? 228 LEU A CG     1 
ATOM   3998 C CD1    . LEU B 2 228 ? 34.095 32.083  11.147 1.00 2.01  ? 228 LEU A CD1    1 
ATOM   3999 C CD2    . LEU B 2 228 ? 33.676 34.045  12.497 1.00 2.01  ? 228 LEU A CD2    1 
ATOM   4000 H H      . LEU B 2 228 ? 37.652 34.138  11.233 1.00 20.00 ? 228 LEU A H      1 
ATOM   4001 N N      . CYS B 2 229 ? 38.158 33.281  15.151 1.00 2.00  ? 229 CYS A N      1 
ATOM   4002 C CA     . CYS B 2 229 ? 39.241 32.576  15.845 1.00 2.21  ? 229 CYS A CA     1 
ATOM   4003 C C      . CYS B 2 229 ? 38.813 32.360  17.290 1.00 2.00  ? 229 CYS A C      1 
ATOM   4004 O O      . CYS B 2 229 ? 37.700 32.737  17.660 1.00 2.60  ? 229 CYS A O      1 
ATOM   4005 C CB     . CYS B 2 229 ? 40.510 33.392  15.799 1.00 2.01  ? 229 CYS A CB     1 
ATOM   4006 S SG     . CYS B 2 229 ? 40.142 34.947  16.613 1.00 5.82  ? 229 CYS A SG     1 
ATOM   4007 H H      . CYS B 2 229 ? 37.580 33.937  15.630 1.00 20.00 ? 229 CYS A H      1 
ATOM   4008 N N      . THR B 2 230 ? 39.691 31.815  18.120 1.00 2.00  ? 230 THR A N      1 
ATOM   4009 C CA     . THR B 2 230 ? 39.315 31.524  19.484 1.00 2.01  ? 230 THR A CA     1 
ATOM   4010 C C      . THR B 2 230 ? 39.376 32.613  20.534 1.00 2.01  ? 230 THR A C      1 
ATOM   4011 O O      . THR B 2 230 ? 40.032 33.626  20.375 1.00 2.01  ? 230 THR A O      1 
ATOM   4012 C CB     . THR B 2 230 ? 39.984 30.263  19.967 1.00 2.01  ? 230 THR A CB     1 
ATOM   4013 O OG1    . THR B 2 230 ? 41.346 30.252  19.541 1.00 2.00  ? 230 THR A OG1    1 
ATOM   4014 C CG2    . THR B 2 230 ? 39.285 29.071  19.370 1.00 2.01  ? 230 THR A CG2    1 
ATOM   4015 H H      . THR B 2 230 ? 40.616 31.666  17.832 1.00 20.00 ? 230 THR A H      1 
ATOM   4016 H HG1    . THR B 2 230 ? 41.780 29.462  19.831 1.00 20.00 ? 230 THR A HG1    1 
ATOM   4017 N N      . LEU B 2 231 ? 38.689 32.366  21.633 1.00 2.01  ? 231 LEU A N      1 
ATOM   4018 C CA     . LEU B 2 231 ? 38.592 33.309  22.723 1.00 2.01  ? 231 LEU A CA     1 
ATOM   4019 C C      . LEU B 2 231 ? 39.828 34.055  23.241 1.00 2.01  ? 231 LEU A C      1 
ATOM   4020 O O      . LEU B 2 231 ? 39.711 35.225  23.561 1.00 2.00  ? 231 LEU A O      1 
ATOM   4021 C CB     . LEU B 2 231 ? 37.797 32.677  23.865 1.00 2.00  ? 231 LEU A CB     1 
ATOM   4022 C CG     . LEU B 2 231 ? 36.347 33.130  24.082 1.00 2.00  ? 231 LEU A CG     1 
ATOM   4023 C CD1    . LEU B 2 231 ? 35.674 33.403  22.781 1.00 2.00  ? 231 LEU A CD1    1 
ATOM   4024 C CD2    . LEU B 2 231 ? 35.578 32.084  24.827 1.00 2.01  ? 231 LEU A CD2    1 
ATOM   4025 H H      . LEU B 2 231 ? 38.237 31.498  21.718 1.00 20.00 ? 231 LEU A H      1 
ATOM   4026 N N      . GLU B 2 232 ? 41.011 33.450  23.278 1.00 2.00  ? 232 GLU A N      1 
ATOM   4027 C CA     . GLU B 2 232 ? 42.174 34.172  23.797 1.00 2.39  ? 232 GLU A CA     1 
ATOM   4028 C C      . GLU B 2 232 ? 42.473 35.438  23.043 1.00 2.49  ? 232 GLU A C      1 
ATOM   4029 O O      . GLU B 2 232 ? 43.267 36.240  23.514 1.00 2.01  ? 232 GLU A O      1 
ATOM   4030 C CB     . GLU B 2 232 ? 43.464 33.357  23.740 1.00 8.16  ? 232 GLU A CB     1 
ATOM   4031 C CG     . GLU B 2 232 ? 43.316 31.853  23.736 1.00 15.96 ? 232 GLU A CG     1 
ATOM   4032 C CD     . GLU B 2 232 ? 43.117 31.312  22.349 1.00 19.81 ? 232 GLU A CD     1 
ATOM   4033 O OE1    . GLU B 2 232 ? 41.971 31.344  21.886 1.00 18.69 ? 232 GLU A OE1    1 
ATOM   4034 O OE2    . GLU B 2 232 ? 44.082 30.871  21.706 1.00 21.55 ? 232 GLU A OE2    1 
ATOM   4035 H H      . GLU B 2 232 ? 41.064 32.540  23.046 1.00 20.00 ? 232 GLU A H      1 
ATOM   4036 N N      . PHE B 2 233 ? 41.900 35.582  21.845 1.00 3.03  ? 233 PHE A N      1 
ATOM   4037 C CA     . PHE B 2 233 ? 42.150 36.738  21.000 1.00 2.01  ? 233 PHE A CA     1 
ATOM   4038 C C      . PHE B 2 233 ? 41.180 37.912  21.161 1.00 3.65  ? 233 PHE A C      1 
ATOM   4039 O O      . PHE B 2 233 ? 41.297 38.908  20.438 1.00 4.57  ? 233 PHE A O      1 
ATOM   4040 C CB     . PHE B 2 233 ? 42.220 36.292  19.534 1.00 2.02  ? 233 PHE A CB     1 
ATOM   4041 C CG     . PHE B 2 233 ? 43.386 35.404  19.228 1.00 2.01  ? 233 PHE A CG     1 
ATOM   4042 C CD1    . PHE B 2 233 ? 44.681 35.899  19.231 1.00 2.09  ? 233 PHE A CD1    1 
ATOM   4043 C CD2    . PHE B 2 233 ? 43.214 34.067  18.986 1.00 2.01  ? 233 PHE A CD2    1 
ATOM   4044 C CE1    . PHE B 2 233 ? 45.780 35.080  19.004 1.00 2.01  ? 233 PHE A CE1    1 
ATOM   4045 C CE2    . PHE B 2 233 ? 44.316 33.248  18.760 1.00 2.01  ? 233 PHE A CE2    1 
ATOM   4046 C CZ     . PHE B 2 233 ? 45.590 33.765  18.771 1.00 2.02  ? 233 PHE A CZ     1 
ATOM   4047 H H      . PHE B 2 233 ? 41.261 34.894  21.517 1.00 20.00 ? 233 PHE A H      1 
ATOM   4048 N N      . GLN B 2 234 ? 40.254 37.839  22.120 1.00 2.00  ? 234 GLN A N      1 
ATOM   4049 C CA     . GLN B 2 234 ? 39.308 38.940  22.299 1.00 2.01  ? 234 GLN A CA     1 
ATOM   4050 C C      . GLN B 2 234 ? 40.036 40.236  22.621 1.00 2.00  ? 234 GLN A C      1 
ATOM   4051 O O      . GLN B 2 234 ? 39.681 41.269  22.069 1.00 3.00  ? 234 GLN A O      1 
ATOM   4052 C CB     . GLN B 2 234 ? 38.258 38.648  23.380 1.00 2.01  ? 234 GLN A CB     1 
ATOM   4053 C CG     . GLN B 2 234 ? 37.287 37.537  23.023 1.00 2.01  ? 234 GLN A CG     1 
ATOM   4054 C CD     . GLN B 2 234 ? 36.219 37.332  24.074 1.00 2.00  ? 234 GLN A CD     1 
ATOM   4055 O OE1    . GLN B 2 234 ? 35.044 37.646  23.839 1.00 2.56  ? 234 GLN A OE1    1 
ATOM   4056 N NE2    . GLN B 2 234 ? 36.608 36.824  25.237 1.00 2.01  ? 234 GLN A NE2    1 
ATOM   4057 H H      . GLN B 2 234 ? 40.218 37.046  22.720 1.00 20.00 ? 234 GLN A H      1 
ATOM   4058 H HE21   . GLN B 2 234 ? 35.904 36.714  25.925 1.00 20.00 ? 234 GLN A HE21   1 
ATOM   4059 H HE22   . GLN B 2 234 ? 37.530 36.620  25.374 1.00 20.00 ? 234 GLN A HE22   1 
ATOM   4060 N N      . ASP B 2 235 ? 41.064 40.184  23.482 1.00 2.00  ? 235 ASP A N      1 
ATOM   4061 C CA     . ASP B 2 235 ? 41.823 41.392  23.846 1.00 3.43  ? 235 ASP A CA     1 
ATOM   4062 C C      . ASP B 2 235 ? 42.559 41.864  22.626 1.00 3.35  ? 235 ASP A C      1 
ATOM   4063 O O      . ASP B 2 235 ? 42.539 43.048  22.297 1.00 4.17  ? 235 ASP A O      1 
ATOM   4064 C CB     . ASP B 2 235 ? 42.874 41.131  24.936 1.00 5.84  ? 235 ASP A CB     1 
ATOM   4065 C CG     . ASP B 2 235 ? 42.269 40.874  26.313 1.00 8.31  ? 235 ASP A CG     1 
ATOM   4066 O OD1    . ASP B 2 235 ? 41.864 41.848  26.990 1.00 10.90 ? 235 ASP A OD1    1 
ATOM   4067 O OD2    . ASP B 2 235 ? 42.195 39.694  26.728 1.00 8.38  ? 235 ASP A OD2    1 
ATOM   4068 H H      . ASP B 2 235 ? 41.304 39.334  23.893 1.00 20.00 ? 235 ASP A H      1 
ATOM   4069 N N      . ASN B 2 236 ? 43.174 40.902  21.945 1.00 2.00  ? 236 ASN A N      1 
ATOM   4070 C CA     . ASN B 2 236 ? 43.940 41.147  20.739 1.00 2.24  ? 236 ASN A CA     1 
ATOM   4071 C C      . ASN B 2 236 ? 43.133 41.886  19.693 1.00 2.00  ? 236 ASN A C      1 
ATOM   4072 O O      . ASN B 2 236 ? 43.683 42.706  18.938 1.00 3.26  ? 236 ASN A O      1 
ATOM   4073 C CB     . ASN B 2 236 ? 44.433 39.843  20.121 1.00 4.86  ? 236 ASN A CB     1 
ATOM   4074 C CG     . ASN B 2 236 ? 45.612 39.262  20.848 1.00 5.83  ? 236 ASN A CG     1 
ATOM   4075 O OD1    . ASN B 2 236 ? 45.566 39.021  22.050 1.00 6.36  ? 236 ASN A OD1    1 
ATOM   4076 N ND2    . ASN B 2 236 ? 46.669 38.998  20.116 1.00 8.13  ? 236 ASN A ND2    1 
ATOM   4077 H H      . ASN B 2 236 ? 43.132 39.969  22.282 1.00 20.00 ? 236 ASN A H      1 
ATOM   4078 H HD21   . ASN B 2 236 ? 47.427 38.607  20.602 1.00 20.00 ? 236 ASN A HD21   1 
ATOM   4079 H HD22   . ASN B 2 236 ? 46.646 39.148  19.186 1.00 20.00 ? 236 ASN A HD22   1 
ATOM   4080 N N      . ARG B 2 237 ? 41.836 41.624  19.635 1.00 2.00  ? 237 ARG A N      1 
ATOM   4081 C CA     . ARG B 2 237 ? 41.006 42.293  18.662 1.00 2.00  ? 237 ARG A CA     1 
ATOM   4082 C C      . ARG B 2 237 ? 41.258 43.788  18.641 1.00 2.55  ? 237 ARG A C      1 
ATOM   4083 O O      . ARG B 2 237 ? 41.208 44.399  17.592 1.00 3.95  ? 237 ARG A O      1 
ATOM   4084 C CB     . ARG B 2 237 ? 39.539 42.025  18.914 1.00 2.00  ? 237 ARG A CB     1 
ATOM   4085 C CG     . ARG B 2 237 ? 38.664 42.706  17.951 1.00 2.04  ? 237 ARG A CG     1 
ATOM   4086 C CD     . ARG B 2 237 ? 37.237 42.341  18.229 1.00 8.05  ? 237 ARG A CD     1 
ATOM   4087 N NE     . ARG B 2 237 ? 36.705 42.936  19.464 1.00 12.10 ? 237 ARG A NE     1 
ATOM   4088 C CZ     . ARG B 2 237 ? 36.340 42.237  20.534 1.00 12.94 ? 237 ARG A CZ     1 
ATOM   4089 N NH1    . ARG B 2 237 ? 36.477 40.917  20.556 1.00 15.12 ? 237 ARG A NH1    1 
ATOM   4090 N NH2    . ARG B 2 237 ? 35.862 42.858  21.593 1.00 16.19 ? 237 ARG A NH2    1 
ATOM   4091 H H      . ARG B 2 237 ? 41.435 40.966  20.230 1.00 20.00 ? 237 ARG A H      1 
ATOM   4092 H HE     . ARG B 2 237 ? 36.598 43.912  19.484 1.00 20.00 ? 237 ARG A HE     1 
ATOM   4093 H HH11   . ARG B 2 237 ? 36.896 40.447  19.785 1.00 20.00 ? 237 ARG A HH11   1 
ATOM   4094 H HH12   . ARG B 2 237 ? 36.238 40.415  21.383 1.00 20.00 ? 237 ARG A HH12   1 
ATOM   4095 H HH21   . ARG B 2 237 ? 35.778 43.860  21.576 1.00 20.00 ? 237 ARG A HH21   1 
ATOM   4096 H HH22   . ARG B 2 237 ? 35.605 42.343  22.397 1.00 20.00 ? 237 ARG A HH22   1 
ATOM   4097 N N      . ARG B 2 238 ? 41.570 44.379  19.779 1.00 2.00  ? 238 ARG A N      1 
ATOM   4098 C CA     . ARG B 2 238 ? 41.821 45.808  19.837 1.00 2.01  ? 238 ARG A CA     1 
ATOM   4099 C C      . ARG B 2 238 ? 43.016 46.216  18.982 1.00 2.01  ? 238 ARG A C      1 
ATOM   4100 O O      . ARG B 2 238 ? 42.994 47.276  18.369 1.00 2.01  ? 238 ARG A O      1 
ATOM   4101 C CB     . ARG B 2 238 ? 42.038 46.238  21.285 1.00 2.01  ? 238 ARG A CB     1 
ATOM   4102 C CG     . ARG B 2 238 ? 40.767 46.443  22.059 1.00 2.01  ? 238 ARG A CG     1 
ATOM   4103 C CD     . ARG B 2 238 ? 39.853 45.238  22.069 1.00 3.87  ? 238 ARG A CD     1 
ATOM   4104 N NE     . ARG B 2 238 ? 38.623 45.470  22.837 1.00 2.00  ? 238 ARG A NE     1 
ATOM   4105 C CZ     . ARG B 2 238 ? 38.004 44.537  23.564 1.00 2.00  ? 238 ARG A CZ     1 
ATOM   4106 N NH1    . ARG B 2 238 ? 38.468 43.293  23.605 1.00 2.00  ? 238 ARG A NH1    1 
ATOM   4107 N NH2    . ARG B 2 238 ? 36.901 44.828  24.233 1.00 4.69  ? 238 ARG A NH2    1 
ATOM   4108 H H      . ARG B 2 238 ? 41.622 43.843  20.599 1.00 20.00 ? 238 ARG A H      1 
ATOM   4109 H HE     . ARG B 2 238 ? 38.250 46.355  22.804 1.00 20.00 ? 238 ARG A HE     1 
ATOM   4110 H HH11   . ARG B 2 238 ? 39.288 43.019  23.087 1.00 20.00 ? 238 ARG A HH11   1 
ATOM   4111 H HH12   . ARG B 2 238 ? 37.970 42.578  24.117 1.00 20.00 ? 238 ARG A HH12   1 
ATOM   4112 H HH21   . ARG B 2 238 ? 36.520 45.740  24.149 1.00 20.00 ? 238 ARG A HH21   1 
ATOM   4113 H HH22   . ARG B 2 238 ? 36.415 44.103  24.714 1.00 20.00 ? 238 ARG A HH22   1 
ATOM   4114 N N      . LEU B 2 239 ? 44.051 45.378  18.941 1.00 2.01  ? 239 LEU A N      1 
ATOM   4115 C CA     . LEU B 2 239 ? 45.231 45.685  18.149 1.00 2.00  ? 239 LEU A CA     1 
ATOM   4116 C C      . LEU B 2 239 ? 44.894 45.492  16.668 1.00 2.00  ? 239 LEU A C      1 
ATOM   4117 O O      . LEU B 2 239 ? 45.282 46.282  15.800 1.00 2.01  ? 239 LEU A O      1 
ATOM   4118 C CB     . LEU B 2 239 ? 46.416 44.826  18.586 1.00 2.01  ? 239 LEU A CB     1 
ATOM   4119 C CG     . LEU B 2 239 ? 47.790 45.203  18.006 1.00 2.00  ? 239 LEU A CG     1 
ATOM   4120 C CD1    . LEU B 2 239 ? 48.076 46.706  17.973 1.00 2.02  ? 239 LEU A CD1    1 
ATOM   4121 C CD2    . LEU B 2 239 ? 48.835 44.454  18.800 1.00 2.01  ? 239 LEU A CD2    1 
ATOM   4122 H H      . LEU B 2 239 ? 44.031 44.559  19.462 1.00 20.00 ? 239 LEU A H      1 
ATOM   4123 N N      . TYR B 2 240 ? 44.067 44.493  16.405 1.00 2.01  ? 240 TYR A N      1 
ATOM   4124 C CA     . TYR B 2 240 ? 43.629 44.184  15.059 1.00 2.00  ? 240 TYR A CA     1 
ATOM   4125 C C      . TYR B 2 240 ? 43.080 45.493  14.521 1.00 2.01  ? 240 TYR A C      1 
ATOM   4126 O O      . TYR B 2 240 ? 43.651 46.094  13.628 1.00 2.01  ? 240 TYR A O      1 
ATOM   4127 C CB     . TYR B 2 240 ? 42.530 43.101  15.135 1.00 2.01  ? 240 TYR A CB     1 
ATOM   4128 C CG     . TYR B 2 240 ? 42.081 42.473  13.832 1.00 2.01  ? 240 TYR A CG     1 
ATOM   4129 C CD1    . TYR B 2 240 ? 41.172 43.100  13.020 1.00 2.00  ? 240 TYR A CD1    1 
ATOM   4130 C CD2    . TYR B 2 240 ? 42.496 41.209  13.467 1.00 2.00  ? 240 TYR A CD2    1 
ATOM   4131 C CE1    . TYR B 2 240 ? 40.672 42.479  11.881 1.00 2.00  ? 240 TYR A CE1    1 
ATOM   4132 C CE2    . TYR B 2 240 ? 42.002 40.584  12.331 1.00 2.01  ? 240 TYR A CE2    1 
ATOM   4133 C CZ     . TYR B 2 240 ? 41.092 41.218  11.550 1.00 2.01  ? 240 TYR A CZ     1 
ATOM   4134 O OH     . TYR B 2 240 ? 40.572 40.568  10.447 1.00 3.89  ? 240 TYR A OH     1 
ATOM   4135 H H      . TYR B 2 240 ? 43.776 43.932  17.149 1.00 20.00 ? 240 TYR A H      1 
ATOM   4136 H HH     . TYR B 2 240 ? 39.968 41.203  10.013 1.00 20.00 ? 240 TYR A HH     1 
ATOM   4137 N N      . ASP B 2 241 ? 42.033 45.984  15.149 1.00 2.01  ? 241 ASP A N      1 
ATOM   4138 C CA     . ASP B 2 241 ? 41.442 47.211  14.712 1.00 2.01  ? 241 ASP A CA     1 
ATOM   4139 C C      . ASP B 2 241 ? 42.402 48.397  14.702 1.00 2.00  ? 241 ASP A C      1 
ATOM   4140 O O      . ASP B 2 241 ? 42.400 49.194  13.764 1.00 2.00  ? 241 ASP A O      1 
ATOM   4141 C CB     . ASP B 2 241 ? 40.250 47.521  15.561 1.00 2.02  ? 241 ASP A CB     1 
ATOM   4142 C CG     . ASP B 2 241 ? 39.206 46.502  15.443 1.00 2.01  ? 241 ASP A CG     1 
ATOM   4143 O OD1    . ASP B 2 241 ? 39.223 45.799  14.428 1.00 2.01  ? 241 ASP A OD1    1 
ATOM   4144 O OD2    . ASP B 2 241 ? 38.375 46.401  16.366 1.00 2.01  ? 241 ASP A OD2    1 
ATOM   4145 H H      . ASP B 2 241 ? 41.644 45.499  15.903 1.00 20.00 ? 241 ASP A H      1 
ATOM   4146 N N      . TRP B 2 242 ? 43.245 48.525  15.714 1.00 2.01  ? 242 TRP A N      1 
ATOM   4147 C CA     . TRP B 2 242 ? 44.165 49.648  15.735 1.00 2.01  ? 242 TRP A CA     1 
ATOM   4148 C C      . TRP B 2 242 ? 45.088 49.667  14.517 1.00 3.28  ? 242 TRP A C      1 
ATOM   4149 O O      . TRP B 2 242 ? 45.311 50.713  13.912 1.00 2.00  ? 242 TRP A O      1 
ATOM   4150 C CB     . TRP B 2 242 ? 45.008 49.660  16.993 1.00 2.01  ? 242 TRP A CB     1 
ATOM   4151 C CG     . TRP B 2 242 ? 45.900 50.858  17.075 1.00 2.01  ? 242 TRP A CG     1 
ATOM   4152 C CD1    . TRP B 2 242 ? 45.565 52.070  17.552 1.00 2.01  ? 242 TRP A CD1    1 
ATOM   4153 C CD2    . TRP B 2 242 ? 47.262 50.960  16.633 1.00 2.01  ? 242 TRP A CD2    1 
ATOM   4154 N NE1    . TRP B 2 242 ? 46.616 52.929  17.447 1.00 2.01  ? 242 TRP A NE1    1 
ATOM   4155 C CE2    . TRP B 2 242 ? 47.672 52.276  16.884 1.00 2.01  ? 242 TRP A CE2    1 
ATOM   4156 C CE3    . TRP B 2 242 ? 48.172 50.066  16.047 1.00 2.01  ? 242 TRP A CE3    1 
ATOM   4157 C CZ2    . TRP B 2 242 ? 48.946 52.734  16.562 1.00 2.01  ? 242 TRP A CZ2    1 
ATOM   4158 C CZ3    . TRP B 2 242 ? 49.436 50.524  15.730 1.00 2.01  ? 242 TRP A CZ3    1 
ATOM   4159 C CH2    . TRP B 2 242 ? 49.813 51.851  15.993 1.00 2.01  ? 242 TRP A CH2    1 
ATOM   4160 H H      . TRP B 2 242 ? 43.233 47.869  16.433 1.00 20.00 ? 242 TRP A H      1 
ATOM   4161 H HE1    . TRP B 2 242 ? 46.612 53.863  17.734 1.00 20.00 ? 242 TRP A HE1    1 
ATOM   4162 N N      . VAL B 2 243 ? 45.658 48.527  14.161 1.00 2.00  ? 243 VAL A N      1 
ATOM   4163 C CA     . VAL B 2 243 ? 46.533 48.482  13.008 1.00 2.01  ? 243 VAL A CA     1 
ATOM   4164 C C      . VAL B 2 243 ? 45.711 48.909  11.780 1.00 2.01  ? 243 VAL A C      1 
ATOM   4165 O O      . VAL B 2 243 ? 45.985 49.946  11.194 1.00 2.01  ? 243 VAL A O      1 
ATOM   4166 C CB     . VAL B 2 243 ? 47.152 47.089  12.846 1.00 2.02  ? 243 VAL A CB     1 
ATOM   4167 C CG1    . VAL B 2 243 ? 48.033 47.041  11.684 1.00 2.01  ? 243 VAL A CG1    1 
ATOM   4168 C CG2    . VAL B 2 243 ? 47.939 46.732  14.081 1.00 2.01  ? 243 VAL A CG2    1 
ATOM   4169 H H      . VAL B 2 243 ? 45.432 47.698  14.652 1.00 20.00 ? 243 VAL A H      1 
ATOM   4170 N N      . LEU B 2 244 ? 44.615 48.210  11.492 1.00 2.01  ? 244 LEU A N      1 
ATOM   4171 C CA     . LEU B 2 244 ? 43.810 48.527  10.328 1.00 2.01  ? 244 LEU A CA     1 
ATOM   4172 C C      . LEU B 2 244 ? 43.333 49.951  10.266 1.00 2.01  ? 244 LEU A C      1 
ATOM   4173 O O      . LEU B 2 244 ? 43.081 50.467  9.192  1.00 2.00  ? 244 LEU A O      1 
ATOM   4174 C CB     . LEU B 2 244 ? 42.609 47.596  10.199 1.00 2.01  ? 244 LEU A CB     1 
ATOM   4175 C CG     . LEU B 2 244 ? 42.902 46.142  9.891  1.00 2.01  ? 244 LEU A CG     1 
ATOM   4176 C CD1    . LEU B 2 244 ? 41.603 45.495  9.637  1.00 2.00  ? 244 LEU A CD1    1 
ATOM   4177 C CD2    . LEU B 2 244 ? 43.760 46.011  8.691  1.00 2.01  ? 244 LEU A CD2    1 
ATOM   4178 H H      . LEU B 2 244 ? 44.321 47.471  12.087 1.00 20.00 ? 244 LEU A H      1 
ATOM   4179 N N      . ASP B 2 245 ? 43.185 50.595  11.409 1.00 2.00  ? 245 ASP A N      1 
ATOM   4180 C CA     . ASP B 2 245 ? 42.732 51.977  11.398 1.00 2.00  ? 245 ASP A CA     1 
ATOM   4181 C C      . ASP B 2 245 ? 43.795 53.004  11.089 1.00 2.00  ? 245 ASP A C      1 
ATOM   4182 O O      . ASP B 2 245 ? 43.454 54.122  10.746 1.00 2.00  ? 245 ASP A O      1 
ATOM   4183 C CB     . ASP B 2 245 ? 42.060 52.345  12.704 1.00 2.00  ? 245 ASP A CB     1 
ATOM   4184 C CG     . ASP B 2 245 ? 40.647 51.769  12.821 1.00 2.96  ? 245 ASP A CG     1 
ATOM   4185 O OD1    . ASP B 2 245 ? 40.037 51.411  11.775 1.00 5.98  ? 245 ASP A OD1    1 
ATOM   4186 O OD2    . ASP B 2 245 ? 40.146 51.669  13.973 1.00 5.50  ? 245 ASP A OD2    1 
ATOM   4187 H H      . ASP B 2 245 ? 43.401 50.163  12.256 1.00 20.00 ? 245 ASP A H      1 
ATOM   4188 N N      . ASN B 2 246 ? 45.068 52.623  11.137 1.00 4.39  ? 246 ASN A N      1 
ATOM   4189 C CA     . ASN B 2 246 ? 46.152 53.570  10.895 1.00 2.01  ? 246 ASN A CA     1 
ATOM   4190 C C      . ASN B 2 246 ? 47.074 53.337  9.696  1.00 2.01  ? 246 ASN A C      1 
ATOM   4191 O O      . ASN B 2 246 ? 48.227 53.765  9.689  1.00 2.02  ? 246 ASN A O      1 
ATOM   4192 C CB     . ASN B 2 246 ? 46.951 53.686  12.166 1.00 2.01  ? 246 ASN A CB     1 
ATOM   4193 C CG     . ASN B 2 246 ? 46.118 54.192  13.286 1.00 2.00  ? 246 ASN A CG     1 
ATOM   4194 O OD1    . ASN B 2 246 ? 45.792 55.364  13.306 1.00 7.98  ? 246 ASN A OD1    1 
ATOM   4195 N ND2    . ASN B 2 246 ? 45.693 53.324  14.187 1.00 2.00  ? 246 ASN A ND2    1 
ATOM   4196 H H      . ASN B 2 246 ? 45.285 51.686  11.327 1.00 20.00 ? 246 ASN A H      1 
ATOM   4197 H HD21   . ASN B 2 246 ? 45.134 53.680  14.902 1.00 20.00 ? 246 ASN A HD21   1 
ATOM   4198 H HD22   . ASN B 2 246 ? 45.916 52.398  14.076 1.00 20.00 ? 246 ASN A HD22   1 
ATOM   4199 N N      . ILE B 2 247 ? 46.575 52.648  8.684  1.00 2.01  ? 247 ILE A N      1 
ATOM   4200 C CA     . ILE B 2 247 ? 47.363 52.366  7.489  1.00 2.00  ? 247 ILE A CA     1 
ATOM   4201 C C      . ILE B 2 247 ? 46.396 52.472  6.313  1.00 2.00  ? 247 ILE A C      1 
ATOM   4202 O O      . ILE B 2 247 ? 45.190 52.290  6.464  1.00 2.00  ? 247 ILE A O      1 
ATOM   4203 C CB     . ILE B 2 247 ? 47.965 50.926  7.505  1.00 2.01  ? 247 ILE A CB     1 
ATOM   4204 C CG1    . ILE B 2 247 ? 46.852 49.889  7.516  1.00 2.00  ? 247 ILE A CG1    1 
ATOM   4205 C CG2    . ILE B 2 247 ? 48.837 50.697  8.709  1.00 2.01  ? 247 ILE A CG2    1 
ATOM   4206 C CD1    . ILE B 2 247 ? 47.339 48.484  7.580  1.00 2.00  ? 247 ILE A CD1    1 
ATOM   4207 H H      . ILE B 2 247 ? 45.650 52.306  8.738  1.00 20.00 ? 247 ILE A H      1 
ATOM   4208 N N      . THR B 2 248 ? 46.902 52.760  5.131  1.00 2.01  ? 248 THR A N      1 
ATOM   4209 C CA     . THR B 2 248 ? 46.019 52.864  3.995  1.00 2.00  ? 248 THR A CA     1 
ATOM   4210 C C      . THR B 2 248 ? 45.619 51.495  3.472  1.00 2.00  ? 248 THR A C      1 
ATOM   4211 O O      . THR B 2 248 ? 46.391 50.849  2.765  1.00 2.10  ? 248 THR A O      1 
ATOM   4212 C CB     . THR B 2 248 ? 46.687 53.607  2.903  1.00 2.01  ? 248 THR A CB     1 
ATOM   4213 O OG1    . THR B 2 248 ? 47.237 54.809  3.448  1.00 2.49  ? 248 THR A OG1    1 
ATOM   4214 C CG2    . THR B 2 248 ? 45.685 53.925  1.803  1.00 2.01  ? 248 THR A CG2    1 
ATOM   4215 H H      . THR B 2 248 ? 47.858 52.843  5.006  1.00 20.00 ? 248 THR A H      1 
ATOM   4216 H HG1    . THR B 2 248 ? 47.663 55.301  2.739  1.00 20.00 ? 248 THR A HG1    1 
ATOM   4217 N N      . ILE B 2 249 ? 44.426 51.042  3.835  1.00 2.00  ? 249 ILE A N      1 
ATOM   4218 C CA     . ILE B 2 249 ? 43.935 49.746  3.405  1.00 2.00  ? 249 ILE A CA     1 
ATOM   4219 C C      . ILE B 2 249 ? 42.483 50.069  3.139  1.00 2.01  ? 249 ILE A C      1 
ATOM   4220 O O      . ILE B 2 249 ? 41.903 50.842  3.862  1.00 2.00  ? 249 ILE A O      1 
ATOM   4221 C CB     . ILE B 2 249 ? 44.152 48.713  4.520  1.00 2.00  ? 249 ILE A CB     1 
ATOM   4222 C CG1    . ILE B 2 249 ? 43.828 47.313  4.036  1.00 2.00  ? 249 ILE A CG1    1 
ATOM   4223 C CG2    . ILE B 2 249 ? 43.384 49.073  5.757  1.00 2.01  ? 249 ILE A CG2    1 
ATOM   4224 C CD1    . ILE B 2 249 ? 45.069 46.565  3.652  1.00 3.51  ? 249 ILE A CD1    1 
ATOM   4225 H H      . ILE B 2 249 ? 43.841 51.613  4.387  1.00 20.00 ? 249 ILE A H      1 
ATOM   4226 N N      . PRO B 2 250 ? 41.872 49.516  2.103  1.00 2.01  ? 250 PRO A N      1 
ATOM   4227 C CA     . PRO B 2 250 ? 40.485 49.915  1.913  1.00 2.01  ? 250 PRO A CA     1 
ATOM   4228 C C      . PRO B 2 250 ? 39.363 49.118  2.534  1.00 2.00  ? 250 PRO A C      1 
ATOM   4229 O O      . PRO B 2 250 ? 38.204 49.435  2.291  1.00 2.01  ? 250 PRO A O      1 
ATOM   4230 C CB     . PRO B 2 250 ? 40.355 49.904  0.418  1.00 2.01  ? 250 PRO A CB     1 
ATOM   4231 C CG     . PRO B 2 250 ? 41.206 48.761  0.055  1.00 2.00  ? 250 PRO A CG     1 
ATOM   4232 C CD     . PRO B 2 250 ? 42.430 49.053  0.831  1.00 2.00  ? 250 PRO A CD     1 
ATOM   4233 N N      . VAL B 2 251 ? 39.667 48.059  3.280  1.00 2.00  ? 251 VAL A N      1 
ATOM   4234 C CA     . VAL B 2 251 ? 38.605 47.252  3.872  1.00 2.01  ? 251 VAL A CA     1 
ATOM   4235 C C      . VAL B 2 251 ? 39.003 46.989  5.286  1.00 2.01  ? 251 VAL A C      1 
ATOM   4236 O O      . VAL B 2 251 ? 40.169 47.096  5.590  1.00 2.00  ? 251 VAL A O      1 
ATOM   4237 C CB     . VAL B 2 251 ? 38.453 45.913  3.135  1.00 2.01  ? 251 VAL A CB     1 
ATOM   4238 C CG1    . VAL B 2 251 ? 37.988 46.173  1.711  1.00 2.00  ? 251 VAL A CG1    1 
ATOM   4239 C CG2    . VAL B 2 251 ? 39.767 45.159  3.130  1.00 2.00  ? 251 VAL A CG2    1 
ATOM   4240 H H      . VAL B 2 251 ? 40.608 47.789  3.381  1.00 20.00 ? 251 VAL A H      1 
ATOM   4241 N N      . HIS B 2 252 ? 38.056 46.649  6.145  1.00 2.00  ? 252 HIS A N      1 
ATOM   4242 C CA     . HIS B 2 252 ? 38.376 46.371  7.535  1.00 2.01  ? 252 HIS A CA     1 
ATOM   4243 C C      . HIS B 2 252 ? 37.630 45.149  8.052  1.00 2.01  ? 252 HIS A C      1 
ATOM   4244 O O      . HIS B 2 252 ? 36.558 45.265  8.631  1.00 2.01  ? 252 HIS A O      1 
ATOM   4245 C CB     . HIS B 2 252 ? 38.024 47.583  8.375  1.00 2.01  ? 252 HIS A CB     1 
ATOM   4246 C CG     . HIS B 2 252 ? 38.373 47.453  9.827  1.00 2.01  ? 252 HIS A CG     1 
ATOM   4247 N ND1    . HIS B 2 252 ? 38.849 48.504  10.565 1.00 2.01  ? 252 HIS A ND1    1 
ATOM   4248 C CD2    . HIS B 2 252 ? 38.264 46.408  10.682 1.00 2.01  ? 252 HIS A CD2    1 
ATOM   4249 C CE1    . HIS B 2 252 ? 39.024 48.124  11.818 1.00 2.01  ? 252 HIS A CE1    1 
ATOM   4250 N NE2    . HIS B 2 252 ? 38.676 46.857  11.912 1.00 2.01  ? 252 HIS A NE2    1 
ATOM   4251 H H      . HIS B 2 252 ? 37.127 46.577  5.829  1.00 20.00 ? 252 HIS A H      1 
ATOM   4252 H HD1    . HIS B 2 252 ? 39.039 49.416  10.220 1.00 20.00 ? 252 HIS A HD1    1 
ATOM   4253 H HE2    . HIS B 2 252 ? 38.704 46.310  12.689 1.00 20.00 ? 252 HIS A HE2    1 
ATOM   4254 N N      . PRO B 2 253 ? 38.200 43.952  7.857  1.00 3.07  ? 253 PRO A N      1 
ATOM   4255 C CA     . PRO B 2 253 ? 37.547 42.735  8.329  1.00 3.42  ? 253 PRO A CA     1 
ATOM   4256 C C      . PRO B 2 253 ? 37.230 42.805  9.818  1.00 3.59  ? 253 PRO A C      1 
ATOM   4257 O O      . PRO B 2 253 ? 37.962 43.446  10.595 1.00 2.01  ? 253 PRO A O      1 
ATOM   4258 C CB     . PRO B 2 253 ? 38.639 41.691  8.119  1.00 2.01  ? 253 PRO A CB     1 
ATOM   4259 C CG     . PRO B 2 253 ? 39.380 42.215  7.014  1.00 2.01  ? 253 PRO A CG     1 
ATOM   4260 C CD     . PRO B 2 253 ? 39.526 43.633  7.330  1.00 2.00  ? 253 PRO A CD     1 
ATOM   4261 N N      . ARG B 2 254 ? 36.167 42.118  10.229 1.00 2.67  ? 254 ARG A N      1 
ATOM   4262 C CA     . ARG B 2 254 ? 35.804 42.072  11.638 1.00 5.06  ? 254 ARG A CA     1 
ATOM   4263 C C      . ARG B 2 254 ? 36.098 40.687  12.194 1.00 3.85  ? 254 ARG A C      1 
ATOM   4264 O O      . ARG B 2 254 ? 35.879 39.686  11.505 1.00 2.80  ? 254 ARG A O      1 
ATOM   4265 C CB     . ARG B 2 254 ? 34.334 42.399  11.798 1.00 12.52 ? 254 ARG A CB     1 
ATOM   4266 C CG     . ARG B 2 254 ? 34.034 43.813  11.408 1.00 20.62 ? 254 ARG A CG     1 
ATOM   4267 C CD     . ARG B 2 254 ? 34.827 44.751  12.239 1.00 27.38 ? 254 ARG A CD     1 
ATOM   4268 N NE     . ARG B 2 254 ? 34.807 46.097  11.687 1.00 33.94 ? 254 ARG A NE     1 
ATOM   4269 C CZ     . ARG B 2 254 ? 35.397 47.151  12.256 1.00 37.87 ? 254 ARG A CZ     1 
ATOM   4270 N NH1    . ARG B 2 254 ? 36.053 47.027  13.412 1.00 38.38 ? 254 ARG A NH1    1 
ATOM   4271 N NH2    . ARG B 2 254 ? 35.327 48.336  11.666 1.00 38.64 ? 254 ARG A NH2    1 
ATOM   4272 H H      . ARG B 2 254 ? 35.626 41.637  9.568  1.00 20.00 ? 254 ARG A H      1 
ATOM   4273 H HE     . ARG B 2 254 ? 34.331 46.230  10.845 1.00 20.00 ? 254 ARG A HE     1 
ATOM   4274 H HH11   . ARG B 2 254 ? 36.098 46.137  13.875 1.00 20.00 ? 254 ARG A HH11   1 
ATOM   4275 H HH12   . ARG B 2 254 ? 36.479 47.825  13.833 1.00 20.00 ? 254 ARG A HH12   1 
ATOM   4276 H HH21   . ARG B 2 254 ? 34.832 48.415  10.796 1.00 20.00 ? 254 ARG A HH21   1 
ATOM   4277 H HH22   . ARG B 2 254 ? 35.758 49.125  12.078 1.00 20.00 ? 254 ARG A HH22   1 
ATOM   4278 N N      . GLN B 2 255 ? 36.658 40.641  13.408 1.00 2.19  ? 255 GLN A N      1 
ATOM   4279 C CA     . GLN B 2 255 ? 36.992 39.393  14.111 1.00 2.00  ? 255 GLN A CA     1 
ATOM   4280 C C      . GLN B 2 255 ? 35.894 39.007  15.090 1.00 2.00  ? 255 GLN A C      1 
ATOM   4281 O O      . GLN B 2 255 ? 35.308 39.868  15.745 1.00 2.00  ? 255 GLN A O      1 
ATOM   4282 C CB     . GLN B 2 255 ? 38.303 39.571  14.869 1.00 2.01  ? 255 GLN A CB     1 
ATOM   4283 C CG     . GLN B 2 255 ? 38.639 38.478  15.854 1.00 2.01  ? 255 GLN A CG     1 
ATOM   4284 C CD     . GLN B 2 255 ? 40.058 38.613  16.425 1.00 2.01  ? 255 GLN A CD     1 
ATOM   4285 O OE1    . GLN B 2 255 ? 41.058 38.495  15.707 1.00 2.01  ? 255 GLN A OE1    1 
ATOM   4286 N NE2    . GLN B 2 255 ? 40.142 38.852  17.727 1.00 2.01  ? 255 GLN A NE2    1 
ATOM   4287 H H      . GLN B 2 255 ? 36.830 41.488  13.858 1.00 20.00 ? 255 GLN A H      1 
ATOM   4288 H HE21   . GLN B 2 255 ? 41.051 38.942  18.105 1.00 20.00 ? 255 GLN A HE21   1 
ATOM   4289 H HE22   . GLN B 2 255 ? 39.353 38.926  18.274 1.00 20.00 ? 255 GLN A HE22   1 
ATOM   4290 N N      . TYR B 2 256 ? 35.570 37.721  15.128 1.00 2.01  ? 256 TYR A N      1 
ATOM   4291 C CA     . TYR B 2 256 ? 34.559 37.200  16.036 1.00 2.01  ? 256 TYR A CA     1 
ATOM   4292 C C      . TYR B 2 256 ? 35.202 35.984  16.649 1.00 2.01  ? 256 TYR A C      1 
ATOM   4293 O O      . TYR B 2 256 ? 35.904 35.240  15.977 1.00 3.75  ? 256 TYR A O      1 
ATOM   4294 C CB     . TYR B 2 256 ? 33.268 36.861  15.306 1.00 2.00  ? 256 TYR A CB     1 
ATOM   4295 C CG     . TYR B 2 256 ? 32.598 38.085  14.728 1.00 2.00  ? 256 TYR A CG     1 
ATOM   4296 C CD1    . TYR B 2 256 ? 31.866 38.932  15.535 1.00 2.01  ? 256 TYR A CD1    1 
ATOM   4297 C CD2    . TYR B 2 256 ? 32.698 38.398  13.364 1.00 2.00  ? 256 TYR A CD2    1 
ATOM   4298 C CE1    . TYR B 2 256 ? 31.246 40.062  15.010 1.00 2.00  ? 256 TYR A CE1    1 
ATOM   4299 C CE2    . TYR B 2 256 ? 32.075 39.530  12.825 1.00 2.01  ? 256 TYR A CE2    1 
ATOM   4300 C CZ     . TYR B 2 256 ? 31.354 40.353  13.661 1.00 2.01  ? 256 TYR A CZ     1 
ATOM   4301 O OH     . TYR B 2 256 ? 30.737 41.486  13.174 1.00 2.64  ? 256 TYR A OH     1 
ATOM   4302 H H      . TYR B 2 256 ? 36.015 37.100  14.531 1.00 20.00 ? 256 TYR A H      1 
ATOM   4303 H HH     . TYR B 2 256 ? 30.922 41.576  12.243 1.00 20.00 ? 256 TYR A HH     1 
ATOM   4304 N N      . GLU B 2 257 ? 34.980 35.790  17.941 1.00 2.01  ? 257 GLU A N      1 
ATOM   4305 C CA     . GLU B 2 257 ? 35.604 34.711  18.661 1.00 2.01  ? 257 GLU A CA     1 
ATOM   4306 C C      . GLU B 2 257 ? 34.634 33.722  19.255 1.00 2.01  ? 257 GLU A C      1 
ATOM   4307 O O      . GLU B 2 257 ? 33.579 34.110  19.757 1.00 2.01  ? 257 GLU A O      1 
ATOM   4308 C CB     . GLU B 2 257 ? 36.432 35.309  19.763 1.00 2.01  ? 257 GLU A CB     1 
ATOM   4309 C CG     . GLU B 2 257 ? 37.392 36.388  19.299 1.00 2.01  ? 257 GLU A CG     1 
ATOM   4310 C CD     . GLU B 2 257 ? 36.850 37.815  19.425 1.00 2.01  ? 257 GLU A CD     1 
ATOM   4311 O OE1    . GLU B 2 257 ? 35.629 38.025  19.520 1.00 2.01  ? 257 GLU A OE1    1 
ATOM   4312 O OE2    . GLU B 2 257 ? 37.663 38.750  19.413 1.00 2.01  ? 257 GLU A OE2    1 
ATOM   4313 H H      . GLU B 2 257 ? 34.366 36.391  18.434 1.00 20.00 ? 257 GLU A H      1 
ATOM   4314 N N      . PHE B 2 258 ? 34.995 32.448  19.190 1.00 2.01  ? 258 PHE A N      1 
ATOM   4315 C CA     . PHE B 2 258 ? 34.179 31.369  19.720 1.00 2.00  ? 258 PHE A CA     1 
ATOM   4316 C C      . PHE B 2 258 ? 35.115 30.575  20.620 1.00 2.00  ? 258 PHE A C      1 
ATOM   4317 O O      . PHE B 2 258 ? 36.327 30.698  20.476 1.00 2.00  ? 258 PHE A O      1 
ATOM   4318 C CB     . PHE B 2 258 ? 33.636 30.509  18.577 1.00 2.00  ? 258 PHE A CB     1 
ATOM   4319 C CG     . PHE B 2 258 ? 34.700 29.924  17.687 1.00 2.00  ? 258 PHE A CG     1 
ATOM   4320 C CD1    . PHE B 2 258 ? 35.261 30.676  16.671 1.00 2.00  ? 258 PHE A CD1    1 
ATOM   4321 C CD2    . PHE B 2 258 ? 35.163 28.637  17.881 1.00 2.01  ? 258 PHE A CD2    1 
ATOM   4322 C CE1    . PHE B 2 258 ? 36.256 30.175  15.875 1.00 2.01  ? 258 PHE A CE1    1 
ATOM   4323 C CE2    . PHE B 2 258 ? 36.154 28.134  17.085 1.00 2.01  ? 258 PHE A CE2    1 
ATOM   4324 C CZ     . PHE B 2 258 ? 36.702 28.908  16.083 1.00 2.00  ? 258 PHE A CZ     1 
ATOM   4325 H H      . PHE B 2 258 ? 35.833 32.221  18.755 1.00 20.00 ? 258 PHE A H      1 
ATOM   4326 N N      . SER B 2 259 ? 34.592 29.783  21.550 1.00 2.01  ? 259 SER A N      1 
ATOM   4327 C CA     . SER B 2 259 ? 35.417 29.016  22.464 1.00 2.00  ? 259 SER A CA     1 
ATOM   4328 C C      . SER B 2 259 ? 36.067 27.814  21.791 1.00 2.14  ? 259 SER A C      1 
ATOM   4329 O O      . SER B 2 259 ? 35.492 27.230  20.874 1.00 2.00  ? 259 SER A O      1 
ATOM   4330 C CB     . SER B 2 259 ? 34.570 28.522  23.629 1.00 3.13  ? 259 SER A CB     1 
ATOM   4331 O OG     . SER B 2 259 ? 33.493 27.732  23.160 1.00 2.00  ? 259 SER A OG     1 
ATOM   4332 H H      . SER B 2 259 ? 33.628 29.679  21.618 1.00 20.00 ? 259 SER A H      1 
ATOM   4333 H HG     . SER B 2 259 ? 32.959 27.453  23.900 1.00 20.00 ? 259 SER A HG     1 
ATOM   4334 N N      . ARG B 2 260 ? 37.252 27.442  22.268 1.00 3.44  ? 260 ARG A N      1 
ATOM   4335 C CA     . ARG B 2 260 ? 37.946 26.302  21.713 1.00 7.37  ? 260 ARG A CA     1 
ATOM   4336 C C      . ARG B 2 260 ? 37.483 24.994  22.324 1.00 7.61  ? 260 ARG A C      1 
ATOM   4337 O O      . ARG B 2 260 ? 36.841 24.964  23.389 1.00 7.42  ? 260 ARG A O      1 
ATOM   4338 C CB     . ARG B 2 260 ? 39.468 26.439  21.818 1.00 12.61 ? 260 ARG A CB     1 
ATOM   4339 C CG     . ARG B 2 260 ? 40.036 26.678  23.219 1.00 20.17 ? 260 ARG A CG     1 
ATOM   4340 C CD     . ARG B 2 260 ? 41.431 27.331  23.169 1.00 25.07 ? 260 ARG A CD     1 
ATOM   4341 N NE     . ARG B 2 260 ? 42.434 26.422  22.631 1.00 31.28 ? 260 ARG A NE     1 
ATOM   4342 C CZ     . ARG B 2 260 ? 43.397 26.788  21.789 1.00 34.52 ? 260 ARG A CZ     1 
ATOM   4343 N NH1    . ARG B 2 260 ? 43.488 28.054  21.371 1.00 36.16 ? 260 ARG A NH1    1 
ATOM   4344 N NH2    . ARG B 2 260 ? 44.265 25.880  21.352 1.00 37.15 ? 260 ARG A NH2    1 
ATOM   4345 H H      . ARG B 2 260 ? 37.617 27.886  23.083 1.00 20.00 ? 260 ARG A H      1 
ATOM   4346 H HE     . ARG B 2 260 ? 42.372 25.491  22.870 1.00 20.00 ? 260 ARG A HE     1 
ATOM   4347 H HH11   . ARG B 2 260 ? 42.833 28.747  21.649 1.00 20.00 ? 260 ARG A HH11   1 
ATOM   4348 H HH12   . ARG B 2 260 ? 44.234 28.317  20.729 1.00 20.00 ? 260 ARG A HH12   1 
ATOM   4349 H HH21   . ARG B 2 260 ? 44.182 24.934  21.652 1.00 20.00 ? 260 ARG A HH21   1 
ATOM   4350 H HH22   . ARG B 2 260 ? 45.004 26.149  20.728 1.00 20.00 ? 260 ARG A HH22   1 
ATOM   4351 N N      . LEU B 2 261 ? 37.767 23.922  21.593 1.00 5.52  ? 261 LEU A N      1 
ATOM   4352 C CA     . LEU B 2 261 ? 37.392 22.582  21.984 1.00 3.38  ? 261 LEU A CA     1 
ATOM   4353 C C      . LEU B 2 261 ? 38.382 21.972  22.938 1.00 2.00  ? 261 LEU A C      1 
ATOM   4354 O O      . LEU B 2 261 ? 39.597 22.007  22.682 1.00 2.00  ? 261 LEU A O      1 
ATOM   4355 C CB     . LEU B 2 261 ? 37.368 21.699  20.768 1.00 2.00  ? 261 LEU A CB     1 
ATOM   4356 C CG     . LEU B 2 261 ? 37.148 20.232  21.078 1.00 2.00  ? 261 LEU A CG     1 
ATOM   4357 C CD1    . LEU B 2 261 ? 35.679 20.086  21.435 1.00 2.34  ? 261 LEU A CD1    1 
ATOM   4358 C CD2    . LEU B 2 261 ? 37.499 19.416  19.844 1.00 2.00  ? 261 LEU A CD2    1 
ATOM   4359 H H      . LEU B 2 261 ? 38.263 24.044  20.773 1.00 20.00 ? 261 LEU A H      1 
ATOM   4360 N N      . ASN B 2 262 ? 37.855 21.397  24.011 1.00 2.00  ? 262 ASN A N      1 
ATOM   4361 C CA     . ASN B 2 262 ? 38.646 20.706  24.994 1.00 2.00  ? 262 ASN A CA     1 
ATOM   4362 C C      . ASN B 2 262 ? 38.041 19.324  25.018 1.00 2.00  ? 262 ASN A C      1 
ATOM   4363 O O      . ASN B 2 262 ? 36.813 19.158  24.965 1.00 2.00  ? 262 ASN A O      1 
ATOM   4364 C CB     . ASN B 2 262 ? 38.557 21.407  26.331 1.00 2.00  ? 262 ASN A CB     1 
ATOM   4365 C CG     . ASN B 2 262 ? 39.472 22.604  26.402 1.00 2.61  ? 262 ASN A CG     1 
ATOM   4366 O OD1    . ASN B 2 262 ? 40.660 22.504  26.078 1.00 2.86  ? 262 ASN A OD1    1 
ATOM   4367 N ND2    . ASN B 2 262 ? 38.937 23.758  26.794 1.00 3.57  ? 262 ASN A ND2    1 
ATOM   4368 H H      . ASN B 2 262 ? 36.876 21.425  24.139 1.00 20.00 ? 262 ASN A H      1 
ATOM   4369 H HD21   . ASN B 2 262 ? 39.496 24.536  26.821 1.00 20.00 ? 262 ASN A HD21   1 
ATOM   4370 H HD22   . ASN B 2 262 ? 37.964 23.764  27.016 1.00 20.00 ? 262 ASN A HD22   1 
ATOM   4371 N N      . LEU B 2 263 ? 38.897 18.324  24.941 1.00 2.01  ? 263 LEU A N      1 
ATOM   4372 C CA     . LEU B 2 263 ? 38.406 16.966  24.914 1.00 2.00  ? 263 LEU A CA     1 
ATOM   4373 C C      . LEU B 2 263 ? 38.931 16.323  26.145 1.00 2.50  ? 263 LEU A C      1 
ATOM   4374 O O      . LEU B 2 263 ? 40.092 16.551  26.514 1.00 5.99  ? 263 LEU A O      1 
ATOM   4375 C CB     . LEU B 2 263 ? 38.926 16.215  23.687 1.00 2.00  ? 263 LEU A CB     1 
ATOM   4376 C CG     . LEU B 2 263 ? 37.955 15.703  22.636 1.00 2.00  ? 263 LEU A CG     1 
ATOM   4377 C CD1    . LEU B 2 263 ? 38.632 14.624  21.840 1.00 2.00  ? 263 LEU A CD1    1 
ATOM   4378 C CD2    . LEU B 2 263 ? 36.737 15.144  23.340 1.00 2.00  ? 263 LEU A CD2    1 
ATOM   4379 H H      . LEU B 2 263 ? 39.853 18.499  24.907 1.00 20.00 ? 263 LEU A H      1 
ATOM   4380 N N      . GLU B 2 264 ? 38.080 15.516  26.764 1.00 2.47  ? 264 GLU A N      1 
ATOM   4381 C CA     . GLU B 2 264 ? 38.405 14.820  27.997 1.00 4.11  ? 264 GLU A CA     1 
ATOM   4382 C C      . GLU B 2 264 ? 39.504 13.806  27.720 1.00 4.13  ? 264 GLU A C      1 
ATOM   4383 O O      . GLU B 2 264 ? 39.572 13.245  26.639 1.00 5.87  ? 264 GLU A O      1 
ATOM   4384 C CB     . GLU B 2 264 ? 37.133 14.145  28.453 1.00 7.85  ? 264 GLU A CB     1 
ATOM   4385 C CG     . GLU B 2 264 ? 37.024 13.766  29.881 1.00 13.19 ? 264 GLU A CG     1 
ATOM   4386 C CD     . GLU B 2 264 ? 35.624 13.261  30.156 1.00 16.29 ? 264 GLU A CD     1 
ATOM   4387 O OE1    . GLU B 2 264 ? 35.249 12.164  29.620 1.00 16.24 ? 264 GLU A OE1    1 
ATOM   4388 O OE2    . GLU B 2 264 ? 34.899 14.002  30.865 1.00 17.66 ? 264 GLU A OE2    1 
ATOM   4389 H H      . GLU B 2 264 ? 37.179 15.417  26.404 1.00 20.00 ? 264 GLU A H      1 
ATOM   4390 N N      . TYR B 2 265 ? 40.381 13.599  28.684 1.00 3.22  ? 265 TYR A N      1 
ATOM   4391 C CA     . TYR B 2 265 ? 41.500 12.660  28.558 1.00 3.37  ? 265 TYR A CA     1 
ATOM   4392 C C      . TYR B 2 265 ? 42.566 12.939  27.512 1.00 2.52  ? 265 TYR A C      1 
ATOM   4393 O O      . TYR B 2 265 ? 43.411 12.087  27.282 1.00 3.77  ? 265 TYR A O      1 
ATOM   4394 C CB     . TYR B 2 265 ? 41.019 11.228  28.377 1.00 2.71  ? 265 TYR A CB     1 
ATOM   4395 C CG     . TYR B 2 265 ? 40.207 10.749  29.533 1.00 3.10  ? 265 TYR A CG     1 
ATOM   4396 C CD1    . TYR B 2 265 ? 40.809 10.391  30.739 1.00 5.27  ? 265 TYR A CD1    1 
ATOM   4397 C CD2    . TYR B 2 265 ? 38.829 10.720  29.457 1.00 5.88  ? 265 TYR A CD2    1 
ATOM   4398 C CE1    . TYR B 2 265 ? 40.054 10.030  31.832 1.00 4.84  ? 265 TYR A CE1    1 
ATOM   4399 C CE2    . TYR B 2 265 ? 38.075 10.350  30.541 1.00 5.54  ? 265 TYR A CE2    1 
ATOM   4400 C CZ     . TYR B 2 265 ? 38.692 10.014  31.714 1.00 8.59  ? 265 TYR A CZ     1 
ATOM   4401 O OH     . TYR B 2 265 ? 37.914 9.688   32.772 1.00 9.19  ? 265 TYR A OH     1 
ATOM   4402 H H      . TYR B 2 265 ? 40.316 14.149  29.480 1.00 20.00 ? 265 TYR A H      1 
ATOM   4403 H HH     . TYR B 2 265 ? 36.990 9.723   32.523 1.00 20.00 ? 265 TYR A HH     1 
ATOM   4404 N N      . THR B 2 266 ? 42.560 14.105  26.890 1.00 2.00  ? 266 THR A N      1 
ATOM   4405 C CA     . THR B 2 266 ? 43.579 14.379  25.887 1.00 2.00  ? 266 THR A CA     1 
ATOM   4406 C C      . THR B 2 266 ? 44.176 15.799  25.962 1.00 2.00  ? 266 THR A C      1 
ATOM   4407 O O      . THR B 2 266 ? 43.559 16.683  26.544 1.00 2.00  ? 266 THR A O      1 
ATOM   4408 C CB     . THR B 2 266 ? 43.012 14.094  24.479 1.00 2.00  ? 266 THR A CB     1 
ATOM   4409 O OG1    . THR B 2 266 ? 43.819 14.739  23.487 1.00 5.25  ? 266 THR A OG1    1 
ATOM   4410 C CG2    . THR B 2 266 ? 41.622 14.593  24.359 1.00 2.00  ? 266 THR A CG2    1 
ATOM   4411 H H      . THR B 2 266 ? 41.889 14.789  27.100 1.00 20.00 ? 266 THR A H      1 
ATOM   4412 H HG1    . THR B 2 266 ? 43.461 14.573  22.625 1.00 20.00 ? 266 THR A HG1    1 
ATOM   4413 N N      . VAL B 2 267 ? 45.399 16.000  25.470 1.00 2.01  ? 267 VAL A N      1 
ATOM   4414 C CA     . VAL B 2 267 ? 45.980 17.326  25.461 1.00 2.01  ? 267 VAL A CA     1 
ATOM   4415 C C      . VAL B 2 267 ? 45.961 17.830  24.007 1.00 4.09  ? 267 VAL A C      1 
ATOM   4416 O O      . VAL B 2 267 ? 46.198 17.072  23.085 1.00 5.18  ? 267 VAL A O      1 
ATOM   4417 C CB     . VAL B 2 267 ? 47.439 17.347  25.984 1.00 2.01  ? 267 VAL A CB     1 
ATOM   4418 C CG1    . VAL B 2 267 ? 47.487 17.045  27.456 1.00 2.00  ? 267 VAL A CG1    1 
ATOM   4419 C CG2    . VAL B 2 267 ? 48.307 16.347  25.220 1.00 2.01  ? 267 VAL A CG2    1 
ATOM   4420 H H      . VAL B 2 267 ? 45.888 15.249  25.068 1.00 20.00 ? 267 VAL A H      1 
ATOM   4421 N N      . MET B 2 268 ? 45.627 19.102  23.810 1.00 5.45  ? 268 MET A N      1 
ATOM   4422 C CA     . MET B 2 268 ? 45.583 19.713  22.477 1.00 4.63  ? 268 MET A CA     1 
ATOM   4423 C C      . MET B 2 268 ? 46.808 20.606  22.202 1.00 9.11  ? 268 MET A C      1 
ATOM   4424 O O      . MET B 2 268 ? 47.153 20.873  21.054 1.00 14.24 ? 268 MET A O      1 
ATOM   4425 C CB     . MET B 2 268 ? 44.348 20.605  22.367 1.00 2.00  ? 268 MET A CB     1 
ATOM   4426 C CG     . MET B 2 268 ? 43.012 19.879  22.414 1.00 5.14  ? 268 MET A CG     1 
ATOM   4427 S SD     . MET B 2 268 ? 42.636 18.979  20.883 1.00 9.13  ? 268 MET A SD     1 
ATOM   4428 C CE     . MET B 2 268 ? 41.054 18.386  21.316 1.00 5.72  ? 268 MET A CE     1 
ATOM   4429 H H      . MET B 2 268 ? 45.402 19.644  24.602 1.00 20.00 ? 268 MET A H      1 
ATOM   4430 N N      . SER B 2 269 ? 47.393 21.161  23.245 1.00 10.45 ? 269 SER A N      1 
ATOM   4431 C CA     . SER B 2 269 ? 48.535 22.037  23.077 1.00 11.88 ? 269 SER A CA     1 
ATOM   4432 C C      . SER B 2 269 ? 49.545 21.417  22.123 1.00 10.92 ? 269 SER A C      1 
ATOM   4433 O O      . SER B 2 269 ? 50.052 20.337  22.403 1.00 13.20 ? 269 SER A O      1 
ATOM   4434 C CB     . SER B 2 269 ? 49.169 22.251  24.449 1.00 16.39 ? 269 SER A CB     1 
ATOM   4435 O OG     . SER B 2 269 ? 50.579 22.332  24.368 1.00 22.46 ? 269 SER A OG     1 
ATOM   4436 H H      . SER B 2 269 ? 47.051 20.990  24.150 1.00 20.00 ? 269 SER A H      1 
ATOM   4437 H HG     . SER B 2 269 ? 50.963 22.492  25.244 1.00 20.00 ? 269 SER A HG     1 
ATOM   4438 N N      . LYS B 2 270 ? 49.839 22.057  21.002 1.00 9.19  ? 270 LYS A N      1 
ATOM   4439 C CA     . LYS B 2 270 ? 50.832 21.450  20.126 1.00 10.42 ? 270 LYS A CA     1 
ATOM   4440 C C      . LYS B 2 270 ? 52.216 21.327  20.786 1.00 12.11 ? 270 LYS A C      1 
ATOM   4441 O O      . LYS B 2 270 ? 53.000 20.453  20.437 1.00 12.45 ? 270 LYS A O      1 
ATOM   4442 C CB     . LYS B 2 270 ? 50.951 22.160  18.788 1.00 9.17  ? 270 LYS A CB     1 
ATOM   4443 C CG     . LYS B 2 270 ? 49.747 21.956  17.891 1.00 12.09 ? 270 LYS A CG     1 
ATOM   4444 C CD     . LYS B 2 270 ? 50.038 22.492  16.504 1.00 13.53 ? 270 LYS A CD     1 
ATOM   4445 C CE     . LYS B 2 270 ? 49.110 23.640  16.151 1.00 13.27 ? 270 LYS A CE     1 
ATOM   4446 N NZ     . LYS B 2 270 ? 49.737 24.503  15.096 1.00 17.22 ? 270 LYS A NZ     1 
ATOM   4447 H H      . LYS B 2 270 ? 49.434 22.919  20.794 1.00 20.00 ? 270 LYS A H      1 
ATOM   4448 H HZ1    . LYS B 2 270 ? 50.151 23.876  14.346 1.00 20.00 ? 270 LYS A HZ1    1 
ATOM   4449 H HZ2    . LYS B 2 270 ? 49.034 25.109  14.666 1.00 20.00 ? 270 LYS A HZ2    1 
ATOM   4450 H HZ3    . LYS B 2 270 ? 50.510 25.056  15.507 1.00 20.00 ? 270 LYS A HZ3    1 
ATOM   4451 N N      . ARG B 2 271 ? 52.503 22.171  21.769 1.00 13.44 ? 271 ARG A N      1 
ATOM   4452 C CA     . ARG B 2 271 ? 53.781 22.115  22.478 1.00 16.23 ? 271 ARG A CA     1 
ATOM   4453 C C      . ARG B 2 271 ? 53.859 20.747  23.133 1.00 12.16 ? 271 ARG A C      1 
ATOM   4454 O O      . ARG B 2 271 ? 54.869 20.049  23.050 1.00 9.49  ? 271 ARG A O      1 
ATOM   4455 C CB     . ARG B 2 271 ? 53.835 23.197  23.566 1.00 23.61 ? 271 ARG A CB     1 
ATOM   4456 C CG     . ARG B 2 271 ? 55.192 23.401  24.258 1.00 31.53 ? 271 ARG A CG     1 
ATOM   4457 C CD     . ARG B 2 271 ? 55.471 22.443  25.420 1.00 40.36 ? 271 ARG A CD     1 
ATOM   4458 N NE     . ARG B 2 271 ? 56.855 22.573  25.906 1.00 50.52 ? 271 ARG A NE     1 
ATOM   4459 C CZ     . ARG B 2 271 ? 57.232 23.301  26.961 1.00 54.05 ? 271 ARG A CZ     1 
ATOM   4460 N NH1    . ARG B 2 271 ? 56.335 23.954  27.690 1.00 56.28 ? 271 ARG A NH1    1 
ATOM   4461 N NH2    . ARG B 2 271 ? 58.515 23.359  27.309 1.00 56.24 ? 271 ARG A NH2    1 
ATOM   4462 H H      . ARG B 2 271 ? 51.854 22.845  22.006 1.00 20.00 ? 271 ARG A H      1 
ATOM   4463 H HE     . ARG B 2 271 ? 57.557 22.080  25.428 1.00 20.00 ? 271 ARG A HE     1 
ATOM   4464 H HH11   . ARG B 2 271 ? 55.369 23.912  27.440 1.00 20.00 ? 271 ARG A HH11   1 
ATOM   4465 H HH12   . ARG B 2 271 ? 56.627 24.496  28.477 1.00 20.00 ? 271 ARG A HH12   1 
ATOM   4466 H HH21   . ARG B 2 271 ? 59.201 22.835  26.809 1.00 20.00 ? 271 ARG A HH21   1 
ATOM   4467 H HH22   . ARG B 2 271 ? 58.790 23.887  28.120 1.00 20.00 ? 271 ARG A HH22   1 
ATOM   4468 N N      . LYS B 2 272 ? 52.764 20.374  23.782 1.00 9.65  ? 272 LYS A N      1 
ATOM   4469 C CA     . LYS B 2 272 ? 52.688 19.115  24.482 1.00 6.64  ? 272 LYS A CA     1 
ATOM   4470 C C      . LYS B 2 272 ? 52.704 17.933  23.536 1.00 4.94  ? 272 LYS A C      1 
ATOM   4471 O O      . LYS B 2 272 ? 53.505 17.002  23.729 1.00 5.46  ? 272 LYS A O      1 
ATOM   4472 C CB     . LYS B 2 272 ? 51.448 19.087  25.347 1.00 7.32  ? 272 LYS A CB     1 
ATOM   4473 C CG     . LYS B 2 272 ? 51.523 20.102  26.435 1.00 8.76  ? 272 LYS A CG     1 
ATOM   4474 C CD     . LYS B 2 272 ? 50.305 20.028  27.291 1.00 12.24 ? 272 LYS A CD     1 
ATOM   4475 C CE     . LYS B 2 272 ? 50.466 20.909  28.513 1.00 15.05 ? 272 LYS A CE     1 
ATOM   4476 N NZ     . LYS B 2 272 ? 49.296 21.804  28.721 1.00 13.60 ? 272 LYS A NZ     1 
ATOM   4477 H H      . LYS B 2 272 ? 51.985 20.966  23.748 1.00 20.00 ? 272 LYS A H      1 
ATOM   4478 H HZ1    . LYS B 2 272 ? 48.445 21.259  28.590 1.00 20.00 ? 272 LYS A HZ1    1 
ATOM   4479 H HZ2    . LYS B 2 272 ? 49.358 22.211  29.670 1.00 20.00 ? 272 LYS A HZ2    1 
ATOM   4480 H HZ3    . LYS B 2 272 ? 49.367 22.566  28.008 1.00 20.00 ? 272 LYS A HZ3    1 
ATOM   4481 N N      . LEU B 2 273 ? 51.860 17.981  22.497 1.00 3.28  ? 273 LEU A N      1 
ATOM   4482 C CA     . LEU B 2 273 ? 51.794 16.894  21.529 1.00 3.69  ? 273 LEU A CA     1 
ATOM   4483 C C      . LEU B 2 273 ? 53.189 16.725  20.958 1.00 7.30  ? 273 LEU A C      1 
ATOM   4484 O O      . LEU B 2 273 ? 53.693 15.620  20.751 1.00 6.20  ? 273 LEU A O      1 
ATOM   4485 C CB     . LEU B 2 273 ? 50.784 17.195  20.420 1.00 2.01  ? 273 LEU A CB     1 
ATOM   4486 C CG     . LEU B 2 273 ? 49.309 17.323  20.828 1.00 2.00  ? 273 LEU A CG     1 
ATOM   4487 C CD1    . LEU B 2 273 ? 48.440 17.694  19.609 1.00 2.00  ? 273 LEU A CD1    1 
ATOM   4488 C CD2    . LEU B 2 273 ? 48.809 15.997  21.458 1.00 2.00  ? 273 LEU A CD2    1 
ATOM   4489 H H      . LEU B 2 273 ? 51.213 18.716  22.441 1.00 20.00 ? 273 LEU A H      1 
ATOM   4490 N N      . ASN B 2 274 ? 53.881 17.835  20.831 1.00 9.67  ? 274 ASN A N      1 
ATOM   4491 C CA     . ASN B 2 274 ? 55.205 17.744  20.287 1.00 14.58 ? 274 ASN A CA     1 
ATOM   4492 C C      . ASN B 2 274 ? 56.123 17.010  21.237 1.00 14.79 ? 274 ASN A C      1 
ATOM   4493 O O      . ASN B 2 274 ? 57.055 16.339  20.808 1.00 16.20 ? 274 ASN A O      1 
ATOM   4494 C CB     . ASN B 2 274 ? 55.768 19.118  19.987 1.00 19.32 ? 274 ASN A CB     1 
ATOM   4495 C CG     . ASN B 2 274 ? 56.974 19.047  19.070 1.00 21.55 ? 274 ASN A CG     1 
ATOM   4496 O OD1    . ASN B 2 274 ? 56.829 19.047  17.858 1.00 24.51 ? 274 ASN A OD1    1 
ATOM   4497 N ND2    . ASN B 2 274 ? 58.156 18.937  19.641 1.00 20.37 ? 274 ASN A ND2    1 
ATOM   4498 H H      . ASN B 2 274 ? 53.504 18.687  21.110 1.00 20.00 ? 274 ASN A H      1 
ATOM   4499 H HD21   . ASN B 2 274 ? 58.895 18.897  19.013 1.00 20.00 ? 274 ASN A HD21   1 
ATOM   4500 H HD22   . ASN B 2 274 ? 58.201 18.914  20.597 1.00 20.00 ? 274 ASN A HD22   1 
ATOM   4501 N N      . LEU B 2 275 ? 55.874 17.146  22.531 1.00 15.54 ? 275 LEU A N      1 
ATOM   4502 C CA     . LEU B 2 275 ? 56.722 16.488  23.522 1.00 13.00 ? 275 LEU A CA     1 
ATOM   4503 C C      . LEU B 2 275 ? 56.527 14.979  23.448 1.00 12.15 ? 275 LEU A C      1 
ATOM   4504 O O      . LEU B 2 275 ? 57.515 14.232  23.389 1.00 12.88 ? 275 LEU A O      1 
ATOM   4505 C CB     . LEU B 2 275 ? 56.422 16.999  24.929 1.00 9.24  ? 275 LEU A CB     1 
ATOM   4506 C CG     . LEU B 2 275 ? 57.485 16.695  25.969 1.00 7.37  ? 275 LEU A CG     1 
ATOM   4507 C CD1    . LEU B 2 275 ? 58.773 17.354  25.566 1.00 10.18 ? 275 LEU A CD1    1 
ATOM   4508 C CD2    . LEU B 2 275 ? 57.003 17.199  27.310 1.00 6.36  ? 275 LEU A CD2    1 
ATOM   4509 H H      . LEU B 2 275 ? 55.131 17.699  22.830 1.00 20.00 ? 275 LEU A H      1 
ATOM   4510 N N      . LEU B 2 276 ? 55.274 14.533  23.415 1.00 8.90  ? 276 LEU A N      1 
ATOM   4511 C CA     . LEU B 2 276 ? 55.000 13.111  23.330 1.00 6.10  ? 276 LEU A CA     1 
ATOM   4512 C C      . LEU B 2 276 ? 55.763 12.521  22.153 1.00 6.55  ? 276 LEU A C      1 
ATOM   4513 O O      . LEU B 2 276 ? 56.379 11.459  22.287 1.00 7.56  ? 276 LEU A O      1 
ATOM   4514 C CB     . LEU B 2 276 ? 53.518 12.838  23.136 1.00 4.65  ? 276 LEU A CB     1 
ATOM   4515 C CG     . LEU B 2 276 ? 52.616 13.307  24.267 1.00 2.88  ? 276 LEU A CG     1 
ATOM   4516 C CD1    . LEU B 2 276 ? 51.187 13.211  23.809 1.00 2.58  ? 276 LEU A CD1    1 
ATOM   4517 C CD2    . LEU B 2 276 ? 52.839 12.472  25.506 1.00 2.46  ? 276 LEU A CD2    1 
ATOM   4518 H H      . LEU B 2 276 ? 54.542 15.171  23.420 1.00 20.00 ? 276 LEU A H      1 
ATOM   4519 N N      . VAL B 2 277 ? 55.779 13.235  21.025 1.00 4.97  ? 277 VAL A N      1 
ATOM   4520 C CA     . VAL B 2 277 ? 56.434 12.735  19.825 1.00 2.65  ? 277 VAL A CA     1 
ATOM   4521 C C      . VAL B 2 277 ? 57.954 12.749  19.879 1.00 4.74  ? 277 VAL A C      1 
ATOM   4522 O O      . VAL B 2 277 ? 58.628 11.762  19.550 1.00 4.56  ? 277 VAL A O      1 
ATOM   4523 C CB     . VAL B 2 277 ? 55.957 13.488  18.612 1.00 2.00  ? 277 VAL A CB     1 
ATOM   4524 C CG1    . VAL B 2 277 ? 56.558 12.878  17.375 1.00 2.39  ? 277 VAL A CG1    1 
ATOM   4525 C CG2    . VAL B 2 277 ? 54.464 13.432  18.525 1.00 2.00  ? 277 VAL A CG2    1 
ATOM   4526 H H      . VAL B 2 277 ? 55.315 14.084  20.981 1.00 20.00 ? 277 VAL A H      1 
ATOM   4527 N N      . THR B 2 278 ? 58.475 13.882  20.305 1.00 4.70  ? 278 THR A N      1 
ATOM   4528 C CA     . THR B 2 278 ? 59.898 14.091  20.441 1.00 6.78  ? 278 THR A CA     1 
ATOM   4529 C C      . THR B 2 278 ? 60.509 13.133  21.473 1.00 7.50  ? 278 THR A C      1 
ATOM   4530 O O      . THR B 2 278 ? 61.591 12.600  21.270 1.00 6.96  ? 278 THR A O      1 
ATOM   4531 C CB     . THR B 2 278 ? 60.137 15.553  20.882 1.00 7.09  ? 278 THR A CB     1 
ATOM   4532 O OG1    . THR B 2 278 ? 59.803 16.425  19.790 1.00 9.28  ? 278 THR A OG1    1 
ATOM   4533 C CG2    . THR B 2 278 ? 61.569 15.776  21.315 1.00 7.45  ? 278 THR A CG2    1 
ATOM   4534 H H      . THR B 2 278 ? 57.875 14.620  20.526 1.00 20.00 ? 278 THR A H      1 
ATOM   4535 H HG1    . THR B 2 278 ? 60.002 17.328  19.997 1.00 20.00 ? 278 THR A HG1    1 
ATOM   4536 N N      . ASP B 2 279 ? 59.823 12.933  22.588 1.00 11.03 ? 279 ASP A N      1 
ATOM   4537 C CA     . ASP B 2 279 ? 60.326 12.072  23.626 1.00 14.32 ? 279 ASP A CA     1 
ATOM   4538 C C      . ASP B 2 279 ? 59.968 10.638  23.373 1.00 15.61 ? 279 ASP A C      1 
ATOM   4539 O O      . ASP B 2 279 ? 60.031 9.806   24.276 1.00 15.49 ? 279 ASP A O      1 
ATOM   4540 C CB     . ASP B 2 279 ? 59.788 12.520  24.984 1.00 19.79 ? 279 ASP A CB     1 
ATOM   4541 C CG     . ASP B 2 279 ? 60.753 13.438  25.715 1.00 23.74 ? 279 ASP A CG     1 
ATOM   4542 O OD1    . ASP B 2 279 ? 61.656 14.006  25.041 1.00 25.60 ? 279 ASP A OD1    1 
ATOM   4543 O OD2    . ASP B 2 279 ? 60.624 13.564  26.963 1.00 24.38 ? 279 ASP A OD2    1 
ATOM   4544 H H      . ASP B 2 279 ? 59.004 13.414  22.732 1.00 20.00 ? 279 ASP A H      1 
ATOM   4545 N N      . LYS B 2 280 ? 59.542 10.370  22.146 1.00 16.83 ? 280 LYS A N      1 
ATOM   4546 C CA     . LYS B 2 280 ? 59.160 9.037   21.711 1.00 17.09 ? 280 LYS A CA     1 
ATOM   4547 C C      . LYS B 2 280 ? 58.109 8.327   22.571 1.00 12.18 ? 280 LYS A C      1 
ATOM   4548 O O      . LYS B 2 280 ? 58.115 7.100   22.622 1.00 12.01 ? 280 LYS A O      1 
ATOM   4549 C CB     . LYS B 2 280 ? 60.381 8.109   21.619 1.00 25.11 ? 280 LYS A CB     1 
ATOM   4550 C CG     . LYS B 2 280 ? 61.703 8.723   21.155 1.00 34.65 ? 280 LYS A CG     1 
ATOM   4551 C CD     . LYS B 2 280 ? 61.606 9.383   19.787 1.00 41.94 ? 280 LYS A CD     1 
ATOM   4552 C CE     . LYS B 2 280 ? 61.141 8.436   18.696 1.00 45.15 ? 280 LYS A CE     1 
ATOM   4553 N NZ     . LYS B 2 280 ? 60.570 9.200   17.538 1.00 46.67 ? 280 LYS A NZ     1 
ATOM   4554 H H      . LYS B 2 280 ? 59.449 11.100  21.494 1.00 20.00 ? 280 LYS A H      1 
ATOM   4555 H HZ1    . LYS B 2 280 ? 61.222 9.964   17.291 1.00 20.00 ? 280 LYS A HZ1    1 
ATOM   4556 H HZ2    . LYS B 2 280 ? 60.464 8.554   16.723 1.00 20.00 ? 280 LYS A HZ2    1 
ATOM   4557 H HZ3    . LYS B 2 280 ? 59.644 9.584   17.796 1.00 20.00 ? 280 LYS A HZ3    1 
ATOM   4558 N N      . HIS B 2 281 ? 57.241 9.046   23.285 1.00 6.62  ? 281 HIS A N      1 
ATOM   4559 C CA     . HIS B 2 281 ? 56.229 8.340   24.066 1.00 3.66  ? 281 HIS A CA     1 
ATOM   4560 C C      . HIS B 2 281 ? 55.116 7.796   23.187 1.00 3.56  ? 281 HIS A C      1 
ATOM   4561 O O      . HIS B 2 281 ? 54.313 7.007   23.655 1.00 3.58  ? 281 HIS A O      1 
ATOM   4562 C CB     . HIS B 2 281 ? 55.694 9.148   25.247 1.00 2.78  ? 281 HIS A CB     1 
ATOM   4563 C CG     . HIS B 2 281 ? 56.737 9.411   26.286 1.00 2.01  ? 281 HIS A CG     1 
ATOM   4564 N ND1    . HIS B 2 281 ? 57.046 10.676  26.732 1.00 2.01  ? 281 HIS A ND1    1 
ATOM   4565 C CD2    . HIS B 2 281 ? 57.657 8.589   26.842 1.00 2.00  ? 281 HIS A CD2    1 
ATOM   4566 C CE1    . HIS B 2 281 ? 58.114 10.631  27.501 1.00 2.00  ? 281 HIS A CE1    1 
ATOM   4567 N NE2    . HIS B 2 281 ? 58.512 9.372   27.584 1.00 6.74  ? 281 HIS A NE2    1 
ATOM   4568 H H      . HIS B 2 281 ? 57.256 10.025  23.250 1.00 20.00 ? 281 HIS A H      1 
ATOM   4569 H HD1    . HIS B 2 281 ? 56.597 11.491  26.493 1.00 20.00 ? 281 HIS A HD1    1 
ATOM   4570 H HE2    . HIS B 2 281 ? 59.318 9.023   28.100 1.00 20.00 ? 281 HIS A HE2    1 
ATOM   4571 N N      . VAL B 2 282 ? 55.057 8.229   21.928 1.00 2.00  ? 282 VAL A N      1 
ATOM   4572 C CA     . VAL B 2 282 ? 54.084 7.712   20.964 1.00 3.30  ? 282 VAL A CA     1 
ATOM   4573 C C      . VAL B 2 282 ? 54.890 7.521   19.669 1.00 5.05  ? 282 VAL A C      1 
ATOM   4574 O O      . VAL B 2 282 ? 56.006 8.029   19.552 1.00 4.55  ? 282 VAL A O      1 
ATOM   4575 C CB     . VAL B 2 282 ? 52.878 8.644   20.722 1.00 2.01  ? 282 VAL A CB     1 
ATOM   4576 C CG1    . VAL B 2 282 ? 51.963 8.653   21.920 1.00 2.01  ? 282 VAL A CG1    1 
ATOM   4577 C CG2    . VAL B 2 282 ? 53.342 10.032  20.420 1.00 2.01  ? 282 VAL A CG2    1 
ATOM   4578 H H      . VAL B 2 282 ? 55.745 8.862   21.608 1.00 20.00 ? 282 VAL A H      1 
ATOM   4579 N N      . GLU B 2 283 ? 54.338 6.788   18.705 1.00 8.12  ? 283 GLU A N      1 
ATOM   4580 C CA     . GLU B 2 283 ? 55.029 6.503   17.458 1.00 10.70 ? 283 GLU A CA     1 
ATOM   4581 C C      . GLU B 2 283 ? 55.366 7.705   16.630 1.00 8.91  ? 283 GLU A C      1 
ATOM   4582 O O      . GLU B 2 283 ? 56.409 7.744   15.978 1.00 8.51  ? 283 GLU A O      1 
ATOM   4583 C CB     . GLU B 2 283 ? 54.218 5.532   16.615 1.00 18.14 ? 283 GLU A CB     1 
ATOM   4584 C CG     . GLU B 2 283 ? 54.258 4.113   17.146 1.00 24.59 ? 283 GLU A CG     1 
ATOM   4585 C CD     . GLU B 2 283 ? 53.334 3.187   16.388 1.00 32.41 ? 283 GLU A CD     1 
ATOM   4586 O OE1    . GLU B 2 283 ? 53.309 3.296   15.130 1.00 33.85 ? 283 GLU A OE1    1 
ATOM   4587 O OE2    . GLU B 2 283 ? 52.641 2.368   17.063 1.00 32.83 ? 283 GLU A OE2    1 
ATOM   4588 H H      . GLU B 2 283 ? 53.451 6.433   18.849 1.00 20.00 ? 283 GLU A H      1 
ATOM   4589 N N      . GLY B 2 284 ? 54.454 8.671   16.621 1.00 6.88  ? 284 GLY A N      1 
ATOM   4590 C CA     . GLY B 2 284 ? 54.654 9.890   15.856 1.00 5.20  ? 284 GLY A CA     1 
ATOM   4591 C C      . GLY B 2 284 ? 53.332 10.602  15.822 1.00 6.10  ? 284 GLY A C      1 
ATOM   4592 O O      . GLY B 2 284 ? 52.360 10.056  16.331 1.00 6.94  ? 284 GLY A O      1 
ATOM   4593 H H      . GLY B 2 284 ? 53.627 8.566   17.120 1.00 20.00 ? 284 GLY A H      1 
ATOM   4594 N N      . TRP B 2 285 ? 53.266 11.765  15.178 1.00 2.97  ? 285 TRP A N      1 
ATOM   4595 C CA     . TRP B 2 285 ? 52.040 12.564  15.113 1.00 2.00  ? 285 TRP A CA     1 
ATOM   4596 C C      . TRP B 2 285 ? 50.773 11.843  14.732 1.00 2.00  ? 285 TRP A C      1 
ATOM   4597 O O      . TRP B 2 285 ? 49.698 12.256  15.136 1.00 2.00  ? 285 TRP A O      1 
ATOM   4598 C CB     . TRP B 2 285 ? 52.220 13.745  14.189 1.00 2.00  ? 285 TRP A CB     1 
ATOM   4599 C CG     . TRP B 2 285 ? 53.238 14.688  14.680 1.00 2.00  ? 285 TRP A CG     1 
ATOM   4600 C CD1    . TRP B 2 285 ? 54.572 14.702  14.357 1.00 2.00  ? 285 TRP A CD1    1 
ATOM   4601 C CD2    . TRP B 2 285 ? 53.012 15.826  15.506 1.00 2.01  ? 285 TRP A CD2    1 
ATOM   4602 N NE1    . TRP B 2 285 ? 55.181 15.793  14.929 1.00 2.00  ? 285 TRP A NE1    1 
ATOM   4603 C CE2    . TRP B 2 285 ? 54.249 16.505  15.638 1.00 2.00  ? 285 TRP A CE2    1 
ATOM   4604 C CE3    . TRP B 2 285 ? 51.880 16.361  16.138 1.00 2.00  ? 285 TRP A CE3    1 
ATOM   4605 C CZ2    . TRP B 2 285 ? 54.385 17.682  16.374 1.00 2.01  ? 285 TRP A CZ2    1 
ATOM   4606 C CZ3    . TRP B 2 285 ? 52.016 17.541  16.871 1.00 2.01  ? 285 TRP A CZ3    1 
ATOM   4607 C CH2    . TRP B 2 285 ? 53.266 18.185  16.980 1.00 2.01  ? 285 TRP A CH2    1 
ATOM   4608 H H      . TRP B 2 285 ? 54.057 12.065  14.701 1.00 20.00 ? 285 TRP A H      1 
ATOM   4609 H HE1    . TRP B 2 285 ? 56.136 16.027  14.834 1.00 20.00 ? 285 TRP A HE1    1 
ATOM   4610 N N      . ASP B 2 286 ? 50.890 10.787  13.938 1.00 2.00  ? 286 ASP A N      1 
ATOM   4611 C CA     . ASP B 2 286 ? 49.731 10.028  13.499 1.00 2.00  ? 286 ASP A CA     1 
ATOM   4612 C C      . ASP B 2 286 ? 49.562 8.718   14.257 1.00 2.00  ? 286 ASP A C      1 
ATOM   4613 O O      . ASP B 2 286 ? 49.107 7.732   13.691 1.00 2.00  ? 286 ASP A O      1 
ATOM   4614 C CB     . ASP B 2 286 ? 49.809 9.757   12.002 1.00 2.01  ? 286 ASP A CB     1 
ATOM   4615 C CG     . ASP B 2 286 ? 50.844 8.713   11.635 1.00 4.46  ? 286 ASP A CG     1 
ATOM   4616 O OD1    . ASP B 2 286 ? 51.819 8.470   12.368 1.00 4.32  ? 286 ASP A OD1    1 
ATOM   4617 O OD2    . ASP B 2 286 ? 50.651 8.105   10.578 1.00 9.38  ? 286 ASP A OD2    1 
ATOM   4618 H H      . ASP B 2 286 ? 51.773 10.506  13.648 1.00 20.00 ? 286 ASP A H      1 
ATOM   4619 N N      . ASP B 2 287 ? 50.087 8.654   15.471 1.00 2.47  ? 287 ASP A N      1 
ATOM   4620 C CA     . ASP B 2 287 ? 49.942 7.466   16.288 1.00 5.27  ? 287 ASP A CA     1 
ATOM   4621 C C      . ASP B 2 287 ? 48.425 7.391   16.565 1.00 6.37  ? 287 ASP A C      1 
ATOM   4622 O O      . ASP B 2 287 ? 47.796 8.425   16.805 1.00 6.90  ? 287 ASP A O      1 
ATOM   4623 C CB     . ASP B 2 287 ? 50.728 7.650   17.578 1.00 6.60  ? 287 ASP A CB     1 
ATOM   4624 C CG     . ASP B 2 287 ? 50.581 6.482   18.508 1.00 10.03 ? 287 ASP A CG     1 
ATOM   4625 O OD1    . ASP B 2 287 ? 49.500 6.346   19.129 1.00 11.15 ? 287 ASP A OD1    1 
ATOM   4626 O OD2    . ASP B 2 287 ? 51.551 5.694   18.592 1.00 11.00 ? 287 ASP A OD2    1 
ATOM   4627 H H      . ASP B 2 287 ? 50.593 9.409   15.810 1.00 20.00 ? 287 ASP A H      1 
ATOM   4628 N N      . PRO B 2 288 ? 47.840 6.184   16.610 1.00 5.35  ? 288 PRO A N      1 
ATOM   4629 C CA     . PRO B 2 288 ? 46.402 6.165   16.860 1.00 4.19  ? 288 PRO A CA     1 
ATOM   4630 C C      . PRO B 2 288 ? 45.883 6.716   18.171 1.00 5.78  ? 288 PRO A C      1 
ATOM   4631 O O      . PRO B 2 288 ? 44.685 6.909   18.305 1.00 9.29  ? 288 PRO A O      1 
ATOM   4632 C CB     . PRO B 2 288 ? 46.039 4.714   16.693 1.00 4.20  ? 288 PRO A CB     1 
ATOM   4633 C CG     . PRO B 2 288 ? 46.916 4.342   15.579 1.00 3.28  ? 288 PRO A CG     1 
ATOM   4634 C CD     . PRO B 2 288 ? 48.254 4.919   15.988 1.00 2.87  ? 288 PRO A CD     1 
ATOM   4635 N N      . ARG B 2 289 ? 46.722 6.911   19.182 1.00 3.61  ? 289 ARG A N      1 
ATOM   4636 C CA     . ARG B 2 289 ? 46.225 7.490   20.451 1.00 4.17  ? 289 ARG A CA     1 
ATOM   4637 C C      . ARG B 2 289 ? 46.242 9.033   20.442 1.00 5.57  ? 289 ARG A C      1 
ATOM   4638 O O      . ARG B 2 289 ? 45.747 9.662   21.377 1.00 7.60  ? 289 ARG A O      1 
ATOM   4639 C CB     . ARG B 2 289 ? 47.056 7.023   21.656 1.00 4.57  ? 289 ARG A CB     1 
ATOM   4640 C CG     . ARG B 2 289 ? 46.979 5.542   21.944 1.00 7.68  ? 289 ARG A CG     1 
ATOM   4641 C CD     . ARG B 2 289 ? 48.223 4.831   21.437 1.00 6.38  ? 289 ARG A CD     1 
ATOM   4642 N NE     . ARG B 2 289 ? 49.257 4.724   22.444 1.00 3.89  ? 289 ARG A NE     1 
ATOM   4643 C CZ     . ARG B 2 289 ? 50.534 4.534   22.157 1.00 5.70  ? 289 ARG A CZ     1 
ATOM   4644 N NH1    . ARG B 2 289 ? 50.926 4.441   20.905 1.00 6.69  ? 289 ARG A NH1    1 
ATOM   4645 N NH2    . ARG B 2 289 ? 51.431 4.438   23.119 1.00 7.43  ? 289 ARG A NH2    1 
ATOM   4646 H H      . ARG B 2 289 ? 47.641 6.688   19.079 1.00 20.00 ? 289 ARG A H      1 
ATOM   4647 H HE     . ARG B 2 289 ? 49.013 4.824   23.393 1.00 20.00 ? 289 ARG A HE     1 
ATOM   4648 H HH11   . ARG B 2 289 ? 50.275 4.546   20.171 1.00 20.00 ? 289 ARG A HH11   1 
ATOM   4649 H HH12   . ARG B 2 289 ? 51.897 4.270   20.705 1.00 20.00 ? 289 ARG A HH12   1 
ATOM   4650 H HH21   . ARG B 2 289 ? 51.147 4.467   24.086 1.00 20.00 ? 289 ARG A HH21   1 
ATOM   4651 H HH22   . ARG B 2 289 ? 52.390 4.226   22.909 1.00 20.00 ? 289 ARG A HH22   1 
ATOM   4652 N N      . MET B 2 290 ? 46.881 9.635   19.434 1.00 4.05  ? 290 MET A N      1 
ATOM   4653 C CA     . MET B 2 290 ? 46.991 11.090  19.347 1.00 2.01  ? 290 MET A CA     1 
ATOM   4654 C C      . MET B 2 290 ? 45.673 11.684  18.969 1.00 2.01  ? 290 MET A C      1 
ATOM   4655 O O      . MET B 2 290 ? 44.900 11.020  18.297 1.00 2.00  ? 290 MET A O      1 
ATOM   4656 C CB     . MET B 2 290 ? 48.016 11.456  18.294 1.00 2.01  ? 290 MET A CB     1 
ATOM   4657 C CG     . MET B 2 290 ? 49.437 11.230  18.742 1.00 2.00  ? 290 MET A CG     1 
ATOM   4658 S SD     . MET B 2 290 ? 49.842 12.344  20.080 1.00 2.01  ? 290 MET A SD     1 
ATOM   4659 C CE     . MET B 2 290 ? 50.999 13.263  19.253 1.00 2.01  ? 290 MET A CE     1 
ATOM   4660 H H      . MET B 2 290 ? 47.270 9.088   18.728 1.00 20.00 ? 290 MET A H      1 
ATOM   4661 N N      . PRO B 2 291 ? 45.386 12.935  19.385 1.00 2.01  ? 291 PRO A N      1 
ATOM   4662 C CA     . PRO B 2 291 ? 44.095 13.540  19.022 1.00 2.01  ? 291 PRO A CA     1 
ATOM   4663 C C      . PRO B 2 291 ? 44.208 14.261  17.682 1.00 2.00  ? 291 PRO A C      1 
ATOM   4664 O O      . PRO B 2 291 ? 43.371 15.110  17.358 1.00 2.01  ? 291 PRO A O      1 
ATOM   4665 C CB     . PRO B 2 291 ? 43.852 14.551  20.136 1.00 2.01  ? 291 PRO A CB     1 
ATOM   4666 C CG     . PRO B 2 291 ? 45.244 15.087  20.369 1.00 2.01  ? 291 PRO A CG     1 
ATOM   4667 C CD     . PRO B 2 291 ? 46.114 13.808  20.333 1.00 2.00  ? 291 PRO A CD     1 
ATOM   4668 N N      . THR B 2 292 ? 45.280 13.979  16.944 1.00 2.00  ? 292 THR A N      1 
ATOM   4669 C CA     . THR B 2 292 ? 45.475 14.597  15.660 1.00 2.01  ? 292 THR A CA     1 
ATOM   4670 C C      . THR B 2 292 ? 44.514 13.979  14.616 1.00 3.17  ? 292 THR A C      1 
ATOM   4671 O O      . THR B 2 292 ? 44.020 12.851  14.779 1.00 2.01  ? 292 THR A O      1 
ATOM   4672 C CB     . THR B 2 292 ? 46.890 14.412  15.202 1.00 2.02  ? 292 THR A CB     1 
ATOM   4673 O OG1    . THR B 2 292 ? 47.106 13.025  14.996 1.00 2.01  ? 292 THR A OG1    1 
ATOM   4674 C CG2    . THR B 2 292 ? 47.860 14.870  16.236 1.00 2.01  ? 292 THR A CG2    1 
ATOM   4675 H H      . THR B 2 292 ? 45.932 13.328  17.260 1.00 20.00 ? 292 THR A H      1 
ATOM   4676 H HG1    . THR B 2 292 ? 48.057 12.884  14.727 1.00 20.00 ? 292 THR A HG1    1 
ATOM   4677 N N      . ILE B 2 293 ? 44.169 14.779  13.601 1.00 2.95  ? 293 ILE A N      1 
ATOM   4678 C CA     . ILE B 2 293 ? 43.282 14.335  12.527 1.00 2.00  ? 293 ILE A CA     1 
ATOM   4679 C C      . ILE B 2 293 ? 43.926 13.146  11.838 1.00 2.00  ? 293 ILE A C      1 
ATOM   4680 O O      . ILE B 2 293 ? 43.236 12.202  11.542 1.00 2.00  ? 293 ILE A O      1 
ATOM   4681 C CB     . ILE B 2 293 ? 43.104 15.387  11.421 1.00 2.00  ? 293 ILE A CB     1 
ATOM   4682 C CG1    . ILE B 2 293 ? 42.383 16.605  11.952 1.00 2.01  ? 293 ILE A CG1    1 
ATOM   4683 C CG2    . ILE B 2 293 ? 42.295 14.837  10.313 1.00 2.00  ? 293 ILE A CG2    1 
ATOM   4684 C CD1    . ILE B 2 293 ? 40.951 16.329  12.278 1.00 5.85  ? 293 ILE A CD1    1 
ATOM   4685 H H      . ILE B 2 293 ? 44.567 15.685  13.567 1.00 20.00 ? 293 ILE A H      1 
ATOM   4686 N N      . SER B 2 294 ? 45.231 13.192  11.566 1.00 2.00  ? 294 SER A N      1 
ATOM   4687 C CA     . SER B 2 294 ? 45.853 12.074  10.870 1.00 2.00  ? 294 SER A CA     1 
ATOM   4688 C C      . SER B 2 294 ? 45.869 10.843  11.764 1.00 2.00  ? 294 SER A C      1 
ATOM   4689 O O      . SER B 2 294 ? 45.675 9.727   11.299 1.00 2.00  ? 294 SER A O      1 
ATOM   4690 C CB     . SER B 2 294 ? 47.256 12.416  10.351 1.00 2.01  ? 294 SER A CB     1 
ATOM   4691 O OG     . SER B 2 294 ? 48.226 12.272  11.366 1.00 2.01  ? 294 SER A OG     1 
ATOM   4692 H H      . SER B 2 294 ? 45.786 13.948  11.856 1.00 20.00 ? 294 SER A H      1 
ATOM   4693 H HG     . SER B 2 294 ? 49.105 12.507  10.991 1.00 20.00 ? 294 SER A HG     1 
ATOM   4694 N N      . GLY B 2 295 ? 46.058 11.053  13.056 1.00 2.00  ? 295 GLY A N      1 
ATOM   4695 C CA     . GLY B 2 295 ? 46.065 9.939   13.985 1.00 2.01  ? 295 GLY A CA     1 
ATOM   4696 C C      . GLY B 2 295 ? 44.674 9.350   14.025 1.00 2.01  ? 295 GLY A C      1 
ATOM   4697 O O      . GLY B 2 295 ? 44.526 8.140   13.946 1.00 2.00  ? 295 GLY A O      1 
ATOM   4698 H H      . GLY B 2 295 ? 46.160 11.949  13.407 1.00 20.00 ? 295 GLY A H      1 
ATOM   4699 N N      . LEU B 2 296 ? 43.651 10.201  14.088 1.00 2.00  ? 296 LEU A N      1 
ATOM   4700 C CA     . LEU B 2 296 ? 42.260 9.751   14.115 1.00 2.01  ? 296 LEU A CA     1 
ATOM   4701 C C      . LEU B 2 296 ? 41.973 8.914   12.868 1.00 2.00  ? 296 LEU A C      1 
ATOM   4702 O O      . LEU B 2 296 ? 41.344 7.868   12.927 1.00 2.00  ? 296 LEU A O      1 
ATOM   4703 C CB     . LEU B 2 296 ? 41.326 10.956  14.175 1.00 2.00  ? 296 LEU A CB     1 
ATOM   4704 C CG     . LEU B 2 296 ? 41.216 11.679  15.521 1.00 2.00  ? 296 LEU A CG     1 
ATOM   4705 C CD1    . LEU B 2 296 ? 40.332 12.916  15.436 1.00 2.01  ? 296 LEU A CD1    1 
ATOM   4706 C CD2    . LEU B 2 296 ? 40.616 10.705  16.523 1.00 2.01  ? 296 LEU A CD2    1 
ATOM   4707 H H      . LEU B 2 296 ? 43.849 11.146  14.119 1.00 20.00 ? 296 LEU A H      1 
ATOM   4708 N N      . ARG B 2 297 ? 42.493 9.372   11.737 1.00 2.00  ? 297 ARG A N      1 
ATOM   4709 C CA     . ARG B 2 297 ? 42.340 8.691   10.464 1.00 2.00  ? 297 ARG A CA     1 
ATOM   4710 C C      . ARG B 2 297 ? 42.913 7.275   10.582 1.00 2.72  ? 297 ARG A C      1 
ATOM   4711 O O      . ARG B 2 297 ? 42.193 6.301   10.374 1.00 2.00  ? 297 ARG A O      1 
ATOM   4712 C CB     . ARG B 2 297 ? 43.116 9.445   9.401  1.00 3.29  ? 297 ARG A CB     1 
ATOM   4713 C CG     . ARG B 2 297 ? 42.855 9.015   8.003  1.00 8.79  ? 297 ARG A CG     1 
ATOM   4714 C CD     . ARG B 2 297 ? 44.001 9.465   7.122  1.00 15.76 ? 297 ARG A CD     1 
ATOM   4715 N NE     . ARG B 2 297 ? 43.971 10.892  6.806  1.00 20.20 ? 297 ARG A NE     1 
ATOM   4716 C CZ     . ARG B 2 297 ? 44.996 11.725  6.980  1.00 24.24 ? 297 ARG A CZ     1 
ATOM   4717 N NH1    . ARG B 2 297 ? 46.132 11.306  7.537  1.00 25.38 ? 297 ARG A NH1    1 
ATOM   4718 N NH2    . ARG B 2 297 ? 44.863 12.995  6.636  1.00 23.88 ? 297 ARG A NH2    1 
ATOM   4719 H H      . ARG B 2 297 ? 43.057 10.189  11.776 1.00 20.00 ? 297 ARG A H      1 
ATOM   4720 H HE     . ARG B 2 297 ? 43.148 11.264  6.454  1.00 20.00 ? 297 ARG A HE     1 
ATOM   4721 H HH11   . ARG B 2 297 ? 46.235 10.358  7.830  1.00 20.00 ? 297 ARG A HH11   1 
ATOM   4722 H HH12   . ARG B 2 297 ? 46.897 11.948  7.661  1.00 20.00 ? 297 ARG A HH12   1 
ATOM   4723 H HH21   . ARG B 2 297 ? 44.012 13.339  6.269  1.00 20.00 ? 297 ARG A HH21   1 
ATOM   4724 H HH22   . ARG B 2 297 ? 45.643 13.623  6.773  1.00 20.00 ? 297 ARG A HH22   1 
ATOM   4725 N N      . ARG B 2 298 ? 44.198 7.170   10.944 1.00 4.24  ? 298 ARG A N      1 
ATOM   4726 C CA     . ARG B 2 298 ? 44.891 5.879   11.098 1.00 2.00  ? 298 ARG A CA     1 
ATOM   4727 C C      . ARG B 2 298 ? 44.197 4.997   12.114 1.00 4.61  ? 298 ARG A C      1 
ATOM   4728 O O      . ARG B 2 298 ? 44.202 3.761   12.005 1.00 4.42  ? 298 ARG A O      1 
ATOM   4729 C CB     . ARG B 2 298 ? 46.321 6.117   11.545 1.00 2.01  ? 298 ARG A CB     1 
ATOM   4730 C CG     . ARG B 2 298 ? 47.050 4.870   11.891 1.00 3.05  ? 298 ARG A CG     1 
ATOM   4731 C CD     . ARG B 2 298 ? 48.553 5.115   11.868 1.00 8.53  ? 298 ARG A CD     1 
ATOM   4732 N NE     . ARG B 2 298 ? 49.269 4.060   12.570 1.00 14.77 ? 298 ARG A NE     1 
ATOM   4733 C CZ     . ARG B 2 298 ? 50.556 4.104   12.898 1.00 17.01 ? 298 ARG A CZ     1 
ATOM   4734 N NH1    . ARG B 2 298 ? 51.314 5.136   12.543 1.00 20.36 ? 298 ARG A NH1    1 
ATOM   4735 N NH2    . ARG B 2 298 ? 51.094 3.085   13.558 1.00 17.66 ? 298 ARG A NH2    1 
ATOM   4736 H H      . ARG B 2 298 ? 44.709 7.995   11.141 1.00 20.00 ? 298 ARG A H      1 
ATOM   4737 H HE     . ARG B 2 298 ? 48.758 3.242   12.792 1.00 20.00 ? 298 ARG A HE     1 
ATOM   4738 H HH11   . ARG B 2 298 ? 50.911 5.890   12.043 1.00 20.00 ? 298 ARG A HH11   1 
ATOM   4739 H HH12   . ARG B 2 298 ? 52.273 5.145   12.816 1.00 20.00 ? 298 ARG A HH12   1 
ATOM   4740 H HH21   . ARG B 2 298 ? 50.528 2.271   13.774 1.00 20.00 ? 298 ARG A HH21   1 
ATOM   4741 H HH22   . ARG B 2 298 ? 52.048 3.084   13.791 1.00 20.00 ? 298 ARG A HH22   1 
ATOM   4742 N N      . ARG B 2 299 ? 43.578 5.654   13.086 1.00 5.03  ? 299 ARG A N      1 
ATOM   4743 C CA     . ARG B 2 299 ? 42.869 4.980   14.148 1.00 5.26  ? 299 ARG A CA     1 
ATOM   4744 C C      . ARG B 2 299 ? 41.666 4.348   13.511 1.00 3.16  ? 299 ARG A C      1 
ATOM   4745 O O      . ARG B 2 299 ? 41.101 3.392   14.045 1.00 5.76  ? 299 ARG A O      1 
ATOM   4746 C CB     . ARG B 2 299 ? 42.448 5.993   15.226 1.00 9.01  ? 299 ARG A CB     1 
ATOM   4747 C CG     . ARG B 2 299 ? 41.470 5.500   16.269 1.00 10.75 ? 299 ARG A CG     1 
ATOM   4748 C CD     . ARG B 2 299 ? 42.117 4.509   17.189 1.00 14.52 ? 299 ARG A CD     1 
ATOM   4749 N NE     . ARG B 2 299 ? 41.269 4.313   18.354 1.00 17.48 ? 299 ARG A NE     1 
ATOM   4750 C CZ     . ARG B 2 299 ? 41.516 4.847   19.539 1.00 19.86 ? 299 ARG A CZ     1 
ATOM   4751 N NH1    . ARG B 2 299 ? 42.599 5.581   19.723 1.00 22.65 ? 299 ARG A NH1    1 
ATOM   4752 N NH2    . ARG B 2 299 ? 40.693 4.630   20.545 1.00 18.05 ? 299 ARG A NH2    1 
ATOM   4753 H H      . ARG B 2 299 ? 43.646 6.625   13.140 1.00 20.00 ? 299 ARG A H      1 
ATOM   4754 H HE     . ARG B 2 299 ? 40.474 3.763   18.260 1.00 20.00 ? 299 ARG A HE     1 
ATOM   4755 H HH11   . ARG B 2 299 ? 43.253 5.715   18.983 1.00 20.00 ? 299 ARG A HH11   1 
ATOM   4756 H HH12   . ARG B 2 299 ? 42.797 5.963   20.631 1.00 20.00 ? 299 ARG A HH12   1 
ATOM   4757 H HH21   . ARG B 2 299 ? 39.880 4.063   20.418 1.00 20.00 ? 299 ARG A HH21   1 
ATOM   4758 H HH22   . ARG B 2 299 ? 40.883 5.026   21.447 1.00 20.00 ? 299 ARG A HH22   1 
ATOM   4759 N N      . GLY B 2 300 ? 41.261 4.912   12.378 1.00 2.41  ? 300 GLY A N      1 
ATOM   4760 C CA     . GLY B 2 300 ? 40.102 4.400   11.667 1.00 2.00  ? 300 GLY A CA     1 
ATOM   4761 C C      . GLY B 2 300 ? 38.821 5.230   11.719 1.00 2.00  ? 300 GLY A C      1 
ATOM   4762 O O      . GLY B 2 300 ? 37.706 4.728   11.454 1.00 2.00  ? 300 GLY A O      1 
ATOM   4763 H H      . GLY B 2 300 ? 41.731 5.709   12.065 1.00 20.00 ? 300 GLY A H      1 
ATOM   4764 N N      . TYR B 2 301 ? 38.947 6.489   12.125 1.00 2.00  ? 301 TYR A N      1 
ATOM   4765 C CA     . TYR B 2 301 ? 37.786 7.361   12.160 1.00 2.00  ? 301 TYR A CA     1 
ATOM   4766 C C      . TYR B 2 301 ? 37.505 7.723   10.725 1.00 2.00  ? 301 TYR A C      1 
ATOM   4767 O O      . TYR B 2 301 ? 38.329 7.463   9.828  1.00 2.00  ? 301 TYR A O      1 
ATOM   4768 C CB     . TYR B 2 301 ? 38.079 8.622   12.954 1.00 2.00  ? 301 TYR A CB     1 
ATOM   4769 C CG     . TYR B 2 301 ? 37.729 8.479   14.413 1.00 2.00  ? 301 TYR A CG     1 
ATOM   4770 C CD1    . TYR B 2 301 ? 38.528 7.710   15.258 1.00 2.00  ? 301 TYR A CD1    1 
ATOM   4771 C CD2    . TYR B 2 301 ? 36.569 9.042   14.939 1.00 2.01  ? 301 TYR A CD2    1 
ATOM   4772 C CE1    . TYR B 2 301 ? 38.175 7.498   16.587 1.00 2.00  ? 301 TYR A CE1    1 
ATOM   4773 C CE2    . TYR B 2 301 ? 36.215 8.834   16.255 1.00 2.01  ? 301 TYR A CE2    1 
ATOM   4774 C CZ     . TYR B 2 301 ? 37.020 8.063   17.072 1.00 2.02  ? 301 TYR A CZ     1 
ATOM   4775 O OH     . TYR B 2 301 ? 36.693 7.849   18.391 1.00 4.24  ? 301 TYR A OH     1 
ATOM   4776 H H      . TYR B 2 301 ? 39.821 6.829   12.372 1.00 20.00 ? 301 TYR A H      1 
ATOM   4777 H HH     . TYR B 2 301 ? 37.350 7.317   18.805 1.00 20.00 ? 301 TYR A HH     1 
ATOM   4778 N N      . THR B 2 302 ? 36.356 8.330   10.492 1.00 2.00  ? 302 THR A N      1 
ATOM   4779 C CA     . THR B 2 302 ? 36.018 8.736   9.147  1.00 2.00  ? 302 THR A CA     1 
ATOM   4780 C C      . THR B 2 302 ? 35.756 10.239  9.045  1.00 2.01  ? 302 THR A C      1 
ATOM   4781 O O      . THR B 2 302 ? 35.140 10.830  9.924  1.00 2.01  ? 302 THR A O      1 
ATOM   4782 C CB     . THR B 2 302 ? 34.826 7.936   8.628  1.00 2.00  ? 302 THR A CB     1 
ATOM   4783 O OG1    . THR B 2 302 ? 33.751 8.015   9.561  1.00 2.01  ? 302 THR A OG1    1 
ATOM   4784 C CG2    . THR B 2 302 ? 35.232 6.483   8.455  1.00 2.00  ? 302 THR A CG2    1 
ATOM   4785 H H      . THR B 2 302 ? 35.715 8.461   11.196 1.00 20.00 ? 302 THR A H      1 
ATOM   4786 H HG1    . THR B 2 302 ? 33.058 7.481   9.218  1.00 20.00 ? 302 THR A HG1    1 
ATOM   4787 N N      . ALA B 2 303 ? 36.258 10.862  7.985  1.00 2.39  ? 303 ALA A N      1 
ATOM   4788 C CA     . ALA B 2 303 ? 36.058 12.283  7.802  1.00 2.01  ? 303 ALA A CA     1 
ATOM   4789 C C      . ALA B 2 303 ? 34.597 12.627  8.051  1.00 2.01  ? 303 ALA A C      1 
ATOM   4790 O O      . ALA B 2 303 ? 34.289 13.618  8.689  1.00 7.71  ? 303 ALA A O      1 
ATOM   4791 C CB     . ALA B 2 303 ? 36.469 12.698  6.411  1.00 5.52  ? 303 ALA A CB     1 
ATOM   4792 H H      . ALA B 2 303 ? 36.749 10.340  7.280  1.00 20.00 ? 303 ALA A H      1 
ATOM   4793 N N      . ALA B 2 304 ? 33.690 11.756  7.659  1.00 2.01  ? 304 ALA A N      1 
ATOM   4794 C CA     . ALA B 2 304 ? 32.291 12.069  7.883  1.00 3.41  ? 304 ALA A CA     1 
ATOM   4795 C C      . ALA B 2 304 ? 31.890 12.024  9.354  1.00 6.34  ? 304 ALA A C      1 
ATOM   4796 O O      . ALA B 2 304 ? 30.954 12.723  9.762  1.00 7.38  ? 304 ALA A O      1 
ATOM   4797 C CB     . ALA B 2 304 ? 31.401 11.175  7.061  1.00 6.19  ? 304 ALA A CB     1 
ATOM   4798 H H      . ALA B 2 304 ? 33.940 10.924  7.227  1.00 20.00 ? 304 ALA A H      1 
ATOM   4799 N N      . SER B 2 305 ? 32.561 11.191  10.142 1.00 7.01  ? 305 SER A N      1 
ATOM   4800 C CA     . SER B 2 305 ? 32.230 11.107  11.553 1.00 3.65  ? 305 SER A CA     1 
ATOM   4801 C C      . SER B 2 305 ? 32.712 12.352  12.272 1.00 3.10  ? 305 SER A C      1 
ATOM   4802 O O      . SER B 2 305 ? 32.073 12.812  13.220 1.00 3.43  ? 305 SER A O      1 
ATOM   4803 C CB     . SER B 2 305 ? 32.851 9.874   12.193 1.00 3.26  ? 305 SER A CB     1 
ATOM   4804 O OG     . SER B 2 305 ? 34.260 9.890   12.039 1.00 6.50  ? 305 SER A OG     1 
ATOM   4805 H H      . SER B 2 305 ? 33.270 10.626  9.792  1.00 20.00 ? 305 SER A H      1 
ATOM   4806 H HG     . SER B 2 305 ? 34.620 9.104   12.441 1.00 20.00 ? 305 SER A HG     1 
ATOM   4807 N N      . ILE B 2 306 ? 33.844 12.902  11.835 1.00 3.33  ? 306 ILE A N      1 
ATOM   4808 C CA     . ILE B 2 306 ? 34.401 14.109  12.473 1.00 2.00  ? 306 ILE A CA     1 
ATOM   4809 C C      . ILE B 2 306 ? 33.506 15.303  12.156 1.00 2.17  ? 306 ILE A C      1 
ATOM   4810 O O      . ILE B 2 306 ? 33.149 16.059  13.050 1.00 2.00  ? 306 ILE A O      1 
ATOM   4811 C CB     . ILE B 2 306 ? 35.883 14.307  12.068 1.00 2.00  ? 306 ILE A CB     1 
ATOM   4812 C CG1    . ILE B 2 306 ? 36.734 13.297  12.842 1.00 2.00  ? 306 ILE A CG1    1 
ATOM   4813 C CG2    . ILE B 2 306 ? 36.361 15.723  12.319 1.00 2.01  ? 306 ILE A CG2    1 
ATOM   4814 C CD1    . ILE B 2 306 ? 38.159 13.156  12.327 1.00 2.00  ? 306 ILE A CD1    1 
ATOM   4815 H H      . ILE B 2 306 ? 34.326 12.466  11.095 1.00 20.00 ? 306 ILE A H      1 
ATOM   4816 N N      . ARG B 2 307 ? 33.085 15.426  10.905 1.00 2.00  ? 307 ARG A N      1 
ATOM   4817 C CA     . ARG B 2 307 ? 32.188 16.507  10.544 1.00 5.44  ? 307 ARG A CA     1 
ATOM   4818 C C      . ARG B 2 307 ? 30.938 16.461  11.438 1.00 8.04  ? 307 ARG A C      1 
ATOM   4819 O O      . ARG B 2 307 ? 30.394 17.501  11.850 1.00 8.22  ? 307 ARG A O      1 
ATOM   4820 C CB     . ARG B 2 307 ? 31.748 16.384  9.094  1.00 7.46  ? 307 ARG A CB     1 
ATOM   4821 C CG     . ARG B 2 307 ? 32.805 16.717  8.085  1.00 10.80 ? 307 ARG A CG     1 
ATOM   4822 C CD     . ARG B 2 307 ? 32.236 16.609  6.703  1.00 11.88 ? 307 ARG A CD     1 
ATOM   4823 N NE     . ARG B 2 307 ? 33.049 15.688  5.929  1.00 14.84 ? 307 ARG A NE     1 
ATOM   4824 C CZ     . ARG B 2 307 ? 32.573 14.607  5.325  1.00 17.80 ? 307 ARG A CZ     1 
ATOM   4825 N NH1    . ARG B 2 307 ? 31.278 14.325  5.397  1.00 20.26 ? 307 ARG A NH1    1 
ATOM   4826 N NH2    . ARG B 2 307 ? 33.393 13.813  4.640  1.00 20.22 ? 307 ARG A NH2    1 
ATOM   4827 H H      . ARG B 2 307 ? 33.400 14.812  10.206 1.00 20.00 ? 307 ARG A H      1 
ATOM   4828 H HE     . ARG B 2 307 ? 34.000 15.880  5.833  1.00 20.00 ? 307 ARG A HE     1 
ATOM   4829 H HH11   . ARG B 2 307 ? 30.661 14.907  5.921  1.00 20.00 ? 307 ARG A HH11   1 
ATOM   4830 H HH12   . ARG B 2 307 ? 30.929 13.490  4.966  1.00 20.00 ? 307 ARG A HH12   1 
ATOM   4831 H HH21   . ARG B 2 307 ? 34.369 14.041  4.574  1.00 20.00 ? 307 ARG A HH21   1 
ATOM   4832 H HH22   . ARG B 2 307 ? 33.045 12.992  4.195  1.00 20.00 ? 307 ARG A HH22   1 
ATOM   4833 N N      . GLU B 2 308 ? 30.465 15.253  11.720 1.00 11.44 ? 308 GLU A N      1 
ATOM   4834 C CA     . GLU B 2 308 ? 29.295 15.093  12.569 1.00 12.22 ? 308 GLU A CA     1 
ATOM   4835 C C      . GLU B 2 308 ? 29.644 15.606  13.962 1.00 9.02  ? 308 GLU A C      1 
ATOM   4836 O O      . GLU B 2 308 ? 28.883 16.377  14.549 1.00 10.82 ? 308 GLU A O      1 
ATOM   4837 C CB     . GLU B 2 308 ? 28.872 13.628  12.633 1.00 17.57 ? 308 GLU A CB     1 
ATOM   4838 C CG     . GLU B 2 308 ? 27.755 13.325  13.633 1.00 21.26 ? 308 GLU A CG     1 
ATOM   4839 C CD     . GLU B 2 308 ? 26.414 13.961  13.261 1.00 24.79 ? 308 GLU A CD     1 
ATOM   4840 O OE1    . GLU B 2 308 ? 26.276 14.496  12.139 1.00 27.16 ? 308 GLU A OE1    1 
ATOM   4841 O OE2    . GLU B 2 308 ? 25.483 13.931  14.088 1.00 23.06 ? 308 GLU A OE2    1 
ATOM   4842 H H      . GLU B 2 308 ? 30.925 14.455  11.362 1.00 20.00 ? 308 GLU A H      1 
ATOM   4843 N N      . PHE B 2 309 ? 30.811 15.212  14.467 1.00 5.29  ? 309 PHE A N      1 
ATOM   4844 C CA     . PHE B 2 309 ? 31.258 15.662  15.782 1.00 2.61  ? 309 PHE A CA     1 
ATOM   4845 C C      . PHE B 2 309 ? 31.179 17.201  15.845 1.00 3.01  ? 309 PHE A C      1 
ATOM   4846 O O      . PHE B 2 309 ? 30.515 17.755  16.726 1.00 3.19  ? 309 PHE A O      1 
ATOM   4847 C CB     . PHE B 2 309 ? 32.680 15.176  16.069 1.00 2.00  ? 309 PHE A CB     1 
ATOM   4848 C CG     . PHE B 2 309 ? 33.188 15.559  17.428 1.00 2.00  ? 309 PHE A CG     1 
ATOM   4849 C CD1    . PHE B 2 309 ? 32.445 15.282  18.556 1.00 2.00  ? 309 PHE A CD1    1 
ATOM   4850 C CD2    . PHE B 2 309 ? 34.425 16.183  17.573 1.00 3.01  ? 309 PHE A CD2    1 
ATOM   4851 C CE1    . PHE B 2 309 ? 32.911 15.609  19.804 1.00 2.00  ? 309 PHE A CE1    1 
ATOM   4852 C CE2    . PHE B 2 309 ? 34.922 16.529  18.837 1.00 3.09  ? 309 PHE A CE2    1 
ATOM   4853 C CZ     . PHE B 2 309 ? 34.156 16.236  19.955 1.00 2.43  ? 309 PHE A CZ     1 
ATOM   4854 H H      . PHE B 2 309 ? 31.422 14.672  13.907 1.00 20.00 ? 309 PHE A H      1 
ATOM   4855 N N      . CYS B 2 310 ? 31.799 17.885  14.886 1.00 3.65  ? 310 CYS A N      1 
ATOM   4856 C CA     . CYS B 2 310 ? 31.746 19.326  14.853 1.00 4.87  ? 310 CYS A CA     1 
ATOM   4857 C C      . CYS B 2 310 ? 30.286 19.740  14.832 1.00 5.19  ? 310 CYS A C      1 
ATOM   4858 O O      . CYS B 2 310 ? 29.858 20.567  15.624 1.00 2.00  ? 310 CYS A O      1 
ATOM   4859 C CB     . CYS B 2 310 ? 32.420 19.831  13.604 1.00 10.20 ? 310 CYS A CB     1 
ATOM   4860 S SG     . CYS B 2 310 ? 34.162 19.594  13.643 1.00 8.59  ? 310 CYS A SG     1 
ATOM   4861 H H      . CYS B 2 310 ? 32.313 17.404  14.183 1.00 20.00 ? 310 CYS A H      1 
ATOM   4862 N N      . LYS B 2 311 ? 29.500 19.152  13.948 1.00 6.41  ? 311 LYS A N      1 
ATOM   4863 C CA     . LYS B 2 311 ? 28.101 19.511  13.884 1.00 10.54 ? 311 LYS A CA     1 
ATOM   4864 C C      . LYS B 2 311 ? 27.486 19.465  15.278 1.00 9.56  ? 311 LYS A C      1 
ATOM   4865 O O      . LYS B 2 311 ? 26.752 20.373  15.671 1.00 8.03  ? 311 LYS A O      1 
ATOM   4866 C CB     . LYS B 2 311 ? 27.358 18.545  12.976 1.00 16.50 ? 311 LYS A CB     1 
ATOM   4867 C CG     . LYS B 2 311 ? 26.037 19.076  12.454 1.00 20.65 ? 311 LYS A CG     1 
ATOM   4868 C CD     . LYS B 2 311 ? 26.157 19.552  11.010 1.00 24.97 ? 311 LYS A CD     1 
ATOM   4869 C CE     . LYS B 2 311 ? 26.031 18.399  10.008 1.00 26.14 ? 311 LYS A CE     1 
ATOM   4870 N NZ     . LYS B 2 311 ? 27.325 17.743  9.612  1.00 27.13 ? 311 LYS A NZ     1 
ATOM   4871 H H      . LYS B 2 311 ? 29.858 18.508  13.325 1.00 20.00 ? 311 LYS A H      1 
ATOM   4872 H HZ1    . LYS B 2 311 ? 27.905 17.537  10.450 1.00 20.00 ? 311 LYS A HZ1    1 
ATOM   4873 H HZ2    . LYS B 2 311 ? 27.097 16.819  9.144  1.00 20.00 ? 311 LYS A HZ2    1 
ATOM   4874 H HZ3    . LYS B 2 311 ? 27.845 18.329  8.945  1.00 20.00 ? 311 LYS A HZ3    1 
ATOM   4875 N N      . ARG B 2 312 ? 27.860 18.446  16.051 1.00 9.62  ? 312 ARG A N      1 
ATOM   4876 C CA     . ARG B 2 312 ? 27.297 18.246  17.385 1.00 8.77  ? 312 ARG A CA     1 
ATOM   4877 C C      . ARG B 2 312 ? 27.740 19.149  18.525 1.00 6.54  ? 312 ARG A C      1 
ATOM   4878 O O      . ARG B 2 312 ? 26.899 19.615  19.288 1.00 5.16  ? 312 ARG A O      1 
ATOM   4879 C CB     . ARG B 2 312 ? 27.443 16.798  17.808 1.00 10.14 ? 312 ARG A CB     1 
ATOM   4880 C CG     . ARG B 2 312 ? 26.713 15.808  16.947 1.00 14.41 ? 312 ARG A CG     1 
ATOM   4881 C CD     . ARG B 2 312 ? 27.013 14.426  17.469 1.00 16.79 ? 312 ARG A CD     1 
ATOM   4882 N NE     . ARG B 2 312 ? 26.336 13.377  16.725 1.00 19.27 ? 312 ARG A NE     1 
ATOM   4883 C CZ     . ARG B 2 312 ? 26.308 12.106  17.105 1.00 19.78 ? 312 ARG A CZ     1 
ATOM   4884 N NH1    . ARG B 2 312 ? 26.927 11.739  18.234 1.00 19.91 ? 312 ARG A NH1    1 
ATOM   4885 N NH2    . ARG B 2 312 ? 25.665 11.212  16.366 1.00 19.59 ? 312 ARG A NH2    1 
ATOM   4886 H H      . ARG B 2 312 ? 28.492 17.797  15.710 1.00 20.00 ? 312 ARG A H      1 
ATOM   4887 H HE     . ARG B 2 312 ? 25.853 13.616  15.939 1.00 20.00 ? 312 ARG A HE     1 
ATOM   4888 H HH11   . ARG B 2 312 ? 27.396 12.426  18.803 1.00 20.00 ? 312 ARG A HH11   1 
ATOM   4889 H HH12   . ARG B 2 312 ? 26.928 10.784  18.532 1.00 20.00 ? 312 ARG A HH12   1 
ATOM   4890 H HH21   . ARG B 2 312 ? 25.212 11.478  15.534 1.00 20.00 ? 312 ARG A HH21   1 
ATOM   4891 H HH22   . ARG B 2 312 ? 25.677 10.244  16.659 1.00 20.00 ? 312 ARG A HH22   1 
ATOM   4892 N N      . ILE B 2 313 ? 29.040 19.362  18.685 1.00 4.16  ? 313 ILE A N      1 
ATOM   4893 C CA     . ILE B 2 313 ? 29.512 20.204  19.785 1.00 2.65  ? 313 ILE A CA     1 
ATOM   4894 C C      . ILE B 2 313 ? 29.043 21.679  19.795 1.00 3.59  ? 313 ILE A C      1 
ATOM   4895 O O      . ILE B 2 313 ? 29.066 22.333  20.845 1.00 6.12  ? 313 ILE A O      1 
ATOM   4896 C CB     . ILE B 2 313 ? 31.028 20.100  19.956 1.00 5.60  ? 313 ILE A CB     1 
ATOM   4897 C CG1    . ILE B 2 313 ? 31.743 20.583  18.710 1.00 2.01  ? 313 ILE A CG1    1 
ATOM   4898 C CG2    . ILE B 2 313 ? 31.413 18.666  20.176 1.00 2.00  ? 313 ILE A CG2    1 
ATOM   4899 C CD1    . ILE B 2 313 ? 33.220 20.384  18.781 1.00 2.00  ? 313 ILE A CD1    1 
ATOM   4900 H H      . ILE B 2 313 ? 29.676 19.001  18.032 1.00 20.00 ? 313 ILE A H      1 
ATOM   4901 N N      . GLY B 2 314 ? 28.592 22.186  18.648 1.00 5.08  ? 314 GLY A N      1 
ATOM   4902 C CA     . GLY B 2 314 ? 28.114 23.567  18.569 1.00 5.58  ? 314 GLY A CA     1 
ATOM   4903 C C      . GLY B 2 314 ? 29.215 24.617  18.482 1.00 6.56  ? 314 GLY A C      1 
ATOM   4904 O O      . GLY B 2 314 ? 30.394 24.299  18.288 1.00 10.46 ? 314 GLY A O      1 
ATOM   4905 H H      . GLY B 2 314 ? 28.611 21.638  17.838 1.00 20.00 ? 314 GLY A H      1 
ATOM   4906 N N      . VAL B 2 315 ? 28.819 25.883  18.546 1.00 3.94  ? 315 VAL A N      1 
ATOM   4907 C CA     . VAL B 2 315 ? 29.778 26.976  18.505 1.00 2.00  ? 315 VAL A CA     1 
ATOM   4908 C C      . VAL B 2 315 ? 29.252 28.049  19.453 1.00 2.01  ? 315 VAL A C      1 
ATOM   4909 O O      . VAL B 2 315 ? 28.184 28.595  19.231 1.00 2.01  ? 315 VAL A O      1 
ATOM   4910 C CB     . VAL B 2 315 ? 29.933 27.516  17.086 1.00 2.01  ? 315 VAL A CB     1 
ATOM   4911 C CG1    . VAL B 2 315 ? 30.699 28.808  17.098 1.00 2.00  ? 315 VAL A CG1    1 
ATOM   4912 C CG2    . VAL B 2 315 ? 30.668 26.506  16.244 1.00 2.00  ? 315 VAL A CG2    1 
ATOM   4913 H H      . VAL B 2 315 ? 27.863 26.115  18.600 1.00 20.00 ? 315 VAL A H      1 
ATOM   4914 N N      . THR B 2 316 ? 29.951 28.295  20.556 1.00 2.00  ? 316 THR A N      1 
ATOM   4915 C CA     . THR B 2 316 ? 29.503 29.290  21.529 1.00 2.00  ? 316 THR A CA     1 
ATOM   4916 C C      . THR B 2 316 ? 30.706 30.017  22.146 1.00 2.61  ? 316 THR A C      1 
ATOM   4917 O O      . THR B 2 316 ? 31.847 29.776  21.724 1.00 2.00  ? 316 THR A O      1 
ATOM   4918 C CB     . THR B 2 316 ? 28.790 28.592  22.651 1.00 2.01  ? 316 THR A CB     1 
ATOM   4919 O OG1    . THR B 2 316 ? 29.721 27.719  23.276 1.00 2.01  ? 316 THR A OG1    1 
ATOM   4920 C CG2    . THR B 2 316 ? 27.675 27.757  22.131 1.00 2.00  ? 316 THR A CG2    1 
ATOM   4921 H H      . THR B 2 316 ? 30.798 27.828  20.706 1.00 20.00 ? 316 THR A H      1 
ATOM   4922 H HG1    . THR B 2 316 ? 29.279 27.232  23.990 1.00 20.00 ? 316 THR A HG1    1 
ATOM   4923 N N      . LYS B 2 317 ? 30.451 30.926  23.100 1.00 2.00  ? 317 LYS A N      1 
ATOM   4924 C CA     . LYS B 2 317 ? 31.503 31.669  23.806 1.00 2.50  ? 317 LYS A CA     1 
ATOM   4925 C C      . LYS B 2 317 ? 31.782 30.933  25.118 1.00 4.50  ? 317 LYS A C      1 
ATOM   4926 O O      . LYS B 2 317 ? 32.607 31.345  25.936 1.00 6.50  ? 317 LYS A O      1 
ATOM   4927 C CB     . LYS B 2 317 ? 31.010 33.057  24.192 1.00 6.54  ? 317 LYS A CB     1 
ATOM   4928 C CG     . LYS B 2 317 ? 30.599 33.925  23.064 1.00 12.48 ? 317 LYS A CG     1 
ATOM   4929 C CD     . LYS B 2 317 ? 31.803 34.409  22.330 1.00 16.92 ? 317 LYS A CD     1 
ATOM   4930 C CE     . LYS B 2 317 ? 31.822 35.935  22.240 1.00 18.79 ? 317 LYS A CE     1 
ATOM   4931 N NZ     . LYS B 2 317 ? 31.986 36.604  23.580 1.00 18.62 ? 317 LYS A NZ     1 
ATOM   4932 H H      . LYS B 2 317 ? 29.512 31.096  23.360 1.00 20.00 ? 317 LYS A H      1 
ATOM   4933 H HZ1    . LYS B 2 317 ? 32.757 36.155  24.080 1.00 20.00 ? 317 LYS A HZ1    1 
ATOM   4934 H HZ2    . LYS B 2 317 ? 32.216 37.616  23.399 1.00 20.00 ? 317 LYS A HZ2    1 
ATOM   4935 H HZ3    . LYS B 2 317 ? 31.100 36.554  24.110 1.00 20.00 ? 317 LYS A HZ3    1 
ATOM   4936 N N      . GLN B 2 318 ? 31.048 29.853  25.328 1.00 8.16  ? 318 GLN A N      1 
ATOM   4937 C CA     . GLN B 2 318 ? 31.116 29.066  26.543 1.00 11.19 ? 318 GLN A CA     1 
ATOM   4938 C C      . GLN B 2 318 ? 32.347 28.205  26.599 1.00 9.32  ? 318 GLN A C      1 
ATOM   4939 O O      . GLN B 2 318 ? 32.615 27.502  25.644 1.00 7.15  ? 318 GLN A O      1 
ATOM   4940 C CB     . GLN B 2 318 ? 29.890 28.152  26.556 1.00 18.14 ? 318 GLN A CB     1 
ATOM   4941 C CG     . GLN B 2 318 ? 29.359 27.777  27.911 1.00 27.19 ? 318 GLN A CG     1 
ATOM   4942 C CD     . GLN B 2 318 ? 28.549 28.886  28.507 1.00 32.98 ? 318 GLN A CD     1 
ATOM   4943 O OE1    . GLN B 2 318 ? 28.014 29.733  27.779 1.00 35.10 ? 318 GLN A OE1    1 
ATOM   4944 N NE2    . GLN B 2 318 ? 28.456 28.907  29.828 1.00 37.16 ? 318 GLN A NE2    1 
ATOM   4945 H H      . GLN B 2 318 ? 30.428 29.585  24.652 1.00 20.00 ? 318 GLN A H      1 
ATOM   4946 H HE21   . GLN B 2 318 ? 27.930 29.603  30.207 1.00 20.00 ? 318 GLN A HE21   1 
ATOM   4947 H HE22   . GLN B 2 318 ? 28.883 28.220  30.343 1.00 20.00 ? 318 GLN A HE22   1 
ATOM   4948 N N      . ASP B 2 319 ? 33.096 28.247  27.697 1.00 10.61 ? 319 ASP A N      1 
ATOM   4949 C CA     . ASP B 2 319 ? 34.261 27.365  27.825 1.00 13.38 ? 319 ASP A CA     1 
ATOM   4950 C C      . ASP B 2 319 ? 33.654 25.975  27.986 1.00 9.95  ? 319 ASP A C      1 
ATOM   4951 O O      . ASP B 2 319 ? 32.566 25.848  28.533 1.00 9.72  ? 319 ASP A O      1 
ATOM   4952 C CB     . ASP B 2 319 ? 35.099 27.749  29.034 1.00 21.20 ? 319 ASP A CB     1 
ATOM   4953 C CG     . ASP B 2 319 ? 36.075 28.888  28.726 1.00 28.92 ? 319 ASP A CG     1 
ATOM   4954 O OD1    . ASP B 2 319 ? 35.643 29.967  28.233 1.00 32.25 ? 319 ASP A OD1    1 
ATOM   4955 O OD2    . ASP B 2 319 ? 37.293 28.695  28.968 1.00 32.59 ? 319 ASP A OD2    1 
ATOM   4956 H H      . ASP B 2 319 ? 32.889 28.890  28.409 1.00 20.00 ? 319 ASP A H      1 
ATOM   4957 N N      . ASN B 2 320 ? 34.334 24.930  27.542 1.00 7.02  ? 320 ASN A N      1 
ATOM   4958 C CA     . ASN B 2 320 ? 33.708 23.615  27.617 1.00 2.00  ? 320 ASN A CA     1 
ATOM   4959 C C      . ASN B 2 320 ? 34.675 22.459  27.492 1.00 2.00  ? 320 ASN A C      1 
ATOM   4960 O O      . ASN B 2 320 ? 35.768 22.622  26.957 1.00 2.01  ? 320 ASN A O      1 
ATOM   4961 C CB     . ASN B 2 320 ? 32.776 23.485  26.430 1.00 2.01  ? 320 ASN A CB     1 
ATOM   4962 C CG     . ASN B 2 320 ? 33.521 23.606  25.145 1.00 2.00  ? 320 ASN A CG     1 
ATOM   4963 O OD1    . ASN B 2 320 ? 34.065 22.631  24.628 1.00 2.01  ? 320 ASN A OD1    1 
ATOM   4964 N ND2    . ASN B 2 320 ? 33.687 24.831  24.687 1.00 3.03  ? 320 ASN A ND2    1 
ATOM   4965 H H      . ASN B 2 320 ? 35.235 25.010  27.196 1.00 20.00 ? 320 ASN A H      1 
ATOM   4966 H HD21   . ASN B 2 320 ? 34.224 24.935  23.837 1.00 20.00 ? 320 ASN A HD21   1 
ATOM   4967 H HD22   . ASN B 2 320 ? 33.348 25.608  25.153 1.00 20.00 ? 320 ASN A HD22   1 
ATOM   4968 N N      . THR B 2 321 ? 34.226 21.275  27.893 1.00 2.01  ? 321 THR A N      1 
ATOM   4969 C CA     . THR B 2 321 ? 35.014 20.056  27.755 1.00 2.00  ? 321 THR A CA     1 
ATOM   4970 C C      . THR B 2 321 ? 34.102 18.881  27.369 1.00 2.74  ? 321 THR A C      1 
ATOM   4971 O O      . THR B 2 321 ? 33.197 18.475  28.109 1.00 2.00  ? 321 THR A O      1 
ATOM   4972 C CB     . THR B 2 321 ? 35.798 19.723  28.995 1.00 3.16  ? 321 THR A CB     1 
ATOM   4973 O OG1    . THR B 2 321 ? 36.747 20.769  29.249 1.00 5.62  ? 321 THR A OG1    1 
ATOM   4974 C CG2    . THR B 2 321 ? 36.549 18.411  28.769 1.00 2.00  ? 321 THR A CG2    1 
ATOM   4975 H H      . THR B 2 321 ? 33.337 21.189  28.287 1.00 20.00 ? 321 THR A H      1 
ATOM   4976 H HG1    . THR B 2 321 ? 37.276 20.534  30.031 1.00 20.00 ? 321 THR A HG1    1 
ATOM   4977 N N      . ILE B 2 322 ? 34.298 18.398  26.156 1.00 5.67  ? 322 ILE A N      1 
ATOM   4978 C CA     . ILE B 2 322 ? 33.501 17.302  25.648 1.00 7.37  ? 322 ILE A CA     1 
ATOM   4979 C C      . ILE B 2 322 ? 34.054 15.958  26.114 1.00 7.24  ? 322 ILE A C      1 
ATOM   4980 O O      . ILE B 2 322 ? 35.283 15.764  26.209 1.00 10.28 ? 322 ILE A O      1 
ATOM   4981 C CB     . ILE B 2 322 ? 33.465 17.368  24.119 1.00 10.54 ? 322 ILE A CB     1 
ATOM   4982 C CG1    . ILE B 2 322 ? 32.531 18.490  23.678 1.00 10.87 ? 322 ILE A CG1    1 
ATOM   4983 C CG2    . ILE B 2 322 ? 33.032 16.049  23.517 1.00 13.49 ? 322 ILE A CG2    1 
ATOM   4984 C CD1    . ILE B 2 322 ? 33.128 19.813  23.824 1.00 13.99 ? 322 ILE A CD1    1 
ATOM   4985 H H      . ILE B 2 322 ? 35.023 18.766  25.610 1.00 20.00 ? 322 ILE A H      1 
ATOM   4986 N N      . GLU B 2 323 ? 33.150 15.034  26.410 1.00 3.84  ? 323 GLU A N      1 
ATOM   4987 C CA     . GLU B 2 323 ? 33.564 13.728  26.864 1.00 5.41  ? 323 GLU A CA     1 
ATOM   4988 C C      . GLU B 2 323 ? 33.818 12.910  25.632 1.00 7.50  ? 323 GLU A C      1 
ATOM   4989 O O      . GLU B 2 323 ? 33.159 13.106  24.609 1.00 5.80  ? 323 GLU A O      1 
ATOM   4990 C CB     . GLU B 2 323 ? 32.441 13.077  27.663 1.00 6.94  ? 323 GLU A CB     1 
ATOM   4991 C CG     . GLU B 2 323 ? 31.923 13.933  28.798 1.00 10.79 ? 323 GLU A CG     1 
ATOM   4992 C CD     . GLU B 2 323 ? 30.751 13.300  29.530 1.00 13.27 ? 323 GLU A CD     1 
ATOM   4993 O OE1    . GLU B 2 323 ? 29.843 12.756  28.860 1.00 14.00 ? 323 GLU A OE1    1 
ATOM   4994 O OE2    . GLU B 2 323 ? 30.734 13.367  30.788 1.00 14.68 ? 323 GLU A OE2    1 
ATOM   4995 H H      . GLU B 2 323 ? 32.205 15.272  26.365 1.00 20.00 ? 323 GLU A H      1 
ATOM   4996 N N      . MET B 2 324 ? 34.730 11.953  25.742 1.00 8.43  ? 324 MET A N      1 
ATOM   4997 C CA     . MET B 2 324 ? 35.042 11.080  24.625 1.00 7.10  ? 324 MET A CA     1 
ATOM   4998 C C      . MET B 2 324 ? 33.778 10.352  24.167 1.00 9.82  ? 324 MET A C      1 
ATOM   4999 O O      . MET B 2 324 ? 33.629 10.013  23.007 1.00 12.65 ? 324 MET A O      1 
ATOM   5000 C CB     . MET B 2 324 ? 36.065 10.067  25.078 1.00 6.22  ? 324 MET A CB     1 
ATOM   5001 C CG     . MET B 2 324 ? 37.398 10.653  25.380 1.00 7.43  ? 324 MET A CG     1 
ATOM   5002 S SD     . MET B 2 324 ? 38.276 10.957  23.867 1.00 13.24 ? 324 MET A SD     1 
ATOM   5003 C CE     . MET B 2 324 ? 37.306 9.879   22.662 1.00 13.29 ? 324 MET A CE     1 
ATOM   5004 H H      . MET B 2 324 ? 35.223 11.854  26.585 1.00 20.00 ? 324 MET A H      1 
ATOM   5005 N N      . ALA B 2 325 ? 32.844 10.140  25.076 1.00 10.50 ? 325 ALA A N      1 
ATOM   5006 C CA     . ALA B 2 325 ? 31.624 9.437   24.732 1.00 12.43 ? 325 ALA A CA     1 
ATOM   5007 C C      . ALA B 2 325 ? 30.950 10.047  23.533 1.00 13.97 ? 325 ALA A C      1 
ATOM   5008 O O      . ALA B 2 325 ? 30.332 9.342   22.752 1.00 17.04 ? 325 ALA A O      1 
ATOM   5009 C CB     . ALA B 2 325 ? 30.688 9.452   25.909 1.00 14.29 ? 325 ALA A CB     1 
ATOM   5010 H H      . ALA B 2 325 ? 32.989 10.442  25.987 1.00 20.00 ? 325 ALA A H      1 
ATOM   5011 N N      . SER B 2 326 ? 31.062 11.363  23.404 1.00 14.35 ? 326 SER A N      1 
ATOM   5012 C CA     . SER B 2 326 ? 30.441 12.078  22.297 1.00 13.57 ? 326 SER A CA     1 
ATOM   5013 C C      . SER B 2 326 ? 31.183 11.826  20.981 1.00 11.62 ? 326 SER A C      1 
ATOM   5014 O O      . SER B 2 326 ? 30.574 11.618  19.936 1.00 8.64  ? 326 SER A O      1 
ATOM   5015 C CB     . SER B 2 326 ? 30.392 13.565  22.607 1.00 14.70 ? 326 SER A CB     1 
ATOM   5016 O OG     . SER B 2 326 ? 29.272 14.161  21.986 1.00 15.18 ? 326 SER A OG     1 
ATOM   5017 H H      . SER B 2 326 ? 31.552 11.857  24.075 1.00 20.00 ? 326 SER A H      1 
ATOM   5018 H HG     . SER B 2 326 ? 29.265 15.101  22.210 1.00 20.00 ? 326 SER A HG     1 
ATOM   5019 N N      . LEU B 2 327 ? 32.505 11.827  21.035 1.00 9.96  ? 327 LEU A N      1 
ATOM   5020 C CA     . LEU B 2 327 ? 33.297 11.581  19.833 1.00 8.11  ? 327 LEU A CA     1 
ATOM   5021 C C      . LEU B 2 327 ? 32.997 10.173  19.405 1.00 10.47 ? 327 LEU A C      1 
ATOM   5022 O O      . LEU B 2 327 ? 32.504 9.944   18.298 1.00 11.47 ? 327 LEU A O      1 
ATOM   5023 C CB     . LEU B 2 327 ? 34.796 11.681  20.114 1.00 4.12  ? 327 LEU A CB     1 
ATOM   5024 C CG     . LEU B 2 327 ? 35.670 12.136  18.950 1.00 2.01  ? 327 LEU A CG     1 
ATOM   5025 C CD1    . LEU B 2 327 ? 37.128 11.838  19.250 1.00 4.49  ? 327 LEU A CD1    1 
ATOM   5026 C CD2    . LEU B 2 327 ? 35.248 11.456  17.668 1.00 2.00  ? 327 LEU A CD2    1 
ATOM   5027 H H      . LEU B 2 327 ? 32.955 11.969  21.896 1.00 20.00 ? 327 LEU A H      1 
ATOM   5028 N N      . GLU B 2 328 ? 33.213 9.250   20.344 1.00 13.04 ? 328 GLU A N      1 
ATOM   5029 C CA     . GLU B 2 328 ? 33.026 7.821   20.116 1.00 13.84 ? 328 GLU A CA     1 
ATOM   5030 C C      . GLU B 2 328 ? 31.640 7.505   19.618 1.00 14.93 ? 328 GLU A C      1 
ATOM   5031 O O      . GLU B 2 328 ? 31.458 6.610   18.810 1.00 15.90 ? 328 GLU A O      1 
ATOM   5032 C CB     . GLU B 2 328 ? 33.338 7.020   21.383 1.00 12.45 ? 328 GLU A CB     1 
ATOM   5033 C CG     . GLU B 2 328 ? 34.804 7.074   21.757 1.00 14.50 ? 328 GLU A CG     1 
ATOM   5034 C CD     . GLU B 2 328 ? 35.158 6.284   23.007 1.00 15.52 ? 328 GLU A CD     1 
ATOM   5035 O OE1    . GLU B 2 328 ? 34.261 5.988   23.844 1.00 16.15 ? 328 GLU A OE1    1 
ATOM   5036 O OE2    . GLU B 2 328 ? 36.368 5.984   23.161 1.00 17.28 ? 328 GLU A OE2    1 
ATOM   5037 H H      . GLU B 2 328 ? 33.547 9.536   21.218 1.00 20.00 ? 328 GLU A H      1 
ATOM   5038 N N      . SER B 2 329 ? 30.660 8.263   20.063 1.00 14.80 ? 329 SER A N      1 
ATOM   5039 C CA     . SER B 2 329 ? 29.322 8.006   19.585 1.00 17.48 ? 329 SER A CA     1 
ATOM   5040 C C      . SER B 2 329 ? 29.289 8.166   18.058 1.00 17.92 ? 329 SER A C      1 
ATOM   5041 O O      . SER B 2 329 ? 28.847 7.262   17.332 1.00 17.55 ? 329 SER A O      1 
ATOM   5042 C CB     . SER B 2 329 ? 28.336 8.973   20.210 1.00 19.44 ? 329 SER A CB     1 
ATOM   5043 O OG     . SER B 2 329 ? 27.113 8.930   19.484 1.00 23.80 ? 329 SER A OG     1 
ATOM   5044 H H      . SER B 2 329 ? 30.837 8.988   20.684 1.00 20.00 ? 329 SER A H      1 
ATOM   5045 H HG     . SER B 2 329 ? 26.487 9.526   19.916 1.00 20.00 ? 329 SER A HG     1 
ATOM   5046 N N      . CYS B 2 330 ? 29.825 9.294   17.583 1.00 14.97 ? 330 CYS A N      1 
ATOM   5047 C CA     . CYS B 2 330 ? 29.832 9.601   16.169 1.00 10.55 ? 330 CYS A CA     1 
ATOM   5048 C C      . CYS B 2 330 ? 30.406 8.505   15.300 1.00 8.28  ? 330 CYS A C      1 
ATOM   5049 O O      . CYS B 2 330 ? 29.743 8.043   14.382 1.00 7.49  ? 330 CYS A O      1 
ATOM   5050 C CB     . CYS B 2 330 ? 30.570 10.908  15.922 1.00 11.10 ? 330 CYS A CB     1 
ATOM   5051 S SG     . CYS B 2 330 ? 29.817 12.283  16.780 1.00 8.42  ? 330 CYS A SG     1 
ATOM   5052 H H      . CYS B 2 330 ? 30.272 9.927   18.204 1.00 20.00 ? 330 CYS A H      1 
ATOM   5053 N N      . ILE B 2 331 ? 31.617 8.061   15.596 1.00 6.20  ? 331 ILE A N      1 
ATOM   5054 C CA     . ILE B 2 331 ? 32.216 7.036   14.754 1.00 9.15  ? 331 ILE A CA     1 
ATOM   5055 C C      . ILE B 2 331 ? 31.471 5.730   14.784 1.00 10.50 ? 331 ILE A C      1 
ATOM   5056 O O      . ILE B 2 331 ? 31.421 5.043   13.764 1.00 10.16 ? 331 ILE A O      1 
ATOM   5057 C CB     . ILE B 2 331 ? 33.690 6.787   15.046 1.00 11.63 ? 331 ILE A CB     1 
ATOM   5058 C CG1    . ILE B 2 331 ? 34.281 5.945   13.922 1.00 11.95 ? 331 ILE A CG1    1 
ATOM   5059 C CG2    . ILE B 2 331 ? 33.865 6.113   16.375 1.00 13.63 ? 331 ILE A CG2    1 
ATOM   5060 C CD1    . ILE B 2 331 ? 34.144 6.571   12.536 1.00 9.28  ? 331 ILE A CD1    1 
ATOM   5061 H H      . ILE B 2 331 ? 32.096 8.394   16.389 1.00 20.00 ? 331 ILE A H      1 
ATOM   5062 N N      . ARG B 2 332 ? 30.873 5.393   15.926 1.00 12.11 ? 332 ARG A N      1 
ATOM   5063 C CA     . ARG B 2 332 ? 30.131 4.148   16.026 1.00 14.21 ? 332 ARG A CA     1 
ATOM   5064 C C      . ARG B 2 332 ? 28.962 4.212   15.070 1.00 18.17 ? 332 ARG A C      1 
ATOM   5065 O O      . ARG B 2 332 ? 28.831 3.377   14.193 1.00 19.36 ? 332 ARG A O      1 
ATOM   5066 C CB     . ARG B 2 332 ? 29.637 3.915   17.437 1.00 11.85 ? 332 ARG A CB     1 
ATOM   5067 C CG     . ARG B 2 332 ? 30.673 3.341   18.368 1.00 10.99 ? 332 ARG A CG     1 
ATOM   5068 C CD     . ARG B 2 332 ? 30.011 2.926   19.650 1.00 11.21 ? 332 ARG A CD     1 
ATOM   5069 N NE     . ARG B 2 332 ? 30.979 2.464   20.625 1.00 11.04 ? 332 ARG A NE     1 
ATOM   5070 C CZ     . ARG B 2 332 ? 31.204 3.058   21.790 1.00 13.87 ? 332 ARG A CZ     1 
ATOM   5071 N NH1    . ARG B 2 332 ? 30.512 4.150   22.135 1.00 13.67 ? 332 ARG A NH1    1 
ATOM   5072 N NH2    . ARG B 2 332 ? 32.114 2.552   22.618 1.00 12.33 ? 332 ARG A NH2    1 
ATOM   5073 H H      . ARG B 2 332 ? 30.980 5.972   16.722 1.00 20.00 ? 332 ARG A H      1 
ATOM   5074 H HE     . ARG B 2 332 ? 31.455 1.668   20.434 1.00 20.00 ? 332 ARG A HE     1 
ATOM   5075 H HH11   . ARG B 2 332 ? 29.809 4.534   21.523 1.00 20.00 ? 332 ARG A HH11   1 
ATOM   5076 H HH12   . ARG B 2 332 ? 30.683 4.614   23.012 1.00 20.00 ? 332 ARG A HH12   1 
ATOM   5077 H HH21   . ARG B 2 332 ? 32.608 1.739   22.374 1.00 20.00 ? 332 ARG A HH21   1 
ATOM   5078 H HH22   . ARG B 2 332 ? 32.281 3.020   23.497 1.00 20.00 ? 332 ARG A HH22   1 
ATOM   5079 N N      . GLU B 2 333 ? 28.155 5.253   15.191 1.00 20.86 ? 333 GLU A N      1 
ATOM   5080 C CA     . GLU B 2 333 ? 27.005 5.432   14.325 1.00 24.13 ? 333 GLU A CA     1 
ATOM   5081 C C      . GLU B 2 333 ? 27.377 5.269   12.850 1.00 24.65 ? 333 GLU A C      1 
ATOM   5082 O O      . GLU B 2 333 ? 26.662 4.597   12.096 1.00 25.07 ? 333 GLU A O      1 
ATOM   5083 C CB     . GLU B 2 333 ? 26.389 6.812   14.577 1.00 29.71 ? 333 GLU A CB     1 
ATOM   5084 C CG     . GLU B 2 333 ? 25.407 7.269   13.521 1.00 36.03 ? 333 GLU A CG     1 
ATOM   5085 C CD     . GLU B 2 333 ? 24.876 8.650   13.792 1.00 40.65 ? 333 GLU A CD     1 
ATOM   5086 O OE1    . GLU B 2 333 ? 23.896 8.743   14.554 1.00 42.54 ? 333 GLU A OE1    1 
ATOM   5087 O OE2    . GLU B 2 333 ? 25.428 9.634   13.241 1.00 42.42 ? 333 GLU A OE2    1 
ATOM   5088 H H      . GLU B 2 333 ? 28.354 5.938   15.872 1.00 20.00 ? 333 GLU A H      1 
ATOM   5089 N N      . ASP B 2 334 ? 28.487 5.876   12.430 1.00 24.41 ? 334 ASP A N      1 
ATOM   5090 C CA     . ASP B 2 334 ? 28.906 5.789   11.031 1.00 23.68 ? 334 ASP A CA     1 
ATOM   5091 C C      . ASP B 2 334 ? 29.207 4.342   10.729 1.00 21.64 ? 334 ASP A C      1 
ATOM   5092 O O      . ASP B 2 334 ? 28.478 3.689   9.975  1.00 21.42 ? 334 ASP A O      1 
ATOM   5093 C CB     . ASP B 2 334 ? 30.157 6.648   10.760 1.00 26.60 ? 334 ASP A CB     1 
ATOM   5094 C CG     . ASP B 2 334 ? 30.482 6.784   9.263  1.00 26.61 ? 334 ASP A CG     1 
ATOM   5095 O OD1    . ASP B 2 334 ? 30.041 5.961   8.433  1.00 27.37 ? 334 ASP A OD1    1 
ATOM   5096 O OD2    . ASP B 2 334 ? 31.196 7.738   8.902  1.00 27.21 ? 334 ASP A OD2    1 
ATOM   5097 H H      . ASP B 2 334 ? 29.047 6.364   13.081 1.00 20.00 ? 334 ASP A H      1 
ATOM   5098 N N      . LEU B 2 335 ? 30.251 3.827   11.363 1.00 19.47 ? 335 LEU A N      1 
ATOM   5099 C CA     . LEU B 2 335 ? 30.666 2.451   11.150 1.00 20.17 ? 335 LEU A CA     1 
ATOM   5100 C C      . LEU B 2 335 ? 29.580 1.381   11.282 1.00 24.17 ? 335 LEU A C      1 
ATOM   5101 O O      . LEU B 2 335 ? 29.518 0.465   10.469 1.00 23.14 ? 335 LEU A O      1 
ATOM   5102 C CB     . LEU B 2 335 ? 31.892 2.147   11.998 1.00 17.41 ? 335 LEU A CB     1 
ATOM   5103 C CG     . LEU B 2 335 ? 33.199 2.319   11.229 1.00 13.65 ? 335 LEU A CG     1 
ATOM   5104 C CD1    . LEU B 2 335 ? 33.029 3.222   10.026 1.00 10.66 ? 335 LEU A CD1    1 
ATOM   5105 C CD2    . LEU B 2 335 ? 34.233 2.858   12.165 1.00 13.45 ? 335 LEU A CD2    1 
ATOM   5106 H H      . LEU B 2 335 ? 30.723 4.366   12.038 1.00 20.00 ? 335 LEU A H      1 
ATOM   5107 N N      . ASN B 2 336 ? 28.696 1.502   12.260 1.00 29.35 ? 336 ASN A N      1 
ATOM   5108 C CA     . ASN B 2 336 ? 27.634 0.510   12.409 1.00 33.29 ? 336 ASN A CA     1 
ATOM   5109 C C      . ASN B 2 336 ? 26.820 0.397   11.119 1.00 33.70 ? 336 ASN A C      1 
ATOM   5110 O O      . ASN B 2 336 ? 26.358 -0.678  10.749 1.00 34.96 ? 336 ASN A O      1 
ATOM   5111 C CB     . ASN B 2 336 ? 26.693 0.876   13.560 1.00 36.93 ? 336 ASN A CB     1 
ATOM   5112 C CG     . ASN B 2 336 ? 25.469 -0.033  13.628 1.00 36.37 ? 336 ASN A CG     1 
ATOM   5113 O OD1    . ASN B 2 336 ? 25.594 -1.254  13.645 1.00 38.50 ? 336 ASN A OD1    1 
ATOM   5114 N ND2    . ASN B 2 336 ? 24.283 0.567   13.673 1.00 40.82 ? 336 ASN A ND2    1 
ATOM   5115 H H      . ASN B 2 336 ? 28.732 2.260   12.843 1.00 20.00 ? 336 ASN A H      1 
ATOM   5116 H HD21   . ASN B 2 336 ? 23.483 0.006   13.730 1.00 20.00 ? 336 ASN A HD21   1 
ATOM   5117 H HD22   . ASN B 2 336 ? 24.236 1.552   13.681 1.00 20.00 ? 336 ASN A HD22   1 
ATOM   5118 N N      . GLU B 2 337 ? 26.656 1.510   10.430 1.00 34.22 ? 337 GLU A N      1 
ATOM   5119 C CA     . GLU B 2 337 ? 25.879 1.522   9.209  1.00 35.67 ? 337 GLU A CA     1 
ATOM   5120 C C      . GLU B 2 337 ? 26.625 1.042   8.000  1.00 33.97 ? 337 GLU A C      1 
ATOM   5121 O O      . GLU B 2 337 ? 26.076 0.335   7.176  1.00 33.74 ? 337 GLU A O      1 
ATOM   5122 C CB     . GLU B 2 337 ? 25.402 2.937   8.919  1.00 40.86 ? 337 GLU A CB     1 
ATOM   5123 C CG     . GLU B 2 337 ? 24.115 3.320   9.590  1.00 44.83 ? 337 GLU A CG     1 
ATOM   5124 C CD     . GLU B 2 337 ? 22.912 2.913   8.781  1.00 46.95 ? 337 GLU A CD     1 
ATOM   5125 O OE1    . GLU B 2 337 ? 22.865 3.219   7.568  1.00 48.32 ? 337 GLU A OE1    1 
ATOM   5126 O OE2    . GLU B 2 337 ? 22.001 2.298   9.365  1.00 48.21 ? 337 GLU A OE2    1 
ATOM   5127 H H      . GLU B 2 337 ? 27.062 2.346   10.763 1.00 20.00 ? 337 GLU A H      1 
ATOM   5128 N N      . ASN B 2 338 ? 27.890 1.406   7.903  1.00 33.82 ? 338 ASN A N      1 
ATOM   5129 C CA     . ASN B 2 338 ? 28.655 1.080   6.718  1.00 31.55 ? 338 ASN A CA     1 
ATOM   5130 C C      . ASN B 2 338 ? 29.699 0.005   6.847  1.00 28.97 ? 338 ASN A C      1 
ATOM   5131 O O      . ASN B 2 338 ? 30.315 -0.364  5.849  1.00 30.05 ? 338 ASN A O      1 
ATOM   5132 C CB     . ASN B 2 338 ? 29.323 2.347   6.200  1.00 34.47 ? 338 ASN A CB     1 
ATOM   5133 C CG     . ASN B 2 338 ? 28.326 3.400   5.780  1.00 36.51 ? 338 ASN A CG     1 
ATOM   5134 O OD1    . ASN B 2 338 ? 28.022 3.534   4.597  1.00 39.25 ? 338 ASN A OD1    1 
ATOM   5135 N ND2    . ASN B 2 338 ? 27.817 4.168   6.743  1.00 36.68 ? 338 ASN A ND2    1 
ATOM   5136 H H      . ASN B 2 338 ? 28.328 1.875   8.654  1.00 20.00 ? 338 ASN A H      1 
ATOM   5137 H HD21   . ASN B 2 338 ? 27.161 4.849   6.483  1.00 20.00 ? 338 ASN A HD21   1 
ATOM   5138 H HD22   . ASN B 2 338 ? 28.102 4.038   7.675  1.00 20.00 ? 338 ASN A HD22   1 
ATOM   5139 N N      . ALA B 2 339 ? 29.944 -0.493  8.051  1.00 24.40 ? 339 ALA A N      1 
ATOM   5140 C CA     . ALA B 2 339 ? 30.982 -1.504  8.181  1.00 20.84 ? 339 ALA A CA     1 
ATOM   5141 C C      . ALA B 2 339 ? 30.548 -2.916  7.934  1.00 20.40 ? 339 ALA A C      1 
ATOM   5142 O O      . ALA B 2 339 ? 29.512 -3.378  8.427  1.00 21.12 ? 339 ALA A O      1 
ATOM   5143 C CB     . ALA B 2 339 ? 31.720 -1.412  9.526  1.00 19.05 ? 339 ALA A CB     1 
ATOM   5144 H H      . ALA B 2 339 ? 29.432 -0.211  8.816  1.00 20.00 ? 339 ALA A H      1 
ATOM   5145 N N      . PRO B 2 340 ? 31.273 -3.587  7.045  1.00 17.14 ? 340 PRO A N      1 
ATOM   5146 C CA     . PRO B 2 340 ? 30.919 -4.966  6.779  1.00 15.05 ? 340 PRO A CA     1 
ATOM   5147 C C      . PRO B 2 340 ? 31.456 -5.711  7.990  1.00 13.67 ? 340 PRO A C      1 
ATOM   5148 O O      . PRO B 2 340 ? 32.569 -5.416  8.478  1.00 9.50  ? 340 PRO A O      1 
ATOM   5149 C CB     . PRO B 2 340 ? 31.745 -5.277  5.543  1.00 13.12 ? 340 PRO A CB     1 
ATOM   5150 C CG     . PRO B 2 340 ? 32.940 -4.440  5.727  1.00 13.59 ? 340 PRO A CG     1 
ATOM   5151 C CD     . PRO B 2 340 ? 32.336 -3.143  6.136  1.00 15.82 ? 340 PRO A CD     1 
ATOM   5152 N N      . ARG B 2 341 ? 30.588 -6.549  8.557  1.00 14.54 ? 341 ARG A N      1 
ATOM   5153 C CA     . ARG B 2 341 ? 30.906 -7.396  9.696  1.00 13.20 ? 341 ARG A CA     1 
ATOM   5154 C C      . ARG B 2 341 ? 31.870 -8.517  9.263  1.00 10.83 ? 341 ARG A C      1 
ATOM   5155 O O      . ARG B 2 341 ? 31.965 -8.854  8.077  1.00 12.31 ? 341 ARG A O      1 
ATOM   5156 C CB     . ARG B 2 341 ? 29.624 -8.015  10.222 1.00 18.31 ? 341 ARG A CB     1 
ATOM   5157 C CG     . ARG B 2 341 ? 29.061 -7.327  11.444 1.00 26.10 ? 341 ARG A CG     1 
ATOM   5158 C CD     . ARG B 2 341 ? 27.954 -6.354  11.139 1.00 30.37 ? 341 ARG A CD     1 
ATOM   5159 N NE     . ARG B 2 341 ? 28.417 -5.039  10.736 1.00 33.30 ? 341 ARG A NE     1 
ATOM   5160 C CZ     . ARG B 2 341 ? 27.882 -3.903  11.178 1.00 32.72 ? 341 ARG A CZ     1 
ATOM   5161 N NH1    . ARG B 2 341 ? 26.903 -3.909  12.084 1.00 36.12 ? 341 ARG A NH1    1 
ATOM   5162 N NH2    . ARG B 2 341 ? 28.357 -2.747  10.738 1.00 33.85 ? 341 ARG A NH2    1 
ATOM   5163 H H      . ARG B 2 341 ? 29.708 -6.626  8.152  1.00 20.00 ? 341 ARG A H      1 
ATOM   5164 H HE     . ARG B 2 341 ? 29.153 -4.976  10.103 1.00 20.00 ? 341 ARG A HE     1 
ATOM   5165 H HH11   . ARG B 2 341 ? 26.565 -4.753  12.471 1.00 20.00 ? 341 ARG A HH11   1 
ATOM   5166 H HH12   . ARG B 2 341 ? 26.533 -3.025  12.421 1.00 20.00 ? 341 ARG A HH12   1 
ATOM   5167 H HH21   . ARG B 2 341 ? 29.114 -2.725  10.093 1.00 20.00 ? 341 ARG A HH21   1 
ATOM   5168 H HH22   . ARG B 2 341 ? 27.976 -1.881  11.074 1.00 20.00 ? 341 ARG A HH22   1 
ATOM   5169 N N      . ALA B 2 342 ? 32.612 -9.064  10.210 1.00 7.14  ? 342 ALA A N      1 
ATOM   5170 C CA     . ALA B 2 342 ? 33.537 -10.148 9.913  1.00 6.94  ? 342 ALA A CA     1 
ATOM   5171 C C      . ALA B 2 342 ? 33.809 -10.801 11.246 1.00 9.12  ? 342 ALA A C      1 
ATOM   5172 O O      . ALA B 2 342 ? 33.118 -10.512 12.230 1.00 9.97  ? 342 ALA A O      1 
ATOM   5173 C CB     . ALA B 2 342 ? 34.815 -9.620  9.309  1.00 5.90  ? 342 ALA A CB     1 
ATOM   5174 H H      . ALA B 2 342 ? 32.539 -8.727  11.130 1.00 20.00 ? 342 ALA A H      1 
ATOM   5175 N N      . MET B 2 343 ? 34.774 -11.707 11.311 1.00 12.08 ? 343 MET A N      1 
ATOM   5176 C CA     . MET B 2 343 ? 35.043 -12.341 12.600 1.00 16.06 ? 343 MET A CA     1 
ATOM   5177 C C      . MET B 2 343 ? 36.501 -12.640 12.889 1.00 19.22 ? 343 MET A C      1 
ATOM   5178 O O      . MET B 2 343 ? 37.275 -13.045 11.999 1.00 19.04 ? 343 MET A O      1 
ATOM   5179 C CB     . MET B 2 343 ? 34.195 -13.613 12.785 1.00 16.75 ? 343 MET A CB     1 
ATOM   5180 C CG     . MET B 2 343 ? 32.683 -13.404 12.574 1.00 15.46 ? 343 MET A CG     1 
ATOM   5181 S SD     . MET B 2 343 ? 31.628 -14.552 13.487 1.00 13.91 ? 343 MET A SD     1 
ATOM   5182 C CE     . MET B 2 343 ? 32.731 -15.936 13.555 1.00 15.82 ? 343 MET A CE     1 
ATOM   5183 H H      . MET B 2 343 ? 35.289 -11.978 10.518 1.00 20.00 ? 343 MET A H      1 
ATOM   5184 N N      . ALA B 2 344 ? 36.867 -12.366 14.138 1.00 22.76 ? 344 ALA A N      1 
ATOM   5185 C CA     . ALA B 2 344 ? 38.226 -12.592 14.632 1.00 22.68 ? 344 ALA A CA     1 
ATOM   5186 C C      . ALA B 2 344 ? 38.168 -12.832 16.134 1.00 22.21 ? 344 ALA A C      1 
ATOM   5187 O O      . ALA B 2 344 ? 37.212 -12.423 16.828 1.00 23.32 ? 344 ALA A O      1 
ATOM   5188 C CB     . ALA B 2 344 ? 39.124 -11.410 14.317 1.00 23.74 ? 344 ALA A CB     1 
ATOM   5189 H H      . ALA B 2 344 ? 36.196 -12.007 14.768 1.00 20.00 ? 344 ALA A H      1 
ATOM   5190 N N      . VAL B 2 345 ? 39.159 -13.554 16.624 1.00 21.09 ? 345 VAL A N      1 
ATOM   5191 C CA     . VAL B 2 345 ? 39.256 -13.887 18.018 1.00 19.42 ? 345 VAL A CA     1 
ATOM   5192 C C      . VAL B 2 345 ? 40.537 -13.286 18.520 1.00 20.16 ? 345 VAL A C      1 
ATOM   5193 O O      . VAL B 2 345 ? 41.619 -13.549 17.985 1.00 20.54 ? 345 VAL A O      1 
ATOM   5194 C CB     . VAL B 2 345 ? 39.200 -15.414 18.208 1.00 18.37 ? 345 VAL A CB     1 
ATOM   5195 C CG1    . VAL B 2 345 ? 39.604 -15.820 19.644 1.00 18.57 ? 345 VAL A CG1    1 
ATOM   5196 C CG2    . VAL B 2 345 ? 37.774 -15.890 17.874 1.00 16.49 ? 345 VAL A CG2    1 
ATOM   5197 H H      . VAL B 2 345 ? 39.811 -13.899 16.054 1.00 20.00 ? 345 VAL A H      1 
ATOM   5198 N N      . ILE B 2 346 ? 40.400 -12.455 19.544 1.00 19.96 ? 346 ILE A N      1 
ATOM   5199 C CA     . ILE B 2 346 ? 41.535 -11.753 20.126 1.00 19.84 ? 346 ILE A CA     1 
ATOM   5200 C C      . ILE B 2 346 ? 42.290 -12.612 21.157 1.00 25.01 ? 346 ILE A C      1 
ATOM   5201 O O      . ILE B 2 346 ? 43.512 -12.762 21.087 1.00 26.27 ? 346 ILE A O      1 
ATOM   5202 C CB     . ILE B 2 346 ? 41.064 -10.374 20.720 1.00 14.91 ? 346 ILE A CB     1 
ATOM   5203 C CG1    . ILE B 2 346 ? 40.197 -9.637  19.691 1.00 13.86 ? 346 ILE A CG1    1 
ATOM   5204 C CG2    . ILE B 2 346 ? 42.240 -9.502  21.074 1.00 12.12 ? 346 ILE A CG2    1 
ATOM   5205 C CD1    . ILE B 2 346 ? 40.035 -8.155  19.909 1.00 11.68 ? 346 ILE A CD1    1 
ATOM   5206 H H      . ILE B 2 346 ? 39.522 -12.295 19.884 1.00 20.00 ? 346 ILE A H      1 
ATOM   5207 N N      . ASP B 2 347 ? 41.563 -13.169 22.117 1.00 30.98 ? 347 ASP A N      1 
ATOM   5208 C CA     . ASP B 2 347 ? 42.176 -14.016 23.138 1.00 36.74 ? 347 ASP A CA     1 
ATOM   5209 C C      . ASP B 2 347 ? 41.686 -15.422 22.783 1.00 35.90 ? 347 ASP A C      1 
ATOM   5210 O O      . ASP B 2 347 ? 40.537 -15.775 23.056 1.00 39.42 ? 347 ASP A O      1 
ATOM   5211 C CB     . ASP B 2 347 ? 41.701 -13.573 24.524 1.00 42.66 ? 347 ASP A CB     1 
ATOM   5212 C CG     . ASP B 2 347 ? 42.674 -13.960 25.627 1.00 47.13 ? 347 ASP A CG     1 
ATOM   5213 O OD1    . ASP B 2 347 ? 43.903 -13.894 25.397 1.00 50.55 ? 347 ASP A OD1    1 
ATOM   5214 O OD2    . ASP B 2 347 ? 42.215 -14.320 26.734 1.00 49.56 ? 347 ASP A OD2    1 
ATOM   5215 H H      . ASP B 2 347 ? 40.601 -13.006 22.120 1.00 20.00 ? 347 ASP A H      1 
ATOM   5216 N N      . PRO B 2 348 ? 42.569 -16.261 22.226 1.00 32.98 ? 348 PRO A N      1 
ATOM   5217 C CA     . PRO B 2 348 ? 42.043 -17.588 21.881 1.00 32.22 ? 348 PRO A CA     1 
ATOM   5218 C C      . PRO B 2 348 ? 42.414 -18.872 22.641 1.00 30.50 ? 348 PRO A C      1 
ATOM   5219 O O      . PRO B 2 348 ? 43.596 -19.166 22.910 1.00 29.54 ? 348 PRO A O      1 
ATOM   5220 C CB     . PRO B 2 348 ? 42.431 -17.711 20.404 1.00 33.20 ? 348 PRO A CB     1 
ATOM   5221 C CG     . PRO B 2 348 ? 43.756 -16.995 20.356 1.00 34.03 ? 348 PRO A CG     1 
ATOM   5222 C CD     . PRO B 2 348 ? 43.476 -15.757 21.183 1.00 32.50 ? 348 PRO A CD     1 
ATOM   5223 N N      . VAL B 2 349 ? 41.367 -19.653 22.915 1.00 28.41 ? 349 VAL A N      1 
ATOM   5224 C CA     . VAL B 2 349 ? 41.484 -20.965 23.538 1.00 27.18 ? 349 VAL A CA     1 
ATOM   5225 C C      . VAL B 2 349 ? 40.808 -21.919 22.540 1.00 27.55 ? 349 VAL A C      1 
ATOM   5226 O O      . VAL B 2 349 ? 39.704 -21.636 22.037 1.00 25.33 ? 349 VAL A O      1 
ATOM   5227 C CB     . VAL B 2 349 ? 40.781 -21.062 24.912 1.00 27.82 ? 349 VAL A CB     1 
ATOM   5228 C CG1    . VAL B 2 349 ? 39.277 -20.774 24.797 1.00 26.96 ? 349 VAL A CG1    1 
ATOM   5229 C CG2    . VAL B 2 349 ? 40.997 -22.446 25.489 1.00 28.59 ? 349 VAL A CG2    1 
ATOM   5230 H H      . VAL B 2 349 ? 40.460 -19.334 22.675 1.00 20.00 ? 349 VAL A H      1 
ATOM   5231 N N      . LYS B 2 350 ? 41.503 -23.002 22.192 1.00 28.23 ? 350 LYS A N      1 
ATOM   5232 C CA     . LYS B 2 350 ? 40.995 -23.992 21.236 1.00 26.47 ? 350 LYS A CA     1 
ATOM   5233 C C      . LYS B 2 350 ? 39.721 -24.730 21.654 1.00 26.95 ? 350 LYS A C      1 
ATOM   5234 O O      . LYS B 2 350 ? 39.528 -25.058 22.820 1.00 29.89 ? 350 LYS A O      1 
ATOM   5235 C CB     . LYS B 2 350 ? 42.089 -24.992 20.896 1.00 24.25 ? 350 LYS A CB     1 
ATOM   5236 C CG     . LYS B 2 350 ? 41.647 -26.099 19.991 1.00 24.41 ? 350 LYS A CG     1 
ATOM   5237 C CD     . LYS B 2 350 ? 42.775 -26.470 19.044 1.00 26.36 ? 350 LYS A CD     1 
ATOM   5238 C CE     . LYS B 2 350 ? 42.884 -25.488 17.888 1.00 25.37 ? 350 LYS A CE     1 
ATOM   5239 N NZ     . LYS B 2 350 ? 44.002 -25.847 16.969 1.00 24.36 ? 350 LYS A NZ     1 
ATOM   5240 H H      . LYS B 2 350 ? 42.374 -23.149 22.604 1.00 20.00 ? 350 LYS A H      1 
ATOM   5241 H HZ1    . LYS B 2 350 ? 43.991 -26.841 16.764 1.00 20.00 ? 350 LYS A HZ1    1 
ATOM   5242 H HZ2    . LYS B 2 350 ? 43.894 -25.285 16.084 1.00 20.00 ? 350 LYS A HZ2    1 
ATOM   5243 H HZ3    . LYS B 2 350 ? 44.904 -25.558 17.415 1.00 20.00 ? 350 LYS A HZ3    1 
ATOM   5244 N N      . LEU B 2 351 ? 38.859 -25.018 20.696 1.00 26.78 ? 351 LEU A N      1 
ATOM   5245 C CA     . LEU B 2 351 ? 37.622 -25.714 20.996 1.00 28.80 ? 351 LEU A CA     1 
ATOM   5246 C C      . LEU B 2 351 ? 37.368 -26.733 19.900 1.00 33.35 ? 351 LEU A C      1 
ATOM   5247 O O      . LEU B 2 351 ? 37.159 -26.355 18.743 1.00 32.04 ? 351 LEU A O      1 
ATOM   5248 C CB     . LEU B 2 351 ? 36.465 -24.712 21.073 1.00 25.19 ? 351 LEU A CB     1 
ATOM   5249 C CG     . LEU B 2 351 ? 35.042 -25.222 21.301 1.00 21.56 ? 351 LEU A CG     1 
ATOM   5250 C CD1    . LEU B 2 351 ? 34.191 -24.102 21.845 1.00 20.75 ? 351 LEU A CD1    1 
ATOM   5251 C CD2    . LEU B 2 351 ? 34.441 -25.778 20.046 1.00 20.15 ? 351 LEU A CD2    1 
ATOM   5252 H H      . LEU B 2 351 ? 39.047 -24.765 19.768 1.00 20.00 ? 351 LEU A H      1 
ATOM   5253 N N      . VAL B 2 352 ? 37.441 -28.019 20.244 1.00 37.78 ? 352 VAL A N      1 
ATOM   5254 C CA     . VAL B 2 352 ? 37.177 -29.065 19.264 1.00 41.34 ? 352 VAL A CA     1 
ATOM   5255 C C      . VAL B 2 352 ? 35.811 -29.689 19.474 1.00 44.09 ? 352 VAL A C      1 
ATOM   5256 O O      . VAL B 2 352 ? 35.323 -29.795 20.603 1.00 45.28 ? 352 VAL A O      1 
ATOM   5257 C CB     . VAL B 2 352 ? 38.218 -30.214 19.283 1.00 40.05 ? 352 VAL A CB     1 
ATOM   5258 C CG1    . VAL B 2 352 ? 39.618 -29.670 19.159 1.00 41.06 ? 352 VAL A CG1    1 
ATOM   5259 C CG2    . VAL B 2 352 ? 38.066 -31.046 20.515 1.00 37.36 ? 352 VAL A CG2    1 
ATOM   5260 H H      . VAL B 2 352 ? 37.653 -28.268 21.167 1.00 20.00 ? 352 VAL A H      1 
ATOM   5261 N N      . ILE B 2 353 ? 35.188 -30.066 18.367 1.00 46.52 ? 353 ILE A N      1 
ATOM   5262 C CA     . ILE B 2 353 ? 33.906 -30.737 18.398 1.00 49.60 ? 353 ILE A CA     1 
ATOM   5263 C C      . ILE B 2 353 ? 34.304 -32.136 17.966 1.00 50.43 ? 353 ILE A C      1 
ATOM   5264 O O      . ILE B 2 353 ? 34.869 -32.319 16.878 1.00 48.51 ? 353 ILE A O      1 
ATOM   5265 C CB     . ILE B 2 353 ? 32.913 -30.162 17.375 1.00 52.02 ? 353 ILE A CB     1 
ATOM   5266 C CG1    . ILE B 2 353 ? 32.832 -28.637 17.516 1.00 56.08 ? 353 ILE A CG1    1 
ATOM   5267 C CG2    . ILE B 2 353 ? 31.537 -30.800 17.584 1.00 51.41 ? 353 ILE A CG2    1 
ATOM   5268 C CD1    . ILE B 2 353 ? 32.065 -27.941 16.389 1.00 53.68 ? 353 ILE A CD1    1 
ATOM   5269 H H      . ILE B 2 353 ? 35.605 -29.907 17.502 1.00 20.00 ? 353 ILE A H      1 
ATOM   5270 N N      . GLU B 2 354 ? 34.121 -33.095 18.870 1.00 48.40 ? 354 GLU A N      1 
ATOM   5271 C CA     . GLU B 2 354 ? 34.448 -34.493 18.591 1.00 47.59 ? 354 GLU A CA     1 
ATOM   5272 C C      . GLU B 2 354 ? 33.355 -35.076 17.670 1.00 46.10 ? 354 GLU A C      1 
ATOM   5273 O O      . GLU B 2 354 ? 33.636 -35.742 16.663 1.00 43.74 ? 354 GLU A O      1 
ATOM   5274 C CB     . GLU B 2 354 ? 34.557 -35.258 19.920 1.00 49.13 ? 354 GLU A CB     1 
ATOM   5275 C CG     . GLU B 2 354 ? 35.650 -34.694 20.854 1.00 48.70 ? 354 GLU A CG     1 
ATOM   5276 C CD     . GLU B 2 354 ? 35.542 -35.165 22.305 1.00 48.95 ? 354 GLU A CD     1 
ATOM   5277 O OE1    . GLU B 2 354 ? 34.412 -35.266 22.835 1.00 47.91 ? 354 GLU A OE1    1 
ATOM   5278 O OE2    . GLU B 2 354 ? 36.593 -35.410 22.936 1.00 48.71 ? 354 GLU A OE2    1 
ATOM   5279 H H      . GLU B 2 354 ? 33.757 -32.849 19.746 1.00 20.00 ? 354 GLU A H      1 
ATOM   5280 N N      . ASN B 2 355 ? 32.112 -34.720 17.980 1.00 44.72 ? 355 ASN A N      1 
ATOM   5281 C CA     . ASN B 2 355 ? 30.944 -35.154 17.230 1.00 42.50 ? 355 ASN A CA     1 
ATOM   5282 C C      . ASN B 2 355 ? 31.062 -34.877 15.716 1.00 41.51 ? 355 ASN A C      1 
ATOM   5283 O O      . ASN B 2 355 ? 30.452 -35.568 14.897 1.00 41.25 ? 355 ASN A O      1 
ATOM   5284 C CB     . ASN B 2 355 ? 29.722 -34.437 17.824 1.00 43.59 ? 355 ASN A CB     1 
ATOM   5285 C CG     . ASN B 2 355 ? 28.418 -34.785 17.111 1.00 45.96 ? 355 ASN A CG     1 
ATOM   5286 O OD1    . ASN B 2 355 ? 28.230 -34.437 15.938 1.00 45.21 ? 355 ASN A OD1    1 
ATOM   5287 N ND2    . ASN B 2 355 ? 27.492 -35.422 17.827 1.00 46.26 ? 355 ASN A ND2    1 
ATOM   5288 H H      . ASN B 2 355 ? 31.984 -34.096 18.721 1.00 20.00 ? 355 ASN A H      1 
ATOM   5289 H HD21   . ASN B 2 355 ? 26.666 -35.628 17.358 1.00 20.00 ? 355 ASN A HD21   1 
ATOM   5290 H HD22   . ASN B 2 355 ? 27.680 -35.632 18.751 1.00 20.00 ? 355 ASN A HD22   1 
ATOM   5291 N N      . TYR B 2 356 ? 31.870 -33.883 15.353 1.00 42.25 ? 356 TYR A N      1 
ATOM   5292 C CA     . TYR B 2 356 ? 32.056 -33.482 13.958 1.00 42.27 ? 356 TYR A CA     1 
ATOM   5293 C C      . TYR B 2 356 ? 32.796 -34.488 13.069 1.00 44.89 ? 356 TYR A C      1 
ATOM   5294 O O      . TYR B 2 356 ? 33.931 -34.875 13.360 1.00 42.74 ? 356 TYR A O      1 
ATOM   5295 C CB     . TYR B 2 356 ? 32.777 -32.119 13.888 1.00 40.55 ? 356 TYR A CB     1 
ATOM   5296 C CG     . TYR B 2 356 ? 32.705 -31.443 12.528 1.00 37.70 ? 356 TYR A CG     1 
ATOM   5297 C CD1    . TYR B 2 356 ? 31.507 -30.889 12.077 1.00 36.81 ? 356 TYR A CD1    1 
ATOM   5298 C CD2    . TYR B 2 356 ? 33.824 -31.367 11.691 1.00 37.15 ? 356 TYR A CD2    1 
ATOM   5299 C CE1    . TYR B 2 356 ? 31.419 -30.283 10.830 1.00 37.15 ? 356 TYR A CE1    1 
ATOM   5300 C CE2    . TYR B 2 356 ? 33.745 -30.762 10.441 1.00 37.24 ? 356 TYR A CE2    1 
ATOM   5301 C CZ     . TYR B 2 356 ? 32.545 -30.221 10.012 1.00 36.30 ? 356 TYR A CZ     1 
ATOM   5302 O OH     . TYR B 2 356 ? 32.461 -29.621 8.766  1.00 34.47 ? 356 TYR A OH     1 
ATOM   5303 H H      . TYR B 2 356 ? 32.385 -33.423 16.031 1.00 20.00 ? 356 TYR A H      1 
ATOM   5304 H HH     . TYR B 2 356 ? 31.527 -29.311 8.658  1.00 20.00 ? 356 TYR A HH     1 
ATOM   5305 N N      . GLN B 2 357 ? 32.144 -34.886 11.974 1.00 48.20 ? 357 GLN A N      1 
ATOM   5306 C CA     . GLN B 2 357 ? 32.731 -35.816 11.001 1.00 50.51 ? 357 GLN A CA     1 
ATOM   5307 C C      . GLN B 2 357 ? 32.888 -35.047 9.692  1.00 49.40 ? 357 GLN A C      1 
ATOM   5308 O O      . GLN B 2 357 ? 31.901 -34.537 9.145  1.00 49.16 ? 357 GLN A O      1 
ATOM   5309 C CB     . GLN B 2 357 ? 31.829 -37.036 10.747 1.00 54.50 ? 357 GLN A CB     1 
ATOM   5310 C CG     . GLN B 2 357 ? 30.915 -37.426 11.899 1.00 56.45 ? 357 GLN A CG     1 
ATOM   5311 C CD     . GLN B 2 357 ? 29.456 -37.120 11.599 1.00 56.64 ? 357 GLN A CD     1 
ATOM   5312 O OE1    . GLN B 2 357 ? 28.870 -37.685 10.673 1.00 55.52 ? 357 GLN A OE1    1 
ATOM   5313 N NE2    . GLN B 2 357 ? 28.869 -36.221 12.373 1.00 57.44 ? 357 GLN A NE2    1 
ATOM   5314 H H      . GLN B 2 357 ? 31.240 -34.544 11.806 1.00 20.00 ? 357 GLN A H      1 
ATOM   5315 H HE21   . GLN B 2 357 ? 27.927 -36.024 12.177 1.00 20.00 ? 357 GLN A HE21   1 
ATOM   5316 H HE22   . GLN B 2 357 ? 29.367 -35.800 13.101 1.00 20.00 ? 357 GLN A HE22   1 
ATOM   5317 N N      . GLY B 2 358 ? 34.116 -34.970 9.191  1.00 47.86 ? 358 GLY A N      1 
ATOM   5318 C CA     . GLY B 2 358 ? 34.364 -34.262 7.947  1.00 47.42 ? 358 GLY A CA     1 
ATOM   5319 C C      . GLY B 2 358 ? 35.608 -33.391 7.998  1.00 45.62 ? 358 GLY A C      1 
ATOM   5320 O O      . GLY B 2 358 ? 36.122 -33.079 9.071  1.00 44.23 ? 358 GLY A O      1 
ATOM   5321 H H      . GLY B 2 358 ? 34.865 -35.383 9.667  1.00 20.00 ? 358 GLY A H      1 
ATOM   5322 N N      . GLU B 2 359 ? 36.113 -33.016 6.829  1.00 48.15 ? 359 GLU A N      1 
ATOM   5323 C CA     . GLU B 2 359 ? 37.303 -32.181 6.733  1.00 46.66 ? 359 GLU A CA     1 
ATOM   5324 C C      . GLU B 2 359 ? 36.969 -30.696 6.844  1.00 41.48 ? 359 GLU A C      1 
ATOM   5325 O O      . GLU B 2 359 ? 37.854 -29.840 6.751  1.00 40.17 ? 359 GLU A O      1 
ATOM   5326 C CB     . GLU B 2 359 ? 38.002 -32.448 5.403  1.00 50.54 ? 359 GLU A CB     1 
ATOM   5327 C CG     . GLU B 2 359 ? 38.884 -33.674 5.383  1.00 55.31 ? 359 GLU A CG     1 
ATOM   5328 C CD     . GLU B 2 359 ? 40.265 -33.404 5.988  1.00 53.30 ? 359 GLU A CD     1 
ATOM   5329 O OE1    . GLU B 2 359 ? 40.327 -32.782 7.083  1.00 54.69 ? 359 GLU A OE1    1 
ATOM   5330 O OE2    . GLU B 2 359 ? 41.281 -33.809 5.363  1.00 53.48 ? 359 GLU A OE2    1 
ATOM   5331 H H      . GLU B 2 359 ? 35.662 -33.290 6.003  1.00 20.00 ? 359 GLU A H      1 
ATOM   5332 N N      . GLY B 2 360 ? 35.687 -30.394 7.013  1.00 38.98 ? 360 GLY A N      1 
ATOM   5333 C CA     . GLY B 2 360 ? 35.277 -29.011 7.127  1.00 36.02 ? 360 GLY A CA     1 
ATOM   5334 C C      . GLY B 2 360 ? 34.378 -28.521 6.000  1.00 35.27 ? 360 GLY A C      1 
ATOM   5335 O O      . GLY B 2 360 ? 34.706 -28.619 4.808  1.00 35.45 ? 360 GLY A O      1 
ATOM   5336 H H      . GLY B 2 360 ? 35.015 -31.094 7.012  1.00 20.00 ? 360 GLY A H      1 
ATOM   5337 N N      . GLU B 2 361 ? 33.241 -27.965 6.391  1.00 33.83 ? 361 GLU A N      1 
ATOM   5338 C CA     . GLU B 2 361 ? 32.279 -27.460 5.434  1.00 34.15 ? 361 GLU A CA     1 
ATOM   5339 C C      . GLU B 2 361 ? 32.439 -25.959 5.182  1.00 37.24 ? 361 GLU A C      1 
ATOM   5340 O O      . GLU B 2 361 ? 33.531 -25.386 5.364  1.00 39.83 ? 361 GLU A O      1 
ATOM   5341 C CB     . GLU B 2 361 ? 30.868 -27.787 5.899  1.00 31.38 ? 361 GLU A CB     1 
ATOM   5342 C CG     . GLU B 2 361 ? 30.643 -27.374 7.314  1.00 30.78 ? 361 GLU A CG     1 
ATOM   5343 C CD     . GLU B 2 361 ? 29.325 -27.808 7.830  1.00 27.39 ? 361 GLU A CD     1 
ATOM   5344 O OE1    . GLU B 2 361 ? 28.301 -27.456 7.201  1.00 28.43 ? 361 GLU A OE1    1 
ATOM   5345 O OE2    . GLU B 2 361 ? 29.326 -28.481 8.881  1.00 28.15 ? 361 GLU A OE2    1 
ATOM   5346 H H      . GLU B 2 361 ? 33.058 -27.916 7.341  1.00 20.00 ? 361 GLU A H      1 
ATOM   5347 N N      . MET B 2 362 ? 31.343 -25.317 4.792  1.00 38.04 ? 362 MET A N      1 
ATOM   5348 C CA     . MET B 2 362 ? 31.364 -23.903 4.485  1.00 36.84 ? 362 MET A CA     1 
ATOM   5349 C C      . MET B 2 362 ? 30.021 -23.309 4.864  1.00 36.91 ? 362 MET A C      1 
ATOM   5350 O O      . MET B 2 362 ? 28.971 -23.808 4.442  1.00 39.31 ? 362 MET A O      1 
ATOM   5351 C CB     . MET B 2 362 ? 31.608 -23.705 2.990  1.00 37.79 ? 362 MET A CB     1 
ATOM   5352 C CG     . MET B 2 362 ? 32.508 -22.547 2.648  1.00 42.01 ? 362 MET A CG     1 
ATOM   5353 S SD     . MET B 2 362 ? 34.198 -23.050 2.298  1.00 47.50 ? 362 MET A SD     1 
ATOM   5354 C CE     . MET B 2 362 ? 34.193 -23.050 0.416  1.00 47.04 ? 362 MET A CE     1 
ATOM   5355 H H      . MET B 2 362 ? 30.492 -25.786 4.685  1.00 20.00 ? 362 MET A H      1 
ATOM   5356 N N      . VAL B 2 363 ? 30.056 -22.262 5.684  1.00 36.99 ? 363 VAL A N      1 
ATOM   5357 C CA     . VAL B 2 363 ? 28.846 -21.580 6.116  1.00 35.53 ? 363 VAL A CA     1 
ATOM   5358 C C      . VAL B 2 363 ? 28.772 -20.194 5.483  1.00 34.18 ? 363 VAL A C      1 
ATOM   5359 O O      . VAL B 2 363 ? 29.768 -19.470 5.436  1.00 33.95 ? 363 VAL A O      1 
ATOM   5360 C CB     . VAL B 2 363 ? 28.792 -21.413 7.641  1.00 34.34 ? 363 VAL A CB     1 
ATOM   5361 C CG1    . VAL B 2 363 ? 27.383 -21.047 8.058  1.00 33.39 ? 363 VAL A CG1    1 
ATOM   5362 C CG2    . VAL B 2 363 ? 29.231 -22.685 8.339  1.00 34.97 ? 363 VAL A CG2    1 
ATOM   5363 H H      . VAL B 2 363 ? 30.909 -21.968 6.046  1.00 20.00 ? 363 VAL A H      1 
ATOM   5364 N N      . THR B 2 364 ? 27.592 -19.848 4.970  1.00 33.09 ? 364 THR A N      1 
ATOM   5365 C CA     . THR B 2 364 ? 27.373 -18.557 4.335  1.00 29.99 ? 364 THR A CA     1 
ATOM   5366 C C      . THR B 2 364 ? 26.975 -17.545 5.368  1.00 26.27 ? 364 THR A C      1 
ATOM   5367 O O      . THR B 2 364 ? 25.920 -17.666 5.993  1.00 27.34 ? 364 THR A O      1 
ATOM   5368 C CB     . THR B 2 364 ? 26.265 -18.621 3.279  1.00 29.72 ? 364 THR A CB     1 
ATOM   5369 O OG1    . THR B 2 364 ? 26.767 -19.294 2.113  1.00 30.13 ? 364 THR A OG1    1 
ATOM   5370 C CG2    . THR B 2 364 ? 25.776 -17.209 2.903  1.00 31.69 ? 364 THR A CG2    1 
ATOM   5371 H H      . THR B 2 364 ? 26.826 -20.450 5.065  1.00 20.00 ? 364 THR A H      1 
ATOM   5372 H HG1    . THR B 2 364 ? 26.102 -19.293 1.422  1.00 20.00 ? 364 THR A HG1    1 
ATOM   5373 N N      . MET B 2 365 ? 27.814 -16.533 5.523  1.00 22.11 ? 365 MET A N      1 
ATOM   5374 C CA     . MET B 2 365 ? 27.558 -15.470 6.479  1.00 20.02 ? 365 MET A CA     1 
ATOM   5375 C C      . MET B 2 365 ? 27.296 -14.142 5.767  1.00 21.95 ? 365 MET A C      1 
ATOM   5376 O O      . MET B 2 365 ? 27.809 -13.893 4.658  1.00 21.33 ? 365 MET A O      1 
ATOM   5377 C CB     . MET B 2 365 ? 28.732 -15.336 7.457  1.00 16.27 ? 365 MET A CB     1 
ATOM   5378 C CG     . MET B 2 365 ? 28.972 -16.583 8.294  1.00 11.82 ? 365 MET A CG     1 
ATOM   5379 S SD     . MET B 2 365 ? 29.581 -16.231 9.929  1.00 14.50 ? 365 MET A SD     1 
ATOM   5380 C CE     . MET B 2 365 ? 31.168 -16.953 9.841  1.00 13.24 ? 365 MET A CE     1 
ATOM   5381 H H      . MET B 2 365 ? 28.617 -16.491 4.964  1.00 20.00 ? 365 MET A H      1 
ATOM   5382 N N      . PRO B 2 366 ? 26.469 -13.284 6.389  1.00 24.59 ? 366 PRO A N      1 
ATOM   5383 C CA     . PRO B 2 366 ? 26.121 -11.975 5.838  1.00 25.71 ? 366 PRO A CA     1 
ATOM   5384 C C      . PRO B 2 366 ? 27.258 -11.005 6.106  1.00 27.86 ? 366 PRO A C      1 
ATOM   5385 O O      . PRO B 2 366 ? 27.960 -11.134 7.117  1.00 26.55 ? 366 PRO A O      1 
ATOM   5386 C CB     . PRO B 2 366 ? 24.909 -11.562 6.678  1.00 25.16 ? 366 PRO A CB     1 
ATOM   5387 C CG     . PRO B 2 366 ? 24.375 -12.823 7.186  1.00 23.03 ? 366 PRO A CG     1 
ATOM   5388 C CD     . PRO B 2 366 ? 25.614 -13.578 7.546  1.00 23.81 ? 366 PRO A CD     1 
ATOM   5389 N N      . ASN B 2 367 ? 27.434 -10.046 5.201  1.00 30.27 ? 367 ASN A N      1 
ATOM   5390 C CA     . ASN B 2 367 ? 28.448 -9.016  5.374  1.00 32.96 ? 367 ASN A CA     1 
ATOM   5391 C C      . ASN B 2 367 ? 27.825 -7.933  6.240  1.00 32.27 ? 367 ASN A C      1 
ATOM   5392 O O      . ASN B 2 367 ? 28.516 -7.032  6.715  1.00 32.00 ? 367 ASN A O      1 
ATOM   5393 C CB     . ASN B 2 367 ? 28.875 -8.451  4.028  1.00 34.72 ? 367 ASN A CB     1 
ATOM   5394 C CG     . ASN B 2 367 ? 29.754 -9.399  3.268  1.00 37.65 ? 367 ASN A CG     1 
ATOM   5395 O OD1    . ASN B 2 367 ? 30.709 -9.952  3.822  1.00 39.08 ? 367 ASN A OD1    1 
ATOM   5396 N ND2    . ASN B 2 367 ? 29.435 -9.613  1.989  1.00 40.61 ? 367 ASN A ND2    1 
ATOM   5397 H H      . ASN B 2 367 ? 26.862 -10.016 4.400  1.00 20.00 ? 367 ASN A H      1 
ATOM   5398 H HD21   . ASN B 2 367 ? 29.997 -10.210 1.480  1.00 20.00 ? 367 ASN A HD21   1 
ATOM   5399 H HD22   . ASN B 2 367 ? 28.651 -9.136  1.612  1.00 20.00 ? 367 ASN A HD22   1 
ATOM   5400 N N      . HIS B 2 368 ? 26.506 -8.015  6.419  1.00 29.74 ? 368 HIS A N      1 
ATOM   5401 C CA     . HIS B 2 368 ? 25.799 -7.058  7.244  1.00 28.78 ? 368 HIS A CA     1 
ATOM   5402 C C      . HIS B 2 368 ? 24.435 -7.557  7.671  1.00 29.85 ? 368 HIS A C      1 
ATOM   5403 O O      . HIS B 2 368 ? 23.457 -7.396  6.947  1.00 31.06 ? 368 HIS A O      1 
ATOM   5404 C CB     . HIS B 2 368 ? 25.643 -5.716  6.528  1.00 25.96 ? 368 HIS A CB     1 
ATOM   5405 C CG     . HIS B 2 368 ? 25.381 -4.575  7.463  1.00 24.43 ? 368 HIS A CG     1 
ATOM   5406 N ND1    . HIS B 2 368 ? 26.219 -3.483  7.561  1.00 21.56 ? 368 HIS A ND1    1 
ATOM   5407 C CD2    . HIS B 2 368 ? 24.370 -4.352  8.337  1.00 23.98 ? 368 HIS A CD2    1 
ATOM   5408 C CE1    . HIS B 2 368 ? 25.731 -2.637  8.450  1.00 23.58 ? 368 HIS A CE1    1 
ATOM   5409 N NE2    . HIS B 2 368 ? 24.607 -3.143  8.935  1.00 25.18 ? 368 HIS A NE2    1 
ATOM   5410 H H      . HIS B 2 368 ? 26.000 -8.712  5.954  1.00 20.00 ? 368 HIS A H      1 
ATOM   5411 H HD1    . HIS B 2 368 ? 27.052 -3.321  7.052  1.00 20.00 ? 368 HIS A HD1    1 
ATOM   5412 H HE2    . HIS B 2 368 ? 24.053 -2.704  9.622  1.00 20.00 ? 368 HIS A HE2    1 
ATOM   5413 N N      . PRO B 2 369 ? 24.341 -8.085  8.905  1.00 31.11 ? 369 PRO A N      1 
ATOM   5414 C CA     . PRO B 2 369 ? 23.157 -8.634  9.566  1.00 32.76 ? 369 PRO A CA     1 
ATOM   5415 C C      . PRO B 2 369 ? 21.890 -7.812  9.489  1.00 35.74 ? 369 PRO A C      1 
ATOM   5416 O O      . PRO B 2 369 ? 20.828 -8.317  9.819  1.00 39.61 ? 369 PRO A O      1 
ATOM   5417 C CB     . PRO B 2 369 ? 23.619 -8.776  11.011 1.00 29.51 ? 369 PRO A CB     1 
ATOM   5418 C CG     . PRO B 2 369 ? 25.010 -9.221  10.843 1.00 31.55 ? 369 PRO A CG     1 
ATOM   5419 C CD     . PRO B 2 369 ? 25.529 -8.279  9.756  1.00 32.73 ? 369 PRO A CD     1 
ATOM   5420 N N      . ASN B 2 370 ? 21.968 -6.548  9.103  1.00 41.68 ? 370 ASN A N      1 
ATOM   5421 C CA     . ASN B 2 370 ? 20.751 -5.762  9.006  1.00 48.14 ? 370 ASN A CA     1 
ATOM   5422 C C      . ASN B 2 370 ? 20.619 -5.113  7.647  1.00 45.42 ? 370 ASN A C      1 
ATOM   5423 O O      . ASN B 2 370 ? 19.652 -4.388  7.385  1.00 46.51 ? 370 ASN A O      1 
ATOM   5424 C CB     . ASN B 2 370 ? 20.687 -4.693  10.095 1.00 57.23 ? 370 ASN A CB     1 
ATOM   5425 C CG     . ASN B 2 370 ? 20.365 -5.266  11.473 1.00 61.27 ? 370 ASN A CG     1 
ATOM   5426 O OD1    . ASN B 2 370 ? 20.542 -6.457  11.720 1.00 61.95 ? 370 ASN A OD1    1 
ATOM   5427 N ND2    . ASN B 2 370 ? 19.918 -4.401  12.388 1.00 60.49 ? 370 ASN A ND2    1 
ATOM   5428 H H      . ASN B 2 370 ? 22.804 -6.159  8.880  1.00 20.00 ? 370 ASN A H      1 
ATOM   5429 H HD21   . ASN B 2 370 ? 19.734 -4.749  13.280 1.00 20.00 ? 370 ASN A HD21   1 
ATOM   5430 H HD22   . ASN B 2 370 ? 19.816 -3.454  12.156 1.00 20.00 ? 370 ASN A HD22   1 
ATOM   5431 N N      . LYS B 2 371 ? 21.611 -5.338  6.796  1.00 43.08 ? 371 LYS A N      1 
ATOM   5432 C CA     . LYS B 2 371 ? 21.602 -4.766  5.462  1.00 42.84 ? 371 LYS A CA     1 
ATOM   5433 C C      . LYS B 2 371 ? 21.955 -5.800  4.408  1.00 38.28 ? 371 LYS A C      1 
ATOM   5434 O O      . LYS B 2 371 ? 23.036 -5.745  3.824  1.00 37.67 ? 371 LYS A O      1 
ATOM   5435 C CB     . LYS B 2 371 ? 22.572 -3.588  5.371  1.00 44.97 ? 371 LYS A CB     1 
ATOM   5436 C CG     . LYS B 2 371 ? 22.093 -2.311  6.037  1.00 47.39 ? 371 LYS A CG     1 
ATOM   5437 C CD     . LYS B 2 371 ? 23.136 -1.238  5.873  1.00 47.30 ? 371 LYS A CD     1 
ATOM   5438 C CE     . LYS B 2 371 ? 22.590 0.097   6.299  1.00 48.71 ? 371 LYS A CE     1 
ATOM   5439 N NZ     . LYS B 2 371 ? 23.615 1.136   6.006  1.00 48.83 ? 371 LYS A NZ     1 
ATOM   5440 H H      . LYS B 2 371 ? 22.309 -5.943  7.034  1.00 20.00 ? 371 LYS A H      1 
ATOM   5441 H HZ1    . LYS B 2 371 ? 23.965 0.980   5.027  1.00 20.00 ? 371 LYS A HZ1    1 
ATOM   5442 H HZ2    . LYS B 2 371 ? 23.162 2.069   6.041  1.00 20.00 ? 371 LYS A HZ2    1 
ATOM   5443 H HZ3    . LYS B 2 371 ? 24.384 1.072   6.671  1.00 20.00 ? 371 LYS A HZ3    1 
ATOM   5444 N N      . PRO B 2 372 ? 21.026 -6.720  4.105  1.00 35.37 ? 372 PRO A N      1 
ATOM   5445 C CA     . PRO B 2 372 ? 21.217 -7.781  3.107  1.00 33.63 ? 372 PRO A CA     1 
ATOM   5446 C C      . PRO B 2 372 ? 21.827 -7.273  1.793  1.00 32.52 ? 372 PRO A C      1 
ATOM   5447 O O      . PRO B 2 372 ? 22.583 -7.985  1.120  1.00 29.10 ? 372 PRO A O      1 
ATOM   5448 C CB     . PRO B 2 372 ? 19.796 -8.324  2.919  1.00 33.19 ? 372 PRO A CB     1 
ATOM   5449 C CG     . PRO B 2 372 ? 18.933 -7.120  3.206  1.00 32.65 ? 372 PRO A CG     1 
ATOM   5450 C CD     . PRO B 2 372 ? 19.592 -6.547  4.417  1.00 34.26 ? 372 PRO A CD     1 
ATOM   5451 N N      . GLU B 2 373 ? 21.522 -6.020  1.464  1.00 31.81 ? 373 GLU A N      1 
ATOM   5452 C CA     . GLU B 2 373 ? 22.015 -5.396  0.253  1.00 32.52 ? 373 GLU A CA     1 
ATOM   5453 C C      . GLU B 2 373 ? 23.523 -5.504  0.157  1.00 31.17 ? 373 GLU A C      1 
ATOM   5454 O O      . GLU B 2 373 ? 24.068 -5.648  -0.930 1.00 27.61 ? 373 GLU A O      1 
ATOM   5455 C CB     . GLU B 2 373 ? 21.605 -3.917  0.209  1.00 35.00 ? 373 GLU A CB     1 
ATOM   5456 C CG     . GLU B 2 373 ? 21.576 -3.228  1.573  1.00 36.63 ? 373 GLU A CG     1 
ATOM   5457 C CD     . GLU B 2 373 ? 20.195 -3.249  2.213  1.00 36.93 ? 373 GLU A CD     1 
ATOM   5458 O OE1    . GLU B 2 373 ? 19.368 -4.135  1.873  1.00 38.56 ? 373 GLU A OE1    1 
ATOM   5459 O OE2    . GLU B 2 373 ? 19.930 -2.358  3.048  1.00 38.20 ? 373 GLU A OE2    1 
ATOM   5460 H H      . GLU B 2 373 ? 20.964 -5.517  2.072  1.00 20.00 ? 373 GLU A H      1 
ATOM   5461 N N      . MET B 2 374 ? 24.194 -5.497  1.297  1.00 33.19 ? 374 MET A N      1 
ATOM   5462 C CA     . MET B 2 374 ? 25.645 -5.553  1.308  1.00 35.83 ? 374 MET A CA     1 
ATOM   5463 C C      . MET B 2 374 ? 26.275 -6.882  0.946  1.00 37.90 ? 374 MET A C      1 
ATOM   5464 O O      . MET B 2 374 ? 27.507 -7.003  0.948  1.00 37.32 ? 374 MET A O      1 
ATOM   5465 C CB     . MET B 2 374 ? 26.187 -5.043  2.641  1.00 36.37 ? 374 MET A CB     1 
ATOM   5466 C CG     . MET B 2 374 ? 25.828 -3.584  2.907  1.00 39.04 ? 374 MET A CG     1 
ATOM   5467 S SD     . MET B 2 374 ? 26.653 -2.894  4.350  1.00 40.62 ? 374 MET A SD     1 
ATOM   5468 C CE     . MET B 2 374 ? 28.312 -3.505  4.104  1.00 37.44 ? 374 MET A CE     1 
ATOM   5469 H H      . MET B 2 374 ? 23.714 -5.441  2.129  1.00 20.00 ? 374 MET A H      1 
ATOM   5470 N N      . GLY B 2 375 ? 25.439 -7.868  0.632  1.00 41.43 ? 375 GLY A N      1 
ATOM   5471 C CA     . GLY B 2 375 ? 25.943 -9.177  0.242  1.00 42.65 ? 375 GLY A CA     1 
ATOM   5472 C C      . GLY B 2 375 ? 26.166 -10.219 1.331  1.00 41.24 ? 375 GLY A C      1 
ATOM   5473 O O      . GLY B 2 375 ? 25.764 -10.033 2.489  1.00 42.78 ? 375 GLY A O      1 
ATOM   5474 H H      . GLY B 2 375 ? 24.478 -7.715  0.662  1.00 20.00 ? 375 GLY A H      1 
ATOM   5475 N N      . SER B 2 376 ? 26.793 -11.330 0.942  1.00 40.46 ? 376 SER A N      1 
ATOM   5476 C CA     . SER B 2 376 ? 27.092 -12.425 1.861  1.00 38.11 ? 376 SER A CA     1 
ATOM   5477 C C      . SER B 2 376 ? 28.421 -13.038 1.460  1.00 34.78 ? 376 SER A C      1 
ATOM   5478 O O      . SER B 2 376 ? 28.988 -12.669 0.422  1.00 36.27 ? 376 SER A O      1 
ATOM   5479 C CB     . SER B 2 376 ? 26.011 -13.493 1.799  1.00 40.26 ? 376 SER A CB     1 
ATOM   5480 O OG     . SER B 2 376 ? 26.144 -14.276 0.626  1.00 39.21 ? 376 SER A OG     1 
ATOM   5481 H H      . SER B 2 376 ? 27.123 -11.409 0.026  1.00 20.00 ? 376 SER A H      1 
ATOM   5482 H HG     . SER B 2 376 ? 25.464 -14.956 0.601  1.00 20.00 ? 376 SER A HG     1 
ATOM   5483 N N      . ARG B 2 377 ? 28.910 -13.983 2.258  1.00 31.04 ? 377 ARG A N      1 
ATOM   5484 C CA     . ARG B 2 377 ? 30.183 -14.635 1.959  1.00 28.55 ? 377 ARG A CA     1 
ATOM   5485 C C      . ARG B 2 377 ? 30.232 -16.072 2.452  1.00 28.18 ? 377 ARG A C      1 
ATOM   5486 O O      . ARG B 2 377 ? 29.406 -16.492 3.274  1.00 28.37 ? 377 ARG A O      1 
ATOM   5487 C CB     . ARG B 2 377 ? 31.364 -13.841 2.535  1.00 27.93 ? 377 ARG A CB     1 
ATOM   5488 C CG     . ARG B 2 377 ? 31.451 -13.839 4.055  1.00 24.73 ? 377 ARG A CG     1 
ATOM   5489 C CD     . ARG B 2 377 ? 32.467 -12.836 4.578  1.00 22.50 ? 377 ARG A CD     1 
ATOM   5490 N NE     . ARG B 2 377 ? 32.548 -12.876 6.033  1.00 20.71 ? 377 ARG A NE     1 
ATOM   5491 C CZ     . ARG B 2 377 ? 31.562 -12.505 6.842  1.00 21.21 ? 377 ARG A CZ     1 
ATOM   5492 N NH1    . ARG B 2 377 ? 30.439 -12.017 6.340  1.00 21.57 ? 377 ARG A NH1    1 
ATOM   5493 N NH2    . ARG B 2 377 ? 31.714 -12.586 8.156  1.00 20.92 ? 377 ARG A NH2    1 
ATOM   5494 H H      . ARG B 2 377 ? 28.430 -14.255 3.038  1.00 20.00 ? 377 ARG A H      1 
ATOM   5495 H HE     . ARG B 2 377 ? 33.404 -13.135 6.410  1.00 20.00 ? 377 ARG A HE     1 
ATOM   5496 H HH11   . ARG B 2 377 ? 30.310 -11.915 5.370  1.00 20.00 ? 377 ARG A HH11   1 
ATOM   5497 H HH12   . ARG B 2 377 ? 29.715 -11.751 6.986  1.00 20.00 ? 377 ARG A HH12   1 
ATOM   5498 H HH21   . ARG B 2 377 ? 32.620 -12.878 8.513  1.00 20.00 ? 377 ARG A HH21   1 
ATOM   5499 H HH22   . ARG B 2 377 ? 31.021 -12.295 8.778  1.00 20.00 ? 377 ARG A HH22   1 
ATOM   5500 N N      . GLN B 2 378 ? 31.254 -16.790 1.990  1.00 29.36 ? 378 GLN A N      1 
ATOM   5501 C CA     . GLN B 2 378 ? 31.466 -18.196 2.322  1.00 29.85 ? 378 GLN A CA     1 
ATOM   5502 C C      . GLN B 2 378 ? 32.597 -18.382 3.340  1.00 29.66 ? 378 GLN A C      1 
ATOM   5503 O O      . GLN B 2 378 ? 33.781 -18.357 2.980  1.00 28.79 ? 378 GLN A O      1 
ATOM   5504 C CB     . GLN B 2 378 ? 31.802 -18.953 1.042  1.00 28.10 ? 378 GLN A CB     1 
ATOM   5505 C CG     . GLN B 2 378 ? 30.988 -20.196 0.840  1.00 29.11 ? 378 GLN A CG     1 
ATOM   5506 C CD     . GLN B 2 378 ? 29.502 -19.956 0.930  1.00 29.68 ? 378 GLN A CD     1 
ATOM   5507 O OE1    . GLN B 2 378 ? 29.011 -18.921 0.501  1.00 30.75 ? 378 GLN A OE1    1 
ATOM   5508 N NE2    . GLN B 2 378 ? 28.779 -20.919 1.472  1.00 27.75 ? 378 GLN A NE2    1 
ATOM   5509 H H      . GLN B 2 378 ? 31.895 -16.348 1.389  1.00 20.00 ? 378 GLN A H      1 
ATOM   5510 H HE21   . GLN B 2 378 ? 27.820 -20.770 1.523  1.00 20.00 ? 378 GLN A HE21   1 
ATOM   5511 H HE22   . GLN B 2 378 ? 29.220 -21.736 1.770  1.00 20.00 ? 378 GLN A HE22   1 
ATOM   5512 N N      . VAL B 2 379 ? 32.219 -18.621 4.597  1.00 25.83 ? 379 VAL A N      1 
ATOM   5513 C CA     . VAL B 2 379 ? 33.162 -18.790 5.710  1.00 24.05 ? 379 VAL A CA     1 
ATOM   5514 C C      . VAL B 2 379 ? 33.313 -20.249 6.089  1.00 21.30 ? 379 VAL A C      1 
ATOM   5515 O O      . VAL B 2 379 ? 32.347 -20.910 6.449  1.00 21.72 ? 379 VAL A O      1 
ATOM   5516 C CB     . VAL B 2 379 ? 32.678 -18.052 6.976  1.00 28.25 ? 379 VAL A CB     1 
ATOM   5517 C CG1    . VAL B 2 379 ? 33.790 -17.981 7.991  1.00 28.88 ? 379 VAL A CG1    1 
ATOM   5518 C CG2    . VAL B 2 379 ? 32.172 -16.658 6.626  1.00 29.64 ? 379 VAL A CG2    1 
ATOM   5519 H H      . VAL B 2 379 ? 31.262 -18.701 4.769  1.00 20.00 ? 379 VAL A H      1 
ATOM   5520 N N      . PRO B 2 380 ? 34.551 -20.755 6.084  1.00 20.30 ? 380 PRO A N      1 
ATOM   5521 C CA     . PRO B 2 380 ? 34.798 -22.156 6.430  1.00 18.62 ? 380 PRO A CA     1 
ATOM   5522 C C      . PRO B 2 380 ? 34.495 -22.597 7.856  1.00 19.70 ? 380 PRO A C      1 
ATOM   5523 O O      . PRO B 2 380 ? 35.065 -22.066 8.808  1.00 18.64 ? 380 PRO A O      1 
ATOM   5524 C CB     . PRO B 2 380 ? 36.290 -22.316 6.110  1.00 15.79 ? 380 PRO A CB     1 
ATOM   5525 C CG     . PRO B 2 380 ? 36.837 -20.969 6.320  1.00 16.78 ? 380 PRO A CG     1 
ATOM   5526 C CD     . PRO B 2 380 ? 35.798 -20.103 5.656  1.00 19.43 ? 380 PRO A CD     1 
ATOM   5527 N N      . PHE B 2 381 ? 33.583 -23.558 8.005  1.00 22.24 ? 381 PHE A N      1 
ATOM   5528 C CA     . PHE B 2 381 ? 33.267 -24.102 9.328  1.00 24.76 ? 381 PHE A CA     1 
ATOM   5529 C C      . PHE B 2 381 ? 34.114 -25.348 9.505  1.00 26.03 ? 381 PHE A C      1 
ATOM   5530 O O      . PHE B 2 381 ? 34.601 -25.915 8.528  1.00 27.93 ? 381 PHE A O      1 
ATOM   5531 C CB     . PHE B 2 381 ? 31.810 -24.504 9.465  1.00 26.53 ? 381 PHE A CB     1 
ATOM   5532 C CG     . PHE B 2 381 ? 31.461 -25.017 10.831 1.00 28.18 ? 381 PHE A CG     1 
ATOM   5533 C CD1    . PHE B 2 381 ? 31.246 -24.131 11.885 1.00 31.81 ? 381 PHE A CD1    1 
ATOM   5534 C CD2    . PHE B 2 381 ? 31.368 -26.383 11.079 1.00 31.88 ? 381 PHE A CD2    1 
ATOM   5535 C CE1    . PHE B 2 381 ? 30.948 -24.594 13.163 1.00 31.94 ? 381 PHE A CE1    1 
ATOM   5536 C CE2    . PHE B 2 381 ? 31.069 -26.857 12.358 1.00 31.29 ? 381 PHE A CE2    1 
ATOM   5537 C CZ     . PHE B 2 381 ? 30.860 -25.959 13.400 1.00 31.06 ? 381 PHE A CZ     1 
ATOM   5538 H H      . PHE B 2 381 ? 33.114 -23.895 7.221  1.00 20.00 ? 381 PHE A H      1 
ATOM   5539 N N      . SER B 2 382 ? 34.232 -25.817 10.734 1.00 26.36 ? 382 SER A N      1 
ATOM   5540 C CA     . SER B 2 382 ? 35.041 -26.991 10.983 1.00 26.12 ? 382 SER A CA     1 
ATOM   5541 C C      . SER B 2 382 ? 34.721 -27.571 12.361 1.00 26.54 ? 382 SER A C      1 
ATOM   5542 O O      . SER B 2 382 ? 33.742 -27.175 13.003 1.00 26.07 ? 382 SER A O      1 
ATOM   5543 C CB     . SER B 2 382 ? 36.519 -26.598 10.879 1.00 26.73 ? 382 SER A CB     1 
ATOM   5544 O OG     . SER B 2 382 ? 37.382 -27.720 10.851 1.00 28.14 ? 382 SER A OG     1 
ATOM   5545 H H      . SER B 2 382 ? 33.775 -25.391 11.476 1.00 20.00 ? 382 SER A H      1 
ATOM   5546 H HG     . SER B 2 382 ? 38.298 -27.425 10.742 1.00 20.00 ? 382 SER A HG     1 
ATOM   5547 N N      . GLY B 2 383 ? 35.542 -28.523 12.800 1.00 29.26 ? 383 GLY A N      1 
ATOM   5548 C CA     . GLY B 2 383 ? 35.345 -29.148 14.100 1.00 30.30 ? 383 GLY A CA     1 
ATOM   5549 C C      . GLY B 2 383 ? 36.318 -28.641 15.143 1.00 32.41 ? 383 GLY A C      1 
ATOM   5550 O O      . GLY B 2 383 ? 35.954 -28.484 16.299 1.00 30.35 ? 383 GLY A O      1 
ATOM   5551 H H      . GLY B 2 383 ? 36.297 -28.801 12.228 1.00 20.00 ? 383 GLY A H      1 
ATOM   5552 N N      . GLU B 2 384 ? 37.572 -28.440 14.744 1.00 34.35 ? 384 GLU A N      1 
ATOM   5553 C CA     . GLU B 2 384 ? 38.605 -27.914 15.633 1.00 37.26 ? 384 GLU A CA     1 
ATOM   5554 C C      . GLU B 2 384 ? 38.656 -26.386 15.401 1.00 33.60 ? 384 GLU A C      1 
ATOM   5555 O O      . GLU B 2 384 ? 39.427 -25.885 14.567 1.00 32.45 ? 384 GLU A O      1 
ATOM   5556 C CB     . GLU B 2 384 ? 39.950 -28.562 15.310 1.00 44.96 ? 384 GLU A CB     1 
ATOM   5557 C CG     . GLU B 2 384 ? 41.129 -28.010 16.115 1.00 52.59 ? 384 GLU A CG     1 
ATOM   5558 C CD     . GLU B 2 384 ? 42.475 -28.678 15.781 1.00 59.08 ? 384 GLU A CD     1 
ATOM   5559 O OE1    . GLU B 2 384 ? 43.054 -28.380 14.705 1.00 59.91 ? 384 GLU A OE1    1 
ATOM   5560 O OE2    . GLU B 2 384 ? 42.963 -29.481 16.611 1.00 60.69 ? 384 GLU A OE2    1 
ATOM   5561 H H      . GLU B 2 384 ? 37.799 -28.630 13.815 1.00 20.00 ? 384 GLU A H      1 
ATOM   5562 N N      . ILE B 2 385 ? 37.798 -25.653 16.100 1.00 28.89 ? 385 ILE A N      1 
ATOM   5563 C CA     . ILE B 2 385 ? 37.749 -24.211 15.933 1.00 25.53 ? 385 ILE A CA     1 
ATOM   5564 C C      . ILE B 2 385 ? 38.566 -23.387 16.952 1.00 24.97 ? 385 ILE A C      1 
ATOM   5565 O O      . ILE B 2 385 ? 39.406 -23.932 17.680 1.00 24.55 ? 385 ILE A O      1 
ATOM   5566 C CB     . ILE B 2 385 ? 36.289 -23.730 15.887 1.00 21.75 ? 385 ILE A CB     1 
ATOM   5567 C CG1    . ILE B 2 385 ? 35.694 -23.689 17.280 1.00 19.09 ? 385 ILE A CG1    1 
ATOM   5568 C CG2    . ILE B 2 385 ? 35.461 -24.674 15.013 1.00 21.83 ? 385 ILE A CG2    1 
ATOM   5569 C CD1    . ILE B 2 385 ? 34.259 -23.264 17.264 1.00 22.23 ? 385 ILE A CD1    1 
ATOM   5570 H H      . ILE B 2 385 ? 37.191 -26.082 16.737 1.00 20.00 ? 385 ILE A H      1 
ATOM   5571 N N      . TRP B 2 386 ? 38.345 -22.068 16.954 1.00 24.51 ? 386 TRP A N      1 
ATOM   5572 C CA     . TRP B 2 386 ? 39.009 -21.110 17.846 1.00 20.93 ? 386 TRP A CA     1 
ATOM   5573 C C      . TRP B 2 386 ? 37.952 -20.268 18.508 1.00 22.84 ? 386 TRP A C      1 
ATOM   5574 O O      . TRP B 2 386 ? 37.019 -19.797 17.837 1.00 24.18 ? 386 TRP A O      1 
ATOM   5575 C CB     . TRP B 2 386 ? 39.849 -20.129 17.044 1.00 17.18 ? 386 TRP A CB     1 
ATOM   5576 C CG     . TRP B 2 386 ? 41.205 -20.574 16.724 1.00 16.18 ? 386 TRP A CG     1 
ATOM   5577 C CD1    . TRP B 2 386 ? 41.801 -20.549 15.499 1.00 15.87 ? 386 TRP A CD1    1 
ATOM   5578 C CD2    . TRP B 2 386 ? 42.186 -21.057 17.635 1.00 14.27 ? 386 TRP A CD2    1 
ATOM   5579 N NE1    . TRP B 2 386 ? 43.103 -20.979 15.589 1.00 13.89 ? 386 TRP A NE1    1 
ATOM   5580 C CE2    . TRP B 2 386 ? 43.365 -21.294 16.897 1.00 15.22 ? 386 TRP A CE2    1 
ATOM   5581 C CE3    . TRP B 2 386 ? 42.183 -21.306 19.014 1.00 15.13 ? 386 TRP A CE3    1 
ATOM   5582 C CZ2    . TRP B 2 386 ? 44.534 -21.765 17.480 1.00 15.26 ? 386 TRP A CZ2    1 
ATOM   5583 C CZ3    . TRP B 2 386 ? 43.337 -21.774 19.601 1.00 16.37 ? 386 TRP A CZ3    1 
ATOM   5584 C CH2    . TRP B 2 386 ? 44.506 -21.999 18.836 1.00 17.17 ? 386 TRP A CH2    1 
ATOM   5585 H H      . TRP B 2 386 ? 37.698 -21.697 16.322 1.00 20.00 ? 386 TRP A H      1 
ATOM   5586 H HE1    . TRP B 2 386 ? 43.729 -21.049 14.832 1.00 20.00 ? 386 TRP A HE1    1 
ATOM   5587 N N      . ILE B 2 387 ? 38.047 -20.109 19.817 1.00 24.39 ? 387 ILE A N      1 
ATOM   5588 C CA     . ILE B 2 387 ? 37.095 -19.236 20.494 1.00 28.15 ? 387 ILE A CA     1 
ATOM   5589 C C      . ILE B 2 387 ? 37.801 -18.313 21.469 1.00 30.22 ? 387 ILE A C      1 
ATOM   5590 O O      . ILE B 2 387 ? 38.967 -18.522 21.835 1.00 29.35 ? 387 ILE A O      1 
ATOM   5591 C CB     . ILE B 2 387 ? 35.923 -19.957 21.223 1.00 27.33 ? 387 ILE A CB     1 
ATOM   5592 C CG1    . ILE B 2 387 ? 36.428 -20.810 22.385 1.00 28.13 ? 387 ILE A CG1    1 
ATOM   5593 C CG2    . ILE B 2 387 ? 35.055 -20.715 20.234 1.00 25.88 ? 387 ILE A CG2    1 
ATOM   5594 C CD1    . ILE B 2 387 ? 35.483 -20.783 23.598 1.00 26.90 ? 387 ILE A CD1    1 
ATOM   5595 H H      . ILE B 2 387 ? 38.730 -20.586 20.349 1.00 20.00 ? 387 ILE A H      1 
ATOM   5596 N N      . ASP B 2 388 ? 37.121 -17.228 21.808 1.00 32.33 ? 388 ASP A N      1 
ATOM   5597 C CA     . ASP B 2 388 ? 37.667 -16.256 22.719 1.00 34.02 ? 388 ASP A CA     1 
ATOM   5598 C C      . ASP B 2 388 ? 37.480 -16.743 24.150 1.00 34.50 ? 388 ASP A C      1 
ATOM   5599 O O      . ASP B 2 388 ? 36.368 -17.117 24.558 1.00 32.02 ? 388 ASP A O      1 
ATOM   5600 C CB     . ASP B 2 388 ? 36.992 -14.908 22.488 1.00 35.18 ? 388 ASP A CB     1 
ATOM   5601 C CG     . ASP B 2 388 ? 37.632 -13.783 23.279 1.00 34.30 ? 388 ASP A CG     1 
ATOM   5602 O OD1    . ASP B 2 388 ? 38.875 -13.673 23.249 1.00 36.74 ? 388 ASP A OD1    1 
ATOM   5603 O OD2    . ASP B 2 388 ? 36.884 -12.997 23.913 1.00 36.79 ? 388 ASP A OD2    1 
ATOM   5604 H H      . ASP B 2 388 ? 36.226 -17.105 21.451 1.00 20.00 ? 388 ASP A H      1 
ATOM   5605 N N      . ARG B 2 389 ? 38.588 -16.725 24.889 1.00 35.91 ? 389 ARG A N      1 
ATOM   5606 C CA     . ARG B 2 389 ? 38.647 -17.168 26.272 1.00 34.38 ? 389 ARG A CA     1 
ATOM   5607 C C      . ARG B 2 389 ? 37.404 -16.756 27.042 1.00 29.79 ? 389 ARG A C      1 
ATOM   5608 O O      . ARG B 2 389 ? 36.533 -17.569 27.297 1.00 28.68 ? 389 ARG A O      1 
ATOM   5609 C CB     . ARG B 2 389 ? 39.895 -16.600 26.944 1.00 39.70 ? 389 ARG A CB     1 
ATOM   5610 C CG     . ARG B 2 389 ? 40.610 -17.561 27.888 1.00 45.63 ? 389 ARG A CG     1 
ATOM   5611 C CD     . ARG B 2 389 ? 41.610 -18.471 27.167 1.00 48.76 ? 389 ARG A CD     1 
ATOM   5612 N NE     . ARG B 2 389 ? 42.640 -17.724 26.443 1.00 51.67 ? 389 ARG A NE     1 
ATOM   5613 C CZ     . ARG B 2 389 ? 43.868 -18.181 26.188 1.00 52.50 ? 389 ARG A CZ     1 
ATOM   5614 N NH1    . ARG B 2 389 ? 44.252 -19.381 26.616 1.00 54.26 ? 389 ARG A NH1    1 
ATOM   5615 N NH2    . ARG B 2 389 ? 44.726 -17.426 25.513 1.00 55.78 ? 389 ARG A NH2    1 
ATOM   5616 H H      . ARG B 2 389 ? 39.412 -16.423 24.468 1.00 20.00 ? 389 ARG A H      1 
ATOM   5617 H HE     . ARG B 2 389 ? 42.426 -16.821 26.147 1.00 20.00 ? 389 ARG A HE     1 
ATOM   5618 H HH11   . ARG B 2 389 ? 43.621 -19.961 27.127 1.00 20.00 ? 389 ARG A HH11   1 
ATOM   5619 H HH12   . ARG B 2 389 ? 45.169 -19.725 26.390 1.00 20.00 ? 389 ARG A HH12   1 
ATOM   5620 H HH21   . ARG B 2 389 ? 44.456 -16.516 25.204 1.00 20.00 ? 389 ARG A HH21   1 
ATOM   5621 H HH22   . ARG B 2 389 ? 45.643 -17.775 25.301 1.00 20.00 ? 389 ARG A HH22   1 
ATOM   5622 N N      . ALA B 2 390 ? 37.263 -15.467 27.299 1.00 27.77 ? 390 ALA A N      1 
ATOM   5623 C CA     . ALA B 2 390 ? 36.126 -14.967 28.074 1.00 27.02 ? 390 ALA A CA     1 
ATOM   5624 C C      . ALA B 2 390 ? 34.725 -15.403 27.659 1.00 29.21 ? 390 ALA A C      1 
ATOM   5625 O O      . ALA B 2 390 ? 33.745 -14.943 28.235 1.00 29.63 ? 390 ALA A O      1 
ATOM   5626 C CB     . ALA B 2 390 ? 36.185 -13.448 28.169 1.00 26.00 ? 390 ALA A CB     1 
ATOM   5627 H H      . ALA B 2 390 ? 37.934 -14.842 26.969 1.00 20.00 ? 390 ALA A H      1 
ATOM   5628 N N      . ASP B 2 391 ? 34.614 -16.234 26.638 1.00 32.79 ? 391 ASP A N      1 
ATOM   5629 C CA     . ASP B 2 391 ? 33.308 -16.685 26.217 1.00 36.43 ? 391 ASP A CA     1 
ATOM   5630 C C      . ASP B 2 391 ? 32.925 -17.991 26.876 1.00 38.41 ? 391 ASP A C      1 
ATOM   5631 O O      . ASP B 2 391 ? 31.756 -18.384 26.863 1.00 37.03 ? 391 ASP A O      1 
ATOM   5632 C CB     . ASP B 2 391 ? 33.235 -16.786 24.699 1.00 39.24 ? 391 ASP A CB     1 
ATOM   5633 C CG     . ASP B 2 391 ? 33.243 -15.425 24.042 1.00 38.65 ? 391 ASP A CG     1 
ATOM   5634 O OD1    . ASP B 2 391 ? 32.288 -14.657 24.296 1.00 40.96 ? 391 ASP A OD1    1 
ATOM   5635 O OD2    . ASP B 2 391 ? 34.206 -15.114 23.311 1.00 39.36 ? 391 ASP A OD2    1 
ATOM   5636 H H      . ASP B 2 391 ? 35.394 -16.559 26.158 1.00 20.00 ? 391 ASP A H      1 
ATOM   5637 N N      . PHE B 2 392 ? 33.911 -18.703 27.403 1.00 43.61 ? 392 PHE A N      1 
ATOM   5638 C CA     . PHE B 2 392 ? 33.630 -19.945 28.095 1.00 47.79 ? 392 PHE A CA     1 
ATOM   5639 C C      . PHE B 2 392 ? 33.746 -19.746 29.592 1.00 49.77 ? 392 PHE A C      1 
ATOM   5640 O O      . PHE B 2 392 ? 34.703 -19.131 30.078 1.00 48.60 ? 392 PHE A O      1 
ATOM   5641 C CB     . PHE B 2 392 ? 34.569 -21.083 27.694 1.00 48.43 ? 392 PHE A CB     1 
ATOM   5642 C CG     . PHE B 2 392 ? 34.278 -22.363 28.435 1.00 47.49 ? 392 PHE A CG     1 
ATOM   5643 C CD1    . PHE B 2 392 ? 33.332 -23.262 27.947 1.00 48.78 ? 392 PHE A CD1    1 
ATOM   5644 C CD2    . PHE B 2 392 ? 34.872 -22.623 29.671 1.00 48.65 ? 392 PHE A CD2    1 
ATOM   5645 C CE1    . PHE B 2 392 ? 32.971 -24.399 28.680 1.00 46.61 ? 392 PHE A CE1    1 
ATOM   5646 C CE2    . PHE B 2 392 ? 34.518 -23.756 30.414 1.00 46.10 ? 392 PHE A CE2    1 
ATOM   5647 C CZ     . PHE B 2 392 ? 33.562 -24.644 29.913 1.00 44.98 ? 392 PHE A CZ     1 
ATOM   5648 H H      . PHE B 2 392 ? 34.828 -18.382 27.351 1.00 20.00 ? 392 PHE A H      1 
ATOM   5649 N N      . ARG B 2 393 ? 32.800 -20.329 30.320 1.00 51.14 ? 393 ARG A N      1 
ATOM   5650 C CA     . ARG B 2 393 ? 32.783 -20.265 31.773 1.00 52.64 ? 393 ARG A CA     1 
ATOM   5651 C C      . ARG B 2 393 ? 32.446 -21.660 32.337 1.00 51.15 ? 393 ARG A C      1 
ATOM   5652 O O      . ARG B 2 393 ? 31.395 -22.245 32.042 1.00 48.68 ? 393 ARG A O      1 
ATOM   5653 C CB     . ARG B 2 393 ? 31.782 -19.222 32.257 1.00 54.79 ? 393 ARG A CB     1 
ATOM   5654 C CG     . ARG B 2 393 ? 32.172 -18.576 33.561 1.00 56.64 ? 393 ARG A CG     1 
ATOM   5655 C CD     . ARG B 2 393 ? 32.499 -17.108 33.396 1.00 59.96 ? 393 ARG A CD     1 
ATOM   5656 N NE     . ARG B 2 393 ? 33.712 -16.874 32.603 1.00 61.58 ? 393 ARG A NE     1 
ATOM   5657 C CZ     . ARG B 2 393 ? 34.094 -15.677 32.156 1.00 60.65 ? 393 ARG A CZ     1 
ATOM   5658 N NH1    . ARG B 2 393 ? 33.336 -14.604 32.393 1.00 59.48 ? 393 ARG A NH1    1 
ATOM   5659 N NH2    . ARG B 2 393 ? 35.220 -15.552 31.456 1.00 61.77 ? 393 ARG A NH2    1 
ATOM   5660 H H      . ARG B 2 393 ? 32.108 -20.825 29.881 1.00 20.00 ? 393 ARG A H      1 
ATOM   5661 H HE     . ARG B 2 393 ? 34.292 -17.634 32.394 1.00 20.00 ? 393 ARG A HE     1 
ATOM   5662 H HH11   . ARG B 2 393 ? 32.499 -14.689 32.945 1.00 20.00 ? 393 ARG A HH11   1 
ATOM   5663 H HH12   . ARG B 2 393 ? 33.627 -13.696 32.088 1.00 20.00 ? 393 ARG A HH12   1 
ATOM   5664 H HH21   . ARG B 2 393 ? 35.784 -16.343 31.266 1.00 20.00 ? 393 ARG A HH21   1 
ATOM   5665 H HH22   . ARG B 2 393 ? 35.499 -14.638 31.131 1.00 20.00 ? 393 ARG A HH22   1 
ATOM   5666 N N      . GLU B 2 394 ? 33.387 -22.215 33.095 1.00 50.72 ? 394 GLU A N      1 
ATOM   5667 C CA     . GLU B 2 394 ? 33.227 -23.526 33.719 1.00 50.06 ? 394 GLU A CA     1 
ATOM   5668 C C      . GLU B 2 394 ? 32.148 -23.419 34.798 1.00 47.61 ? 394 GLU A C      1 
ATOM   5669 O O      . GLU B 2 394 ? 31.456 -24.388 35.113 1.00 44.83 ? 394 GLU A O      1 
ATOM   5670 C CB     . GLU B 2 394 ? 34.553 -23.927 34.357 1.00 50.41 ? 394 GLU A CB     1 
ATOM   5671 C CG     . GLU B 2 394 ? 34.828 -25.407 34.399 1.00 52.81 ? 394 GLU A CG     1 
ATOM   5672 C CD     . GLU B 2 394 ? 36.220 -25.718 34.912 1.00 53.81 ? 394 GLU A CD     1 
ATOM   5673 O OE1    . GLU B 2 394 ? 37.087 -24.814 34.877 1.00 54.71 ? 394 GLU A OE1    1 
ATOM   5674 O OE2    . GLU B 2 394 ? 36.453 -26.867 35.354 1.00 54.48 ? 394 GLU A OE2    1 
ATOM   5675 H H      . GLU B 2 394 ? 34.234 -21.737 33.222 1.00 20.00 ? 394 GLU A H      1 
ATOM   5676 N N      . GLU B 2 395 ? 32.010 -22.211 35.335 1.00 46.90 ? 395 GLU A N      1 
ATOM   5677 C CA     . GLU B 2 395 ? 31.057 -21.898 36.388 1.00 47.85 ? 395 GLU A CA     1 
ATOM   5678 C C      . GLU B 2 395 ? 30.423 -20.532 36.150 1.00 44.50 ? 395 GLU A C      1 
ATOM   5679 O O      . GLU B 2 395 ? 31.134 -19.542 36.043 1.00 41.70 ? 395 GLU A O      1 
ATOM   5680 C CB     . GLU B 2 395 ? 31.784 -21.873 37.743 1.00 52.91 ? 395 GLU A CB     1 
ATOM   5681 C CG     . GLU B 2 395 ? 33.322 -21.659 37.694 1.00 58.52 ? 395 GLU A CG     1 
ATOM   5682 C CD     . GLU B 2 395 ? 33.775 -20.373 36.995 1.00 58.66 ? 395 GLU A CD     1 
ATOM   5683 O OE1    . GLU B 2 395 ? 33.446 -19.263 37.479 1.00 64.76 ? 395 GLU A OE1    1 
ATOM   5684 O OE2    . GLU B 2 395 ? 34.485 -20.482 35.966 1.00 59.54 ? 395 GLU A OE2    1 
ATOM   5685 H H      . GLU B 2 395 ? 32.564 -21.485 35.001 1.00 20.00 ? 395 GLU A H      1 
ATOM   5686 N N      . ALA B 2 396 ? 29.097 -20.454 36.108 1.00 43.47 ? 396 ALA A N      1 
ATOM   5687 C CA     . ALA B 2 396 ? 28.469 -19.153 35.881 1.00 43.96 ? 396 ALA A CA     1 
ATOM   5688 C C      . ALA B 2 396 ? 27.041 -19.028 36.395 1.00 44.90 ? 396 ALA A C      1 
ATOM   5689 O O      . ALA B 2 396 ? 26.481 -19.983 36.921 1.00 45.81 ? 396 ALA A O      1 
ATOM   5690 C CB     . ALA B 2 396 ? 28.537 -18.796 34.410 1.00 46.18 ? 396 ALA A CB     1 
ATOM   5691 H H      . ALA B 2 396 ? 28.529 -21.248 36.249 1.00 20.00 ? 396 ALA A H      1 
ATOM   5692 N N      . ASN B 2 397 ? 26.452 -17.849 36.223 1.00 47.30 ? 397 ASN A N      1 
ATOM   5693 C CA     . ASN B 2 397 ? 25.087 -17.580 36.674 1.00 50.55 ? 397 ASN A CA     1 
ATOM   5694 C C      . ASN B 2 397 ? 24.177 -17.200 35.511 1.00 52.22 ? 397 ASN A C      1 
ATOM   5695 O O      . ASN B 2 397 ? 24.657 -16.774 34.460 1.00 56.14 ? 397 ASN A O      1 
ATOM   5696 C CB     . ASN B 2 397 ? 25.088 -16.445 37.712 1.00 53.31 ? 397 ASN A CB     1 
ATOM   5697 C CG     . ASN B 2 397 ? 25.515 -15.103 37.115 1.00 53.20 ? 397 ASN A CG     1 
ATOM   5698 O OD1    . ASN B 2 397 ? 26.556 -15.009 36.462 1.00 53.50 ? 397 ASN A OD1    1 
ATOM   5699 N ND2    . ASN B 2 397 ? 24.700 -14.070 37.318 1.00 54.91 ? 397 ASN A ND2    1 
ATOM   5700 H H      . ASN B 2 397 ? 26.941 -17.132 35.768 1.00 20.00 ? 397 ASN A H      1 
ATOM   5701 H HD21   . ASN B 2 397 ? 24.996 -13.210 36.939 1.00 20.00 ? 397 ASN A HD21   1 
ATOM   5702 H HD22   . ASN B 2 397 ? 23.894 -14.184 37.839 1.00 20.00 ? 397 ASN A HD22   1 
ATOM   5703 N N      . LYS B 2 398 ? 22.867 -17.247 35.761 1.00 54.55 ? 398 LYS A N      1 
ATOM   5704 C CA     . LYS B 2 398 ? 21.828 -16.918 34.771 1.00 54.34 ? 398 LYS A CA     1 
ATOM   5705 C C      . LYS B 2 398 ? 22.163 -15.737 33.847 1.00 53.88 ? 398 LYS A C      1 
ATOM   5706 O O      . LYS B 2 398 ? 21.783 -15.723 32.662 1.00 54.57 ? 398 LYS A O      1 
ATOM   5707 C CB     . LYS B 2 398 ? 20.484 -16.648 35.474 1.00 55.46 ? 398 LYS A CB     1 
ATOM   5708 C CG     . LYS B 2 398 ? 19.391 -16.187 34.520 1.00 56.89 ? 398 LYS A CG     1 
ATOM   5709 C CD     . LYS B 2 398 ? 18.080 -15.835 35.201 1.00 57.87 ? 398 LYS A CD     1 
ATOM   5710 C CE     . LYS B 2 398 ? 17.114 -15.270 34.162 1.00 58.80 ? 398 LYS A CE     1 
ATOM   5711 N NZ     . LYS B 2 398 ? 15.770 -14.984 34.712 1.00 57.52 ? 398 LYS A NZ     1 
ATOM   5712 H H      . LYS B 2 398 ? 22.581 -17.565 36.635 1.00 20.00 ? 398 LYS A H      1 
ATOM   5713 H HZ1    . LYS B 2 398 ? 15.865 -14.478 35.595 1.00 20.00 ? 398 LYS A HZ1    1 
ATOM   5714 H HZ2    . LYS B 2 398 ? 15.231 -14.425 34.017 1.00 20.00 ? 398 LYS A HZ2    1 
ATOM   5715 H HZ3    . LYS B 2 398 ? 15.259 -15.890 34.870 1.00 20.00 ? 398 LYS A HZ3    1 
ATOM   5716 N N      . GLN B 2 399 ? 22.812 -14.722 34.413 1.00 52.84 ? 399 GLN A N      1 
ATOM   5717 C CA     . GLN B 2 399 ? 23.195 -13.553 33.639 1.00 50.26 ? 399 GLN A CA     1 
ATOM   5718 C C      . GLN B 2 399 ? 24.077 -14.006 32.472 1.00 45.80 ? 399 GLN A C      1 
ATOM   5719 O O      . GLN B 2 399 ? 23.720 -13.828 31.299 1.00 42.90 ? 399 GLN A O      1 
ATOM   5720 C CB     . GLN B 2 399 ? 23.929 -12.558 34.536 1.00 51.99 ? 399 GLN A CB     1 
ATOM   5721 C CG     . GLN B 2 399 ? 23.065 -12.002 35.667 1.00 51.03 ? 399 GLN A CG     1 
ATOM   5722 C CD     . GLN B 2 399 ? 22.019 -11.016 35.167 1.00 50.52 ? 399 GLN A CD     1 
ATOM   5723 O OE1    . GLN B 2 399 ? 21.204 -11.344 34.302 1.00 48.70 ? 399 GLN A OE1    1 
ATOM   5724 N NE2    . GLN B 2 399 ? 22.057 -9.788  35.692 1.00 48.94 ? 399 GLN A NE2    1 
ATOM   5725 H H      . GLN B 2 399 ? 23.053 -14.779 35.341 1.00 20.00 ? 399 GLN A H      1 
ATOM   5726 H HE21   . GLN B 2 399 ? 21.394 -9.139  35.378 1.00 20.00 ? 399 GLN A HE21   1 
ATOM   5727 H HE22   . GLN B 2 399 ? 22.739 -9.561  36.363 1.00 20.00 ? 399 GLN A HE22   1 
ATOM   5728 N N      . TYR B 2 400 ? 25.222 -14.598 32.801 1.00 42.27 ? 400 TYR A N      1 
ATOM   5729 C CA     . TYR B 2 400 ? 26.166 -15.093 31.805 1.00 41.48 ? 400 TYR A CA     1 
ATOM   5730 C C      . TYR B 2 400 ? 25.418 -15.837 30.700 1.00 42.30 ? 400 TYR A C      1 
ATOM   5731 O O      . TYR B 2 400 ? 24.895 -16.919 30.939 1.00 41.90 ? 400 TYR A O      1 
ATOM   5732 C CB     . TYR B 2 400 ? 27.155 -16.034 32.473 1.00 39.24 ? 400 TYR A CB     1 
ATOM   5733 C CG     . TYR B 2 400 ? 28.368 -16.351 31.636 1.00 38.45 ? 400 TYR A CG     1 
ATOM   5734 C CD1    . TYR B 2 400 ? 28.352 -17.386 30.707 1.00 38.15 ? 400 TYR A CD1    1 
ATOM   5735 C CD2    . TYR B 2 400 ? 29.557 -15.635 31.803 1.00 38.86 ? 400 TYR A CD2    1 
ATOM   5736 C CE1    . TYR B 2 400 ? 29.499 -17.705 29.972 1.00 38.23 ? 400 TYR A CE1    1 
ATOM   5737 C CE2    . TYR B 2 400 ? 30.698 -15.940 31.073 1.00 37.88 ? 400 TYR A CE2    1 
ATOM   5738 C CZ     . TYR B 2 400 ? 30.662 -16.976 30.168 1.00 38.91 ? 400 TYR A CZ     1 
ATOM   5739 O OH     . TYR B 2 400 ? 31.797 -17.309 29.482 1.00 41.76 ? 400 TYR A OH     1 
ATOM   5740 H H      . TYR B 2 400 ? 25.426 -14.746 33.746 1.00 20.00 ? 400 TYR A H      1 
ATOM   5741 H HH     . TYR B 2 400 ? 32.501 -16.703 29.729 1.00 20.00 ? 400 TYR A HH     1 
ATOM   5742 N N      . LYS B 2 401 ? 25.367 -15.262 29.498 1.00 42.17 ? 401 LYS A N      1 
ATOM   5743 C CA     . LYS B 2 401 ? 24.650 -15.900 28.388 1.00 40.87 ? 401 LYS A CA     1 
ATOM   5744 C C      . LYS B 2 401 ? 25.570 -16.478 27.320 1.00 40.41 ? 401 LYS A C      1 
ATOM   5745 O O      . LYS B 2 401 ? 25.207 -16.531 26.155 1.00 40.44 ? 401 LYS A O      1 
ATOM   5746 C CB     . LYS B 2 401 ? 23.604 -14.945 27.771 1.00 40.93 ? 401 LYS A CB     1 
ATOM   5747 C CG     . LYS B 2 401 ? 24.191 -13.747 26.999 1.00 43.85 ? 401 LYS A CG     1 
ATOM   5748 C CD     . LYS B 2 401 ? 23.251 -12.529 27.000 1.00 46.55 ? 401 LYS A CD     1 
ATOM   5749 C CE     . LYS B 2 401 ? 22.239 -12.558 25.857 1.00 47.39 ? 401 LYS A CE     1 
ATOM   5750 N NZ     . LYS B 2 401 ? 22.816 -12.152 24.546 1.00 50.15 ? 401 LYS A NZ     1 
ATOM   5751 H H      . LYS B 2 401 ? 25.810 -14.398 29.360 1.00 20.00 ? 401 LYS A H      1 
ATOM   5752 H HZ1    . LYS B 2 401 ? 23.720 -12.656 24.404 1.00 20.00 ? 401 LYS A HZ1    1 
ATOM   5753 H HZ2    . LYS B 2 401 ? 22.159 -12.426 23.782 1.00 20.00 ? 401 LYS A HZ2    1 
ATOM   5754 H HZ3    . LYS B 2 401 ? 22.977 -11.133 24.519 1.00 20.00 ? 401 LYS A HZ3    1 
ATOM   5755 N N      . ARG B 2 402 ? 26.757 -16.918 27.718 1.00 42.50 ? 402 ARG A N      1 
ATOM   5756 C CA     . ARG B 2 402 ? 27.690 -17.521 26.765 1.00 45.24 ? 402 ARG A CA     1 
ATOM   5757 C C      . ARG B 2 402 ? 27.939 -19.032 26.989 1.00 44.03 ? 402 ARG A C      1 
ATOM   5758 O O      . ARG B 2 402 ? 27.001 -19.758 27.324 1.00 42.60 ? 402 ARG A O      1 
ATOM   5759 C CB     . ARG B 2 402 ? 28.970 -16.692 26.697 1.00 51.10 ? 402 ARG A CB     1 
ATOM   5760 C CG     . ARG B 2 402 ? 28.747 -15.402 25.902 1.00 54.14 ? 402 ARG A CG     1 
ATOM   5761 C CD     . ARG B 2 402 ? 29.741 -14.302 26.222 1.00 55.90 ? 402 ARG A CD     1 
ATOM   5762 N NE     . ARG B 2 402 ? 29.489 -13.697 27.526 1.00 61.55 ? 402 ARG A NE     1 
ATOM   5763 C CZ     . ARG B 2 402 ? 30.445 -13.275 28.353 1.00 62.46 ? 402 ARG A CZ     1 
ATOM   5764 N NH1    . ARG B 2 402 ? 31.725 -13.398 28.016 1.00 66.38 ? 402 ARG A NH1    1 
ATOM   5765 N NH2    . ARG B 2 402 ? 30.123 -12.737 29.521 1.00 67.78 ? 402 ARG A NH2    1 
ATOM   5766 H H      . ARG B 2 402 ? 27.011 -16.832 28.652 1.00 20.00 ? 402 ARG A H      1 
ATOM   5767 H HE     . ARG B 2 402 ? 28.570 -13.619 27.799 1.00 20.00 ? 402 ARG A HE     1 
ATOM   5768 H HH11   . ARG B 2 402 ? 31.987 -13.826 27.145 1.00 20.00 ? 402 ARG A HH11   1 
ATOM   5769 H HH12   . ARG B 2 402 ? 32.444 -13.090 28.643 1.00 20.00 ? 402 ARG A HH12   1 
ATOM   5770 H HH21   . ARG B 2 402 ? 29.163 -12.661 29.774 1.00 20.00 ? 402 ARG A HH21   1 
ATOM   5771 H HH22   . ARG B 2 402 ? 30.841 -12.428 30.138 1.00 20.00 ? 402 ARG A HH22   1 
ATOM   5772 N N      . LEU B 2 403 ? 29.162 -19.527 26.818 1.00 44.76 ? 403 LEU A N      1 
ATOM   5773 C CA     . LEU B 2 403 ? 29.389 -20.970 26.990 1.00 42.23 ? 403 LEU A CA     1 
ATOM   5774 C C      . LEU B 2 403 ? 29.840 -21.501 28.337 1.00 45.38 ? 403 LEU A C      1 
ATOM   5775 O O      . LEU B 2 403 ? 31.038 -21.521 28.635 1.00 48.12 ? 403 LEU A O      1 
ATOM   5776 C CB     . LEU B 2 403 ? 30.336 -21.522 25.922 1.00 39.31 ? 403 LEU A CB     1 
ATOM   5777 C CG     . LEU B 2 403 ? 30.454 -23.048 25.906 1.00 37.63 ? 403 LEU A CG     1 
ATOM   5778 C CD1    . LEU B 2 403 ? 29.078 -23.660 25.718 1.00 36.95 ? 403 LEU A CD1    1 
ATOM   5779 C CD2    . LEU B 2 403 ? 31.397 -23.498 24.795 1.00 37.79 ? 403 LEU A CD2    1 
ATOM   5780 H H      . LEU B 2 403 ? 29.921 -18.943 26.603 1.00 20.00 ? 403 LEU A H      1 
ATOM   5781 N N      . VAL B 2 404 ? 28.884 -22.040 29.093 1.00 48.85 ? 404 VAL A N      1 
ATOM   5782 C CA     . VAL B 2 404 ? 29.160 -22.625 30.410 1.00 50.40 ? 404 VAL A CA     1 
ATOM   5783 C C      . VAL B 2 404 ? 29.382 -24.126 30.209 1.00 51.12 ? 404 VAL A C      1 
ATOM   5784 O O      . VAL B 2 404 ? 28.803 -24.710 29.291 1.00 49.55 ? 404 VAL A O      1 
ATOM   5785 C CB     . VAL B 2 404 ? 27.974 -22.442 31.385 1.00 51.85 ? 404 VAL A CB     1 
ATOM   5786 C CG1    . VAL B 2 404 ? 28.488 -22.008 32.753 1.00 53.46 ? 404 VAL A CG1    1 
ATOM   5787 C CG2    . VAL B 2 404 ? 26.953 -21.445 30.829 1.00 54.53 ? 404 VAL A CG2    1 
ATOM   5788 H H      . VAL B 2 404 ? 27.973 -22.063 28.736 1.00 20.00 ? 404 VAL A H      1 
ATOM   5789 N N      . LEU B 2 405 ? 30.144 -24.767 31.098 1.00 48.74 ? 405 LEU A N      1 
ATOM   5790 C CA     . LEU B 2 405 ? 30.430 -26.207 30.975 1.00 46.09 ? 405 LEU A CA     1 
ATOM   5791 C C      . LEU B 2 405 ? 29.241 -27.159 31.174 1.00 47.38 ? 405 LEU A C      1 
ATOM   5792 O O      . LEU B 2 405 ? 29.419 -28.320 31.512 1.00 46.65 ? 405 LEU A O      1 
ATOM   5793 C CB     . LEU B 2 405 ? 31.591 -26.608 31.896 1.00 41.33 ? 405 LEU A CB     1 
ATOM   5794 C CG     . LEU B 2 405 ? 32.171 -28.021 31.763 1.00 37.89 ? 405 LEU A CG     1 
ATOM   5795 C CD1    . LEU B 2 405 ? 32.514 -28.357 30.301 1.00 39.55 ? 405 LEU A CD1    1 
ATOM   5796 C CD2    . LEU B 2 405 ? 33.388 -28.144 32.657 1.00 37.37 ? 405 LEU A CD2    1 
ATOM   5797 H H      . LEU B 2 405 ? 30.522 -24.262 31.853 1.00 20.00 ? 405 LEU A H      1 
ATOM   5798 N N      . GLY B 2 406 ? 28.033 -26.679 30.932 1.00 50.13 ? 406 GLY A N      1 
ATOM   5799 C CA     . GLY B 2 406 ? 26.880 -27.533 31.094 1.00 52.27 ? 406 GLY A CA     1 
ATOM   5800 C C      . GLY B 2 406 ? 25.840 -27.358 30.005 1.00 54.49 ? 406 GLY A C      1 
ATOM   5801 O O      . GLY B 2 406 ? 25.087 -28.293 29.695 1.00 52.68 ? 406 GLY A O      1 
ATOM   5802 H H      . GLY B 2 406 ? 27.916 -25.788 30.617 1.00 20.00 ? 406 GLY A H      1 
ATOM   5803 N N      . LYS B 2 407 ? 25.770 -26.159 29.435 1.00 54.61 ? 407 LYS A N      1 
ATOM   5804 C CA     . LYS B 2 407 ? 24.793 -25.896 28.389 1.00 56.77 ? 407 LYS A CA     1 
ATOM   5805 C C      . LYS B 2 407 ? 25.319 -25.726 26.966 1.00 54.80 ? 407 LYS A C      1 
ATOM   5806 O O      . LYS B 2 407 ? 26.487 -26.004 26.664 1.00 52.42 ? 407 LYS A O      1 
ATOM   5807 C CB     . LYS B 2 407 ? 23.904 -24.711 28.760 1.00 60.53 ? 407 LYS A CB     1 
ATOM   5808 C CG     . LYS B 2 407 ? 22.832 -25.060 29.783 1.00 63.77 ? 407 LYS A CG     1 
ATOM   5809 C CD     . LYS B 2 407 ? 21.550 -24.285 29.520 1.00 65.05 ? 407 LYS A CD     1 
ATOM   5810 C CE     . LYS B 2 407 ? 21.043 -24.524 28.088 1.00 65.33 ? 407 LYS A CE     1 
ATOM   5811 N NZ     . LYS B 2 407 ? 19.709 -23.881 27.821 1.00 65.70 ? 407 LYS A NZ     1 
ATOM   5812 H H      . LYS B 2 407 ? 26.411 -25.478 29.682 1.00 20.00 ? 407 LYS A H      1 
ATOM   5813 H HZ1    . LYS B 2 407 ? 19.734 -22.891 28.177 1.00 20.00 ? 407 LYS A HZ1    1 
ATOM   5814 H HZ2    . LYS B 2 407 ? 19.521 -23.861 26.802 1.00 20.00 ? 407 LYS A HZ2    1 
ATOM   5815 H HZ3    . LYS B 2 407 ? 18.949 -24.388 28.313 1.00 20.00 ? 407 LYS A HZ3    1 
ATOM   5816 N N      . GLU B 2 408 ? 24.422 -25.283 26.094 1.00 53.38 ? 408 GLU A N      1 
ATOM   5817 C CA     . GLU B 2 408 ? 24.739 -25.062 24.695 1.00 51.69 ? 408 GLU A CA     1 
ATOM   5818 C C      . GLU B 2 408 ? 24.854 -23.570 24.359 1.00 48.79 ? 408 GLU A C      1 
ATOM   5819 O O      . GLU B 2 408 ? 24.270 -22.720 25.049 1.00 48.71 ? 408 GLU A O      1 
ATOM   5820 C CB     . GLU B 2 408 ? 23.643 -25.671 23.814 1.00 54.29 ? 408 GLU A CB     1 
ATOM   5821 C CG     . GLU B 2 408 ? 23.206 -27.065 24.209 1.00 55.62 ? 408 GLU A CG     1 
ATOM   5822 C CD     . GLU B 2 408 ? 22.328 -27.699 23.151 1.00 58.21 ? 408 GLU A CD     1 
ATOM   5823 O OE1    . GLU B 2 408 ? 22.888 -28.330 22.233 1.00 56.90 ? 408 GLU A OE1    1 
ATOM   5824 O OE2    . GLU B 2 408 ? 21.086 -27.556 23.228 1.00 61.23 ? 408 GLU A OE2    1 
ATOM   5825 H H      . GLU B 2 408 ? 23.526 -25.069 26.394 1.00 20.00 ? 408 GLU A H      1 
ATOM   5826 N N      . VAL B 2 409 ? 25.587 -23.275 23.281 1.00 47.33 ? 409 VAL A N      1 
ATOM   5827 C CA     . VAL B 2 409 ? 25.778 -21.905 22.787 1.00 44.14 ? 409 VAL A CA     1 
ATOM   5828 C C      . VAL B 2 409 ? 25.811 -21.899 21.270 1.00 42.16 ? 409 VAL A C      1 
ATOM   5829 O O      . VAL B 2 409 ? 26.472 -22.749 20.650 1.00 42.79 ? 409 VAL A O      1 
ATOM   5830 C CB     . VAL B 2 409 ? 27.098 -21.267 23.272 1.00 42.16 ? 409 VAL A CB     1 
ATOM   5831 C CG1    . VAL B 2 409 ? 27.081 -21.157 24.754 1.00 42.83 ? 409 VAL A CG1    1 
ATOM   5832 C CG2    . VAL B 2 409 ? 28.309 -22.068 22.786 1.00 41.44 ? 409 VAL A CG2    1 
ATOM   5833 H H      . VAL B 2 409 ? 26.011 -24.013 22.772 1.00 20.00 ? 409 VAL A H      1 
ATOM   5834 N N      . ARG B 2 410 ? 25.093 -20.960 20.670 1.00 41.40 ? 410 ARG A N      1 
ATOM   5835 C CA     . ARG B 2 410 ? 25.086 -20.869 19.220 1.00 42.72 ? 410 ARG A CA     1 
ATOM   5836 C C      . ARG B 2 410 ? 26.375 -20.232 18.703 1.00 41.21 ? 410 ARG A C      1 
ATOM   5837 O O      . ARG B 2 410 ? 26.860 -19.235 19.251 1.00 42.23 ? 410 ARG A O      1 
ATOM   5838 C CB     . ARG B 2 410 ? 23.878 -20.069 18.718 1.00 43.28 ? 410 ARG A CB     1 
ATOM   5839 C CG     . ARG B 2 410 ? 23.793 -19.989 17.193 1.00 46.52 ? 410 ARG A CG     1 
ATOM   5840 C CD     . ARG B 2 410 ? 23.966 -21.378 16.580 1.00 48.39 ? 410 ARG A CD     1 
ATOM   5841 N NE     . ARG B 2 410 ? 22.880 -21.806 15.696 1.00 49.15 ? 410 ARG A NE     1 
ATOM   5842 C CZ     . ARG B 2 410 ? 21.578 -21.636 15.936 1.00 52.02 ? 410 ARG A CZ     1 
ATOM   5843 N NH1    . ARG B 2 410 ? 21.155 -20.999 17.025 1.00 48.51 ? 410 ARG A NH1    1 
ATOM   5844 N NH2    . ARG B 2 410 ? 20.688 -22.086 15.061 1.00 52.22 ? 410 ARG A NH2    1 
ATOM   5845 H H      . ARG B 2 410 ? 24.617 -20.287 21.209 1.00 20.00 ? 410 ARG A H      1 
ATOM   5846 H HE     . ARG B 2 410 ? 23.115 -22.235 14.857 1.00 20.00 ? 410 ARG A HE     1 
ATOM   5847 H HH11   . ARG B 2 410 ? 21.786 -20.659 17.704 1.00 20.00 ? 410 ARG A HH11   1 
ATOM   5848 H HH12   . ARG B 2 410 ? 20.166 -20.905 17.200 1.00 20.00 ? 410 ARG A HH12   1 
ATOM   5849 H HH21   . ARG B 2 410 ? 20.990 -22.542 14.230 1.00 20.00 ? 410 ARG A HH21   1 
ATOM   5850 H HH22   . ARG B 2 410 ? 19.705 -21.970 15.242 1.00 20.00 ? 410 ARG A HH22   1 
ATOM   5851 N N      . LEU B 2 411 ? 26.983 -20.875 17.716 1.00 36.21 ? 411 LEU A N      1 
ATOM   5852 C CA     . LEU B 2 411 ? 28.173 -20.312 17.100 1.00 33.26 ? 411 LEU A CA     1 
ATOM   5853 C C      . LEU B 2 411 ? 27.638 -19.276 16.082 1.00 31.35 ? 411 LEU A C      1 
ATOM   5854 O O      . LEU B 2 411 ? 26.490 -19.371 15.619 1.00 33.39 ? 411 LEU A O      1 
ATOM   5855 C CB     . LEU B 2 411 ? 29.011 -21.406 16.429 1.00 32.84 ? 411 LEU A CB     1 
ATOM   5856 C CG     . LEU B 2 411 ? 29.527 -22.474 17.394 1.00 28.85 ? 411 LEU A CG     1 
ATOM   5857 C CD1    . LEU B 2 411 ? 30.836 -23.055 16.894 1.00 29.61 ? 411 LEU A CD1    1 
ATOM   5858 C CD2    . LEU B 2 411 ? 29.746 -21.845 18.744 1.00 31.20 ? 411 LEU A CD2    1 
ATOM   5859 H H      . LEU B 2 411 ? 26.633 -21.740 17.410 1.00 20.00 ? 411 LEU A H      1 
ATOM   5860 N N      . ARG B 2 412 ? 28.427 -18.262 15.767 1.00 30.10 ? 412 ARG A N      1 
ATOM   5861 C CA     . ARG B 2 412 ? 27.937 -17.253 14.851 1.00 28.98 ? 412 ARG A CA     1 
ATOM   5862 C C      . ARG B 2 412 ? 27.630 -17.864 13.502 1.00 30.90 ? 412 ARG A C      1 
ATOM   5863 O O      . ARG B 2 412 ? 28.510 -18.460 12.869 1.00 32.06 ? 412 ARG A O      1 
ATOM   5864 C CB     . ARG B 2 412 ? 28.927 -16.095 14.710 1.00 26.69 ? 412 ARG A CB     1 
ATOM   5865 C CG     . ARG B 2 412 ? 28.316 -14.729 15.028 1.00 22.05 ? 412 ARG A CG     1 
ATOM   5866 C CD     . ARG B 2 412 ? 27.184 -14.395 14.076 1.00 17.59 ? 412 ARG A CD     1 
ATOM   5867 N NE     . ARG B 2 412 ? 26.140 -13.615 14.717 1.00 15.46 ? 412 ARG A NE     1 
ATOM   5868 C CZ     . ARG B 2 412 ? 25.338 -12.758 14.090 1.00 13.12 ? 412 ARG A CZ     1 
ATOM   5869 N NH1    . ARG B 2 412 ? 25.463 -12.529 12.782 1.00 12.96 ? 412 ARG A NH1    1 
ATOM   5870 N NH2    . ARG B 2 412 ? 24.406 -12.115 14.781 1.00 13.20 ? 412 ARG A NH2    1 
ATOM   5871 H H      . ARG B 2 412 ? 29.312 -18.189 16.161 1.00 20.00 ? 412 ARG A H      1 
ATOM   5872 H HE     . ARG B 2 412 ? 25.999 -13.775 15.668 1.00 20.00 ? 412 ARG A HE     1 
ATOM   5873 H HH11   . ARG B 2 412 ? 26.176 -13.002 12.256 1.00 20.00 ? 412 ARG A HH11   1 
ATOM   5874 H HH12   . ARG B 2 412 ? 24.856 -11.884 12.327 1.00 20.00 ? 412 ARG A HH12   1 
ATOM   5875 H HH21   . ARG B 2 412 ? 24.273 -12.326 15.747 1.00 20.00 ? 412 ARG A HH21   1 
ATOM   5876 H HH22   . ARG B 2 412 ? 23.779 -11.502 14.306 1.00 20.00 ? 412 ARG A HH22   1 
ATOM   5877 N N      . ASN B 2 413 ? 26.356 -17.751 13.120 1.00 34.43 ? 413 ASN A N      1 
ATOM   5878 C CA     . ASN B 2 413 ? 25.841 -18.254 11.847 1.00 38.34 ? 413 ASN A CA     1 
ATOM   5879 C C      . ASN B 2 413 ? 26.118 -19.737 11.595 1.00 40.23 ? 413 ASN A C      1 
ATOM   5880 O O      . ASN B 2 413 ? 26.112 -20.186 10.444 1.00 38.75 ? 413 ASN A O      1 
ATOM   5881 C CB     . ASN B 2 413 ? 26.406 -17.450 10.682 1.00 40.65 ? 413 ASN A CB     1 
ATOM   5882 C CG     . ASN B 2 413 ? 26.113 -15.984 10.799 1.00 42.41 ? 413 ASN A CG     1 
ATOM   5883 O OD1    . ASN B 2 413 ? 27.014 -15.158 10.634 1.00 42.09 ? 413 ASN A OD1    1 
ATOM   5884 N ND2    . ASN B 2 413 ? 24.850 -15.637 11.069 1.00 42.77 ? 413 ASN A ND2    1 
ATOM   5885 H H      . ASN B 2 413 ? 25.720 -17.340 13.758 1.00 20.00 ? 413 ASN A H      1 
ATOM   5886 H HD21   . ASN B 2 413 ? 24.674 -14.670 11.132 1.00 20.00 ? 413 ASN A HD21   1 
ATOM   5887 H HD22   . ASN B 2 413 ? 24.185 -16.324 11.168 1.00 20.00 ? 413 ASN A HD22   1 
ATOM   5888 N N      . ALA B 2 414 ? 26.364 -20.506 12.650 1.00 41.87 ? 414 ALA A N      1 
ATOM   5889 C CA     . ALA B 2 414 ? 26.636 -21.927 12.467 1.00 43.52 ? 414 ALA A CA     1 
ATOM   5890 C C      . ALA B 2 414 ? 25.805 -22.839 13.373 1.00 44.64 ? 414 ALA A C      1 
ATOM   5891 O O      . ALA B 2 414 ? 24.580 -22.661 13.497 1.00 45.03 ? 414 ALA A O      1 
ATOM   5892 C CB     . ALA B 2 414 ? 28.132 -22.213 12.617 1.00 42.87 ? 414 ALA A CB     1 
ATOM   5893 H H      . ALA B 2 414 ? 26.356 -20.121 13.553 1.00 20.00 ? 414 ALA A H      1 
ATOM   5894 N N      . TYR B 2 415 ? 26.478 -23.783 14.026 1.00 44.58 ? 415 TYR A N      1 
ATOM   5895 C CA     . TYR B 2 415 ? 25.820 -24.767 14.877 1.00 43.11 ? 415 TYR A CA     1 
ATOM   5896 C C      . TYR B 2 415 ? 25.699 -24.473 16.360 1.00 41.82 ? 415 TYR A C      1 
ATOM   5897 O O      . TYR B 2 415 ? 26.561 -23.790 16.935 1.00 41.79 ? 415 TYR A O      1 
ATOM   5898 C CB     . TYR B 2 415 ? 26.516 -26.108 14.732 1.00 43.02 ? 415 TYR A CB     1 
ATOM   5899 C CG     . TYR B 2 415 ? 26.558 -26.584 13.312 1.00 42.80 ? 415 TYR A CG     1 
ATOM   5900 C CD1    . TYR B 2 415 ? 25.390 -27.006 12.666 1.00 42.83 ? 415 TYR A CD1    1 
ATOM   5901 C CD2    . TYR B 2 415 ? 27.764 -26.612 12.601 1.00 41.47 ? 415 TYR A CD2    1 
ATOM   5902 C CE1    . TYR B 2 415 ? 25.426 -27.446 11.350 1.00 43.03 ? 415 TYR A CE1    1 
ATOM   5903 C CE2    . TYR B 2 415 ? 27.809 -27.052 11.281 1.00 41.11 ? 415 TYR A CE2    1 
ATOM   5904 C CZ     . TYR B 2 415 ? 26.636 -27.469 10.663 1.00 40.34 ? 415 TYR A CZ     1 
ATOM   5905 O OH     . TYR B 2 415 ? 26.656 -27.912 9.368  1.00 41.03 ? 415 TYR A OH     1 
ATOM   5906 H H      . TYR B 2 415 ? 27.439 -23.819 13.974 1.00 20.00 ? 415 TYR A H      1 
ATOM   5907 H HH     . TYR B 2 415 ? 27.515 -27.839 9.052  1.00 20.00 ? 415 TYR A HH     1 
ATOM   5908 N N      . VAL B 2 416 ? 24.641 -25.024 16.974 1.00 38.88 ? 416 VAL A N      1 
ATOM   5909 C CA     . VAL B 2 416 ? 24.383 -24.896 18.413 1.00 34.11 ? 416 VAL A CA     1 
ATOM   5910 C C      . VAL B 2 416 ? 25.205 -25.973 19.099 1.00 35.79 ? 416 VAL A C      1 
ATOM   5911 O O      . VAL B 2 416 ? 24.796 -27.124 19.136 1.00 36.37 ? 416 VAL A O      1 
ATOM   5912 C CB     . VAL B 2 416 ? 22.918 -25.167 18.776 1.00 29.77 ? 416 VAL A CB     1 
ATOM   5913 C CG1    . VAL B 2 416 ? 22.774 -25.269 20.266 1.00 26.22 ? 416 VAL A CG1    1 
ATOM   5914 C CG2    . VAL B 2 416 ? 22.038 -24.074 18.256 1.00 28.27 ? 416 VAL A CG2    1 
ATOM   5915 H H      . VAL B 2 416 ? 24.020 -25.495 16.428 1.00 20.00 ? 416 VAL A H      1 
ATOM   5916 N N      . ILE B 2 417 ? 26.404 -25.631 19.547 1.00 39.13 ? 417 ILE A N      1 
ATOM   5917 C CA     . ILE B 2 417 ? 27.242 -26.615 20.222 1.00 43.00 ? 417 ILE A CA     1 
ATOM   5918 C C      . ILE B 2 417 ? 26.815 -26.745 21.673 1.00 45.84 ? 417 ILE A C      1 
ATOM   5919 O O      . ILE B 2 417 ? 25.969 -25.975 22.152 1.00 45.21 ? 417 ILE A O      1 
ATOM   5920 C CB     . ILE B 2 417 ? 28.745 -26.255 20.158 1.00 42.59 ? 417 ILE A CB     1 
ATOM   5921 C CG1    . ILE B 2 417 ? 28.995 -24.846 20.719 1.00 41.85 ? 417 ILE A CG1    1 
ATOM   5922 C CG2    . ILE B 2 417 ? 29.242 -26.407 18.730 1.00 41.94 ? 417 ILE A CG2    1 
ATOM   5923 C CD1    . ILE B 2 417 ? 30.463 -24.517 20.891 1.00 41.88 ? 417 ILE A CD1    1 
ATOM   5924 H H      . ILE B 2 417 ? 26.704 -24.692 19.455 1.00 20.00 ? 417 ILE A H      1 
ATOM   5925 N N      . LYS B 2 418 ? 27.419 -27.707 22.367 1.00 47.78 ? 418 LYS A N      1 
ATOM   5926 C CA     . LYS B 2 418 ? 27.117 -27.965 23.769 1.00 49.38 ? 418 LYS A CA     1 
ATOM   5927 C C      . LYS B 2 418 ? 28.386 -28.350 24.528 1.00 52.11 ? 418 LYS A C      1 
ATOM   5928 O O      . LYS B 2 418 ? 29.084 -29.296 24.148 1.00 53.45 ? 418 LYS A O      1 
ATOM   5929 C CB     . LYS B 2 418 ? 26.077 -29.077 23.896 1.00 49.12 ? 418 LYS A CB     1 
ATOM   5930 C CG     . LYS B 2 418 ? 25.533 -29.238 25.299 1.00 50.31 ? 418 LYS A CG     1 
ATOM   5931 C CD     . LYS B 2 418 ? 25.629 -30.685 25.762 1.00 53.95 ? 418 LYS A CD     1 
ATOM   5932 C CE     . LYS B 2 418 ? 24.635 -31.613 25.046 1.00 55.62 ? 418 LYS A CE     1 
ATOM   5933 N NZ     . LYS B 2 418 ? 24.900 -33.064 25.324 1.00 56.96 ? 418 LYS A NZ     1 
ATOM   5934 H H      . LYS B 2 418 ? 28.092 -28.252 21.920 1.00 20.00 ? 418 LYS A H      1 
ATOM   5935 H HZ1    . LYS B 2 418 ? 25.057 -33.184 26.350 1.00 20.00 ? 418 LYS A HZ1    1 
ATOM   5936 H HZ2    . LYS B 2 418 ? 24.085 -33.622 25.026 1.00 20.00 ? 418 LYS A HZ2    1 
ATOM   5937 H HZ3    . LYS B 2 418 ? 25.753 -33.372 24.814 1.00 20.00 ? 418 LYS A HZ3    1 
ATOM   5938 N N      . ALA B 2 419 ? 28.682 -27.595 25.585 1.00 55.35 ? 419 ALA A N      1 
ATOM   5939 C CA     . ALA B 2 419 ? 29.862 -27.828 26.412 1.00 56.11 ? 419 ALA A CA     1 
ATOM   5940 C C      . ALA B 2 419 ? 29.784 -29.160 27.155 1.00 57.05 ? 419 ALA A C      1 
ATOM   5941 O O      . ALA B 2 419 ? 28.735 -29.518 27.708 1.00 54.76 ? 419 ALA A O      1 
ATOM   5942 C CB     . ALA B 2 419 ? 30.038 -26.697 27.395 1.00 56.09 ? 419 ALA A CB     1 
ATOM   5943 H H      . ALA B 2 419 ? 28.063 -26.878 25.848 1.00 20.00 ? 419 ALA A H      1 
ATOM   5944 N N      . GLU B 2 420 ? 30.914 -29.865 27.206 1.00 60.05 ? 420 GLU A N      1 
ATOM   5945 C CA     . GLU B 2 420 ? 30.947 -31.162 27.861 1.00 59.92 ? 420 GLU A CA     1 
ATOM   5946 C C      . GLU B 2 420 ? 32.196 -31.476 28.676 1.00 56.53 ? 420 GLU A C      1 
ATOM   5947 O O      . GLU B 2 420 ? 32.116 -31.656 29.886 1.00 54.69 ? 420 GLU A O      1 
ATOM   5948 C CB     . GLU B 2 420 ? 30.753 -32.267 26.813 1.00 63.34 ? 420 GLU A CB     1 
ATOM   5949 C CG     . GLU B 2 420 ? 29.673 -33.280 27.158 1.00 66.18 ? 420 GLU A CG     1 
ATOM   5950 C CD     . GLU B 2 420 ? 28.272 -32.732 26.959 1.00 63.33 ? 420 GLU A CD     1 
ATOM   5951 O OE1    . GLU B 2 420 ? 27.779 -32.799 25.818 1.00 63.48 ? 420 GLU A OE1    1 
ATOM   5952 O OE2    . GLU B 2 420 ? 27.662 -32.237 27.935 1.00 61.81 ? 420 GLU A OE2    1 
ATOM   5953 H H      . GLU B 2 420 ? 31.737 -29.508 26.802 1.00 20.00 ? 420 GLU A H      1 
ATOM   5954 N N      . ARG B 2 421 ? 33.344 -31.534 28.011 1.00 54.09 ? 421 ARG A N      1 
ATOM   5955 C CA     . ARG B 2 421 ? 34.586 -31.899 28.681 1.00 51.52 ? 421 ARG A CA     1 
ATOM   5956 C C      . ARG B 2 421 ? 35.727 -30.919 28.429 1.00 48.22 ? 421 ARG A C      1 
ATOM   5957 O O      . ARG B 2 421 ? 36.110 -30.680 27.283 1.00 47.05 ? 421 ARG A O      1 
ATOM   5958 C CB     . ARG B 2 421 ? 34.991 -33.311 28.222 1.00 54.20 ? 421 ARG A CB     1 
ATOM   5959 C CG     . ARG B 2 421 ? 36.074 -33.988 29.052 1.00 52.76 ? 421 ARG A CG     1 
ATOM   5960 C CD     . ARG B 2 421 ? 37.439 -34.029 28.350 1.00 51.80 ? 421 ARG A CD     1 
ATOM   5961 N NE     . ARG B 2 421 ? 37.420 -34.794 27.095 1.00 50.65 ? 421 ARG A NE     1 
ATOM   5962 C CZ     . ARG B 2 421 ? 38.512 -35.154 26.420 1.00 51.23 ? 421 ARG A CZ     1 
ATOM   5963 N NH1    . ARG B 2 421 ? 39.721 -34.836 26.878 1.00 51.05 ? 421 ARG A NH1    1 
ATOM   5964 N NH2    . ARG B 2 421 ? 38.399 -35.838 25.292 1.00 47.84 ? 421 ARG A NH2    1 
ATOM   5965 H H      . ARG B 2 421 ? 33.377 -31.313 27.053 1.00 20.00 ? 421 ARG A H      1 
ATOM   5966 H HE     . ARG B 2 421 ? 36.545 -35.067 26.733 1.00 20.00 ? 421 ARG A HE     1 
ATOM   5967 H HH11   . ARG B 2 421 ? 39.801 -34.328 27.743 1.00 20.00 ? 421 ARG A HH11   1 
ATOM   5968 H HH12   . ARG B 2 421 ? 40.534 -35.093 26.376 1.00 20.00 ? 421 ARG A HH12   1 
ATOM   5969 H HH21   . ARG B 2 421 ? 37.493 -36.079 24.943 1.00 20.00 ? 421 ARG A HH21   1 
ATOM   5970 H HH22   . ARG B 2 421 ? 39.218 -36.091 24.782 1.00 20.00 ? 421 ARG A HH22   1 
ATOM   5971 N N      . VAL B 2 422 ? 36.231 -30.327 29.503 1.00 44.43 ? 422 VAL A N      1 
ATOM   5972 C CA     . VAL B 2 422 ? 37.338 -29.382 29.426 1.00 41.99 ? 422 VAL A CA     1 
ATOM   5973 C C      . VAL B 2 422 ? 38.637 -30.167 29.564 1.00 43.30 ? 422 VAL A C      1 
ATOM   5974 O O      . VAL B 2 422 ? 38.618 -31.369 29.791 1.00 43.04 ? 422 VAL A O      1 
ATOM   5975 C CB     . VAL B 2 422 ? 37.232 -28.340 30.563 1.00 38.90 ? 422 VAL A CB     1 
ATOM   5976 C CG1    . VAL B 2 422 ? 38.447 -27.409 30.612 1.00 39.96 ? 422 VAL A CG1    1 
ATOM   5977 C CG2    . VAL B 2 422 ? 35.960 -27.537 30.388 1.00 39.06 ? 422 VAL A CG2    1 
ATOM   5978 H H      . VAL B 2 422 ? 35.857 -30.541 30.369 1.00 20.00 ? 422 VAL A H      1 
ATOM   5979 N N      . GLU B 2 423 ? 39.759 -29.491 29.397 1.00 43.43 ? 423 GLU A N      1 
ATOM   5980 C CA     . GLU B 2 423 ? 41.067 -30.104 29.537 1.00 45.93 ? 423 GLU A CA     1 
ATOM   5981 C C      . GLU B 2 423 ? 41.932 -28.967 30.036 1.00 42.29 ? 423 GLU A C      1 
ATOM   5982 O O      . GLU B 2 423 ? 41.965 -27.901 29.424 1.00 42.47 ? 423 GLU A O      1 
ATOM   5983 C CB     . GLU B 2 423 ? 41.580 -30.605 28.188 1.00 52.92 ? 423 GLU A CB     1 
ATOM   5984 C CG     . GLU B 2 423 ? 42.979 -31.192 28.251 1.00 57.42 ? 423 GLU A CG     1 
ATOM   5985 C CD     . GLU B 2 423 ? 43.381 -31.905 26.955 1.00 60.70 ? 423 GLU A CD     1 
ATOM   5986 O OE1    . GLU B 2 423 ? 42.650 -32.833 26.523 1.00 59.91 ? 423 GLU A OE1    1 
ATOM   5987 O OE2    . GLU B 2 423 ? 44.428 -31.547 26.368 1.00 59.69 ? 423 GLU A OE2    1 
ATOM   5988 H H      . GLU B 2 423 ? 39.729 -28.551 29.114 1.00 20.00 ? 423 GLU A H      1 
ATOM   5989 N N      . LYS B 2 424 ? 42.589 -29.154 31.168 1.00 41.33 ? 424 LYS A N      1 
ATOM   5990 C CA     . LYS B 2 424 ? 43.389 -28.068 31.697 1.00 39.08 ? 424 LYS A CA     1 
ATOM   5991 C C      . LYS B 2 424 ? 44.884 -28.077 31.483 1.00 40.87 ? 424 LYS A C      1 
ATOM   5992 O O      . LYS B 2 424 ? 45.517 -29.102 31.254 1.00 40.31 ? 424 LYS A O      1 
ATOM   5993 C CB     . LYS B 2 424 ? 43.082 -27.814 33.177 1.00 34.68 ? 424 LYS A CB     1 
ATOM   5994 C CG     . LYS B 2 424 ? 41.733 -27.112 33.420 1.00 31.86 ? 424 LYS A CG     1 
ATOM   5995 C CD     . LYS B 2 424 ? 41.646 -26.521 34.826 1.00 29.49 ? 424 LYS A CD     1 
ATOM   5996 C CE     . LYS B 2 424 ? 40.317 -25.820 35.090 1.00 28.44 ? 424 LYS A CE     1 
ATOM   5997 N NZ     . LYS B 2 424 ? 39.159 -26.750 34.960 1.00 27.14 ? 424 LYS A NZ     1 
ATOM   5998 H H      . LYS B 2 424 ? 42.549 -30.004 31.626 1.00 20.00 ? 424 LYS A H      1 
ATOM   5999 H HZ1    . LYS B 2 424 ? 39.360 -27.631 35.455 1.00 20.00 ? 424 LYS A HZ1    1 
ATOM   6000 H HZ2    . LYS B 2 424 ? 38.315 -26.304 35.364 1.00 20.00 ? 424 LYS A HZ2    1 
ATOM   6001 H HZ3    . LYS B 2 424 ? 38.978 -26.949 33.947 1.00 20.00 ? 424 LYS A HZ3    1 
ATOM   6002 N N      . ASP B 2 425 ? 45.409 -26.866 31.450 1.00 44.85 ? 425 ASP A N      1 
ATOM   6003 C CA     . ASP B 2 425 ? 46.814 -26.600 31.334 1.00 46.97 ? 425 ASP A CA     1 
ATOM   6004 C C      . ASP B 2 425 ? 47.272 -26.848 32.768 1.00 48.20 ? 425 ASP A C      1 
ATOM   6005 O O      . ASP B 2 425 ? 46.516 -26.594 33.719 1.00 49.64 ? 425 ASP A O      1 
ATOM   6006 C CB     . ASP B 2 425 ? 47.004 -25.127 30.910 1.00 48.83 ? 425 ASP A CB     1 
ATOM   6007 C CG     . ASP B 2 425 ? 48.254 -24.478 31.509 1.00 47.83 ? 425 ASP A CG     1 
ATOM   6008 O OD1    . ASP B 2 425 ? 49.338 -24.527 30.874 1.00 47.70 ? 425 ASP A OD1    1 
ATOM   6009 O OD2    . ASP B 2 425 ? 48.138 -23.887 32.602 1.00 51.03 ? 425 ASP A OD2    1 
ATOM   6010 H H      . ASP B 2 425 ? 44.834 -26.135 31.466 1.00 20.00 ? 425 ASP A H      1 
ATOM   6011 N N      . ALA B 2 426 ? 48.490 -27.356 32.923 1.00 49.06 ? 426 ALA A N      1 
ATOM   6012 C CA     . ALA B 2 426 ? 49.053 -27.646 34.247 1.00 48.31 ? 426 ALA A CA     1 
ATOM   6013 C C      . ALA B 2 426 ? 48.784 -26.560 35.289 1.00 47.33 ? 426 ALA A C      1 
ATOM   6014 O O      . ALA B 2 426 ? 48.437 -26.859 36.427 1.00 48.08 ? 426 ALA A O      1 
ATOM   6015 C CB     . ALA B 2 426 ? 50.565 -27.897 34.132 1.00 50.72 ? 426 ALA A CB     1 
ATOM   6016 H H      . ALA B 2 426 ? 49.020 -27.562 32.131 1.00 20.00 ? 426 ALA A H      1 
ATOM   6017 N N      . GLU B 2 427 ? 48.929 -25.304 34.884 1.00 48.51 ? 427 GLU A N      1 
ATOM   6018 C CA     . GLU B 2 427 ? 48.725 -24.184 35.784 1.00 47.53 ? 427 GLU A CA     1 
ATOM   6019 C C      . GLU B 2 427 ? 47.256 -23.767 35.902 1.00 46.09 ? 427 GLU A C      1 
ATOM   6020 O O      . GLU B 2 427 ? 46.932 -22.583 35.785 1.00 44.99 ? 427 GLU A O      1 
ATOM   6021 C CB     . GLU B 2 427 ? 49.570 -23.002 35.323 1.00 50.53 ? 427 GLU A CB     1 
ATOM   6022 C CG     . GLU B 2 427 ? 51.070 -23.232 35.422 1.00 49.53 ? 427 GLU A CG     1 
ATOM   6023 C CD     . GLU B 2 427 ? 51.566 -24.467 34.674 1.00 47.74 ? 427 GLU A CD     1 
ATOM   6024 O OE1    . GLU B 2 427 ? 51.405 -24.556 33.434 1.00 47.34 ? 427 GLU A OE1    1 
ATOM   6025 O OE2    . GLU B 2 427 ? 52.136 -25.354 35.340 1.00 45.65 ? 427 GLU A OE2    1 
ATOM   6026 H H      . GLU B 2 427 ? 49.162 -25.137 33.959 1.00 20.00 ? 427 GLU A H      1 
ATOM   6027 N N      . GLY B 2 428 ? 46.372 -24.752 36.071 1.00 46.08 ? 428 GLY A N      1 
ATOM   6028 C CA     . GLY B 2 428 ? 44.945 -24.492 36.224 1.00 46.45 ? 428 GLY A CA     1 
ATOM   6029 C C      . GLY B 2 428 ? 44.230 -23.813 35.065 1.00 48.01 ? 428 GLY A C      1 
ATOM   6030 O O      . GLY B 2 428 ? 43.034 -23.507 35.169 1.00 48.63 ? 428 GLY A O      1 
ATOM   6031 H H      . GLY B 2 428 ? 46.680 -25.681 36.090 1.00 20.00 ? 428 GLY A H      1 
ATOM   6032 N N      . ASN B 2 429 ? 44.953 -23.567 33.970 1.00 50.91 ? 429 ASN A N      1 
ATOM   6033 C CA     . ASN B 2 429 ? 44.378 -22.918 32.789 1.00 51.09 ? 429 ASN A CA     1 
ATOM   6034 C C      . ASN B 2 429 ? 43.645 -23.932 31.926 1.00 48.81 ? 429 ASN A C      1 
ATOM   6035 O O      . ASN B 2 429 ? 43.656 -25.114 32.223 1.00 51.28 ? 429 ASN A O      1 
ATOM   6036 C CB     . ASN B 2 429 ? 45.474 -22.255 31.970 1.00 53.55 ? 429 ASN A CB     1 
ATOM   6037 C CG     . ASN B 2 429 ? 46.255 -21.254 32.767 1.00 54.91 ? 429 ASN A CG     1 
ATOM   6038 O OD1    . ASN B 2 429 ? 47.480 -21.217 32.684 1.00 56.06 ? 429 ASN A OD1    1 
ATOM   6039 N ND2    . ASN B 2 429 ? 45.558 -20.430 33.544 1.00 57.48 ? 429 ASN A ND2    1 
ATOM   6040 H H      . ASN B 2 429 ? 45.890 -23.811 33.965 1.00 20.00 ? 429 ASN A H      1 
ATOM   6041 H HD21   . ASN B 2 429 ? 46.065 -19.770 34.066 1.00 20.00 ? 429 ASN A HD21   1 
ATOM   6042 H HD22   . ASN B 2 429 ? 44.586 -20.489 33.573 1.00 20.00 ? 429 ASN A HD22   1 
ATOM   6043 N N      . ILE B 2 430 ? 43.005 -23.479 30.857 1.00 45.86 ? 430 ILE A N      1 
ATOM   6044 C CA     . ILE B 2 430 ? 42.286 -24.387 29.972 1.00 42.33 ? 430 ILE A CA     1 
ATOM   6045 C C      . ILE B 2 430 ? 43.069 -24.552 28.674 1.00 41.45 ? 430 ILE A C      1 
ATOM   6046 O O      . ILE B 2 430 ? 43.328 -23.566 27.989 1.00 40.72 ? 430 ILE A O      1 
ATOM   6047 C CB     . ILE B 2 430 ? 40.906 -23.837 29.609 1.00 40.37 ? 430 ILE A CB     1 
ATOM   6048 C CG1    . ILE B 2 430 ? 40.136 -23.445 30.870 1.00 39.58 ? 430 ILE A CG1    1 
ATOM   6049 C CG2    . ILE B 2 430 ? 40.146 -24.861 28.781 1.00 40.19 ? 430 ILE A CG2    1 
ATOM   6050 C CD1    . ILE B 2 430 ? 40.600 -22.133 31.497 1.00 40.43 ? 430 ILE A CD1    1 
ATOM   6051 H H      . ILE B 2 430 ? 43.007 -22.524 30.657 1.00 20.00 ? 430 ILE A H      1 
ATOM   6052 N N      . THR B 2 431 ? 43.479 -25.777 28.354 1.00 40.01 ? 431 THR A N      1 
ATOM   6053 C CA     . THR B 2 431 ? 44.211 -26.023 27.114 1.00 38.28 ? 431 THR A CA     1 
ATOM   6054 C C      . THR B 2 431 ? 43.243 -26.138 25.960 1.00 37.30 ? 431 THR A C      1 
ATOM   6055 O O      . THR B 2 431 ? 43.549 -25.725 24.845 1.00 38.99 ? 431 THR A O      1 
ATOM   6056 C CB     . THR B 2 431 ? 45.040 -27.316 27.145 1.00 39.88 ? 431 THR A CB     1 
ATOM   6057 O OG1    . THR B 2 431 ? 44.392 -28.304 27.971 1.00 41.78 ? 431 THR A OG1    1 
ATOM   6058 C CG2    . THR B 2 431 ? 46.433 -27.030 27.649 1.00 37.84 ? 431 THR A CG2    1 
ATOM   6059 H H      . THR B 2 431 ? 43.277 -26.527 28.953 1.00 20.00 ? 431 THR A H      1 
ATOM   6060 H HG1    . THR B 2 431 ? 44.904 -29.118 27.986 1.00 20.00 ? 431 THR A HG1    1 
ATOM   6061 N N      . THR B 2 432 ? 42.081 -26.723 26.217 1.00 35.79 ? 432 THR A N      1 
ATOM   6062 C CA     . THR B 2 432 ? 41.089 -26.892 25.172 1.00 34.42 ? 432 THR A CA     1 
ATOM   6063 C C      . THR B 2 432 ? 39.732 -27.229 25.723 1.00 36.85 ? 432 THR A C      1 
ATOM   6064 O O      . THR B 2 432 ? 39.610 -27.649 26.866 1.00 35.35 ? 432 THR A O      1 
ATOM   6065 C CB     . THR B 2 432 ? 41.478 -28.028 24.194 1.00 32.37 ? 432 THR A CB     1 
ATOM   6066 O OG1    . THR B 2 432 ? 40.291 -28.705 23.746 1.00 33.56 ? 432 THR A OG1    1 
ATOM   6067 C CG2    . THR B 2 432 ? 42.397 -29.033 24.855 1.00 31.09 ? 432 THR A CG2    1 
ATOM   6068 H H      . THR B 2 432 ? 41.874 -27.039 27.127 1.00 20.00 ? 432 THR A H      1 
ATOM   6069 H HG1    . THR B 2 432 ? 40.502 -29.404 23.134 1.00 20.00 ? 432 THR A HG1    1 
ATOM   6070 N N      . ILE B 2 433 ? 38.724 -27.076 24.876 1.00 35.61 ? 433 ILE A N      1 
ATOM   6071 C CA     . ILE B 2 433 ? 37.364 -27.392 25.243 1.00 38.04 ? 433 ILE A CA     1 
ATOM   6072 C C      . ILE B 2 433 ? 36.817 -28.425 24.250 1.00 39.98 ? 433 ILE A C      1 
ATOM   6073 O O      . ILE B 2 433 ? 37.127 -28.384 23.049 1.00 40.47 ? 433 ILE A O      1 
ATOM   6074 C CB     . ILE B 2 433 ? 36.493 -26.123 25.268 1.00 40.06 ? 433 ILE A CB     1 
ATOM   6075 C CG1    . ILE B 2 433 ? 37.153 -25.082 26.186 1.00 40.96 ? 433 ILE A CG1    1 
ATOM   6076 C CG2    . ILE B 2 433 ? 35.068 -26.449 25.744 1.00 40.05 ? 433 ILE A CG2    1 
ATOM   6077 C CD1    . ILE B 2 433 ? 36.397 -23.784 26.304 1.00 41.35 ? 433 ILE A CD1    1 
ATOM   6078 H H      . ILE B 2 433 ? 38.911 -26.759 23.964 1.00 20.00 ? 433 ILE A H      1 
ATOM   6079 N N      . PHE B 2 434 ? 36.099 -29.409 24.781 1.00 39.02 ? 434 PHE A N      1 
ATOM   6080 C CA     . PHE B 2 434 ? 35.491 -30.457 23.981 1.00 38.23 ? 434 PHE A CA     1 
ATOM   6081 C C      . PHE B 2 434 ? 33.998 -30.280 24.161 1.00 42.73 ? 434 PHE A C      1 
ATOM   6082 O O      . PHE B 2 434 ? 33.507 -30.156 25.294 1.00 42.86 ? 434 PHE A O      1 
ATOM   6083 C CB     . PHE B 2 434 ? 35.928 -31.835 24.465 1.00 31.55 ? 434 PHE A CB     1 
ATOM   6084 C CG     . PHE B 2 434 ? 37.408 -32.014 24.478 1.00 26.96 ? 434 PHE A CG     1 
ATOM   6085 C CD1    . PHE B 2 434 ? 38.154 -31.614 25.572 1.00 25.10 ? 434 PHE A CD1    1 
ATOM   6086 C CD2    . PHE B 2 434 ? 38.068 -32.547 23.382 1.00 26.91 ? 434 PHE A CD2    1 
ATOM   6087 C CE1    . PHE B 2 434 ? 39.543 -31.738 25.580 1.00 24.88 ? 434 PHE A CE1    1 
ATOM   6088 C CE2    . PHE B 2 434 ? 39.456 -32.676 23.376 1.00 25.81 ? 434 PHE A CE2    1 
ATOM   6089 C CZ     . PHE B 2 434 ? 40.198 -32.270 24.479 1.00 24.55 ? 434 PHE A CZ     1 
ATOM   6090 H H      . PHE B 2 434 ? 35.944 -29.419 25.732 1.00 20.00 ? 434 PHE A H      1 
ATOM   6091 N N      . CYS B 2 435 ? 33.284 -30.249 23.041 1.00 46.48 ? 435 CYS A N      1 
ATOM   6092 C CA     . CYS B 2 435 ? 31.838 -30.052 23.041 1.00 47.72 ? 435 CYS A CA     1 
ATOM   6093 C C      . CYS B 2 435 ? 31.192 -30.803 21.880 1.00 47.12 ? 435 CYS A C      1 
ATOM   6094 O O      . CYS B 2 435 ? 31.847 -31.150 20.885 1.00 49.08 ? 435 CYS A O      1 
ATOM   6095 C CB     . CYS B 2 435 ? 31.544 -28.546 22.915 1.00 50.18 ? 435 CYS A CB     1 
ATOM   6096 S SG     . CYS B 2 435 ? 33.016 -27.455 23.118 1.00 52.64 ? 435 CYS A SG     1 
ATOM   6097 H H      . CYS B 2 435 ? 33.748 -30.335 22.164 1.00 20.00 ? 435 CYS A H      1 
ATOM   6098 N N      . THR B 2 436 ? 29.911 -31.102 22.030 1.00 47.19 ? 436 THR A N      1 
ATOM   6099 C CA     . THR B 2 436 ? 29.191 -31.811 20.982 1.00 47.49 ? 436 THR A CA     1 
ATOM   6100 C C      . THR B 2 436 ? 28.384 -30.825 20.171 1.00 46.31 ? 436 THR A C      1 
ATOM   6101 O O      . THR B 2 436 ? 27.937 -29.796 20.698 1.00 45.93 ? 436 THR A O      1 
ATOM   6102 C CB     . THR B 2 436 ? 28.229 -32.864 21.537 1.00 48.46 ? 436 THR A CB     1 
ATOM   6103 O OG1    . THR B 2 436 ? 27.266 -32.227 22.386 1.00 49.29 ? 436 THR A OG1    1 
ATOM   6104 C CG2    . THR B 2 436 ? 28.999 -33.935 22.320 1.00 46.19 ? 436 THR A CG2    1 
ATOM   6105 H H      . THR B 2 436 ? 29.432 -30.821 22.837 1.00 20.00 ? 436 THR A H      1 
ATOM   6106 H HG1    . THR B 2 436 ? 26.667 -32.892 22.739 1.00 20.00 ? 436 THR A HG1    1 
ATOM   6107 N N      . TYR B 2 437 ? 28.247 -31.117 18.882 1.00 46.94 ? 437 TYR A N      1 
ATOM   6108 C CA     . TYR B 2 437 ? 27.496 -30.259 17.984 1.00 47.34 ? 437 TYR A CA     1 
ATOM   6109 C C      . TYR B 2 437 ? 26.236 -30.989 17.532 1.00 46.41 ? 437 TYR A C      1 
ATOM   6110 O O      . TYR B 2 437 ? 26.188 -32.218 17.550 1.00 44.18 ? 437 TYR A O      1 
ATOM   6111 C CB     . TYR B 2 437 ? 28.386 -29.797 16.805 1.00 46.60 ? 437 TYR A CB     1 
ATOM   6112 C CG     . TYR B 2 437 ? 28.148 -30.470 15.470 1.00 47.05 ? 437 TYR A CG     1 
ATOM   6113 C CD1    . TYR B 2 437 ? 27.140 -30.018 14.625 1.00 48.14 ? 437 TYR A CD1    1 
ATOM   6114 C CD2    . TYR B 2 437 ? 28.949 -31.532 15.042 1.00 47.64 ? 437 TYR A CD2    1 
ATOM   6115 C CE1    . TYR B 2 437 ? 26.927 -30.594 13.394 1.00 47.97 ? 437 TYR A CE1    1 
ATOM   6116 C CE2    . TYR B 2 437 ? 28.743 -32.128 13.798 1.00 47.56 ? 437 TYR A CE2    1 
ATOM   6117 C CZ     . TYR B 2 437 ? 27.724 -31.651 12.976 1.00 47.40 ? 437 TYR A CZ     1 
ATOM   6118 O OH     . TYR B 2 437 ? 27.484 -32.221 11.736 1.00 49.50 ? 437 TYR A OH     1 
ATOM   6119 H H      . TYR B 2 437 ? 28.641 -31.922 18.520 1.00 20.00 ? 437 TYR A H      1 
ATOM   6120 H HH     . TYR B 2 437 ? 26.740 -31.760 11.314 1.00 20.00 ? 437 TYR A HH     1 
ATOM   6121 N N      . ASP B 2 438 ? 25.202 -30.222 17.208 1.00 47.66 ? 438 ASP A N      1 
ATOM   6122 C CA     . ASP B 2 438 ? 23.927 -30.765 16.761 1.00 49.06 ? 438 ASP A CA     1 
ATOM   6123 C C      . ASP B 2 438 ? 23.825 -30.427 15.273 1.00 45.71 ? 438 ASP A C      1 
ATOM   6124 O O      . ASP B 2 438 ? 23.557 -29.285 14.916 1.00 45.07 ? 438 ASP A O      1 
ATOM   6125 C CB     . ASP B 2 438 ? 22.813 -30.085 17.561 1.00 52.62 ? 438 ASP A CB     1 
ATOM   6126 C CG     . ASP B 2 438 ? 21.421 -30.564 17.182 1.00 53.91 ? 438 ASP A CG     1 
ATOM   6127 O OD1    . ASP B 2 438 ? 21.242 -31.236 16.131 1.00 56.58 ? 438 ASP A OD1    1 
ATOM   6128 O OD2    . ASP B 2 438 ? 20.492 -30.236 17.956 1.00 56.40 ? 438 ASP A OD2    1 
ATOM   6129 H H      . ASP B 2 438 ? 25.296 -29.236 17.267 1.00 20.00 ? 438 ASP A H      1 
ATOM   6130 N N      . ALA B 2 439 ? 23.991 -31.422 14.408 1.00 43.06 ? 439 ALA A N      1 
ATOM   6131 C CA     . ALA B 2 439 ? 23.958 -31.191 12.955 1.00 42.52 ? 439 ALA A CA     1 
ATOM   6132 C C      . ALA B 2 439 ? 22.721 -30.527 12.361 1.00 43.80 ? 439 ALA A C      1 
ATOM   6133 O O      . ALA B 2 439 ? 22.697 -30.175 11.177 1.00 40.54 ? 439 ALA A O      1 
ATOM   6134 C CB     . ALA B 2 439 ? 24.274 -32.465 12.197 1.00 41.00 ? 439 ALA A CB     1 
ATOM   6135 H H      . ALA B 2 439 ? 24.180 -32.315 14.744 1.00 20.00 ? 439 ALA A H      1 
ATOM   6136 N N      . ASP B 2 440 ? 21.672 -30.400 13.155 1.00 48.85 ? 440 ASP A N      1 
ATOM   6137 C CA     . ASP B 2 440 ? 20.477 -29.760 12.658 1.00 53.25 ? 440 ASP A CA     1 
ATOM   6138 C C      . ASP B 2 440 ? 20.295 -28.444 13.389 1.00 53.36 ? 440 ASP A C      1 
ATOM   6139 O O      . ASP B 2 440 ? 19.252 -28.207 14.011 1.00 54.78 ? 440 ASP A O      1 
ATOM   6140 C CB     . ASP B 2 440 ? 19.253 -30.661 12.838 1.00 57.41 ? 440 ASP A CB     1 
ATOM   6141 C CG     . ASP B 2 440 ? 18.031 -30.158 12.065 1.00 63.27 ? 440 ASP A CG     1 
ATOM   6142 O OD1    . ASP B 2 440 ? 18.101 -29.067 11.439 1.00 68.16 ? 440 ASP A OD1    1 
ATOM   6143 O OD2    . ASP B 2 440 ? 16.997 -30.871 12.085 1.00 60.93 ? 440 ASP A OD2    1 
ATOM   6144 H H      . ASP B 2 440 ? 21.702 -30.699 14.073 1.00 20.00 ? 440 ASP A H      1 
ATOM   6145 N N      . THR B 2 441 ? 21.324 -27.602 13.341 1.00 51.88 ? 441 THR A N      1 
ATOM   6146 C CA     . THR B 2 441 ? 21.265 -26.302 13.985 1.00 49.65 ? 441 THR A CA     1 
ATOM   6147 C C      . THR B 2 441 ? 21.841 -25.221 13.078 1.00 50.24 ? 441 THR A C      1 
ATOM   6148 O O      . THR B 2 441 ? 23.046 -24.965 13.079 1.00 50.70 ? 441 THR A O      1 
ATOM   6149 C CB     . THR B 2 441 ? 21.977 -26.305 15.361 1.00 48.70 ? 441 THR A CB     1 
ATOM   6150 O OG1    . THR B 2 441 ? 23.322 -26.777 15.218 1.00 46.54 ? 441 THR A OG1    1 
ATOM   6151 C CG2    . THR B 2 441 ? 21.236 -27.187 16.347 1.00 48.56 ? 441 THR A CG2    1 
ATOM   6152 H H      . THR B 2 441 ? 22.149 -27.843 12.868 1.00 20.00 ? 441 THR A H      1 
ATOM   6153 H HG1    . THR B 2 441 ? 23.746 -26.803 16.056 1.00 20.00 ? 441 THR A HG1    1 
ATOM   6154 N N      . LEU B 2 442 ? 20.973 -24.668 12.235 1.00 49.59 ? 442 LEU A N      1 
ATOM   6155 C CA     . LEU B 2 442 ? 21.311 -23.593 11.284 1.00 45.88 ? 442 LEU A CA     1 
ATOM   6156 C C      . LEU B 2 442 ? 20.194 -23.466 10.244 1.00 47.71 ? 442 LEU A C      1 
ATOM   6157 O O      . LEU B 2 442 ? 19.380 -24.381 10.069 1.00 49.41 ? 442 LEU A O      1 
ATOM   6158 C CB     . LEU B 2 442 ? 22.667 -23.826 10.582 1.00 38.84 ? 442 LEU A CB     1 
ATOM   6159 C CG     . LEU B 2 442 ? 22.815 -24.957 9.565  1.00 34.71 ? 442 LEU A CG     1 
ATOM   6160 C CD1    . LEU B 2 442 ? 24.172 -24.861 8.882  1.00 31.52 ? 442 LEU A CD1    1 
ATOM   6161 C CD2    . LEU B 2 442 ? 22.629 -26.301 10.233 1.00 33.19 ? 442 LEU A CD2    1 
ATOM   6162 H H      . LEU B 2 442 ? 20.056 -25.021 12.220 1.00 20.00 ? 442 LEU A H      1 
ATOM   6163 N N      . GLY B 2 454 ? 22.668 -17.832 24.005 1.00 50.30 ? 454 GLY A N      1 
ATOM   6164 C CA     . GLY B 2 454 ? 23.507 -16.763 23.488 1.00 46.40 ? 454 GLY A CA     1 
ATOM   6165 C C      . GLY B 2 454 ? 24.459 -17.206 22.388 1.00 42.65 ? 454 GLY A C      1 
ATOM   6166 O O      . GLY B 2 454 ? 24.747 -18.404 22.240 1.00 42.37 ? 454 GLY A O      1 
ATOM   6167 H H      . GLY B 2 454 ? 22.870 -18.227 24.874 1.00 20.00 ? 454 GLY A H      1 
ATOM   6168 N N      . VAL B 2 455 ? 24.924 -16.247 21.591 1.00 36.64 ? 455 VAL A N      1 
ATOM   6169 C CA     . VAL B 2 455 ? 25.841 -16.549 20.499 1.00 31.64 ? 455 VAL A CA     1 
ATOM   6170 C C      . VAL B 2 455 ? 27.257 -16.195 20.911 1.00 29.00 ? 455 VAL A C      1 
ATOM   6171 O O      . VAL B 2 455 ? 27.461 -15.458 21.869 1.00 29.24 ? 455 VAL A O      1 
ATOM   6172 C CB     . VAL B 2 455 ? 25.486 -15.711 19.246 1.00 30.60 ? 455 VAL A CB     1 
ATOM   6173 C CG1    . VAL B 2 455 ? 26.367 -16.098 18.065 1.00 30.89 ? 455 VAL A CG1    1 
ATOM   6174 C CG2    . VAL B 2 455 ? 24.012 -15.869 18.891 1.00 30.69 ? 455 VAL A CG2    1 
ATOM   6175 H H      . VAL B 2 455 ? 24.664 -15.311 21.755 1.00 20.00 ? 455 VAL A H      1 
ATOM   6176 N N      . ILE B 2 456 ? 28.232 -16.791 20.240 1.00 26.75 ? 456 ILE A N      1 
ATOM   6177 C CA     . ILE B 2 456 ? 29.643 -16.489 20.479 1.00 26.78 ? 456 ILE A CA     1 
ATOM   6178 C C      . ILE B 2 456 ? 30.300 -16.560 19.103 1.00 28.41 ? 456 ILE A C      1 
ATOM   6179 O O      . ILE B 2 456 ? 29.745 -17.169 18.184 1.00 28.83 ? 456 ILE A O      1 
ATOM   6180 C CB     . ILE B 2 456 ? 30.368 -17.448 21.516 1.00 24.00 ? 456 ILE A CB     1 
ATOM   6181 C CG1    . ILE B 2 456 ? 30.693 -18.808 20.906 1.00 21.72 ? 456 ILE A CG1    1 
ATOM   6182 C CG2    . ILE B 2 456 ? 29.497 -17.680 22.761 1.00 21.75 ? 456 ILE A CG2    1 
ATOM   6183 C CD1    . ILE B 2 456 ? 31.733 -19.593 21.691 1.00 22.75 ? 456 ILE A CD1    1 
ATOM   6184 H H      . ILE B 2 456 ? 27.995 -17.455 19.562 1.00 20.00 ? 456 ILE A H      1 
ATOM   6185 N N      . HIS B 2 457 ? 31.406 -15.842 18.919 1.00 31.92 ? 457 HIS A N      1 
ATOM   6186 C CA     . HIS B 2 457 ? 32.103 -15.854 17.637 1.00 33.32 ? 457 HIS A CA     1 
ATOM   6187 C C      . HIS B 2 457 ? 33.200 -16.931 17.614 1.00 31.82 ? 457 HIS A C      1 
ATOM   6188 O O      . HIS B 2 457 ? 33.665 -17.380 18.665 1.00 32.97 ? 457 HIS A O      1 
ATOM   6189 C CB     . HIS B 2 457 ? 32.622 -14.451 17.251 1.00 33.30 ? 457 HIS A CB     1 
ATOM   6190 C CG     . HIS B 2 457 ? 33.641 -13.878 18.189 1.00 35.41 ? 457 HIS A CG     1 
ATOM   6191 N ND1    . HIS B 2 457 ? 33.307 -13.352 19.427 1.00 35.75 ? 457 HIS A ND1    1 
ATOM   6192 C CD2    . HIS B 2 457 ? 34.979 -13.718 18.064 1.00 37.68 ? 457 HIS A CD2    1 
ATOM   6193 C CE1    . HIS B 2 457 ? 34.398 -12.905 20.014 1.00 37.08 ? 457 HIS A CE1    1 
ATOM   6194 N NE2    . HIS B 2 457 ? 35.430 -13.110 19.210 1.00 38.52 ? 457 HIS A NE2    1 
ATOM   6195 H H      . HIS B 2 457 ? 31.768 -15.331 19.657 1.00 20.00 ? 457 HIS A H      1 
ATOM   6196 H HD1    . HIS B 2 457 ? 32.411 -13.293 19.794 1.00 20.00 ? 457 HIS A HD1    1 
ATOM   6197 H HE2    . HIS B 2 457 ? 36.363 -12.848 19.368 1.00 20.00 ? 457 HIS A HE2    1 
ATOM   6198 N N      . TRP B 2 458 ? 33.648 -17.289 16.423 1.00 28.37 ? 458 TRP A N      1 
ATOM   6199 C CA     . TRP B 2 458 ? 34.632 -18.349 16.300 1.00 27.59 ? 458 TRP A CA     1 
ATOM   6200 C C      . TRP B 2 458 ? 35.449 -18.247 15.035 1.00 27.01 ? 458 TRP A C      1 
ATOM   6201 O O      . TRP B 2 458 ? 35.112 -17.483 14.133 1.00 28.20 ? 458 TRP A O      1 
ATOM   6202 C CB     . TRP B 2 458 ? 33.877 -19.664 16.266 1.00 26.82 ? 458 TRP A CB     1 
ATOM   6203 C CG     . TRP B 2 458 ? 32.708 -19.618 15.307 1.00 20.40 ? 458 TRP A CG     1 
ATOM   6204 C CD1    . TRP B 2 458 ? 31.441 -19.153 15.562 1.00 22.64 ? 458 TRP A CD1    1 
ATOM   6205 C CD2    . TRP B 2 458 ? 32.732 -20.004 13.937 1.00 17.79 ? 458 TRP A CD2    1 
ATOM   6206 N NE1    . TRP B 2 458 ? 30.678 -19.232 14.419 1.00 21.02 ? 458 TRP A NE1    1 
ATOM   6207 C CE2    . TRP B 2 458 ? 31.447 -19.745 13.407 1.00 17.57 ? 458 TRP A CE2    1 
ATOM   6208 C CE3    . TRP B 2 458 ? 33.718 -20.535 13.099 1.00 18.65 ? 458 TRP A CE3    1 
ATOM   6209 C CZ2    . TRP B 2 458 ? 31.130 -20.001 12.073 1.00 18.74 ? 458 TRP A CZ2    1 
ATOM   6210 C CZ3    . TRP B 2 458 ? 33.407 -20.791 11.765 1.00 17.69 ? 458 TRP A CZ3    1 
ATOM   6211 C CH2    . TRP B 2 458 ? 32.123 -20.524 11.268 1.00 18.06 ? 458 TRP A CH2    1 
ATOM   6212 H H      . TRP B 2 458 ? 33.337 -16.844 15.611 1.00 20.00 ? 458 TRP A H      1 
ATOM   6213 H HE1    . TRP B 2 458 ? 29.739 -18.962 14.312 1.00 20.00 ? 458 TRP A HE1    1 
ATOM   6214 N N      . VAL B 2 459 ? 36.475 -19.081 14.937 1.00 25.21 ? 459 VAL A N      1 
ATOM   6215 C CA     . VAL B 2 459 ? 37.346 -19.098 13.766 1.00 26.84 ? 459 VAL A CA     1 
ATOM   6216 C C      . VAL B 2 459 ? 37.968 -20.485 13.547 1.00 29.88 ? 459 VAL A C      1 
ATOM   6217 O O      . VAL B 2 459 ? 38.758 -20.952 14.380 1.00 28.11 ? 459 VAL A O      1 
ATOM   6218 C CB     . VAL B 2 459 ? 38.507 -18.042 13.885 1.00 23.89 ? 459 VAL A CB     1 
ATOM   6219 C CG1    . VAL B 2 459 ? 39.555 -18.293 12.832 1.00 24.49 ? 459 VAL A CG1    1 
ATOM   6220 C CG2    . VAL B 2 459 ? 37.972 -16.628 13.718 1.00 22.15 ? 459 VAL A CG2    1 
ATOM   6221 H H      . VAL B 2 459 ? 36.671 -19.681 15.675 1.00 20.00 ? 459 VAL A H      1 
ATOM   6222 N N      . SER B 2 460 ? 37.579 -21.146 12.453 1.00 32.02 ? 460 SER A N      1 
ATOM   6223 C CA     . SER B 2 460 ? 38.119 -22.460 12.095 1.00 34.18 ? 460 SER A CA     1 
ATOM   6224 C C      . SER B 2 460 ? 39.662 -22.434 12.155 1.00 35.07 ? 460 SER A C      1 
ATOM   6225 O O      . SER B 2 460 ? 40.326 -21.763 11.344 1.00 33.70 ? 460 SER A O      1 
ATOM   6226 C CB     . SER B 2 460 ? 37.663 -22.856 10.683 1.00 35.99 ? 460 SER A CB     1 
ATOM   6227 O OG     . SER B 2 460 ? 38.330 -24.024 10.214 1.00 38.98 ? 460 SER A OG     1 
ATOM   6228 H H      . SER B 2 460 ? 36.939 -20.717 11.839 1.00 20.00 ? 460 SER A H      1 
ATOM   6229 H HG     . SER B 2 460 ? 37.998 -24.243 9.347  1.00 20.00 ? 460 SER A HG     1 
ATOM   6230 N N      . ALA B 2 461 ? 40.207 -23.196 13.105 1.00 36.25 ? 461 ALA A N      1 
ATOM   6231 C CA     . ALA B 2 461 ? 41.649 -23.306 13.332 1.00 35.87 ? 461 ALA A CA     1 
ATOM   6232 C C      . ALA B 2 461 ? 42.425 -23.554 12.047 1.00 36.42 ? 461 ALA A C      1 
ATOM   6233 O O      . ALA B 2 461 ? 43.433 -22.902 11.778 1.00 36.94 ? 461 ALA A O      1 
ATOM   6234 C CB     . ALA B 2 461 ? 41.938 -24.431 14.330 1.00 36.40 ? 461 ALA A CB     1 
ATOM   6235 H H      . ALA B 2 461 ? 39.607 -23.739 13.659 1.00 20.00 ? 461 ALA A H      1 
ATOM   6236 N N      . ALA B 2 462 ? 41.935 -24.491 11.245 1.00 37.42 ? 462 ALA A N      1 
ATOM   6237 C CA     . ALA B 2 462 ? 42.578 -24.850 9.990  1.00 38.93 ? 462 ALA A CA     1 
ATOM   6238 C C      . ALA B 2 462 ? 42.633 -23.711 8.981  1.00 41.00 ? 462 ALA A C      1 
ATOM   6239 O O      . ALA B 2 462 ? 43.605 -23.576 8.248  1.00 41.03 ? 462 ALA A O      1 
ATOM   6240 C CB     . ALA B 2 462 ? 41.862 -26.045 9.377  1.00 38.71 ? 462 ALA A CB     1 
ATOM   6241 H H      . ALA B 2 462 ? 41.116 -24.937 11.507 1.00 20.00 ? 462 ALA A H      1 
ATOM   6242 N N      . HIS B 2 463 ? 41.561 -22.924 8.925  1.00 44.17 ? 463 HIS A N      1 
ATOM   6243 C CA     . HIS B 2 463 ? 41.451 -21.817 7.977  1.00 43.09 ? 463 HIS A CA     1 
ATOM   6244 C C      . HIS B 2 463 ? 41.707 -20.430 8.573  1.00 37.50 ? 463 HIS A C      1 
ATOM   6245 O O      . HIS B 2 463 ? 41.434 -19.425 7.917  1.00 40.29 ? 463 HIS A O      1 
ATOM   6246 C CB     . HIS B 2 463 ? 40.063 -21.839 7.341  1.00 49.64 ? 463 HIS A CB     1 
ATOM   6247 C CG     . HIS B 2 463 ? 39.634 -23.203 6.880  1.00 56.00 ? 463 HIS A CG     1 
ATOM   6248 N ND1    . HIS B 2 463 ? 38.472 -23.805 7.317  1.00 58.06 ? 463 HIS A ND1    1 
ATOM   6249 C CD2    . HIS B 2 463 ? 40.212 -24.077 6.022  1.00 58.40 ? 463 HIS A CD2    1 
ATOM   6250 C CE1    . HIS B 2 463 ? 38.353 -24.994 6.748  1.00 59.19 ? 463 HIS A CE1    1 
ATOM   6251 N NE2    . HIS B 2 463 ? 39.396 -25.182 5.958  1.00 58.61 ? 463 HIS A NE2    1 
ATOM   6252 H H      . HIS B 2 463 ? 40.843 -23.076 9.556  1.00 20.00 ? 463 HIS A H      1 
ATOM   6253 H HD1    . HIS B 2 463 ? 37.819 -23.399 7.937  1.00 20.00 ? 463 HIS A HD1    1 
ATOM   6254 H HE2    . HIS B 2 463 ? 39.553 -25.993 5.418  1.00 20.00 ? 463 HIS A HE2    1 
ATOM   6255 N N      . ALA B 2 464 ? 42.217 -20.375 9.801  1.00 33.07 ? 464 ALA A N      1 
ATOM   6256 C CA     . ALA B 2 464 ? 42.477 -19.107 10.477 1.00 26.15 ? 464 ALA A CA     1 
ATOM   6257 C C      . ALA B 2 464 ? 43.707 -18.308 10.003 1.00 23.05 ? 464 ALA A C      1 
ATOM   6258 O O      . ALA B 2 464 ? 44.806 -18.848 9.806  1.00 21.76 ? 464 ALA A O      1 
ATOM   6259 C CB     . ALA B 2 464 ? 42.549 -19.322 11.971 1.00 24.33 ? 464 ALA A CB     1 
ATOM   6260 H H      . ALA B 2 464 ? 42.479 -21.205 10.244 1.00 20.00 ? 464 ALA A H      1 
ATOM   6261 N N      . LEU B 2 465 ? 43.520 -16.996 9.903  1.00 21.29 ? 465 LEU A N      1 
ATOM   6262 C CA     . LEU B 2 465 ? 44.579 -16.094 9.474  1.00 22.98 ? 465 LEU A CA     1 
ATOM   6263 C C      . LEU B 2 465 ? 45.252 -15.432 10.675 1.00 24.11 ? 465 LEU A C      1 
ATOM   6264 O O      . LEU B 2 465 ? 44.585 -14.792 11.497 1.00 26.13 ? 465 LEU A O      1 
ATOM   6265 C CB     . LEU B 2 465 ? 43.997 -15.032 8.539  1.00 24.08 ? 465 LEU A CB     1 
ATOM   6266 C CG     . LEU B 2 465 ? 44.871 -13.885 8.012  1.00 25.32 ? 465 LEU A CG     1 
ATOM   6267 C CD1    . LEU B 2 465 ? 46.125 -14.353 7.224  1.00 23.70 ? 465 LEU A CD1    1 
ATOM   6268 C CD2    . LEU B 2 465 ? 43.948 -13.032 7.134  1.00 27.23 ? 465 LEU A CD2    1 
ATOM   6269 H H      . LEU B 2 465 ? 42.644 -16.622 10.111 1.00 20.00 ? 465 LEU A H      1 
ATOM   6270 N N      . PRO B 2 466 ? 46.581 -15.585 10.804 1.00 23.83 ? 466 PRO A N      1 
ATOM   6271 C CA     . PRO B 2 466 ? 47.331 -14.991 11.915 1.00 23.19 ? 466 PRO A CA     1 
ATOM   6272 C C      . PRO B 2 466 ? 47.197 -13.470 11.842 1.00 23.32 ? 466 PRO A C      1 
ATOM   6273 O O      . PRO B 2 466 ? 47.638 -12.869 10.862 1.00 23.22 ? 466 PRO A O      1 
ATOM   6274 C CB     . PRO B 2 466 ? 48.779 -15.399 11.615 1.00 22.26 ? 466 PRO A CB     1 
ATOM   6275 C CG     . PRO B 2 466 ? 48.640 -16.647 10.884 1.00 23.17 ? 466 PRO A CG     1 
ATOM   6276 C CD     . PRO B 2 466 ? 47.486 -16.364 9.945  1.00 24.21 ? 466 PRO A CD     1 
ATOM   6277 N N      . VAL B 2 467 ? 46.635 -12.851 12.876 1.00 21.36 ? 467 VAL A N      1 
ATOM   6278 C CA     . VAL B 2 467 ? 46.476 -11.407 12.851 1.00 20.28 ? 467 VAL A CA     1 
ATOM   6279 C C      . VAL B 2 467 ? 46.831 -10.714 14.150 1.00 17.92 ? 467 VAL A C      1 
ATOM   6280 O O      . VAL B 2 467 ? 46.487 -11.188 15.222 1.00 19.61 ? 467 VAL A O      1 
ATOM   6281 C CB     . VAL B 2 467 ? 45.051 -11.041 12.432 1.00 22.10 ? 467 VAL A CB     1 
ATOM   6282 C CG1    . VAL B 2 467 ? 44.185 -10.633 13.621 1.00 22.90 ? 467 VAL A CG1    1 
ATOM   6283 C CG2    . VAL B 2 467 ? 45.114 -9.985  11.377 1.00 22.16 ? 467 VAL A CG2    1 
ATOM   6284 H H      . VAL B 2 467 ? 46.290 -13.371 13.637 1.00 20.00 ? 467 VAL A H      1 
ATOM   6285 N N      . GLU B 2 468 ? 47.581 -9.624  14.057 1.00 18.12 ? 468 GLU A N      1 
ATOM   6286 C CA     . GLU B 2 468 ? 47.955 -8.881  15.254 1.00 16.27 ? 468 GLU A CA     1 
ATOM   6287 C C      . GLU B 2 468 ? 46.829 -7.915  15.555 1.00 15.59 ? 468 GLU A C      1 
ATOM   6288 O O      . GLU B 2 468 ? 46.113 -7.478  14.666 1.00 16.24 ? 468 GLU A O      1 
ATOM   6289 C CB     . GLU B 2 468 ? 49.262 -8.110  15.047 1.00 14.80 ? 468 GLU A CB     1 
ATOM   6290 C CG     . GLU B 2 468 ? 49.696 -7.322  16.281 1.00 16.61 ? 468 GLU A CG     1 
ATOM   6291 C CD     . GLU B 2 468 ? 51.131 -6.803  16.222 1.00 13.80 ? 468 GLU A CD     1 
ATOM   6292 O OE1    . GLU B 2 468 ? 52.072 -7.592  16.409 1.00 15.87 ? 468 GLU A OE1    1 
ATOM   6293 O OE2    . GLU B 2 468 ? 51.336 -5.591  16.039 1.00 12.72 ? 468 GLU A OE2    1 
ATOM   6294 H H      . GLU B 2 468 ? 47.856 -9.295  13.177 1.00 20.00 ? 468 GLU A H      1 
ATOM   6295 N N      . ILE B 2 469 ? 46.602 -7.629  16.815 1.00 15.04 ? 469 ILE A N      1 
ATOM   6296 C CA     . ILE B 2 469 ? 45.558 -6.687  17.141 1.00 16.86 ? 469 ILE A CA     1 
ATOM   6297 C C      . ILE B 2 469 ? 46.099 -5.641  18.098 1.00 17.46 ? 469 ILE A C      1 
ATOM   6298 O O      . ILE B 2 469 ? 46.907 -5.945  18.984 1.00 15.34 ? 469 ILE A O      1 
ATOM   6299 C CB     . ILE B 2 469 ? 44.319 -7.385  17.726 1.00 18.50 ? 469 ILE A CB     1 
ATOM   6300 C CG1    . ILE B 2 469 ? 43.777 -8.376  16.691 1.00 19.91 ? 469 ILE A CG1    1 
ATOM   6301 C CG2    . ILE B 2 469 ? 43.232 -6.348  18.060 1.00 18.63 ? 469 ILE A CG2    1 
ATOM   6302 C CD1    . ILE B 2 469 ? 42.435 -9.008  17.061 1.00 17.83 ? 469 ILE A CD1    1 
ATOM   6303 H H      . ILE B 2 469 ? 47.172 -8.010  17.508 1.00 20.00 ? 469 ILE A H      1 
ATOM   6304 N N      . ARG B 2 470 ? 45.756 -4.392  17.833 1.00 14.72 ? 470 ARG A N      1 
ATOM   6305 C CA     . ARG B 2 470 ? 46.211 -3.332  18.688 1.00 11.53 ? 470 ARG A CA     1 
ATOM   6306 C C      . ARG B 2 470 ? 45.003 -2.698  19.341 1.00 10.40 ? 470 ARG A C      1 
ATOM   6307 O O      . ARG B 2 470 ? 44.151 -2.112  18.673 1.00 12.24 ? 470 ARG A O      1 
ATOM   6308 C CB     . ARG B 2 470 ? 47.055 -2.361  17.892 1.00 12.84 ? 470 ARG A CB     1 
ATOM   6309 C CG     . ARG B 2 470 ? 48.312 -3.040  17.429 1.00 11.63 ? 470 ARG A CG     1 
ATOM   6310 C CD     . ARG B 2 470 ? 49.203 -2.106  16.706 1.00 13.62 ? 470 ARG A CD     1 
ATOM   6311 N NE     . ARG B 2 470 ? 50.473 -2.757  16.410 1.00 13.70 ? 470 ARG A NE     1 
ATOM   6312 C CZ     . ARG B 2 470 ? 51.661 -2.285  16.785 1.00 18.62 ? 470 ARG A CZ     1 
ATOM   6313 N NH1    . ARG B 2 470 ? 51.726 -1.149  17.469 1.00 16.72 ? 470 ARG A NH1    1 
ATOM   6314 N NH2    . ARG B 2 470 ? 52.780 -2.930  16.461 1.00 18.38 ? 470 ARG A NH2    1 
ATOM   6315 H H      . ARG B 2 470 ? 45.201 -4.194  17.050 1.00 20.00 ? 470 ARG A H      1 
ATOM   6316 H HE     . ARG B 2 470 ? 50.435 -3.546  15.840 1.00 20.00 ? 470 ARG A HE     1 
ATOM   6317 H HH11   . ARG B 2 470 ? 50.908 -0.627  17.687 1.00 20.00 ? 470 ARG A HH11   1 
ATOM   6318 H HH12   . ARG B 2 470 ? 52.627 -0.807  17.751 1.00 20.00 ? 470 ARG A HH12   1 
ATOM   6319 H HH21   . ARG B 2 470 ? 52.690 -3.759  15.885 1.00 20.00 ? 470 ARG A HH21   1 
ATOM   6320 H HH22   . ARG B 2 470 ? 53.653 -2.586  16.728 1.00 20.00 ? 470 ARG A HH22   1 
ATOM   6321 N N      . LEU B 2 471 ? 44.863 -2.988  20.632 1.00 9.60  ? 471 LEU A N      1 
ATOM   6322 C CA     . LEU B 2 471 ? 43.757 -2.494  21.446 1.00 7.50  ? 471 LEU A CA     1 
ATOM   6323 C C      . LEU B 2 471 ? 44.196 -1.173  22.053 1.00 5.76  ? 471 LEU A C      1 
ATOM   6324 O O      . LEU B 2 471 ? 45.090 -1.130  22.894 1.00 6.50  ? 471 LEU A O      1 
ATOM   6325 C CB     . LEU B 2 471 ? 43.442 -3.525  22.532 1.00 8.97  ? 471 LEU A CB     1 
ATOM   6326 C CG     . LEU B 2 471 ? 42.890 -4.841  21.986 1.00 11.79 ? 471 LEU A CG     1 
ATOM   6327 C CD1    . LEU B 2 471 ? 43.061 -5.992  22.955 1.00 13.23 ? 471 LEU A CD1    1 
ATOM   6328 C CD2    . LEU B 2 471 ? 41.439 -4.626  21.662 1.00 10.19 ? 471 LEU A CD2    1 
ATOM   6329 H H      . LEU B 2 471 ? 45.558 -3.539  21.057 1.00 20.00 ? 471 LEU A H      1 
ATOM   6330 N N      . TYR B 2 472 ? 43.585 -0.092  21.589 1.00 3.56  ? 472 TYR A N      1 
ATOM   6331 C CA     . TYR B 2 472 ? 43.915 1.262   22.023 1.00 2.11  ? 472 TYR A CA     1 
ATOM   6332 C C      . TYR B 2 472 ? 42.926 1.737   23.055 1.00 3.07  ? 472 TYR A C      1 
ATOM   6333 O O      . TYR B 2 472 ? 41.742 1.418   22.968 1.00 2.41  ? 472 TYR A O      1 
ATOM   6334 C CB     . TYR B 2 472 ? 43.875 2.204   20.806 1.00 2.92  ? 472 TYR A CB     1 
ATOM   6335 C CG     . TYR B 2 472 ? 44.992 1.969   19.811 1.00 2.00  ? 472 TYR A CG     1 
ATOM   6336 C CD1    . TYR B 2 472 ? 46.309 2.232   20.170 1.00 2.69  ? 472 TYR A CD1    1 
ATOM   6337 C CD2    . TYR B 2 472 ? 44.747 1.439   18.542 1.00 2.00  ? 472 TYR A CD2    1 
ATOM   6338 C CE1    . TYR B 2 472 ? 47.377 1.965   19.300 1.00 3.41  ? 472 TYR A CE1    1 
ATOM   6339 C CE2    . TYR B 2 472 ? 45.811 1.168   17.659 1.00 2.08  ? 472 TYR A CE2    1 
ATOM   6340 C CZ     . TYR B 2 472 ? 47.121 1.435   18.057 1.00 3.81  ? 472 TYR A CZ     1 
ATOM   6341 O OH     . TYR B 2 472 ? 48.210 1.154   17.259 1.00 7.60  ? 472 TYR A OH     1 
ATOM   6342 H H      . TYR B 2 472 ? 42.868 -0.219  20.926 1.00 20.00 ? 472 TYR A H      1 
ATOM   6343 H HH     . TYR B 2 472 ? 47.910 0.780   16.418 1.00 20.00 ? 472 TYR A HH     1 
ATOM   6344 N N      . ASP B 2 473 ? 43.421 2.469   24.048 1.00 4.92  ? 473 ASP A N      1 
ATOM   6345 C CA     . ASP B 2 473 ? 42.596 3.045   25.110 1.00 6.96  ? 473 ASP A CA     1 
ATOM   6346 C C      . ASP B 2 473 ? 43.000 4.519   25.214 1.00 8.71  ? 473 ASP A C      1 
ATOM   6347 O O      . ASP B 2 473 ? 43.869 4.981   24.459 1.00 6.61  ? 473 ASP A O      1 
ATOM   6348 C CB     . ASP B 2 473 ? 42.843 2.342   26.435 1.00 9.66  ? 473 ASP A CB     1 
ATOM   6349 C CG     . ASP B 2 473 ? 41.723 2.577   27.447 1.00 15.18 ? 473 ASP A CG     1 
ATOM   6350 O OD1    . ASP B 2 473 ? 40.650 3.093   27.052 1.00 16.79 ? 473 ASP A OD1    1 
ATOM   6351 O OD2    . ASP B 2 473 ? 41.918 2.220   28.641 1.00 14.02 ? 473 ASP A OD2    1 
ATOM   6352 H H      . ASP B 2 473 ? 44.375 2.625   24.068 1.00 20.00 ? 473 ASP A H      1 
ATOM   6353 N N      . ARG B 2 474 ? 42.389 5.276   26.125 1.00 7.59  ? 474 ARG A N      1 
ATOM   6354 C CA     . ARG B 2 474 ? 42.756 6.675   26.193 1.00 9.91  ? 474 ARG A CA     1 
ATOM   6355 C C      . ARG B 2 474 ? 44.219 6.856   26.595 1.00 7.82  ? 474 ARG A C      1 
ATOM   6356 O O      . ARG B 2 474 ? 44.768 6.061   27.341 1.00 7.94  ? 474 ARG A O      1 
ATOM   6357 C CB     . ARG B 2 474 ? 41.792 7.482   27.047 1.00 16.43 ? 474 ARG A CB     1 
ATOM   6358 C CG     . ARG B 2 474 ? 41.679 7.066   28.482 1.00 25.39 ? 474 ARG A CG     1 
ATOM   6359 C CD     . ARG B 2 474 ? 40.272 6.638   28.824 1.00 32.40 ? 474 ARG A CD     1 
ATOM   6360 N NE     . ARG B 2 474 ? 39.275 7.200   27.902 1.00 38.60 ? 474 ARG A NE     1 
ATOM   6361 C CZ     . ARG B 2 474 ? 37.994 7.403   28.219 1.00 44.23 ? 474 ARG A CZ     1 
ATOM   6362 N NH1    . ARG B 2 474 ? 37.560 7.147   29.457 1.00 46.18 ? 474 ARG A NH1    1 
ATOM   6363 N NH2    . ARG B 2 474 ? 37.160 7.897   27.312 1.00 47.54 ? 474 ARG A NH2    1 
ATOM   6364 H H      . ARG B 2 474 ? 41.721 4.898   26.733 1.00 20.00 ? 474 ARG A H      1 
ATOM   6365 H HE     . ARG B 2 474 ? 39.546 7.468   27.006 1.00 20.00 ? 474 ARG A HE     1 
ATOM   6366 H HH11   . ARG B 2 474 ? 38.196 6.778   30.144 1.00 20.00 ? 474 ARG A HH11   1 
ATOM   6367 H HH12   . ARG B 2 474 ? 36.604 7.292   29.700 1.00 20.00 ? 474 ARG A HH12   1 
ATOM   6368 H HH21   . ARG B 2 474 ? 37.495 8.166   26.416 1.00 20.00 ? 474 ARG A HH21   1 
ATOM   6369 H HH22   . ARG B 2 474 ? 36.206 8.085   27.572 1.00 20.00 ? 474 ARG A HH22   1 
ATOM   6370 N N      . LEU B 2 475 ? 44.857 7.898   26.082 1.00 5.36  ? 475 LEU A N      1 
ATOM   6371 C CA     . LEU B 2 475 ? 46.269 8.141   26.355 1.00 3.67  ? 475 LEU A CA     1 
ATOM   6372 C C      . LEU B 2 475 ? 46.549 8.547   27.786 1.00 2.57  ? 475 LEU A C      1 
ATOM   6373 O O      . LEU B 2 475 ? 47.605 8.227   28.312 1.00 4.76  ? 475 LEU A O      1 
ATOM   6374 C CB     . LEU B 2 475 ? 46.828 9.212   25.424 1.00 2.01  ? 475 LEU A CB     1 
ATOM   6375 C CG     . LEU B 2 475 ? 48.074 8.920   24.596 1.00 2.01  ? 475 LEU A CG     1 
ATOM   6376 C CD1    . LEU B 2 475 ? 48.652 10.244  24.158 1.00 2.01  ? 475 LEU A CD1    1 
ATOM   6377 C CD2    . LEU B 2 475 ? 49.091 8.183   25.403 1.00 2.00  ? 475 LEU A CD2    1 
ATOM   6378 H H      . LEU B 2 475 ? 44.375 8.497   25.493 1.00 20.00 ? 475 LEU A H      1 
ATOM   6379 N N      . PHE B 2 476 ? 45.635 9.277   28.410 1.00 2.00  ? 476 PHE A N      1 
ATOM   6380 C CA     . PHE B 2 476 ? 45.841 9.747   29.773 1.00 3.11  ? 476 PHE A CA     1 
ATOM   6381 C C      . PHE B 2 476 ? 44.906 9.122   30.779 1.00 2.00  ? 476 PHE A C      1 
ATOM   6382 O O      . PHE B 2 476 ? 43.787 8.739   30.440 1.00 2.67  ? 476 PHE A O      1 
ATOM   6383 C CB     . PHE B 2 476 ? 45.738 11.264  29.814 1.00 2.01  ? 476 PHE A CB     1 
ATOM   6384 C CG     . PHE B 2 476 ? 46.814 11.926  29.050 1.00 2.01  ? 476 PHE A CG     1 
ATOM   6385 C CD1    . PHE B 2 476 ? 48.065 12.079  29.599 1.00 2.01  ? 476 PHE A CD1    1 
ATOM   6386 C CD2    . PHE B 2 476 ? 46.606 12.312  27.752 1.00 2.01  ? 476 PHE A CD2    1 
ATOM   6387 C CE1    . PHE B 2 476 ? 49.111 12.608  28.856 1.00 2.01  ? 476 PHE A CE1    1 
ATOM   6388 C CE2    . PHE B 2 476 ? 47.644 12.845  26.993 1.00 2.01  ? 476 PHE A CE2    1 
ATOM   6389 C CZ     . PHE B 2 476 ? 48.901 12.992  27.551 1.00 2.01  ? 476 PHE A CZ     1 
ATOM   6390 H H      . PHE B 2 476 ? 44.787 9.462   27.983 1.00 20.00 ? 476 PHE A H      1 
ATOM   6391 N N      . SER B 2 477 ? 45.349 9.019   32.024 1.00 2.00  ? 477 SER A N      1 
ATOM   6392 C CA     . SER B 2 477 ? 44.517 8.390   33.027 1.00 2.00  ? 477 SER A CA     1 
ATOM   6393 C C      . SER B 2 477 ? 43.717 9.378   33.840 1.00 2.44  ? 477 SER A C      1 
ATOM   6394 O O      . SER B 2 477 ? 43.058 9.005   34.799 1.00 4.96  ? 477 SER A O      1 
ATOM   6395 C CB     . SER B 2 477 ? 45.353 7.482   33.920 1.00 2.35  ? 477 SER A CB     1 
ATOM   6396 O OG     . SER B 2 477 ? 46.465 8.201   34.414 1.00 2.82  ? 477 SER A OG     1 
ATOM   6397 H H      . SER B 2 477 ? 46.241 9.359   32.280 1.00 20.00 ? 477 SER A H      1 
ATOM   6398 H HG     . SER B 2 477 ? 46.987 7.590   34.992 1.00 20.00 ? 477 SER A HG     1 
ATOM   6399 N N      . VAL B 2 478 ? 43.756 10.645  33.469 1.00 2.74  ? 478 VAL A N      1 
ATOM   6400 C CA     . VAL B 2 478 ? 42.970 11.653  34.178 1.00 2.01  ? 478 VAL A CA     1 
ATOM   6401 C C      . VAL B 2 478 ? 42.231 12.376  33.074 1.00 2.57  ? 478 VAL A C      1 
ATOM   6402 O O      . VAL B 2 478 ? 42.684 12.392  31.930 1.00 3.43  ? 478 VAL A O      1 
ATOM   6403 C CB     . VAL B 2 478 ? 43.854 12.623  34.946 1.00 2.00  ? 478 VAL A CB     1 
ATOM   6404 C CG1    . VAL B 2 478 ? 44.447 11.933  36.135 1.00 2.00  ? 478 VAL A CG1    1 
ATOM   6405 C CG2    . VAL B 2 478 ? 44.990 13.106  34.050 1.00 2.00  ? 478 VAL A CG2    1 
ATOM   6406 H H      . VAL B 2 478 ? 44.335 10.904  32.721 1.00 20.00 ? 478 VAL A H      1 
ATOM   6407 N N      . PRO B 2 479 ? 41.100 13.004  33.394 1.00 2.66  ? 479 PRO A N      1 
ATOM   6408 C CA     . PRO B 2 479 ? 40.357 13.705  32.346 1.00 4.12  ? 479 PRO A CA     1 
ATOM   6409 C C      . PRO B 2 479 ? 40.994 14.995  31.828 1.00 7.16  ? 479 PRO A C      1 
ATOM   6410 O O      . PRO B 2 479 ? 40.749 15.376  30.708 1.00 8.60  ? 479 PRO A O      1 
ATOM   6411 C CB     . PRO B 2 479 ? 39.021 13.988  33.014 1.00 3.37  ? 479 PRO A CB     1 
ATOM   6412 C CG     . PRO B 2 479 ? 38.915 12.945  34.056 1.00 3.49  ? 479 PRO A CG     1 
ATOM   6413 C CD     . PRO B 2 479 ? 40.300 12.929  34.619 1.00 2.01  ? 479 PRO A CD     1 
ATOM   6414 N N      . ASN B 2 480 ? 41.738 15.710  32.652 1.00 11.15 ? 480 ASN A N      1 
ATOM   6415 C CA     . ASN B 2 480 ? 42.373 16.945  32.191 1.00 15.67 ? 480 ASN A CA     1 
ATOM   6416 C C      . ASN B 2 480 ? 43.899 16.901  32.388 1.00 11.41 ? 480 ASN A C      1 
ATOM   6417 O O      . ASN B 2 480 ? 44.482 17.721  33.110 1.00 11.87 ? 480 ASN A O      1 
ATOM   6418 C CB     . ASN B 2 480 ? 41.751 18.151  32.898 1.00 25.87 ? 480 ASN A CB     1 
ATOM   6419 C CG     . ASN B 2 480 ? 42.386 19.472  32.479 1.00 33.12 ? 480 ASN A CG     1 
ATOM   6420 O OD1    . ASN B 2 480 ? 43.361 19.501  31.719 1.00 39.40 ? 480 ASN A OD1    1 
ATOM   6421 N ND2    . ASN B 2 480 ? 41.837 20.578  32.979 1.00 39.64 ? 480 ASN A ND2    1 
ATOM   6422 H H      . ASN B 2 480 ? 41.883 15.406  33.574 1.00 20.00 ? 480 ASN A H      1 
ATOM   6423 H HD21   . ASN B 2 480 ? 42.212 21.442  32.727 1.00 20.00 ? 480 ASN A HD21   1 
ATOM   6424 H HD22   . ASN B 2 480 ? 41.062 20.505  33.593 1.00 20.00 ? 480 ASN A HD22   1 
ATOM   6425 N N      . PRO B 2 481 ? 44.573 15.951  31.728 1.00 6.04  ? 481 PRO A N      1 
ATOM   6426 C CA     . PRO B 2 481 ? 46.025 15.860  31.867 1.00 2.81  ? 481 PRO A CA     1 
ATOM   6427 C C      . PRO B 2 481 ? 46.691 17.207  31.628 1.00 4.51  ? 481 PRO A C      1 
ATOM   6428 O O      . PRO B 2 481 ? 47.845 17.412  31.991 1.00 4.54  ? 481 PRO A O      1 
ATOM   6429 C CB     . PRO B 2 481 ? 46.417 14.880  30.766 1.00 2.00  ? 481 PRO A CB     1 
ATOM   6430 C CG     . PRO B 2 481 ? 45.390 15.122  29.727 1.00 2.91  ? 481 PRO A CG     1 
ATOM   6431 C CD     . PRO B 2 481 ? 44.117 15.214  30.541 1.00 4.47  ? 481 PRO A CD     1 
ATOM   6432 N N      . GLY B 2 482 ? 45.976 18.114  30.980 1.00 6.55  ? 482 GLY A N      1 
ATOM   6433 C CA     . GLY B 2 482 ? 46.538 19.421  30.723 1.00 12.40 ? 482 GLY A CA     1 
ATOM   6434 C C      . GLY B 2 482 ? 46.845 20.132  32.018 1.00 16.28 ? 482 GLY A C      1 
ATOM   6435 O O      . GLY B 2 482 ? 47.966 20.592  32.256 1.00 18.67 ? 482 GLY A O      1 
ATOM   6436 H H      . GLY B 2 482 ? 45.078 17.918  30.674 1.00 20.00 ? 482 GLY A H      1 
ATOM   6437 N N      . ALA B 2 483 ? 45.852 20.159  32.892 1.00 20.50 ? 483 ALA A N      1 
ATOM   6438 C CA     . ALA B 2 483 ? 45.971 20.801  34.186 1.00 21.74 ? 483 ALA A CA     1 
ATOM   6439 C C      . ALA B 2 483 ? 46.839 20.051  35.183 1.00 22.43 ? 483 ALA A C      1 
ATOM   6440 O O      . ALA B 2 483 ? 46.672 20.226  36.393 1.00 22.54 ? 483 ALA A O      1 
ATOM   6441 C CB     . ALA B 2 483 ? 44.602 21.002  34.774 1.00 24.34 ? 483 ALA A CB     1 
ATOM   6442 H H      . ALA B 2 483 ? 45.020 19.718  32.669 1.00 20.00 ? 483 ALA A H      1 
ATOM   6443 N N      . ALA B 2 484 ? 47.724 19.186  34.705 1.00 24.91 ? 484 ALA A N      1 
ATOM   6444 C CA     . ALA B 2 484 ? 48.580 18.439  35.610 1.00 27.97 ? 484 ALA A CA     1 
ATOM   6445 C C      . ALA B 2 484 ? 49.962 19.070  35.665 1.00 30.33 ? 484 ALA A C      1 
ATOM   6446 O O      . ALA B 2 484 ? 50.425 19.660  34.686 1.00 30.77 ? 484 ALA A O      1 
ATOM   6447 C CB     . ALA B 2 484 ? 48.659 16.986  35.182 1.00 29.99 ? 484 ALA A CB     1 
ATOM   6448 H H      . ALA B 2 484 ? 47.821 19.043  33.742 1.00 20.00 ? 484 ALA A H      1 
ATOM   6449 N N      . ASP B 2 485 ? 50.625 18.922  36.812 1.00 32.20 ? 485 ASP A N      1 
ATOM   6450 C CA     . ASP B 2 485 ? 51.961 19.477  37.041 1.00 35.93 ? 485 ASP A CA     1 
ATOM   6451 C C      . ASP B 2 485 ? 52.938 18.905  36.037 1.00 32.88 ? 485 ASP A C      1 
ATOM   6452 O O      . ASP B 2 485 ? 53.933 19.535  35.674 1.00 29.29 ? 485 ASP A O      1 
ATOM   6453 C CB     . ASP B 2 485 ? 52.423 19.124  38.450 1.00 41.61 ? 485 ASP A CB     1 
ATOM   6454 C CG     . ASP B 2 485 ? 51.323 19.304  39.472 1.00 49.14 ? 485 ASP A CG     1 
ATOM   6455 O OD1    . ASP B 2 485 ? 51.009 20.467  39.807 1.00 51.35 ? 485 ASP A OD1    1 
ATOM   6456 O OD2    . ASP B 2 485 ? 50.743 18.287  39.913 1.00 52.14 ? 485 ASP A OD2    1 
ATOM   6457 H H      . ASP B 2 485 ? 50.184 18.443  37.530 1.00 20.00 ? 485 ASP A H      1 
ATOM   6458 N N      . ASP B 2 486 ? 52.654 17.685  35.609 1.00 27.28 ? 486 ASP A N      1 
ATOM   6459 C CA     . ASP B 2 486 ? 53.480 16.982  34.638 1.00 20.76 ? 486 ASP A CA     1 
ATOM   6460 C C      . ASP B 2 486 ? 52.555 15.998  33.959 1.00 13.35 ? 486 ASP A C      1 
ATOM   6461 O O      . ASP B 2 486 ? 52.337 14.905  34.463 1.00 12.70 ? 486 ASP A O      1 
ATOM   6462 C CB     . ASP B 2 486 ? 54.603 16.221  35.346 1.00 23.35 ? 486 ASP A CB     1 
ATOM   6463 C CG     . ASP B 2 486 ? 55.642 15.682  34.385 1.00 25.33 ? 486 ASP A CG     1 
ATOM   6464 O OD1    . ASP B 2 486 ? 55.370 15.631  33.162 1.00 28.00 ? 486 ASP A OD1    1 
ATOM   6465 O OD2    . ASP B 2 486 ? 56.745 15.312  34.853 1.00 29.02 ? 486 ASP A OD2    1 
ATOM   6466 H H      . ASP B 2 486 ? 51.882 17.216  35.970 1.00 20.00 ? 486 ASP A H      1 
ATOM   6467 N N      . PHE B 2 487 ? 52.014 16.384  32.810 1.00 8.07  ? 487 PHE A N      1 
ATOM   6468 C CA     . PHE B 2 487 ? 51.087 15.511  32.095 1.00 2.00  ? 487 PHE A CA     1 
ATOM   6469 C C      . PHE B 2 487 ? 51.748 14.190  31.739 1.00 2.00  ? 487 PHE A C      1 
ATOM   6470 O O      . PHE B 2 487 ? 51.076 13.173  31.720 1.00 2.00  ? 487 PHE A O      1 
ATOM   6471 C CB     . PHE B 2 487 ? 50.512 16.200  30.844 1.00 2.00  ? 487 PHE A CB     1 
ATOM   6472 C CG     . PHE B 2 487 ? 51.501 16.385  29.715 1.00 2.01  ? 487 PHE A CG     1 
ATOM   6473 C CD1    . PHE B 2 487 ? 52.638 17.147  29.861 1.00 2.01  ? 487 PHE A CD1    1 
ATOM   6474 C CD2    . PHE B 2 487 ? 51.259 15.828  28.485 1.00 2.00  ? 487 PHE A CD2    1 
ATOM   6475 C CE1    . PHE B 2 487 ? 53.503 17.344  28.794 1.00 2.00  ? 487 PHE A CE1    1 
ATOM   6476 C CE2    . PHE B 2 487 ? 52.124 16.027  27.419 1.00 2.00  ? 487 PHE A CE2    1 
ATOM   6477 C CZ     . PHE B 2 487 ? 53.240 16.782  27.576 1.00 2.00  ? 487 PHE A CZ     1 
ATOM   6478 H H      . PHE B 2 487 ? 52.245 17.275  32.454 1.00 20.00 ? 487 PHE A H      1 
ATOM   6479 N N      . LEU B 2 488 ? 53.063 14.179  31.508 1.00 2.00  ? 488 LEU A N      1 
ATOM   6480 C CA     . LEU B 2 488 ? 53.706 12.917  31.148 1.00 2.00  ? 488 LEU A CA     1 
ATOM   6481 C C      . LEU B 2 488 ? 53.538 11.857  32.223 1.00 2.28  ? 488 LEU A C      1 
ATOM   6482 O O      . LEU B 2 488 ? 53.162 10.713  31.938 1.00 4.02  ? 488 LEU A O      1 
ATOM   6483 C CB     . LEU B 2 488 ? 55.183 13.103  30.817 1.00 2.01  ? 488 LEU A CB     1 
ATOM   6484 C CG     . LEU B 2 488 ? 55.505 13.732  29.455 1.00 2.01  ? 488 LEU A CG     1 
ATOM   6485 C CD1    . LEU B 2 488 ? 56.946 13.445  29.086 1.00 2.00  ? 488 LEU A CD1    1 
ATOM   6486 C CD2    . LEU B 2 488 ? 54.608 13.197  28.380 1.00 2.01  ? 488 LEU A CD2    1 
ATOM   6487 H H      . LEU B 2 488 ? 53.587 14.996  31.590 1.00 20.00 ? 488 LEU A H      1 
ATOM   6488 N N      . SER B 2 489 ? 53.720 12.245  33.473 1.00 2.00  ? 489 SER A N      1 
ATOM   6489 C CA     . SER B 2 489 ? 53.606 11.268  34.531 1.00 2.00  ? 489 SER A CA     1 
ATOM   6490 C C      . SER B 2 489 ? 52.189 10.751  34.686 1.00 2.01  ? 489 SER A C      1 
ATOM   6491 O O      . SER B 2 489 ? 51.944 9.802   35.438 1.00 2.92  ? 489 SER A O      1 
ATOM   6492 C CB     . SER B 2 489 ? 54.144 11.806  35.855 1.00 2.01  ? 489 SER A CB     1 
ATOM   6493 O OG     . SER B 2 489 ? 53.396 12.908  36.321 1.00 4.26  ? 489 SER A OG     1 
ATOM   6494 H H      . SER B 2 489 ? 53.903 13.163  33.709 1.00 20.00 ? 489 SER A H      1 
ATOM   6495 H HG     . SER B 2 489 ? 53.786 13.189  37.160 1.00 20.00 ? 489 SER A HG     1 
ATOM   6496 N N      . VAL B 2 490 ? 51.258 11.335  33.950 1.00 2.00  ? 490 VAL A N      1 
ATOM   6497 C CA     . VAL B 2 490 ? 49.875 10.897  34.033 1.00 2.81  ? 490 VAL A CA     1 
ATOM   6498 C C      . VAL B 2 490 ? 49.399 10.105  32.755 1.00 2.87  ? 490 VAL A C      1 
ATOM   6499 O O      . VAL B 2 490 ? 48.205 9.931   32.482 1.00 3.12  ? 490 VAL A O      1 
ATOM   6500 C CB     . VAL B 2 490 ? 48.980 12.088  34.412 1.00 2.01  ? 490 VAL A CB     1 
ATOM   6501 C CG1    . VAL B 2 490 ? 48.636 12.883  33.223 1.00 2.01  ? 490 VAL A CG1    1 
ATOM   6502 C CG2    . VAL B 2 490 ? 47.762 11.622  35.078 1.00 2.00  ? 490 VAL A CG2    1 
ATOM   6503 H H      . VAL B 2 490 ? 51.509 12.066  33.359 1.00 20.00 ? 490 VAL A H      1 
ATOM   6504 N N      . ILE B 2 491 ? 50.357 9.609   31.979 1.00 2.00  ? 491 ILE A N      1 
ATOM   6505 C CA     . ILE B 2 491 ? 50.033 8.816   30.801 1.00 2.01  ? 491 ILE A CA     1 
ATOM   6506 C C      . ILE B 2 491 ? 49.456 7.455   31.245 1.00 2.01  ? 491 ILE A C      1 
ATOM   6507 O O      . ILE B 2 491 ? 49.829 6.922   32.305 1.00 3.39  ? 491 ILE A O      1 
ATOM   6508 C CB     . ILE B 2 491 ? 51.293 8.546   29.971 1.00 2.01  ? 491 ILE A CB     1 
ATOM   6509 C CG1    . ILE B 2 491 ? 51.759 9.831   29.289 1.00 2.00  ? 491 ILE A CG1    1 
ATOM   6510 C CG2    . ILE B 2 491 ? 51.019 7.500   28.944 1.00 2.00  ? 491 ILE A CG2    1 
ATOM   6511 C CD1    . ILE B 2 491 ? 52.858 9.664   28.304 1.00 2.00  ? 491 ILE A CD1    1 
ATOM   6512 H H      . ILE B 2 491 ? 51.305 9.757   32.223 1.00 20.00 ? 491 ILE A H      1 
ATOM   6513 N N      . ASN B 2 492 ? 48.550 6.893   30.449 1.00 2.01  ? 492 ASN A N      1 
ATOM   6514 C CA     . ASN B 2 492 ? 47.961 5.585   30.746 1.00 2.00  ? 492 ASN A CA     1 
ATOM   6515 C C      . ASN B 2 492 ? 48.917 4.484   30.275 1.00 2.00  ? 492 ASN A C      1 
ATOM   6516 O O      . ASN B 2 492 ? 49.247 4.422   29.086 1.00 2.00  ? 492 ASN A O      1 
ATOM   6517 C CB     . ASN B 2 492 ? 46.624 5.419   30.031 1.00 2.00  ? 492 ASN A CB     1 
ATOM   6518 C CG     . ASN B 2 492 ? 46.012 4.061   30.284 1.00 2.00  ? 492 ASN A CG     1 
ATOM   6519 O OD1    . ASN B 2 492 ? 46.468 3.338   31.166 1.00 2.00  ? 492 ASN A OD1    1 
ATOM   6520 N ND2    . ASN B 2 492 ? 44.970 3.703   29.526 1.00 2.00  ? 492 ASN A ND2    1 
ATOM   6521 H H      . ASN B 2 492 ? 48.292 7.349   29.678 1.00 20.00 ? 492 ASN A H      1 
ATOM   6522 H HD21   . ASN B 2 492 ? 44.534 2.851   29.704 1.00 20.00 ? 492 ASN A HD21   1 
ATOM   6523 H HD22   . ASN B 2 492 ? 44.651 4.330   28.819 1.00 20.00 ? 492 ASN A HD22   1 
ATOM   6524 N N      . PRO B 2 493 ? 49.307 3.551   31.170 1.00 2.00  ? 493 PRO A N      1 
ATOM   6525 C CA     . PRO B 2 493 ? 50.223 2.578   30.565 1.00 2.00  ? 493 PRO A CA     1 
ATOM   6526 C C      . PRO B 2 493 ? 49.517 1.555   29.713 1.00 2.75  ? 493 PRO A C      1 
ATOM   6527 O O      . PRO B 2 493 ? 50.166 0.822   28.960 1.00 2.52  ? 493 PRO A O      1 
ATOM   6528 C CB     . PRO B 2 493 ? 50.958 1.975   31.749 1.00 2.01  ? 493 PRO A CB     1 
ATOM   6529 C CG     . PRO B 2 493 ? 50.092 2.262   32.900 1.00 2.00  ? 493 PRO A CG     1 
ATOM   6530 C CD     . PRO B 2 493 ? 49.553 3.636   32.610 1.00 2.00  ? 493 PRO A CD     1 
ATOM   6531 N N      . GLU B 2 494 ? 48.195 1.545   29.771 1.00 3.87  ? 494 GLU A N      1 
ATOM   6532 C CA     . GLU B 2 494 ? 47.447 0.648   28.930 1.00 10.10 ? 494 GLU A CA     1 
ATOM   6533 C C      . GLU B 2 494 ? 46.786 1.351   27.737 1.00 9.06  ? 494 GLU A C      1 
ATOM   6534 O O      . GLU B 2 494 ? 45.699 0.950   27.303 1.00 8.63  ? 494 GLU A O      1 
ATOM   6535 C CB     . GLU B 2 494 ? 46.401 -0.058  29.750 1.00 18.19 ? 494 GLU A CB     1 
ATOM   6536 C CG     . GLU B 2 494 ? 46.989 -0.875  30.844 1.00 24.09 ? 494 GLU A CG     1 
ATOM   6537 C CD     . GLU B 2 494 ? 45.917 -1.496  31.679 1.00 26.72 ? 494 GLU A CD     1 
ATOM   6538 O OE1    . GLU B 2 494 ? 45.246 -2.423  31.171 1.00 28.46 ? 494 GLU A OE1    1 
ATOM   6539 O OE2    . GLU B 2 494 ? 45.716 -1.027  32.824 1.00 23.45 ? 494 GLU A OE2    1 
ATOM   6540 H H      . GLU B 2 494 ? 47.733 2.146   30.369 1.00 20.00 ? 494 GLU A H      1 
ATOM   6541 N N      . SER B 2 495 ? 47.392 2.437   27.248 1.00 6.80  ? 495 SER A N      1 
ATOM   6542 C CA     . SER B 2 495 ? 46.864 3.169   26.083 1.00 5.39  ? 495 SER A CA     1 
ATOM   6543 C C      . SER B 2 495 ? 46.911 2.275   24.840 1.00 5.31  ? 495 SER A C      1 
ATOM   6544 O O      . SER B 2 495 ? 46.142 2.476   23.905 1.00 4.64  ? 495 SER A O      1 
ATOM   6545 C CB     . SER B 2 495 ? 47.683 4.437   25.821 1.00 4.58  ? 495 SER A CB     1 
ATOM   6546 O OG     . SER B 2 495 ? 49.085 4.191   25.936 1.00 2.81  ? 495 SER A OG     1 
ATOM   6547 H H      . SER B 2 495 ? 48.242 2.735   27.638 1.00 20.00 ? 495 SER A H      1 
ATOM   6548 H HG     . SER B 2 495 ? 49.576 5.003   25.792 1.00 20.00 ? 495 SER A HG     1 
ATOM   6549 N N      . LEU B 2 496 ? 47.825 1.300   24.835 1.00 5.34  ? 496 LEU A N      1 
ATOM   6550 C CA     . LEU B 2 496 ? 47.975 0.362   23.719 1.00 4.79  ? 496 LEU A CA     1 
ATOM   6551 C C      . LEU B 2 496 ? 48.340 -1.021  24.232 1.00 7.67  ? 496 LEU A C      1 
ATOM   6552 O O      . LEU B 2 496 ? 49.375 -1.188  24.861 1.00 11.66 ? 496 LEU A O      1 
ATOM   6553 C CB     . LEU B 2 496 ? 49.083 0.825   22.759 1.00 3.58  ? 496 LEU A CB     1 
ATOM   6554 C CG     . LEU B 2 496 ? 49.628 -0.337  21.922 1.00 2.43  ? 496 LEU A CG     1 
ATOM   6555 C CD1    . LEU B 2 496 ? 48.559 -0.711  20.962 1.00 2.00  ? 496 LEU A CD1    1 
ATOM   6556 C CD2    . LEU B 2 496 ? 50.924 -0.022  21.186 1.00 2.01  ? 496 LEU A CD2    1 
ATOM   6557 H H      . LEU B 2 496 ? 48.428 1.216   25.602 1.00 20.00 ? 496 LEU A H      1 
ATOM   6558 N N      . VAL B 2 497 ? 47.500 -2.008  23.956 1.00 12.57 ? 497 VAL A N      1 
ATOM   6559 C CA     . VAL B 2 497 ? 47.772 -3.382  24.370 1.00 16.59 ? 497 VAL A CA     1 
ATOM   6560 C C      . VAL B 2 497 ? 47.635 -4.312  23.153 1.00 19.42 ? 497 VAL A C      1 
ATOM   6561 O O      . VAL B 2 497 ? 46.553 -4.498  22.563 1.00 18.85 ? 497 VAL A O      1 
ATOM   6562 C CB     . VAL B 2 497 ? 46.919 -3.834  25.602 1.00 18.03 ? 497 VAL A CB     1 
ATOM   6563 C CG1    . VAL B 2 497 ? 45.561 -3.118  25.626 1.00 17.39 ? 497 VAL A CG1    1 
ATOM   6564 C CG2    . VAL B 2 497 ? 46.734 -5.361  25.589 1.00 21.49 ? 497 VAL A CG2    1 
ATOM   6565 H H      . VAL B 2 497 ? 46.675 -1.801  23.489 1.00 20.00 ? 497 VAL A H      1 
ATOM   6566 N N      . ILE B 2 498 ? 48.786 -4.821  22.744 1.00 18.99 ? 498 ILE A N      1 
ATOM   6567 C CA     . ILE B 2 498 ? 48.906 -5.691  21.588 1.00 17.88 ? 498 ILE A CA     1 
ATOM   6568 C C      . ILE B 2 498 ? 48.532 -7.153  21.856 1.00 18.16 ? 498 ILE A C      1 
ATOM   6569 O O      . ILE B 2 498 ? 48.856 -7.710  22.902 1.00 19.63 ? 498 ILE A O      1 
ATOM   6570 C CB     . ILE B 2 498 ? 50.323 -5.600  21.048 1.00 15.97 ? 498 ILE A CB     1 
ATOM   6571 C CG1    . ILE B 2 498 ? 50.696 -4.136  20.862 1.00 11.74 ? 498 ILE A CG1    1 
ATOM   6572 C CG2    . ILE B 2 498 ? 50.445 -6.363  19.740 1.00 17.17 ? 498 ILE A CG2    1 
ATOM   6573 C CD1    . ILE B 2 498 ? 52.054 -3.951  20.324 1.00 13.92 ? 498 ILE A CD1    1 
ATOM   6574 H H      . ILE B 2 498 ? 49.584 -4.596  23.248 1.00 20.00 ? 498 ILE A H      1 
ATOM   6575 N N      . LYS B 2 499 ? 47.904 -7.781  20.873 1.00 20.78 ? 499 LYS A N      1 
ATOM   6576 C CA     . LYS B 2 499 ? 47.454 -9.159  20.975 1.00 23.31 ? 499 LYS A CA     1 
ATOM   6577 C C      . LYS B 2 499 ? 47.717 -9.884  19.676 1.00 24.04 ? 499 LYS A C      1 
ATOM   6578 O O      . LYS B 2 499 ? 47.960 -9.268  18.657 1.00 21.22 ? 499 LYS A O      1 
ATOM   6579 C CB     . LYS B 2 499 ? 45.946 -9.205  21.196 1.00 23.11 ? 499 LYS A CB     1 
ATOM   6580 C CG     . LYS B 2 499 ? 45.461 -8.588  22.470 1.00 25.64 ? 499 LYS A CG     1 
ATOM   6581 C CD     . LYS B 2 499 ? 45.822 -9.453  23.666 1.00 29.00 ? 499 LYS A CD     1 
ATOM   6582 C CE     . LYS B 2 499 ? 44.896 -9.191  24.871 1.00 31.07 ? 499 LYS A CE     1 
ATOM   6583 N NZ     . LYS B 2 499 ? 45.162 -10.136 25.995 1.00 32.03 ? 499 LYS A NZ     1 
ATOM   6584 H H      . LYS B 2 499 ? 47.775 -7.311  20.024 1.00 20.00 ? 499 LYS A H      1 
ATOM   6585 H HZ1    . LYS B 2 499 ? 46.189 -10.183 26.162 1.00 20.00 ? 499 LYS A HZ1    1 
ATOM   6586 H HZ2    . LYS B 2 499 ? 44.687 -9.796  26.851 1.00 20.00 ? 499 LYS A HZ2    1 
ATOM   6587 H HZ3    . LYS B 2 499 ? 44.811 -11.084 25.752 1.00 20.00 ? 499 LYS A HZ3    1 
ATOM   6588 N N      . GLN B 2 500 ? 47.719 -11.202 19.741 1.00 25.66 ? 500 GLN A N      1 
ATOM   6589 C CA     . GLN B 2 500 ? 47.894 -12.045 18.573 1.00 26.96 ? 500 GLN A CA     1 
ATOM   6590 C C      . GLN B 2 500 ? 46.606 -12.857 18.617 1.00 25.62 ? 500 GLN A C      1 
ATOM   6591 O O      . GLN B 2 500 ? 46.263 -13.424 19.655 1.00 26.16 ? 500 GLN A O      1 
ATOM   6592 C CB     . GLN B 2 500 ? 49.097 -12.959 18.755 1.00 29.58 ? 500 GLN A CB     1 
ATOM   6593 C CG     . GLN B 2 500 ? 50.361 -12.250 19.205 1.00 32.55 ? 500 GLN A CG     1 
ATOM   6594 C CD     . GLN B 2 500 ? 50.853 -11.226 18.202 1.00 33.25 ? 500 GLN A CD     1 
ATOM   6595 O OE1    . GLN B 2 500 ? 50.926 -11.508 17.003 1.00 34.26 ? 500 GLN A OE1    1 
ATOM   6596 N NE2    . GLN B 2 500 ? 51.182 -10.029 18.682 1.00 33.76 ? 500 GLN A NE2    1 
ATOM   6597 H H      . GLN B 2 500 ? 47.584 -11.637 20.602 1.00 20.00 ? 500 GLN A H      1 
ATOM   6598 H HE21   . GLN B 2 500 ? 51.469 -9.346  18.037 1.00 20.00 ? 500 GLN A HE21   1 
ATOM   6599 H HE22   . GLN B 2 500 ? 51.113 -9.861  19.640 1.00 20.00 ? 500 GLN A HE22   1 
ATOM   6600 N N      . GLY B 2 501 ? 45.835 -12.823 17.545 1.00 23.09 ? 501 GLY A N      1 
ATOM   6601 C CA     . GLY B 2 501 ? 44.587 -13.557 17.522 1.00 20.70 ? 501 GLY A CA     1 
ATOM   6602 C C      . GLY B 2 501 ? 44.428 -14.186 16.164 1.00 18.60 ? 501 GLY A C      1 
ATOM   6603 O O      . GLY B 2 501 ? 45.406 -14.321 15.423 1.00 18.50 ? 501 GLY A O      1 
ATOM   6604 H H      . GLY B 2 501 ? 46.101 -12.295 16.757 1.00 20.00 ? 501 GLY A H      1 
ATOM   6605 N N      . PHE B 2 502 ? 43.209 -14.579 15.832 1.00 18.01 ? 502 PHE A N      1 
ATOM   6606 C CA     . PHE B 2 502 ? 42.948 -15.193 14.547 1.00 18.74 ? 502 PHE A CA     1 
ATOM   6607 C C      . PHE B 2 502 ? 41.693 -14.577 13.955 1.00 19.08 ? 502 PHE A C      1 
ATOM   6608 O O      . PHE B 2 502 ? 40.783 -14.184 14.687 1.00 19.04 ? 502 PHE A O      1 
ATOM   6609 C CB     . PHE B 2 502 ? 42.751 -16.709 14.688 1.00 21.63 ? 502 PHE A CB     1 
ATOM   6610 C CG     . PHE B 2 502 ? 43.974 -17.447 15.185 1.00 25.02 ? 502 PHE A CG     1 
ATOM   6611 C CD1    . PHE B 2 502 ? 45.081 -17.630 14.362 1.00 26.46 ? 502 PHE A CD1    1 
ATOM   6612 C CD2    . PHE B 2 502 ? 44.023 -17.964 16.479 1.00 25.96 ? 502 PHE A CD2    1 
ATOM   6613 C CE1    . PHE B 2 502 ? 46.224 -18.309 14.832 1.00 26.29 ? 502 PHE A CE1    1 
ATOM   6614 C CE2    . PHE B 2 502 ? 45.163 -18.640 16.946 1.00 25.45 ? 502 PHE A CE2    1 
ATOM   6615 C CZ     . PHE B 2 502 ? 46.255 -18.811 16.118 1.00 24.90 ? 502 PHE A CZ     1 
ATOM   6616 H H      . PHE B 2 502 ? 42.472 -14.430 16.453 1.00 20.00 ? 502 PHE A H      1 
ATOM   6617 N N      . ALA B 2 503 ? 41.648 -14.492 12.626 1.00 18.53 ? 503 ALA A N      1 
ATOM   6618 C CA     . ALA B 2 503 ? 40.487 -13.939 11.938 1.00 15.01 ? 503 ALA A CA     1 
ATOM   6619 C C      . ALA B 2 503 ? 40.217 -14.774 10.712 1.00 15.76 ? 503 ALA A C      1 
ATOM   6620 O O      . ALA B 2 503 ? 41.144 -15.417 10.174 1.00 15.57 ? 503 ALA A O      1 
ATOM   6621 C CB     . ALA B 2 503 ? 40.762 -12.502 11.528 1.00 13.33 ? 503 ALA A CB     1 
ATOM   6622 H H      . ALA B 2 503 ? 42.421 -14.785 12.088 1.00 20.00 ? 503 ALA A H      1 
ATOM   6623 N N      . GLU B 2 504 ? 38.956 -14.803 10.289 1.00 17.15 ? 504 GLU A N      1 
ATOM   6624 C CA     . GLU B 2 504 ? 38.584 -15.543 9.098  1.00 20.27 ? 504 GLU A CA     1 
ATOM   6625 C C      . GLU B 2 504 ? 39.450 -15.045 7.938  1.00 22.52 ? 504 GLU A C      1 
ATOM   6626 O O      . GLU B 2 504 ? 39.746 -13.858 7.850  1.00 25.21 ? 504 GLU A O      1 
ATOM   6627 C CB     . GLU B 2 504 ? 37.111 -15.320 8.806  1.00 19.71 ? 504 GLU A CB     1 
ATOM   6628 C CG     . GLU B 2 504 ? 36.708 -13.895 8.562  1.00 17.88 ? 504 GLU A CG     1 
ATOM   6629 C CD     . GLU B 2 504 ? 35.322 -13.821 7.961  1.00 15.67 ? 504 GLU A CD     1 
ATOM   6630 O OE1    . GLU B 2 504 ? 35.190 -14.126 6.741  1.00 13.59 ? 504 GLU A OE1    1 
ATOM   6631 O OE2    . GLU B 2 504 ? 34.361 -13.502 8.700  1.00 11.66 ? 504 GLU A OE2    1 
ATOM   6632 H H      . GLU B 2 504 ? 38.277 -14.280 10.783 1.00 20.00 ? 504 GLU A H      1 
ATOM   6633 N N      . PRO B 2 505 ? 39.843 -15.932 7.010  1.00 25.94 ? 505 PRO A N      1 
ATOM   6634 C CA     . PRO B 2 505 ? 40.685 -15.600 5.850  1.00 26.65 ? 505 PRO A CA     1 
ATOM   6635 C C      . PRO B 2 505 ? 40.249 -14.486 4.873  1.00 26.96 ? 505 PRO A C      1 
ATOM   6636 O O      . PRO B 2 505 ? 41.055 -14.029 4.066  1.00 24.77 ? 505 PRO A O      1 
ATOM   6637 C CB     . PRO B 2 505 ? 40.835 -16.945 5.146  1.00 28.40 ? 505 PRO A CB     1 
ATOM   6638 C CG     . PRO B 2 505 ? 39.531 -17.580 5.396  1.00 29.82 ? 505 PRO A CG     1 
ATOM   6639 C CD     . PRO B 2 505 ? 39.315 -17.302 6.868  1.00 30.05 ? 505 PRO A CD     1 
ATOM   6640 N N      . SER B 2 506 ? 38.980 -14.079 4.907  1.00 24.11 ? 506 SER A N      1 
ATOM   6641 C CA     . SER B 2 506 ? 38.538 -13.021 4.004  1.00 22.77 ? 506 SER A CA     1 
ATOM   6642 C C      . SER B 2 506 ? 39.219 -11.705 4.377  1.00 20.45 ? 506 SER A C      1 
ATOM   6643 O O      . SER B 2 506 ? 39.475 -10.855 3.535  1.00 24.41 ? 506 SER A O      1 
ATOM   6644 C CB     . SER B 2 506 ? 37.010 -12.868 4.004  1.00 23.10 ? 506 SER A CB     1 
ATOM   6645 O OG     . SER B 2 506 ? 36.531 -12.249 5.172  1.00 22.86 ? 506 SER A OG     1 
ATOM   6646 H H      . SER B 2 506 ? 38.338 -14.491 5.508  1.00 20.00 ? 506 SER A H      1 
ATOM   6647 H HG     . SER B 2 506 ? 35.563 -12.166 5.078  1.00 20.00 ? 506 SER A HG     1 
ATOM   6648 N N      . LEU B 2 507 ? 39.601 -11.577 5.632  1.00 17.38 ? 507 LEU A N      1 
ATOM   6649 C CA     . LEU B 2 507 ? 40.280 -10.372 6.072  1.00 17.65 ? 507 LEU A CA     1 
ATOM   6650 C C      . LEU B 2 507 ? 41.647 -10.308 5.415  1.00 20.08 ? 507 LEU A C      1 
ATOM   6651 O O      . LEU B 2 507 ? 42.404 -9.372  5.632  1.00 23.50 ? 507 LEU A O      1 
ATOM   6652 C CB     . LEU B 2 507 ? 40.390 -10.320 7.598  1.00 16.91 ? 507 LEU A CB     1 
ATOM   6653 C CG     . LEU B 2 507 ? 39.223 -9.603  8.301  1.00 11.31 ? 507 LEU A CG     1 
ATOM   6654 C CD1    . LEU B 2 507 ? 37.850 -9.999  7.750  1.00 12.29 ? 507 LEU A CD1    1 
ATOM   6655 C CD2    . LEU B 2 507 ? 39.293 -9.884  9.782  1.00 11.01 ? 507 LEU A CD2    1 
ATOM   6656 H H      . LEU B 2 507 ? 39.431 -12.316 6.267  1.00 20.00 ? 507 LEU A H      1 
ATOM   6657 N N      . LYS B 2 508 ? 41.935 -11.291 4.576  1.00 24.18 ? 508 LYS A N      1 
ATOM   6658 C CA     . LYS B 2 508 ? 43.183 -11.352 3.842  1.00 28.06 ? 508 LYS A CA     1 
ATOM   6659 C C      . LYS B 2 508 ? 43.158 -10.195 2.844  1.00 29.67 ? 508 LYS A C      1 
ATOM   6660 O O      . LYS B 2 508 ? 44.208 -9.702  2.411  1.00 27.00 ? 508 LYS A O      1 
ATOM   6661 C CB     . LYS B 2 508 ? 43.253 -12.671 3.071  1.00 29.24 ? 508 LYS A CB     1 
ATOM   6662 C CG     . LYS B 2 508 ? 44.601 -13.018 2.513  1.00 32.09 ? 508 LYS A CG     1 
ATOM   6663 C CD     . LYS B 2 508 ? 45.359 -14.002 3.404  1.00 34.75 ? 508 LYS A CD     1 
ATOM   6664 C CE     . LYS B 2 508 ? 44.682 -15.383 3.478  1.00 36.51 ? 508 LYS A CE     1 
ATOM   6665 N NZ     . LYS B 2 508 ? 45.602 -16.451 4.007  1.00 36.86 ? 508 LYS A NZ     1 
ATOM   6666 H H      . LYS B 2 508 ? 41.323 -12.029 4.435  1.00 20.00 ? 508 LYS A H      1 
ATOM   6667 H HZ1    . LYS B 2 508 ? 46.101 -16.092 4.835  1.00 20.00 ? 508 LYS A HZ1    1 
ATOM   6668 H HZ2    . LYS B 2 508 ? 45.052 -17.294 4.240  1.00 20.00 ? 508 LYS A HZ2    1 
ATOM   6669 H HZ3    . LYS B 2 508 ? 46.301 -16.693 3.260  1.00 20.00 ? 508 LYS A HZ3    1 
ATOM   6670 N N      . ASP B 2 509 ? 41.956 -9.757  2.484  1.00 32.12 ? 509 ASP A N      1 
ATOM   6671 C CA     . ASP B 2 509 ? 41.803 -8.686  1.512  1.00 33.59 ? 509 ASP A CA     1 
ATOM   6672 C C      . ASP B 2 509 ? 41.398 -7.328  2.045  1.00 32.43 ? 509 ASP A C      1 
ATOM   6673 O O      . ASP B 2 509 ? 40.831 -6.522  1.318  1.00 32.46 ? 509 ASP A O      1 
ATOM   6674 C CB     . ASP B 2 509 ? 40.849 -9.113  0.403  1.00 36.85 ? 509 ASP A CB     1 
ATOM   6675 C CG     . ASP B 2 509 ? 41.406 -10.239 -0.435 1.00 36.74 ? 509 ASP A CG     1 
ATOM   6676 O OD1    . ASP B 2 509 ? 42.606 -10.166 -0.786 1.00 38.57 ? 509 ASP A OD1    1 
ATOM   6677 O OD2    . ASP B 2 509 ? 40.653 -11.191 -0.747 1.00 41.42 ? 509 ASP A OD2    1 
ATOM   6678 H H      . ASP B 2 509 ? 41.158 -10.170 2.861  1.00 20.00 ? 509 ASP A H      1 
ATOM   6679 N N      . ALA B 2 510 ? 41.659 -7.080  3.318  1.00 31.37 ? 510 ALA A N      1 
ATOM   6680 C CA     . ALA B 2 510 ? 41.329 -5.787  3.904  1.00 28.98 ? 510 ALA A CA     1 
ATOM   6681 C C      . ALA B 2 510 ? 42.325 -4.721  3.394  1.00 24.89 ? 510 ALA A C      1 
ATOM   6682 O O      . ALA B 2 510 ? 43.528 -4.999  3.239  1.00 25.72 ? 510 ALA A O      1 
ATOM   6683 C CB     . ALA B 2 510 ? 41.367 -5.879  5.439  1.00 30.68 ? 510 ALA A CB     1 
ATOM   6684 H H      . ALA B 2 510 ? 42.090 -7.748  3.878  1.00 20.00 ? 510 ALA A H      1 
ATOM   6685 N N      . VAL B 2 511 ? 41.816 -3.531  3.085  1.00 18.55 ? 511 VAL A N      1 
ATOM   6686 C CA     . VAL B 2 511 ? 42.662 -2.446  2.613  1.00 14.73 ? 511 VAL A CA     1 
ATOM   6687 C C      . VAL B 2 511 ? 42.913 -1.470  3.746  1.00 14.67 ? 511 VAL A C      1 
ATOM   6688 O O      . VAL B 2 511 ? 42.084 -1.318  4.655  1.00 15.00 ? 511 VAL A O      1 
ATOM   6689 C CB     . VAL B 2 511 ? 42.006 -1.675  1.441  1.00 13.30 ? 511 VAL A CB     1 
ATOM   6690 C CG1    . VAL B 2 511 ? 42.418 -2.288  0.092  1.00 13.95 ? 511 VAL A CG1    1 
ATOM   6691 C CG2    . VAL B 2 511 ? 40.475 -1.715  1.570  1.00 15.24 ? 511 VAL A CG2    1 
ATOM   6692 H H      . VAL B 2 511 ? 40.859 -3.374  3.204  1.00 20.00 ? 511 VAL A H      1 
ATOM   6693 N N      . ALA B 2 512 ? 44.076 -0.832  3.719  1.00 13.02 ? 512 ALA A N      1 
ATOM   6694 C CA     . ALA B 2 512 ? 44.408 0.158   4.746  1.00 10.88 ? 512 ALA A CA     1 
ATOM   6695 C C      . ALA B 2 512 ? 43.242 1.160   4.866  1.00 10.58 ? 512 ALA A C      1 
ATOM   6696 O O      . ALA B 2 512 ? 42.776 1.729   3.875  1.00 10.13 ? 512 ALA A O      1 
ATOM   6697 C CB     . ALA B 2 512 ? 45.715 0.870   4.387  1.00 8.35  ? 512 ALA A CB     1 
ATOM   6698 H H      . ALA B 2 512 ? 44.720 -1.038  3.019  1.00 20.00 ? 512 ALA A H      1 
ATOM   6699 N N      . GLY B 2 513 ? 42.728 1.301   6.080  1.00 14.70 ? 513 GLY A N      1 
ATOM   6700 C CA     . GLY B 2 513 ? 41.621 2.201   6.299  1.00 17.78 ? 513 GLY A CA     1 
ATOM   6701 C C      . GLY B 2 513 ? 40.372 1.766   5.541  1.00 22.43 ? 513 GLY A C      1 
ATOM   6702 O O      . GLY B 2 513 ? 40.076 2.253   4.442  1.00 22.90 ? 513 GLY A O      1 
ATOM   6703 H H      . GLY B 2 513 ? 43.113 0.774   6.824  1.00 20.00 ? 513 GLY A H      1 
ATOM   6704 N N      . LYS B 2 514 ? 39.651 0.826   6.143  1.00 27.36 ? 514 LYS A N      1 
ATOM   6705 C CA     . LYS B 2 514 ? 38.394 0.276   5.629  1.00 29.13 ? 514 LYS A CA     1 
ATOM   6706 C C      . LYS B 2 514 ? 37.901 -0.482  6.860  1.00 28.49 ? 514 LYS A C      1 
ATOM   6707 O O      . LYS B 2 514 ? 38.274 -1.629  7.102  1.00 29.24 ? 514 LYS A O      1 
ATOM   6708 C CB     . LYS B 2 514 ? 38.659 -0.685  4.472  1.00 31.75 ? 514 LYS A CB     1 
ATOM   6709 C CG     . LYS B 2 514 ? 37.418 -1.066  3.651  1.00 35.19 ? 514 LYS A CG     1 
ATOM   6710 C CD     . LYS B 2 514 ? 36.483 -2.025  4.409  1.00 34.71 ? 514 LYS A CD     1 
ATOM   6711 C CE     . LYS B 2 514 ? 35.779 -3.034  3.495  1.00 33.85 ? 514 LYS A CE     1 
ATOM   6712 N NZ     . LYS B 2 514 ? 36.706 -3.992  2.805  1.00 31.85 ? 514 LYS A NZ     1 
ATOM   6713 H H      . LYS B 2 514 ? 40.017 0.431   6.967  1.00 20.00 ? 514 LYS A H      1 
ATOM   6714 H HZ1    . LYS B 2 514 ? 37.374 -4.381  3.482  1.00 20.00 ? 514 LYS A HZ1    1 
ATOM   6715 H HZ2    . LYS B 2 514 ? 36.146 -4.765  2.375  1.00 20.00 ? 514 LYS A HZ2    1 
ATOM   6716 H HZ3    . LYS B 2 514 ? 37.236 -3.516  2.030  1.00 20.00 ? 514 LYS A HZ3    1 
ATOM   6717 N N      . ALA B 2 515 ? 37.173 0.223   7.709  1.00 27.53 ? 515 ALA A N      1 
ATOM   6718 C CA     . ALA B 2 515 ? 36.707 -0.360  8.950  1.00 28.75 ? 515 ALA A CA     1 
ATOM   6719 C C      . ALA B 2 515 ? 35.731 -1.500  8.820  1.00 28.39 ? 515 ALA A C      1 
ATOM   6720 O O      . ALA B 2 515 ? 34.741 -1.403  8.091  1.00 27.68 ? 515 ALA A O      1 
ATOM   6721 C CB     . ALA B 2 515 ? 36.131 0.718   9.859  1.00 31.37 ? 515 ALA A CB     1 
ATOM   6722 H H      . ALA B 2 515 ? 36.928 1.152   7.489  1.00 20.00 ? 515 ALA A H      1 
ATOM   6723 N N      . PHE B 2 516 ? 36.064 -2.589  9.516  1.00 27.41 ? 516 PHE A N      1 
ATOM   6724 C CA     . PHE B 2 516 ? 35.237 -3.796  9.599  1.00 23.33 ? 516 PHE A CA     1 
ATOM   6725 C C      . PHE B 2 516 ? 34.726 -3.811  11.040 1.00 21.38 ? 516 PHE A C      1 
ATOM   6726 O O      . PHE B 2 516 ? 35.334 -3.198  11.933 1.00 20.82 ? 516 PHE A O      1 
ATOM   6727 C CB     . PHE B 2 516 ? 36.077 -5.065  9.420  1.00 22.86 ? 516 PHE A CB     1 
ATOM   6728 C CG     . PHE B 2 516 ? 36.608 -5.257  8.038  1.00 24.94 ? 516 PHE A CG     1 
ATOM   6729 C CD1    . PHE B 2 516 ? 35.828 -5.825  7.061  1.00 24.08 ? 516 PHE A CD1    1 
ATOM   6730 C CD2    . PHE B 2 516 ? 37.898 -4.870  7.713  1.00 26.09 ? 516 PHE A CD2    1 
ATOM   6731 C CE1    . PHE B 2 516 ? 36.326 -6.006  5.775  1.00 25.22 ? 516 PHE A CE1    1 
ATOM   6732 C CE2    . PHE B 2 516 ? 38.396 -5.049  6.435  1.00 26.64 ? 516 PHE A CE2    1 
ATOM   6733 C CZ     . PHE B 2 516 ? 37.609 -5.616  5.467  1.00 25.24 ? 516 PHE A CZ     1 
ATOM   6734 H H      . PHE B 2 516 ? 36.897 -2.555  10.033 1.00 20.00 ? 516 PHE A H      1 
ATOM   6735 N N      . GLN B 2 517 ? 33.615 -4.500  11.263 1.00 20.39 ? 517 GLN A N      1 
ATOM   6736 C CA     . GLN B 2 517 ? 33.060 -4.620  12.606 1.00 17.78 ? 517 GLN A CA     1 
ATOM   6737 C C      . GLN B 2 517 ? 33.286 -6.052  13.064 1.00 16.74 ? 517 GLN A C      1 
ATOM   6738 O O      . GLN B 2 517 ? 32.509 -6.914  12.667 1.00 16.46 ? 517 GLN A O      1 
ATOM   6739 C CB     . GLN B 2 517 ? 31.556 -4.366  12.610 1.00 13.37 ? 517 GLN A CB     1 
ATOM   6740 C CG     . GLN B 2 517 ? 31.024 -4.023  13.977 1.00 12.54 ? 517 GLN A CG     1 
ATOM   6741 C CD     . GLN B 2 517 ? 29.759 -4.765  14.330 1.00 7.96  ? 517 GLN A CD     1 
ATOM   6742 O OE1    . GLN B 2 517 ? 29.774 -5.974  14.513 1.00 7.58  ? 517 GLN A OE1    1 
ATOM   6743 N NE2    . GLN B 2 517 ? 28.650 -4.035  14.454 1.00 7.35  ? 517 GLN A NE2    1 
ATOM   6744 H H      . GLN B 2 517 ? 33.173 -4.945  10.516 1.00 20.00 ? 517 GLN A H      1 
ATOM   6745 H HE21   . GLN B 2 517 ? 27.816 -4.509  14.644 1.00 20.00 ? 517 GLN A HE21   1 
ATOM   6746 H HE22   . GLN B 2 517 ? 28.672 -3.068  14.295 1.00 20.00 ? 517 GLN A HE22   1 
ATOM   6747 N N      . PHE B 2 518 ? 34.409 -6.336  13.734 1.00 13.83 ? 518 PHE A N      1 
ATOM   6748 C CA     . PHE B 2 518 ? 34.682 -7.682  14.247 1.00 12.11 ? 518 PHE A CA     1 
ATOM   6749 C C      . PHE B 2 518 ? 33.513 -7.901  15.184 1.00 15.47 ? 518 PHE A C      1 
ATOM   6750 O O      . PHE B 2 518 ? 33.368 -7.168  16.158 1.00 15.73 ? 518 PHE A O      1 
ATOM   6751 C CB     . PHE B 2 518 ? 36.014 -7.744  15.003 1.00 6.48  ? 518 PHE A CB     1 
ATOM   6752 C CG     . PHE B 2 518 ? 37.207 -7.683  14.111 1.00 2.51  ? 518 PHE A CG     1 
ATOM   6753 C CD1    . PHE B 2 518 ? 37.053 -7.552  12.733 1.00 2.00  ? 518 PHE A CD1    1 
ATOM   6754 C CD2    . PHE B 2 518 ? 38.486 -7.777  14.637 1.00 2.00  ? 518 PHE A CD2    1 
ATOM   6755 C CE1    . PHE B 2 518 ? 38.163 -7.519  11.901 1.00 2.00  ? 518 PHE A CE1    1 
ATOM   6756 C CE2    . PHE B 2 518 ? 39.614 -7.746  13.808 1.00 2.01  ? 518 PHE A CE2    1 
ATOM   6757 C CZ     . PHE B 2 518 ? 39.462 -7.617  12.441 1.00 2.01  ? 518 PHE A CZ     1 
ATOM   6758 H H      . PHE B 2 518 ? 35.053 -5.617  13.937 1.00 20.00 ? 518 PHE A H      1 
ATOM   6759 N N      . GLU B 2 519 ? 32.609 -8.799  14.791 1.00 18.52 ? 519 GLU A N      1 
ATOM   6760 C CA     . GLU B 2 519 ? 31.389 -9.094  15.538 1.00 21.04 ? 519 GLU A CA     1 
ATOM   6761 C C      . GLU B 2 519 ? 31.623 -9.286  17.014 1.00 21.39 ? 519 GLU A C      1 
ATOM   6762 O O      . GLU B 2 519 ? 32.507 -10.048 17.402 1.00 19.95 ? 519 GLU A O      1 
ATOM   6763 C CB     . GLU B 2 519 ? 30.710 -10.335 14.962 1.00 23.69 ? 519 GLU A CB     1 
ATOM   6764 C CG     . GLU B 2 519 ? 30.270 -10.174 13.528 1.00 23.90 ? 519 GLU A CG     1 
ATOM   6765 C CD     . GLU B 2 519 ? 28.789 -10.446 13.341 1.00 23.47 ? 519 GLU A CD     1 
ATOM   6766 O OE1    . GLU B 2 519 ? 27.956 -9.709  13.927 1.00 24.26 ? 519 GLU A OE1    1 
ATOM   6767 O OE2    . GLU B 2 519 ? 28.469 -11.401 12.598 1.00 21.40 ? 519 GLU A OE2    1 
ATOM   6768 H H      . GLU B 2 519 ? 32.756 -9.270  13.948 1.00 20.00 ? 519 GLU A H      1 
ATOM   6769 N N      . ARG B 2 520 ? 30.833 -8.580  17.828 1.00 24.41 ? 520 ARG A N      1 
ATOM   6770 C CA     . ARG B 2 520 ? 30.901 -8.641  19.292 1.00 24.79 ? 520 ARG A CA     1 
ATOM   6771 C C      . ARG B 2 520 ? 32.146 -8.069  19.974 1.00 25.45 ? 520 ARG A C      1 
ATOM   6772 O O      . ARG B 2 520 ? 32.303 -8.226  21.170 1.00 27.88 ? 520 ARG A O      1 
ATOM   6773 C CB     . ARG B 2 520 ? 30.662 -10.066 19.791 1.00 27.47 ? 520 ARG A CB     1 
ATOM   6774 C CG     . ARG B 2 520 ? 29.506 -10.770 19.102 1.00 31.00 ? 520 ARG A CG     1 
ATOM   6775 C CD     . ARG B 2 520 ? 28.809 -11.711 20.043 1.00 32.33 ? 520 ARG A CD     1 
ATOM   6776 N NE     . ARG B 2 520 ? 29.761 -12.480 20.827 1.00 33.94 ? 520 ARG A NE     1 
ATOM   6777 C CZ     . ARG B 2 520 ? 29.594 -12.783 22.110 1.00 34.31 ? 520 ARG A CZ     1 
ATOM   6778 N NH1    . ARG B 2 520 ? 28.509 -12.381 22.774 1.00 37.99 ? 520 ARG A NH1    1 
ATOM   6779 N NH2    . ARG B 2 520 ? 30.518 -13.495 22.734 1.00 36.51 ? 520 ARG A NH2    1 
ATOM   6780 H H      . ARG B 2 520 ? 30.158 -7.999  17.414 1.00 20.00 ? 520 ARG A H      1 
ATOM   6781 H HE     . ARG B 2 520 ? 30.571 -12.782 20.372 1.00 20.00 ? 520 ARG A HE     1 
ATOM   6782 H HH11   . ARG B 2 520 ? 27.796 -11.855 22.306 1.00 20.00 ? 520 ARG A HH11   1 
ATOM   6783 H HH12   . ARG B 2 520 ? 28.393 -12.625 23.736 1.00 20.00 ? 520 ARG A HH12   1 
ATOM   6784 H HH21   . ARG B 2 520 ? 31.332 -13.792 22.227 1.00 20.00 ? 520 ARG A HH21   1 
ATOM   6785 H HH22   . ARG B 2 520 ? 30.409 -13.729 23.691 1.00 20.00 ? 520 ARG A HH22   1 
ATOM   6786 N N      . GLU B 2 521 ? 33.058 -7.477  19.219 1.00 30.32 ? 521 GLU A N      1 
ATOM   6787 C CA     . GLU B 2 521 ? 34.255 -6.872  19.807 1.00 29.85 ? 521 GLU A CA     1 
ATOM   6788 C C      . GLU B 2 521 ? 34.149 -5.384  19.537 1.00 25.77 ? 521 GLU A C      1 
ATOM   6789 O O      . GLU B 2 521 ? 33.548 -4.665  20.321 1.00 26.55 ? 521 GLU A O      1 
ATOM   6790 C CB     . GLU B 2 521 ? 35.539 -7.431  19.190 1.00 34.09 ? 521 GLU A CB     1 
ATOM   6791 C CG     . GLU B 2 521 ? 35.769 -8.903  19.464 1.00 35.98 ? 521 GLU A CG     1 
ATOM   6792 C CD     . GLU B 2 521 ? 36.136 -9.210  20.901 1.00 38.51 ? 521 GLU A CD     1 
ATOM   6793 O OE1    . GLU B 2 521 ? 36.406 -8.286  21.699 1.00 38.92 ? 521 GLU A OE1    1 
ATOM   6794 O OE2    . GLU B 2 521 ? 36.167 -10.409 21.229 1.00 38.42 ? 521 GLU A OE2    1 
ATOM   6795 H H      . GLU B 2 521 ? 32.959 -7.474  18.235 1.00 20.00 ? 521 GLU A H      1 
ATOM   6796 N N      . GLY B 2 522 ? 34.666 -4.939  18.399 1.00 21.79 ? 522 GLY A N      1 
ATOM   6797 C CA     . GLY B 2 522 ? 34.582 -3.534  18.051 1.00 19.15 ? 522 GLY A CA     1 
ATOM   6798 C C      . GLY B 2 522 ? 34.922 -3.312  16.594 1.00 15.78 ? 522 GLY A C      1 
ATOM   6799 O O      . GLY B 2 522 ? 35.190 -4.265  15.885 1.00 16.62 ? 522 GLY A O      1 
ATOM   6800 H H      . GLY B 2 522 ? 35.093 -5.537  17.758 1.00 20.00 ? 522 GLY A H      1 
ATOM   6801 N N      . TYR B 2 523 ? 34.833 -2.080  16.115 1.00 12.89 ? 523 TYR A N      1 
ATOM   6802 C CA     . TYR B 2 523 ? 35.176 -1.809  14.730 1.00 8.48  ? 523 TYR A CA     1 
ATOM   6803 C C      . TYR B 2 523 ? 36.701 -1.744  14.704 1.00 8.83  ? 523 TYR A C      1 
ATOM   6804 O O      . TYR B 2 523 ? 37.320 -1.087  15.565 1.00 11.05 ? 523 TYR A O      1 
ATOM   6805 C CB     . TYR B 2 523 ? 34.587 -0.487  14.294 1.00 5.09  ? 523 TYR A CB     1 
ATOM   6806 C CG     . TYR B 2 523 ? 33.120 -0.412  14.536 1.00 3.48  ? 523 TYR A CG     1 
ATOM   6807 C CD1    . TYR B 2 523 ? 32.631 -0.174  15.798 1.00 4.76  ? 523 TYR A CD1    1 
ATOM   6808 C CD2    . TYR B 2 523 ? 32.211 -0.600  13.506 1.00 4.44  ? 523 TYR A CD2    1 
ATOM   6809 C CE1    . TYR B 2 523 ? 31.270 -0.124  16.040 1.00 3.92  ? 523 TYR A CE1    1 
ATOM   6810 C CE2    . TYR B 2 523 ? 30.828 -0.555  13.735 1.00 3.16  ? 523 TYR A CE2    1 
ATOM   6811 C CZ     . TYR B 2 523 ? 30.372 -0.316  15.011 1.00 2.42  ? 523 TYR A CZ     1 
ATOM   6812 O OH     . TYR B 2 523 ? 29.020 -0.283  15.298 1.00 6.91  ? 523 TYR A OH     1 
ATOM   6813 H H      . TYR B 2 523 ? 34.634 -1.328  16.725 1.00 20.00 ? 523 TYR A H      1 
ATOM   6814 H HH     . TYR B 2 523 ? 28.529 -0.465  14.496 1.00 20.00 ? 523 TYR A HH     1 
ATOM   6815 N N      . PHE B 2 524 ? 37.297 -2.469  13.764 1.00 7.07  ? 524 PHE A N      1 
ATOM   6816 C CA     . PHE B 2 524 ? 38.735 -2.503  13.634 1.00 7.37  ? 524 PHE A CA     1 
ATOM   6817 C C      . PHE B 2 524 ? 39.067 -2.053  12.220 1.00 8.58  ? 524 PHE A C      1 
ATOM   6818 O O      . PHE B 2 524 ? 38.185 -2.001  11.369 1.00 10.70 ? 524 PHE A O      1 
ATOM   6819 C CB     . PHE B 2 524 ? 39.273 -3.929  13.876 1.00 9.11  ? 524 PHE A CB     1 
ATOM   6820 C CG     . PHE B 2 524 ? 39.124 -4.431  15.317 1.00 14.10 ? 524 PHE A CG     1 
ATOM   6821 C CD1    . PHE B 2 524 ? 37.876 -4.484  15.939 1.00 16.04 ? 524 PHE A CD1    1 
ATOM   6822 C CD2    . PHE B 2 524 ? 40.244 -4.874  16.042 1.00 16.76 ? 524 PHE A CD2    1 
ATOM   6823 C CE1    . PHE B 2 524 ? 37.737 -4.956  17.241 1.00 17.08 ? 524 PHE A CE1    1 
ATOM   6824 C CE2    . PHE B 2 524 ? 40.106 -5.352  17.350 1.00 16.27 ? 524 PHE A CE2    1 
ATOM   6825 C CZ     . PHE B 2 524 ? 38.852 -5.393  17.943 1.00 16.63 ? 524 PHE A CZ     1 
ATOM   6826 H H      . PHE B 2 524 ? 36.768 -2.972  13.133 1.00 20.00 ? 524 PHE A H      1 
ATOM   6827 N N      . CYS B 2 525 ? 40.329 -1.714  11.965 1.00 8.70  ? 525 CYS A N      1 
ATOM   6828 C CA     . CYS B 2 525 ? 40.748 -1.316  10.626 1.00 5.15  ? 525 CYS A CA     1 
ATOM   6829 C C      . CYS B 2 525 ? 42.235 -1.652  10.440 1.00 2.88  ? 525 CYS A C      1 
ATOM   6830 O O      . CYS B 2 525 ? 42.998 -1.626  11.398 1.00 3.01  ? 525 CYS A O      1 
ATOM   6831 C CB     . CYS B 2 525 ? 40.450 0.161   10.402 1.00 5.65  ? 525 CYS A CB     1 
ATOM   6832 S SG     . CYS B 2 525 ? 41.711 1.298   10.901 1.00 7.46  ? 525 CYS A SG     1 
ATOM   6833 H H      . CYS B 2 525 ? 41.008 -1.737  12.703 1.00 20.00 ? 525 CYS A H      1 
ATOM   6834 N N      . LEU B 2 526 ? 42.630 -2.040  9.231  1.00 3.47  ? 526 LEU A N      1 
ATOM   6835 C CA     . LEU B 2 526 ? 44.010 -2.426  8.970  1.00 8.32  ? 526 LEU A CA     1 
ATOM   6836 C C      . LEU B 2 526 ? 44.942 -1.247  9.164  1.00 11.44 ? 526 LEU A C      1 
ATOM   6837 O O      . LEU B 2 526 ? 44.713 -0.179  8.620  1.00 14.15 ? 526 LEU A O      1 
ATOM   6838 C CB     . LEU B 2 526 ? 44.150 -2.995  7.541  1.00 9.87  ? 526 LEU A CB     1 
ATOM   6839 C CG     . LEU B 2 526 ? 45.477 -3.692  7.152  1.00 10.23 ? 526 LEU A CG     1 
ATOM   6840 C CD1    . LEU B 2 526 ? 45.563 -5.022  7.896  1.00 6.63  ? 526 LEU A CD1    1 
ATOM   6841 C CD2    . LEU B 2 526 ? 45.569 -3.947  5.635  1.00 8.68  ? 526 LEU A CD2    1 
ATOM   6842 H H      . LEU B 2 526 ? 41.990 -2.058  8.506  1.00 20.00 ? 526 LEU A H      1 
ATOM   6843 N N      . ASP B 2 527 ? 45.951 -1.415  9.993  1.00 16.60 ? 527 ASP A N      1 
ATOM   6844 C CA     . ASP B 2 527 ? 46.914 -0.361  10.248 1.00 25.39 ? 527 ASP A CA     1 
ATOM   6845 C C      . ASP B 2 527 ? 47.870 -0.330  9.063  1.00 29.46 ? 527 ASP A C      1 
ATOM   6846 O O      . ASP B 2 527 ? 48.578 -1.296  8.826  1.00 27.64 ? 527 ASP A O      1 
ATOM   6847 C CB     . ASP B 2 527 ? 47.686 -0.677  11.537 1.00 26.14 ? 527 ASP A CB     1 
ATOM   6848 C CG     . ASP B 2 527 ? 48.706 0.377   11.890 1.00 26.34 ? 527 ASP A CG     1 
ATOM   6849 O OD1    . ASP B 2 527 ? 49.714 0.546   11.153 1.00 25.81 ? 527 ASP A OD1    1 
ATOM   6850 O OD2    . ASP B 2 527 ? 48.509 1.008   12.942 1.00 22.95 ? 527 ASP A OD2    1 
ATOM   6851 H H      . ASP B 2 527 ? 46.014 -2.226  10.483 1.00 20.00 ? 527 ASP A H      1 
ATOM   6852 N N      . SER B 2 528 ? 47.920 0.790   8.351  1.00 35.14 ? 528 SER A N      1 
ATOM   6853 C CA     . SER B 2 528 ? 48.807 0.888   7.198  1.00 40.16 ? 528 SER A CA     1 
ATOM   6854 C C      . SER B 2 528 ? 50.224 0.642   7.674  1.00 40.53 ? 528 SER A C      1 
ATOM   6855 O O      . SER B 2 528 ? 50.772 -0.448  7.508  1.00 40.90 ? 528 SER A O      1 
ATOM   6856 C CB     . SER B 2 528 ? 48.712 2.278   6.556  1.00 43.15 ? 528 SER A CB     1 
ATOM   6857 O OG     . SER B 2 528 ? 49.502 2.350   5.377  1.00 48.86 ? 528 SER A OG     1 
ATOM   6858 H H      . SER B 2 528 ? 47.361 1.563   8.596  1.00 20.00 ? 528 SER A H      1 
ATOM   6859 H HG     . SER B 2 528 ? 49.472 3.224   4.984  1.00 20.00 ? 528 SER A HG     1 
ATOM   6860 N N      . ARG B 2 529 ? 50.757 1.642   8.361  1.00 40.44 ? 529 ARG A N      1 
ATOM   6861 C CA     . ARG B 2 529 ? 52.110 1.638   8.903  1.00 36.98 ? 529 ARG A CA     1 
ATOM   6862 C C      . ARG B 2 529 ? 52.727 0.298   9.322  1.00 31.77 ? 529 ARG A C      1 
ATOM   6863 O O      . ARG B 2 529 ? 53.933 0.098   9.175  1.00 31.42 ? 529 ARG A O      1 
ATOM   6864 C CB     . ARG B 2 529 ? 52.163 2.602   10.083 1.00 39.82 ? 529 ARG A CB     1 
ATOM   6865 C CG     . ARG B 2 529 ? 53.489 2.638   10.791 1.00 42.06 ? 529 ARG A CG     1 
ATOM   6866 C CD     . ARG B 2 529 ? 54.046 4.038   10.803 1.00 46.76 ? 529 ARG A CD     1 
ATOM   6867 N NE     . ARG B 2 529 ? 54.048 4.629   9.466  1.00 49.41 ? 529 ARG A NE     1 
ATOM   6868 C CZ     . ARG B 2 529 ? 53.534 5.821   9.186  1.00 52.58 ? 529 ARG A CZ     1 
ATOM   6869 N NH1    . ARG B 2 529 ? 52.971 6.546   10.146 1.00 51.99 ? 529 ARG A NH1    1 
ATOM   6870 N NH2    . ARG B 2 529 ? 53.600 6.293   7.947  1.00 50.78 ? 529 ARG A NH2    1 
ATOM   6871 H H      . ARG B 2 529 ? 50.232 2.444   8.493  1.00 20.00 ? 529 ARG A H      1 
ATOM   6872 H HE     . ARG B 2 529 ? 54.454 4.116   8.730  1.00 20.00 ? 529 ARG A HE     1 
ATOM   6873 H HH11   . ARG B 2 529 ? 52.949 6.196   11.083 1.00 20.00 ? 529 ARG A HH11   1 
ATOM   6874 H HH12   . ARG B 2 529 ? 52.591 7.442   9.933  1.00 20.00 ? 529 ARG A HH12   1 
ATOM   6875 H HH21   . ARG B 2 529 ? 54.019 5.743   7.223  1.00 20.00 ? 529 ARG A HH21   1 
ATOM   6876 H HH22   . ARG B 2 529 ? 53.202 7.183   7.731  1.00 20.00 ? 529 ARG A HH22   1 
ATOM   6877 N N      . HIS B 2 530 ? 51.921 -0.595  9.885  1.00 28.10 ? 530 HIS A N      1 
ATOM   6878 C CA     . HIS B 2 530 ? 52.445 -1.864  10.370 1.00 25.79 ? 530 HIS A CA     1 
ATOM   6879 C C      . HIS B 2 530 ? 52.161 -3.166  9.636  1.00 24.07 ? 530 HIS A C      1 
ATOM   6880 O O      . HIS B 2 530 ? 52.974 -4.087  9.685  1.00 22.76 ? 530 HIS A O      1 
ATOM   6881 C CB     . HIS B 2 530 ? 52.046 -2.029  11.816 1.00 27.35 ? 530 HIS A CB     1 
ATOM   6882 C CG     . HIS B 2 530 ? 52.724 -1.069  12.730 1.00 30.50 ? 530 HIS A CG     1 
ATOM   6883 N ND1    . HIS B 2 530 ? 54.063 -0.739  12.607 1.00 32.25 ? 530 HIS A ND1    1 
ATOM   6884 C CD2    . HIS B 2 530 ? 52.278 -0.411  13.830 1.00 30.55 ? 530 HIS A CD2    1 
ATOM   6885 C CE1    . HIS B 2 530 ? 54.408 0.063   13.591 1.00 31.52 ? 530 HIS A CE1    1 
ATOM   6886 N NE2    . HIS B 2 530 ? 53.344 0.280   14.352 1.00 31.89 ? 530 HIS A NE2    1 
ATOM   6887 H H      . HIS B 2 530 ? 50.959 -0.446  9.875  1.00 20.00 ? 530 HIS A H      1 
ATOM   6888 H HD1    . HIS B 2 530 ? 54.670 -1.048  11.875 1.00 20.00 ? 530 HIS A HD1    1 
ATOM   6889 H HE2    . HIS B 2 530 ? 53.324 0.817   15.167 1.00 20.00 ? 530 HIS A HE2    1 
ATOM   6890 N N      . SER B 2 531 ? 50.969 -3.290  9.066  1.00 24.01 ? 531 SER A N      1 
ATOM   6891 C CA     . SER B 2 531 ? 50.591 -4.499  8.371  1.00 24.48 ? 531 SER A CA     1 
ATOM   6892 C C      . SER B 2 531 ? 51.572 -4.906  7.284  1.00 29.74 ? 531 SER A C      1 
ATOM   6893 O O      . SER B 2 531 ? 52.357 -4.087  6.799  1.00 29.77 ? 531 SER A O      1 
ATOM   6894 C CB     . SER B 2 531 ? 49.202 -4.337  7.779  1.00 20.69 ? 531 SER A CB     1 
ATOM   6895 O OG     . SER B 2 531 ? 48.259 -4.212  8.817  1.00 19.16 ? 531 SER A OG     1 
ATOM   6896 H H      . SER B 2 531 ? 50.339 -2.544  9.080  1.00 20.00 ? 531 SER A H      1 
ATOM   6897 H HG     . SER B 2 531 ? 47.445 -4.065  8.420  1.00 20.00 ? 531 SER A HG     1 
ATOM   6898 N N      . THR B 2 532 ? 51.587 -6.199  6.974  1.00 34.62 ? 532 THR A N      1 
ATOM   6899 C CA     . THR B 2 532 ? 52.432 -6.737  5.916  1.00 40.67 ? 532 THR A CA     1 
ATOM   6900 C C      . THR B 2 532 ? 51.609 -7.833  5.263  1.00 43.46 ? 532 THR A C      1 
ATOM   6901 O O      . THR B 2 532 ? 50.407 -7.976  5.541  1.00 44.84 ? 532 THR A O      1 
ATOM   6902 C CB     . THR B 2 532 ? 53.765 -7.379  6.418  1.00 43.43 ? 532 THR A CB     1 
ATOM   6903 O OG1    . THR B 2 532 ? 53.500 -8.660  7.015  1.00 43.15 ? 532 THR A OG1    1 
ATOM   6904 C CG2    . THR B 2 532 ? 54.513 -6.455  7.383  1.00 46.24 ? 532 THR A CG2    1 
ATOM   6905 H H      . THR B 2 532 ? 51.009 -6.816  7.465  1.00 20.00 ? 532 THR A H      1 
ATOM   6906 H HG1    . THR B 2 532 ? 54.332 -9.022  7.340  1.00 20.00 ? 532 THR A HG1    1 
ATOM   6907 N N      . ALA B 2 533 ? 52.289 -8.654  4.465  1.00 44.94 ? 533 ALA A N      1 
ATOM   6908 C CA     . ALA B 2 533 ? 51.665 -9.754  3.742  1.00 43.99 ? 533 ALA A CA     1 
ATOM   6909 C C      . ALA B 2 533 ? 51.160 -10.881 4.635  1.00 45.01 ? 533 ALA A C      1 
ATOM   6910 O O      . ALA B 2 533 ? 49.964 -11.183 4.624  1.00 45.31 ? 533 ALA A O      1 
ATOM   6911 C CB     . ALA B 2 533 ? 52.629 -10.291 2.693  1.00 41.10 ? 533 ALA A CB     1 
ATOM   6912 H H      . ALA B 2 533 ? 53.237 -8.496  4.345  1.00 20.00 ? 533 ALA A H      1 
ATOM   6913 N N      . GLU B 2 534 ? 52.056 -11.518 5.392  1.00 45.91 ? 534 GLU A N      1 
ATOM   6914 C CA     . GLU B 2 534 ? 51.629 -12.614 6.264  1.00 48.00 ? 534 GLU A CA     1 
ATOM   6915 C C      . GLU B 2 534 ? 50.915 -12.054 7.474  1.00 46.02 ? 534 GLU A C      1 
ATOM   6916 O O      . GLU B 2 534 ? 49.774 -12.436 7.769  1.00 44.57 ? 534 GLU A O      1 
ATOM   6917 C CB     . GLU B 2 534 ? 52.808 -13.472 6.759  1.00 53.06 ? 534 GLU A CB     1 
ATOM   6918 C CG     . GLU B 2 534 ? 52.409 -14.871 7.370  1.00 59.99 ? 534 GLU A CG     1 
ATOM   6919 C CD     . GLU B 2 534 ? 51.484 -14.827 8.619  1.00 65.32 ? 534 GLU A CD     1 
ATOM   6920 O OE1    . GLU B 2 534 ? 51.963 -14.530 9.747  1.00 66.61 ? 534 GLU A OE1    1 
ATOM   6921 O OE2    . GLU B 2 534 ? 50.274 -15.124 8.458  1.00 65.77 ? 534 GLU A OE2    1 
ATOM   6922 H H      . GLU B 2 534 ? 52.996 -11.246 5.371  1.00 20.00 ? 534 GLU A H      1 
ATOM   6923 N N      . LYS B 2 535 ? 51.609 -11.173 8.190  1.00 40.77 ? 535 LYS A N      1 
ATOM   6924 C CA     . LYS B 2 535 ? 51.076 -10.586 9.405  1.00 34.36 ? 535 LYS A CA     1 
ATOM   6925 C C      . LYS B 2 535 ? 50.362 -9.237  9.256  1.00 32.68 ? 535 LYS A C      1 
ATOM   6926 O O      . LYS B 2 535 ? 50.997 -8.174  9.186  1.00 32.69 ? 535 LYS A O      1 
ATOM   6927 C CB     . LYS B 2 535 ? 52.198 -10.478 10.434 1.00 34.56 ? 535 LYS A CB     1 
ATOM   6928 C CG     . LYS B 2 535 ? 51.751 -10.205 11.859 1.00 35.64 ? 535 LYS A CG     1 
ATOM   6929 C CD     . LYS B 2 535 ? 51.153 -11.441 12.521 1.00 36.62 ? 535 LYS A CD     1 
ATOM   6930 C CE     . LYS B 2 535 ? 51.480 -11.471 14.014 1.00 36.60 ? 535 LYS A CE     1 
ATOM   6931 N NZ     . LYS B 2 535 ? 50.946 -12.685 14.708 1.00 34.32 ? 535 LYS A NZ     1 
ATOM   6932 H H      . LYS B 2 535 ? 52.475 -10.862 7.860  1.00 20.00 ? 535 LYS A H      1 
ATOM   6933 H HZ1    . LYS B 2 535 ? 51.175 -13.519 14.145 1.00 20.00 ? 535 LYS A HZ1    1 
ATOM   6934 H HZ2    . LYS B 2 535 ? 51.385 -12.757 15.648 1.00 20.00 ? 535 LYS A HZ2    1 
ATOM   6935 H HZ3    . LYS B 2 535 ? 49.911 -12.604 14.821 1.00 20.00 ? 535 LYS A HZ3    1 
ATOM   6936 N N      . PRO B 2 536 ? 49.021 -9.270  9.167  1.00 28.21 ? 536 PRO A N      1 
ATOM   6937 C CA     . PRO B 2 536 ? 48.307 -8.006  9.045  1.00 27.18 ? 536 PRO A CA     1 
ATOM   6938 C C      . PRO B 2 536 ? 48.253 -7.439  10.444 1.00 25.44 ? 536 PRO A C      1 
ATOM   6939 O O      . PRO B 2 536 ? 48.542 -8.160  11.407 1.00 24.47 ? 536 PRO A O      1 
ATOM   6940 C CB     . PRO B 2 536 ? 46.919 -8.449  8.627  1.00 26.40 ? 536 PRO A CB     1 
ATOM   6941 C CG     . PRO B 2 536 ? 47.207 -9.634  7.812  1.00 27.86 ? 536 PRO A CG     1 
ATOM   6942 C CD     . PRO B 2 536 ? 48.181 -10.364 8.680  1.00 26.55 ? 536 PRO A CD     1 
ATOM   6943 N N      . VAL B 2 537 ? 47.890 -6.162  10.561 1.00 21.23 ? 537 VAL A N      1 
ATOM   6944 C CA     . VAL B 2 537 ? 47.795 -5.492  11.858 1.00 18.05 ? 537 VAL A CA     1 
ATOM   6945 C C      . VAL B 2 537 ? 46.478 -4.727  11.904 1.00 18.19 ? 537 VAL A C      1 
ATOM   6946 O O      . VAL B 2 537 ? 46.183 -3.939  11.011 1.00 19.70 ? 537 VAL A O      1 
ATOM   6947 C CB     . VAL B 2 537 ? 48.972 -4.507  12.090 1.00 15.88 ? 537 VAL A CB     1 
ATOM   6948 C CG1    . VAL B 2 537 ? 48.931 -4.007  13.525 1.00 14.63 ? 537 VAL A CG1    1 
ATOM   6949 C CG2    . VAL B 2 537 ? 50.325 -5.185  11.806 1.00 13.47 ? 537 VAL A CG2    1 
ATOM   6950 H H      . VAL B 2 537 ? 47.674 -5.654  9.755  1.00 20.00 ? 537 VAL A H      1 
ATOM   6951 N N      . PHE B 2 538 ? 45.667 -4.996  12.913 1.00 16.66 ? 538 PHE A N      1 
ATOM   6952 C CA     . PHE B 2 538 ? 44.381 -4.339  13.018 1.00 17.53 ? 538 PHE A CA     1 
ATOM   6953 C C      . PHE B 2 538 ? 44.245 -3.397  14.220 1.00 15.11 ? 538 PHE A C      1 
ATOM   6954 O O      . PHE B 2 538 ? 44.361 -3.832  15.365 1.00 14.61 ? 538 PHE A O      1 
ATOM   6955 C CB     . PHE B 2 538 ? 43.275 -5.396  13.051 1.00 20.15 ? 538 PHE A CB     1 
ATOM   6956 C CG     . PHE B 2 538 ? 42.951 -5.980  11.701 1.00 21.98 ? 538 PHE A CG     1 
ATOM   6957 C CD1    . PHE B 2 538 ? 43.744 -6.974  11.146 1.00 20.27 ? 538 PHE A CD1    1 
ATOM   6958 C CD2    . PHE B 2 538 ? 41.835 -5.555  10.994 1.00 20.01 ? 538 PHE A CD2    1 
ATOM   6959 C CE1    . PHE B 2 538 ? 43.422 -7.536  9.906  1.00 18.03 ? 538 PHE A CE1    1 
ATOM   6960 C CE2    . PHE B 2 538 ? 41.511 -6.106  9.760  1.00 18.09 ? 538 PHE A CE2    1 
ATOM   6961 C CZ     . PHE B 2 538 ? 42.307 -7.100  9.219  1.00 17.64 ? 538 PHE A CZ     1 
ATOM   6962 H H      . PHE B 2 538 ? 45.940 -5.658  13.582 1.00 20.00 ? 538 PHE A H      1 
ATOM   6963 N N      . ASN B 2 539 ? 44.016 -2.108  13.965 1.00 13.73 ? 539 ASN A N      1 
ATOM   6964 C CA     . ASN B 2 539 ? 43.850 -1.139  15.042 1.00 13.34 ? 539 ASN A CA     1 
ATOM   6965 C C      . ASN B 2 539 ? 42.411 -1.146  15.448 1.00 14.89 ? 539 ASN A C      1 
ATOM   6966 O O      . ASN B 2 539 ? 41.526 -1.168  14.592 1.00 16.37 ? 539 ASN A O      1 
ATOM   6967 C CB     . ASN B 2 539 ? 44.162 0.267   14.589 1.00 12.23 ? 539 ASN A CB     1 
ATOM   6968 C CG     . ASN B 2 539 ? 45.593 0.443   14.162 1.00 11.52 ? 539 ASN A CG     1 
ATOM   6969 O OD1    . ASN B 2 539 ? 46.540 0.085   14.878 1.00 12.04 ? 539 ASN A OD1    1 
ATOM   6970 N ND2    . ASN B 2 539 ? 45.766 1.041   12.977 1.00 11.00 ? 539 ASN A ND2    1 
ATOM   6971 H H      . ASN B 2 539 ? 43.948 -1.801  13.040 1.00 20.00 ? 539 ASN A H      1 
ATOM   6972 H HD21   . ASN B 2 539 ? 46.608 1.198   12.642 1.00 20.00 ? 539 ASN A HD21   1 
ATOM   6973 H HD22   . ASN B 2 539 ? 44.928 1.341   12.467 1.00 20.00 ? 539 ASN A HD22   1 
ATOM   6974 N N      . ARG B 2 540 ? 42.161 -1.133  16.750 1.00 16.28 ? 540 ARG A N      1 
ATOM   6975 C CA     . ARG B 2 540 ? 40.784 -1.116  17.210 1.00 18.42 ? 540 ARG A CA     1 
ATOM   6976 C C      . ARG B 2 540 ? 40.416 0.322   17.252 1.00 17.83 ? 540 ARG A C      1 
ATOM   6977 O O      . ARG B 2 540 ? 40.969 1.081   18.055 1.00 18.35 ? 540 ARG A O      1 
ATOM   6978 C CB     . ARG B 2 540 ? 40.623 -1.686  18.609 1.00 19.27 ? 540 ARG A CB     1 
ATOM   6979 C CG     . ARG B 2 540 ? 39.199 -1.494  19.089 1.00 23.17 ? 540 ARG A CG     1 
ATOM   6980 C CD     . ARG B 2 540 ? 38.950 -2.137  20.413 1.00 26.55 ? 540 ARG A CD     1 
ATOM   6981 N NE     . ARG B 2 540 ? 39.742 -1.530  21.482 1.00 29.78 ? 540 ARG A NE     1 
ATOM   6982 C CZ     . ARG B 2 540 ? 39.499 -1.753  22.767 1.00 31.46 ? 540 ARG A CZ     1 
ATOM   6983 N NH1    . ARG B 2 540 ? 38.488 -2.548  23.096 1.00 31.90 ? 540 ARG A NH1    1 
ATOM   6984 N NH2    . ARG B 2 540 ? 40.239 -1.190  23.710 1.00 32.41 ? 540 ARG A NH2    1 
ATOM   6985 H H      . ARG B 2 540 ? 42.911 -1.157  17.392 1.00 20.00 ? 540 ARG A H      1 
ATOM   6986 H HE     . ARG B 2 540 ? 40.455 -0.900  21.263 1.00 20.00 ? 540 ARG A HE     1 
ATOM   6987 H HH11   . ARG B 2 540 ? 37.946 -3.008  22.374 1.00 20.00 ? 540 ARG A HH11   1 
ATOM   6988 H HH12   . ARG B 2 540 ? 38.296 -2.778  24.049 1.00 20.00 ? 540 ARG A HH12   1 
ATOM   6989 H HH21   . ARG B 2 540 ? 40.947 -0.554  23.481 1.00 20.00 ? 540 ARG A HH21   1 
ATOM   6990 H HH22   . ARG B 2 540 ? 40.005 -1.381  24.680 1.00 20.00 ? 540 ARG A HH22   1 
ATOM   6991 N N      . THR B 2 541 ? 39.480 0.686   16.384 1.00 13.12 ? 541 THR A N      1 
ATOM   6992 C CA     . THR B 2 541 ? 38.993 2.051   16.271 1.00 11.04 ? 541 THR A CA     1 
ATOM   6993 C C      . THR B 2 541 ? 38.228 2.447   17.526 1.00 11.18 ? 541 THR A C      1 
ATOM   6994 O O      . THR B 2 541 ? 38.559 3.427   18.192 1.00 11.73 ? 541 THR A O      1 
ATOM   6995 C CB     . THR B 2 541 ? 38.071 2.187   15.038 1.00 7.74  ? 541 THR A CB     1 
ATOM   6996 O OG1    . THR B 2 541 ? 38.848 2.033   13.849 1.00 4.04  ? 541 THR A OG1    1 
ATOM   6997 C CG2    . THR B 2 541 ? 37.355 3.517   15.032 1.00 4.97  ? 541 THR A CG2    1 
ATOM   6998 H H      . THR B 2 541 ? 39.114 0.013   15.779 1.00 20.00 ? 541 THR A H      1 
ATOM   6999 H HG1    . THR B 2 541 ? 38.303 2.122   13.081 1.00 20.00 ? 541 THR A HG1    1 
ATOM   7000 N N      . VAL B 2 542 ? 37.179 1.694   17.811 1.00 12.67 ? 542 VAL A N      1 
ATOM   7001 C CA     . VAL B 2 542 ? 36.333 1.937   18.972 1.00 13.22 ? 542 VAL A CA     1 
ATOM   7002 C C      . VAL B 2 542 ? 35.627 0.637   19.371 1.00 14.26 ? 542 VAL A C      1 
ATOM   7003 O O      . VAL B 2 542 ? 35.334 -0.207  18.523 1.00 16.74 ? 542 VAL A O      1 
ATOM   7004 C CB     . VAL B 2 542 ? 35.281 3.017   18.665 1.00 12.41 ? 542 VAL A CB     1 
ATOM   7005 C CG1    . VAL B 2 542 ? 34.481 2.628   17.436 1.00 12.36 ? 542 VAL A CG1    1 
ATOM   7006 C CG2    . VAL B 2 542 ? 34.368 3.225   19.837 1.00 10.57 ? 542 VAL A CG2    1 
ATOM   7007 H H      . VAL B 2 542 ? 37.006 0.906   17.243 1.00 20.00 ? 542 VAL A H      1 
ATOM   7008 N N      . GLY B 2 543 ? 35.403 0.445   20.663 1.00 17.98 ? 543 GLY A N      1 
ATOM   7009 C CA     . GLY B 2 543 ? 34.735 -0.762  21.096 1.00 19.17 ? 543 GLY A CA     1 
ATOM   7010 C C      . GLY B 2 543 ? 33.251 -0.632  20.867 1.00 22.50 ? 543 GLY A C      1 
ATOM   7011 O O      . GLY B 2 543 ? 32.773 0.425   20.464 1.00 21.07 ? 543 GLY A O      1 
ATOM   7012 H H      . GLY B 2 543 ? 35.679 1.124   21.295 1.00 20.00 ? 543 GLY A H      1 
ATOM   7013 N N      . LEU B 2 544 ? 32.529 -1.719  21.098 1.00 24.94 ? 544 LEU A N      1 
ATOM   7014 C CA     . LEU B 2 544 ? 31.083 -1.746  20.951 1.00 26.97 ? 544 LEU A CA     1 
ATOM   7015 C C      . LEU B 2 544 ? 30.464 -1.394  22.300 1.00 28.87 ? 544 LEU A C      1 
ATOM   7016 O O      . LEU B 2 544 ? 31.133 -1.496  23.339 1.00 26.49 ? 544 LEU A O      1 
ATOM   7017 C CB     . LEU B 2 544 ? 30.632 -3.152  20.571 1.00 27.45 ? 544 LEU A CB     1 
ATOM   7018 C CG     . LEU B 2 544 ? 30.281 -3.523  19.136 1.00 26.01 ? 544 LEU A CG     1 
ATOM   7019 C CD1    . LEU B 2 544 ? 31.277 -2.948  18.155 1.00 27.71 ? 544 LEU A CD1    1 
ATOM   7020 C CD2    . LEU B 2 544 ? 30.282 -5.008  19.038 1.00 26.19 ? 544 LEU A CD2    1 
ATOM   7021 H H      . LEU B 2 544 ? 32.977 -2.519  21.422 1.00 20.00 ? 544 LEU A H      1 
ATOM   7022 N N      . ARG B 2 545 ? 29.191 -0.996  22.282 1.00 33.98 ? 545 ARG A N      1 
ATOM   7023 C CA     . ARG B 2 545 ? 28.480 -0.669  23.513 1.00 39.09 ? 545 ARG A CA     1 
ATOM   7024 C C      . ARG B 2 545 ? 28.429 -1.929  24.398 1.00 41.75 ? 545 ARG A C      1 
ATOM   7025 O O      . ARG B 2 545 ? 27.667 -2.856  24.133 1.00 40.62 ? 545 ARG A O      1 
ATOM   7026 C CB     . ARG B 2 545 ? 27.067 -0.194  23.187 1.00 41.37 ? 545 ARG A CB     1 
ATOM   7027 C CG     . ARG B 2 545 ? 26.244 0.196   24.391 1.00 45.35 ? 545 ARG A CG     1 
ATOM   7028 C CD     . ARG B 2 545 ? 24.870 0.639   23.946 1.00 49.34 ? 545 ARG A CD     1 
ATOM   7029 N NE     . ARG B 2 545 ? 24.111 1.289   25.008 1.00 50.79 ? 545 ARG A NE     1 
ATOM   7030 C CZ     . ARG B 2 545 ? 24.483 2.410   25.628 1.00 54.39 ? 545 ARG A CZ     1 
ATOM   7031 N NH1    . ARG B 2 545 ? 25.631 3.016   25.324 1.00 54.80 ? 545 ARG A NH1    1 
ATOM   7032 N NH2    . ARG B 2 545 ? 23.712 2.921   26.574 1.00 55.59 ? 545 ARG A NH2    1 
ATOM   7033 H H      . ARG B 2 545 ? 28.704 -0.962  21.433 1.00 20.00 ? 545 ARG A H      1 
ATOM   7034 H HE     . ARG B 2 545 ? 23.266 0.880   25.289 1.00 20.00 ? 545 ARG A HE     1 
ATOM   7035 H HH11   . ARG B 2 545 ? 26.243 2.625   24.634 1.00 20.00 ? 545 ARG A HH11   1 
ATOM   7036 H HH12   . ARG B 2 545 ? 25.901 3.854   25.801 1.00 20.00 ? 545 ARG A HH12   1 
ATOM   7037 H HH21   . ARG B 2 545 ? 22.856 2.475   26.813 1.00 20.00 ? 545 ARG A HH21   1 
ATOM   7038 H HH22   . ARG B 2 545 ? 23.974 3.761   27.023 1.00 20.00 ? 545 ARG A HH22   1 
ATOM   7039 N N      . ASP B 2 546 ? 29.287 -1.976  25.411 1.00 45.48 ? 546 ASP A N      1 
ATOM   7040 C CA     . ASP B 2 546 ? 29.342 -3.113  26.322 1.00 48.06 ? 546 ASP A CA     1 
ATOM   7041 C C      . ASP B 2 546 ? 28.422 -2.823  27.498 1.00 47.61 ? 546 ASP A C      1 
ATOM   7042 O O      . ASP B 2 546 ? 28.581 -1.802  28.165 1.00 47.29 ? 546 ASP A O      1 
ATOM   7043 C CB     . ASP B 2 546 ? 30.776 -3.296  26.824 1.00 51.12 ? 546 ASP A CB     1 
ATOM   7044 C CG     . ASP B 2 546 ? 31.155 -4.751  26.993 1.00 55.00 ? 546 ASP A CG     1 
ATOM   7045 O OD1    . ASP B 2 546 ? 30.262 -5.568  27.310 1.00 56.64 ? 546 ASP A OD1    1 
ATOM   7046 O OD2    . ASP B 2 546 ? 32.350 -5.080  26.801 1.00 55.23 ? 546 ASP A OD2    1 
ATOM   7047 H H      . ASP B 2 546 ? 29.892 -1.224  25.557 1.00 20.00 ? 546 ASP A H      1 
ATOM   7048 N N      . THR B 2 547 ? 27.478 -3.713  27.780 1.00 47.68 ? 547 THR A N      1 
ATOM   7049 C CA     . THR B 2 547 ? 26.554 -3.476  28.892 1.00 48.75 ? 547 THR A CA     1 
ATOM   7050 C C      . THR B 2 547 ? 25.908 -4.736  29.479 1.00 49.66 ? 547 THR A C      1 
ATOM   7051 O O      . THR B 2 547 ? 26.584 -5.650  29.957 1.00 48.31 ? 547 THR A O      1 
ATOM   7052 C CB     . THR B 2 547 ? 25.412 -2.511  28.475 1.00 48.99 ? 547 THR A CB     1 
ATOM   7053 O OG1    . THR B 2 547 ? 25.013 -2.792  27.122 1.00 49.09 ? 547 THR A OG1    1 
ATOM   7054 C CG2    . THR B 2 547 ? 25.838 -1.056  28.592 1.00 49.72 ? 547 THR A CG2    1 
ATOM   7055 H H      . THR B 2 547 ? 27.400 -4.530  27.253 1.00 20.00 ? 547 THR A H      1 
ATOM   7056 H HG1    . THR B 2 547 ? 24.303 -2.210  26.851 1.00 20.00 ? 547 THR A HG1    1 
HETATM 7057 P PG     . ATP C 3 .   ? 49.339 25.923  19.133 1.00 52.23 ? 999 ATP A PG     1 
HETATM 7058 O O1G    . ATP C 3 .   ? 50.171 26.285  20.359 1.00 52.80 ? 999 ATP A O1G    1 
HETATM 7059 O O2G    . ATP C 3 .   ? 48.560 24.621  19.325 1.00 53.77 ? 999 ATP A O2G    1 
HETATM 7060 O O3G    . ATP C 3 .   ? 50.153 25.949  17.845 1.00 55.30 ? 999 ATP A O3G    1 
HETATM 7061 P PB     . ATP C 3 .   ? 46.961 27.091  17.961 1.00 37.27 ? 999 ATP A PB     1 
HETATM 7062 O O1B    . ATP C 3 .   ? 46.661 25.676  17.611 1.00 38.04 ? 999 ATP A O1B    1 
HETATM 7063 O O2B    . ATP C 3 .   ? 45.937 27.901  18.666 1.00 39.63 ? 999 ATP A O2B    1 
HETATM 7064 O O3B    . ATP C 3 .   ? 48.242 27.070  18.907 1.00 46.37 ? 999 ATP A O3B    1 
HETATM 7065 P PA     . ATP C 3 .   ? 47.053 27.616  15.070 1.00 16.86 ? 999 ATP A PA     1 
HETATM 7066 O O1A    . ATP C 3 .   ? 47.450 28.822  14.333 1.00 19.51 ? 999 ATP A O1A    1 
HETATM 7067 O O2A    . ATP C 3 .   ? 47.573 26.292  14.645 1.00 21.66 ? 999 ATP A O2A    1 
HETATM 7068 O O3A    . ATP C 3 .   ? 47.423 27.863  16.626 1.00 28.42 ? 999 ATP A O3A    1 
HETATM 7069 O "O5'"  . ATP C 3 .   ? 45.463 27.518  15.020 1.00 13.89 ? 999 ATP A "O5'"  1 
HETATM 7070 C "C5'"  . ATP C 3 .   ? 44.765 27.807  13.808 1.00 8.98  ? 999 ATP A "C5'"  1 
HETATM 7071 C "C4'"  . ATP C 3 .   ? 43.310 28.127  14.127 1.00 4.11  ? 999 ATP A "C4'"  1 
HETATM 7072 O "O4'"  . ATP C 3 .   ? 42.797 26.963  14.818 1.00 5.11  ? 999 ATP A "O4'"  1 
HETATM 7073 C "C3'"  . ATP C 3 .   ? 43.231 29.270  15.138 1.00 7.81  ? 999 ATP A "C3'"  1 
HETATM 7074 O "O3'"  . ATP C 3 .   ? 42.853 30.537  14.512 1.00 8.76  ? 999 ATP A "O3'"  1 
HETATM 7075 C "C2'"  . ATP C 3 .   ? 42.199 28.843  16.190 1.00 5.94  ? 999 ATP A "C2'"  1 
HETATM 7076 O "O2'"  . ATP C 3 .   ? 41.012 29.553  16.186 1.00 6.69  ? 999 ATP A "O2'"  1 
HETATM 7077 C "C1'"  . ATP C 3 .   ? 41.944 27.381  15.844 1.00 4.50  ? 999 ATP A "C1'"  1 
HETATM 7078 N N9     . ATP C 3 .   ? 42.101 26.480  16.955 1.00 2.00  ? 999 ATP A N9     1 
HETATM 7079 C C8     . ATP C 3 .   ? 43.270 26.082  17.527 1.00 2.00  ? 999 ATP A C8     1 
HETATM 7080 N N7     . ATP C 3 .   ? 43.105 25.273  18.538 1.00 2.00  ? 999 ATP A N7     1 
HETATM 7081 C C5     . ATP C 3 .   ? 41.727 25.122  18.618 1.00 2.00  ? 999 ATP A C5     1 
HETATM 7082 C C6     . ATP C 3 .   ? 40.911 24.400  19.488 1.00 2.31  ? 999 ATP A C6     1 
HETATM 7083 N N6     . ATP C 3 .   ? 41.392 23.628  20.468 1.00 2.58  ? 999 ATP A N6     1 
HETATM 7084 N N1     . ATP C 3 .   ? 39.577 24.480  19.314 1.00 2.00  ? 999 ATP A N1     1 
HETATM 7085 C C2     . ATP C 3 .   ? 39.111 25.228  18.316 1.00 2.09  ? 999 ATP A C2     1 
HETATM 7086 N N3     . ATP C 3 .   ? 39.780 25.945  17.417 1.00 2.36  ? 999 ATP A N3     1 
HETATM 7087 C C4     . ATP C 3 .   ? 41.099 25.854  17.638 1.00 2.01  ? 999 ATP A C4     1 
HETATM 7088 H "HO2'" . ATP C 3 .   ? 40.483 29.246  16.928 1.00 20.00 ? 999 ATP A "HO2'" 1 
HETATM 7089 H HN61   . ATP C 3 .   ? 42.388 23.551  20.613 1.00 20.00 ? 999 ATP A HN61   1 
HETATM 7090 H HN62   . ATP C 3 .   ? 40.760 23.123  21.074 1.00 20.00 ? 999 ATP A HN62   1 
HETATM 7091 O O      . HOH D 4 .   ? 44.298 42.912  28.911 1.00 2.01  ? 714 HOH B O      1 
HETATM 7092 O O      . HOH E 4 .   ? 39.090 36.223  26.554 1.00 6.23  ? 701 HOH A O      1 
HETATM 7093 O O      . HOH E 4 .   ? 32.825 22.781  21.910 1.00 2.01  ? 702 HOH A O      1 
HETATM 7094 O O      . HOH E 4 .   ? 28.591 26.483  12.071 1.00 14.00 ? 703 HOH A O      1 
HETATM 7095 O O      . HOH E 4 .   ? 28.076 9.545   12.848 1.00 8.04  ? 704 HOH A O      1 
HETATM 7096 O O      . HOH E 4 .   ? 55.563 32.173  0.419  1.00 19.63 ? 705 HOH A O      1 
HETATM 7097 O O      . HOH E 4 .   ? 58.331 57.788  13.909 1.00 2.01  ? 706 HOH A O      1 
HETATM 7098 O O      . HOH E 4 .   ? 56.487 59.012  24.357 1.00 2.00  ? 707 HOH A O      1 
HETATM 7099 O O      . HOH E 4 .   ? 51.866 41.121  18.025 1.00 30.34 ? 708 HOH A O      1 
HETATM 7100 O O      . HOH E 4 .   ? 43.422 34.405  14.380 1.00 13.16 ? 709 HOH A O      1 
HETATM 7101 O O      . HOH E 4 .   ? 39.352 29.537  13.495 1.00 2.01  ? 710 HOH A O      1 
HETATM 7102 O O      . HOH E 4 .   ? 47.698 35.712  8.579  1.00 2.01  ? 711 HOH A O      1 
HETATM 7103 O O      . HOH E 4 .   ? 33.733 -9.490  5.011  1.00 2.92  ? 712 HOH A O      1 
HETATM 7104 O O      . HOH E 4 .   ? 34.179 -16.883 21.244 1.00 2.72  ? 713 HOH A O      1 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   U   1   1   ?   ?   ?   B . n 
A 1 2   G   2   2   2   G   G   B . n 
A 1 3   G   3   3   3   G   G   B . n 
A 1 4   G   4   4   4   G   G   B . n 
A 1 5   G   5   5   5   G   G   B . n 
A 1 6   U   6   6   6   U   U   B . n 
A 1 7   A   7   7   7   A   A   B . n 
A 1 8   U   8   8   8   U   U   B . n 
A 1 9   C   9   9   9   C   C   B . n 
A 1 10  G   10  10  10  G   G   B . n 
A 1 11  C   11  11  11  C   C   B . n 
A 1 12  C   12  12  12  C   C   B . n 
A 1 13  A   13  13  13  A   A   B . n 
A 1 14  A   14  14  14  A   A   B . n 
A 1 15  G   15  15  15  G   G   B . n 
A 1 16  C   16  16  16  C   C   B . n 
A 1 17  G   17  18  18  G   G   B . n 
A 1 18  G   18  19  19  G   G   B . n 
A 1 19  U   19  20  20  U   U   B . n 
A 1 20  A   20  21  21  A   A   B . n 
A 1 21  A   21  22  22  A   A   B . n 
A 1 22  G   22  23  23  G   G   B . n 
A 1 23  G   23  24  24  G   G   B . n 
A 1 24  C   24  25  25  C   C   B . n 
A 1 25  A   25  26  26  A   A   B . n 
A 1 26  C   26  27  27  C   C   B . n 
A 1 27  C   27  28  28  C   C   B . n 
A 1 28  G   28  29  29  G   G   B . n 
A 1 29  G   29  30  30  G   G   B . n 
A 1 30  A   30  31  31  A   A   B . n 
A 1 31  U   31  32  32  U   U   B . n 
A 1 32  U   32  33  33  U   U   B . n 
A 1 33  C   33  34  34  C   C   B . n 
A 1 34  U   34  35  35  U   U   B . n 
A 1 35  G   35  36  36  G   G   B . n 
A 1 36  A   36  37  37  A   A   B . n 
A 1 37  U   37  38  38  U   U   B . n 
A 1 38  U   38  39  39  U   U   B . n 
A 1 39  C   39  40  40  C   C   B . n 
A 1 40  C   40  41  41  C   C   B . n 
A 1 41  G   41  42  42  G   G   B . n 
A 1 42  G   42  43  43  G   G   B . n 
A 1 43  C   43  44  44  C   C   B . n 
A 1 44  A   44  45  45  A   A   B . n 
A 1 45  U   45  46  46  U   U   B . n 
A 1 46  U   46  47  47  U   U   B . n 
A 1 47  C   47  48  48  C   C   B . n 
A 1 48  C   48  49  49  C   C   B . n 
A 1 49  G   49  50  50  G   G   B . n 
A 1 50  A   50  51  51  A   A   B . n 
A 1 51  G   51  52  52  G   G   B . n 
A 1 52  G   52  53  53  G   G   B . n 
A 1 53  U   53  54  54  U   U   B . n 
A 1 54  U   54  55  55  U   U   B . n 
A 1 55  C   55  56  56  C   C   B . n 
A 1 56  G   56  57  57  G   G   B . n 
A 1 57  A   57  58  58  A   A   B . n 
A 1 58  A   58  59  59  A   A   B . n 
A 1 59  U   59  60  60  U   U   B . n 
A 1 60  C   60  61  61  C   C   B . n 
A 1 61  C   61  62  62  C   C   B . n 
A 1 62  U   62  63  63  U   U   B . n 
A 1 63  C   63  64  64  C   C   B . n 
A 1 64  G   64  65  65  G   G   B . n 
A 1 65  U   65  66  66  U   U   B . n 
A 1 66  A   66  67  67  A   A   B . n 
A 1 67  C   67  68  68  C   C   B . n 
A 1 68  C   68  69  69  C   C   B . n 
A 1 69  C   69  70  70  C   C   B . n 
A 1 70  C   70  71  71  C   C   B . n 
A 1 71  A   71  72  72  A   A   B . n 
A 1 72  G   72  73  73  G   G   B . n 
A 1 73  C   73  74  74  C   C   B . n 
A 1 74  C   74  75  75  C   C   B . n 
A 1 75  A   75  76  76  A   A   B . n 
B 2 1   SER 1   1   ?   ?   ?   A . n 
B 2 2   GLU 2   2   ?   ?   ?   A . n 
B 2 3   ALA 3   3   ?   ?   ?   A . n 
B 2 4   GLU 4   4   ?   ?   ?   A . n 
B 2 5   ALA 5   5   ?   ?   ?   A . n 
B 2 6   ARG 6   6   ?   ?   ?   A . n 
B 2 7   PRO 7   7   ?   ?   ?   A . n 
B 2 8   THR 8   8   8   THR THR A . n 
B 2 9   ASN 9   9   9   ASN ASN A . n 
B 2 10  PHE 10  10  10  PHE PHE A . n 
B 2 11  ILE 11  11  11  ILE ILE A . n 
B 2 12  ARG 12  12  12  ARG ARG A . n 
B 2 13  GLN 13  13  13  GLN GLN A . n 
B 2 14  ILE 14  14  14  ILE ILE A . n 
B 2 15  ILE 15  15  15  ILE ILE A . n 
B 2 16  ASP 16  16  16  ASP ASP A . n 
B 2 17  GLU 17  17  17  GLU GLU A . n 
B 2 18  ASP 18  18  18  ASP ASP A . n 
B 2 19  LEU 19  19  19  LEU LEU A . n 
B 2 20  ALA 20  20  20  ALA ALA A . n 
B 2 21  SER 21  21  21  SER SER A . n 
B 2 22  GLY 22  22  22  GLY GLY A . n 
B 2 23  LYS 23  23  23  LYS LYS A . n 
B 2 24  HIS 24  24  24  HIS HIS A . n 
B 2 25  THR 25  25  25  THR THR A . n 
B 2 26  THR 26  26  26  THR THR A . n 
B 2 27  VAL 27  27  27  VAL VAL A . n 
B 2 28  HIS 28  28  28  HIS HIS A . n 
B 2 29  THR 29  29  29  THR THR A . n 
B 2 30  ARG 30  30  30  ARG ARG A . n 
B 2 31  PHE 31  31  31  PHE PHE A . n 
B 2 32  PRO 32  32  32  PRO PRO A . n 
B 2 33  PRO 33  33  33  PRO PRO A . n 
B 2 34  GLU 34  34  34  GLU GLU A . n 
B 2 35  PRO 35  35  35  PRO PRO A . n 
B 2 36  ASN 36  36  36  ASN ASN A . n 
B 2 37  GLY 37  37  37  GLY GLY A . n 
B 2 38  TYR 38  38  38  TYR TYR A . n 
B 2 39  LEU 39  39  39  LEU LEU A . n 
B 2 40  HIS 40  40  40  HIS HIS A . n 
B 2 41  ILE 41  41  41  ILE ILE A . n 
B 2 42  GLY 42  42  42  GLY GLY A . n 
B 2 43  HIS 43  43  43  HIS HIS A . n 
B 2 44  ALA 44  44  44  ALA ALA A . n 
B 2 45  LYS 45  45  45  LYS LYS A . n 
B 2 46  SER 46  46  46  SER SER A . n 
B 2 47  ILE 47  47  47  ILE ILE A . n 
B 2 48  CYS 48  48  48  CYS CYS A . n 
B 2 49  LEU 49  49  49  LEU LEU A . n 
B 2 50  ASN 50  50  50  ASN ASN A . n 
B 2 51  PHE 51  51  51  PHE PHE A . n 
B 2 52  GLY 52  52  52  GLY GLY A . n 
B 2 53  ILE 53  53  53  ILE ILE A . n 
B 2 54  ALA 54  54  54  ALA ALA A . n 
B 2 55  GLN 55  55  55  GLN GLN A . n 
B 2 56  ASP 56  56  56  ASP ASP A . n 
B 2 57  TYR 57  57  57  TYR TYR A . n 
B 2 58  LYS 58  58  58  LYS LYS A . n 
B 2 59  GLY 59  59  59  GLY GLY A . n 
B 2 60  GLN 60  60  60  GLN GLN A . n 
B 2 61  CYS 61  61  61  CYS CYS A . n 
B 2 62  ASN 62  62  62  ASN ASN A . n 
B 2 63  LEU 63  63  63  LEU LEU A . n 
B 2 64  ARG 64  64  64  ARG ARG A . n 
B 2 65  PHE 65  65  65  PHE PHE A . n 
B 2 66  ASP 66  66  66  ASP ASP A . n 
B 2 67  ASP 67  67  67  ASP ASP A . n 
B 2 68  THR 68  68  68  THR THR A . n 
B 2 69  ASN 69  69  69  ASN ASN A . n 
B 2 70  PRO 70  70  70  PRO PRO A . n 
B 2 71  VAL 71  71  71  VAL VAL A . n 
B 2 72  LYS 72  72  72  LYS LYS A . n 
B 2 73  GLU 73  73  73  GLU GLU A . n 
B 2 74  ASP 74  74  74  ASP ASP A . n 
B 2 75  ILE 75  75  75  ILE ILE A . n 
B 2 76  GLU 76  76  76  GLU GLU A . n 
B 2 77  TYR 77  77  77  TYR TYR A . n 
B 2 78  VAL 78  78  78  VAL VAL A . n 
B 2 79  GLU 79  79  79  GLU GLU A . n 
B 2 80  SER 80  80  80  SER SER A . n 
B 2 81  ILE 81  81  81  ILE ILE A . n 
B 2 82  LYS 82  82  82  LYS LYS A . n 
B 2 83  ASN 83  83  83  ASN ASN A . n 
B 2 84  ASP 84  84  84  ASP ASP A . n 
B 2 85  VAL 85  85  85  VAL VAL A . n 
B 2 86  GLU 86  86  86  GLU GLU A . n 
B 2 87  TRP 87  87  87  TRP TRP A . n 
B 2 88  LEU 88  88  88  LEU LEU A . n 
B 2 89  GLY 89  89  89  GLY GLY A . n 
B 2 90  PHE 90  90  90  PHE PHE A . n 
B 2 91  HIS 91  91  91  HIS HIS A . n 
B 2 92  TRP 92  92  92  TRP TRP A . n 
B 2 93  SER 93  93  93  SER SER A . n 
B 2 94  GLY 94  94  94  GLY GLY A . n 
B 2 95  ASN 95  95  95  ASN ASN A . n 
B 2 96  VAL 96  96  96  VAL VAL A . n 
B 2 97  ARG 97  97  97  ARG ARG A . n 
B 2 98  TYR 98  98  98  TYR TYR A . n 
B 2 99  SER 99  99  99  SER SER A . n 
B 2 100 SER 100 100 100 SER SER A . n 
B 2 101 ASP 101 101 101 ASP ASP A . n 
B 2 102 TYR 102 102 102 TYR TYR A . n 
B 2 103 PHE 103 103 103 PHE PHE A . n 
B 2 104 ASP 104 104 104 ASP ASP A . n 
B 2 105 GLN 105 105 105 GLN GLN A . n 
B 2 106 LEU 106 106 106 LEU LEU A . n 
B 2 107 HIS 107 107 107 HIS HIS A . n 
B 2 108 ALA 108 108 108 ALA ALA A . n 
B 2 109 TYR 109 109 109 TYR TYR A . n 
B 2 110 ALA 110 110 110 ALA ALA A . n 
B 2 111 ILE 111 111 111 ILE ILE A . n 
B 2 112 GLU 112 112 112 GLU GLU A . n 
B 2 113 LEU 113 113 113 LEU LEU A . n 
B 2 114 ILE 114 114 114 ILE ILE A . n 
B 2 115 ASN 115 115 115 ASN ASN A . n 
B 2 116 LYS 116 116 116 LYS LYS A . n 
B 2 117 GLY 117 117 117 GLY GLY A . n 
B 2 118 LEU 118 118 118 LEU LEU A . n 
B 2 119 ALA 119 119 119 ALA ALA A . n 
B 2 120 TYR 120 120 120 TYR TYR A . n 
B 2 121 VAL 121 121 121 VAL VAL A . n 
B 2 122 ASP 122 122 122 ASP ASP A . n 
B 2 123 GLU 123 123 123 GLU GLU A . n 
B 2 124 LEU 124 124 124 LEU LEU A . n 
B 2 125 THR 125 125 125 THR THR A . n 
B 2 126 PRO 126 126 126 PRO PRO A . n 
B 2 127 GLU 127 127 127 GLU GLU A . n 
B 2 128 GLN 128 128 128 GLN GLN A . n 
B 2 129 THR 129 129 129 THR THR A . n 
B 2 130 ARG 130 130 130 ARG ARG A . n 
B 2 131 GLU 131 131 131 GLU GLU A . n 
B 2 132 TYR 132 132 132 TYR TYR A . n 
B 2 133 ARG 133 133 133 ARG ARG A . n 
B 2 134 GLY 134 134 134 GLY GLY A . n 
B 2 135 THR 135 135 135 THR THR A . n 
B 2 136 LEU 136 136 136 LEU LEU A . n 
B 2 137 THR 137 137 137 THR THR A . n 
B 2 138 GLN 138 138 138 GLN GLN A . n 
B 2 139 PRO 139 139 139 PRO PRO A . n 
B 2 140 GLY 140 140 140 GLY GLY A . n 
B 2 141 LYS 141 141 141 LYS LYS A . n 
B 2 142 ASN 142 142 142 ASN ASN A . n 
B 2 143 SER 143 143 143 SER SER A . n 
B 2 144 PRO 144 144 144 PRO PRO A . n 
B 2 145 TYR 145 145 145 TYR TYR A . n 
B 2 146 ARG 146 146 146 ARG ARG A . n 
B 2 147 ASP 147 147 147 ASP ASP A . n 
B 2 148 ARG 148 148 148 ARG ARG A . n 
B 2 149 SER 149 149 149 SER SER A . n 
B 2 150 VAL 150 150 150 VAL VAL A . n 
B 2 151 GLU 151 151 151 GLU GLU A . n 
B 2 152 GLU 152 152 152 GLU GLU A . n 
B 2 153 ASN 153 153 153 ASN ASN A . n 
B 2 154 LEU 154 154 154 LEU LEU A . n 
B 2 155 ALA 155 155 155 ALA ALA A . n 
B 2 156 LEU 156 156 156 LEU LEU A . n 
B 2 157 PHE 157 157 157 PHE PHE A . n 
B 2 158 GLU 158 158 158 GLU GLU A . n 
B 2 159 LYS 159 159 159 LYS LYS A . n 
B 2 160 MET 160 160 160 MET MET A . n 
B 2 161 ARG 161 161 161 ARG ARG A . n 
B 2 162 ALA 162 162 162 ALA ALA A . n 
B 2 163 GLY 163 163 163 GLY GLY A . n 
B 2 164 GLY 164 164 164 GLY GLY A . n 
B 2 165 PHE 165 165 165 PHE PHE A . n 
B 2 166 GLU 166 166 166 GLU GLU A . n 
B 2 167 GLU 167 167 167 GLU GLU A . n 
B 2 168 GLY 168 168 168 GLY GLY A . n 
B 2 169 LYS 169 169 169 LYS LYS A . n 
B 2 170 ALA 170 170 170 ALA ALA A . n 
B 2 171 CYS 171 171 171 CYS CYS A . n 
B 2 172 LEU 172 172 172 LEU LEU A . n 
B 2 173 ARG 173 173 173 ARG ARG A . n 
B 2 174 ALA 174 174 174 ALA ALA A . n 
B 2 175 LYS 175 175 175 LYS LYS A . n 
B 2 176 ILE 176 176 176 ILE ILE A . n 
B 2 177 ASP 177 177 177 ASP ASP A . n 
B 2 178 MET 178 178 178 MET MET A . n 
B 2 179 ALA 179 179 179 ALA ALA A . n 
B 2 180 SER 180 180 180 SER SER A . n 
B 2 181 PRO 181 181 181 PRO PRO A . n 
B 2 182 PHE 182 182 182 PHE PHE A . n 
B 2 183 ILE 183 183 183 ILE ILE A . n 
B 2 184 VAL 184 184 184 VAL VAL A . n 
B 2 185 MET 185 185 185 MET MET A . n 
B 2 186 ARG 186 186 186 ARG ARG A . n 
B 2 187 ASP 187 187 187 ASP ASP A . n 
B 2 188 PRO 188 188 188 PRO PRO A . n 
B 2 189 VAL 189 189 189 VAL VAL A . n 
B 2 190 LEU 190 190 190 LEU LEU A . n 
B 2 191 TYR 191 191 191 TYR TYR A . n 
B 2 192 ARG 192 192 192 ARG ARG A . n 
B 2 193 ILE 193 193 193 ILE ILE A . n 
B 2 194 LYS 194 194 194 LYS LYS A . n 
B 2 195 PHE 195 195 195 PHE PHE A . n 
B 2 196 ALA 196 196 196 ALA ALA A . n 
B 2 197 GLU 197 197 197 GLU GLU A . n 
B 2 198 HIS 198 198 198 HIS HIS A . n 
B 2 199 HIS 199 199 199 HIS HIS A . n 
B 2 200 GLN 200 200 200 GLN GLN A . n 
B 2 201 THR 201 201 201 THR THR A . n 
B 2 202 GLY 202 202 202 GLY GLY A . n 
B 2 203 ASN 203 203 203 ASN ASN A . n 
B 2 204 LYS 204 204 204 LYS LYS A . n 
B 2 205 TRP 205 205 205 TRP TRP A . n 
B 2 206 CYS 206 206 206 CYS CYS A . n 
B 2 207 ILE 207 207 207 ILE ILE A . n 
B 2 208 TYR 208 208 208 TYR TYR A . n 
B 2 209 PRO 209 209 209 PRO PRO A . n 
B 2 210 MET 210 210 210 MET MET A . n 
B 2 211 TYR 211 211 211 TYR TYR A . n 
B 2 212 ASP 212 212 212 ASP ASP A . n 
B 2 213 PHE 213 213 213 PHE PHE A . n 
B 2 214 THR 214 214 214 THR THR A . n 
B 2 215 HIS 215 215 215 HIS HIS A . n 
B 2 216 CYS 216 216 216 CYS CYS A . n 
B 2 217 ILE 217 217 217 ILE ILE A . n 
B 2 218 SER 218 218 218 SER SER A . n 
B 2 219 ASP 219 219 219 ASP ASP A . n 
B 2 220 ALA 220 220 220 ALA ALA A . n 
B 2 221 LEU 221 221 221 LEU LEU A . n 
B 2 222 GLU 222 222 222 GLU GLU A . n 
B 2 223 GLY 223 223 223 GLY GLY A . n 
B 2 224 ILE 224 224 224 ILE ILE A . n 
B 2 225 THR 225 225 225 THR THR A . n 
B 2 226 HIS 226 226 226 HIS HIS A . n 
B 2 227 SER 227 227 227 SER SER A . n 
B 2 228 LEU 228 228 228 LEU LEU A . n 
B 2 229 CYS 229 229 229 CYS CYS A . n 
B 2 230 THR 230 230 230 THR THR A . n 
B 2 231 LEU 231 231 231 LEU LEU A . n 
B 2 232 GLU 232 232 232 GLU GLU A . n 
B 2 233 PHE 233 233 233 PHE PHE A . n 
B 2 234 GLN 234 234 234 GLN GLN A . n 
B 2 235 ASP 235 235 235 ASP ASP A . n 
B 2 236 ASN 236 236 236 ASN ASN A . n 
B 2 237 ARG 237 237 237 ARG ARG A . n 
B 2 238 ARG 238 238 238 ARG ARG A . n 
B 2 239 LEU 239 239 239 LEU LEU A . n 
B 2 240 TYR 240 240 240 TYR TYR A . n 
B 2 241 ASP 241 241 241 ASP ASP A . n 
B 2 242 TRP 242 242 242 TRP TRP A . n 
B 2 243 VAL 243 243 243 VAL VAL A . n 
B 2 244 LEU 244 244 244 LEU LEU A . n 
B 2 245 ASP 245 245 245 ASP ASP A . n 
B 2 246 ASN 246 246 246 ASN ASN A . n 
B 2 247 ILE 247 247 247 ILE ILE A . n 
B 2 248 THR 248 248 248 THR THR A . n 
B 2 249 ILE 249 249 249 ILE ILE A . n 
B 2 250 PRO 250 250 250 PRO PRO A . n 
B 2 251 VAL 251 251 251 VAL VAL A . n 
B 2 252 HIS 252 252 252 HIS HIS A . n 
B 2 253 PRO 253 253 253 PRO PRO A . n 
B 2 254 ARG 254 254 254 ARG ARG A . n 
B 2 255 GLN 255 255 255 GLN GLN A . n 
B 2 256 TYR 256 256 256 TYR TYR A . n 
B 2 257 GLU 257 257 257 GLU GLU A . n 
B 2 258 PHE 258 258 258 PHE PHE A . n 
B 2 259 SER 259 259 259 SER SER A . n 
B 2 260 ARG 260 260 260 ARG ARG A . n 
B 2 261 LEU 261 261 261 LEU LEU A . n 
B 2 262 ASN 262 262 262 ASN ASN A . n 
B 2 263 LEU 263 263 263 LEU LEU A . n 
B 2 264 GLU 264 264 264 GLU GLU A . n 
B 2 265 TYR 265 265 265 TYR TYR A . n 
B 2 266 THR 266 266 266 THR THR A . n 
B 2 267 VAL 267 267 267 VAL VAL A . n 
B 2 268 MET 268 268 268 MET MET A . n 
B 2 269 SER 269 269 269 SER SER A . n 
B 2 270 LYS 270 270 270 LYS LYS A . n 
B 2 271 ARG 271 271 271 ARG ARG A . n 
B 2 272 LYS 272 272 272 LYS LYS A . n 
B 2 273 LEU 273 273 273 LEU LEU A . n 
B 2 274 ASN 274 274 274 ASN ASN A . n 
B 2 275 LEU 275 275 275 LEU LEU A . n 
B 2 276 LEU 276 276 276 LEU LEU A . n 
B 2 277 VAL 277 277 277 VAL VAL A . n 
B 2 278 THR 278 278 278 THR THR A . n 
B 2 279 ASP 279 279 279 ASP ASP A . n 
B 2 280 LYS 280 280 280 LYS LYS A . n 
B 2 281 HIS 281 281 281 HIS HIS A . n 
B 2 282 VAL 282 282 282 VAL VAL A . n 
B 2 283 GLU 283 283 283 GLU GLU A . n 
B 2 284 GLY 284 284 284 GLY GLY A . n 
B 2 285 TRP 285 285 285 TRP TRP A . n 
B 2 286 ASP 286 286 286 ASP ASP A . n 
B 2 287 ASP 287 287 287 ASP ASP A . n 
B 2 288 PRO 288 288 288 PRO PRO A . n 
B 2 289 ARG 289 289 289 ARG ARG A . n 
B 2 290 MET 290 290 290 MET MET A . n 
B 2 291 PRO 291 291 291 PRO PRO A . n 
B 2 292 THR 292 292 292 THR THR A . n 
B 2 293 ILE 293 293 293 ILE ILE A . n 
B 2 294 SER 294 294 294 SER SER A . n 
B 2 295 GLY 295 295 295 GLY GLY A . n 
B 2 296 LEU 296 296 296 LEU LEU A . n 
B 2 297 ARG 297 297 297 ARG ARG A . n 
B 2 298 ARG 298 298 298 ARG ARG A . n 
B 2 299 ARG 299 299 299 ARG ARG A . n 
B 2 300 GLY 300 300 300 GLY GLY A . n 
B 2 301 TYR 301 301 301 TYR TYR A . n 
B 2 302 THR 302 302 302 THR THR A . n 
B 2 303 ALA 303 303 303 ALA ALA A . n 
B 2 304 ALA 304 304 304 ALA ALA A . n 
B 2 305 SER 305 305 305 SER SER A . n 
B 2 306 ILE 306 306 306 ILE ILE A . n 
B 2 307 ARG 307 307 307 ARG ARG A . n 
B 2 308 GLU 308 308 308 GLU GLU A . n 
B 2 309 PHE 309 309 309 PHE PHE A . n 
B 2 310 CYS 310 310 310 CYS CYS A . n 
B 2 311 LYS 311 311 311 LYS LYS A . n 
B 2 312 ARG 312 312 312 ARG ARG A . n 
B 2 313 ILE 313 313 313 ILE ILE A . n 
B 2 314 GLY 314 314 314 GLY GLY A . n 
B 2 315 VAL 315 315 315 VAL VAL A . n 
B 2 316 THR 316 316 316 THR THR A . n 
B 2 317 LYS 317 317 317 LYS LYS A . n 
B 2 318 GLN 318 318 318 GLN GLN A . n 
B 2 319 ASP 319 319 319 ASP ASP A . n 
B 2 320 ASN 320 320 320 ASN ASN A . n 
B 2 321 THR 321 321 321 THR THR A . n 
B 2 322 ILE 322 322 322 ILE ILE A . n 
B 2 323 GLU 323 323 323 GLU GLU A . n 
B 2 324 MET 324 324 324 MET MET A . n 
B 2 325 ALA 325 325 325 ALA ALA A . n 
B 2 326 SER 326 326 326 SER SER A . n 
B 2 327 LEU 327 327 327 LEU LEU A . n 
B 2 328 GLU 328 328 328 GLU GLU A . n 
B 2 329 SER 329 329 329 SER SER A . n 
B 2 330 CYS 330 330 330 CYS CYS A . n 
B 2 331 ILE 331 331 331 ILE ILE A . n 
B 2 332 ARG 332 332 332 ARG ARG A . n 
B 2 333 GLU 333 333 333 GLU GLU A . n 
B 2 334 ASP 334 334 334 ASP ASP A . n 
B 2 335 LEU 335 335 335 LEU LEU A . n 
B 2 336 ASN 336 336 336 ASN ASN A . n 
B 2 337 GLU 337 337 337 GLU GLU A . n 
B 2 338 ASN 338 338 338 ASN ASN A . n 
B 2 339 ALA 339 339 339 ALA ALA A . n 
B 2 340 PRO 340 340 340 PRO PRO A . n 
B 2 341 ARG 341 341 341 ARG ARG A . n 
B 2 342 ALA 342 342 342 ALA ALA A . n 
B 2 343 MET 343 343 343 MET MET A . n 
B 2 344 ALA 344 344 344 ALA ALA A . n 
B 2 345 VAL 345 345 345 VAL VAL A . n 
B 2 346 ILE 346 346 346 ILE ILE A . n 
B 2 347 ASP 347 347 347 ASP ASP A . n 
B 2 348 PRO 348 348 348 PRO PRO A . n 
B 2 349 VAL 349 349 349 VAL VAL A . n 
B 2 350 LYS 350 350 350 LYS LYS A . n 
B 2 351 LEU 351 351 351 LEU LEU A . n 
B 2 352 VAL 352 352 352 VAL VAL A . n 
B 2 353 ILE 353 353 353 ILE ILE A . n 
B 2 354 GLU 354 354 354 GLU GLU A . n 
B 2 355 ASN 355 355 355 ASN ASN A . n 
B 2 356 TYR 356 356 356 TYR TYR A . n 
B 2 357 GLN 357 357 357 GLN GLN A . n 
B 2 358 GLY 358 358 358 GLY GLY A . n 
B 2 359 GLU 359 359 359 GLU GLU A . n 
B 2 360 GLY 360 360 360 GLY GLY A . n 
B 2 361 GLU 361 361 361 GLU GLU A . n 
B 2 362 MET 362 362 362 MET MET A . n 
B 2 363 VAL 363 363 363 VAL VAL A . n 
B 2 364 THR 364 364 364 THR THR A . n 
B 2 365 MET 365 365 365 MET MET A . n 
B 2 366 PRO 366 366 366 PRO PRO A . n 
B 2 367 ASN 367 367 367 ASN ASN A . n 
B 2 368 HIS 368 368 368 HIS HIS A . n 
B 2 369 PRO 369 369 369 PRO PRO A . n 
B 2 370 ASN 370 370 370 ASN ASN A . n 
B 2 371 LYS 371 371 371 LYS LYS A . n 
B 2 372 PRO 372 372 372 PRO PRO A . n 
B 2 373 GLU 373 373 373 GLU GLU A . n 
B 2 374 MET 374 374 374 MET MET A . n 
B 2 375 GLY 375 375 375 GLY GLY A . n 
B 2 376 SER 376 376 376 SER SER A . n 
B 2 377 ARG 377 377 377 ARG ARG A . n 
B 2 378 GLN 378 378 378 GLN GLN A . n 
B 2 379 VAL 379 379 379 VAL VAL A . n 
B 2 380 PRO 380 380 380 PRO PRO A . n 
B 2 381 PHE 381 381 381 PHE PHE A . n 
B 2 382 SER 382 382 382 SER SER A . n 
B 2 383 GLY 383 383 383 GLY GLY A . n 
B 2 384 GLU 384 384 384 GLU GLU A . n 
B 2 385 ILE 385 385 385 ILE ILE A . n 
B 2 386 TRP 386 386 386 TRP TRP A . n 
B 2 387 ILE 387 387 387 ILE ILE A . n 
B 2 388 ASP 388 388 388 ASP ASP A . n 
B 2 389 ARG 389 389 389 ARG ARG A . n 
B 2 390 ALA 390 390 390 ALA ALA A . n 
B 2 391 ASP 391 391 391 ASP ASP A . n 
B 2 392 PHE 392 392 392 PHE PHE A . n 
B 2 393 ARG 393 393 393 ARG ARG A . n 
B 2 394 GLU 394 394 394 GLU GLU A . n 
B 2 395 GLU 395 395 395 GLU GLU A . n 
B 2 396 ALA 396 396 396 ALA ALA A . n 
B 2 397 ASN 397 397 397 ASN ASN A . n 
B 2 398 LYS 398 398 398 LYS LYS A . n 
B 2 399 GLN 399 399 399 GLN GLN A . n 
B 2 400 TYR 400 400 400 TYR TYR A . n 
B 2 401 LYS 401 401 401 LYS LYS A . n 
B 2 402 ARG 402 402 402 ARG ARG A . n 
B 2 403 LEU 403 403 403 LEU LEU A . n 
B 2 404 VAL 404 404 404 VAL VAL A . n 
B 2 405 LEU 405 405 405 LEU LEU A . n 
B 2 406 GLY 406 406 406 GLY GLY A . n 
B 2 407 LYS 407 407 407 LYS LYS A . n 
B 2 408 GLU 408 408 408 GLU GLU A . n 
B 2 409 VAL 409 409 409 VAL VAL A . n 
B 2 410 ARG 410 410 410 ARG ARG A . n 
B 2 411 LEU 411 411 411 LEU LEU A . n 
B 2 412 ARG 412 412 412 ARG ARG A . n 
B 2 413 ASN 413 413 413 ASN ASN A . n 
B 2 414 ALA 414 414 414 ALA ALA A . n 
B 2 415 TYR 415 415 415 TYR TYR A . n 
B 2 416 VAL 416 416 416 VAL VAL A . n 
B 2 417 ILE 417 417 417 ILE ILE A . n 
B 2 418 LYS 418 418 418 LYS LYS A . n 
B 2 419 ALA 419 419 419 ALA ALA A . n 
B 2 420 GLU 420 420 420 GLU GLU A . n 
B 2 421 ARG 421 421 421 ARG ARG A . n 
B 2 422 VAL 422 422 422 VAL VAL A . n 
B 2 423 GLU 423 423 423 GLU GLU A . n 
B 2 424 LYS 424 424 424 LYS LYS A . n 
B 2 425 ASP 425 425 425 ASP ASP A . n 
B 2 426 ALA 426 426 426 ALA ALA A . n 
B 2 427 GLU 427 427 427 GLU GLU A . n 
B 2 428 GLY 428 428 428 GLY GLY A . n 
B 2 429 ASN 429 429 429 ASN ASN A . n 
B 2 430 ILE 430 430 430 ILE ILE A . n 
B 2 431 THR 431 431 431 THR THR A . n 
B 2 432 THR 432 432 432 THR THR A . n 
B 2 433 ILE 433 433 433 ILE ILE A . n 
B 2 434 PHE 434 434 434 PHE PHE A . n 
B 2 435 CYS 435 435 435 CYS CYS A . n 
B 2 436 THR 436 436 436 THR THR A . n 
B 2 437 TYR 437 437 437 TYR TYR A . n 
B 2 438 ASP 438 438 438 ASP ASP A . n 
B 2 439 ALA 439 439 439 ALA ALA A . n 
B 2 440 ASP 440 440 440 ASP ASP A . n 
B 2 441 THR 441 441 441 THR THR A . n 
B 2 442 LEU 442 442 442 LEU LEU A . n 
B 2 443 SER 443 443 ?   ?   ?   A . n 
B 2 444 LYS 444 444 ?   ?   ?   A . n 
B 2 445 ASP 445 445 ?   ?   ?   A . n 
B 2 446 PRO 446 446 ?   ?   ?   A . n 
B 2 447 ALA 447 447 ?   ?   ?   A . n 
B 2 448 ASP 448 448 ?   ?   ?   A . n 
B 2 449 GLY 449 449 ?   ?   ?   A . n 
B 2 450 ARG 450 450 ?   ?   ?   A . n 
B 2 451 LYS 451 451 ?   ?   ?   A . n 
B 2 452 VAL 452 452 ?   ?   ?   A . n 
B 2 453 LYS 453 453 ?   ?   ?   A . n 
B 2 454 GLY 454 454 454 GLY GLY A . n 
B 2 455 VAL 455 455 455 VAL VAL A . n 
B 2 456 ILE 456 456 456 ILE ILE A . n 
B 2 457 HIS 457 457 457 HIS HIS A . n 
B 2 458 TRP 458 458 458 TRP TRP A . n 
B 2 459 VAL 459 459 459 VAL VAL A . n 
B 2 460 SER 460 460 460 SER SER A . n 
B 2 461 ALA 461 461 461 ALA ALA A . n 
B 2 462 ALA 462 462 462 ALA ALA A . n 
B 2 463 HIS 463 463 463 HIS HIS A . n 
B 2 464 ALA 464 464 464 ALA ALA A . n 
B 2 465 LEU 465 465 465 LEU LEU A . n 
B 2 466 PRO 466 466 466 PRO PRO A . n 
B 2 467 VAL 467 467 467 VAL VAL A . n 
B 2 468 GLU 468 468 468 GLU GLU A . n 
B 2 469 ILE 469 469 469 ILE ILE A . n 
B 2 470 ARG 470 470 470 ARG ARG A . n 
B 2 471 LEU 471 471 471 LEU LEU A . n 
B 2 472 TYR 472 472 472 TYR TYR A . n 
B 2 473 ASP 473 473 473 ASP ASP A . n 
B 2 474 ARG 474 474 474 ARG ARG A . n 
B 2 475 LEU 475 475 475 LEU LEU A . n 
B 2 476 PHE 476 476 476 PHE PHE A . n 
B 2 477 SER 477 477 477 SER SER A . n 
B 2 478 VAL 478 478 478 VAL VAL A . n 
B 2 479 PRO 479 479 479 PRO PRO A . n 
B 2 480 ASN 480 480 480 ASN ASN A . n 
B 2 481 PRO 481 481 481 PRO PRO A . n 
B 2 482 GLY 482 482 482 GLY GLY A . n 
B 2 483 ALA 483 483 483 ALA ALA A . n 
B 2 484 ALA 484 484 484 ALA ALA A . n 
B 2 485 ASP 485 485 485 ASP ASP A . n 
B 2 486 ASP 486 486 486 ASP ASP A . n 
B 2 487 PHE 487 487 487 PHE PHE A . n 
B 2 488 LEU 488 488 488 LEU LEU A . n 
B 2 489 SER 489 489 489 SER SER A . n 
B 2 490 VAL 490 490 490 VAL VAL A . n 
B 2 491 ILE 491 491 491 ILE ILE A . n 
B 2 492 ASN 492 492 492 ASN ASN A . n 
B 2 493 PRO 493 493 493 PRO PRO A . n 
B 2 494 GLU 494 494 494 GLU GLU A . n 
B 2 495 SER 495 495 495 SER SER A . n 
B 2 496 LEU 496 496 496 LEU LEU A . n 
B 2 497 VAL 497 497 497 VAL VAL A . n 
B 2 498 ILE 498 498 498 ILE ILE A . n 
B 2 499 LYS 499 499 499 LYS LYS A . n 
B 2 500 GLN 500 500 500 GLN GLN A . n 
B 2 501 GLY 501 501 501 GLY GLY A . n 
B 2 502 PHE 502 502 502 PHE PHE A . n 
B 2 503 ALA 503 503 503 ALA ALA A . n 
B 2 504 GLU 504 504 504 GLU GLU A . n 
B 2 505 PRO 505 505 505 PRO PRO A . n 
B 2 506 SER 506 506 506 SER SER A . n 
B 2 507 LEU 507 507 507 LEU LEU A . n 
B 2 508 LYS 508 508 508 LYS LYS A . n 
B 2 509 ASP 509 509 509 ASP ASP A . n 
B 2 510 ALA 510 510 510 ALA ALA A . n 
B 2 511 VAL 511 511 511 VAL VAL A . n 
B 2 512 ALA 512 512 512 ALA ALA A . n 
B 2 513 GLY 513 513 513 GLY GLY A . n 
B 2 514 LYS 514 514 514 LYS LYS A . n 
B 2 515 ALA 515 515 515 ALA ALA A . n 
B 2 516 PHE 516 516 516 PHE PHE A . n 
B 2 517 GLN 517 517 517 GLN GLN A . n 
B 2 518 PHE 518 518 518 PHE PHE A . n 
B 2 519 GLU 519 519 519 GLU GLU A . n 
B 2 520 ARG 520 520 520 ARG ARG A . n 
B 2 521 GLU 521 521 521 GLU GLU A . n 
B 2 522 GLY 522 522 522 GLY GLY A . n 
B 2 523 TYR 523 523 523 TYR TYR A . n 
B 2 524 PHE 524 524 524 PHE PHE A . n 
B 2 525 CYS 525 525 525 CYS CYS A . n 
B 2 526 LEU 526 526 526 LEU LEU A . n 
B 2 527 ASP 527 527 527 ASP ASP A . n 
B 2 528 SER 528 528 528 SER SER A . n 
B 2 529 ARG 529 529 529 ARG ARG A . n 
B 2 530 HIS 530 530 530 HIS HIS A . n 
B 2 531 SER 531 531 531 SER SER A . n 
B 2 532 THR 532 532 532 THR THR A . n 
B 2 533 ALA 533 533 533 ALA ALA A . n 
B 2 534 GLU 534 534 534 GLU GLU A . n 
B 2 535 LYS 535 535 535 LYS LYS A . n 
B 2 536 PRO 536 536 536 PRO PRO A . n 
B 2 537 VAL 537 537 537 VAL VAL A . n 
B 2 538 PHE 538 538 538 PHE PHE A . n 
B 2 539 ASN 539 539 539 ASN ASN A . n 
B 2 540 ARG 540 540 540 ARG ARG A . n 
B 2 541 THR 541 541 541 THR THR A . n 
B 2 542 VAL 542 542 542 VAL VAL A . n 
B 2 543 GLY 543 543 543 GLY GLY A . n 
B 2 544 LEU 544 544 544 LEU LEU A . n 
B 2 545 ARG 545 545 545 ARG ARG A . n 
B 2 546 ASP 546 546 546 ASP ASP A . n 
B 2 547 THR 547 547 547 THR THR A . n 
B 2 548 TRP 548 548 ?   ?   ?   A . n 
B 2 549 ALA 549 549 ?   ?   ?   A . n 
B 2 550 LYS 550 550 ?   ?   ?   A . n 
B 2 551 VAL 551 551 ?   ?   ?   A . n 
B 2 552 GLY 552 552 ?   ?   ?   A . n 
B 2 553 GLU 553 553 ?   ?   ?   A . n 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
C 3 ATP 1  999 999 ATP ATP A . 
D 4 HOH 1  714 714 HOH HOH B . 
E 4 HOH 1  701 701 HOH HOH A . 
E 4 HOH 2  702 702 HOH HOH A . 
E 4 HOH 3  703 703 HOH HOH A . 
E 4 HOH 4  704 704 HOH HOH A . 
E 4 HOH 5  705 705 HOH HOH A . 
E 4 HOH 6  706 706 HOH HOH A . 
E 4 HOH 7  707 707 HOH HOH A . 
E 4 HOH 8  708 708 HOH HOH A . 
E 4 HOH 9  709 709 HOH HOH A . 
E 4 HOH 10 710 710 HOH HOH A . 
E 4 HOH 11 711 711 HOH HOH A . 
E 4 HOH 12 712 712 HOH HOH A . 
E 4 HOH 13 713 713 HOH HOH A . 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   dimeric 
_pdbx_struct_assembly.oligomeric_count     2 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_pdbx_audit_revision_history.ordinal 
_pdbx_audit_revision_history.data_content_type 
_pdbx_audit_revision_history.major_revision 
_pdbx_audit_revision_history.minor_revision 
_pdbx_audit_revision_history.revision_date 
1 'Structure model' 1 0 1996-12-07 
2 'Structure model' 1 1 2008-05-22 
3 'Structure model' 1 2 2011-07-13 
4 'Structure model' 1 3 2021-11-03 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
loop_
_pdbx_audit_revision_group.ordinal 
_pdbx_audit_revision_group.revision_ordinal 
_pdbx_audit_revision_group.data_content_type 
_pdbx_audit_revision_group.group 
1 2 'Structure model' 'Version format compliance' 
2 3 'Structure model' 'Version format compliance' 
3 4 'Structure model' 'Database references'       
4 4 'Structure model' 'Derived calculations'      
# 
loop_
_pdbx_audit_revision_category.ordinal 
_pdbx_audit_revision_category.revision_ordinal 
_pdbx_audit_revision_category.data_content_type 
_pdbx_audit_revision_category.category 
1 4 'Structure model' database_2         
2 4 'Structure model' struct_ref_seq_dif 
3 4 'Structure model' struct_site        
# 
loop_
_pdbx_audit_revision_item.ordinal 
_pdbx_audit_revision_item.revision_ordinal 
_pdbx_audit_revision_item.data_content_type 
_pdbx_audit_revision_item.item 
1 4 'Structure model' '_database_2.pdbx_DOI'                
2 4 'Structure model' '_database_2.pdbx_database_accession' 
3 4 'Structure model' '_struct_ref_seq_dif.details'         
4 4 'Structure model' '_struct_site.pdbx_auth_asym_id'      
5 4 'Structure model' '_struct_site.pdbx_auth_comp_id'      
6 4 'Structure model' '_struct_site.pdbx_auth_seq_id'       
# 
loop_
_software.name 
_software.classification 
_software.version 
_software.citation_id 
_software.pdbx_ordinal 
X-PLOR refinement       3.1 ? 1 
SDMS   'data reduction' .   ? 2 
# 
loop_
_pdbx_validate_close_contact.id 
_pdbx_validate_close_contact.PDB_model_num 
_pdbx_validate_close_contact.auth_atom_id_1 
_pdbx_validate_close_contact.auth_asym_id_1 
_pdbx_validate_close_contact.auth_comp_id_1 
_pdbx_validate_close_contact.auth_seq_id_1 
_pdbx_validate_close_contact.PDB_ins_code_1 
_pdbx_validate_close_contact.label_alt_id_1 
_pdbx_validate_close_contact.auth_atom_id_2 
_pdbx_validate_close_contact.auth_asym_id_2 
_pdbx_validate_close_contact.auth_comp_id_2 
_pdbx_validate_close_contact.auth_seq_id_2 
_pdbx_validate_close_contact.PDB_ins_code_2 
_pdbx_validate_close_contact.label_alt_id_2 
_pdbx_validate_close_contact.dist 
1 1 H   A HIS 40 ? ? HD1 A HIS 43 ? ? 1.30 
2 1 H22 B G   50 ? ? O2  B C   64 ? ? 1.40 
3 1 N1  B A   51 ? ? H3  B U   63 ? ? 1.43 
4 1 O2  B C   27 ? ? H22 B G   43 ? ? 1.44 
5 1 H22 B G   30 ? ? O2  B C   40 ? ? 1.49 
6 1 H22 B G   19 ? ? O2  B C   56 ? ? 1.50 
7 1 H62 B A   51 ? ? O4  B U   63 ? ? 1.56 
8 1 H22 B G   53 ? ? O2  B C   61 ? ? 1.56 
9 1 O2  B U   8  ? ? H61 B A   14 ? ? 1.57 
# 
loop_
_pdbx_validate_rmsd_angle.id 
_pdbx_validate_rmsd_angle.PDB_model_num 
_pdbx_validate_rmsd_angle.auth_atom_id_1 
_pdbx_validate_rmsd_angle.auth_asym_id_1 
_pdbx_validate_rmsd_angle.auth_comp_id_1 
_pdbx_validate_rmsd_angle.auth_seq_id_1 
_pdbx_validate_rmsd_angle.PDB_ins_code_1 
_pdbx_validate_rmsd_angle.label_alt_id_1 
_pdbx_validate_rmsd_angle.auth_atom_id_2 
_pdbx_validate_rmsd_angle.auth_asym_id_2 
_pdbx_validate_rmsd_angle.auth_comp_id_2 
_pdbx_validate_rmsd_angle.auth_seq_id_2 
_pdbx_validate_rmsd_angle.PDB_ins_code_2 
_pdbx_validate_rmsd_angle.label_alt_id_2 
_pdbx_validate_rmsd_angle.auth_atom_id_3 
_pdbx_validate_rmsd_angle.auth_asym_id_3 
_pdbx_validate_rmsd_angle.auth_comp_id_3 
_pdbx_validate_rmsd_angle.auth_seq_id_3 
_pdbx_validate_rmsd_angle.PDB_ins_code_3 
_pdbx_validate_rmsd_angle.label_alt_id_3 
_pdbx_validate_rmsd_angle.angle_value 
_pdbx_validate_rmsd_angle.angle_target_value 
_pdbx_validate_rmsd_angle.angle_deviation 
_pdbx_validate_rmsd_angle.angle_standard_deviation 
_pdbx_validate_rmsd_angle.linker_flag 
1 1 N9 B G 18 ? ? "C1'" B G 18 ? ? "C2'" B G 18 ? ? 123.57 114.00 9.57 1.30 N 
2 1 N9 B G 19 ? ? "C1'" B G 19 ? ? "C2'" B G 19 ? ? 123.65 114.00 9.65 1.30 N 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 ASP A 67  ? ? -100.49 65.67   
2  1 THR A 125 ? ? -67.32  -179.66 
3  1 THR A 135 ? ? -125.16 -161.58 
4  1 ASP A 147 ? ? -108.74 42.07   
5  1 ALA A 162 ? ? -79.99  22.13   
6  1 ALA A 170 ? ? -174.97 146.79  
7  1 ILE A 176 ? ? -108.71 -107.49 
8  1 GLU A 361 ? ? -95.41  -153.47 
9  1 HIS A 368 ? ? -161.89 98.70   
10 1 PRO A 369 ? ? -46.79  -14.40  
11 1 SER A 382 ? ? -164.09 -169.72 
12 1 ARG A 389 ? ? -39.02  -70.19  
13 1 ALA A 390 ? ? -50.59  1.46    
14 1 LYS A 398 ? ? -38.32  -37.84  
15 1 ARG A 402 ? ? -112.59 -141.46 
16 1 LEU A 405 ? ? -67.55  25.11   
17 1 LYS A 407 ? ? -109.01 -169.89 
18 1 ALA A 414 ? ? -130.28 -131.68 
19 1 GLU A 420 ? ? -140.88 -62.76  
20 1 GLU A 427 ? ? -84.34  45.98   
21 1 ASP A 440 ? ? -112.19 55.14   
22 1 ALA A 483 ? ? -72.75  21.58   
23 1 LEU A 507 ? ? -67.60  1.84    
24 1 LYS A 514 ? ? -167.65 88.01   
25 1 GLU A 521 ? ? -115.12 -89.12  
26 1 SER A 528 ? ? -58.76  -73.64  
27 1 ARG A 529 ? ? -30.48  -37.04  
# 
loop_
_pdbx_validate_planes.id 
_pdbx_validate_planes.PDB_model_num 
_pdbx_validate_planes.auth_comp_id 
_pdbx_validate_planes.auth_asym_id 
_pdbx_validate_planes.auth_seq_id 
_pdbx_validate_planes.PDB_ins_code 
_pdbx_validate_planes.label_alt_id 
_pdbx_validate_planes.rmsd 
_pdbx_validate_planes.type 
1 1 G B 19 ? ? 0.062 'SIDE CHAIN' 
2 1 U B 38 ? ? 0.107 'SIDE CHAIN' 
3 1 U B 47 ? ? 0.069 'SIDE CHAIN' 
4 1 C B 48 ? ? 0.060 'SIDE CHAIN' 
5 1 A B 72 ? ? 0.058 'SIDE CHAIN' 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1  1 Y 1 B U   1   ? A U   1   
2  1 Y 1 A SER 1   ? B SER 1   
3  1 Y 1 A GLU 2   ? B GLU 2   
4  1 Y 1 A ALA 3   ? B ALA 3   
5  1 Y 1 A GLU 4   ? B GLU 4   
6  1 Y 1 A ALA 5   ? B ALA 5   
7  1 Y 1 A ARG 6   ? B ARG 6   
8  1 Y 1 A PRO 7   ? B PRO 7   
9  1 Y 1 A SER 443 ? B SER 443 
10 1 Y 1 A LYS 444 ? B LYS 444 
11 1 Y 1 A ASP 445 ? B ASP 445 
12 1 Y 1 A PRO 446 ? B PRO 446 
13 1 Y 1 A ALA 447 ? B ALA 447 
14 1 Y 1 A ASP 448 ? B ASP 448 
15 1 Y 1 A GLY 449 ? B GLY 449 
16 1 Y 1 A ARG 450 ? B ARG 450 
17 1 Y 1 A LYS 451 ? B LYS 451 
18 1 Y 1 A VAL 452 ? B VAL 452 
19 1 Y 1 A LYS 453 ? B LYS 453 
20 1 Y 1 A TRP 548 ? B TRP 548 
21 1 Y 1 A ALA 549 ? B ALA 549 
22 1 Y 1 A LYS 550 ? B LYS 550 
23 1 Y 1 A VAL 551 ? B VAL 551 
24 1 Y 1 A GLY 552 ? B GLY 552 
25 1 Y 1 A GLU 553 ? B GLU 553 
# 
loop_
_ndb_struct_conf_na.entry_id 
_ndb_struct_conf_na.feature 
1QRU 'double helix'         
1QRU 'a-form double helix'  
1QRU 'hairpin loop'         
1QRU 'mismatched base pair' 
1QRU 'triple helix'         
1QRU 'four-way junction'    
# 
loop_
_ndb_struct_na_base_pair.model_number 
_ndb_struct_na_base_pair.i_label_asym_id 
_ndb_struct_na_base_pair.i_label_comp_id 
_ndb_struct_na_base_pair.i_label_seq_id 
_ndb_struct_na_base_pair.i_symmetry 
_ndb_struct_na_base_pair.j_label_asym_id 
_ndb_struct_na_base_pair.j_label_comp_id 
_ndb_struct_na_base_pair.j_label_seq_id 
_ndb_struct_na_base_pair.j_symmetry 
_ndb_struct_na_base_pair.shear 
_ndb_struct_na_base_pair.stretch 
_ndb_struct_na_base_pair.stagger 
_ndb_struct_na_base_pair.buckle 
_ndb_struct_na_base_pair.propeller 
_ndb_struct_na_base_pair.opening 
_ndb_struct_na_base_pair.pair_number 
_ndb_struct_na_base_pair.pair_name 
_ndb_struct_na_base_pair.i_auth_asym_id 
_ndb_struct_na_base_pair.i_auth_seq_id 
_ndb_struct_na_base_pair.i_PDB_ins_code 
_ndb_struct_na_base_pair.j_auth_asym_id 
_ndb_struct_na_base_pair.j_auth_seq_id 
_ndb_struct_na_base_pair.j_PDB_ins_code 
_ndb_struct_na_base_pair.hbond_type_28 
_ndb_struct_na_base_pair.hbond_type_12 
1 A G 2  1_555 A C 70 1_555 -0.264 -0.001 -0.134 -17.622 -4.044  -3.663   1  B_G2:C71_B  B 2  ? B 71 ? 19 1 
1 A G 3  1_555 A C 69 1_555 -0.624 -0.321 0.314  -3.712  -8.801  1.818    2  B_G3:C70_B  B 3  ? B 70 ? 19 1 
1 A G 4  1_555 A C 68 1_555 -0.175 -0.215 -0.045 -5.371  -11.109 0.407    3  B_G4:C69_B  B 4  ? B 69 ? 19 1 
1 A G 5  1_555 A C 67 1_555 -0.429 -0.123 -0.119 -16.279 -15.903 2.334    4  B_G5:C68_B  B 5  ? B 68 ? 19 1 
1 A U 6  1_555 A A 66 1_555 -0.053 -0.126 0.058  -11.806 -13.571 8.663    5  B_U6:A67_B  B 6  ? B 67 ? 20 1 
1 A A 7  1_555 A U 65 1_555 0.299  -0.086 -0.157 2.670   -1.136  -4.889   6  B_A7:U66_B  B 7  ? B 66 ? 20 1 
1 A C 48 1_555 A G 64 1_555 0.864  -0.576 -0.200 8.194   -11.251 -3.418   7  B_C49:G65_B B 49 ? B 65 ? 19 1 
1 A G 49 1_555 A C 63 1_555 -0.635 -0.083 0.252  -0.581  -6.037  9.908    8  B_G50:C64_B B 50 ? B 64 ? 19 1 
1 A A 50 1_555 A U 62 1_555 0.280  -0.517 0.030  -6.525  -16.660 -1.882   9  B_A51:U63_B B 51 ? B 63 ? 20 1 
1 A G 51 1_555 A C 61 1_555 -0.546 -0.130 -0.056 -7.736  -11.286 3.073    10 B_G52:C62_B B 52 ? B 62 ? 19 1 
1 A G 52 1_555 A C 60 1_555 -0.562 -0.243 0.025  -10.535 -1.974  4.321    11 B_G53:C61_B B 53 ? B 61 ? 19 1 
1 A U 53 1_555 A A 57 1_555 4.244  -2.142 -0.046 -5.469  11.006  -95.055  12 B_U54:A58_B B 54 ? B 58 ? 24 4 
1 A U 54 1_555 A G 17 1_555 0.709  -5.610 0.467  21.052  5.744   -88.172  13 B_U55:G18_B B 55 ? B 18 ? ?  2 
1 A U 37 1_555 A U 31 1_555 -3.319 -0.670 -0.692 10.462  4.489   -31.869  14 B_U38:U32_B B 38 ? B 32 ? ?  ? 
1 A U 38 1_555 A A 30 1_555 -0.276 0.410  0.962  -11.699 17.120  7.341    15 B_U39:A31_B B 39 ? B 31 ? ?  ? 
1 A C 39 1_555 A G 29 1_555 0.665  -0.194 -0.560 14.549  -2.175  6.421    16 B_C40:G30_B B 40 ? B 30 ? 19 1 
1 A C 40 1_555 A G 28 1_555 1.447  -0.619 -0.170 -1.057  -10.717 4.288    17 B_C41:G29_B B 41 ? B 29 ? 19 1 
1 A G 41 1_555 A C 27 1_555 -0.110 -0.231 -0.181 -10.675 -9.122  0.013    18 B_G42:C28_B B 42 ? B 28 ? 19 1 
1 A G 42 1_555 A C 26 1_555 -0.394 -0.414 -0.019 -10.706 -16.970 3.268    19 B_G43:C27_B B 43 ? B 27 ? 19 1 
1 A C 43 1_555 A A 25 1_555 3.537  -0.593 0.027  -7.521  -8.459  -2.437   20 B_C44:A26_B B 44 ? B 26 ? ?  1 
1 A G 10 1_555 A C 24 1_555 -0.486 -0.256 0.117  -1.761  -2.606  1.548    21 B_G10:C25_B B 10 ? B 25 ? 19 1 
1 A C 11 1_555 A G 23 1_555 0.220  -0.076 0.266  -5.154  -5.479  -0.136   22 B_C11:G24_B B 11 ? B 24 ? 19 1 
1 A C 12 1_555 A G 22 1_555 0.314  -0.319 -0.268 7.934   -9.820  -2.227   23 B_C12:G23_B B 12 ? B 23 ? 19 1 
1 A A 13 1_555 A A 44 1_555 1.446  1.357  0.098  -7.742  15.641  -172.703 24 B_A13:A45_B B 13 ? B 45 ? 1  2 
1 A A 14 1_555 A U 8  1_555 -4.025 -2.320 1.008  3.430   10.943  -89.018  25 B_A14:U8_B  B 14 ? B 8  ? 24 4 
1 A G 15 1_555 A C 47 1_555 0.147  4.176  0.101  7.532   25.492  159.591  26 B_G15:C48_B B 15 ? B 48 ? 22 2 
1 A G 18 1_555 A C 55 1_555 -0.210 -0.429 -0.529 13.566  -16.137 0.004    27 B_G19:C56_B B 19 ? B 56 ? 19 1 
# 
loop_
_ndb_struct_na_base_pair_step.model_number 
_ndb_struct_na_base_pair_step.i_label_asym_id_1 
_ndb_struct_na_base_pair_step.i_label_comp_id_1 
_ndb_struct_na_base_pair_step.i_label_seq_id_1 
_ndb_struct_na_base_pair_step.i_symmetry_1 
_ndb_struct_na_base_pair_step.j_label_asym_id_1 
_ndb_struct_na_base_pair_step.j_label_comp_id_1 
_ndb_struct_na_base_pair_step.j_label_seq_id_1 
_ndb_struct_na_base_pair_step.j_symmetry_1 
_ndb_struct_na_base_pair_step.i_label_asym_id_2 
_ndb_struct_na_base_pair_step.i_label_comp_id_2 
_ndb_struct_na_base_pair_step.i_label_seq_id_2 
_ndb_struct_na_base_pair_step.i_symmetry_2 
_ndb_struct_na_base_pair_step.j_label_asym_id_2 
_ndb_struct_na_base_pair_step.j_label_comp_id_2 
_ndb_struct_na_base_pair_step.j_label_seq_id_2 
_ndb_struct_na_base_pair_step.j_symmetry_2 
_ndb_struct_na_base_pair_step.shift 
_ndb_struct_na_base_pair_step.slide 
_ndb_struct_na_base_pair_step.rise 
_ndb_struct_na_base_pair_step.tilt 
_ndb_struct_na_base_pair_step.roll 
_ndb_struct_na_base_pair_step.twist 
_ndb_struct_na_base_pair_step.x_displacement 
_ndb_struct_na_base_pair_step.y_displacement 
_ndb_struct_na_base_pair_step.helical_rise 
_ndb_struct_na_base_pair_step.inclination 
_ndb_struct_na_base_pair_step.tip 
_ndb_struct_na_base_pair_step.helical_twist 
_ndb_struct_na_base_pair_step.step_number 
_ndb_struct_na_base_pair_step.step_name 
_ndb_struct_na_base_pair_step.i_auth_asym_id_1 
_ndb_struct_na_base_pair_step.i_auth_seq_id_1 
_ndb_struct_na_base_pair_step.i_PDB_ins_code_1 
_ndb_struct_na_base_pair_step.j_auth_asym_id_1 
_ndb_struct_na_base_pair_step.j_auth_seq_id_1 
_ndb_struct_na_base_pair_step.j_PDB_ins_code_1 
_ndb_struct_na_base_pair_step.i_auth_asym_id_2 
_ndb_struct_na_base_pair_step.i_auth_seq_id_2 
_ndb_struct_na_base_pair_step.i_PDB_ins_code_2 
_ndb_struct_na_base_pair_step.j_auth_asym_id_2 
_ndb_struct_na_base_pair_step.j_auth_seq_id_2 
_ndb_struct_na_base_pair_step.j_PDB_ins_code_2 
1 A G 2  1_555 A C 70 1_555 A G 3  1_555 A C 69 1_555 0.627  -1.780 2.927 -3.780  4.667  27.671  -4.547  -2.017 2.493 9.615   
7.787   28.303  1  BB_G2G3:C70C71_BB   B 2  ? B 71 ? B 3  ? B 70 ? 
1 A G 3  1_555 A C 69 1_555 A G 4  1_555 A C 68 1_555 0.318  -1.655 3.328 4.521   2.975  36.788  -2.994  0.106  3.205 4.683   
-7.117  37.170  2  BB_G3G4:C69C70_BB   B 3  ? B 70 ? B 4  ? B 69 ? 
1 A G 4  1_555 A C 68 1_555 A G 5  1_555 A C 67 1_555 1.086  -2.154 3.413 6.885   12.527 26.791  -6.510  -0.763 2.393 24.910  
-13.691 30.304  3  BB_G4G5:C68C69_BB   B 4  ? B 69 ? B 5  ? B 68 ? 
1 A G 5  1_555 A C 67 1_555 A U 6  1_555 A A 66 1_555 0.324  -1.178 3.319 2.802   5.302  33.113  -2.894  -0.106 3.114 9.208   
-4.867  33.637  4  BB_G5U6:A67C68_BB   B 5  ? B 68 ? B 6  ? B 67 ? 
1 A U 6  1_555 A A 66 1_555 A A 7  1_555 A U 65 1_555 -0.082 -1.247 3.056 2.569   8.661  31.908  -3.478  0.527  2.622 15.373  
-4.559  33.130  5  BB_U6A7:U66A67_BB   B 6  ? B 67 ? B 7  ? B 66 ? 
1 A A 7  1_555 A U 65 1_555 A C 48 1_555 A G 64 1_555 -0.655 -1.538 3.263 2.375   -3.761 41.530  -1.758  1.171  3.342 -5.286  
-3.338  41.757  6  BB_A7C49:G65U66_BB  B 7  ? B 66 ? B 49 ? B 65 ? 
1 A C 48 1_555 A G 64 1_555 A G 49 1_555 A C 63 1_555 0.028  -2.284 3.345 -4.103  11.006 24.537  -7.297  -0.967 2.112 24.204  
9.023   27.165  7  BB_C49G50:C64G65_BB B 49 ? B 65 ? B 50 ? B 64 ? 
1 A G 49 1_555 A C 63 1_555 A A 50 1_555 A U 62 1_555 -0.762 -1.201 3.428 2.115   6.480  37.166  -2.701  1.453  3.136 10.063  
-3.284  37.764  8  BB_G50A51:U63C64_BB B 50 ? B 64 ? B 51 ? B 63 ? 
1 A A 50 1_555 A U 62 1_555 A G 51 1_555 A C 61 1_555 0.677  -1.808 3.303 0.318   2.511  25.963  -4.680  -1.415 3.125 5.572   
-0.705  26.084  9  BB_A51G52:C62U63_BB B 51 ? B 63 ? B 52 ? B 62 ? 
1 A G 51 1_555 A C 61 1_555 A G 52 1_555 A C 60 1_555 0.861  -2.159 3.191 2.189   7.874  30.398  -5.313  -1.219 2.617 14.686  
-4.083  31.453  10 BB_G52G53:C61C62_BB B 52 ? B 62 ? B 53 ? B 61 ? 
1 A G 52 1_555 A C 60 1_555 A U 53 1_555 A A 57 1_555 -2.320 -1.783 3.221 5.945   -5.564 90.043  -1.148  1.752  3.179 -3.927  
-4.195  90.332  11 BB_G53U54:A58C61_BB B 53 ? B 61 ? B 54 ? B 58 ? 
1 A U 53 1_555 A A 57 1_555 A U 54 1_555 A G 17 1_555 1.689  -2.181 3.262 10.423  10.396 42.009  -3.834  -1.284 2.986 13.996  
-14.032 44.403  12 BB_U54U55:G18A58_BB B 54 ? B 58 ? B 55 ? B 18 ? 
1 A U 37 1_555 A U 31 1_555 A U 38 1_555 A A 30 1_555 1.895  -2.156 3.772 -19.119 11.896 42.702  -3.555  -3.784 2.147 15.145  
24.342  48.029  13 BB_U38U39:A31U32_BB B 38 ? B 32 ? B 39 ? B 31 ? 
1 A U 38 1_555 A A 30 1_555 A C 39 1_555 A G 29 1_555 -0.227 -2.103 2.293 8.514   -1.592 40.559  -2.852  0.964  2.279 -2.265  
-12.115 41.436  14 BB_U39C40:G30A31_BB B 39 ? B 31 ? B 40 ? B 30 ? 
1 A C 39 1_555 A G 29 1_555 A C 40 1_555 A G 28 1_555 -0.524 -1.520 3.551 -3.931  10.630 37.172  -3.629  0.293  3.057 16.219  
5.998   38.803  15 BB_C40C41:G29G30_BB B 40 ? B 30 ? B 41 ? B 29 ? 
1 A C 40 1_555 A G 28 1_555 A G 41 1_555 A C 27 1_555 -0.394 -2.066 3.412 0.096   10.578 15.006  -11.445 1.279  1.608 35.335  
-0.320  18.343  16 BB_C41G42:C28G29_BB B 41 ? B 29 ? B 42 ? B 28 ? 
1 A G 41 1_555 A C 27 1_555 A G 42 1_555 A C 26 1_555 0.248  -1.736 3.562 2.282   5.739  32.542  -4.059  -0.032 3.227 10.127  
-4.027  33.107  17 BB_G42G43:C27C28_BB B 42 ? B 28 ? B 43 ? B 27 ? 
1 A G 42 1_555 A C 26 1_555 A C 43 1_555 A A 25 1_555 -0.171 -1.280 3.211 3.100   5.470  44.066  -2.173  0.500  3.021 7.247   
-4.106  44.490  18 BB_G43C44:A26C27_BB B 43 ? B 27 ? B 44 ? B 26 ? 
1 A C 43 1_555 A A 25 1_555 A G 10 1_555 A C 24 1_555 -3.846 -0.913 3.335 2.606   5.802  48.281  -1.541  4.861  3.013 7.058   
-3.170  48.673  19 BB_C44G10:C25A26_BB B 44 ? B 26 ? B 10 ? B 25 ? 
1 A G 10 1_555 A C 24 1_555 A C 11 1_555 A G 23 1_555 -0.197 -1.772 3.258 0.399   1.714  41.283  -2.692  0.322  3.183 2.429   
-0.566  41.319  20 BB_G10C11:G24C25_BB B 10 ? B 25 ? B 11 ? B 24 ? 
1 A C 11 1_555 A G 23 1_555 A C 12 1_555 A G 22 1_555 0.257  -2.388 2.891 9.292   4.491  25.653  -5.919  1.359  2.392 9.633   
-19.930 27.619  21 BB_C11C12:G23G24_BB B 11 ? B 24 ? B 12 ? B 23 ? 
1 A C 12 1_555 A G 22 1_555 A A 13 1_555 A A 44 1_555 1.879  -4.412 3.435 16.554  2.635  136.689 -2.386  -0.903 3.496 1.416   
-8.896  137.175 22 BB_C12A13:A45G23_BB B 12 ? B 23 ? B 13 ? B 45 ? 
1 A A 13 1_555 A A 44 1_555 A A 14 1_555 A U 8  1_555 -0.766 3.045  3.094 -7.712  -0.667 -36.888 -4.635  -2.117 2.933 1.040   
-12.025 -37.664 23 BB_A13A14:U8A45_BB  B 13 ? B 45 ? B 14 ? B 8  ? 
1 A A 14 1_555 A U 8  1_555 A G 15 1_555 A C 47 1_555 1.477  -3.119 3.145 -1.083  19.413 -73.143 1.917   1.173  3.776 -16.017 
-0.894  -75.333 24 BB_A14G15:C48U8_BB  B 14 ? B 8  ? B 15 ? B 48 ? 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
3 "ADENOSINE-5'-TRIPHOSPHATE" ATP 
4 water                       HOH 
# 
